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Books on the topic 'GABA Neurotransmitter receptors'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

NATO Advanced Research Workshop on Molecular Biology of Neuroreceptors and Ion Channels (1988 Thera Island, Greece). Molecular biology of neuroreceptors and ion channels. Springer-Verlag, 1989.

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2

Hydén, Holger. Regulation of inhibition by neuronal GABA r receptor interaction. Kungl. Vetenskaps-och vitterhets-samhället, 1991.

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3

(Editor), Arne Schousboe, and Hans Bräuner-Osborne (Editor), eds. Molecular Neuropharmacology: Strategies and Methods. Humana Press, 2003.

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4

Schousboe, Arne, and Hans Bräuner-Osborne. Molecular Neuropharmacology: Strategies and Methods. Humana, 2010.

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5

Nutt, David J., and Liam J. Nestor. The GABA system and addiction. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198797746.003.0008.

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Research points to the potential role of gamma-aminobutyric acid (GABA) in substance addiction. GABA is the major inhibitory neurotransmitter in the brain. Disturbances in the GABA system may predate substance abuse and addiction, whereby its efficacy to modulate other neurotransmitter systems (e.g. dopamine) strongly implicated in substance addiction behaviours is impaired. There are a number of addictive substances that boost GABA functioning, however, such as alcohol and benzodiazepines. Medications that boost the availability of GABA or mimic its effects at receptors may possess some clini

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6

S, Smith Sheryl, ed. Neurosteroid effects in the central nervous system: The role of the GABA-A receptor. CRC Press, 2003.

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7

Pharmacology of GABA and Glycine Neurotransmission. Springer, 2001.

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8

Naylor, Jennifer Camille. Systemic and local application of ethanol inhibits spontaneous activity of central nucleus of the amygdala neurons via potentiation of GABA but not serotonin. 2002.

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9

Nielsen, David A., Dmitri Proudnikov, and Mary Jeanne Kreek. The Genetics of Impulsivity. Edited by Jon E. Grant and Marc N. Potenza. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195389715.013.0080.

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Impulsivity is a complex trait that varies across healthy individuals, although when excessive, it is generally regarded as dysfunctional. Impulsive behavior may lead to initiation of drug addiction that interferes with inhibitory controls, which may in turn result in facilitation of the individual’s impulsive acts. Although environmental factors play a considerable role in impulsive behavior, a body of evidence collected in twin studies suggests that about 45% of the variance in impulsivity is accounted for by genetic factors. Genetic variants studied in association with impulsivity include t

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10

Narayana, Shalini, Andrew B. Newberg, and Abass Alavi. Positron Emission Tomography. Edited by Andrew C. Papanicolaou. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199764228.013.9.

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This chapter describes the application of positron emission tomography (PET) technology to study neurotransmitter systems. The process of developing radiotracers to study the neurotransmitter systems, namely radioligands and the technical aspects of utilizing these radiotracers in PET imaging, is discussed. Normal distribution of neurotransmitters including dopamine, serotonin, opioids, and γ-aminobutyric acid (GABA), as well as abnormalities of these systems in various neurological and psychiatric disorders, are highlighted. The chapter provides evidence that radioligand imaging has been usef

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11

1947-, Turner A. J., and Stephenson F. Anne, eds. Amino acid neurotransmission. Portland Press, 1998.

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12

Giovanni, Biggio, Costa Erminio, and Capo Boi Conference on Neuroscience (5th : 1987 : Villasimius, Italy), eds. Chloride channels and their modulation by neurotransmitters and drugs. Raven Press, 1988.

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13

G, Avanzini, ed. Neurotransmitters in epilepsy. Elsevier, 1992.

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14

(Editor), David L. Martin, and Richard W. Olsen (Editor), eds. GABA in the Nervous System: The View at Fifty Years. Lippincott Williams & Wilkins, 2000.

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15

Nutt, David J., and Liam J. Nestor. Conclusion and overview. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198797746.003.0013.

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Substance addiction is a chronic relapsing disorder. It is the manifestation of the long-term pharmacological actions of substances on the receptor mechanisms of the brain’s neural circuitry. There are different neurotransmitter systems (e.g. dopamine, GABA, opioids) and even appetite hormones, acting within this neural circuitry in addiction, but their collective roles in the disorder remain equivocal. Importantly, disturbances to these systems may also pre-date addiction, which leads people to initiate substance abuse (e.g. stress, reward sensitivity). People may also be at an increased risk

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16

Jerome, Engel, ed. Molecular neurobiology of epilepsy. Elsevier, 1992.

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17

Takao, Kumazawa, Kruger Lawrence, and Mizumura Kazue, eds. The polymodal receptor: A gateway to pathological pain. Elsevier, 1996.

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18

(Editor), T. Kumazawa, L. Kruger (Editor), and K. Mizumura (Editor), eds. The Polymodal Receptor - A Gateway to Pathological Pain (Progress in Brain Research). Elsevier Science, 1996.

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