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Dissertations / Theses on the topic 'GABA Neurotransmitter receptors'

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1

Quesada, Macarena Peran. "Cellular distribution and immobilisation of GABA(_A) receptors." Thesis, Durham University, 2000. http://etheses.dur.ac.uk/4611/.

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Synaptic inhibition in the vertebrate central nervous system is largely mediated by type A GABA receptors (GABA(_A)R). The clustering of (GABA(_A)R) at discrete and functionally significant domains on the nerve cell surface is an important determinant in the integration of synaptic inputs. To discern the role that specific GABA(_A)R subunits play in determining the receptor's cell surface topography and mobility, recombinant GABA(_A)Rs, comprising different GABA(_A)R subunit combinations, were transiently expressed in COS7, HEK293 and PC12 cells. In addition, a series of domain swapping experi
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2

Shi, Haifeng. "Structural studies on GABAA̳ receptor and glycine receptor /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?BICH%202002%20SHI.

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Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2002.<br>On t.p. "A̳" is subsript. Includes bibliographical references (leaves 160-177). Also available in electronic version. Access restricted to campus users.
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3

Smith, Anthony Donald. "Temporal resolution and determination of the mechanism of ethanol-induced taurine efflux." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0004357.

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Thesis (Ph.D.)--University of Florida, 2005.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 165 pages. Includes Vita. Includes bibliographical references.
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4

Gueydan, Marine. "Identification de nouveaux régulateurs de la synaptogénèse GABAergique à la jonction neuromusculaire du nématode Caenorhabditis elegans." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1202.

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Afin d’identifier de nouveaux régulateurs impliqués dans le contrôle du nombre des RGABAs à la synapse, nous avons utilisé la jonction neuromusculaire GABAergique du nématode Caenorhabditis elegans comme système modèle. Après mutagénèse aléatoire d’une souche knock-in exprimant les RGABAs tagués avec une protéine fluorescente (TagRFP), nous avons isolé plusieurs mutants présentant des défauts de localisation des récepteurs. Nous avons mis au point une nouvelle stratégie, basée sur l’analyse bio-informatique de données issues du séquençage du génome entier (WGS), en combinant identification et
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5

Ong, Jennifer. "GABA and GABA-receptors in the enteric nervous system /." Title page, contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09pho582.pdf.

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6

Thompson, Sally-Anne. "Pharmacological properties of recombinant human GABA←A receptors." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272213.

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7

Hutton, Michael Leslie. "Molecular biology of GABA and L-glutamate receptors in the mollusc Lymnaea stagnalis." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308303.

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8

Glencorse, Thora Ann. "Molecular biology of the chicken brain GABA←A receptor." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240925.

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9

Cao, Yu. "Morphological and functional characterization of the neurotransmitter GABA in adult rat taste buds." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1141853118.

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10

Wall, Mark John. "Modulation of the swimming motor pattern in Xenopus embryos of GABA←B receptors and by direct reduction of potassium currents." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358228.

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11

Ring, Henrik. "Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System." Doctoral thesis, Uppsala universitet, Medicinsk utvecklingsbiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180011.

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One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. In particular, this knowledge will be important in the establishment of protocols that produce sufficient numbers of specific neurons. The main aim of this thesis was to find and characterise factors regulating the proliferation and differentiation of retinal progenitor cells (RPCs) and hence,
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12

Alasmari, Fawaz Fayez. "Chronic Exposure to Electronic Cigarette Vapor-Containing Nicotine and Co-Exposure to Alcohol and Nicotine: Effects on Glial Glutamate Transporters, Nicotinic Receptors and Neurotransmitters." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1525349376479605.

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13

Kantamneni, Sriharsha, I. M. Gonzàlez-Gonzàlez, J. Luo, et al. "Differential regulation of GABAB receptor trafficking by different modes of N-methyl-D-aspartate (NMDA) receptor signaling." 2013. http://hdl.handle.net/10454/8125.

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yes<br>Inhibitory GABAB receptors (GABABRs) can down-regulate most excitatory synapses in the CNS by reducing postsynaptic excitability. Functional GABABRs are heterodimers of GABAB1 and GABAB2 subunits and here we show that the trafficking and surface expression of GABABRs is differentially regulated by synaptic or pathophysiological activation of NMDA receptors (NMDARs). Activation of synaptic NMDARs using a chemLTP protocol increases GABABR recycling and surface expression. In contrast, excitotoxic global activation of synaptic and extrasynaptic NMDARs by bath application of NMDA causes the
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14

Maric, Hans-Michael. "Molecular Basis of the Multivalent Glycine and γ-Aminobutyric Acid Type A Receptor Anchoring". Doctoral thesis, 2012. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-85712.

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γ-Aminobuttersäure-Rezeptoren vom Typ A (GABAARs) und Glyzin-Rezeptoren (GlyRs) sind die wichtigsten Vermittler der schnellen synaptischen Inhibition im zentralen Nervensystem. Von wesentlicher Bedeutung für ihre ordnungsgemäße Funktion in der inhibitorischen Signalübertragung ist ihre präzise Lokalisation und Konzentration innerhalb der neuronalen Oberflächenmembran. Diese Eigenschaften werden durch Gerüstproteine vermittelt, welche direkt an die großen intrazellulären Schleifen der Rezeptoren, sowie an Bausteine des neuronalen Zytoskeletts binden. In meiner Dissertation habe ich die molekula
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15

Holden, Jessica H. "Contributions of the GABAa receptor [alpha]₁ subunit to the structure and dynamics of the neurotransmitter binding pocket." 2003. http://www.library.wisc.edu/databases/connect/dissertations.html.

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