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Journal articles on the topic 'GABHS'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Brook, Itzhak, та Alan E. Gober. "Recovery of interfering and β-lactamase-producing bacteria from group A β-haemolytic streptococci carriers and non-carriers". Journal of Medical Microbiology 55, № 12 (2006): 1741–44. http://dx.doi.org/10.1099/jmm.0.46796-0.

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The purpose of this study was to compare the frequency of recovery of aerobic and anaerobic organisms with interfering capability against group A β-haemolytic streptococci (GABHS) and β-lactamase-producing bacteria (BLPB) from the tonsils of GABHS carriers and non-carriers. The presence of aerobic and anaerobic bacteria capable of such interference in vitro was evaluated in cultures obtained from the tonsils of 20 healthy children who were non-GABHS carriers and 20 who were GABHS carriers, and also from 20 children who were asymptomatic after completing a course of penicillin for acute GABHS p

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2

Gerber, Michael A. "Antibiotic Resistance: Relationship to Persistence of Group A Streptococci in the Upper Respiratory Tract." Pediatrics 97, no. 6 (1996): 971–75. http://dx.doi.org/10.1542/peds.97.6.971.

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Despite the use of penicillin for more than 40 years in treating GABHS infections, there has been no significant change in the in vitro susceptibility of GABHS to penicillin. Reported failures to eradicate GABHS from the upper respiratory tracts of patients with pharyngitis and the apparent resurgence of serious Group A streptococcal infections and their sequelae probably are not related to the emergence of penicillin resistance. Although erythromycin resistance in GABHS had been a major problem in Japan and continues to be a major problem in Finland, it has not been a problem in this country.

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3

Brook, Itzhak, та Alan E. Gober. "Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A β-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis". Journal of Medical Microbiology 55, № 8 (2006): 989–92. http://dx.doi.org/10.1099/jmm.0.46325-0.

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The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A β-haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of Moraxella catarrhalis, Haemophilus influenzae, Staphylococcus aureus and Streptococcus pneumoniae in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healt

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4

Dargad, Ramesh. "Role of penicillin in the management of group A beta-hemolytic streptococcal pharyngitis." International Journal of Advances in Medicine 10, no. 5 (2023): 433–40. http://dx.doi.org/10.18203/2349-3933.ijam20231081.

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Group A beta-hemolytic streptococcal (GABHS) infection is the most common bacterial cause of acute pharyngitis. GABHS is more commonly seen in the pediatric age group than in adults. The disease responds to antibiotics. Untreated GABHS leads to non-suppurative and suppurative complications. Penicillin is the drug of choice recommended by most guidelines. Most GABHS isolates are sensitive to penicillin including penicillin G. Penicillins play a very important role in preventing transmission rates of GABHS, resolution of symptoms, and prevention of GABHS complications. Intramuscular penicillin G

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5

Brook, Itzhak. "Treatment Challenges of Group A Beta-hemolytic Streptococcal Pharyngo-Tonsillitis." International Archives of Otorhinolaryngology 21, no. 03 (2016): 286–96. http://dx.doi.org/10.1055/s-0036-1584294.

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Introduction Despite its in vitro efficacy, penicillin often fails to eradicate Group A β-hemolytic streptococci (GABHS) from patients with acute and relapsing pharyngo-tonsillitis (PT). Objective This review of the literature details the causes of penicillin failure to eradicate GABHS PT and the therapeutic modalities to reduce and overcome antimicrobial failure. Data Synthesis The causes of penicillin failure in eradicating GABHS PT include the presence of β lactamase producing bacteria (BLPB) that “protect” GABHS from any penicillin; the absence of bacteria that interfere with the growth of

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6

Maltseva, G. S., and O. N. Grinchuk. "Role of antibiotic therapy in the treatment of streptococcal infection." Medical Council, no. 20 (November 16, 2019): 91–96. http://dx.doi.org/10.21518/2079-701x-2019-20-91-96.

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The article states the principles for antibiotic therapy for chronic tonsillitis (CT) and acute tonsillopharyngitis (ATP). The greatest attention is paid to the non-angina CT, when the patients, as a general rule, are deprived of antibiotic therapy. At the same time, the article provides data of St. Petersburg Research Institute of ENT, whereby at least 40% of patients with CT have streptococcal etiology of the disease caused by group A beta-hemolytic streptococci (GABHS) that is confirmed by not only bacteriological, but also immunological research methods (increase in antistreptolysin-O). In

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Brook, Itzhak, and Paula Yocum. "Comparison of the Microbiology of Group a and Non-Group a Streptococcal Tonsillitis." Annals of Otology, Rhinology & Laryngology 97, no. 3 (1988): 243–46. http://dx.doi.org/10.1177/000348948809700306.

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We studied the microbial flora of tonsils removed from 20 children who suffered from recurrent group A β-hemolytic streptococcal (GABHS) tonsillitis and 20 who had tonsillar hypertrophy following recurrent non-GABHS tonsillitis. Similar polymicrobial aerobic and anaerobic flora were recovered from the cores of the tonsils in each group. β-Lactamase-producing bacteria (BLPB) were recovered more often in the group with GABHS. This difference was due mostly to the lower incidence of β-lactamase-producing strains of Branhamella catarrhalis and Bacteroides sp in hypertrophic tonsils following non-G

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8

Brundage, John F., Jeffrey D. Gunzenhauser, Jenice N. Longfield, et al. "Epidemiology and Control of Acute Respiratory Diseases With Emphasis on Group A Beta-Hemolytic Streptococcus: A Decade of U.S. Army Experience." Pediatrics 97, no. 6 (1996): 964–70. http://dx.doi.org/10.1542/peds.97.6.964.

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Objective. To summarize the experiences of the U.S. Army regarding prevention and control, and frequencies, rates, trends, and determinants of febrile acute respiratory diseases (ARDs), particularly Group A beta-hemolytic streptococcus (GABHS). Methodology. Since 1966, the U.S. Army has conducted routine surveillance of ARDs among basic trainees. Since 1985, all trainees with fever and respiratory tract symptoms have been cultured for GABHS. Field investigations were conducted when outbreaks of acute respiratory or GABHS-associated illnesses were detected. Mass plus tandem benzathine penicilli

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9

Rathore, Mobeen H., Leslie L. Barton та Edward L. Kaplan. "Suppurative Group A β-Hemolytic Streptococcal Infections in Children". Pediatrics 89, № 4 (1992): 743–46. http://dx.doi.org/10.1542/peds.89.4.743.

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Group A β-hemolytic streptococci (GABHS) have once again become an important cause of serious suppurative disease in children. A 100% increase in the rate of GABHS bacteremia and an increased frequency in GABHS bacteremia in previously healthy children were observed in 1989 through 1990 compared with 1984 to 1988. Streptococcal isolates were characterized and patient demographic data were tabulated from children hospitalized with GABHS suppurative infections in 1989 through 1990. The differences in clinical manifestations and strains of GABHS were examined in patients with bacteremia, with or

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10

Sarrell, E. Michael, and Shmuel M. Giveon. "Streptococcal Pharyngitis: A Prospective Study of Compliance and Complications." ISRN Pediatrics 2012 (June 21, 2012): 1–8. http://dx.doi.org/10.5402/2012/796389.

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Background. Uncertainty exists concerning the necessity of 10-day antibiotic treatment of group A beta hemolytic streptococcus (GABHS) pharyngitis. Objective. To assess the incidence of GABHS recurrence and suppurative and nonsuppurative complications in relation to compliance. Methods. (Design). Prospective cohort observational study. (Subjects). 2,000 children aged 6 months to 18 years with sore throat and positive GABHS culture. (Main Outcome Measures). Recurrence of symptomatic culture positive GABHS pharyngitis, incidence of suppurative, and long-term, regional, nonsuppurative complicatio

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11

Andrews, Megan, and Michelle Condren. "Once-Daily Amoxicillin for Pharyngitis." Journal of Pediatric Pharmacology and Therapeutics 15, no. 4 (2010): 244–48. http://dx.doi.org/10.5863/1551-6776-15.4.244.

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ABSTRACT A once-daily antibiotic regimen for group A β-hemolytic streptococcal pharyngitis (GABHS) could improve compliance and be effective in the prevention of rheumatic fever, a dangerous complication of untreated or poorly treated GABHS. Amoxicillin is ideal for once-daily dosing due to its low cost. Azithromycin, cefadroxil, ceftibuten, cefixime and extended release amoxicillin are also FDA approved to treat GABHS once daily; however, even when taken for short courses, these antibiotics are more expensive compared with a oncedaily dosing of conventional amoxicillin for 10 days. The Americ

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12

Doctor, Allan, Marvin B. Harper, and Gary R. Fleisher. "Letter To The Editor." Pediatrics 98, no. 2 (1996): 315. http://dx.doi.org/10.1542/peds.98.2.315.

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We agree with Dr Goldsmith's caution in projecting trends from any case series. We would also like to take this opportunity to present the incidence of group A β-hemolytic streptococcus (GABHS) complications in children with varicella-zoster virus (VZV) at our institution since the data collection period of our prior study.1 In 1994, there were four children with GABHS bacteremia, none with VZV; in addition, four children were hospitalized with GABHS complications (cultures of sterile sites other than blood) during VZV infection (two with osteomyelitis, two with deep abscesses).

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13

Doctor, Allan, Marvin B. Harper та Gary R. Fleisher. "Group A β-Hemolytic Streptococcal Bacteremia: Historical Overview, Changing Incidence, and Recent Association With Varicella". Pediatrics 96, № 3 (1995): 428–33. http://dx.doi.org/10.1542/peds.96.3.428.

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Objective. To quantitate the increase in invasive group A β-hemolytic streptococcal (GABHS) infections and to define a possible association between GABHS bacteremia and primary varicella zoster virus (VZV) infections. Methods. This was a retrospective chart review conducted at Children's Hospital. Participants were patients with documented GABHS bacteremia occurring from January 1977 through December 1993. Measurements/Main Results. We identified 63 episodes of GABHS bacteremia in 62 patients. From 1977 to 1992, a mean of 3.2 ± 2 cases occurred per year (range, 0 to 6), increasing by a factor

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14

Kikuta, Hideaki, Mutsuo Shibata, Shuji Nakata та ін. "Comparative Study of 5-Day and 10-Day Cefditoren Pivoxil Treatments for Recurrent Group Aβ-HemolyticStreptococcus pharyngitisin Children". International Journal of Pediatrics 2009 (2009): 1–5. http://dx.doi.org/10.1155/2009/863608.

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Efficacy of short-course therapy with cephalosporins for treatment of group Aβ-hemolytic streptococcus (GABHS) pharyngitis is still controversial. Subjects were 226 children with a history of at least one episode of GABHS pharyngitis. Recurrence within the follow-up period (3 weeks after initiation of therapy) occurred in 7 of the 77 children in the 5-day treatment group and in 1 of the 149 children in the 10-day treatment group; the incidence of recurrence being significantly higher in the 5-day treatment group. Bacteriologic treatment failure (GABHS isolation without overt pharyngitis) at fo

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15

Folić, Miljan, Marko Folić, and Ana Tomić. "Recurrent acute tonsillitis: Therapeutic challenges." Galenika Medical Journal 1, no. 4 (2022): 26–32. http://dx.doi.org/10.5937/galmed2204028f.

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Introduction: Acute tonsillopharyngitis is one of the most common infections of the upper respiratory tract, and in a number of patients a relapse of the infection may occur shortly after the termination of antibiotic treatment. It is more likely that recurrent acute tonsillopharyngitis (RATP) is primarily a result of therapeutic failure in pathogen eradication. Penicillin failure in the treatment of bacterial tonsillopharyngitis. The explanation for the penicillin failure in the treatment of bacterial tonsillopharyngitis should be sought in its inability to eradicate intracellular beta-hemoly

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TUCKER, MIRIAM E. "Cephalosporins Superior for GABHS." Family Practice News 36, no. 3 (2006): 26. http://dx.doi.org/10.1016/s0300-7073(06)72617-2.

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17

Willis, Brian H., Dyuti Coomar, and Mohammed Baragilly. "Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds." British Journal of General Practice 70, no. 693 (2020): e245-e254. http://dx.doi.org/10.3399/bjgp20x708833.

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BackgroundCentor and McIsaac scores are both used to diagnose group A beta-haemolytic streptococcus (GABHS) infection, but have not been compared through meta-analysis.AimTo compare the performance of Centor and McIsaac scores at diagnosing patients with GABHS presenting to primary care with pharyngitis.Design and settingA meta-analysis of diagnostic test accuracy studies conducted in primary care was performed using a novel model that incorporates data at multiple thresholds.MethodMEDLINE, EMBASE, and PsycINFO were searched for studies published between January 1980 and February 2019. Include

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18

Landolt and Heininger. "Prävalenz der streptogenen perianalen Dermatitis bei Kindern und Jugendlichen." Praxis 94, no. 38 (2005): 1467–71. http://dx.doi.org/10.1024/0369-8394.94.38.1467.

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Die perianale streptogene Dermatitis (PSD), hervorgerufen durch beta-hämolysierende Streptokokken der Gruppe A (GABHS), ist ein wenig erkanntes Krankheitsbild. Wir führten eine Untersuchung zur Prävalenzerhebung der PSD am Universitäts-Kinderspital beider Basel (UKBB) im Zeitraum Oktober 2000 bis Mitte Mai 2001 durch. Dabei wurden 250 zufällig ausgesuchte Patienten anamnestisch, klinisch und bakteriologisch auf Vorliegen einer PSD untersucht. Gleichzeitig wurde ein Rachenabstrich zum Nachweis von GABHS durchgeführt. Bei 12 Patienten (7 Mädchen, 5 Knaben) fanden sich GABHS im Perianalabstrich,

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Sevinc, Irfan, and Murat Enoz. "The Incidence of Group A Beta Hemolytic Streptococci in Throat Specimens from Upper Respiratory Infections." Acta Medica (Hradec Kralove, Czech Republic) 50, no. 4 (2007): 243–44. http://dx.doi.org/10.14712/18059694.2017.92.

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Objective: The aim of the study is researching the incidence of group A beta hemolytic streptococci (GABHS) in upper respiratory tract infections in Turkey. Study design: This is a descriptive study. Subject and Methods: Totally, 3964 throat swabs obtained from patients with upper respiratory tract infections were cultured for isolation of GABHS in Corlu Military Hospital, Department of Microbiology, between April 2002 and April 2004. Standard microbiological techniques were used in the screening. Results: In this study, GABHS were isolated from 230 (5.80 %) of 3964 patients. The rate of isola

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Diong, Sophie, Michéal O’Rourke, Colm Bergin, Niamh Leonard, Bairbre Wynne, and Patrick Ormond. "BI28 Invasive streptococcal infection in a patient with HIV." British Journal of Dermatology 191, Supplement_1 (2024): i151. http://dx.doi.org/10.1093/bjd/ljae090.316.

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Abstract A spectrum of severity exists in cutaneous infections with group A β-haemolytic streptococci (GABHSs), including life-threatening streptococcal toxic shock syndrome (STSS), which can follow minor trauma to skin or mucosa. We present a case of STSS with resultant necrotizing ecthyma-type infraorbital ulceration and necrotizing lymphadenitis in a patient with HIV. A 37-year-old Nigerian woman of no fixed abode presented with florid head and neck oedema, and vasopressor-dependent hypotension 1 day after accidental ocular inoculation with a camphor-based product, causing excoriation-induc

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Gunnarsson, Ronny, Ulrich Orda, Bradley Elliott, Clare Heal, and Chris Del Mar. "What is the optimal strategy for managing primary care patients with an uncomplicated acute sore throat? Comparing the consequences of nine different strategies using a compilation of previous studies." BMJ Open 12, no. 4 (2022): e059069. http://dx.doi.org/10.1136/bmjopen-2021-059069.

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ObjectiveIdentifying optimal strategies for managing patients of any age with varying risk of acute rheumatic fever (ARF) attending for an apparently uncomplicated acute sore throat, also clarifying the role of point-of-care testing (POCT) for presence of group A beta-haemolytic Streptococcus (GABHS) in these settings.DesignWe compared outcomes of adhering to nine different strategies for managing these patients in primary healthcare.Setting and participantsThe nine strategies, similar to guidelines from several countries, were tested against two validation data sets being constructs from seve

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Santalova, G. V., P. A. Lebedev, A. A. Garanin, A. V. Lyamin та M. E. Kuzin. "Cardiac and non-cardiac manifestations of infection caused by group A β-hemolytic Streptococcus". Russian Journal of Woman and Child Health 5, № 1 (2022): 63–71. http://dx.doi.org/10.32364/2618-8430-2022-5-1-63-71.

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Infection caused by group A β-hemolytic Streptococcus (GABHS) is characterized by significant diversity of clinical presentations accounted for by different GABHS strains and individual patients’ predisposition to immune inflammation. This paper reviews current data on streptococcal infection and poststreptococcal cardiac and non-cardiac complications and describes early diagnostic tools. Superficial infections are the most common forms (particularly in pediatrics) manifested as pharyngitis, tonsillitis, otitis, or sinusitis. Invasive infections (pneumonia, necrotizing fasciitis) are potential

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Brook, Itzhak, and Kiran Shah. "Bacteriology of Adenoids and Tonsils in Children with Recurrent Adenotonsillitis." Annals of Otology, Rhinology & Laryngology 110, no. 9 (2001): 844–48. http://dx.doi.org/10.1177/000348940111000908.

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Adenoids and tonsils electively removed from 25 children with a history of recurrent group A β-hemolytic streptococci (GABHS) adenotonsillitis were cultured for aerobic and anaerobic bacteria. Two hundred twenty-four organisms (112 aerobes and facultatives, 110 anaerobes, and 2 Candida albicans) were isolated from the tonsils, and 229 (111 aerobes and facultatives and 118 anaerobes) were isolated from the adenoids. Mixed infection was present in all instances, with an average of 9.1 isolates per specimen. The predominant aerobes were Streptococcus sp, Haemophilus influenzae, and GABHS, and the

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Shrestha, Lochana, J. B. Khattri, K. N. Brahmadathan, and J. S. Nagra. "PREVALENCE OF STREPTOCOCCAL PHARYNGITIS AMONG SCHOOL CHILDREN OF POKHARA VALLEY, NEPAL." Journal of Nepal Medical Association 41, no. 141 (2003): 253–57. http://dx.doi.org/10.31729/jnma.737.

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Group A Beta Haemolytic Streptococcal (GABHS) infections and their sequelaeRheumatic fever (RF) and Glomerulonephritis (GN) have a world wide distributionand pose an important health problem. Present study intended to find out the prevalenceofGABHS pharyngitis among school children in the Pokhara Valley, Nepal. It was across sectional, observational study. During 7 months period total 750 children wereexamined from six government primary schools. 25.3% were found to have symptomsof clinical pharyngitis and the prevalence of GABHS pharyngitis was 7.2% amongthese school children. GABHS pharyngit

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Rano, Aditomo. "Systemic Complications of Streptococci in Chronic Tonsillitis: Case Series." International Journal of Contemporary Research in Multidisciplinary 3, no. 2 (2024): 16–19. https://doi.org/10.5281/zenodo.10794541.

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Streptolysin O is one of the toxins produced from Group A Beta Hemolytic Streptococcal (GABHS) infection. In the human body infected with GABHS will produce a natural antigen, namely anti-Streptolysin titer O (ASTO). <sup>[1]</sup> Throat culture is performed to determine the presence of group A Streptococci in the upper respiratory tract. Throat cultures have a sensitivity of about 90% - 95% in detecting the presence of GABHS. The purpose of writing this case report is to provide knowledge to peers about systemic complications resulting from Streptococcal infection in tonsillitis. It has been

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TUCKER, MIRIAM E. "Metronidazole Treats Non-GABHS Tonsillitis." Pediatric News 39, no. 2 (2005): 12. http://dx.doi.org/10.1016/s0031-398x(05)70410-0.

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Tack, Kenneth J., Daniel C. Henry, W. Manford Gooch, Douglas N. Brink, Constance H. Keyserling, and The Cefdinir Pharyngitis Study Group. "Five-Day Cefdinir Treatment for Streptococcal Pharyngitis." Antimicrobial Agents and Chemotherapy 42, no. 5 (1998): 1073–75. http://dx.doi.org/10.1128/aac.42.5.1073.

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ABSTRACT A multicenter, randomized, controlled, investigator-blind study was performed to evaluate the safety and efficacy of oral cefdinir versus oral penicillin V for the treatment of pharyngitis due to group A beta-hemolytic streptococci (GABHS). Patients 13 years of age and older were randomized to receive either oral cefdinir (300 mg twice a day) for 5 days followed by placebo for 5 days or oral penicillin V (250 mg four times a day) for 10 days. Throat cultures were obtained, and signs and symptoms of pharyngitis were recorded at study admission and follow-up visits on study days 11 to 1

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BALCI, Pervin. "Erythromycin resistance in Group A Beta-hemolytic streptococci." Anatolian Current Medical Journal 4, no. 4 (2022): 421–25. http://dx.doi.org/10.38053/acmj.1166370.

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Aim: Streptococcus pyogenes (Group A Beta-hemolytic streptococci, GABHS) is one of the important bacterial pathogens in clinical microbiology. It often causes upper respiratory tract infections such as tonsillitis, pharyngitis, and laryngitis. It also leads to complications such as acute rheumatic fever and post-streptococcal glomerulonephritis. Early diagnosis and treatment of these bacterial infections will prevent suppurative and non-suppurative complications, the transmission of infection to other people, and chronic carriage. Today, the treatment of streptococcal infections relies entirel

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Paradise, Jack L. "Etiology and Management of Pharyngitis and Pharyngotonsillitis in Children: A Current Review." Annals of Otology, Rhinology & Laryngology 101, no. 1_suppl (1992): 51–57. http://dx.doi.org/10.1177/00034894921010s111.

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Although viruses are the most common causes of childhood throat infections, interest in the etiology of these infections has primarily focused on whether an individual episode is caused by group A β-hemolytic streptococcus (GABHS), particularly since the recent outbreaks of rheumatic fever in certain areas of the country. Penicillin remains the cornerstone of treatment in GABHS pharyngitis. Early treatment effects prompt clinical improvement and reduces the risk of transmission. Whether early treatment suppresses immunologic response and results in a higher recurrence rate than does delayed tr

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Cengel-Kültür, S. Ebru, Esra Cöp, Ateş Kara, Ali Bülent Cengiz, Ali Kerem Uludağ, and Fatih Unal. "The relationship between group A beta hemolytic streptococcal infection and psychiatric symptoms: a pilot study." Turkish Journal of Pediatrics 51, no. 4 (2009): 317–24. http://dx.doi.org/10.24953/turkjped.2009.2309.

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The aim of this study was to test if children with group A beta hemolytic streptococcal infection (GABHS) are more likely to develop neuropsychiatric symptoms or the syndrome of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection (PANDAS) compared to children with GABHS-negative throat cultures. Children aged 8 to 12 years (n = 81) with upper respiratory tract infection were assessed with the Schedule for Affective Disorders and Schizophrenia for School-Age Children - Present and Lifetime Version, Children's Yale Brown Obsession Compulsion Scale, Yale Global

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KYRIAZI, NICHOLAS C., та CYNTHIA L. COSTENBADER. "Group A β-Hemolytic Streptococcal Balanitis: It May Be More Common Than You Think". Pediatrics 88, № 1 (1991): 154–56. http://dx.doi.org/10.1542/peds.88.1.154.

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Group A β-hemolytic Streptococcus can cause balanitis in prepubertal males, and its incidence is probably greater than previously reported in the pediatric literature. We suggest the routine inclusion of a GABHS-selective culture in any case where a discharge or irritation is present on the glans or foreskin, especially if a recent streptococcal infection has been documented, whether on not sexual abuse is being considered. Finally, we hope to stimulate interest for further in-depth study of balanitis caused by GABHS.

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Chiesa, C., L. Pacifico, F. Nanni, and G. Ravagnan. "Evaluation of Culture Techniques for GABHS." American Journal of Clinical Pathology 97, no. 1 (1992): 157–58. http://dx.doi.org/10.1093/ajcp/97.1.157.

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Kassem, Ahmed Samir, Salah R. Zaher, Hamida Abou Shleib, Abdel Ghany El-Kholy, Ahmed A. Madkour, and Edward L. Kaplan. "Rheumatic Fever Prophylaxis Using Benzathine Penicillin G (BPG): Two-week Versus Four-week Regimens: Comparison of Two Brands of BPG." Pediatrics 97, no. 6 (1996): 992–95. http://dx.doi.org/10.1542/peds.97.6.992.

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Objective. This prospective study was aimed at answering two important questions: 1) Is a biweekly schedule of 1.2 million U intramuscular benzathine penicillin G (BPG) superior to a 4-week one in the prevention of upper respiratory Group A beta-hemolytic streptococcal (GABHS) infections and rheumatic fever (RF) recurrences? 2) Is there a difference in the bioavailability of BPG obtained from different manufacturers? Methodology. Three hundred sixty rheumatic patients aged 4 to 20 years were randomly assigned to either a biweekly (190 patients) or 4-week (160 patients) BPG prophylactic schedul

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Pacifico, L., F. Scopetti, A. Ranucci, M. Pataracchia, F. Savignoni, and C. Chiesa. "Comparative efficacy and safety of 3-day azithromycin and 10-day penicillin V treatment of group A beta-hemolytic streptococcal pharyngitis in children." Antimicrobial Agents and Chemotherapy 40, no. 4 (1996): 1005–8. http://dx.doi.org/10.1128/aac.40.4.1005.

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The efficacy and safety of a 3-day course of azithromycin oral suspension (10 mg/kg of body weight once daily) were compared with those of penicillin V (50,000 U/kg/day in two divided doses) in children aged 3 to 12 years for the treatment of symptomatic pharyngitis caused by the group A beta-hemolytic streptococcus (GABHS). For the 154 evaluable patients, the original infecting strain of GABHS was eliminated at the end of follow-up (34 to 36 days after treatment started) from 67 (85.8%) of 78 penicillin-treated patients and 41 (53.9%) of 76 azithromycin-treated patients (P < 0.0001). Overa

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Malino, Imanuel Y., Dwi Lingga Utama та Yati Soenarto. "McIsaac criteria for diagnosis of acute group-A β-hemolytic streptococcal pharyngitis". Paediatrica Indonesiana 53, № 5 (2016): 258. http://dx.doi.org/10.14238/pi53.5.2013.258-63.

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Background The early use of antibiotics for acute upper respiratory infections is controversial because most of these infections are caused by viruses. A strategy is needed to correctly identify the causitive agents of acute pharyngitis, so that antibiotics can be prescribed appropriately.Objective To assess McIsaac criteria for diagnosing acute group-A β-hemolytic streptococcal (GABHS) pharyngitis in children.Methods This diagnostic study was conducted from August 2011 to February 2012, to compare clinical criteria of McIsaac to throat swab culture results as the gold standard for diagnosis.

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Davies, H. Dele. "Flesh-Eating Disease: A Note on Necrotizing Fasciitis." Canadian Journal of Infectious Diseases 12, no. 3 (2001): 136–40. http://dx.doi.org/10.1155/2001/857195.

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There has been much media attention in the past few years to the condition dubbed 'flesh-eating disease', which refers, primarily, to a form of invasive group A beta hemolytic streptococcal (GABHS) infection that leads to fascia and muscle necrosis. In 1999, the Canadian Paediatric Society issued a statement on the state of knowledge and management of children, and close contacts of persons with all-invasive GABHS disease (1). The present note is intended to deal specifically with necrotizing fasciitis (NF) by providing an update on the limited current state of knowledge, diagnosis and managem

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Gerber, Michael A., Martin F. Randolph, Nancy J. Martin, et al. "Community-wide Outbreak of Group G Streptococcal Pharyngitis." Pediatrics 87, no. 5 (1991): 598–603. http://dx.doi.org/10.1542/peds.87.5.598.

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Although several outbreaks of group G β-hemolytic streptococcal (GGBHS) pharyngitis have been described, doubt still remains regarding the etiologic role of GGBHS in acute pharyngitis beyond a limited number of situations. In the winter/spring of 1986/87, throat cultures were obtained from 222 consecutive children seen at a private pediatric office with acute pharyngitis and group A β-hemolytic streptococci (GABHS) were recovered from 91 children (41%) and GGBHS from 56 children (25%). One patient had both GABHS and GGBHS isolated. This isolation rate of GGBHS was dramatically greater than in

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Kıymaz, Meltem, Gülsüm Alkan, Büşra Özyalvaç, et al. "Infantile Intraparenchymal Brain Abscess due to Streptococcus pyogenes." Pediatric Practice and Research 12, no. 3 (2024): 83–87. http://dx.doi.org/10.21765/pprjournal.1531379.

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Introduction Group A ß-hemolytic streptococcus (GABHS) are the most common bacterial cause of tonsillitis, and can cause noninvasive diseases such as pharyngitis and impetigo, as well as more severe invasive diseases. The incidence of invasive disease is 1-3/100,000 per year, and the morbidity and mortality rate is high. GABHS is rarely lead to brain abscesses. Case Report Acute phase reactants were found to be high in a 40-day-old patient who presented with fever, irritability and focal seizures. Acute phase reactants were high. Transfontanel ultrasonography showed increased thickness, echo a

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DesRosiers, Annie, Patrick Dolcé, Philippe Jutras, and Louise P. Jetté. "Susceptibility of Group A Beta-Hemolytic Streptococci in the Lower St Lawrence Region, Quebec." Canadian Journal of Infectious Diseases 10, no. 4 (1999): 279–85. http://dx.doi.org/10.1155/1999/212549.

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OBJECTIVE: To determine the susceptibility of group A beta-hemolytic streptococci (GABHS) in the lower St Lawrence region, Quebec to different antibiotics, particularly macrolides, and to compare different antibiogram methods (disk diffusion, E-test and microdilution) and incubation atmospheres (ambient air and 5% carbon dioxide).METHODS: A total of 384 strains of GABHS isolated from 377 patients (throat 335; other sites 49) from three hospitals in the lower St Lawrence region were analyzed for their susceptibility to erythromycin, clarithromycin, azithromycin, penicillin, clindamycin, cephalo

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Gerber, Michael A., and Stanford T. Shulman. "Rapid Diagnosis of Pharyngitis Caused by Group A Streptococci." Clinical Microbiology Reviews 17, no. 3 (2004): 571–80. http://dx.doi.org/10.1128/cmr.17.3.571-580.2004.

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SUMMARY Although commercial rapid antigen detection tests (RADTs) are more expensive than blood agar plate (BAP) cultures, the advantage they offer is the speed with which they provide results. Rapid identification and consequent prompt treatment of patients with pharyngitis due to group A beta-hemolytic streptococci (GABHS) can reduce the risk of spread of GABHS, can allow patients to return to school or work sooner, and may reduce the acute morbidity of this illness. In most studies, RADTs have been compared with BAP cultures as the criterion standard. However, these comparisons are complica

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Needham, Cynthia A., Kenneth A. McPherson, and Kenneth H. Webb. "Streptococcal Pharyngitis: Impact of a High-Sensitivity Antigen Test on Physician Outcome." Journal of Clinical Microbiology 36, no. 12 (1998): 3468–73. http://dx.doi.org/10.1128/jcm.36.12.3468-3473.1998.

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The purpose of the present study was to determine whether the availability of results from a high-sensitivity, rapid test for group A streptococci (Strep A OIA; BioStar, Inc., Boulder, Colo.) improves physician outcome. The study population included 465 consecutive patients with symptoms of acute pharyngitis seen in two outpatient clinics in a large suburban medical center; one clinic, a walk-in clinic (WIC), primarily saw adult patients, and one clinic, a pediatric and adolescent medicine clinic (PED), primarily saw pediatric patients. We measured improvement in physician outcome by comparing

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Okumura, Rie, Sawako Yamazaki, Tsukasa Ohashi, et al. "Neuropsychiatric Disorder Associated with Group G Streptococcus Infection." Case Reports in Pediatrics 2018 (September 23, 2018): 1–3. http://dx.doi.org/10.1155/2018/6047318.

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Immune-mediated central nervous system manifestations of group A β-hemolytic Streptococcus (GABHS) infection include Sydenham’s chorea, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS)—which includes tic and obsessive compulsive disorders—and a variety of neurobehavioral disorders. We report a case of Streptococcus dysgalactiae subspecies equisimilis (group G Streptococcus) (GGS) infection associated with involuntary movements, complex tics, and emotional lability in an 11-year-old Japanese girl. Serum IgM and IgG antibodies to lysoganglioside we

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Merlini, Alexandre B., Carolina S. Stocco, Marcelo D. Schafranski, et al. "Prevalence of Group A Beta-Hemolytic Streptococcus Oropharyngeal Colonization in Children and Therapeutic Regimen Based on Antistreptolysin Levels: Data from a City From Southern Brazil." Open Rheumatology Journal 8, no. 1 (2014): 13–17. http://dx.doi.org/10.2174/1874312901408010013.

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The aim of this study is to determinate the prevalence of oropharyngeal colonization by group A beta-hemolytic Streptococcus (GABHS) in pediatric population of Ponta Grossa, a midsize city of southern Brazil; estimate the effectiveness of antistreptolysin-O (ASO), compared to culture, in presence of infection; and design an unpublished investigative algorithm of rheumatic fever's suspicion, based on needs identified in worldwide consensus. It is an epidemiologic, observational and transversal study, involving 180 children younger than 12 years. Secretion of posterior oropharynx was collected f

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Bakir, Saud Salim, Mohammed Zaki Salim Abdulridha, and Laith Mahmood Attallah. "Evaluation of the Effect of Tonsillectomy on Antistreptolysin O (ASO) Titer." Asian Journal of Medicine and Health 21, no. 11 (2023): 36–43. http://dx.doi.org/10.9734/ajmah/2023/v21i11917.

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Background: Acute recurrent tonsillitis is a common problem worldwide and tonsillectomy is the preferable treatment for patients not responding to medical treatment. Many patients with acute recurrent tonsillitis and increased antistreptolysin O (ASO) titers are caused by group A beta hemolytic streptococcal (GABHS) tonsillitis, which can lead to serious side effects such rheumatic fever and glomerulonephritis. ‎ Aim: To assess the consequence of tonsillectomy on ASO titer. Patients and Method: This prospective study was conducted to analyze the consequence of tonsillectomy on 43 p

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Saleem, Amer, and Marwan Faisal Buraa. "Effect of Tonsillectomy on Antistreptolysin O (ASO) Titer." Tikrit Journal of Pharmaceutical Sciences 17, no. 1 (2023): 22–29. http://dx.doi.org/10.25130/tjphs.2023.17.1.3.22.29.

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Abstract  Recurrent attacks of tonsillitis are a common worldwide problem and the best treatment of choice after failure of medical therapy is a tonsillectomy. The large numbers of patients that presented with recurrent attacks of tonsillitis and associated with high antistreptolysin O (ASO) titer level due to group A beta hemolytic streptococcal (GABHS) tonsillitis will have serious complications as glomerulonephritis and rheumatic fever. The aim of study: to evaluate the effect of tonsillectomy on elevated ASO titer. Patients and methods: Prospective non-randomized clinical study

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&NA;. "Five days?? erythromycin for children with GABHS infection?" Inpharma Weekly &NA;, no. 1065 (1996): 11. http://dx.doi.org/10.2165/00128413-199610650-00022.

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&NA;. "Should penicillin remain treatment of choice for GABHS?" Inpharma Weekly &NA;, no. 1447 (2004): 9. http://dx.doi.org/10.2165/00128413-200414470-00019.

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Kuhn, Susan M., Jutta Preiksaitis, Gregory J. Tyrrell, Taj Jadavji, Deirdre Church, and H. Dele Davies. "Evaluation of Potential Factors Contributing to Microbiological Treatment Failure inStreptococcus PyogenesPharyngitis." Canadian Journal of Infectious Diseases 12, no. 1 (2001): 33–39. http://dx.doi.org/10.1155/2001/297304.

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BACKGROUND:A cohort study of children with pharyngitis aged two to 16 years was conducted to assess the role of microbial and host factors in group A beta-hemolytic streptococcus (GABHS) microbiological treatment failure.METHODS:GABHS-infected children had pharyngeal swabs repeated two to five days after completing a 10-day course of penicillin V. M and T typing, and pulsed field gel electrophoresis were performed on the isolates, and the isolates were evaluated for tolerance. Patient characteristics and clinical features were noted and nasopharyngeal swabs for respiratory viruses were taken a

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&NA;. "Cefetamet pivoxyl: is comparable to phenoxymethylpenicillin for GABHS pharyngitis." Inpharma Weekly &NA;, no. 745 (1990): 7. http://dx.doi.org/10.2165/00128413-199007450-00017.

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Waldrep, Douglas Alan. "Two Cases Of ADHD Following GABHS Infection: A Pandas Subgroup?" Journal of the American Academy of Child & Adolescent Psychiatry 41, no. 11 (2002): 1273–74. http://dx.doi.org/10.1097/00004583-200211000-00008.

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