Journal articles: 'Gabonese Women'

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Althaus, F. "Chlamydia Plays a Major Role in Tubal Infections Leading to Ectopic Pregnancy in Gabonese Women." International Family Planning Perspectives 18, no. 3 (September 1992): 119. http://dx.doi.org/10.2307/2133413.

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Flügge, Judith, Ayôla Akim Adegnika, Yabo Josiane Honkpehedji, Thaisa L. Sandri, Esther Askani, Gédéon Prince Manouana, Marguerite Massinga Loembe, et al. "Impact of Helminth Infections during Pregnancy on Vaccine Immunogenicity in Gabonese Infants." Vaccines 8, no. 3 (July 11, 2020): 381. http://dx.doi.org/10.3390/vaccines8030381.

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Helminth infections are common in sub-Saharan Africa. Besides direct clinical effects, a bias towards a T helper type 2 (Th2) cell immune response is observed. The consequences of parasite infection during pregnancy for the mother and particularly for the fetus and the newborn can be severe and may include impaired immune response during acute infection and vaccination. Here, we present data of immune responses to vaccines given within the expanded program on immunization (EPI) of infants born to helminth infected or non-infected mothers. The study was conducted in Lambaréné and surroundings, Gabon. Maternal helminth infection was diagnosed microscopically using the Kato-Katz method for soil-transmitted helminths (STH), urine filtration for Schistosoma haematobium infections and the saponin-based method for filarial infections. Plasma antibody levels to different vaccine antigens were measured in mothers and their offspring by enzyme-linked immunosorbent assay (ELISA) at different timepoints. We found 42.3% of the mothers to be infected with at least one helminth species. Significantly lower anti-tetanus toxoid immunoglobulin (Ig) G was detected in the cord blood of infants born to helminth infected mothers. Following vaccination, immune responses of the infants to EPI vaccines were similar between the two groups at nine and 12 months. Even though infection with helminths is still common in pregnant women in Gabon, in our setting, there was no evidence seen for a substantial effect on infants’ immune responses to vaccines given as part of the EPI.

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Manego, Rella Zoleko, Eric Koehne, and Ghyslain Mombo-Ngoma. "PO 8563 UNCOMMONLY HIGH AND SYMPTOMATIC PLASMODIUM FALCIPARUM INFECTIONS IN GABONESE ADULTS." BMJ Global Health 4, Suppl 3 (April 2019): A53.3—A53. http://dx.doi.org/10.1136/bmjgh-2019-edc.140.

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BackgroundMalaria remains a public health issue particularly in sub-Saharan Africa with special features of seriousness in young children and pregnant women. Older children and adults reported to have acquired a semi-immune status and therefore show low parasitaemia and less pronounced symptoms if any. We aim to explore parasitaemia and symptoms in adolescents and adults with malaria compared to younger children in the Lambaréné area.MethodsWe conducted a cross-sectional study in CERMEL for a month in 2018. Adults and children were screened for malaria at health facilities in Lambaréné and Fougamou and their respective surrounding villages in the central region of Gabon. Malaria infection was determined either by rapid diagnostic test (RDT) or by thick blood smear (TBS). Body temperature, history of fever, age, sex, haemoglobin level, and location were collected.ResultsFrom 09 January to 09 February 2018, a total of 596 patients were screened and 280 (47%) belonged to the adult population. Plasmodium falciparum infection in adults was diagnosed based on the detection of P. falciparum in thick blood films. Prevalence among the adults was 56% (n=141); 34% of adult patients had a parasite count between 1015–116,079 pf/µl. Fever was found in 31% of adults and several symptoms were reported by the same patient. Vomiting, loss of appetite, and fatigue were significantly more present in the adult population than in children.ConclusionThis study shows a high rate of Plasmodium falciparum infection in adults associated to clinical symptoms and high level of parasitaemia. Adults seem to become an at-risk population, suggesting that malaria programmes should consider including adults in the implementation of a malaria prevention programme.

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Rich, Jeremy. "My Matrimonial Bureau: Masculine Concerns and Presbyterian Mission Evangelization in the Gabon Estuary, c. 1900-1915." Journal of Religion in Africa 36, no. 2 (2006): 200–223. http://dx.doi.org/10.1163/157006606777070669.

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AbstractThis essay examines the reasons why some young Fang men supported Presbyterian missionary Robert Milligan's crusade to establish a Protestant community of converts at the turn of the twentieth century. Milligan presented his work as an example of heroic and muscular Christianity that transformed young Gabonese men. However, his methods of attracting followers appear very similar to those used by local big men: creating kinship networks, providing military support, sharing imported goods and providing access to women for marriage. Fang men and Milligan shared a flexible vocabulary of fatherhood that placed obligations on converts and missionaries alike. Eventually, Milligan's efforts came undone because of problems with other missionaries, but young Fang men continued to turn to missionary patronage, in part to cope with gender tensions and struggles over status.

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Mayengue, Pembe Issamou, Horst Rieth, Ayman Khattab, Saadou Issifou, Peter G. Kremsner, Mo-Quen Klinkert, and Francine Ntoumi. "Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women." Tropical Medicine and International Health 9, no. 9 (September 2004): 949–58. http://dx.doi.org/10.1111/j.1365-3156.2004.01294.x.

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Mintsa-Ndong, Armel, Corneille Ndong-Ella, Roselyne K. Boussougou, Léatitia M. Busugu, Alexandre Mba, Franck A. Agwambouet, Nicolas Barro, and Joel F. Djoba Siawaya. "Mother-to-child HIV-transmission prevention programs in a sub-Saharan African setting: The Gabonese experience." International Journal of STD & AIDS 29, no. 3 (July 31, 2017): 221–26. http://dx.doi.org/10.1177/0956462417722132.

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In many developing countries, mothers’ awareness remains a challenge despite the scaling up of antenatal care and programs preventing mother-to-child (MTC) HIV transmission. The present study was done in Libreville, Gabon where all antenatal care (delivery included) is free of charge. Here we assessed the timing of antenatal antiretroviral (ARV) prophylaxis initiation, HIV-exposed infants’ age at their first postnatal HIV check visit and investigated the association between mothers’ awareness or knowledge on their ARV therapy and infants’ HIV infection. We interviewed HIV-positive mothers on their first and subsequent laboratory visits to investigate infants’ HIV status and tested infants for HIV RNA and antibody between 2012 and 2014. We established that (1) of 718 HIV-positive mothers, only 6% were fully aware and knew what ARV treatment they were on during pregnancy; (2) half of the women (54%) start their antenatal ARV prophylaxis initiation during the second trimester of pregnancy; (3) 64% of HIV-exposed infants had their first HIV infection screening between birth and three months of age; (4) the overall prevalence of HIV infection in infants born from infected mothers was 8.9%; and (5) infants born from mothers uncertain about taking prophylactic ARV therapy were 13.3 times more likely to be infected by HIV than infants born from mothers certain about taking prophylactic ARV therapy. In conclusion, the study showed that despite free antenatal care, early access and adherence to components of MTC, HIV transmission preventive care remains unsatisfactory.

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Bouyou-Akotet, Marielle Karine, Denise Patricia Mawili Mboumba, Eric Kendjo, Fanckie Mbadinga, Nestor Obiang-Bekale, Pacome Mouidi, and Maryvonne Kombila. "Anaemia and severe malarial anaemia burden in febrile Gabonese children: a nine-year health facility based survey." Journal of Infection in Developing Countries 7, no. 12 (December 15, 2013): 983–89. http://dx.doi.org/10.3855/jidc.3347.

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Introduction: Anaemia remains a major cause of poor health in children and pregnant women living in sub-Saharan Africa. Malaria is one of the main causes of anaemia in endemic countries. At the time of decreasing Plasmodium falciparum infection prevalence among children, it was essential to analyze the evolution of anaemia and severe malarial anaemia (SMA), the most frequent clinical manifestation of severe malaria, in Gabon. Methodology: Yearly recorded haemoglobin levels of febrile children aged below11 years, who benefitted from microscopic malaria diagnosis, were retrospectively analyzed to determine the evolution of anaemia and SMA prevalence throughout a nine-year period between 2000 and 2008. Results: Anaemia prevalence remained high both in P. falciparum-infected children (between 87.6% and 90.7%) and in uninfected children (between 73.5% and 82.6%). Although the risk of developing severe anaemia ranged between 1.9 [0.9-3.8] in 2000 and 3.0 [1.3-6.5] in 2007, SMA prevalence did not significantly change during the study period, varying from 6.0% to 8.0%. From 2001, the frequency of SMA was comparable between children younger than five years of age and children older than five years of age. Conclusions: The decreasing malaria prevalence previously observed in Gabon between 2000 and 2008 was not associated with a significant reduction of anaemia and SMA burden among children. Furthermore, other factors such as nutritional deficiencies, which may not be negligible, must be investigated in this vulnerable population

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Fungo, Robert, John Muyonga, Judith Ngondi, Christian Mikolo-Yobo, Donald Iponga, Alfred Ngoye, Erasmus Nchuaji Tang, and Julius Chupezi Tieguhong. "Nutrient and Bioactive Composition of Five Gabonese Forest Fruits and Their Potential Contribution to Dietary Reference Intakes of Children Aged 1–3 Years and Women Aged 19–60 Years." Forests 10, no. 2 (January 23, 2019): 86. http://dx.doi.org/10.3390/f10020086.

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Widely consumed forest fruits in Gabon were analysed for nutrient and bioactive compositions and their potential contributions to meeting the nutrient requirements of consumers. Edible pulps of Panda oleosa Pierre, Gambeya lacourtiana (De Wild.) Aubrév. & Pellegr. and Poga oleosa Pierre contained substantial amounts of bioactive compounds; flavonoids (13.5–22.8 mg/100 g), proanthocyanins (2.4–7.6 mg/100 g), polyphenols (49.6–77.3 mg/100 g) and vitamin C (6.7–97.7 mg/100 g). The highest content of β-carotene (76.6 µg/100 g) was registered in fruits of Pseudospondias longifolia Engl. The fruits of P. oleosa had the highest essential minerals Fe, Zn and Se. If a child aged 1 to 3 years consumed about 200 g or if a non-lactating and non-pregnant woman consumed 300 g of Panda oleosa, Afrostyrax lepidophyllus Mildbr., G. lacourtiana, P. longifolia and Poga oleosa, they could obtain substantial DRI ranging between 20–100% for energy, vitamins C and E, iron, magnesium, iron and zinc. Forest fruits can considerably contribute towards the human nutrient requirements. Based on the results of this study, forest foods should be considered in formulating policies governing food and nutrition security in Gabon.

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Grobusch, Martin P., Steffen Borrmann, Justin Omva, Saadou Issifou, and Peter G. Kremsner. "Severe malaria in a splenectomised Gabonese woman." Wiener Klinische Wochenschrift 115, no. 1-2 (January 2003): 63–65. http://dx.doi.org/10.1007/bf03040275.

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10

Ondounda, M., S. Pither Antchoue, and C. Zamba. "Giant anogenital condyloma in an HIV-infected Gabonese woman." Médecine et Santé Tropicales 22, no. 1 (January 2012): 12. http://dx.doi.org/10.1684/mst.2012.0019.

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11

GRAY, CHRISTOPHER, and FRANÇOIS NGOLET. "LAMBARÉNÉ, OKOUMÉ AND THE TRANSFORMATION OF LABOR ALONG THE MIDDLE OGOOUÉ (GABON), 1870–1945." Journal of African History 40, no. 1 (March 1999): 87–107. http://dx.doi.org/10.1017/s0021853798007361.

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IN 1929, the French colonial administration's forced recruitment of labor for two road construction projects designed to create more effective transportation links between the town of Lambaréné on the Middle Ogooué and the colonial post at Mouila on the Upper Ngounié led to food shortages in several parts of southern Gabon. A disturbing pattern had developed over the previous 15 years where colonial demands for labor led to disruptions in the seasonal cycle of agricultural production. Able-bodied men forced to gather forest products or work as porters to pay the head tax, or required to participate in the construction of colonial infrastructure projects, or even willingly employed as laborers in the growing timber industry, could not meet their traditional obligations to clear fields for women farmers during the long dry season (generally June to September), thus leading to poor harvests and food shortages. French officials at the end of the 1920s were especially anxious as the Fang populations in the northern portion of the colony had experienced severe famine several years earlier, partly due to male workers being recruited into the timber industry. Memories of famine occurring between 1916 and 1918 were also quite vivid among the peoples living along the Ngounié. Labor recruitment for the timber industry and colonial infrastructure projects remained a precarious enterprise at the outset of the 1930s. Yet by the 1940s, the most difficult segment of the Lambaréné–Mouila road network – a 50 kilometer stretch through hilly, forested terrain south of Lambaréné – was completed without resorting to forced labor and without the threat of food shortages. The intervening decade had witnessed the final stage of the transformation of Gabonese labor wrought by the French colonial presence, a transformation that broke the pre-colonial system of labor exploitation controlled by clan leaders. At the outbreak of World War II, the process had advanced to the point that there now existed a ‘labor market’ in the French Equatorial Africa federation integrated into the capitalist wage-earning sector and capable of accomplishing infrastructure projects without disastrous consequences for the local population. We argue that the predominance of the timber industry in Gabon placed these developments on a strangely ambiguous path when compared to the growth of capitalist wage-labor in other parts of the continent.

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Mbadinga, Samuel. "Puerperal Pregnancy Psychopathology: The Psychic Space of Unsafe Abortion in a Gabonese Woman." Psychology and Behavioral Sciences 7, no. 5 (2018): 82. http://dx.doi.org/10.11648/j.pbs.20180705.11.

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Ludwig, Esther, Jutta Harder, Matthew Lacorcia, Yabo Josiane Honkpehedji, Odilon Paterne Nouatin, Govert J. van Dam, Paul L. A. M. Corstjens, et al. "Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country." Scientific Reports 9, no. 1 (October 31, 2019). http://dx.doi.org/10.1038/s41598-019-52074-z.

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Abstract In utero exposure to environmental factors can modify the development of allergies later in life whereby the mechanisms of the feto-maternal crosstalk still remain largely unknown. Murine studies revealed that inflammatory maternal signals elicited by chronic helminth infection within the placenta imprint a distinct gene expression profile related to the Vitamin-D-receptor (VDR)-inflammation-axis. We thus investigated whether pro- or anti- inflammatory immune responses as well as VDR and related gene expression within the placenta differ between women from helminth-endemic and non-endemic areas. A prospective pilot study was conducted in Munich, Germany (helminth non-endemic) and Lambaréné, Gabon (helminth-endemic). At delivery, clinical information alongside placenta tissue samples and maternal and cord blood were obtained for further laboratory analysis. Schistosoma haematobium infection was detected in 13/54 (23%) Gabonese women. RT PCR revealed significantly lower gene expression of VDR, Cyp27b1, Foxp3 and IL10 in Gabonese compared to German placentae as well as significantly lower levels of plasma IgG4 in newborns resulting in a significantly higher IgE/IgG4 ratio. These findings demonstrate that exposure in utero to different environments alters placental gene expression and thus possibly plays a role in the development and modulation of the immune system of the offspring.

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Zoa Assoumou, Samira, Angelique Ndjoyi Mbiguino, Barthelemy Mabika Mabika, Sidonie Nguizi Ogoula, Mohammed El Mzibri, Abdelkrim Khattabi, and My Mustapha Ennaji. "Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities." Infectious Agents and Cancer 11, no. 1 (January 15, 2016). http://dx.doi.org/10.1186/s13027-016-0046-0.

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Mangala, Christian, Therese Nkoa, Denis Maulot-Bangola, Franck Vivien Vigan Codjo, and Joseph Fokam. "Seroprevalence and Risk Factors Associated with Human Immunodeficiency Virus Infection Type 1 in Donors of the National Blood Transfusion Center of Libreville (Gabon)." International STD Research & Reviews, May 22, 2021, 16–24. http://dx.doi.org/10.9734/isrr/2021/v10i230128.

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Background: Transmission of HIV through blood transfusion remains a public health problem, particularly in countries in Sub-Saharan Africa. However, no study has determined the epidemiological data regarding HIV-1 infection in Gabonese blood donors. The objective of this study is to assess the seroprevalence of HIV-1 and the risk factors associated with infection in donors from the National Blood Transfusion Center in Libreville (Gabon). Methods: A cross-sectional study carried out from June to August 2020 in 3669 persons donating blood at the National Blood Transfusion Center (NBTC). The ELISA technique (Evolis®, BioRad), the chemiluminescence technique (Cobas® e601, Roche), and the SD Bioline® HIV 1/2 test (Standard Diagnostics. Inc) were used for the detection of anti-HIV-1/2 antibodies and P24 antigen in donor plasma. Data were analyzed using SPSS software version 21.0, with p˂.05 considered statistically significant. Results: The seropositivity rate HIV-1 was 0.8% (30/3669) (95% CI: 0.5; 1.1). The study was composed of 79.4% men and 20.6% women. The most representative age group was of 25-34 years with 54.5%. The seropositivity of men, women, and unrelated voluntary donors was 0.7%, 1.2%, and 1.0%, respectively. The risk factors such as the first blood donation (Adjusted Odds Ratio (AOR) = 0.1 [0.0 ;0.4], P= .002), multiple sexual partners (AOR = 6.2 [2.2;17.2], P= .001), primary educational level (AOR = 10.1 [1.4;75], P = .024), and dental care (AOR = 3.6 [1.2;11], P = .024) were significantly associated with HIV infection. About 0.14% of the patients had co-infection. Conclusion: In the Gabonese context, about one out of a hundred blood donors are HIV-infected. These carriers of HIV infection in the blood banks are mainly new donors with multiple sexual partners, limited education, and poor dental care.

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Assoumou, Samira Zoa, Anicet Luc M. Boumba, Angelique Ndjoyi-Mbiguino, Abdelkrim Khattabi, and Moulay Mustapha Ennaji. "The preliminary study of p53 codon 72 polymorphism and risk of cervical carcinoma in Gabonese women." Medical Oncology 32, no. 1 (December 12, 2014). http://dx.doi.org/10.1007/s12032-014-0281-4.

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Bouyou-Akotet, Marielle K., Marie-Louise Tshibola, Denise P. Mawili-Mboumba, Julie Nzong, Noemi Bahamontes-Rosa, Gladys Tsoumbou-Bakana, and Maryvonne Kombila. "Frequencies of dhfr/dhps multiple mutations and Plasmodium falciparum submicroscopic gametocyte carriage in Gabonese pregnant women following IPTp-SP implementation." Acta Parasitologica 60, no. 2 (January 1, 2015). http://dx.doi.org/10.1515/ap-2015-0031.

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AbstractThis study analyzed the relationship between intermittent preventive treatment with sulfadoxine-pyrimethamine (SP) (IPTp-SP), the rate of multiple resistant parasites and of submicroscopic gametocyte carriage among pregnant women at the beginning of IPTp implementation in Gabon (2005) and six years after (2011). The detection of pfdhfr and pfdhps gene mutations was performed by PCR-RFLP in Plasmodium (P.) falciparum positive samples collected from pregnant women in 2005 and 2011. Gametocytes carriage was detected by Pfs25mRNA amplification using QT-NASBA. Data were analyzed according to the time of collection (study period) and IPTp-SP doses. The proportion of isolates with at least a triple Pfdhfr mutation (n = 39/42, 92.9% versus 100%, n = 78/78)) and of those isolates with the S108N/C59R/N51I/S436A/A437G multiple mutation (17.9% versus 75.6%) significantly increased between 2005 and 2011 (p<0.01). Mutations I164L and A581G were not found, while higher proportions of 436 and 437 mutations were detected in 2011.A trend toward a higher frequency of isolates with five mutations was observed in women who received two SP doses (p<0.01). Pfs25mRNA was found in 6.8 % (n = 3/44) and 34.6% (n = 27/78) of the samples collected in 2005 and 2011 respectively (p<0.01). In 2011, 74.0% (n = 20/27) of women with detected submicroscopic gametocytes carried parasites with the S108N/C59R/N51/S436A/A437G multiple mutation. All the ten delivering women who received three IPTp-SP doses had a submicroscopic Plasmodium falciparum infection, but none had detected gametocytes. Following IPTp-SP implementation, an increase in the frequency of multiple mutant parasites and of submicroscopic gametocyte carriage was observed among pregnant women living in Gabon.

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"Study of the Glycemic Control and the Biochemical Profile in the Gabonese Diabetic Patient." International Journal of Diabetes & Metabolic Disorders 2, no. 1 (June 30, 2017). http://dx.doi.org/10.33140/ijdmd/02/01/00002.

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Background: Management of diabetes remains a challenge in Africa. Objective: The aim of this study was to evaluate the glycemic control in diabetics patients with diabetes in Gabon sub-Saharan country. Methods: This study involving 87 diabetic patients (Men25 ; Women : 62) were investigated anthropometric parametres, glycemic control and biochemical profil. Results: All our results show that with an average age of 53±11.02 years diabetic Gabonese patients present a poor glycemic control (P <0.0001): Glycemia (Control: 4.95 ± 1.16 mmol/l vs Diabetic : 10.27 ± 4.47 mmol/l) ; HbA1c (Control : 5.05 ± 0.46% vs Diabetics : 7.40 ± 2.36%) associated with a hepatic steatosis : Alat ( Alat : Control: 17.25 ± 13.7u/l vs Diabetic: 25.84 ± 13.19 u/l), Asat (Control: 18 ± 13.20 u/l vs Diabetic: 36.93 ± 17.87 u/l). Conclusion: Is evidence, a high proportion of patients with diabetes remains poorly controlled. This is the case in Gabon diabetic patients.

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Assoumou, Samira Zoa, Barthelemy Mabika Mabika, Angelique Ndjoyi Mbiguino, Mustapha Mouallif, Abdelkim Khattabi, and My Mustapha Ennaji. "Awareness and knowledge regarding of cervical cancer, Pap smear screening and human papillomavirus infection in Gabonese women." BMC Women's Health 15, no. 1 (April 19, 2015). http://dx.doi.org/10.1186/s12905-015-0193-2.

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Sanogo, N’doh Ashken, Arone Wondwossen Fantaye, and Sanni Yaya. "Beyond coverage: a qualitative study exploring the perceived impact of Gabon’s health insurance plan on access to and quality of prenatal care." BMC Health Services Research 20, no. 1 (May 30, 2020). http://dx.doi.org/10.1186/s12913-020-05310-6.

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Abstract Background Access to affordable and adequate healthcare in a health system determines the universal health coverage achievement for all residents in a country. Achieving access to healthcare requires the availability of a financing system that ensures access to and provision of adequate care, regardless of the ability to pay. In sub-Saharan Africa, accessibility, use and coverage of prenatal visits are very low and poor, which reduces the quality of care. This paper explored the impact of a social health insurance scheme on the quality of antenatal care in Gabon. Methods This qualitative study involved the analysis of data collected from semi-structured interviews and non-participant observations to assess the quality of antenatal care. The study elicited perceptions on the demand side (pregnant women) and the supply side (health professionals) in health facilities. Fifteen semi-structured interviews were conducted with pregnant women (aged between 15 and 49) and 5 with health professionals, who each had a seniority of at least 10 years, at different levels of care. Nine non-participant observations were also conducted. Coded transcripts were reviewed and analyzed using the Canadian Institute for Public Administration of Citizen-Centered Services model as an analytical guide. Results On the demand side, women were generally satisfied with the prenatal services they receive in health facilities. However, complaints were made about the rudeness of some nurses, the high price of the delivery kit (50,000 XAF), and the fact that some essential medicines for maternity are not covered. On the supply side, participants agreed that compulsory health insurance is important in providing antenatal care access to those who need it the most. However, some problems remain. The participants outlined some logistical problems and a lack of medical equipment, including the stock of drugs, disinfectants, and the absence of clean water. Conclusion Understanding the perceptions of pregnant women and health professionals regarding the quality of antenatal care can help to inform refinements to methods through which the services can be better provided. In addition, the study findings are vital to increasing the use of care, as well as combating high maternal mortality rates. Compulsory health insurance has improved the accessibility and utilization of healthcare services and has contributed to improved quality of care.

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Journal articles on the topic 'Gabonese Women'

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