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Dissertations / Theses on the topic 'Gait in animals Research'

Author: Grafiati

Published: 10 December 2022

Last updated: 31 July 2025

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1

Chadwick, Wayne. "Observed metabolic changes in male Wistar rats after treatment with an antidepressant implied in undesirable weight gain, or Sutherlandia frutescens for Type II diabetes." Thesis, University of Port Elizabeth, 2003. http://hdl.handle.net/10948/313.

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Type II diabetes is fast becoming a growing problem in developed countries worldwide. Traditionally the median age for diagnosis was around sixty, but recent surveys have shown that the entire age distribution curve has shifted to the left. Western countries boast the worst statistics in which type II diabetes is being reported in children under the age of ten. At such a young age the disease often goes undiagnosed for long periods of time allowing considerable damage to occur. The incidence of type II diabetes is thought to be parallel with the growing rate of obesity associated with a charac

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2

Wills, Eric David. "Gait animation and analysis for biomechanically-articulated skeletons /." Connect to title online (Scholars' Bank) Connect to title online (ProQuest), 2008. http://hdl.handle.net/1794/7508.

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Thesis (Ph. D.)--University of Oregon, 2008.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 281-287). Also available online in Scholars' Bank; and in ProQuest, free to University of Oregon users.

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3

Kurek, Justin, and University of Lethbridge Faculty of Arts and Science. "Deficits of gait initiation and steady state gait are exacerbated by postural threat in Parkinson's disease patients." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2005, 2005. http://hdl.handle.net/10133/667.

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The effects of postural threat on gait initiation and steady state gait among Parkinson’s disease (PD) patients and age-matched adults were examined. Ten healthy adults (CTRL; mean age= 68.8 ± 8.4, range 56-80 years) and ten PD patients (PDOFF / ON ; mean age= 69.7 ± 10.3, range 54-81 years) initiated gait and continued with steady state walking along a walkway of two different height conditions. PD patients were first tested in a non-medicated state followed by testing in a medicated state. The results showed that gait initiation and steady state gait deficits inherent to PD are exacerbated i

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4

Malavé, Laura Helena. "Silhouette based gait recognition research resource and limits /." [Tampa, Fla.] : University of South Florida, 2003. http://purl.fcla.edu/fcla/etd/SFE0000059.

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5

Malavé, Laura Helena. "Silhouette based Gait Recognition: Research Resource and Limits." Scholar Commons, 2003. https://scholarcommons.usf.edu/etd/1423.

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As is seen from the work on gait recognition, there is a de-facto consensus about the silhouette of a person being the low-level representation of choice. It has been hypothesized that the performance degradation that is observed when one compares sequences taken on different surfaces, hence against different backgrounds, or when one considers outdoor sequences is due to the low silhouette quality and its variation. If only one can get better silhouettes the perfomance of gait recognition would be high. This thesis challenges that hypothesis. In the context of the HumanID Gait Challenge proble

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6

Low, Lesley Ann. "Stability of coupled van der pol oscillators and applications to gait control in simple animals /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/7096.

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7

Wills, Eric David 1977. "Gait animation and analysis for biomechanically-articulated skeletons." Thesis, University of Oregon, 2008. http://hdl.handle.net/1794/7508.

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xx, 287 p. ; ill. (some col.) A print copy of this title is available through the UO Libraries under the call numbers: SCIENCE QP310.W3 W55 2008<br>Digital three-dimensional (3D) models are useful for biomechanical analysis because they can be interactively visualized and manipulated. Synthesizing and analyzing animal locomotion with these models, however, is difficult due to the large number of joints in a fully articulated skeleton, the complexity of the individual joints, and the huge space of possible configurations, or poses, of the skeleton taken as a whole. A joint may be capable of

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Schuessler, Thomas F. "A computer controlled research ventilator for small animals /." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69704.

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Understanding the mechanical properties of the respiratory system is an important task in pulmonary physiology. Current research often involves small mammals (mice, rats or guinea pigs) which are easily obtained in large numbers as pure bred strains, thus allowing statistically reliable results with minimal inter-animal variation to be obtained. However, due to the small flow amplitudes involved, the input impedance of common flow measurement devices is often too low to reliably measure tracheal flow. Furthermore, experimental setups are usually very limited in the types of volume, pressure or

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9

Siegel, Angeline M. "Unspoken connections| Scientists' intersubjective experiences with animals." Thesis, Saybrook University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3711355.

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<p> Little is known about the scientist-animal relationship; therefore, the aim of this study was to learn how moments of intersubjectivity, or "oneness" are created and experienced by scientists. It is by appreciating the risks and vulnerabilities intrinsic to human-animal relationships that propel the present investigation. The current cultural bias of valuing objectification and detachment as the predominant form of scientific investigation overlooks relational subtleties intrinsic to deriving meaning from humananimal studies. By examining scientists and their descriptions of intersubjectiv

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10

Lee, Dong Gil. "Relationship between arch height and midfoot joint pressures during gait." Cleveland, Ohio : Cleveland State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1227563948.

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Thesis (D. Eng.)--Cleveland State University, 2008.<br>Abstract. Title from PDF t.p. (viewed on Feb. 2, 2009). Includes bibliographical references. Available online via the OhioLINK ETD Center. Also available in print.

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11

D'Angelo, Maurissa S. "Analysis of Amputee Gait using Virtual Reality Rehabilitation Techniques." Wright State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=wright1279121086.

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12

Ali, Cairo F. "Animal rights and animal research." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1371556393.

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13

Layton, Raymond J. "Macroinvertebrate colonization and production in new experimental ponds." Diss., This resource online, 1989. http://scholar.lib.vt.edu/theses/available/etd-03042009-040552/.

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14

Oberhofer, Katja. "Anatomically-based, subject-specific modelling of lower limb motion during gait." Thesis, University of Auckland, 2009. http://hdl.handle.net/2292/5444.

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15

Melonas, Alexander Paul. "Situated Animals: A Critique of Social Constructivist Excesses in Political Theory." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/321722.

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Political Science<br>Ph.D.<br>In this dissertation I explore the ramifications of political theory being freed from two opposed extremes of biologism and social constructivism because, ultimately, the human animal is both a biological creature and capable of becoming. While it has been highly significant for humanistic scholars to challenge the governing authority of the "hard sciences" as the prime site of legitimacy in modern scholarship, the position of critique has transformed into one of outright and unqualified hostility. I resist this commitment to show that work at the intersection of

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16

Maslivec, Amy. "Age related changes in the mechanisms contributing to head stabilisation, and whole body stability during steady state gait and gait initiation." Thesis, University of Cumbria, 2018. http://insight.cumbria.ac.uk/id/eprint/3752/.

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Head stabilisation during gait related tasks is thought to be fundamental to whole body stability, but this has received little attention in the older population. There is a need to examine any age related changes in neuromechanical mechanisms underpinning head stabilisation that may challenge the control of head stability, and consequently whole body stability. The present Thesis examined the mechanisms contributing to head stabilisation, and whole body stability during two gait tasks, steady state gait and gait initiation in young and older females, with the overall aim of contributing to ne

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17

Hamilton, Kristin Marie. "Benefits of Community Research-Based Programming to Improve Freezing of Gait for Individuals with Parkinson Disease." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/297620.

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For one week, six subjects with Parkinson Disease (PD) attended a boot camp at the Parkinson Wellness Recovery (PWR!) Gym. Each experienced a unique symptom of PD known as freezing of gait (FOG). Previous research supports task-specific exercise for improving PD symptoms; this study focuses on task-specific exercise to reduce FOG. Reducing the severity of hypokinetic and bradykinetic movement was addressed during the week through large amplitude training that was integrated into interval training during cardiovascular exercise, agility and postural control exercises, and real world environment

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18

Hines, Dustin J., and University of Lethbridge Faculty of Arts and Science. "The role of cues and the hippocampus in home base behaviour." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2004, 2004. http://hdl.handle.net/10133/646.

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The thesis examines the ability of animals to construct a home base. The home base is a point in space where animals rear, groom, and circle and is a primary element in organized spatial behaviour (Eilam and Golani 1989). Once animals establish a home base, they make outward trips and stops, and after a series of trips and stops they return again to the home base. The home base behaviour of animals acts as a platform for asking questions about the cognitive organization of an environment. The thesis describes five main findings. Control and hippocampectomized animals use (1) proximal and (2) d

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19

Poddar, Darshana Ph D. "Study of Role of Ribosomal Protein L13a in Resolving Inflammation." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1400587453.

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20

Bagchi, Tamishraha. "Immune mechanisms in murine brucellosis : studies with strain RB51, a rough mutant of Brucella abortus /." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-09162005-115020/.

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21

Himmler, Brett T., and University of Lethbridge Faculty of Arts and Science. "The effect of playful experiences on the plasticity and metaplasticity of the brain." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, 2011, 2011. http://hdl.handle.net/10133/3081.

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The influence of play behavior on the brain was investigated through plasticity and metaplasticity methodology. Regions in both cortical and sub-cortical areas were investigated. Animals in both studies either experienced play with juvenile partners or did not experience play by being paired with an adult. Play experience alone was shown to affect the plasticity in the prefrontal cortex, although it did not show structural changes to sub-cortical regions. If animals were given nicotine after play experiences, the affects of play in the prefrontal cortex were abolished. In addition, playful beh

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22

Fang, Yu-Hua. "Quantification of Pharmacokinetics in Small Animals with Molecular Imaging and Compartment Modeling Analysis." Cleveland, Ohio : Case Western Reserve University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1238635584.

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Thesis (Ph.D.)--Case Western Reserve University, 2009<br>Department of Biomedical Engineering Abstract Title from OhioLINK abstract screen (viewed on 10 April 2009) Available online via the OhioLINK ETD Center

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23

Lyons, Daniel Louis. "Protecting animals versus the pursuit of knowledge : the evolution of the British animal research policy network." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434527.

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24

Bolstad, K. S. "Systematics of the Onychoteuthidae Gray, 1847 (Cephalopoda: Oegopsida) a thesis submitted to the Earth & Oceanic Sciences Research Institute, Auckland University of Technology in fulfilment of the requirements for the degree of Doctor of Philosophy, supervised by Dr Steve O'Shea, 2008." Click here to access this resource online, 2008. http://hdl.handle.net/10292/414.

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25

Germain, P. "HUMANS, ANIMALS, AND PETRI DISHES: BIOMEDICAL MODELING BETWEEN EXPERIMENTATION AND REPRESENTATION." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/234133.

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The use and evaluation of biomedical models – in vitro and in vivo models of diseases – is discussed among scientists, philosophers and science policy-makers, in an attempt to maximize the efficiency and relevance of research and minimize unnecessary moral costs. However, such evaluations raise several methodological issues and have generally been hampered by a lack of attention to the precise functions played by biomedical models. For if biomedical models are ultimately expected to inform us about human pathologies, they seldom do so in isolation, and get there through a wide variety of ways.

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26

Lowings, Michael D., and University of Lethbridge Faculty of Arts and Science. "Epigenetic regulation of stroke recovery : changes in DNA methylation and micro-RNA regulation following stroke and EGF/EPO neurogenesis therapy." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2010, 2010. http://hdl.handle.net/10133/2570.

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Stroke is one of the most common, and damaging, neurological afflictions. Stroke causes widespread and variable chronic effects, due to the limited regenerative ability of the adult brain. Altered gene expression induces neuronal changes necessary for plasticity-dependent recovery, effects which can be enhanced by growth hormone-based pharmaceuticals. These processes are driven by alterations in the informational capacity of the genome – changes driven by epigenetic regulators. Following experimental strokes, and treatment with EGF and EPO, this study shows that two epigenetic regulator

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27

Molina, Leonardo A. "Alteration of neural dynamics in the rat medial prefrontal cortex by an NMDA antagonist." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2012, 2012. http://hdl.handle.net/10133/3264.

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NMDA receptor antagonists such as Ketamine and PCP are potent psychoactive drugs used recreationally. This class of drug induces a number of phenomena in humans similar to those associated with schizophrenia including reduced selective attention, altered working memory, thought disorders and hallucinations. These psychotomimetic drugs have thus been used as a longstanding model to study this disease in animals. Importantly, such animal models allow for recording of brain activity using invasive techniques that are inappropriate in humans. Previous electrophysiological studies have shown that M

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Clark, Callie Anne Marie, and University of Lethbridge Faculty of Arts and Science. "Sound-induced behavioural activation in the normal and haloperidol-treated rat." Thesis, Lethbridge, Alta. : University of Lethbridge, Canadian Centre for Behavioural Neuroscience , c2008, 2008. http://hdl.handle.net/10133/1293.

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Diseases of the central and peripheral nervous systems affect one in five people in North America. Parkinson’s disease (PD) is the second most common neurodegenerative disease, after Alzheimer’s disease, and occurs in approximately 1% of the general North American population. PD is a progressive movement disorder that is characterized by resting tremor, rigidity, bradykinesia (slowness of movement) or akinesia (absence of spontaneous movement), as well as postural instability. Current treatment of PD is symptom-based, and no pharmacological treatment currently exists to slow the progression of

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29

Zelinski, Erin L., and University of Lethbridge Faculty of Arts and Science. "Impacts of chronic and acute phase-shifting in male and female rats." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2010, 2010. http://hdl.handle.net/10133/2590.

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This thesis assessed the impacts of acute and chronic phase-shifting on learning and memory in male and female rats. Previous research has revealed impaired retention immediately following circadian disruption and on the acquisition of new associations. However, whether behaviour resumes normality following circadian re-entrainment is unresolved. Following circadian re-entrainment, retention of pre-phase-shift acquired associations on Morris water task (MWT) and a visual discrimination task designed on the 8-arm radial maze were tested. Subsequently, an extradimensional set shift (EDS) using t

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Hardy, Jared C., and University of Lethbridge Faculty of Arts and Science. "Behavioral correlates of unilateral dopamine depletion in the MPP+ rat model of Parkinson's Disease." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007, 2007. http://hdl.handle.net/10133/385.

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Conventional cylinder test measures have limited sensitivity in determining hemiparkinson rat forelimb use asymmetry and approximating substantia nigra (SN) dopaminergic neuron loss. This thesis investigates which cylinder test measures of hemiparkinson rat forelimb use asymmetry best predict methamphetamine-induced rotation and extent of dopaminergic neuron loss. Long-Evans rats were cylinder-tested after unilateral 1-methyl-4-phenylpyridinium (MPP+)-induced SN dopamine depletion. Time and count of numerous forepaw wall contact patterns were documented for MPP+ hemiparkinson rats and sham-ope

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31

Frede, David. "A tale of two zoos : a study in watching people watching animals." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/3762.

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Zoological gardens, or zoos, keep and display wild animals, mainly for the purposes of education, conservation and biological research. However, it is evident that a significant component of zoos is the vast number of people who visit them, since without the support of visitors, zoos would not be financially viable and would cease to exist. This research investigates the behaviours of these visitors and develops an understanding of their awareness relating to what they see and do while they are in the zoo, along with their motivations for visiting. The study focuses on two major metropolitan z

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Frede, David. "A tale of two zoos : a study in watching people watching animals." University of Sydney, 2007. http://hdl.handle.net/2123/3762.

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Doctor of Philosophy<br>Zoological gardens, or zoos, keep and display wild animals, mainly for the purposes of education, conservation and biological research. However, it is evident that a significant component of zoos is the vast number of people who visit them, since without the support of visitors, zoos would not be financially viable and would cease to exist. This research investigates the behaviours of these visitors and develops an understanding of their awareness relating to what they see and do while they are in the zoo, along with their motivations for visiting. The study focuses on

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33

Driscoll, Ira, and University of Lethbridge Faculty of Arts and Science. "The aging hippocampus : a multilevel analysis in the rat." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2005, 2005. http://hdl.handle.net/10133/12.

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The purpose of the current thesis was twofold: (1) to examine various factors that might be contributing to age-related learning and memory deficits specifically related to the hippocampus, and (2) to validate our rat model of aging, employing a multilevel analysis. We found age-related deficits on both spatial and non-spatial hippocampus-dependent taks that were accompanied by structural alterations observed in vivo (volune, but not neuronal metabolic function) and post mortem (neuronal density and neurogenesis, but not synaptic or mitochondrial density). Furthermore, our results suggest th

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34

Sparks, Fraser T. "Interactions of the hippocampus and non-hippocampal long-term memory systems during learning, remembering, and over time." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2012, 2012. http://hdl.handle.net/10133/3116.

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The hippocampus and non-hippocampal long-term memory systems each have the capacity to learn and express contextual fear memory. How these systems interact during learning and remembering revolves around hippocampal mediated interference, where the hippocampus dominates for both the acquisition and expression of long-term memory. Hippocampal interference during learning can be overcome by modifying learning parameters such that learning is distributed across multiple independent sessions. The standard view of the role of the hippocampus in long-term memory retrieval is that it is temporally li

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35

Botha, Hermanus Van Niekerk. "A Closed Loop Research Platform That Enables Dynamic Control Of Wing Gait Patterns In A Vertically Constrained Flapping Wing - Micro Air Vehicle." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1462801627.

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36

Messer, Alicia B. "Short-Term Benefits of Research-Based, Task-Specific Exercises in a Group Setting for People with Parkinson Disease and Freezing of Gait." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/311799.

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37

Lombard, Chereé. "Animal welfare and the law : towards legal regulation of the welfare of laboratory animals in South Africa / Chereé Lombard." Thesis, North-West University, 2012. http://hdl.handle.net/10394/8718.

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The current legal framework pertaining to animals does not sufficiently address the welfare of animals. The Animal Protection Act 71 of 1962 does not specifically regulate the welfare of animals contained in research laboratories. Animals utilized for experimental research purposes endure tremendous “unnecessary suffering” due to legislative inaptitude. Experimental animals suffer inherent abuses associated with experimental research because of the methods, procedures and processes relevant to the experiments. The most controversial method of experimental research is vivisection. The method of

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38

Dutta, Anirban. "Development of an Electromyogram-Based Controller for Functional Electrical Stimulation-Assisted Walking After Partial Paralysis." Cleveland, Ohio : Case Western Reserve University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1238761874.

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Liu, Xingbo. "Cardiac Calcium Channel Expression in Heart Specific Growth Hormone (GH) Receptor Gene Disrupted Mice and Bovine GH Mice." Ohio University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1397650862.

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Cardiff, James W. "Experienced-induced immediate early gene expression in hippocampus after granule cell loss." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2012, 2012. http://hdl.handle.net/10133/3356.

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Adrenalectomy (ADX) has been shown to cause selective degeneration of granule cells in the dentate gyrus (DG). This occurs due to the reduction of corticosterone (CORT) and behavioural deficits are associated with the loss of these neurons. Dentate lesions and cell loss associated with ADX have been shown to effect behaviour in a number of spatial tasks. In contras, it has been shown granule cell loss does not affect the specificity of place cells in CA3 and CA1. We used the ADX model to examine the role of DG granule cells plays in representing space using immediate early gene (IEG) activatio

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Yim, Tonia Tan-Ling, and University of Lethbridge Faculty of Arts and Science. "Multiple-object memory requires the hippocampus." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007, 2007. http://hdl.handle.net/10133/678.

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This thesis investigates the role of the hippocampus in object memory. Currently, the role of the hippocampus in object recognition is unclear, with some studies demonstrating a delay-dependent impairment after hippocampal damage, others showing no impairment. The present thesis used the novel object recognition task and its variants to investigate various types of object memory in hippocampal lesion rats. In the first study, impairments were observed in discriminating object order and associating objects with contexts, while no impairment was observed in novel object recognition. In the secon

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Bennison, John Charles. "Gait Analysis in Anterior Cruciate Ligament Reconstruction & Controls Across Different Levels of Visual Feedback." Ohio University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1617872112807014.

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Cless, Isabelle T. "A Dissection of Pacing in Zoo-Housed Polar Bears: How Details of the Behavior Can Suggest Motivational and Causal Factors." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1435017139.

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Chien, Chih-Hao. "POTENTIAL OPTIMAL GAIT PERFORMANCE OF MAUCH S-N-S PROSTHETIC KNEE CONFIGURATIONS AS PREDICTED BY DYNAMIC MODELING." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1417068842.

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Spanswick, Simon, and University of Lethbridge Faculty of Arts and Science. "Adrenalectomy-induced neuronal degeneration : development of a novel animal model of cognitive dysfuntion and neurogenic treatment strategies." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, 2010, 2010. http://hdl.handle.net/10133/2587.

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Long-term adrenalectomy (ADX) results in a specific loss of dentate gyrus granule cells in the hippocampus of adult rats, occurring over a period of weeks to months. This loss of granule cells results in cognitive deficits in a number of tasks that depend on intact hippocampal function. The gradual nature of ADX-induced cell death and the ensuing deficits in cognition are similar to those experienced by patient populations suffering from a variety of pathological conditions. Here we present an animal model by which we use ADX to produce a loss of granule cells within the hippocampus of rats. W

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Nemati, Farshad, and University of Lethbridge Faculty of Arts and Science. "Contribution of brain with or without visual cortex lesion to exploratory locomotion in the rat." Thesis, Arts and Science, 2008. http://hdl.handle.net/10133/665.

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Over the past five decades spatial behavior has been a subject of research interest in psychology and neuroscience, in part based on philosophical theories of mental spatial representations. In order to continue uncovering the facts regarding spatial behavior, the focus of this thesis was on the contribution of entry point and visual inputs to the organization of exploratory locomotion and spatial representation in the rat. Despite the contribution of the hippocampus to spatial abilities, the exploratory locomotion is still visually organized in rats with damage to the hippocampus. On the othe

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楊可儀 and Ho-yee Yeung. "Study on the function and regulation of stanniocalcin in mouse neuroblastoma cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31245043.

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48

Merrifield, Matthew, and University of Lethbridge Faculty of Arts and Science. "Radiation-induced deregulation of PiRNA pathway proteins : a possible molecular mechanism underlying transgenerational epigenomic instability." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Science, c2011, 2011. http://hdl.handle.net/10133/2617.

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PiRNAs and their Piwi family protein partners are part of a germline specific epigenetic regulatory mechanism essential for proper spermatogenesis, silencing of transposable elements, and maintaining germline genome integrity, yet their role in the response of the male germline to genotoxic stress is unknown. Ionizing radiation (IR) is known to cause transgenerational genome instability that is linked to carcinogenesis. Although the molecular etiology of IR-induced transgenerational genomic instability is not fully understood, it is believed to be an epigenetically mediated phenomenon. IR-indu

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Kanchwala, Mustafa Ashiq Hussain. "A Miniature Wireless Neural Recording and Stimulating System for Chronic Implantation in Freely Moving Animals." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case153079448199171.

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Faraji, Jamshid, and University of Lethbridge Faculty of Arts and Science. "Structural alterations in the hippocampus and spatial behavior by stress in male and female rats : protections, and recovery in water-based and dry-land tasks." Thesis, Lethbridge, Alta : University of Lethbridge, Faculty of Arts and Science, 2008, 2008. http://hdl.handle.net/10133/725.

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Stress-related cognitive changes are still a matter of debate. In some particular neuropathological conditions such as focal ischemia, cognitive functions have been shown to be significantly impaired. These conditions, however, may be improved by some factors such as steroid hormones. The purpose of the current thesis was to assess the structural and functional effects of corticosterone-related experiences on the hippocampus before and after endothelin-1 (ET-1)-induced stroke. We found corticosterone-related experiences enhance the hippocampal recovery, and improve its function in both wet and

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