Academic literature on the topic 'Gamma‐interferon‐inducible lysosomal Thiol Reductase'
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Journal articles on the topic "Gamma‐interferon‐inducible lysosomal Thiol Reductase"
Nguyen, Jennifer, Richard Bernert, Kevin In, Paul Kang, Noemi Sebastiao, Chengcheng Hu, and K. Taraszka Hastings. "Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma." Melanoma Research 26, no. 2 (April 2016): 125–37. http://dx.doi.org/10.1097/cmr.0000000000000230.
Full textZhou, Lidan, Weili Yan, Lin Yang, Hui Chen, Qianqian Cao, and Wenhua Ren. "Isolation of gamma-interferon-inducible lysosomal thiol reductase (GILT) from the Yangtze finless porpoise." Developmental & Comparative Immunology 41, no. 4 (December 2013): 652–56. http://dx.doi.org/10.1016/j.dci.2013.06.012.
Full textArunachalam, B., U. T. Phan, H. J. Geuze, and P. Cresswell. "Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a Gamma-interferon-inducible lysosomal thiol reductase (GILT)." Proceedings of the National Academy of Sciences 97, no. 2 (January 18, 2000): 745–50. http://dx.doi.org/10.1073/pnas.97.2.745.
Full textHastings, Karen Taraszka, and Peter Cresswell. "Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase." Antioxidants & Redox Signaling 15, no. 3 (August 2011): 657–68. http://dx.doi.org/10.1089/ars.2010.3684.
Full textIn, K., H. Menon, J. Nguyen, N. Sebastiao, P. Kang, C. Hu, R. Bernert, D. J. DiCaudo, and K. T. Hastings. "290 Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma and halo nevi." Journal of Investigative Dermatology 136, no. 5 (May 2016): S51. http://dx.doi.org/10.1016/j.jid.2016.02.320.
Full textGao, Lili, Ao Li, Yanhua Lv, Mujie Huang, Xi Liu, Hongkuan Deng, Dongwu Liu, Bosheng Zhao, Baohua Liu, and Qiuxiang Pang. "Planarian gamma-interferon-inducible lysosomal thiol reductase (GILT) is required for gram-negative bacterial clearance." Developmental & Comparative Immunology 116 (March 2021): 103914. http://dx.doi.org/10.1016/j.dci.2020.103914.
Full textCao, Fang, Haitao Wu, Tongtong Lv, Yunqing Yang, Yue Li, Shuaimei Liu, Lingling Hu, et al. "Molecular and biological characterization of gamma-interferon-inducible lysosomal thiol reductase in silver carp (Hypophthalmichthys molitrix)." Fish & Shellfish Immunology 79 (August 2018): 73–78. http://dx.doi.org/10.1016/j.fsi.2018.04.064.
Full textRen, Chunhua, Ting Chen, Xiao Jiang, Xing Luo, Yanhong Wang, and Chaoqun Hu. "The first echinoderm gamma-interferon-inducible lysosomal thiol reductase (GILT) identified from sea cucumber (Stichopus monotuberculatus)." Fish & Shellfish Immunology 42, no. 1 (January 2015): 41–49. http://dx.doi.org/10.1016/j.fsi.2014.10.024.
Full textKongton, Kittima, Kimberly McCall, and Amornrat Phongdara. "Identification of gamma-interferon-inducible lysosomal thiol reductase (GILT) homologues in the fruit fly Drosophila melanogaster." Developmental & Comparative Immunology 44, no. 2 (June 2014): 389–96. http://dx.doi.org/10.1016/j.dci.2014.01.007.
Full textSrinivasan, Priya, and Maja Maric. "Signal transducer and activator of transcription 1 negatively regulates constitutive gamma interferon-inducible lysosomal thiol reductase expression." Immunology 132, no. 2 (October 13, 2010): 209–16. http://dx.doi.org/10.1111/j.1365-2567.2010.03355.x.
Full textDissertations / Theses on the topic "Gamma‐interferon‐inducible lysosomal Thiol Reductase"
Bogunovic, Branka. "The role of Gamma interferon Inducible Lysosomal Thiol reductase (GILT) in immune and cellular functions." Connect to Electronic Thesis (ProQuest) Connect to Electronic Thesis (CONTENTdm), 2008. http://worldcat.org/oclc/436442487/viewonline.
Full textJohnson, Kenneth. "The Role of Gilt in the Cross Presentation of the Melanoma Antigen gp100." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/623465.
Full textIn this study we examine the utility of using CD8+ T cell hybridomas to measure the ability of bone marrow dendritic cells (BMDCs) to internalize cancer proteins and display them to cytotoxic T cells, a process termed cross‐presentation. We test the ability of a newly generated T cell hybridoma called BUSA14 to detect cross‐presentation of the melanoma antigen gp100. BUSA14 produces a dose‐dependent response to human and mouse gp100 peptides. However, cross‐presentation of gp100 by BMDCs using SK‐MEL‐28 human melanoma cell lysates or direct MHC class I‐restricted presentation by B16 murine melanoma cells was not detected. Both SKMEL‐28 and B16 cells express gp100 protein by immunoblot, and gp100 as a membrane bound protein may be concentrated by cell fractionation techniques. We validated our crosspresentation assay with another T cell hybridoma B3Z to detect cross‐presentation of the model antigen ovalbumin. Lastly, we determined that although BUSA14 expresses the coreceptor CD8, BUSA14 lacks CD3 expression, which likely impairs the ability of this hybridoma to respond to engagement of the T cell receptor and contributes to the inability to detect presentation of native gp100 protein. To resolve these issues, we plan to use primary gp100‐specific T cells from pmel mice expressing the same T cell receptor as the BUSA14 hybridoma to detect presentation of gp100 protein. Ultimately, we plan to evaluate the requirements for cross‐presentation of gp100, including a role for gamma‐interferon‐inducible lysosomal thiol reductase (GILT), a disulfide bond reducing enzyme.
Chan, Tzu Hsuan, and 詹子萱. "Significant induction of gamma-interferon-inducible lysosomal thiol reductase in the retinal pigment epithelial cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/hqqgu5.
Full textLin, Yi Chen, and 林沂蓁. "Effects of Gamma-Interferon-Inducible Lysosomal Thiol Reductase (GILT) on Antigen Presentation in Retinal Pigment Epithelium (RPE) Cells." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/amr6h9.
Full textBook chapters on the topic "Gamma‐interferon‐inducible lysosomal Thiol Reductase"
Meador, Lydia R., and Karen Taraszka Hastings. "Gamma-Interferon-Inducible Lysosomal Thiol Reductase (GILT)." In Encyclopedia of Signaling Molecules, 2007–21. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101662.
Full textMeador, Lydia R., and Karen Taraszka Hastings. "Gamma-Interferon-Inducible Lysosomal Thiol Reductase (GILT)." In Encyclopedia of Signaling Molecules, 1–15. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101662-1.
Full textPhan, Uyen T., Maja Maric, and Peter Cresswell. "[5] Disulfide reduction in major histocompatibility complex class II-restricted antigen processing by interferon-γ-inducible lysosomal thiol reductase." In Protein Sensors and Reactive Oxygen Species - Part B: Thiol Enzymes and Proteins, 43–48. Elsevier, 2002. http://dx.doi.org/10.1016/s0076-6879(02)48624-7.
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