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Relevant bibliographies by topics / Gastric ulceration model

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Academic literature on the topic 'Gastric ulceration model'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Gastric ulceration model"

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Eaton, K. A., M. J. Radin, and S. Krakowka. "An Animal Model of Gastric Ulcer Due to Bacterial Gastritis in Mice." Veterinary Pathology 32, no. 5 (1995): 489–97. http://dx.doi.org/10.1177/030098589503200506.

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Conventional female BalbC mice were inoculated with Gastrospirillum-like bacteria in mouse gastric homogenate or in 5.0-μm filtrate of gastric homogenate. The bacteria were originally isolated from cheetahs with gastritis. The mice were killed 6 months, 7 months, or 1 year after inoculation. All mice became infected with Gastrospirillum-like bacteria that were confined to the gastric mucosa. Control mice, given either sterile Brucella broth, 0.22-μm filtrate of infected gastric homogenate, or uninfected gastric homogenate did not become infected with bacteria. Lesions in infected mice included

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Zalecki, Michal, Adrianna Plywacz, Hanna Antushevich, and Amelia Franke-Radowiecka. "Cocaine and Amphetamine Regulated Transcript (CART) Expression Changes in the Stomach Wall Affected by Experimentally Induced Gastric Ulcerations." International Journal of Molecular Sciences 22, no. 14 (2021): 7437. http://dx.doi.org/10.3390/ijms22147437.

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Cocaine- and amphetamine-regulated transcript (CART) is a peptide suggested to play a role in gastrointestinal tract tissue reaction to pathology. Gastric ulceration is a common disorder affecting huge number of people, and additionally, it contributes to the loss of pig livestock production. Importantly, ulceration as a focal disruption affecting deeper layers of the stomach wall differs from other gastrointestinal pathologies and should be studied individually. The pig’s gastrointestinal tract, due to its many similarities to the human counterpart, provides a valuable experimental model for

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Malash, Asmaa M., Dalaal M. Abdallah, Azza M. Agha, and Sanna A. Kenawy. "Gastroprotective Efficacy of Coenzyme Q10 in Indomethacin-Induced Gastropathy: Other Potential Mechanisms." Ulcers 2012 (February 6, 2012): 1–7. http://dx.doi.org/10.1155/2012/957898.

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Though recently the mitochondrial bioenergetic coenzyme (Co)Q10 has been shown to protect against indomethacin-induced gastric ulceration, yet the full mechanistic cassettes have not been investigated. Therefore, the current investigation assessed further gastroprotective mechanisms of CoQ10 using the indomethacin-induced gastropathy model. While CoQ10 was administered at 3 dose levels to male Wistar rats, the proton pump inhibitor, pantoprazole, was given at 4 dose levels ahead of pyloric ligation and indomethacin administration. Indomethacin evoked gastric ulcerations that were associated by

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Georgieva, Antoaneta, Danail Pavlov, Maria Tzaneva, et al. "Gastroprotective effect of the flavonoid fustin isolated from Cotinus coggygria heartwood in a rat model of indomethacin-induced gastric ulceration." Acta Scientifica Naturalis 10, no. 2 (2023): 25–38. http://dx.doi.org/10.2478/asn-2023-0012.

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Abstract Gastric ulcer is a common health issue. Cotinus coggygria heartwood extracts rich in the flavonoids fustin and sulfuretin have shown protective effects in a rat model of indomethacin-induced gastric ulceration. Fustin itself has been protective in a rat model of ethanol-induced gastric ulcer. In the present study we aimed to reveal the effect of the flavonoid fustin isolated from Cotinus coggygria heartwood in a rat model of indomethacin-induced gastric ulceration. Fustin was isolated from Cotinus coggygria heartwood and purified. The experiment was performed on 30 male Wistar rats al

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THONGSOM, Montakarn, Lanchakon CHANUDOM, and Jitbanjong TANGPONG. "Co-treatment Effect of Syzygium cumini (L.) Skeels on Indomethacin Induced Gastric Ulcer on Mice Model." Walailak Journal of Science and Technology (WJST) 16, no. 3 (2019): 193–206. http://dx.doi.org/10.48048/wjst.2019.6224.

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Syzygium cumini (L.) Skeels or SCC originally from India and Southeast Asia, commonly used as a medicinal and acted as antioxidant and anti-inflammatory plant. Indomethacin, which is a part of nonsteroidal anti-inflammatory drugs (NSAIDs) family, induced gastric damage and perforation through the excess generation of reactive oxygen species (ROS). This research focus on co-treatment administered between SCC and indomethacin in the subsequent 7 days and evaluated on oxidative damage, inflammatory parameter and epidermal growth factor (EGF) receptor. SCC showed a concentration and dose dependent

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Al-Qrimli, Ayah F. "The Gastroprotective Effects of Papaya Seed Crude Extract on Aspirin Induced Gastric Ulcer in Mice." Saudi Journal of Medical and Pharmaceutical Sciences 11, no. 04 (2025): 339–44. https://doi.org/10.36348/sjmps.2025.v11i04.016.

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The seeds of carica papaya fruit have been studied for its gastroprotective action on patients with gastric ulcer due to its rich phytochemical constituents that have strong antioxidants and anti-inflammatory activity. The seeds of the newly cultivated in Iraq c.papaya plant were collected and extracted via Soxhlet apparatus using 70% aqueous ethanol. The ethanolic extract was phytochemically investigated to show the presence of flavonoids, phenolic compounds, alkaloids and saponins. Our in-vitro study model of the gastro protective action of the seed extract used aspirin for the induction of

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Jean-Baptistea, Oussou N’Guessan, Goze Nomane Bernarda, Ehilé Ehilé Hervéa, Grahouan Pizito Stéphanea, Kouakou Kouakou Léandrea, and Yapo Angoué Paula. "Preventive and Healing Effects of the Total Aqueous Extract of the Trunk Bark of Zanthoxylum gilletii (De Wild.) P. G. Waterman (Rutaceae) on Gastric Acid Reflux and Non-reflux Induced Esophagitis in Rats." European Journal of Medicinal Plants 34, no. 8 (2023): 41–57. http://dx.doi.org/10.9734/ejmp/2023/v34i81153.

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Zanthozylum gilletii is a medicinal plant well known for its richness in phytochemicals and its use in Côte d’Ivoire in the traditional treatment of burns in esophagus. However, its bioactive anti-reflux and non-reflux oesophagitis potential has not yet been scientifically proven. This work aims at evaluating the preventive and curative anti-esophagitis potential of a total aqueous extract of Z. gilletii trunk bark (TAEZg) in rats. Thirty-six rats were subjected to 24 hours fast and divided into six groups of six rats each were used for each model of esophagitis induction, in particular the pr

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Yao, Jinfu. "Tiao He Yi Wei Granule, a Traditional Chinese Medicine, against Ethanol-Induced Gastric Ulcer in Mice." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/647283.

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Tiao He Yi Wei granule (DHYW), a traditional Chinese medicine, has been used for the treatment of gastric ulcer in clinical setting. The purpose of the present study was to investigate the possible effect of DHYW and explore the underlying mechanism against ethanol-induced gastric ulcer in mice. The model of ethanol-induced gastric ulcer in mice was induced by ethanol (0.2 mL/kg). Administration of DHYW at the doses of 250, 500 mg/kg body weight prior to the ethanol ingestion could effectively protect the stomach from ulceration. The gastric lesions were significantly ameliorated in the DHYW g

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Adefisayo, Modinat A., Rufus O. Akomolafe, Olumide S. Akinsomisoye, et al. "Protective Effects of Methanol Extract of Vernonia amygdalina (del.) Leaf on Aspirin-Induced Gastric Ulceration and Oxidative Mucosal Damage in a Rat Model of Gastric Injury." Dose-Response 16, no. 3 (2018): 155932581878508. http://dx.doi.org/10.1177/1559325818785087.

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This study investigated the quantitative polyphenolic constituents and gastroprotective effects of methanol extract of Vernonia amygdalina leaf (MEVA) against aspirin-induced gastric ulcer in rats. Ulceration was induced by 3 days’ oral administration of aspirin (150 mg/kg body weight). Wistar rats were pretreated with cimetidine (reference drug) at a dose of 100 mg/kg body weight and MEVA at 200, 300, and 400 mg/kg body weight once daily for 28 days prior to ulcer induction. At the end of the experiment, gastric secretions, antioxidant status, and histopathological alteration were evaluated.

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Bhatti, Maira. "Prophylactic Gastric Histopathological Evaluation of Fluvoxamine and Mirtazapine in Aspirin Induced Rat Model." Proceedings of Shaikh Zayed Medical Complex Lahore 34, no. 1 (2020): 6–10. http://dx.doi.org/10.47489/p000s342z7351-5mc.

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Introduction: Depression is a mood disorder characterized by emotional dysregulation that causes distress in patients. It has strong association with peptic ulcer due to the underlying factor, stress, involved in its pathogenesis. The increased usage of NSAIDS and associated peptic ulcer disease (PUD) in depressive patients has raised concerns. Standard treatment is with PPIs like omeprazole Antiulcer effect of antidepressants fluvoxamine and mirtazapine was investigated in our previous research work by comparing the gastric glutathione and PGE2 levels in aspirin induced ulcer in rats. Aims &a

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Books on the topic "Gastric ulceration model"

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Szabo, Sandor, Gary B. Glavin, and Yvette Taché. Neuroendocrinology of Gastrointestinal Ulceration. Springer London, Limited, 2012.

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Book chapters on the topic "Gastric ulceration model"

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Beydoun, May A., and Ziad W. El-Hajj. "Helicobacter pylori and Cognitive Dysfunction." In Infectious Diseases in Neurocognitive and Neuropsychiatric Medicine. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/oso/9780192870414.003.0012.

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Abstract Helicobacter pylori (Hp) is a curved Gram-negative bacterium found in almost half of human gastric mucosa and is one of the most common infectious agents worldwide. Often acquired during childhood, its mode of transmission is still under debate, but its seroprevalence increases with age, under poor socioeconomic conditions, crowding, poor hygiene, and among minority groups. Since first described in 1984 as a bacterium in the stomachs of patients with gastritis and peptic ulceration, Hp infection was further found to account for other digestive conditions, including duodenal ulcers, ga

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