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Journal articles on the topic 'Gastroduodenal ulcers'

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1

Pimanov, S. I., E. I. Mikhailova, and E. V. Voropaev. "FECAL CALPROTECTIN IN SCREENING DIAGNOSTICS OF GASTRODUODENAL ULCERS." Health and Ecology Issues, no. 2 (June 28, 2006): 58–63. http://dx.doi.org/10.51523/2708-6011.2006-3-2-11.

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Gastroduodenal ulcers is one of the most common diseases of digestive organs. The absence of stable tendency towards the lower morbidity with this pathology, frequent recurrent course, complication severity and high rate of disability of patients make researchers to clarify etiological and pathogenetic aspects of ulcer, to develop and improve the known methods of diagnostics and treatment of patients. We have investigated the efficiency of fecal calprotectin use in the screening diagnostics of gastroduodenal ulcers in 36 patients with gastroduodenal ulcers, 43 patients with gastric cancer, and
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2

Vainshtein, S. G., Z. I. Shust, M. N. Zhukovsky, and Ya N. Fedoriv. "Local treatment of gastroduodenal ulcers." Kazan medical journal 67, no. 6 (1986): 403–4. http://dx.doi.org/10.17816/kazmj70743.

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In spite of the established ideas about peptic ulcer as a general disease of the whole organism, there is a continuous flow of publications in which local treatment of ulcers of the mucous membrane of the stomach and duodenum is recommended. With the development of fiber optics, it became possible to target the ulcers, activating reparation processes in them. Adhesives and film-forming compositions MK-6, Lifusol, Gastrovol etc. were used to cover the ulcers.
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3

Ashcroft, Darren M., Stephen R. Chapman, Wendy K. Clark, and David S. Millson. "Upper Gastroduodenal Ulceration in Arthritis Patients Treated with Celecoxib." Annals of Pharmacotherapy 35, no. 7-8 (2001): 829–34. http://dx.doi.org/10.1345/aph.10382.

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OBJECTIVE: To evaluate the comparative incidence of endoscopic gastroduodenal ulcers in patients with rheumatoid arthritis or osteoarthritis treated with celecoxib. DESIGN: Quantitative systematic review of randomized controlled trials. SUBJECTS: Patients (n = 4632) with rheumatoid arthritis or osteoarthritis reported in five trials. MAIN OUTCOME MEASURES: Rate ratios, rate differences, and the number needed to harm were calculated for the incidence of endoscopically documented gastroduodenal ulcers. RESULTS: Pooled rate ratios (RRs) relative to placebo for endoscopic ulcers at 12 weeks were 1
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4

Osmanov, Z. H., M. G. Rybakova, Yu A. Tikhonova, D. Ju Semenov, A. Yu Korolkov, and A. A. Mylnikova. "Morphological features of complicated gastroduodenal ulcers." Scientific Notes of the Pavlov University 29, no. 1 (2022): 54–62. http://dx.doi.org/10.24884/1607-4181-2022-29-1-54-62.

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The objective of the study was to evaluate structural changes in the margin of gastroduodenal ulcers complicated by perforation, bleeding or penetration in terms of the features of ulcer healing.Methods and materials. Histological and IHC studies were performed on 25 patients of the main group with perforated gastroduodenal ulcers and 23 patients of the control group with chronic recurrent ulcers complicated by bleeding and penetration. Histological sections were stained with hematoxylin and eosin, and Van Gieson's picrofuchsin. Immunohistochemical reactions were performed with antibodies to K
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5

Fomina, L. A. "Calcium imbalance in comorbid gastroduodenal ulcers." Medical alphabet, no. 35 (December 18, 2021): 30–33. http://dx.doi.org/10.33667/2078-5631-2021-35-30-33.

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Purpose of the study. To study the level of blood calcium, reflecting the functional state of the calcium-regulating system (CRS), in the comorbid course of gastroduodenal ulcers (GDU) with chronic erosive gastritis / chronic erosive duodenitis (CEG/CED), arterial hypertension (AH), their symptomatic nature when taking non-steroidal drugs (NSAIDs) and find out its effect on the activity of the ulcerous process, the state of regional microcirculation and the secretory function of the stomach.Materials and methods. 132 patients with GDU were examined. All patients were divided into groups: the f
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6

Kuznetsov, V. A., B. L. Elyashevich, A. F. Ageev, and I. V. Fedorov. "New methodological approaches to surgical treatment of gastroduodenal ulcers." Kazan medical journal 70, no. 6 (1989): 412–14. http://dx.doi.org/10.17816/kazmj101573.

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We analyzed the experience of surgical treatment of 2000 patients with peptic ulcer since 1965. The main result of the study can be reduced to two main statements:
 1) the problem of surgical treatment of gastroduodenal ulcers cannot be solved by a single unified surgical technique;
 2) further progress in surgical treatment of gastroduodenal ulcers should be expected in the way of objectification of indications for early surgery, intensification of preoperative preparation, improvement of methodical approaches to surgical interventions and their technical solution.
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7

Magomedov, M. М., M. D. Omarov, and M. A. Magomedov. "Analysis of risk factors for postoperative complications in assessing the results of surgical treatment of patients with perforated ulcer." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 13, no. 4 (2023): 52–56. http://dx.doi.org/10.20340/vmi-rvz.2023.4.clin.4.

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Emergency operations for perforated gastroduodenal ulcers are associated with a high incidence of postoperative complications. A number of studies have examined the impact of perioperative risk factors and comorbidities on postoperative morbidity after abdominal surgery, but only a few have looked at their role in perforated peptic ulcer disease.Aim. To determine possible associations between postoperative complications, comorbidity and perioperative risk factors for perforated gastroduodenal ulcer.Materials and methods. This study includes the anamnesis of 142 patients who underwent surgery f
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8

Zherlov, G. K., A. P. Koshel, V. M. Vorobiyov та Yu D. Yermolayev. "Язвенная болезнь желудка и двенадцатиперстной кишки: выбор тактики при кровотечении". Bulletin of Siberian Medicine 5, № 1 (2006): 76–80. http://dx.doi.org/10.20538/1682-0363-2006-1-76-80.

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Ulcerative gastroduodenal bleedings remain the actual problem of emergency surgery because of quite frequency and high mortality. The analysis of treatment results in 782 patients was conducted. There were 239 patients with gastric ulcers, 488 patients with duodenal ulcers, 37 patients with combined ulcers and 18 patients with bleeding peptic ulcers of gastroenteranastomosis. The choice of surgical policy was based on emergency fibrogastroscopy findings. According to these findings the locality and severity of bleeding were defined using J. Forrest scale. The treatment began in intensive care
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9

Al-Ganmi, Ali Hussein Alek, Haider Mohammed Majeed, and Ahmed Fleih Hassan. "Examining of Predictive Factors for Developing Gastroduodenal Ulcer among Patients Attending Gastrointestinal Teaching Hospitals in Baghdad." Journal of Nature and Science of Medicine 8, no. 2 (2025): 146–50. https://doi.org/10.4103/jnsm.jnsm_107_24.

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Background and Objectives: Duodenal and gastric ulcers remain the two most common perforations of the gastrointestinal tract and might be reduced by the early detection of predictive factors, which has limitedly researched. This study conducted to examine the predictive factors for developing of gastroduodenal ulcer among patients attending Gastrointestinal Teaching Hospitals in Baghdad, Iraq. Materials and Methods: A cross-sectional survey with a total of 100 patients with gastric and duodenal ulcers was recruited using a nonprobability (purposive) sampling technique from September 10, 2022 t
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10

Lee, Wil Sern, Hui Jun Ong, Zi Wei Chua, and Kok Beng Loh. "THE EFFECTIVENESS OF EMPIRIC TRANSARTERIAL GLUE EMBOLIZATION (TAGE) OF GASTRODUODENAL ARTERY (GDA) FOR BLEEDING DUODENAL ULCER - A RETROSPECTIVE STUDY." Interventionalist Journal 4, no. 2 (2024): 1–10. http://dx.doi.org/10.32896/tij.v4n2.1-10.

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ABSTRACT: Purpose To conduct a clinical audit on clinical outcome of empiric transarterial glue embolization (TAGE) of gastroduodenal artery (GDA) for bleeding duodenal ulcers to evaluate treatment efficacy. Materials and Methods All patients treated for bleeding duodenal ulcers between June 2019 and June 2023, in a single tertiary center (Penang General Hospital) were identified based on intervention radiological reports. Patients with bleeding duodenal ulcers underwent empiric transarterial glue embolization (TAGE) of gastroduodenal artery (GDA) following endoscopic hemostasis were included.
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11

Soshin, A. N. "Treatment of chronic gastroduodenal ulcers associated with Helicobacter Pylori-infection." Kazan medical journal 77, no. 4 (1996): 303. http://dx.doi.org/10.17816/kazmj104546.

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Treatment of chronic gastroduodenal ulcers remains one of the most difficult and unsolved problems. The main difficulty that they try to overcome is their recurrent course. Nowadays the main directions of medical therapy of peptic ulcer disease are the decrease of intragastric acidity and sanation of gastroduodenal mucosa from Helicobacter Pylori. Treatment aimed at the destruction of Helicobacter Pylori allows to reduce the relapse rate to almost zero, provided it is successfully suppressed.
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12

Melnyk, I. V., and S. B. Soliev. "The original scale prediction of recurrence risk of gastroduodenal ulcer bleeding." Experimental and Clinical Gastroenterology, no. 2 (April 7, 2021): 72–78. http://dx.doi.org/10.31146/1682-8658-ecg-186-2-72-78.

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Research goal - to examine the effectiveness of active-individualized tactics in treatment of chronic gastric and duodenal ulcers. Material and methods. Analysis of treatment of 251 patients with chronic gastric and duodenal ulcer bleeding was conducted. Duodenal ulcer bleeding was present in 202 cases (80,5%), gastric ulcers were the reason of bleeding in 49 cases (19,5%). Treatment conducted according to principles of active-individualized tactics. Results. The provided characteristics and the acquired results were presented according to the fundamental components of active-individualized ta
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13

Pokydko, M. I., T. V. Formanchuk, O. V. Goncharenko, A. M. Formanchuk, and V. A. Katsal. "The complex treatment of patients with perforated gastroduodenal ulcers." Reports of Vinnytsia National Medical University 22, no. 3 (2018): 479–84. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(3)-17.

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To improve the immediate results of surgical treatment of patients with perforated gastroduodenal ulcers using minimally invasive correction and an integrated treatment. The results of 253 patients with perforated gastroduodenal ulcers who were treated from 2013 to 2018 were analyzed. Chronic ulcers were found in 82 (32%) cases among all gastric ulcers, acute ones constituted 42 (16%) cases. Chronic duodenal ulcers reached 94 (37%), acute ones constituted 35 (14%). The diagnostic laparoscopy was performed in 13 (5%) patients, in 8 (3%) patients the perforated hole was sutured laparoscopically
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14

Samartsev, Vladimir A., Aleksandr A. Parshakov, Marina P. Kuznetsova, and Aleksandr A. Muhanov. "Perforated gastroduodenal ulcers: perioperative prognosis and prevention of complications." Perm Medical Journal 41, no. 5 (2024): 27–34. http://dx.doi.org/10.17816/pmj41527-34.

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Objective. To improve the effectiveness of treatment for patients with perforated gastroduodenal ulcers (PGDU) by developing criteria for predicting postoperative complications and mortality. Materials and methods. The treatment outcomes of 127 patients with PGDU were analyzed. Prognostic scales ASA, SOFA, Peptic Ulcer Perforation Score (PULP), and the Mannheim Peritonitis Index (MPI) were used for the assessment in all the patients. Specialized classifications (DEP and ulcer defect classes) developed at Sklifosovsky Research Institute For Emergency Medicine were employed to determine the surg
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15

ERASMUS, J. F. P. "GASTRODUODENAL ULCERS AND NEOPLASMS." Acta Medica Scandinavica 152, S306 (2009): 26–38. http://dx.doi.org/10.1111/j.0954-6820.1955.tb16279.x.

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16

Verbitsky, Vladimir G., Anton O. Parfenov, Andrey E. Demko, Ivan P. Yastrebov, Alexey V. Kosachev, and Egor V. Yurkevich. "Surgical treatment of patients with ulcerative gastroduodenal bleeding: clinical cases." HERALD of North-Western State Medical University named after I.I. Mechnikov 16, no. 4 (2024): 134–39. https://doi.org/10.17816/mechnikov630237.

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The article presents two clinical cases of treatment of treating patients with ulcerative gastroduodenal bleeding from large chronic ulcers. In one case, the source of bleeding was a giant callous chronic gastric ulcer. The patient urgently underwent subtotal gastric resection with an inter-intestinal anastomosis according to the Roux procedure (18 hours after admission to the hospital), taking into account the high risk of recurrence of bleeding. In the second case, a patient with bleeding from a large chronic duodenal ulcer was operated on urgently (24 hours after admission to the hospital)
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17

Pokidko, M. I., V. V. Balabuyeva, O. V. Goncharenko, and M. G. Bogachuk. "ANALYSIS OF MODERN COMPLEX TREATMENT OF PATIENTS WITH PERFORATED GASTRODUODENAL ULCER." Kharkiv Surgical School, no. 2-3 (June 28, 2024): 107–12. http://dx.doi.org/10.37699/2308-7005.2-3.2024.23.

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Abstract. The goal is to improve the results of complex treatment of patients with a perforated gastroduodenal ulcer by analyzing the results of treatment using traditional surgical techniques and using minimally invasive, including endoscopic vacuum-associated (E-VAK) interventions. The results of treatment of 287 patients with gastric and duodenal ulcers complicated by perforation, who were treated in the surgical department of the city clinical emergency medical hospital during 2019-2023, were studied. Among gastric ulcers, chronic ulcers were found in 78 (27.2 %) cases, acute – in 34 (11.8
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18

Kachanovsky, Yaroslav, and Ihor Dzubanovsky. "MORPHOLOGICAL CHARACTERISTICS OF CHANGES IN THE PERIULCEROUS ZONE OF BLEEDING GASTRODUODENAL ULCERS DEPENDING ON THE DEGREE OF BLEEDING ACTIVITY ACCORDING TO FORREST." Clinical anatomy and operative surgery 23, no. 1 (2024): 75–79. http://dx.doi.org/10.24061/1727-0847.23.1.2024.11.

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Despite the signifi cant decrease in morbidity and mortality rates due to peptic ulcer disease of the stomach and duodenum over the past few decades, complications still occur in 10-20 % of patients. Of these, bleeding is the most common complication of peptic ulcers, with an average 30-day mortality of up to 8.6 %. The aim of the study was to evaluate histological changes in the periulcerous zone of active bleeding gastroduodenal ulcers in patients with diff erent degrees of activity of gastroduodenal bleeding according to Forrest. 378 patients with chronic bleeding ulcers of the stomach and du
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19

Xu, Fang, Cai-ling Mai, and Qian Zhu. "Association of TLR-9 polymorphisms with the development of gastroduodenal ulcer: A hospital-based study in a Chinese cohort." European Journal of Inflammation 16 (January 1, 2018): 1721727X1875726. http://dx.doi.org/10.1177/1721727x18757262.

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Helicobacter pylori infections have been one of the major factors associated with gastroduodenal ulcer. Toll-like receptors (TLRs) of human recognize mycobacterium-induced immune response and protect subjects from disease pathogenesis. Variants in TLR genes are believed to influence immune responses to H. pylori and clinical severity. TLR-9 polymorphisms have been associated with susceptibility to gastroduodenal ulcer in different populations. In this study, we investigate the role of common TLR-9 variants in susceptibility/resistance to the development of gastroduodenal ulcer in a Chinese coh
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20

Sun, Mei, Zhe Zhang, Jingjing Zhang, et al. "Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization." PLOS ONE 19, no. 4 (2024): e0300835. http://dx.doi.org/10.1371/journal.pone.0300835.

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Background Previous observational studies have demonstrated a connection between the risk of Type 2 diabetes mellitus (T2DM) and gastrointestinal problems brought on by Helicobacter pylori (H. pylori) infection. However, little is understood about how these factors impact on T2DM. Method This study used data from the GWAS database on H. pylori antibodies, gastroduodenal ulcers, chronic gastritis, gastric cancer, T2DM and information on potential mediators: obesity, glycosylated hemoglobin (HbA1c) and blood glucose levels. Using univariate Mendelian randomization (MR) and multivariate MR (MVMR)
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21

Dudchenko, Maksym, Nataliia Tretyak, and Maksym Dudchenko. "Gastric Ulcer and Duodenal Ulcer in the Family Doctor Practice." Family Medicine, no. 5 (November 30, 2016): 106–10. https://doi.org/10.30841/2307-5112.5.2016.248802.

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Peptic ulser disease is a chronic polyetiogical recurrent disease with impaired of neuro-endocrine and humoral mechanisms controlling secretory – trophic processes in the gastroduodenal area with ulcers development. It belongs to widespread diseases in the world with a tendency to increase. Peptic ulcers have different localization and dinical course. The treatment of the patient with ulcers should be staged, conservative comprehensive and individual in pharmacolotherapy prescriptions. The best variant in the treatment process is Hp and other submucous infection eradication with using in
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22

Barannikov, S. V., E. F. Cherednikov, G. V. Polubkova, et al. "First experience of using alginate polymer polysaccharide hemostatic hydrogel in complex endoscopic treatment of unstable gastroduodenal ulcer bleeding: Clinical cases." Kuban Scientific Medical Bulletin 31, no. 3 (2024): 73–92. http://dx.doi.org/10.25207/1608-6228-2024-31-3-73-92.

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Background. Gastroduodenal ulcer bleeding continues to be a serious problem in modern emergency surgery. Early intensive therapy combined with endoscopic hemostasis remains crucial for successful treatment of patients with ulcerative hemorrhages. The problem of recurrent bleeding, which is recorded in 12–33% of cases, even when using combined methods of endoscopic hemostasis, is still the most difficult challenge in the treatment of patients with ulcerative bleeding. The search for new approaches in the endoscopic treatment of bleeding gastroduodenal ulcers is considered to be highly relevant.
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23

Dudchenko, Maksym, Nataliia Tretyak, and Maksym Dudchenko. "Gastric Ulcer and Duodenal Ulcer in the Family Doctor Practice." Family Medicine, no. 5 (December 30, 2016): 106–10. http://dx.doi.org/10.30841/2307-5112.5.2016.248802.

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Peptic ulcer disease is a chronic polyetiogical recurrent disease with impaired of neuro-endocrine and humoral mechanisms controlling secretory – trophic processes in the gastroduodenal area with ulcers development.
 It belongs to widespread diseases in the world with a tendency to increase peptic ulcers have different localization and clinical course.
 The treatment of the patient with ulcers should be staged, conservative comprehensive and individual in pharmacolotherapy prescriptions. The best variant in the treatment process is Hp and other submucous infection eradication with us
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24

SAKHABETDINOVA, KAMILIA N., BULAT A. SAKHABETDINOV, and NAIL B. AMIROV. "COMORBIDITY AS A FACTOR OF GASTRODUODENAL ULCER DEVELOPMENT IN ELDERLY AND SENILE PATIENTS." Bulletin of Contemporary Clinical Medicine 17, no. 6 (2024): 84–96. https://doi.org/10.20969/vskm.2024.17(6).84-96.

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Introduction. Peptic ulcer disease is a chronic recurrent multifactorial disease that takes its course with alternating exacerbations and remissions and is manifested by ulcerative defects in the mucous membrane of the stomach and duodenum, which is based on an imbalance of aggressive and protective factors with a predominance of ВЕСТНИК СОВРЕМЕННОЙ КЛИНИЧЕСКОЙ МЕДИЦИНЫ 2024 Том 17, вып. 6 85ОБЗОРЫ the former ones. Of particular interest is the comparative characteristics of gastric and duodenal ulcers in the patients of senile and elderly age groups due to their pathogenetic features and sing
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25

Seljanina, A. A., A. I. Dolgushina, A. A. Fokin, A. S. Kuznecova, and V. V. Genkel'. "Upper gastrointestinal lesions in patients with lower extremity peripheral artery disease: data from a retrospective analysis." Cardiovascular Therapy and Prevention 21, no. 2 (2021): 2990. http://dx.doi.org/10.15829/1728-8800-2022-2990.

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Aim. To assess the prevalence and structure of upper gastrointestinal (GI) lesions, as well as the factors associated with their development, in patients with lower extremity peripheral artery disease (PAD).Material and methods. This retrospective analysis of medical records with lower extremity PAD includes data from 258 patients. All patients underwent multislice computed tomography angiography of abdominal aortic visceral branches and lower limb arteries, as well as esophagogastroduodenoscopy.Results. Endoscopic evidence of upper GI lesions was detected in 164 (63,6%) patients. In particula
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26

Santos-Rancaño, Rocio, Esteban Martín Antona, and José Vicente Méndez Montero. "A Challenging Case of a Large Gastroduodenal Artery Pseudoaneurysm after Surgery of a Peptic Ulcer." Case Reports in Surgery 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/370937.

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We report a 48-year-old man in whom a chronic postbulbar duodenal ulcer destroyed much of the back wall of the duodenum and gastroduodenal artery causing pseudoaneurysm. The lesion was found and evaluated by contrast-enhanced computed tomography (that revealed a large pseudoaneurysm of 83 mm×75 mm in diameter) and by angiography and then treated with transcatheter embolization leading to a complete resolution of the lesion. The case is rare and important for several reasons. First, we demonstrate that pseudoaneurysm of the gastroduodenal artery caused by a duodenal ulcer can occur and present
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27

Loffroy, Romaric, Boris Guiu, Jean-Pierre Cercueil, et al. "Refractory Bleeding From Gastroduodenal Ulcers." Journal of Clinical Gastroenterology 42, no. 4 (2008): 361–67. http://dx.doi.org/10.1097/mcg.0b013e3180319177.

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28

Tulassay, Z., J. Papp, and G. Lengyel. "Seasonal periodicity in gastroduodenal ulcers." Gastrointestinal Endoscopy 34, no. 3 (1988): 287–88. http://dx.doi.org/10.1016/s0016-5107(88)71343-7.

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29

Laurence, B. H., and P. B. Cotton. "Bleeding gastroduodenal ulcers: Nonoperative treatment." World Journal of Surgery 11, no. 3 (1987): 295–303. http://dx.doi.org/10.1007/bf01658106.

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30

van Lanschot, J. J. B., M. van Leerdam, O. M. van Delden, and P. Fockens. "Management of Bleeding Gastroduodenal Ulcers." Digestive Surgery 19, no. 2 (2002): 99–104. http://dx.doi.org/10.1159/000052019.

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31

Samsonov, V. T., A. S. Ermolov, P. A. Yartsev, A. A. Gulyaev, V. D. Levitsky, and I. I. Kirsanov. "Laparoscopy for perforated gastroduodenal ulcers." Khirurgiya. Zhurnal im. N.I. Pirogova, no. 10 (2018): 23. http://dx.doi.org/10.17116/hirurgia201810123.

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32

Miyake, Kazumasa, Masafumi Kusunoki, Tomotaka Shindo, et al. "Current Status of Gastroduodenal Ulcers." Nihon Ika Daigaku Igakkai Zasshi 6, no. 1 (2010): 7–12. http://dx.doi.org/10.1272/manms.6.7.

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33

Zherlov, G. K. "Modern trends in diagnostics and treatment of gastroduodenal ulcers." Bulletin of Siberian Medicine 2, no. 4 (2003): 5–14. http://dx.doi.org/10.20538/1682-0363-2003-4-5-14.

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In the lecture the modern views on diagnistics and tactic choice in the treatment of complicated and uncomplicated gastroduodenal ulcers have been presented and long-term results of organ-saving and organ-modeling surgery experience during complicated stomach and duodenal ulcers have been analyzed. Achievements in life quality saving of operated patients have been cited. Novel classifications of gastroduodenal anastomosis functional activity and anastomositis degrees have been proposed.
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34

Dubrovshchik, O. I., G. G. Marmysh, I. S. Dovnar, and M. I. Mileshko. "MODERN APPROACHES TO THE TREATMENT OF GASTRODUODENAL BLEEDING REQUIRING EMERGENCY SURGERY IN A SPECIALIZED CITY CENTER." Journal of the Grodno State Medical University 20, no. 2 (2022): 209–14. http://dx.doi.org/10.25298/2221-8785-2022-20-2-209-214.

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Background. Gastroduodenal bleeding (GDB) is one of the most urgent problems of emergency abdominal surgery. The frequency of detection of bleeding of non-ulcer origin, which in the past was practically not diagnosed, has increased recently due to the widespread introduction of high-tech diagnostic techniques into clinical surgical practice. Diagnostic and therapeutic algorithms for GDB of ulcerative and non-ulcerative etiology are quite clearly defined, but the problem remains relevant due to the fact that the number of patients with acute GDB does not tend to decrease. The tactics of treatin
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35

Shaprynskyi, V. O., M. V. Hmoshynskyi, and V. R. Taheiev. "INFLUENCE OF TYPE 2 DIABETES ON THE EFFICIENCY OF ENDOSCOPIC HEMOSTASIS FOR BLEEDING FROM PEPTIC GASTRODUODENAL ULCER." Kharkiv Surgical School, no. 2-3 (June 28, 2024): 36–39. http://dx.doi.org/10.37699/2308-7005.2-3.2024.07.

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Abstract. One of the most progressive methods of treatment of gastroduodenal bleeding in peptic ulcers of the stomach and duodenum is endoscopic hemostasis (EH), which is relatively safe and highly effective. Endoscopic hemostasis in gastroduodenal ulcer bleeding is achieved in more than 90% of cases. This procedure is recommended for bleeding caused by peptic ulcers of the stomach and duodenum, as a first-line method with relatively high efficiency and a small number of complications, but it is inferior to surgical methods in terms of the number of recurrences of bleeding. The aim: analysis o
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36

Lobankov, V. M., M. N. Kambalov, and S. V. Ivanov. "PERFORATED PEPTIC ULCERS: TO RAISE THE RPOBLEM." Health and Ecology Issues, no. 2 (June 28, 2007): 146–52. http://dx.doi.org/10.51523/2708-6011.2007-4-2-25.

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In order to identify the possibility of time regularity in the appearance of such ulcer complication as perforation, a study of 2200 cases of perforating ulcer incidence within the period of 1986-2005 among Gomel population has been performed. The study results have not confirmed the widespread theory of prevailing frequency of gastroduodenal ulcer perforations in spring and autumn. Dominant friqenst of perforated peptic ulcers (PPU) can be marked in any season of the year. The stated decrease in incidens of PPU - is taking place in winter season.
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37

Wong, Grace L. H., Louis H. S. Lau, Jessica Y. L. Ching, et al. "Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial." Gut 69, no. 4 (2019): 652–57. http://dx.doi.org/10.1136/gutjnl-2019-318715.

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ObjectivePatients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have a considerable risk of recurrent ulcer complications. We hypothesised that a proton pump inhibitor (lansoprazole) is superior to a histamine 2 receptor antagonist (famotidine) for the prevention of recurrent ulcer bleeding in such patients.DesignIn this industry-independent, double-blind, randomised trial, we recruited patients with a history of idiopathic bleeding ulcers. After ulcer healing, we randomly assigned (1:1) patients to receive oral lansoprazole 30 mg or famotidine 40 mg daily for 24 mo
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38

Spivakovskiy, Yu M., A. Yu Spivakovsky, Yu V. Chernenkov, O. V. Volkova, I. V. Goremykina, and A. K. Dushanova. "The case of atypical course of gastric ulcer in pediatric practice." Experimental and Clinical Gastroenterology, no. 11 (November 20, 2019): 93–99. http://dx.doi.org/10.31146/1682-8658-ecg-171-11-93-99.

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In the article, the authors present brief information about gastric ulcer and duodenal ulcer, its epidemiology, diagnostic capabilities, approaches to the treatment and prevention of complications. In addition, there are data on the diagnosis and verification of symptomatic gastroduodenal ulcers. Using the example of a clinical case of a complicated symptomatic ulcer in a child, the authors describe the difficulties encountered at the stages of diagnosis, treatment, and follow-up at high risk of complications.
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39

Sheptulin, A. A. I., S. S. Kardasheva, and A. Beer. "Idiopathic gastro-duodenal ulcers." Clinical Medicine (Russian Journal) 96, no. 8 (2018): 702–6. http://dx.doi.org/10.18821/0023-2149-2018-96-8-702-706.

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Idiopathic gastroduodenal ulcers (IGD) are stomach and duodenal ulcers not associated with Helicobacter pylori infection or with the administration of non-steroidal anti-inflammatory drugs. Their relative frequency ranges from 1.6 to 35%, and is likely to be overestimated due to frequent false negative test results. The etiology and pathogenesis of IGDH remain poorly understood. Factors contributing to their development can serve as old age, hereditary predisposition, disorders of gastric mucus, mesenteric ischemia. Compared to the positive peptic ulcer disease, PYLORI is characterized by less
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40

Shepetko, E. N., and P. D. Fomin. "CLASSIFICATION OF OPERATIONS FOR COMPLICATED GASTRODUODENAL ULCERS." Kharkiv Surgical School, no. 3-4 (December 20, 2019): 101–4. http://dx.doi.org/10.37699/2308-7005.3-4.2019.22.

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Abstract. A unified classification of operations for complicated gastroduodenal ulcers has been proposed to understand their place in the structure of surgical interventions, technological features and methods for their implementation, as well as functional efficacy and prevention of recurrent ulceration. This is a classification of operations in the pyloroduodenal zone with complicated duodenal ulcers, classification of vagotomy, classification of gastroenterostomy and classification of gastric resection. The proposed of operations classification for complicated gastroduodenal ulcers will hel
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41

Klyuev, I. I., V. M. Surin, I. N. Liksin, and V. S. Belikov. "Vagotomy in surgery of gastroduodenal ulcers." Kazan medical journal 66, no. 2 (1985): 160. http://dx.doi.org/10.17816/kazmj61219.

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42

Trofimov, Mykola, Valerii Kryshen, Yevgeniya Dytyatkovska, et al. "INDICATORS OF THE CELL-MEDIATED IMMUNITY IN SURGICAL PATIENTS WITH GASTRODUODENAL ULCERS COMPLICATED BY BLEEDING." Wiadomości Lekarskie 75, no. 1 (2022): 107–11. http://dx.doi.org/10.36740/wlek202201120.

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The aim: To determine the peculiarities of indicators dynamic of cellular level of immunity in patients with gastroduodenal ulcer complicated by bleeding and microbial contamination the periulcerous area. Materials and methods: 80 patients with gastroduodenal ulcers complicated by bleeding were studied. Among patients in the main group, 18 (22.5%) cases were patients with bleeding gastric ulcer, 56 (70%) patients with bleeding ulcer of duodenum. The study of cellular immunity are B - CD19, Natural killers(NK) - CD16, T-helpers - CD4, T-regulatory - CD8. Results: An active bleeding according to
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43

Valentini, M., R. Cannizzaro, M. Poletti, et al. "Nonsteroidal antiinflammatory drugs for cancer pain: comparison between misoprostol and ranitidine in prevention of upper gastrointestinal damage." Journal of Clinical Oncology 13, no. 10 (1995): 2637–42. http://dx.doi.org/10.1200/jco.1995.13.10.2637.

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PURPOSE The prophylactic strategy of nonsteroidal antiinflammatory drug (NSAID)-induced upper gastrointestinal (UGI) damage has largely been studied in arthritic patients, but not in cancer patients. The efficacy of misoprostol and ranitidine in the prevention of gastroduodenal damage in patients taking diclofenac for their cancer pain has been compared in this study. PATIENTS AND METHODS Patients who needed high-dose (200 to 300 mg/d) diclofenac for cancer pain and without mucosal lesions at baseline gastroduodenal endoscopy were randomized to receive misoprostol (200 micrograms twice daily;
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44

Fedorchenko, Yu L. "Chronic gastroduodenal ulcers in patients with diabetes mellitus." Problems of Endocrinology 49, no. 1 (2003): 5–10. http://dx.doi.org/10.14341/probl11320.

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The clinical picture, course, and treatment of gastroduodenal ul­cers (GDU) in diabetics were studied. A total of 395 diabetics were examined; GDU were detected in 36. The incidence of gas­tric and duodenal ulcers was similar in patients with insulin-de­pendent diabetes mellitus, while in patients with non-insulin-de- pendent diabetes gastric ulcers predominated. The clinical pic­ture of the disease, gastric acid production, Helicobacter pylori infection, and blood gastrin levels were studied in all patients with ulcers. The efficiency of GDU treatment with quamatel, raniti­dine, and antacids
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45

Fedorchenko, Yu L. "Chronic gastroduodenal ulcers in patients with diabetes mellitus." Problems of Endocrinology 49, no. 1 (2003): 5–10. http://dx.doi.org/10.14341/probl11321.

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The clinical picture, course, and treatment of gastroduodenal ul­cers (GDU) in diabetics were studied. A total of 395 diabetics were examined; GDU were detected in 36. The incidence of gas­tric and duodenal ulcers was similar in patients with insulin-de­pendent diabetes mellitus, while in patients with non-insulin-de- pendent diabetes gastric ulcers predominated. The clinical pic­ture of the disease, gastric acid production, Helicobacter pylori infection, and blood gastrin levels were studied in all patients with ulcers. The efficiency of GDU treatment with quamatel, raniti­dine, and antacids
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46

Klyuev, I. I., V. M. Surin, I. N. Piksin, and V. S. Belikov. "Vagotomy in surgery of gastroduodenal ulcers." Kazan medical journal 66, no. 2 (1985): 113–15. http://dx.doi.org/10.17816/kazmj60903.

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47

Stringer, MD, VT Veysi, JWL Puntis, G. Batcup, and MF Dixon. "Gastroduodenal ulcers in the Helicobacter pyloriera." Acta Paediatrica 89, no. 10 (2007): 1181–85. http://dx.doi.org/10.1111/j.1651-2227.2000.tb00732.x.

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48

Scheiman, James M. "Commentary: cardioprotective aspirin and gastroduodenal ulcers." Alimentary Pharmacology & Therapeutics 51, no. 1 (2019): 203. http://dx.doi.org/10.1111/apt.15532.

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49

Herrington, J. Lynwood, and Jesse Davidson. "Bleeding gastroduodenal ulcers: Choice of operations." World Journal of Surgery 11, no. 3 (1987): 304–14. http://dx.doi.org/10.1007/bf01658107.

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50

Schubert, M. L. "Treatment of NSAID-induced gastroduodenal ulcers." Gastroenterology 99, no. 5 (1990): 1533–34. http://dx.doi.org/10.1016/0016-5085(90)91197-e.

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