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1

Holak, P., and Z. Lekston. "Shape memory compression anastomosis clips in gastrointestinal surgery in dogs." Veterinární Medicína 61, No. 9 (2016): 524–27. http://dx.doi.org/10.17221/1/2016-vetmed.

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This paper describes clinical experiences with the use of shape memory nickel-titanium (NiTi) clips in gastrointestinal surgery in dogs. Side-to-side small bowel anastomosis was performed in eight dogs where intestinal continuity had to be restored after bowel resection. Billroth’s operation I was performed in one case. Compression anastomosis clips with two-way shape memory were used in all surgical procedures. Intestinal and gastrointestinal anastomoses involving shape memory clips were effective in all patients. Anastomotic leaks were not observed, and all clips were expelled 5–7 days after surgery. The outcomes of surgical procedures performed on canine patients with the use of shape memory NiTi clips indicate that sutureless compression anastomosis is a safe, effective and simple method of restoring gastrointestinal continuity, which can be widely applied in veterinary practice.
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2

Полуэктов and V. Poluektov. "Treatment of patients with anastomotic stricture scar gastrointestinal (scientific report)." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 0. http://dx.doi.org/10.12737/7372.

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A large number of operations on the gastrointestinal anastomoses various superimposed ends. Unfortunately, in some cases, the healing anastomosis stricture formation ends. Over the past years there have been an effective minimally invasive treatments anastomotic stricture based on the violent, mechanical expansion narrowing of the anastomosis. And when they are used may occur serious complications.
 This article presents the different ways to improve treatments for anastomotic stricture of the gastrointes-tinal tract by means of endoscopic tools that will improve the safety of these methods.
 The results of treatment of cicatricial strictures anastomoses on advanced techniques in 42 patients.
 In particular, in all patients, the technique used to ensure the removal of scar strictures. In one case, prob-ing, there was bleeding from the area of the anastomosis, which was verified during the procedure, allowing for a timely endoscopic hemostasis with a favorable outcome. Other complications.
 The article concluded that improved methods of treating scar stricture of anastomosis of the gastrointes-tinal tract, applied in the clinic are highly have a minimum number of complications and are the method of choice in this pathology.
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3

Tang, Ze, Hongfei Cai, and Youbin Cui. "Influence of Early Postoperative Feeding in Gastrointestinal Anastomotic Fistula Formation and Healing Time in Rabbits." BioMed Research International 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/8258096.

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Objectives. To determine whether early postoperative feeding attenuates the inhibitory effects of intestinal anastomosis in rabbits. Methods. After undergoing gastrointestinal anastomosis, 48 rabbits were randomly divided into experimental and control groups. The rabbits in the experimental group were fed a liquid diet beginning 24 h postoperatively, while the control rabbits received only total parenteral nutrition after the operation. Exploratory laparotomies were performed on four rabbits in each group 3, 5, 7, 10, and 15 days postoperatively, and the healing rate of the anastomosis, anastomotic bursting pressure, anastomotic breaking strength, and hydroxyproline content at the anastomosis were determined. Results. The anastomoses healed in 91.6% (22/24) of the control group and 95.8% (23/24) of the experimental group. The anastomotic bursting pressure decreased remarkably in both groups 3 days postoperatively, reaching the lowest value. The anastomotic breaking strength did not differ between the two groups 3 days postoperatively, when both reached their lowest points, and both groups increased markedly and peaked 10 days postoperatively. The hydroxyproline content of the anastomosis was slightly lower in the experimental group 3 days postoperatively, although both groups peaked 7 days postoperatively. Conclusions. Early postoperative feeding does not increase the anastomosis healing time or rate of gastrointestinal anastomosis leakage.
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4

Cossu, Maria Laura, Massimiliano Coppola, Enrico Fais, et al. "The Use of the Valtrac Ring in the Upper and Lower Gastrointestinal Tract, for Single, Double, and Triple Anastomoses: A Report of 50 Cases." American Surgeon 66, no. 8 (2000): 759–62. http://dx.doi.org/10.1177/000313480006600815.

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The Valtrac biofragmentable anastomotic ring (V-BAR) technique has been widely used in clinical practice, particularly in anastomoses of the colon. The success of this method encouraged some surgeons to use it also in anastomosis of the small intestine. We are convinced that the method can be used successfully also in anastomosis of the small intestine and the upper gastrointestinal tract, particularly in cases of technically difficult and high-risk anastomoses. Between 1995 and 1998, we used the V-BAR in 35 patients, performing a total of 50 anastomoses. In 13 patients a double anastomosis was created in the same operation, and in one patient a triple anastomosis was created. In all we performed one end-to-end esophagojejunostomy, one gastrojejunostomy, six gastroileostomies, two duodenojejunal anastomoses, 13 end-to-end duodenoileostomies, one jejuno-jejunal anastomosis, 18 end-to-side ileoileal anastomoses, one ileocolic anastomosis, and seven colocolic anastomoses. Follow-up at between 2 and 36 months showed good overall results with regard to resumption of intestinal transit and canalization, even in those cases in which a double and triple suture was performed using the Valtrac ring. In our experience, the V-BAR can be used in upper gastrointestinal surgery with excellent results. Compared with manual sutures, the ring allows better and faster resumption of transit and canalization.
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5

Md Hakim Mia, Shib Shankar Kuiri, Kanchan Kundu, and Sayan Chakrabarty. "Prospective observational comparative study of outcomes between single-layer versus double-layer gastrointestinal anastomosis." Asian Journal of Medical Sciences 14, no. 10 (2023): 263–70. http://dx.doi.org/10.3126/ajms.v14i10.54858.

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Background: In elective gastric surgeries, gastrojejunostomy is the most common anastomosis being done in both benign and malignant conditions. Anastomotic leak, bleeding, wound infection, and anastomotic stricture are important complications associated with intestinal anastomosis. Both double-layer and single-layer anastomosis are well-established techniques for gastrojejunostomy. Till now, there are no definite concluding findings that determine the suitability of either technique. Aims and Objectives: To compare the utility of single-layer gastrointestinal anastomosis versus double-layer gastrointestinal anastomosis in terms of post-operative outcome. Materials and Methods: A hospital-based prospective comparative study was conducted in the department of general surgery BSMCH with a time frame of about 1/2 years. A total no of 52 patients of the adult age group (18–80 years) admitted in the department of general surgery underwent gastrointestinal anastomosis has been studied. Results: Twenty-six (50%) patients underwent single-layer gastrointestinal anastomosis. The rest 26 (50%) underwent double-layer anastomosis. There is no statistically significant difference between these two groups in terms of post-operative nausea vomiting (P=0.73419), wound infection (P=0.385332), anastomotic leak (P=0.552003), and pelvic abscess (P=0.4924). However, the duration of surgery (P<0.0001) and hospital stay (P=0.0179) was significantly less in single-layer gastrointestinal anastomosis. Conclusion: Double-layer gastrointestinal anastomosis offers no definite advantage over single-layer anastomosis in terms of post-operative complications. Considering the duration of the anastomosis procedure and hospital stay, single-layer gastrointestinal anastomosis may prove the optimal choice in most surgical situations.
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6

Salem, Mohamed Hasson, Othman Mohammed A. Nasser, and Awadh Hudeel. "Early oral feeding after gastrointestinal anastomosis." University of Aden Journal of Natural and Applied Sciences 26, no. 1 (2022): 105–13. http://dx.doi.org/10.47372/uajnas.2022.n1.a10.

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To allow healing of the anastomotic site, nil-by-mouth is widely practiced for several days after resection and anastomosis of gastrointestinal. This study determines the feasibility and safety of early oral feeding following gastrointestinal resections and anastomoses. This prospective study included consecutive patients who underwent gastrointestinal resection from June 2016 to June 2021. These patients divided into two groups, according to their postoperative feeding protocol. The early oral feeding group received oral diet on the first postoperative day, while the late oral feeding group were started on oral feeding after the passage of flatus. No significant differences were found in tolerance to oral feeding (p = 0.230) and the postoperative complications (p = 0.253) between the two groups. Compared with the late oral feeding group, time to first flatus, bowel movement and length of postoperative hospital stay were significantly shorter in the early oral feeding group (for all p = 0.002). Early oral feeding after gastrointestinal anastomosis is feasible and safe.
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7

R., Banurekha, Sadasivam S., and Sathyamoorthy K. "Hand sewn versus stapler anastomosis in elective gastro intestinal surgeries." International Surgery Journal 4, no. 7 (2017): 2316. http://dx.doi.org/10.18203/2349-2902.isj20172789.

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Background: The technique for intestinal anastomosis in elective gastrointestinal surgeries depends on site, bowel calibre and underlying disease. The decision to choose hand sewn or stapler anastomosis depends on surgical experience and preference. The objective of this study was to study the outcome of hand sewn anastomosis compared with stapler anastomosis in elective gastrointestinal surgeries.Methods: Retrospective comparative study was conducted in surgical wards of a tertiary referral hospital from July’2013 to June’2016. Data analysed with independent samples T-test to compare mean values between methods and Chi-square tests used to compare proportion of the two values.Results: Significant difference in duration of procedure, return of bowel sounds, starting of oral feeds, hospitalization days, return to work noted in stapler anastomosis compared with hand sewn anastomosis in subtotal gastrectomy and gastrojejunostomy. No difference in appearance of bowel sounds in right hemicolectomy and other resection and anastomoses group, no difference in return to work in right hemicolectomy group, no difference in starting of oral feeds in low anterior resection group. Other parameters were statistically significant in right hemicolectomy, low anterior resection and other resection and anastomosis groups. No significant difference observed in anastomotic leak between hand sewn and stapler methods. There was no mortality in stapler group.Conclusions: Stapler method significantly reduces duration of surgery, has early recovery with less mortality. Stapling is quick to perform in inaccessible situations like low colorectal anastomosis. Stapler anastomosis can be used safely and effectively in elective gastrointestinal surgeries.
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8

Srinivas, L., B. Venkatesh, and Samir Ahmad. "A study of factors leading to post-operative leaks following bowel anastomosis." International Surgery Journal 5, no. 11 (2018): 3510. http://dx.doi.org/10.18203/2349-2902.isj20184218.

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Background: Intestinal anastomosis is one of the most commonly performed procedures, especially in the emergency setting and is also in the elective setting when resection is carried out for benign or malignant lesion of the gastrointestinal tract. Anastomotic leakage is a potentially disastrous complication, which can lead to sepsis and abdominal catastrophe. The aim of the study is to determine factors leading to post-operative leaks in gastrointestinal surgeries involving different kinds of anastomosis and to determine the role of parameters such as pre-operative hemoglobin, serum albumin, indication for surgery, degree of contamination, type of anastomosis, technical variations and postoperative management in anastomotic leaks. We also aim to determine the morbidity and mortality variation and to study the various presentations of anastomotic leak in the patient group as well.Methods: A prospective study was conducted from December 2015 till the end of august 2017 at Prathima Institute of Medical Sciences, Karimnagar. All patients undergoing gastrointestinal anastomosis electively and as an emergency procedure were included in this study. The total number of cases studied is 60.Results: Out of the 60 cases in this study, 49 cases were done electively, and 11 cases were done on an emergency basis. Anastomotic leaks occurred most in emergency cases (27.27%). Among 5 patients, (71.42%) leaks were managed conservatively and rest required intervention. There was increased death rate in patients with leak. Leaks occurred maximum in jejunoileal anastomosis. Most common organ involved was esophagus (28.57%).Conclusions: Anastomotic leaks are a common complication following all types of gastrointestinal anastomosis. It is believed, hypoalbuminemia hinders anastomotic healing. Surgeries indicated in emergency situation carried increased risk of operative leaks in post-operative period.
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9

Sai, K. Lohit, and C. Sugumar. "A comparative study of single layer extra mucosal versus conventional double layer anastomosis of intestines in elective and emergency laparotomy." International Surgery Journal 7, no. 1 (2019): 184. http://dx.doi.org/10.18203/2349-2902.isj20195966.

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Background: Gastrointestinal anastomosis has been a part of research since decades and is one of the key skills in surgeon’s armamentarium. This study compared the outcome of single layer anastomosis with double layer anastomosis.Methods: The study was designed as a prospective comparative study and 29 cases were included in the study during December 2016 to September 2017, who consented for being part of the study. Patients were alternatively allotted into the either group. Group A underwent single layer anastomosis and Group B underwent double layer anastomosis. Outcome parameters were analysed in the form of ‘duration required to perform anastomoses, ‘duration of hospital stay’ and ‘dnastomotic leak.Results: Mean duration required to perform anastomosis in Group A is 21.64±1.60 minutes and in Group B is 29.6±2.02 minutes. The difference between the mean duration required for anastomosis between the two groups were statistically significant (p<0.005). Mean duration of hospital stay in Group A was 12.35±1.72 days and Group B was 12±2.44 days (difference was statistically insignificant), 3 (10%) cases in Group A and 2 (6.8 %) cases in Group B developed anastomotic leak and the difference was statistically insignificant.Conclusions: Our study concluded that there is statistically significant difference between the single layer anastomosis and double layer anastomosis in terms of time taken to perform anastomosis, however there is no difference in postoperative anastomotic leak and duration of hospital stay.
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10

Simmons, Jon D., Joseph W. Gunter, Justin D. Manley, David E. Sawaya, and Christopher J. Blewett. "Stapled Intestinal Anastomosis in Neonates: Validation of Safety and Efficacy." American Surgeon 76, no. 6 (2010): 644–46. http://dx.doi.org/10.1177/000313481007600632.

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The safety and effectiveness of a stapled intestinal anastomosis in adults and children is well documented. However, the role of this technique in neonates is not well validated. We report our experience with stapled intestinal anastomoses in the neonate at the University of Mississippi Medical Center. All patients from the neonatal intensive care unit who had a stapled intestinal anastomosis between February 2007 and May 2008 were identified. A stapled side-to-side functional end-to-end intestinal anastomosis was performed in all patients using a gastrointestinal anastomosis stapler. Demographic, management, and outcome data were collected via chart review. Variables collected included: birth weight, estimated gestational age at birth and surgery, weight at surgery, the use of vasopressors, associated diagnoses, location of the anastomosis, and postoperative clinic visits. A total of 18 patients were identified during the study period. Nine had small bowel to small bowel, eight had ileum to colon, and one had a colon to colon anastomosis. The average weight at time of operation was 2.8 kilograms (Kg) and the average estimated gestational age at surgery was 38.7 weeks. The only complication reported was a partial small bowel obstruction on postoperative day 12, which was successfully treated nonoperatively. Two patients died from problems not associated with the anastomosis. There were no anastomotic leaks or strictures. The literature regarding the use of stapled bowel anastomoses in neonates is scant. Stapled intestinal anastomoses can be performed safely in neonates without a high rate of complication. The long term effects of stapled intestinal anastomoses in the neonate are unknown. Future areas of interest would include effects on postoperative feeding and operative time.
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11

Patel, Dr Shaishav V., Dr Kalpit R. Suthar, Dr Dhruv N. Shah, Dr Hitesh Kumar Tourani, Dr Ashwin P. Godbole, and Dr Yuvrajsinh Rathod. "A Comparative Study of Stapler Versus Handsewn Gastrointestinal Anastomosis." BJKines National Journal of Basic & Applied Sciences 14, no. 1 (2022): 28–32. http://dx.doi.org/10.56018/bjkines2022064.

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Background: In gastro intestinal surgery after resection of bowel loops, anastomosis of the bowel loops is the central part. Stapler technique, commonly used by many of the surgeons is more useful than the hand sewn anastomosis for safety, easy accessibility, duration of procedure, efficiency. This study compares the hand sewn anastomosis with stapler Anastomosis. The purpose of the presentation is to compare the feasibility and outcome of stapler and hand sewn anastomosis in gastro intestinal surgeries. Material & Method: This study was conducted in the department of surgery of our hospital between the groups of hand sewn and stapler anastomosis gastro intestinal surgeries conducted by open technique in period from January 2021 to September 2021. Results: Various parameters like operative time, hospital stay, and post op day of starting oral diet, post op day of appearance of bowel sound, anastomotic leak, time taken to return to work and mortality were compared. Conclusion: Results of this study were comparable to many studies done previously which showed there was not much significant difference in post op outcomes after hand sewn or stapled technique of gastrointestinal anastomosis. Key-words: Anastomosis, stapler, handsewn
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12

Uppal, Abhineet, and Alessio Pigazzi. "New Technologies to Prevent Anastomotic Leak." Clinics in Colon and Rectal Surgery 34, no. 06 (2021): 379–84. http://dx.doi.org/10.1055/s-0041-1735268.

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AbstractLeaks from anastomoses can be a serious complication of any gastrointestinal resection. Leaks lead to increased morbidity, delayed postoperative recovery, and potential delays in adjuvant treatment in cancer cases. Prevention of anastomotic leak has been an area of ongoing research for decades. Methods of assessing bowel perfusion have been developed that may provide forewarning of anastomotic compromise. Physical reinforcement of the anastomosis with buttressing material is an available method employed with the goal of preventing leaks. Liquid-based sealants have also been explored. Lastly, interactions between the gut microbiome and anastomotic healing have been investigated as a mean of manipulating the microenvironment to reduce leak rates. Though no single technology has been successful in eliminating leaks, an understanding of these developing fields will be important for all surgeons who operate on the gastrointestinal tract.
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13

Cortina, Chandler S., Gillian C. Alex, Kristin N. Vercillo, et al. "Longer Operative Time and Intraoperative Blood Transfusion are Associated with Postoperative Anastomotic Leak after Lower Gastrointestinal Surgery." American Surgeon 85, no. 2 (2019): 136–41. http://dx.doi.org/10.1177/000313481908500218.

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Anastomotic leak after lower gastrointestinal surgery is a complication with potential for high morbidity, mortality, and increased costs. A single-institution retrospective chart review was performed on all patients who underwent lower gastrointestinal surgery between June 2009 and June 2013. Fifty-seven variables were included in our analysis and their association with postoperative anastomotic leak was examined. Nine hundred fifty-two patients underwent 983 lower gastrointestinal anastomoses with an overall leak rate in this series of 6 per cent. Type of intestinal anastomosis created (P < 0.00005), operative indication (P < 0.015), operation performed (P < 0.014), intraoperative blood transfusion (P < 0.017), and intraoperative surgical drain placement (P < 0.022) were all predictive of anastomotic leak. Anastomotic leak rate increased by 1.3 times for every additional hour in the operating room after three hours. Both increasing operation time and intraoperative blood transfusions were associated with an increased rate of anastomotic leak. When operative time extends beyond three hours or in those cases were blood transfusions are given, surgeons should consider taking steps to minimize the risks of a potential anastomotic leak.
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14

Belbase, Narayan Prasad, Aditya Jalan, Bhupendra Nath Patowary, and Sujit Kumar. "A comparative prospective study of handsewn versus stapled anastomosis in lower gastrointestinal surgeries." Journal of College of Medical Sciences-Nepal 13, no. 4 (2017): 378–82. http://dx.doi.org/10.3126/jcmsn.v13i4.17165.

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Background & Objectives: Though abdominal surgery has been practiced for many centuries, the optimal technique for anastomosis of small bowel and large bowel remains controversial. This study was conducted with objective to compare the outcome of stapled and handsewn technique of anastomosis of the lower gastrointestinal tract.Materials & Methods: This prospective study was done in the Department of General Surgery and Surgical Gastroenterology, College of Medical Sciences, Bharatpur in the period between 1st October 2014 to 30th September 2015. A total of 50 patients who underwent resection and anastomosis for various conditions of small bowel and large bowel were alternatively placed in handsewn and stapled group. Both the groups were compared in terms of mean time required to perform the intestinal anastomosis, mean operating time, postoperative complications like anastomotic leak rate and wound infection rate, and the time of postoperative hospital stay.Results: The mean duration to perform the intestinal anastomosis was 32.04±4.51 minutes in the handsewn group and 11.00±1.91 minutes in the stapled group(p<0.001).The mean operative time was 147.12±20.91 minutes in the handsewn group versus 132.52 ± 15.71 minutes in the stapled group(p<0.05). The mean duration of postoperative hospital stay was 9.04±2.77 days in the handsewn group versus 8.44 ± 2.32 days in the stapled group (p>0.05). There was no significant difference in the anastomotic leak rate and surgical site infection rate among the two groups.Conclusion: Stapling technique can significantly reduce the time for the anastomotic procedure and also the duration of the operation. However, there was no difference in the rate of anastomotic leak and wound infection between the handsewn and stapled anastomosis. Therefore, stapled anastomosis can be considered a better option over handsewn bowel anastomosis.
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15

Bashirov, S. R., S. S. Klokov, V. A. Korepanov, D. V. Krinitsky, N. S. Rudaya, and M. B. Arzhanik. "Universal intestinal suture in rehabilitation of patients with single-layer anastomoses after elective upper gastrointestinal tract surgery." Pirogov Russian Journal of Surgery, no. 1 (February 4, 2025): 37. https://doi.org/10.17116/hirurgia202501137.

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Objective. To evaluate universal intestinal suture in rehabilitation of patients with single-row anastomoses after elective upper gastrointestinal tract surgery. Material and methods. A single-center study included 142 patients over 8-year period. There were 72 (50.7%) pancreaticoduodenectomies and 70 (49.3%) gastric resections and gastrectomies. The rehabilitation program included single-layer anastomoses using universal intestinal suture, intestinal drainage for decompression and enteral nutrition, therapeutic and diagnostic endoscopy to stimulate motor evacuation function, patency of anastomoses and assessment of anastomositis. Results. Intestinal drainage for decompression and enteral nutrition was used for 6 (4; 7) days after surgery. Intraluminal endoscopy was performed after 9 (7; 11) days. In patients with anastomositis grade 0 (26.5%) and 1 (62.4%), we observed minimal inflammation along intestinal suture line (mean hospital-stay 16 (13; 20) days). In patients with anastomositis grade 2 (8.5%) and 3 (2.6%), we observed surface erosions and ulcers in the anastomosis zone (mean postoperative hospital-stay 20 (16; 27) days). Postoperative complications unrelated to anastomoses were diagnosed in 17.6% of cases; 12% of patients underwent redo surgery. Mortality rate was 2.8%. Conclusion. Universal intestinal suture in rehabilitation of patients with single-layer anastomoses contributed to uncomplicated healing of anastomoses in 88.9% of patients with anastomositis grade 0—1 and reduced the incidence of anastomositis grade 2—3 to 11.1%, as well as hospital-stay after elective upper gastrointestinal tract surgery.
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Fatyushina, O. A., M. M. Soloviev, E. A. Avdoshina, T. A. Tomova, and A. M. Fatyushina. "Compression anastomoses in the surgical treatment of patients with diseases of the gastrointestinal tract." Issues of Reconstructive and Plastic Surgery 25, no. 2 (2022): 120–27. http://dx.doi.org/10.52581/1814-1471/81/13.

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The results of a study of titanium nickelide devices used for the formation of compression anastomoses in patients with digestive system diseases and describes the techniques of compression fistula formation using these devices has been presented. Besides, the paper presents clinical experience in the formation of anastomoses between the organs of gastrointestinal tract for the treatment of 96 patients with various pathologies of digestive organs. 116 compression anastomoses were applied in our clinic. Anastomotic dehiscence was found in three cases (2,6%) which are described in details in the article. In all patients, the devices evacuated from the digestive tract in a natural way for 14 days. Fibrotic scope examination performed after an operation showed that created anastomoses corresponded to the dimensions of used structures. A soft scar by primary healing type was formed on the parts with compression anastomosis. Using titanium nickelide devices for the formation of compression anastomoses between the gastrointestinal organs will improve the quality of fistula formation, reduce mortality and postoperative complications.
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Limbu, Yugal, Prashanta Pudasaini, Sujan Regmee, et al. "Indocyanine green fluorescence imaging in gastrointestinal surgery." Journal of Kathmandu Medical College 12, no. 2 (2023): 80–86. http://dx.doi.org/10.3126/jkmc.v12i2.45509.

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Background: Prevention of post-operative anastomotic leak (AL) is significant challenge for surgeons, with roughly half of all AL cases linked to insufficient vascular supply, often undetectable during anastomosis. Recently, indocyanine green fluorescence (ICG) emerged as promising tool in visceral surgery due to its low cost, ease of use, wide availability, and low toxicity. In gastrointestinal surgery, ICG is primarily used for real-time intraoperative angiography, allowing surgeons to assess anastomotic stumps' perfusion before and after procedure. Objectives: To assess efficacy of ICG as an adjunct in preventing AL. Methods: This descriptive study conducted after ethical approval at Kathmandu Medical College Teaching Hospital from 2022 February 15 to 2023 January 30 included 111 patients enrolled via convenience sampling. During operation, surgeon used ICG fluorescence angiography on patients to determine perfusion status, which allowed for evaluation of transection line and post-anastomotic viability. Data were entered in Microsoft Excel sheet 2019 and descriptive analysis done regarding demographic data, changes in the transection line, and post-operative anastomotic leaks. Results: Total 111 patients with age 55.41 ± 13.63 years and male-female ratio of 2:1 participated in this study. ICG use resulted in changes to proximal resection margin for five (4.5%) patients. Clinical judgment and ICG fluorescence imaging showed a difference in bowel transection line of 0.5-1.5 cm. None of the patients who underwent proximal resection margin revision with the assistance of ICG experienced post-operative anastomotic leaks. Conclusion: ICG fluorescence can be used as an adjunct in determining the viability of anastomosis and prevent post-operative anastomosis leak.
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Niejadlik, Szymon, and Dariusz Sokołowski. "Effects of octreotide pharmacotherapy in the treatment of complicated perforation of retroperitoneal duodenal ulcer." Lekarz Wojskowy 102, no. 3 (2024): 221–24. http://dx.doi.org/10.53301/lw/186364.

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Duodenal ulcer is a defect in the mucosa. The main aetiological factors are <i>H. pylori</i> infection, nonsteroidal anti-inflammatory drugs, genetic factors, and nicotinism. Statistics confirm that perforation is a significant and potentially life-threatening ulcer complication in the Polish population. Octreotide is a somatostatin derivative that works by inhibiting the release of proteins of the gastrointestinal-pancreatic system. It is indicated in acromegaly, hormonally active gastrointestinal tumours, and oesophageal variceal bleeding. It can be used to reduce bile secretion and slow down gallbladder motility. The material for this review paper was a case of duodenal perforation in a woman aged 63 years. Octreotide used in the treatment of a difficult-to-heal anastomosis improved the patient’s local and general condition, and led to the closure of the anastomosis. Despite the significant number of circumstances leading to the patient’s life-threatening condition in the course of the perforation, there were also factors that positively influenced the treatment outcome. The most important of these was the use of octreotide to increase the chances of healing of the intestinal-intestinal anastomosis in the area of influence of digestive enzymes. The conclusions drawn from this case suggest that octreotide can be used in the treatment of non-healing, properly performed gastrointestinal anastomoses. More effective prophylaxis, early diagnosis of peptic ulcer disease, and increasing access to endoscopy are known to reduce the number of perforation cases. Importantly, there are cases of perforations that can be lifethreatening for the patient even in the course of anastomotic dissections of properly performed surgical procedures. Octreotide should be considered in the management of complicated and extreme perforations. This paper describes the possibility of using octreotide as a pharmacotherapy to increase the chances of gastrointestinal anastomosis healing in cases involving complicated duodenal perforations.
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Liu, Pi-Chu, Zhi-Wei Jiang, Xiao-Lin Zhu, et al. "Compression anastomosis clip for gastrointestinal anastomosis." World Journal of Gastroenterology 14, no. 31 (2008): 4938. http://dx.doi.org/10.3748/wjg.14.4938.

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20

Kopelman, Doron, Ossama A. Hatoum, Boaz Kimmel, et al. "Compression gastrointestinal anastomosis." Expert Review of Medical Devices 4, no. 6 (2007): 821–28. http://dx.doi.org/10.1586/17434440.4.6.821.

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21

Sandip, Kumar Bharai, Sindhal Mineshkumar, and M. Aanandaka Priyanka. "A Comparative Study of Hand Sewn versus Stapler Anastomosis in Elective Gastrointestinal Surgeries." International Journal of Toxicological and Pharmacological Research 14, no. 3 (2024): 201–6. https://doi.org/10.5281/zenodo.10963392.

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<strong>Introduction:&nbsp;&nbsp;</strong>In the realm of gastrointestinal surgeries, the choice between hand-sewn and stapler anastomosis techniques remains a critical decision for surgeons. Intestinal anastomosis, which establishes communication between segments of the intestine, plays a pivotal role in restoring continuity post-surgery. While hand-sewn anastomosis has long been the conventional approach, stapler devices have emerged as an alternative method offering enhanced precision, reduced operative time, and potentially improved postoperative outcomes. This study aims to provide a comparative analysis of hand-sewn versus stapler anastomosis in elective gastrointestinal surgeries, shedding light on their respective advantages and limitations.&nbsp;<strong>Material and Methods:</strong>&nbsp;The study, conducted at the Department of General Surgery, Shree M.P. Shah Govt. Medical College, Jamnagar, spanned 12 months and focused on patients undergoing gastrointestinal surgeries necessitating bowel anastomosis. Patients were categorized into two groups: Group A underwent hand-sewn anastomosis using various sutures, while Group B received stapler anastomosis using different stapling devices. Inclusion criteria comprised patients aged 18 to 80 years undergoing elective gastrointestinal surgeries with written consent. Patients were assessed for various parameters such as procedure time, return of bowel sounds, oral feeding resumption, postoperative stay, and complications. Statistical analysis employed independent samples T-Test and Chi-Square tests for comparison, ensuring robust evaluation of outcomes and techniques.&nbsp;<strong>Results:&nbsp;</strong>The study encompassed 40 cases of resection and anastomosis, with 20 patients undergoing hand-sewn anastomosis and the remaining 20 undergoing stapler anastomosis. The observational comparative design allowed for a detailed examination of the outcomes. Among these cases, 10 involved gastrojejunostomy, 14 involved jejuno-jejunostomy, and 16 involved ileo-colic (right hemicolectomy) procedures. Analysis revealed a trend favoring stapler anastomosis, showcasing shorter operation times, reduced hospital stays, and earlier return to work compared to hand-sewn anastomosis across all three surgery groups. Stapler anastomosis demonstrated advantages such as reduced operation times (ranging from 1.5 to 2.00 hours), shorter hospital stays (ranging from 8.00 to 8.00 days), and earlier return to work (ranging from 2.9 to 4.25 months) in comparison to hand-sewn techniques. Additionally, stapler anastomosis exhibited fewer complications, including lower rates of anastomotic leaks and mortality, highlighting its potential superiority in gastrointestinal surgery.&nbsp;<strong>Conclusion:</strong> Our study reveals stapler anastomosis as superior to hand-sewn techniques in gastrointestinal surgeries, offering benefits such as reduced tissue injury, shorter operating times, and quicker recovery.
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Sarkar, Amarendra Nath, Partha Pratim Deb, and Satyajit Naskar. "A Comparative Study between Stapler and Hand Sewn Anastomosis in Elective Gastrointestinal Surgery in a Tertiary Care Centre." Scholars Journal of Applied Medical Sciences 12, no. 05 (2024): 644–47. http://dx.doi.org/10.36347/sjams.2024.v12i05.022.

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An intestinal anastomosis becomes necessary when a segment of the gastrointestinal tract is resected for benign or malignant indications and gastrointestinal continuity needs to be restored. The oldest method to close intestinal wound was described by the Indian physician Sushruta, 800 years before Christ, who used the jaws of ants to hold the wound margins together. The introduction of staplers in recent decades have enabled to construct a safe anastomosis in places difficult to reach for conventional suture techniques. There are several studies which showed that there are no such differences in conventional handsewn and stapler anastomosis technique in elective gastrointestinal surgeries except the duration of operation is less in stapler anastomosis technique. In the present study, three types of gastrointestinal anastomosis (gastrectomy &amp; gastrojejunostomy, right hemicolectomy &amp; ileocolic anastomosis and anterior resection &amp; rectocolic anastomosis) were taken and all 68 patients after these operative procedures were divided into two groups (gr A handsewn and gr B stapler). They were compared by the parameters like duration of procedure, appearance of bowel sounds in postoperative period, anastomotic leak and duration of hospital stay. Regarding duration of operative procedure, the mean duration of gastrectomy and gastrojejunostomy for gr A was 166 mins and for gr B was 144 mins, the mean duration of right hemicolectomy and ileocolic anastomosis for gr A was 143 mins and for gr B was 125 mins, the mean duration of anterior resection and rectocolic anastomosis for gr A was 149 mins and for gr B was 131 mins. It signifies that gr B or stapler anastomosis required less time and this value was statistically significant (p &lt;0.0001). There was no statistically significant difference regarding the appearance of bowel sounds, starting of oral feeding and hospital stay in the postoperative periods. We conclude that there was reduction in operative time in patients ......
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Wiggins, T., MS Majid, SR Markar, J. Loy, S. Agrawal, and Y. Koak. "Benefits of barbed suture utilisation in gastrointestinal anastomosis: a systematic review and meta-analysis." Annals of The Royal College of Surgeons of England 102, no. 2 (2020): 153–59. http://dx.doi.org/10.1308/rcsann.2019.0106.

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Introduction Anastomosis formation constitutes a critical aspect of many gastrointestinal procedures. Barbed suture materials have been adopted by some surgeons to assist in this task. This systematic review and meta-analysis compares the safety and efficacy of barbed suture material for anastomosis formation compared with standard suture materials. Methods An electronic search of Embase, Medline, Web of Science and Cochrane databases was performed. Weighted mean differences were calculated for effect size of barbed suture material compared with standard material on continuous variables and pooled odds ratios were calculated for discrete variables. Findings There were nine studies included. Barbed suture material was associated with a significant reduction in overall operative time (WMD: -12.87 (95% CI = -20.16 to -5.58) (P = 0.0005)) and anastomosis time (WMD: -4.28 (95% CI = -6.80 to -1.75) (P = 0.0009)). There was no difference in rates of anastomotic leak (POR: 1.24 (95% CI = 0.89 to 1.71) (P = 0.19)), anastomotic bleeding (POR: 0.80 (95% CI = 0.29 to 2.16) (P = 0.41)), or anastomotic stricture (POR: 0.72 (95% CI = 0.21 to 2.41) (P = 0.59)). Conclusions Use of barbed sutures for gastrointestinal anastomosis appears to be associated with shorter overall operative times. There was no difference in rates of complications (including anastomotic leak, bleeding or stricture) compared with standard suture materials.
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Anandan, Prem Kumar, Mir Mohammed Noorul Hassan, and Mebin Mathew. "Pre-operative hypoalbuminemia is a major risk factor for anastomotic leak in emergency gastrointestinal resection and anastomosis." International Surgery Journal 4, no. 4 (2017): 1405. http://dx.doi.org/10.18203/2349-2902.isj20171151.

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Background: The serum albumin level is one of several clinical parameters of the status of general health. Hypoalbuminemia is known to be associated with delayed wound healing. The hypoalbuminemic state interferes with the normal functioning of the gastrointestinal tract. This study evaluates the relation of pre-operative albumin level and the risk for anastomotic leak in emergency gastrointestinal resection and anastomosis.Methods: A total of 112cases that meet the inclusion and exclusion criteria are included from Bangalore Medical College and Research Institute, Karnataka, India for a duration of 18 months November 2014 to October 2016.51 cases belonged to the stapled group and 61 cases belonged to the sutured group. Anastomosis using the two techniques, stapled and hand sewn anastomosis are evaluated separately.Results: The relation of pre-operative serum albumin and anastomotic leak is analysed in each study group separately and found that a pre-operative albumin of &lt;3.5gm/dl is significantly associated with post-operative anastomotic leak, with a p-value of 0.0418 (p&lt;0.05) in stapled anastomosis group and a p-value of 0.0357 (p&lt;0.05) in hand sewn anastomosis group.Conclusions: Pre-operative albumin of &lt;3.5gm/dl is significantly associated with post-operative anastomotic leak in both the groups, irrespective of the technique adopted.
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Dambaev, G. Ts, V. E. Gunther, O. A. Fatushina, et al. "Compression Anastomoses Formation on the Digestive Tract Organs with Using TiNi Devices." KnE Materials Science 2, no. 1 (2017): 176. http://dx.doi.org/10.18502/kms.v2i1.794.

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The article contains the results of a study of nickelid titanium devices used for the formation of compression anastomoses in patients with digestive system diseases and describes the techniques of compression fistula formation using these devices. Besides, the article presents clinical experience in the formation of anastomoses between the organs of gastrointestinal tract for the treatment of eighty-seven patients with various pathologies of digestive organs. One hundred and nine compression anastomoses were applied in our clinic. Anastomotic dehiscence was found in three cases (2,7%) which are described in details in the article. In all patients, the devices evacuated from the digestive tract in a natural way. The average period of device rejection accounted for 14 days. Fibrotic scope examination performed after an operation showed that created anastomoses corresponded to the dimensions of used structures. A soft scar by primary healing type was formed on the parts with compression anastomosis. Using nickelid titanium devices for the formation of compression anastomoses between the gastrointestinal organs will improve the quality of fistula formation, reduce mortality and postoperative complications.
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Nichkaode, Prabhat B., and Aditya Parakh. "Stapling devices: comparative study of stapled versus conventional hand sewn anastomosis in elective gastrointestinal surgery." International Surgery Journal 4, no. 9 (2017): 2937. http://dx.doi.org/10.18203/2349-2902.isj20173874.

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Background: Gastro intestinal anastomosis is a commonly performed surgical procedure to establish communication between two formerly distant portions of the bowel since the era of Sushruta. Various methods of intestinal anastomosis were followed. Stapling devices are now the newer alternative to conventional hand sewn method of anastomosis. It is stated that a key to a successful anastomosis is accurate anastomosis of two viable ends of the bowel without tension, with good vascularity. Because of the use of staplers technical failures is a rarity, anastomosis is more consistent, and can be used at difficult locations.Methods: A total of 68 cases which met the inclusion and exclusion criteria were included in this hospital based prospective comparative study. The study population included patients who underwent elective gastrointestinal surgeries. The subjects were allocated into two groups according to the type of anastomosis, hand sewn and stapler. Both hand sewn and stapled anastomosis were further divided into three sub-groups according to the anatomical site of anastomosis viz esophageal, gastrojejunal and colorectal. Outcome factors: anastomotic integrity, duration of operation, return of bowel activity, hospital stay.Results: A total of 68 patients with malignant or benign condition of bowel and oesophagus, requiring anastomosis were allocated in study group of GI staplers and control group of conventional hand sewn technique. Out of 68 cases there were 13 Esophageal anastomosis, 21 gastrojejunostomy and 34 colorectal anastomosis.Conclusions: In present study, we found that stapling technique can significantly reduce the time for anastomotic procedure, less tissue trauma due to less tissue handling, there is early restoration of gastrointestinal function, early resumption of oral feeding and reduced duration of hospital stay which helps ultimately in early return to routine work, importantly staplers can be used at places were hand sewn anastomosis is technically difficult. Technique related complications do not show significant differences which suggest that one can use staplers with same safety and accuracy as sutures.
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Francisco, Javier Cano Palacios, Burciaga Castañeda Ricardo, Kiriathaim Montes Schultz Gustavo, et al. "Mechanical vs Manual Anastomosis." International Journal of Medical Science and Clinical Research Studies 5, no. 04 (2025): 535–38. https://doi.org/10.5281/zenodo.15254657.

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Mechanical and manual anastomosis are two widely used techniques in surgical procedures for joining tissue segments, particularly in gastrointestinal surgery. Mechanical anastomosis, which utilizes stapling devices, offers advantages such as reduced operative time and, in certain procedures, lower rates of complications like anastomotic fistulas and wound infections. However, it has been associated with a higher incidence of anastomotic strictures. In contrast, manual anastomosis provides greater precision and flexibility, making it preferable in cases with poor tissue quality or complex surgical fields, such as pediatric and emergency general surgery patients. The learning curve for manual anastomosis is steep, requiring extensive training and experience. Simulation-based training and mentorship have been shown to improve proficiency and reduce complications such as anastomotic leakage. The choice between mechanical and manual techniques should be based on patient-specific factors, surgical complexity, and surgeon expertise. As surgical advancements continue, further research into optimizing anastomotic techniques will be essential to improving outcomes and minimizing complications.
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Gaurav, Thami, and Garg Akshita. "Outcome of Patients Undergoing Gastrointestinal Anastomosis without Nasogastric Tube Insertion during Elective Surgery." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 626–31. https://doi.org/10.5281/zenodo.14590891.

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<strong>Background:</strong>&nbsp;Routine nasogastric decompression after gastrointestinal surgery has been standard practice since its introduction by Levin in 1921. While traditionally believed to hasten bowel function recovery and prevent complications, recent evidence questions its necessity and suggests potential adverse effects. This study evalu-ates outcomes in patients undergoing gastrointestinal anastomosis without nasogastric tube insertion during elective surgery.&nbsp;<strong>Methods:</strong>&nbsp;A hospital-based prospective study was conducted on 100 patients undergoing elective gastrointesti-nal anastomosis at Kalpana Chawla Government Medical College and Hospital, Karnal, between June 2022 and November 2023. Primary outcomes included time to return of bowel sounds, passage of flatus, and resumption of oral intake. Secondary outcomes included postoperative respiratory tract infections and wound infections.&nbsp;<strong>Results:</strong>&nbsp;Of 100 patients, 93% were male with majority (40%) aged 18-30 years. Mean time for return of bowel sounds was 1.503&plusmn;0.85 days, with 90% returning within first three postoperative days. Passage of flatus oc-curred at mean 2.51&plusmn;1.03 days, with 88% passing flatus between days 1-3. Oral intake resumed at mean 4.80&plusmn;1.42 days. Gastrointestinal symptoms included nausea (49%), vomiting (18%), and abdominal distention (11%). Respiratory complications occurred in 4% patients (pleural effusion). Wound infection was observed in 32% patients (23% minor, 9% major). Anastomotic dehiscence occurred in 6% patients, necessitating nasogas-tric tube insertion. Most procedures were small bowel anastomoses (87%), with ileoileal being most common (78%).&nbsp;<strong>Conclusion:</strong>&nbsp;Selective rather than routine nasogastric tube insertion appears appropriate for patients undergoing elective gastrointestinal anastomosis. This approach offers advantages of patient comfort and earlier return of bowel function while maintaining acceptable complication rates. &nbsp; &nbsp;
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Kyasa, Shiva Kumar, Anil Kumar Bushigampala, Shyam V, and Jadhav Maloth Deepak. "A Clinical Study of the Factors Affecting the Outcome of Intestinal Resection and Anastomosis." International Journal of Toxicological and Pharmacological Research 13, no. 12 (2023): 85–89. https://doi.org/10.5281/zenodo.10981351.

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<strong>Introduction:</strong>&nbsp;Anastomosis refers to a surgical procedure or a natural connection between two tubular structures, such as blood vessels, intestines or other hollow organs. Anastomotic leak is one of the most common and dreaded complications after the surgical procedure of intestinal anastomosis.&nbsp;<strong>Aim and Objective</strong>: To discuss about factors affecting the outcome of intestinal resection and Anastomosis.&nbsp;<strong>Materials and Method:</strong>&nbsp;This was prospective observational study conducted on 75 patients requiring intestinal resection and anastomosis admitted in department of general surgery, Chalmeda Anand Rao Institute of Medical sciences, Karimnagar, for the duration of one year, after approval of institutional ethical committee of our institute, consent from patients and after following inclusion and exclusion criteria.&nbsp;<strong>Results:</strong>&nbsp;75 patients were included in the study, among which nearly 78% of the patients were from the age group of 20-60 years of age, 72% of the study population were male followed by female. 36% of the study population had comorbid condition and 57.3% of the study population underwent elective surgery followed by emergency. Leak were present among 12.96% of the population from male and 19.05%&nbsp; from female, patients with elevated low albumin level leak was observed among 72.72% of the population.&nbsp;<strong>Conclusion:</strong> Levels of serum albumin can be used as a simple, reliable and economical prognostic marker in predicting the outcome of bowel anastomoses. This helps the surgeon in operative decision making as well as explaining the prognosis and operative risk to the patient.
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Arunkumar D, Meghan GS, Shivasharan HN, and Neeta PN. "Efficacy of staplers in comparison with conventional (Hand-Sewn) anastomosis in gastrointestinal surgery – A prospective and randomized study." Asian Journal of Medical Sciences 15, no. 5 (2024): 248–52. http://dx.doi.org/10.3126/ajms.v15i5.62350.

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Background: Gastrointestinal anastomosis is a regularly carried out surgical technique to set up communication between two distant portions of the intestine since the era of Sushruta. There exist different methods of intestinal anastomosis. The newer techniques are Stapling devices over to conventional hand-sewn method of anastomosis. It is proved that a key to a successful anastomosis is accurate anastomosis of two viable ends of the bowel maintaining good vascularity and less tension. Due to consistency, stapler’s can be used at difficult locations. Aims and Objectives: The objective of present study was to compare the outcome of hand-sewn versus stapler anastomosis in elective gastrointestinal surgeries. Materials and Methods: We conducted a prospective and randomized study including 30 study participants each in stapler’s method and hand-sewn method at surgery outpatient department of Kempegouda Institute of Medical Sciences Hospital and Research Center. Results: Stapling procedure took less days to get restored, less time to return of bowel sounds, shorter duration of hospital stays, and less time to resume for oral feeds compared to hand-sewn method and which were statistically significant (P&lt;0.05). Complications such as anastomotic leaks accounted for 3.3% in stapler group and 13.3% in hand-sewn anastomosis, which was not significant statistically. Conclusion: We concluded that time for anastomosis during the procedure, restoration of the gastrointestinal function, oral feeding resumption, and post-operative hospital stay took significantly less time in stapling technique than hand-sewn anastomosis and the staplers looked technically easy compared to hand-sewn method. Complications related to procedure did not show significant differences which helped us to conclude that one can use staplers with similar safety and accuracy as hand suturing method.
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Hashiba, K., A. L. de Paula, S. Wada, et al. "Endoscopic-laparoscopic gastrointestinal anastomosis." Gastroenterology 108, no. 4 (1995): A479. http://dx.doi.org/10.1016/0016-5085(95)26230-x.

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Bajwa, Rajbir Singh, and Navjot Brar. "A prospective randomized controlled study: early enteral nutrition following gastrointestinal surgery." International Surgery Journal 4, no. 10 (2017): 3249. http://dx.doi.org/10.18203/2349-2902.isj20174107.

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Background: The word anastomosis originates from the Greek word (ἀναστόμωσις) meaning communicating opening. Gut anastomosis is one of the frequently performed surgeries in both emergency and elective setup. Anastomosis following gut resections in emergency set up is mostly done due to traumatic rupture, benign or malignant perforation or obstruction and in certain other inflammatory conditions. Anastomosis is also done in some elective conditions like mostly due to malignancy of GI system. As conventional practice following gut anastomosis, patients are kept “NIL BY MOUTH” till bowel sounds return.Methods: It’s a prospective study, carried out over period of 18 months in Department of General Surgery, Sri Guru Ramdas Institute of Medical Sciences and Research, Vallah, Amritar. The objective of this study was to whether early enteral feeding within 48 hours of small gut anastomosis is tolerable to the patient. Whether early enteral feeding within 48 hours of small gut anastomosis is beneficial to the patient.Results: This prospectively conducted comparative study was carried out on 60 patients, meeting inclusion criteria, undergoing gastrointestinal anastomosis either elective or emergency, in the Department of General Surgery, SGRD Medical College, between Jan 2012 to June 2013. Random selection of patients into group A (30) and group B (30) was done after having fulfilled inclusion and exclusion criteria. The group A was fed via enteral route within 48 hrs of enteric anastomosis. The group B was fed via enteral route after 48-72 hours or appearance of full peristaltic sounds following enteric anastomosis. These patients were followed in post-operative period for their drain output, any nausea, vomiting, or significant abdominal distension, prolonged ileus, clinical leakage, infective complications, hospital stay.Conclusions: The following inferences can therefore be drawn from this study: Appearance of intestinal peristaltic sounds is earlier in early enterally fed group, Mean duration of post-operative hospital stay is lower in early enterally fed group, mean post-operative day 4 albumin level is higher in early enterally fed group. The rate of infective complications (UTI, RTI, wound complications) is equal in both the groups. The rate of clinical leakage, nausea/vomiting are equal in both the groups. The rate of re-exploration for anastomotic leakage is equal in both the groups.
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Rizzo, Giacomo Emanuele Maria, Chiara Coluccio, Edoardo Forti, et al. "Endoscopic Ultrasound-Guided Anastomoses of the Gastrointestinal Tract: A Multicentric Experience." Cancers 17, no. 5 (2025): 910. https://doi.org/10.3390/cancers17050910.

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This multicenter retrospective study included patients undergoing EUS-guided GI anastomoses from 2016 to 2023. Indications for EUS-guided anastomosis were GOO, ALS or patients with altered anatomy needing endoscopic interventions. The primary outcome was technical success, while secondary outcomes included clinical success, safety, lumen-apposing metal stent (LAMS) patency, and the need for reinterventions. A total of 216 patients (mean age 64.5 [±13.94] years; 49.1% males) were included. In total, 149 cases (69%) were GOO, 44 (20.4%) cases were bilioenteric anastomotic strictures or lithiasis in altered anatomy, 14 cases (6.5%) were ALS, and 9 patients (4.2%) were for ERCP in altered anatomy after EUS-GG. Overall, EUS-GE was performed in 181 patients (83.8%), EUS-JJ in 44 cases (20.4%), and EUS-GG in 10 (4.6%). Technical success was 94.91%, and clinical success was 93.66%. The adverse event (AE) rate was 11.1%. The reintervention rate was 7.69%. The median follow-up was 85 days. In conclusions, EUS-guided GI anastomoses are technically feasible and safe in both malignant and benign diseases.
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Juhi, Singh, Nagar Anju, Meena Dharmraj, Meena Meenesh, and Meena Radheyshyam. "Comparative Study between Single vs Double Layer Intestinal Anastomosis." International Journal of Toxicological and Pharmacological Research 13, no. 11 (2023): 149–53. https://doi.org/10.5281/zenodo.10998829.

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<strong>Background</strong><strong>:</strong>&nbsp;In gastrointestinal surgeries, intestinal anastomosis is a routine and important process. While double layer anastomosis was once thought to be secure, several surgeons now contend that single layer anastomosis with non-absorbable suture yields comparable outcomes.&nbsp;<strong>Methods:</strong>&nbsp;A single-centre retrospective cohort comparative study was conducted in the Department of General Surgery, Govt. Medical College and Hospital, Kota, Rajasthan, India during April 2022 to June, 2023. A total of 50 patients were taken, out of which 35 underwent double layer anastomosis and 15 patients had single layer anastomosis.&nbsp;<strong>Result:</strong>&nbsp;A total of fifty patients were enrolled; thirty-five underwent double layer anastomosis and fifteen underwent single layer anastomosis. Accordingly, the patients in each group were matched for diagnosis, sex, and age. Both the length of hospital stay and the mean time required for anastomosis were significantly shorter in Group-A. Compared to the double layer group, the single layer group experienced a faster postoperative return of bowel function. The double-layered group incurred a comparatively higher cost for the suture material used. However, there was no significant difference in the complication rates between the two groups.&nbsp;<strong>Conclusions</strong><strong>:</strong> There is not much difference in development of complications in both the methods. Both have same efficacy, mean time taken return of bowel movements. A single layer requires less operating time and is more economical.
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Rai, Arvind, and Sukantth R. J. "Study of clinical outcome of patients undergoing intestinal anastomoses with single layer extramucosal technique and double layer anastomoses." International Surgery Journal 8, no. 9 (2021): 2572. http://dx.doi.org/10.18203/2349-2902.isj20213181.

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Background: Intestinal anastomosis is one of the common surgeries for cases like bowel obstruction, incarcerated hernias, benign and malignant tumours of small and large bowel. The ideal intestinal anastomosis does not leak and allow normal function of the gastrointestinal tract. This study compared single layer versus double layer intestinal anastomosis in terms of duration, postoperative complications like anastomotic leak.Methods: A total of 100 patients admitted in Hamidia hospital, based on history and clinical examinations and radiological examinations, placed in two groups, group A (single layer anastomosis) and group B (double layer anastomosis) and were operated by a qualified surgical specialist. Data analysis of anastomotic time, anastomotic leak was done and statistical tests of significance were applied. A p value less than 0.05 is considered as significant.Results: In group A (single layer) the time required to perform in 30 (60%) patients is between 16-20 minutes. In double layer, maximum were done in between 26 to 30 minutes, 32 (64%). In our study of 100 patients, there were 6 anastomotic leaks, of which four of them were in group A (single layer) and 2 of them in group B (double layer).Conclusions: In our study, the duration required to perform a single layer intestinal anastomosis is significantly lesser when compared to double layer. There is no significant difference in anastomotic leak between two groups. Less time with no difference in complications, a move towards single layer anastomosis should be preferred.
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Liu, Qinjie, Pengfei Wang, Dong Lu, and Qingsong Tao. "Surgical management for the intra-abdominal infection secondary to perforation of digestive tract." World Journal of Surgical Infection 3, no. 1 (2024): 19–23. http://dx.doi.org/10.4103/wjsi.wjsi_4_24.

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Abdominal infection caused by digestive tract perforation is a common cause of emergency surgery. In most cases, resection of the diseased intestinal segment is required. After resection, whether to perform a one-stage anastomosis or a stomy is the key to perplexing clinicians. With the continuous improvement of surgical technology and the increasing demand of patients to improve their quality of life, one-stage resection and anastomosis have become the most ideal surgical method. However, due to the concern about postoperative anastomotic leakage, the clinical practice of postoperative stoma rate is still high. This article reviews the surgical treatment of abdominal infection caused by gastrointestinal perforation in recent years, and discusses various preventive measures for anastomotic leakage after primary anastomosis, so as to improve the rate of primary anastomosis, which is of great significance for improving the quality of life of patients and reducing the medical burden.
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Baruah, Alfred, Dhirendra Nath Choudhury, and Kamal Krishna Patowary. "A comparison of extra-mucosal single layer interrupted repair vs conventional double layer repair of intestinal anastomosis: a hospital-based study." International Journal of Research in Medical Sciences 12, no. 12 (2024): 4653–57. https://doi.org/10.18203/2320-6012.ijrms20243722.

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Background: Intestinal anastomosis is a critical surgical technique used to resect and reconnect segments of the gastrointestinal tract. Traditional double-layered techniques using both absorbable and non-absorbable sutures have been widely used. However, single-layer anastomosis is gaining interest due to its simplicity, cost-effectiveness, and reduced operating time. This study aims to compare the outcomes between extra-mucosal single-layer interrupted repair and conventional double-layer repair. Methods: A prospective, randomized controlled study was conducted over six months with 42 patients undergoing intestinal resection and anastomosis. Patients were randomized into two groups: single-layer anastomosis (Group A) and double-layer anastomosis (Group B). Both groups were monitored for key outcomes such as anastomotic leak, return of bowel function, surgical site infection, and hospital stay. Results: The single-layer technique showed a significantly shorter operative time (23.8±2.5 minutes) compared to the double-layer technique (33.1±2.6 minutes). There were no statistically significant differences in anastomotic leak rates, re-interventions, or surgical site infections between the two groups. The cost of materials was lower for single-layer anastomosis. Conclusions: Single-layer anastomosis offers a time-efficient, cost-effective alternative to double-layer anastomosis with comparable clinical outcomes. The findings support the broader adoption of the single-layer technique, particularly in resource-limited settings.
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LODHI, FAISAL BILAL, M. SHAFIQ, TARIQ FAROOQ, and Riaz Hussain. "ANASTOMOTIC LEAK AFTER SMALL GUT SURGERY." Professional Medical Journal 13, no. 01 (2006): 47–50. http://dx.doi.org/10.29309/tpmj/2006.13.01.5056.

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Background: Anastomotic leak after gastrointestinal surgery is animportant postoperative event that leads to significant morbidity and mortality. Postoperative leak rates are frequentlyused as an indicator of the quality of surgical care provided. Objective:(1).To define factors associated with leakageof small gut anastomosis. (2) To find technique of small gut anastomosis associated with lowest risk of anastomoticdehiscence. Study Design: Retrospective, Descriptive Duration: 02 Years (May 2003 to May 2005) Material andMethods: This study was conducted at Surgical Unit-II, Allied Hospital, Punjab Medical College, Faisalabad from Dec2003 to May 2005. A total number of 36 cases were included in this study comprising of both adult male and femalepatients developing anastomotic dehiscence following resection and end to end anastomosis of small gut. Results:Peritonitis was the risk factor identified in 69% of the patients. Hypovolemic shock both preoperatively and in theimmediate postoperative period was noted in 56% cases while 83% of the patients with anastomotic dehiscence hadhaemoglobin concentration less than 10g%. High concentration of blood urea was noted in 42% of the cases. It turnedto normal as soon as the hypovolemia was corrected in these cases. Small gut anastomosis done in emergency setting(75% cases) was associated with increased risk of anastomotic dehiscence as compared to the dehiscence noted in09 cases (25%) operated on elective list. Three different techniques were used for small gut anastomosis. The rate ofanastomotic leakage ranged from 19-45%. Conclusion: Peritonitis, hypovolaemia and low hemoglobin alone or incombination are associated with increased risk of small gut anastomotic leakage especially after emergency surgery.Single layered extramucosal interrupted anastomosis was associated with less risk of dehiscence than the full thicknessand continuous extramucosal anastomosis.
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Lo, S. F., A. W. C. Yip, and T. W. Chow. "SURGICAL AUDIT OF GASTROINTESTINAL ANASTOMOSIS." Annals of the College of Surgeons of Hong Kong 5, no. 3 (2001): A27. http://dx.doi.org/10.1046/j.1442-2034.2001.00106g.x.

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Lo, S. F., A. W. C. Yip, and T. W. Chow. "SURGICAL AUDIT OF GASTROINTESTINAL ANASTOMOSIS." Annals of the College of Surgeons Hong Kong 5, no. 3 (2001): A27. http://dx.doi.org/10.1046/j.1442-2034.2001.0106g.x.

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VORA, DR DEEPAK, DR RUSHIT DAVE, and DR NIKET SHAH. "Comparative Study of Gastrointestinal Anastomosis Stapler V/S Suture." Indian Journal of Applied Research 4, no. 6 (2011): 348–50. http://dx.doi.org/10.15373/2249555x/june2014/107.

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Parth, Patel, Shah Samir, Patel Jekee, and Parthasarthi Pranav. "A Prospective Comparative Study of 50 Cases of Intestinal Anastomosis by Stapler versus Hand Sewn Method." International Journal of Pharmaceutical and Clinical Research 15, no. 4 (2023): 854–58. https://doi.org/10.5281/zenodo.12675323.

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<strong>Background:&nbsp;</strong>Intestinal anastomosis in General Surgery is a very commonly performed procedure for various indications by various methods and for ancient times. Various evolvements occurred in the field of various aspects of intestinal anastomosis with recent advancement is the use of stapler as a device for GI anastomosis. Because of the use of staplers, technical failure is a rarity, anastomosis is more consistent and can be used at difficult locations.&nbsp;<strong>Method:&nbsp;</strong>A total of 50 cases which met the inclusion and exclusion criteria were included in this hospital based prospective comparative study. Than after taking informed and written consent of the patients, they have been operated by either hand-sewn or stapler methods of intestinal anastomosis randomly (25/25 cases). The subjects were allocated into two groups according to the type of anastomosis, hand sewn and stapler. Both the group of patients have been compared for various outcome measures: hospital stay, operation time, post-operative pain, post-op wound discharge, post-op anastomotic leakage, post-op resumption of day-to-day activity.&nbsp;<strong>Result:</strong>&nbsp;The patients, operated by stapler method of intestinal anastomosis have required less operation time and less hospital stay with significantly low rate of postoperative pain, wound discharge, anastomotic leakage and early resumption of routine daily activity.&nbsp;<strong>Conclusion:</strong>&nbsp;In our present study, we found that stapling technique can significantly reduce the time for anastomotic procedure, less tissue trauma due to less tissue handling, there is early restoration of gastrointestinal function, less post-operative complications including those of anastomotic site and reduced duration of hospital stay which helps ultimately in early return to routine work, importantly staplers can be used at places were hand sewn anastomosis is technically difficult. &nbsp; &nbsp; &nbsp;
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43

Tong, Dan, Jie Xiang, Peng Gao, Zhiming Zhu, and Zongshi Lu. "Modified Roux-en-Y gastric bypass surgery avoids complications in mice." PLOS One 20, no. 5 (2025): e0323706. https://doi.org/10.1371/journal.pone.0323706.

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Background Roux-en-Y gastric bypass(RYGB)surgery delivers an improvement in obesity and obesity-related risks. However, due to the limited operational space in the abdominal cavity of mice, the technical complexity of RYGB surgery and the postoperative complications hinder its mechanism research. The aim was to develop a device that makes it easier to anastomose the esophagus to the jejunum. Methods We have invented a simple gastrointestinal anastomosis auxiliary device consisting of a rigid front end and a flexible rear end. Thirty male C57BL6J mice were subjected to RYGB with an auxiliary device. Postoperative recovery and survival status of mice were evaluated using body weight, food intake, body fat, and glucose tolerance. Results Based on the RYGB surgical methodology reported in previous literature, the anastomosis device described in this article assists in end-to-end anastomosis of the esophagus and jejunum, which reduces surgical difficulty and time. CT scan results revealed that, following a short - term recovery period after mRYGB surgery, no leakage or stenosis was detected at the anastomotic site in the mice. Moreover, after postoperative recovery, there was no significant difference in food intake, weight and body fat distribution compared with Sham mice, but the glucose tolerance of mRYGB mice was significantly improved. Conclusions Our modified RYGB surgical method can effectively avoid the problems of anastomotic leakage and stenosis in mice and improve long-term quality of life.
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44

Vasaiya, Mehulkumar K., Samir M. Shah, Vikram B. Gohil, and Milankumar S. Vaghasia. "A prospective study of 50 cases of laparoscopic intestinal anastomosis by Endo GIA universal loading stapler (green/blue) versus Endo GIA articulating reload with tri staple technology (purple)." International Surgery Journal 7, no. 11 (2020): 3657. http://dx.doi.org/10.18203/2349-2902.isj20204667.

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Background: Intestinal anastomosis is a commonly performed procedure in surgery. Various evolvements have occurred in the field of intestinal anastomosis and recent advancement is the use of stapler in laparoscopic surgeries as a device for Gastrointestinal (GI) anastomosis. Few previous studies evaluating the clinical safety of the 2 laparoscopic linear stapling devices are available.Methods: A prospective comparative study of 50 cases which met the inclusion and exclusion criteria were included in this hospital-based study. They were randomly allocated to two groups, Group A which underwent laparoscopic intestinal anastomosis by Endo GIA tri-staple (purple) stapler and Group B which underwent Endo GIA universal loading unit (blue/green) stapler. Primary outcome was assessed in terms of intra-operative staple line bleeding, operative time and post-operative anastomotic leak.Results: Patients with laparoscopic intestinal anastomosis by Endo GIA tri-staple stapler (purple) have required less operation time as compared to Endo GIA universal loading unit. In Endo GIA universal loading unit (blue/green) 04% patients developed anastomotic leak and 40% patients had intra-operative staple line bleed while with Endo GIA tri-staple no postoperative anastomotic leak was found and 02% patients developed intra-operative staple line bleeding.Conclusions: The result of our study has shown that the Endo GIA reload tri- staple (purple) is superior in terms of having no anastomosis leak, negligent staple line bleeding and less operation time as compared with Endo GIA universal loading unit (blue/green). Thus, laparoscopic intestinal anastomosis by Endo GIA reload tri-staple stapler (purple) technology is more effective and overall more efficient.
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Rahman, S., MA Khair, F. Khanam, et al. "Double layer versus Single layer Gastro-intestinal anastomosis in gastric cancer surgery in Mymensingh Medical College Hospital." Community Based Medical Journal 2, no. 2 (2013): 30–34. http://dx.doi.org/10.3329/cbmj.v2i2.16695.

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Introduction: In gastric cancer surgery, gastrojejunostomy is one of the most important procedures. Anastomosis between different parts of the stomach and the intestine is a basic technical component in all gastrointestinal procedure. Backgrounds and aims: This study evaluated complications of gastrojejunostomy in gastric cancer surgery with two methods: single-layer and double-layer anastomosis. Materials and methods: This study was carried out in the department of surgery in Mymensingh Medical College Hospital from January 1, 2009 to December 31, 2012. 100 patients with carcinoma stomach who needed gastrojejunostomy were included in this study. These patients with average age of 43.22 years were divided in two groups (50 in each group); single-layer and double-layer anastomosis. In single-layer anastomosis gastrojejunostomy was performed in interrupted method with absorbable suture (2/0 vicryl). Double-layer anastomosis was carried out with continuous suture (2/0 silk, 2/0 catgut). Possible post-operative complications like anastomotic leakage, pelvic abscess, abdominal sepsis, anastomotic stenosis and wound infection were evaluated. Results: In the single-layer group, 4 patients (8%) developed anastomotic leakage, wound infection and only 2 patients (4%) developed abdominal sepsis, pelvic abscess and anastomotic bleeding. No patient developed anastomotic stricture. In double-layer group, 2 (4%) patients developed anastomotic leakage, only 1 (2%) patient had pelvic abscess, abdominal sepsis and anastomotic bleeding but wound infection in 2 (4%) patients. Conclusion: Gastrojejunostomy with single-layer hand-sewn suture technique is safe without serious complications in comparison to double-layer suture technique. More-over operation time is less and cost is less in single-layer method.DOI: http://dx.doi.org/10.3329/cbmj.v2i2.16695 Community Based Medical Journal 2013 July: Vol.02 No 02: 30-34
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46

Wang, Tim H. H., Timothy R. Angeli, Grant Beban, et al. "Slow-wave coupling across a gastroduodenal anastomosis as a mechanism for postsurgical gastric dysfunction: evidence for a “gastrointestinal aberrant pathway”." American Journal of Physiology-Gastrointestinal and Liver Physiology 317, no. 2 (2019): G141—G146. http://dx.doi.org/10.1152/ajpgi.00002.2019.

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Postsurgical gastric dysfunction is common, but the mechanisms are varied and poorly understood. The pylorus normally acts as an electrical barrier isolating gastric and intestinal slow waves. In this report, we present an aberrant electrical conduction pathway arising between the stomach and small intestine, following pyloric excision and surgical anastomosis, as a novel disease mechanism. A patient was referred with postsurgical gastroparesis following antrectomy, gastroduodenostomy, and vagotomy for peptic ulceration. Scintigraphy confirmed markedly abnormal 4-h gastric retention. Symptoms included nausea, vomiting, postprandial distress, and reflux. Intraoperative, high-resolution electrical mapping was performed across the anastomosis immediately before revision gastrectomy, and the resected anastomosis underwent immunohistochemistry for interstitial cells of Cajal. Mapping revealed continuous, stable abnormal retrograde slow-wave propagation through the anastomosis, with slow conduction occurring at the scar (4.0 ± 0.1 cycles/min; 2.5 ± 0.6 mm/s; 0.26 ± 0.15 mV). Stable abnormal retrograde propagation continued into the gastric corpus with tachygastria (3.9 ± 0.2 cycles/min; 1.6 ± 0.5 mm/s; 0.19 ± 0.12 mV). Histology confirmed ingrowth of atypical ICC through the scar, defining an aberrant pathway enabling transanastomotic electrical conduction. In conclusion, a “gastrointestinal aberrant pathway” is presented as a novel proposed cause of postsurgical gastric dysfunction. The importance of aberrant anastomotic conduction in acute and long-term surgical recovery warrants further investigation. NEW &amp; NOTEWORTHY High-resolution gastric electrical mapping was performed during revisional surgery in a patient with severe gastric dysfunction following antrectomy and gastroduodenostomy. The results revealed continuous propagation of slow waves from the duodenum to the stomach, through the old anastomotic scar, and resulting in retrograde-propagating tachygastria. Histology showed atypical interstitial cells of Cajal growth through the anastomotic scar. Based on these results, we propose a “gastrointestinal aberrant pathway” as a mechanism for postsurgical gastric dysfunction.
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47

TAKIGUCHI, Nobuhiro, Norio SAITOH, Keiji KODA, et al. "Clinical assessment of gastrointestinal anastomosis by using biofragmentable anastomosis ring." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 61, no. 10 (2000): 2583–87. http://dx.doi.org/10.3919/jjsa.61.2583.

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48

Berlin, P., A. Fischer, J. Reiner, C. Schafmeyer, G. Lamprecht, and M. Witte. "P129 Anastomotic healing is functionally not impaired after ileocecal resection in a mouse model of Crohn's-like ileitis." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i423. http://dx.doi.org/10.1093/ecco-jcc/jjad212.0259.

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Abstract Background Anastomotic leakage (AL) is a serious complication after gastrointestinal surgery that seems to occur more frequently in patients with CD than in non-IBD patients. Nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) is a risk gene for CD. We have recently demonstrated that Nod2-deficent mice have impaired anastomotic healing after ileocecal resection (ICR) even in the absence of a Crohn's phenotype. It is not yet understood how CD itself affects anastomotic healing. SAMP1/YitFc mice spontaneously develop Crohn's-like ileitis and show a defect in the NOD2 receptor. With this study we aimed to investigate whether anastomotic healing is altered after ICR in experimental ileitis. Methods SAMP1/YitFc mice (n=17) with histologically manifest ileitis and parental controls (AKR, n=12) were subjected to ICR. Intestinal continuity was established by end-to-end ileocolic anastomosis. On day 5, the strength of the anastomosis was assessed by bursting pressure (BP) measurement. Anastomotic healing was evaluated macroscopically using the anastomotic healing score (AHS). Hydroxyproline content and collagenase activity in the anastomosis were determined. The inflammatory status was determined by mRNA expression of inflammatory cytokines in mesenteric lymph nodes (MLN) and spleen tissue. Results 25% of the AKR mice and 29% of the SAMP1/YitFc mice developed perioperative complications. Leakage rate was not higher in mice with ileitis. Functionally, anastomoses were not impaired in SAMP1/YitFc mice (BP SAMP1 93 mmHg vs. AKR 123 mmHg) and AHS did not differ between the groups. However, mice with ileitis were more prone to microscopic abscess formation. Collagenase activity and hydroxyproline content in the anastomotic tissue did also not differ significantly. Preoperatively, mice with ileitis expressed increased IL4 and INF-γ mRNA levels in the MLN compared to AKR controls. After ICR, the local expression of IL4, TNF-α, lysozyme 1 and IL2 was significantly decreased in SAMP1/YitFc mice (p&amp;lt;0.05 SAMP1 d0 vs. d5, MLN). Resection induced significantly increased expression of IL4, lysozyme 1 and IL2 in the spleen of AKR mice, but not in SAMP1/YitFc mice (p&amp;lt;0.05 AKR ICR vs. SAMP1 ICR d5). Conclusion The SAMP1/YitFc mouse is a suitable model to study mechanisms of anastomotic healing under the influence of experimental chronic ileitis. Ileitis alone was not a risk factor for impaired healing. Ongoing studies address the local effects of therapeutic immunomodulation on the healing process of the anastomoses.
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49

Park, Adrian E., Gina L. Adrales, Roderick Mckinlay, and Charles Knapp. "A Novel Intestinal Anastomotic Device in a Porcine Model." American Surgeon 70, no. 9 (2004): 767–74. http://dx.doi.org/10.1177/000313480407000904.

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The purpose of this study was to evaluate a novel, intraluminally deployed anastomotic device (AD). A survival study was conducted in 18 farm pigs. One early subject was excluded and replaced due to premature expiration. Six animals were placed in 1 of 3 cohorts, with euthanasia and AD explantation planned at 2, 4, and 6 weeks. A distal small intestinal side-side [functional end-end] anastomosis using the AD was performed via midline laparotomy. Fluoroscopy with double-contrast dilute barium and burst pressure measurements were performed in 4 animals in each group. Two animals in each cohort underwent fluoroscopy without contrast and resection for histology. Mucosal healing, inflammation, anastomotic alignment of the muscularis propria, and fibrosis were graded on a 4-point scale. All animals survived to the date of planned euthanasia except the excluded subject, who expired from causes unrelated to the device. Normal weight gain was seen in all. Sixteen of 18 devices sloughed prior to extraction without evidence of injury or obstruction during the survival period or at necropsy. Filling pressures of &gt;200 mm Hg were reached; no leakage was seen. Mucosal healing and continuity were graded good to excellent at 2 weeks and excellent at 4 and 6 weeks. Inflammation improved with time, with moderate change at 2 weeks and mild at 6 weeks. Anastomotic fibrosis was mild at 2 weeks, mild to minimal at 4 weeks, and minimal at 6 weeks. The anastomotic alignment was 100 per cent except in 1 animal at 2 weeks with &gt;50 per cent but &lt;100 per cent alignment. The AD resulted in a stable, functional anastomosis without narrowing. All tested anastomoses withstood supraphysiologic insufflation pressures without evidence of disruption. The applicability of this novel device will be explored for use in other gastrointestinal and biliary anastomoses using minimally invasive deployment techniques.
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Sayeed, Dr Abu, Md Aminul Islam, Dr Md Abdul Kuddus Mondal, Dr Monishankor Roy, Dr Sarder Belal Hossain, and Dr Md Belal Uddin Akanda. "Single Versus Double Layer Intestinal Anastomosis: A Comparison of Features and Treatment Outcomes." SAS Journal of Surgery 11, no. 02 (2025): 123–28. https://doi.org/10.36347/sasjs.2025.v11i02.003.

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Background: Intestinal anastomosis is a critical surgical procedure for restoring gastrointestinal continuity after resection. The choice between single-layer and double-layer anastomosis techniques remains a subject of debate, with implications for operative time, complication rates, and long-term outcomes. This study aimed to compare the features and treatment outcomes of single-layer versus double-layer intestinal anastomosis. Methods: This comparative study, conducted at Shaheed Ziaur Rahman Medical College Hospital in 2011, included 92 patients undergoing intestinal anastomosis. Group I (45 patients) had single-layer anastomosis, while Group II (47 patients) underwent double-layer procedures. Data were analyzed using SPSS 23.0, with participants selected via consecutive sampling. Results: Postoperative bowel function returned faster in the single-layer group (76.27 hours) compared to the double-layer group (85.91 hours). First oral intake began earlier in the single-layer group. Wound infection rates were 6.66% in Group I and 12.58% in Group II. Anastomotic leakage occurred in 4.44% of Group I and 10.56% of Group II patients. Mortality was 0% in Group I and 2.12% in Group II. Hospital stays averaged 9.42 days for Group I and 10.8 days for Group II. Conclusion: The single-layer anastomosis method offers notable advantages over the double-layer conventional technique. Patients undergoing single-layer anastomosis experience a quicker postoperative return of bowel function and an earlier initiation of oral feeding. Additionally, this approach is associated with a lower incidence of anastomotic failure and septic complications. Consequently, single-layer anastomosis is both a safe and cost-effective option for surgical treatment.
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