Log in

Relevant bibliographies by topics / GBS met / Journal articles

To see the other types of publications on this topic, follow the link: GBS met.

Journal articles on the topic 'GBS met'

Author: Grafiati

Published: 24 April 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'GBS met.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

COPPENS H, VERGUTS L, VERVLIET J, and KERSEMANS L. "Intrapartale spoeling met chloorhexidine als preventie van neonatale kolonisatie met groep-B-streptokokken (GBS)." Tijdschrift voor Geneeskunde 56, no. 21 (January 1, 2000): 1558–62. http://dx.doi.org/10.2143/tvg.56.21.5000889.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Murphy, Robert E., Jane C. Ibekwe, Stella I. Ibekwe, and Jerrie S. Refuerzo. "A Structural, Cognitive, and Behavioral Model for Error Analysis of Group B Streptococcus Prophylaxis in Pregnancy." American Journal of Perinatology Reports 12, no. 01 (January 2022): e17-e26. http://dx.doi.org/10.1055/s-0041-1742235.

Full text

Abstract:

AbstractThe objective of this study was to develop a structural-cognitive-behavioral model for error analysis of group B streptococcus (GBS) prophylaxis failure, classify delivery cases into this model, and examine compliance with treatment guidelines. A retrospective, cohort study was conducted of women with liveborn pregnancies greater than 24 weeks in April 2018 at a single hospital. We created a structural-cognitive-behavioral model of five assessments for adherence to GBS prophylaxis guidelines and then classified these into four distinct error stages. A descriptive analysis was performed to determine if the pregnancy had a perfect process, a GBS prophylaxis failure, or a fortuitous outcome. There were 313 women who met the study criteria. The rate of GBS positive was 12.8%, negative 37.4%, and unknown 49.8%. The most common errors were cognitive perception errors related to incorrectly documenting GBS status, 57.7% (N = 79). Of these errors, 15.2% (N = 12) led to GBS prophylaxis failure. Perfect outcomes occurred in 62.7% (N = 196) women, GBS prophylaxis failure occurred in 13.7% (N = 43), and fortuitous outcomes occurred in 23.6% (N = 74). In our study, we were able to identify structural, cognitive, and behavioral errors that contribute to GBS prophylaxis failures. In other cases, these errors may contribute to fortuitous outcomes.

APA, Harvard, Vancouver, ISO, and other styles

3

Bourque, Pierre R., John Brooks, Christopher R. McCudden, Jodi Warman-Chardon, and Ari Breiner. "Age matters." Neurology - Neuroimmunology Neuroinflammation 6, no. 4 (May 21, 2019): e576. http://dx.doi.org/10.1212/nxi.0000000000000576.

Full text

Abstract:

ObjectiveWe conducted a retrospective review of patients with a diagnosis of Guillain-Barré syndrome (GBS) to assess the diagnostic impact of applying age-adjusted upper limits for CSF total protein (CSF-TP) supported by a systematic literature review.MethodsCases coded as GBS or inflammatory neuropathy for the period 2001–2016 at The Ottawa Hospital were reviewed. Cases were included if they met the Brighton criteria for GBS with a diagnostic certainty level 1 or 2 and had contemporaneous CSF-TP data. We excluded cases with CSF pleocytosis >50 and cases with Miller-Fisher syndrome. Age-adjusted reference limits were compared with conventional 0.45 and 0.6 g/L upper limits.ResultsOne hundred thirty-eight cases met the study criteria, with a mean age of 47 years. The mean interval from symptom onset to lumbar puncture was 7.9 days, and mean CSF-TP was 1.23 g/L. There was a strong correlation between rising CSF-TP and time to lumbar puncture. Age-adjusted CSF-TP had a significantly lower sensitivity of only 45% in the first week (32% in the first 3 days) compared with 70% in the first week for the 0.45 g/L limit. All upper limits gained high sensitivity after the first week.ConclusionsThe low sensitivity of CSF-TP for the diagnosis of GBS is exacerbated by age-adjusted upper limits. The main role of lumbar puncture in GBS in the first week may be to help exclude other inflammatory or neoplastic etiologies of acute neuropathy. After the first week, the magnitude of the CSF-TP rise reduces the effect of different upper reference limits.

APA, Harvard, Vancouver, ISO, and other styles

4

Kleweis, Shelby M., Alison G. Cahill, Anthony O. Odibo, and Methodius G. Tuuli. "Maternal Obesity and Rectovaginal Group B Streptococcus Colonization at Term." Infectious Diseases in Obstetrics and Gynecology 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/586767.

Full text

Abstract:

Objective. To test the hypothesis that maternal obesity is an independent risk factor for rectovaginal group B streptococcus (GBS) colonization at term.Study Design. Retrospective cohort study of consecutive women with singleton term pregnancies admitted in labor at Barnes-Jewish Hospital (2004–2008). Maternal BMI ≥ 30 Kg/m2(obese) or <30 Kg/m2(nonobese) defined the two comparison groups. The outcome of interest was GBS colonization from a positive culture. Baseline characteristics were compared using Student’st-test and Chi-squared or Fisher’s exact test. The association between obesity and GBS colonization was assessed using univariable and multivariable analyses.Results. Of the 10,564 women eligible, 7,711 met inclusion criteria. The prevalence of GBS colonization in the entire cohort was relatively high (25.8%). Obese gravidas were significantly more likely to be colonized by GBS when compared with nonobese gravidas (28.4% versus 22.2%,P<0.001). Obese gravidas were still 35% more likely than nonobese women to test positive for GBS after adjusting for race, parity, smoking, and diabetes (adjusted OR 1.35 [95% CI 1.21–1.50]).Conclusion. Maternal obesity is a significant risk factor for GBS colonization at term. Further research is needed to evaluate the impact of this finding on risk-based management strategies.

APA, Harvard, Vancouver, ISO, and other styles

5

Buckler, Brad, Jason Bell, Ralph Sams, William Cagle, Sue Anne Bell, Carla Allen, Don Sutherland, and Jatinder Bhatia. "Unnecessary Workup of Asymptomatic Neonates in the Era of Group B Streptococcus Prophylaxis." Infectious Diseases in Obstetrics and Gynecology 2010 (2010): 1–3. http://dx.doi.org/10.1155/2010/369654.

Full text

Abstract:

Asymptomatic term neonates born to mothers who are Group B Streptococcus (GBS) unknown or GBS positive but “inadequately” treated prior to delivery do not require invasive laboratory evaluation. We conducted a retrospective cohort study of mother/baby dyads born from January 1, 2005 until September 30, 2007 at the Medical College of Georgia. Their current protocol is to obtain a Complete Blood Count with Differential (CBC with D), Blood Culture (BC), and C-reactive protein (CRP) after birth. Mother/baby dyads () that met inclusion criteria were reviewed. Of these 242 babies 25 (10%) were started on antibiotics after the initial lab values were known. None of the blood cultures were positive and the CRP's were normal. The 2002 GBS guidelines call for laboratory evaluation of “at-risk” neonates, but the workup of these babies is not only costly, it does not provide any advantage over old fashioned clinical observation for the evaluation and treatment of early onset GBS sepsis.

APA, Harvard, Vancouver, ISO, and other styles

6

Dakik, Hassan K., F. Douglas Srygley, Shih-Ting Chiu, Shein-Chung Chow, and Deborah A. Fisher. "Clinical Performance of Prediction Rules and Nasogastric Lavage for the Evaluation of Upper Gastrointestinal Bleeding: A Retrospective Observational Study." Gastroenterology Research and Practice 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/3171697.

Full text

Abstract:

Introduction. The majority of patients with acute upper gastrointestinal bleeding (UGIB) are admitted for urgent endoscopy as it can be difficult to determine who can be safely managed as an outpatient. Our objective was to compare four clinical prediction scoring systems: Glasgow Blatchford Score (GBS) and Clinical Rockall, Adamopoulos, and Tammaro scores in a sample of patients presenting to the emergency department of a large US academic center. Methods. We performed a retrospective cohort study of patients during 2008–2010. Our outcome was significant UGIB defined as high-risk stigmata on endoscopy, or receipt of blood transfusion or surgery, or death. Results. A total of 393 patients met inclusion criteria. The GBS was the most sensitive for detecting significant UGIB at 98.30% and had the highest negative predictive value (90.00%). Adding nasogastric lavage data to the GBS increased the sensitivity to 99.57%. Conclusions. Of all four scoring systems compared, the GBS demonstrated the highest sensitivity and negative predictive value for identifying a patient with a significant UGIB. Therefore, patients with a 0 score can be safely managed as an outpatient. Our results also suggest that performing a nasogastric lavage adds little to the diagnosis UGIB.

APA, Harvard, Vancouver, ISO, and other styles

7

Mithal, Leena B., Nirali Shah, Anna Romanova, and Emily S. Miller. "Antenatal Screening for Group B Streptococcus in the Setting of Preterm Premature Rupture of Membranes: Empiric versus Culture-based Prophylaxis." American Journal of Perinatology Reports 10, no. 01 (January 2020): e26-e31. http://dx.doi.org/10.1055/s-0039-3401807.

Full text

Abstract:

Abstract Objective Imperfect culture sensitivity and increase of early onset neonatal sepsis (EONS) risk in preterm neonates raise concern that culture-based intrapartum antibiotic prophylaxis (IAP) may be insufficient after preterm premature rupture of membranes (PPROM). Our objective was to compare rates of EONS after empiric versus culture-based IAP in PPROM. Study Design This retrospective cohort study included women with a singleton gestation and PPROM between 23 and 33 weeks. Outcomes after culture-based IAP were compared with empiric IAP. The primary outcome was EONS. Secondary outcomes included group B streptococcus (GBS) bacteremia, bacteremia, and neonatal GBS infection. Bivariable and multivariable logistic analyses were performed. Results Of the 270 women who met inclusion criteria, 136 (50%) had culture-based IAP of whom 36 (26.5%) were GBS positive. There was no significant difference in bacteremia (2.2 vs. 4.5%, p = 0.30), GBS infection (0.8 vs. 0.7%, p = 1.00), or EONS (11.8 vs. 12.7%, p = 0.82) in infants of women with culture-based IAP compared with empiric IAP. Multivariable analysis confirmed a lack of advantage to empiric versus culture-based IAP in EONS risk (adjusted odds ratio [aOR] = 0.82, 95% confidence interval [CI]: 0.44–1.93). Conclusion In pregnancies complicated by PPROM, infants of women who received culture-based IAP had no significant difference in EONS or GBS infection compared with infants of women with empiric IAP.

APA, Harvard, Vancouver, ISO, and other styles

8

Mongilardi, Nicole, Robin Jump, Federico Perez, Taissa Bej, Janet M. Briggs, Richard Banks, Brigid Wilson, and Sunah Song. "Minimal Mortality Among Veterans with Urine Cultures Positive for Group B Streptococcus." Antimicrobial Stewardship & Healthcare Epidemiology 1, S1 (July 2021): s36—s37. http://dx.doi.org/10.1017/ash.2021.67.

Full text

Abstract:

Background: Group B Streptococcus (GBS) can cause life-threating invasive infections, yet GBS is also a normal component of the intestinal and genitourinary tract. Although it is regarded as a potential urinary pathogen, the morbidity and mortality associated with recovery of GBS from urine cultures of nonpregnant adults is not well understood. We evaluated characteristics and mortality among nonpregnant adults with urine cultures that grew GBS. Methods: Using administrative data from the Veterans’ Healthcare Administration (VHA), we conducted a retrospective cohort study of VA healthcare system users from January 1, 2008, through December 31, 2017, with monomicrobial urine cultures growing ≥100,000 colony-forming units of GBS. Urinary tract infection (UTI) cases were defined as urinalysis positive for leukocyte esterase and pyuria (≥10 white blood cells), an International Classification of Diseases (ICD) code for UTI, and an antibiotic prescription. Cases with colonization were defined as negative for leukocyte esterase and pyuria, no ICD code for UTI, and no antibiotic prescription. Cases not meeting either definition were deemed unclassifiable. We compared demographics, comorbidities, and all-cause mortality among these 3 groups. Results: Over the 10-year study period, 26,848 veterans had 30,740 urine cultures positive for GBS. Applying the definitions above, there were 2,807 cases of infection, 8,789 cases of colonization, and 15,252 cases that were unclassifiable. Patients with a GBS UTI were slightly older compared to those who were colonized, with a higher Charlson comorbidity index and greater burden of chronic renal disease (Table 1). Individuals with infection versus colonization had 30-day mortality rates of 1% and 0%, respectively, and 1-year mortality rates of 9% and 4%, respectively (Figure 1). Conclusions: The association of a greater burden of illness among veterans who met our definition of UTI compared to colonization might be more reflective of providers’ responses to patients with chronic medical conditions rather than a difference in GBS as a cause of UTI. Overall, the prospect of a urine culture that grows GBS does not appear to be associated with adverse long-term outcomes.Funding: NoDisclosures: None

APA, Harvard, Vancouver, ISO, and other styles

9

Rajack, F., A. Afsari, A. M. Ramadan, and T. J. Naab. "An Emerging Infection: Streptococcal Toxic Shock-Like Syndrome Caused By Group B Streptococcus (GBS), Streptococcus Agalactiae." American Journal of Clinical Pathology 154, Supplement_1 (October 2020): S140. http://dx.doi.org/10.1093/ajcp/aqaa161.306.

Full text

Abstract:

Abstract Introduction/Objective Streptococcus agalactiae, Group B Streptococcus (GBS), is a major cause of neonatal sepsis and infections in pregnant women. However, incidence of invasive GBS infections has more than doubled in the last two decades with highest risk in adults 65 years or older. Other risk factors are diabetes, malignancy, and immunocompromised state. Bacteremia and skin soft tissue infections are the most common invasive infections in nonpregnant adults. Rarely GBS infection has a fulminating pyrogenic exotoxin-mediated course characterized by acute onset, multiorgan failure, shock, and sometimes death, referred to as toxic shock-like syndrome. Methods A 77-year-old hypertensive female with uncontrolled type 2 diabetes mellitus and a history of bilateral foot ulcers presented to the hospital in probable septic shock. Clinical diagnosis of necrotizing fasciitis was made and she underwent bilateral lower limb amputations. Results Grossly soft tissue appeared gray. Microscopically fascia was necrotic without neutrophils present and Gram stain revealed sheets of Gram positive cocci. These findings reflected histopathologic Stage III necrotizing fasciitis, which is associated with 47% mortality. Autopsy showed a similar histology of Stage III necrotizing fasciitis involving the surgical stump. Erythema and desquamation of the upper limbs bilaterally and multi-organ failure met the clinical picture of Streptococcal Toxic Shock Syndrome (STSS) and fulfilled the criteria for TSS due to Group A Streptococcus (GAS), defined by The Working Group on Severe Streptococcal Infections. Conclusion Group B Streptococcal Toxic Shock-Like Syndrome may have a similar outcome to STSS caused by GAS and other pathogens and, in limited studies, mortality has been 30% or greater.

APA, Harvard, Vancouver, ISO, and other styles

10

Ngonzi, Joseph, Lisa M. Bebell, Joel Bazira, Yarine Fajardo, Dan Nyehangane, Yap Boum, Deborah Nanjebe, et al. "Risk Factors for Vaginal Colonization and Relationship between Bacterial Vaginal Colonization and In-Hospital Outcomes in Women with Obstructed Labor in a Ugandan Regional Referral Hospital." International Journal of Microbiology 2018 (September 20, 2018): 1–7. http://dx.doi.org/10.1155/2018/6579139.

Full text

Abstract:

Introduction. The proportion of women with severe maternal morbidity from obstructed labor is between 2 and 12% in resource-limited settings. Maternal vaginal colonization with group B streptococcus (GBS), Escherichia coli, and Enterococcus spp. is associated with maternal and neonatal morbidity. It is unknown if vaginal colonization with these organisms in obstructed labor women is associated with poor outcomes. Objectives. To determine whether vaginal colonization with GBS, E. coli, or Enterococcus is associated with increased morbidity among women with obstructed labor and to determine the risk factors for colonization and antibiotic susceptibility patterns. Methods. We screened all women presenting in labor to Uganda’s Mbarara Regional Referral Hospital maternity ward from April to October 2015 for obstructed labor. Those meeting criteria had vaginal swabs collected prior to Cesarean delivery and surgical antibiotic prophylaxis. Swabs were inoculated onto sterile media for routine bacterial culture and antimicrobial susceptibility testing. Results. Overall, 2,168 women were screened and 276 (13%) women met criteria for obstructed labor. Vaginal swabs were collected from 272 women (99%), and 170 (64%) were colonized with a potential pathogen: 49% with E. coli, 5% with GBS, and 8% with Enterococcus. There was no difference in maternal and fetal clinical outcomes between those colonized and not colonized. The number of hours in labor was a significant independent risk factor for vaginal colonization (aOR 1.02, 95% CI 1.00–1.03, P=0.04). Overall, 38% of GBS was resistant to penicillin; 61% of E. coli was resistant to ampicillin, 4% to gentamicin, and 5% to ceftriaxone and cefepime. All enterococci were ampicillin and vancomycin susceptible. Conclusion. There was no difference in maternal or neonatal morbidity between women with vaginal colonization with E. coli, GBS, and Enterococcus and those who were not colonized. Duration of labor was associated with increased risk of vaginal colonization in women with obstructed labor.

APA, Harvard, Vancouver, ISO, and other styles

11

Cong, P., V. Pricolo, P. Biancani, and J. Behar. "Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle." American Journal of Physiology-Gastrointestinal and Liver Physiology 299, no. 3 (September 2010): G742—G750. http://dx.doi.org/10.1152/ajpgi.00064.2010.

Full text

Abstract:

The contraction of gallbladders (GBs) with cholesterol stones is impaired due to high cholesterol concentrations in caveolae compared with GBs with pigment stones. The reduced contraction is caused by a lower cholecystokinin (CCK)-8 binding to CCK-1 receptors (CCK-1R) due to caveolar sequestration of receptors. We aimed to examine the mechanism of cholesterol-induced sequestration of receptors. Muscle cells from human and guinea pig GBs were studied. Antibodies were used to examine CCK-1R, antigens of early and recycling endosomes, and total (CAV-3) and phosphorylated caveolar-3 protein (pCAV-3) by Western blots. Contraction was measured in muscle cells transfected with CAV3 mRNA or clathrin heavy-chain small-interfering RNA (siRNA). CCK-1R returned back to the bulk plasma membrane (PM) 30 min after CCK-8 recycled by endosomes, peaking at 5 min in early endosomes and at 20 min in recycling endosomes. Pretreatment with cholesterol-rich liposomes inhibited the transfer of CCK-1R and of CAV-3 in the endosomes by blocking CAV-3 phosphorylation. 4-Amino-5-(4-chloro-phenyl)-7-( t-butyl)pyrazolo[3,4- d]pyrimidine (inhibitor of tyrosine kinase) reproduced these effects by blocking pCAV-3 formation, increasing CAV-3 and CCK-1R sequestration in the caveolae and impairing CCK-8-induced contraction. CAV-3 siRNA reduced CAV-3 protein expression, decreased CCK-8-induced contraction, and accumulated CCK-1R in the caveolae. Abnormal concentrations of caveolar cholesterol had no effect on met-enkephalin that stimulates a δ-opioid receptor that internalizes through clathrin. We found that impaired muscle contraction in GBs with cholesterol stones is due to high caveolar levels of cholesterol that inhibits pCAV-3 generation. Caveolar cholesterol increases the caveolar sequestration of CAV-3 and CCK-1R caused by their reduced recycling to the PM.

APA, Harvard, Vancouver, ISO, and other styles

12

Artemiadis, Artemios K. "Neuropathic Pain in Acute and Subacute Neuropathies: A Systematic Review." January 2018 1, no. 21;1 (February 15, 2018): 111–20. http://dx.doi.org/10.36076/ppj.2018.2.111.

Full text

Abstract:

Background: Neuropathic pain (NP) is a common symptom caused by lesions or diseases of the somatosensory nervous system. Acute/subacute peripheral neuropathies (APN) are rare, however can be particularly painful. Objectives: The aim of this systematic review was to estimate the incidence of NP in APN and overview the various etiologies of such neuropathies. Study Design: Systematic review. Setting: Medline search. Methods: We hand-searched Medline for observational studies published between 1995 and 2017. Results: Our search strategy identified 1,400 papers. Of these, 70 met our inclusion criteria and were included in this review. Out of a total of 2,341 patients, 1,139 patients were diagnosed with NP (pooled incidence of NP 48.7%). In Guillain-Barré syndrome (GBS), the commonest cause of APN, the pooled estimate of NP was 34.8%. Other causes of painful APN include immunemediated, vasculitic, metabolic, nutritional, toxic, paraneoplastic, and infectious. Limitations: An important limitation was that GBS accounted for the majority of patients with APN, as such the calculated incidence reflected mainly this disease entity. Another important limitation was that very few studies targeted primarily NP. Thus, it is highly likely that observational studies reporting NP were missed. Finally there could always be a publication bias due to underreporting and gray literature. Conclusions: NP is a cardinal manifestation of APN. The use of validated diagnostic tools and accepted diagnostic criteria of NP is recommended for both clinical and research purposes. Key words: Neuropathic, pain, acute, subacute, neuropathy, polyneuropathy, frequency, incidence

APA, Harvard, Vancouver, ISO, and other styles

13

Del Carpio-Orantes, Luis, Jesús Salvador Sánchez-Díaz, Karla Gabriela Peniche Moguel, Sergio García-Méndez, Miguel Arnulfo Perfecto-Arroyo, Ishar Solis-Sánchez, Maria del Pilar Mata-Miranda, et al. "1680. Guillain Barré Syndrome in Arbovirus Outbreak in Veracruz, Mexico: The Follow-up to 3 Years of the Pandemic." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S615. http://dx.doi.org/10.1093/ofid/ofz360.1544.

Full text

Abstract:

Abstract Background From the arrival of Zika to America in 2015, and the increase in cases of Guillain sweeten in South America apparently associated with acute viral infection, Mexico had its first contact in 2016, with an increase in the incidence of cases of the syndrome, initiating a protocol study to look for the causal association of the Zika virus syndrome Methods We conducted a descriptive, prospective, and longitudinal study in Veracruz, Mexico, where follow-up of cases of Guillain Barre Syndrome (GBS) occurred during 2016 to 2018. The central point of the study is to look for the etiological association of GBS with the presence of acute zika infection. Secondarily, other know neutropic agents, both viral and bacterial were searched. The diagnosis techniques used were PCR-RT (blood and urine) and IgM/IgG for Zika; serum PCR-RT and IgM/IgG for Dengue and Chikungunya; IgM/IgG for TORCH; PCR-RT in CSF for Herpes and Enterovirus; serological panel of Hepatitis B and C; PCR-RT in rectal swab for Campylobacter. Results A cohort of 39 patients has been formed over 3 years of study. 38 patients met the operational definition of a suspected case of Zika, of which only 2 cases were identified by PCR-RT in urine; During the search protocol for infectious agents, others were identified such as: Dengue, Chikungunya, Enterovirus, Herpes and Hepatitis B; however, the identification of Campylobacter was even more remarkable, also highlighting that only four patients had diarrhea. Regarding the treatment, 37 patients received IVIG, 1 patient received plasmapheresis and 1 patient received both. The prognosis was good in 34 patients (basal Hugues from 4–5 to 2), 5 had poor functional prognosis and died. Conclusion The incidence of Zika as a cause of GBS is relatively low (5%), so the etiological association could not be demonstrated; other neurotropic viral agents were identified, however the presence of Campylobacter cases was more notable (asymptomatic campylobacteriosis). Disclosures All authors: No reported disclosures.

APA, Harvard, Vancouver, ISO, and other styles

14

Halani, Sheliza, Panashe E. Tombindo, Ryan O’Reilly, Rafael N. Miranda, Laura K. Erdman, Clare Whitehead, Joanna M. Bielecki, et al. "Clinical manifestations and health outcomes associated with Zika virus infections in adults: A systematic review." PLOS Neglected Tropical Diseases 15, no. 7 (July 12, 2021): e0009516. http://dx.doi.org/10.1371/journal.pntd.0009516.

Full text

Abstract:

Background Zika virus (ZIKV) has generated global interest in the last five years mostly due to its resurgence in the Americas between 2015 and 2016. It was previously thought to be a self-limiting infection causing febrile illness in less than one quarter of those infected. However, a rise in birth defects amongst children born to infected pregnant women, as well as increases in neurological manifestations in adults has been demonstrated. We systemically reviewed the literature to understand clinical manifestations and health outcomes in adults globally. Methods This review was registered prospectively with PROPSERO (CRD 42018096558). We systematically searched for studies in six databases from inception to the end of September 2020. There were no language restrictions. Critical appraisal was completed using the Joanna Briggs Institute Critical Appraisal Tools. Findings We identified 73 studies globally that reported clinical outcomes in ZIKV-infected adults, of which 55 studies were from the Americas. For further analysis, we considered studies that met 70% of critical appraisal criteria and described subjects with confirmed ZIKV. The most common symptoms included: exanthema (5,456/6,129; 89%), arthralgia (3,809/6,093; 63%), fever (3,787/6,124; 62%), conjunctivitis (2,738/3,283; 45%), myalgia (2,498/5,192; 48%), headache (2,165/4,722; 46%), and diarrhea (337/2,622; 13%). 36/14,335 (0.3%) of infected cases developed neurologic sequelae, of which 75% were Guillain-Barré Syndrome (GBS). Several subjects reported recovery from peak of neurological complications, though some endured chronic disability. Mortality was rare (0.1%) and hospitalization (11%) was often associated with co-morbidities or GBS. Conclusions The ZIKV literature in adults was predominantly from the Americas. The most common systemic symptoms were exanthema, fever, arthralgia, and conjunctivitis; GBS was the most prevalent neurological complication. Future ZIKV studies are warranted with standardization of testing and case definitions, consistent co-infection testing, reporting of laboratory abnormalities, separation of adult and pediatric outcomes, and assessing for causation between ZIKV and neurological sequelae.

APA, Harvard, Vancouver, ISO, and other styles

15

Das, Arabinda, Ron Ron Cheng, Megan L. T. Hilbert, Yaenette N. Dixon-Moh, Michele Decandio, Alex Vandergrift William, Naren L. Banik, et al. "Synergistic Effects of Crizotinib and Temozolomide in Experimental FIG-ROS1 Fusion-Positive Glioblastoma." Cancer Growth and Metastasis 8 (January 2015): CGM.S32801. http://dx.doi.org/10.4137/cgm.s32801.

Full text

Abstract:

Glioblastoma (GB) is the most common malignant brain tumor. Drug resistance frequently develops in these tumors during chemotherapy. Therefore, predicting drug response in these patients remains a major challenge in the clinic. Thus, to improve the clinical outcome, more effective and tolerable combination treatment strategies are needed. Robust experimental evidence has shown that the main reason for failure of treatments is signal redundancy due to coactivation of several functionally linked receptor tyrosine kinases (RTKs), including anaplastic lymphoma kinase (ALK), c-Met (hepatocyte growth factor receptor), and oncogenic c-ros oncogene1 (ROS1: RTK class orphan) fusion kinase FIG (fused in GB)-ROS1. As such, these could be attractive targets for GB therapy. The study subjects consisted of 19 patients who underwent neurosurgical resection of GB tissues. Our in vitro and ex vivo models promisingly demonstrated that treatments with crizotinib (PF-02341066: dual ALK/c-Met inhibitor) and temozolomide in combination induced synergistic antitumor activity on FIG-ROS1-positive GB cells. Our results also showed that ex vivo FIG-ROS1+ slices (obtained from GB patients) when cultured were able to preserve tissue architecture, cell viability, and global gene-expression profiles for up to 14 days. Both in vitro and ex vivo studies indicated that combination blockade of FIG, p-ROS1, p-ALK, and p-Met augmented apoptosis, which mechanistically involves activation of Bim and inhibition of survivin, p-Akt, and Mcl-1 expression. However, it is important to note that we did not see any significant synergistic effect of crizotinib and temozolomide on FIG-ROS1-negative GB cells. Thus, these ex vivo culture results will have a significant impact on patient selection for clinical trials and in predicting response to crizotinib and temozolomide therapy. Further studies in different animal models of FIG-ROS1-positive GB cells are warranted to determine useful therapies for the management of human GBs.

APA, Harvard, Vancouver, ISO, and other styles

16

Navarro-Torné, Adoración, Daniel Curcio, Jennifer C. Moïsi, and Luis Jodar. "Burden of invasive group B Streptococcus disease in non-pregnant adults: A systematic review and meta-analysis." PLOS ONE 16, no. 9 (September 30, 2021): e0258030. http://dx.doi.org/10.1371/journal.pone.0258030.

Full text

Abstract:

Background Streptococcus agalactiae or group B Streptococcus (GBS) has emerged as an important cause of invasive disease in adults, particularly among the elderly and those with underlying comorbidities. Traditionally, it was recognised as an opportunistic pathogen colonising and causing disease in pregnant women, neonates, and young infants. Reasons for the upsurge of invasive GBS (iGBS) among the elderly remain unclear, although it has been related to risk factors such as underlying chronic diseases, immunosenescence, impaired inflammatory response, and spread of virulent clones. Antibiotics are successfully as treatment or prophylaxis against iGBS. Several candidate vaccines against iGBS are under development. Objectives To conduct a systematic review of the current literature on invasive GBS in order to determine disease incidence and case fatality ratio (CFR) among non-pregnant adults. Additionally, information on risk factors, clinical presentation, serotype distribution, and antimicrobial resistance was also retrieved. Methods Between January and June 2020, electronic searches were conducted in relevant databases: MEDLINE, EMBASE, Global Health, and SCOPUS. Studies were included in the systematic review if they met the inclusion/exclusion criteria. The authors assessed the selected studies for relevance, risk of bias, outcome measures, and heterogeneity. Meta-analyses on incidence and CFR were conducted after evaluating the quality of methods for assessment of exposure and outcomes. Results Pooled estimates of iGBS incidence in non-pregnant adults 15 years and older were 2.86 cases per 100.000 population (95% CI, 1.68–4.34). Incidence rates in older adults were substantially higher, 9.13 (95%CI, 3.53–17.22) and 19.40 (95%CI, 16.26–22.81) per 100.000 population ≥50 and ≥ 65 years old, respectively. Incidence rates ranged from 0.40 (95% CI, 0.30–0.60) in Africa to 5.90 cases per 100.000 population (95% CI, 4.30–7.70) in North America. The overall CFR was and 9.98% (95% CI, 8.47–11.58). CFR was highest in Africa at 22.09% (95% CI, 12.31–33.57). Serotype V was the most prevalent serotype globally and in North America accounting for 43.48% (n = 12926) and 46,72% (n = 12184) of cases, respectively. Serotype Ia was the second and serotype III was more prevalent in Europe (25.0%) and Asia (29.5%). Comorbidities were frequent among non-pregnant adult iGBS cases. Antimicrobial resistance against different antibiotics (i.e., penicillin, erythromycin) is increasing over time. Conclusions This systematic review revealed that iGBS in non-pregnant adults has risen in the last few years and has become a serious public health threat especially in older adults with underlying conditions. Given the current serotype distribution, vaccines including serotypes predominant among non-pregnant adults (i.e., serotypes V, Ia, II, and III) in their formulation are needed to provide breadth of protection. Continued surveillance monitoring potential changes in serotype distribution and antimicrobial resistance patterns are warranted to inform public health interventions.

APA, Harvard, Vancouver, ISO, and other styles

17

Stebner, B., C. Vasquez, D. Grigat, C. Joseph, E. Lang, G. Kaplan, and K. Novak. "P117: Emergency physicians are choosing wisely when transfusing patients with non-variceal upper gastrointestinal bleeding and hemoglobins >70 g/L." CJEM 19, S1 (May 2017): S117—S118. http://dx.doi.org/10.1017/cem.2017.319.

Full text

Abstract:

Introduction: Acute non-variceal upper gastrointestinal bleeding (NVUGIB) is a common presentation to the Emergency Department (ED) associated with significant mortality and morbidity. Recent evidence suggests that overt-transfusion is associated with poor patient outcomes and that stable patients above a hemoglobin (hgb) above 70 g/L should be transfused judiciously. This retrospective health records review aims to determine the proportion of NVUGIB patients with hemoglobin greater than 70 g/L who were still appropriately transfused based on clinical parameters. Methods: A retrospective review was conducted on randomly selected patients that presented to one of two major tertiary hospitals with a primary diagnosis of NVUGIB who received blood products, despite a presenting hemoglobin >70 g/L. Standardized case report forms were developed through chart abstraction using a pilot-tested template. The appropriateness of transfusion was then adjudicated separately by a trained medical student and an emergency physician; discrepancies were resolved by discussion. Results: Following independent review of the charts, agreement was met on 94% (45/48) of the charts and after collective discussion 100% consensus was reached and all 48 patients’ transfusion appropriateness and categorized into one of three groups: Appropriate, Potentially avoidable, and clearly avoidable. Only in 22.9% (11/48) of the cases was transfusion deemed to be clearly avoidable while emergency physicians appropriately transfused 45.8% (22/48) of patients based on clinical status and other factors. In 31.3% (15/48) of the cases, transfusion was potentially avoidable in favor of other management options. We calculated the mean GBS for the appropriate, potentially avoidable, and clearly avoidable categories yielding 12.8, 12.7, and 10.2 respectively. Mortality occurred in 2 of the 48 cases (4%). Conclusion: In most instances, emergency physicians are effectively integrating hemoglobin thresholds and clinical status to determine if a patients with NVUGIB and hgb >70 require blood products.

APA, Harvard, Vancouver, ISO, and other styles

18

Sanders, David, Sean Dalrymple, Myles Poulin, Ruixiang Zheng, and Todd Lowary. "Structural Studies of an Novel Sugar Nucleotide Pyranose-Furanose Mutase." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C477. http://dx.doi.org/10.1107/s2053273314095229.

Full text

Abstract:

Campylobacter jejuni (Cjj) is the leading cause of gastroenteritis in humans, its glycoconjugates are known to include sugars in the furanose ring conformation. In particular, Cjj HS:41 strains are associated with the development of Guillian-Barré syndrome (GBS) and produce a key virulence factor of the bacterium, namely furanose-based capsular polysaccharides (CPS). To date, the enzymes responsible for furanose biosynthesis in Cjj HS:41 CPS are poorly understood. CPS sequencing has revealed three genes, annotated as glf1-3 via homology to known bacterial UDP-D-galactopyranose mutase (UGM), could be involved in the biosynthetic pathways. Our laboratories are interested in the structure-function relationship behind recognition and discrimination within such pyranose-furanose mutases. Enzymology studies have shown Glf1 is a flavoprotein responsible for isomerization between GDP-6d-D-altro-heptopyranose and GDP-6d-D-altro-heptofuranose, the latter being a major component of CPS. This GDP-altro-heptopyranose mutase (GaHM) activity is the first example of a heptose-recognizing mutase. Given that many of the UGM active site and FAD binding site residues are conserved in GaHM, the catalytic mechanism is likely similar to that of UGM. In order to establish key features of the enzyme, detailed structural information is required. We report here on the structure of Cjj GaHM, which has been co-crystallized with GDP, in both oxidized and reduced states. Due to low sequence identity with bacterial UGMs, Se-MET SAD phasing was ultimately employed to solve the structure. We will also discuss our recent crystallization efforts with Cjj GaHM in the presence of GDP-sugar substrate derivatives. Ultimately, the structural information gleaned from this study could lead to the identification of a new inhibitors targeting the CPS biosynthetic pathway.

APA, Harvard, Vancouver, ISO, and other styles

19

Kobayashi, Miwako, Lesley McGee, Sopio Chochua, Mirasol Apostol, Nisha B. Alden, Monica M. Farley, Lee Harrison, et al. "85. Characterization of Group B streptococcus Strains with Reduced Susceptibility to Beta-lactam Antibiotics, Active Bacterial Core Surveillance, 1998–2017." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S173—S174. http://dx.doi.org/10.1093/ofid/ofaa439.395.

Full text

Abstract:

Abstract Background In the United States, approximately 30,000 invasive group B Streptococcus (iGBS) infections occur annually; beta-lactam antibiotics (BL) are the first choice for prevention in young infants and treatment in all age groups. We obtained phenotypic and genotypic data for iGBS isolates from U.S. population-based surveillance sites to describe the emergence and characteristics of strains with reduced beta-lactam susceptibility (RS) over a 20-year period. Methods We analyzed RS iGBS isolates from eight Active Bacterial Core surveillance sites from 1998–2017. Through 2014, minimum inhibitory concentrations (MIC) for six BL were determined by broth microdilution, followed by whole genome sequencing (WGS) of RS isolates exceeding pre-defined breakpoints (Table 1). In 2015, WGS and MIC testing were performed for all isolates. After 2015, all isolates underwent WGS. MIC testing was continued on approximately 25% of isolates; otherwise, only those with modified penicillin binding protein (PBP) 2x transpeptidase amino acid sequence types or suboptimal WGS (< 1 % of isolates) underwent MIC testing. Clinical information on RS cases was abstracted from medical charts. Results Of 26,058 out of 27,269 iGBS isolates (95.6%) tested to date, 107 (0.4%) exhibited RS, increasing from 0% in 1998 to a peak of 1.1% in 2016 (P< 0.05 for trend) (Figure 1). Seven (6.5%) RS strains were from infants aged < 90 days; the rest were from adults aged ≥30 years (Table 2). RS strains consisted of 52 PBP2x types with diverse susceptibility patterns (Table 1). Seven RS strains (6.5%) had wild-type (non-modified) PBP2x; all met the RS criteria based on a single cephalosporin with a confirmed (repeated) MIC value at the break point (Table 1). Compared to non-RS strains, RS strains were more common in patients who presented with cellulitis and osteomyelitis and with underlying conditions such as diabetes or chronic skin breakdown (Table 2). Of 82 (85.4%) patients with RS strains and additional clinical information, 8.3% had known prior GBS infection; 26.8% had known BL exposure in the preceding year. Conclusion Preliminary results show that RS increased in recent years; strains RS to penicillin and ampicillin remain low. Variable pbp2x mutations have emerged and predominant strains have not yet been identified. Disclosures Nisha B. Alden, MPH, CDC (Grant/Research Support) Lee Harrison, MD, Dynavax (Consultant)GSK (Consultant)Merck (Consultant)OMVax (Consultant)Pfizer (Consultant)Sanofi Pasteur (Consultant)

APA, Harvard, Vancouver, ISO, and other styles

20

Ahmed, Sk Shafi. "Fuel Options for Bangladesh-2017." Journal of Chemical Engineering 30, no. 1 (December 7, 2017): 27–31. http://dx.doi.org/10.3329/jce.v30i1.34794.

Full text

Abstract:

Fuel is an essential commody supporting our daily life and economy. Until today, the majority of Bangladesh fuel is met from domestic natural gas production. With economy growing (like GDP 7+ %) in coming years, fuel use is also increasing and the local gas prodcution could not meet the requirement. Goverment has already taken steps for the import of LNG and LPG to support the shortfall. This paper describes different fuel options and suggests that the additional fuel requirement might be met with the imported LNG considering the environmental and cost of fuel. LPG is costly than imported LNG. So, emphasis on LPG use may be considered only to the areas where there is no pipe gas supply.Journal of Chemical Engineering, Vol. 30, No. 1, 2017: 27-31

APA, Harvard, Vancouver, ISO, and other styles

21

DE CLERQ, Lode. "De internationale context van de Belgische verwarmingstechnologie in haar relatie met de architectuur." Gentse Bijdragen tot de Interieurgeschiedenis 32 (January 1, 2003): 77–112. http://dx.doi.org/10.2143/gbi.32.0.563114.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

方, 永锋. "Design of Digital Gas Meter Based on Processor STC89C52." Mechanical Engineering and Technology 05, no. 01 (2016): 17–21. http://dx.doi.org/10.12677/met.2016.51003.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Gutleb, D. R., C. Roos, A. Noll, J. Ostner, and O. Schülke. "COMT Val158 Met moderates the link between rank and aggression in a non-human primate." Genes, Brain and Behavior 17, no. 4 (December 20, 2017): e12443. http://dx.doi.org/10.1111/gbb.12443.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Hasan, Masroor, and Charles Neill. "Assessing Pipeline Adequacy to Meet Natural Gas Demand for Electricity Generation: New York State Case Study." Transportation Research Record: Journal of the Transportation Research Board 1833, no. 1 (January 2003): 47–56. http://dx.doi.org/10.3141/1833-07.

Full text

Abstract:

A conceptual framework and modeling approach are presented for assessing pipeline adequacy to meet existing and future demands for natural gas in electricity generation after gas demands for traditional end users have been met. Transportation logistics and economics issues are identified that natural gas (and electric) suppliers face in trying to meet traditional and electricity generation gas demands. An integrated electric and gas modeling approach is used for this purpose. The approach uses separate models for electric and gas systems. Consistent equilibrium solutions are obtained by iterating between the two models. The economic decisions and logistical issues facing the gas and electric industries are quite stark. The incentives of the two industries need to be realigned to achieve greater electric efficiency, reliable generation, and better air quality at a reasonable cost. As a detailed case study of the modeling approach, results are presented from an analysis of the ability of the natural gas delivery system to meet future electricity generation requirements in New York State. The analysis integrates the modeling of the gas demands of New York State electric generators with the modeling of available gas supply and delivery capacity to the state. Although the analysis indicates that the gas and electric systems in New York can reliably meet their future loads under a range of electricity generation and gas pipeline expansion scenarios, oil use by electric generators remains a key substitute for gas during times of peak gas demands (e.g., cold winter days).

APA, Harvard, Vancouver, ISO, and other styles

25

Espinosa, F., R. Avila, S. S. Raza, A. Basit, and J. G. Cervantes. "Turbulent dispersion of a gas tracer in a nocturnal atmospheric flow." Meteorological Applications 20, no. 3 (January 30, 2012): 338–48. http://dx.doi.org/10.1002/met.1292.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

冯, 仲. "Gas Seal Leakage’s Analysis and Improvement of 4M50 New Hydrogen Compressor." Mechanical Engineering and Technology 01, no. 04 (2012): 57–60. http://dx.doi.org/10.12677/met.2012.14011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

付, 文耀. "Development and Application of Multi-Function Casing Gas Recovery Device at Wellhead." Mechanical Engineering and Technology 10, no. 02 (2021): 138–44. http://dx.doi.org/10.12677/met.2021.102016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

盛, 选禹. "Steady-State Analysis of Gas Flow Field in Anti-Sulfur High-Pressure Separator." Mechanical Engineering and Technology 03, no. 03 (2014): 124–30. http://dx.doi.org/10.12677/met.2014.33016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Webb, V. N. "Gesprek met prof. G.S. Nienaber: 12 November 1988." South African Journal of Linguistics 6, no. 4 (January 1988): 1–11. http://dx.doi.org/10.1080/10118063.1988.9723769.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Wincel, H., and R. H. Fokkens. "Gas-phase ion chemistry of Glu/Met systems." Rapid Communications in Mass Spectrometry 16, no. 1 (2001): 15–26. http://dx.doi.org/10.1002/rcm.540.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Meyer, N. R., A. L. Zerkle, and D. A. Fike. "Sulphur cycling in a Neoarchaean microbial mat." Geobiology 15, no. 3 (January 27, 2017): 353–65. http://dx.doi.org/10.1111/gbi.12227.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Reynolds, Christian J., Graham W. Horgan, Stephen Whybrow, and Jennie I. Macdiarmid. "Healthy and sustainable diets that meet greenhouse gas emission reduction targets and are affordable for different income groups in the UK." Public Health Nutrition 22, no. 8 (February 20, 2019): 1503–17. http://dx.doi.org/10.1017/s1368980018003774.

Full text

Abstract:

AbstractObjectiveTo model dietary changes required to shift the UK population to diets that meet dietary recommendations for health, have lower greenhouse gas emissions (GHGE) and are affordable for different income groups.DesignLinear programming was used to create diets that meet dietary requirements for health and reduced GHGE (57 and 80 % targets) by income quintile, taking account of food budgets and foods currently purchased, thereby keeping dietary change to a minimum.Setting/ParticipantsNutrient composition, GHGE and price data were mapped to 101 food groups in household food purchase data (UK Living Cost and Food Survey (2013), 5144 households).ResultsCurrent diets of all income quintiles had similar total GHGE, but the source of GHGE differed by types of meat and amount of fruit and vegetables. It was possible to create diets with a 57 % reduction in GHGE that met dietary and cost restraints in all income groups. In the optimised diets, the food sources of GHGE differed by income group due to the cost and keeping the level of deviation from current diets to a minimum. Broadly, the changes needed were similar across all groups; reducing animal-based products and increasing plant-based foods but varied by specific foods.ConclusionsHealthy and lower-GHGE diets could be created in all income quintiles but tailoring changes to income groups to minimise deviation may make dietary changes more achievable. Specific attention must be given to make interventions and policies appropriate for all income groups.

APA, Harvard, Vancouver, ISO, and other styles

33

Gong, Shao Run, Yue Jin Wang, Guang Ping Zhang, Guo Ping Zhan, Bing Zou, Li Li, and Tao Liu. "Design and Experiment of Fumigant Gas Trace Detection System Based on Photoionization." Advanced Materials Research 1037 (October 2014): 129–33. http://dx.doi.org/10.4028/www.scientific.net/amr.1037.129.

Full text

Abstract:

To meet the requirements, based on the provision of Administration of Quality Supervision, Inspection and Quarantine (AQSIQ), of gas leakage monitoring inside dosing room of fumigant warehouse at the inspection and quarantine port, a fumigant gas trace detection system (FGTDS) based on photoionization detector (PID) is developed. The principle, structure and characteristic of the system design are especially demonstrated. The test data under different temperature, relative humidity (RH) and methyl bromide concentration demonstrate that the FGTDS based on PID can measure methyl bromide under very low concentration. A conclusion can be drawn that the requirements of gas leakage monitoring inside dosing room of fumigation warehouse at the inspection and quarantine port can be met through further proper design.

APA, Harvard, Vancouver, ISO, and other styles

34

杨, 廷毅. "Effects of Materials and Geometric Dimensions on the Flying Characteristics of a Slider in Gas-Filled Hard Disk Drives." Mechanical Engineering and Technology 06, no. 03 (2017): 240–49. http://dx.doi.org/10.12677/met.2017.63030.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

叶, 德才. "Research on the Lever Type and Internal Balance Bar Type Low to Low Gas Pressure Regulating Installation Performance Difference." Mechanical Engineering and Technology 09, no. 05 (2020): 498–509. http://dx.doi.org/10.12677/met.2020.95054.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Lock, Reinier. "Nafta: More 1993 possibilities than meet the eye." Natural Gas 9, no. 6 (August 20, 2008): 1–5. http://dx.doi.org/10.1002/gas.3410090602.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Ding, Xianjun, Hong Jiang, Xingyue Hu, Hong Ren, and Huaying Cai. "Guillain-Barré syndrome and Low back pain: two cases and literature review." Open Medicine 13, no. 1 (October 22, 2018): 503–8. http://dx.doi.org/10.1515/med-2018-0074.

Full text

Abstract:

AbstractPurpose. To describe the clinical, electrophysiological, and lumbar magnetic resonance imaging (MRI) features of two cases of atypical Guillain-Barré syndrome (GBS). Methods We reported two GBS variant cases with initial and prominent symptoms of low back pain. We analysed their clinical, electrophysiological, and lumbar MRI features. Results Two patients with GBS reported low back pain as the initial and prominent symptom, which was not accompanied by limb weakness. The electrophysiological study showed abnormal F-waves in the common peroneal and tibial nerves, and acute polyradiculoneuropathy in the cauda equina. Examination of the cerebrospinal fluid (CSF) showed albuminocytologic dissociation. Serum was positive for GQ1b-IgM antibodies. Lumbar MRI showed gadolinium enhancement of the nerve roots and cauda equina. A standard regime of intravenous immunoglobulin markedly alleviated the low back pain. Conclusions Low back pain caused by GBS should be differentiated from other diseases. This initial or early prominent symptom may delay the diagnosis of GBS; therefore, it is important to conduct a detailed electrophysiological, CSF, and gadolinium-enhanced lumbar MRI analysis.

APA, Harvard, Vancouver, ISO, and other styles

38

Nishida, Masahiro, Atsushi Shimizu, Toshitaka Tsuda, Christian Rocken, and Randolph H. Ware. "Seasonal and Longitudinal Variations in the Tropical Tropopause Observed with the GPS Occultation Technique (GPS/MET)." Journal of the Meteorological Society of Japan. Ser. II 78, no. 6 (2000): 691–700. http://dx.doi.org/10.2151/jmsj1965.78.6_691.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Giunta, G., R. Vernazza, R. Salerno, A. Ceppi, G. Ercolani, and M. Mancini. "Hourly weather forecasts for gas turbine power generation." Meteorologische Zeitschrift 26, no. 3 (June 14, 2017): 307–17. http://dx.doi.org/10.1127/metz/2017/0791.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Wei, Xianggeng, Fei Qin, Lei Shi, Baoqing Zhang, and Guoqiang He. "Design and Experimental Investigation on Gas Oxygen/Kerosene Ejector Rocket for RBCC Application." Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University 36, no. 3 (June 2018): 558–64. http://dx.doi.org/10.1051/jnwpu/20183630558.

Full text

Abstract:

The ejector rocket is one of the core components of the rocket based combined cycle propulsion system, and must be capable of variable working conditions. In order to meet technical requirements for RBCC application, the variable duty operating ejector rocket using the gas Oxygen/Kerosene was designed based on the gas pressurized propellant feed systems. Hot firing tests of four different working conditions had been completed. Experimental results show that the designed ejector rocket engine was stable and reliable, and the working parameters met the design requirements, and the working conditions were adjusted quickly. It lays a foundation for the study of the RBCC engine test and the engine technology of large adjustment ratio.

APA, Harvard, Vancouver, ISO, and other styles

41

Sancho-Bastos, Francisco, and Horacio Perez-Blanco. "Cogeneration System Simulation and Control to Meet Simultaneous Power, Heating, and Cooling Demands." Journal of Engineering for Gas Turbines and Power 127, no. 2 (April 1, 2005): 404–9. http://dx.doi.org/10.1115/1.1789993.

Full text

Abstract:

Gas turbines are projected to meet increasing power demand throughout the world. Cogeneration plants hold the promise of increased efficiency at acceptable cost. In a general case, a cogen plant could be able to meet power, heating and cooling demands. Yet those demands are normally uncoupled. Control and storage strategies need to be explored to ensure that each independent demand will be met continuously. A dynamic model of a mid-capacity system is developed, including gas and steam turbines, two heat recovery steam generators (HRSG) and an absorption-cooling machine. Controllers are designed using linear quadratic regulators (LQR) to control two turbines and a HRSG with some novelty. It is found that the power required could be generated exclusively with exhaust gases, without a duct burner in the high-pressure HRSG. The strategy calls for fuel and steam flow rate modulation for each turbine. The stability of the controlled system and its performance are studied and simulations for different demand cases are performed.

APA, Harvard, Vancouver, ISO, and other styles

42

Burton, R. R., J. Dudhia, A. M. Gadian, and S. D. Mobbs. "The use of a numerical weather prediction model to simulate the release of a dense gas with an application to the Lake Nyos disaster of 1986." Meteorological Applications 24, no. 1 (December 29, 2016): 43–51. http://dx.doi.org/10.1002/met.1603.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

O'Connor, David. "New England Can Import Canadian Hydropower to Meet Environmental Goals." Natural Gas & Electricity 32, no. 5 (November 20, 2015): 23–28. http://dx.doi.org/10.1002/gas.21873.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Bansal, Saurabh, Kody Burden, and Brandon Swartout. "Utilities Can Improve Customer Experience to Meet Growing Customer Expectations." Climate and Energy 37, no. 3 (September 9, 2020): 9–18. http://dx.doi.org/10.1002/gas.22194.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Spellman, Richard F. "Market transformation programs help utilities meet customer needs, environmental challenges." Natural Gas 16, no. 2 (January 9, 2007): 12–16. http://dx.doi.org/10.1002/gas.3410160204.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Burow, L. C., D. Woebken, I. P. G. Marshall, S. W. Singer, J. Pett-Ridge, L. Prufert-Bebout, A. M. Spormann, B. M. Bebout, P. K. Weber, and T. M. Hoehler. "Identification ofDesulfobacteralesas primary hydrogenotrophs in a complex microbial mat community." Geobiology 12, no. 3 (April 15, 2014): 221–30. http://dx.doi.org/10.1111/gbi.12080.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Bakhashwain, A., S. Sallam, and A. Allam. "Nutritive Value Assessment of Some Saudi ArabianFoliages by Gas Production Technique in vitro." Journal of King Abdulaziz University-Meteorology, Environment and Arid Land Agriculture Sciences 21, no. 1 (2010): 65–80. http://dx.doi.org/10.4197/met.21-1.5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Wang, Y., J. Li, C. Chen, C. Chen, B. Zhu, R. K. Moysis, X. Lei, et al. "COMT rs4680 Met is not always the ‘smart allele’: Val allele is associated with better working memory and larger hippocampal volume in healthy Chinese." Genes, Brain and Behavior 12, no. 3 (February 20, 2013): 323–29. http://dx.doi.org/10.1111/gbb.12022.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

仲, 冯. "4M50型新氢压缩机气封泄露原因分析及改进Gas Seal Leakage’s Analysis and Improvement of 4M50 New Hydrogen Compressor." Mechanical Engineering and Technology 01, no. 04 (2012): 57–60. http://dx.doi.org/10.4236/met.2012.14011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Löwisch, Henriette. "An Interview with Alice Schwarzer on Leni Riefenstahl." German Politics and Society 31, no. 3 (September 1, 2013): 76–82. http://dx.doi.org/10.3167/gps.2013.310304.

Full text

Abstract:

Alice Schwarzer’s name is synonymous with the second-wave women’smovement in West Germany, and when she picks a fight, the odds are ashouting match will follow. Admired by some, reviled by others, West Germany’sbest-known feminist has often used controversy to amplify theactivist journalism she has pursued since the late 1960s. She is opinionated,combative, and unpredictable—attributes all reflected in her 1999 essay onLeni Riefenstahl, which the interview below revisits. Her sympathetic portrayalof the filmmaker met with criticism, which is certainly consistent withthe affinity toward ambivalence Schwarzer has demonstrated throughouther career as an author, activist and talk show celebrity.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!