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Journal articles on the topic 'GE-180'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Boutin, Hervé, Katie Murray, Jesus Pradillo, et al. "[18F]GE-180: a novel TSPO radiotracer compared to [11C]PK11195 in a preclinical model of stroke." Eur J Nucl Med Mol Imaging 42, no. 3 (2014): 503–11. https://doi.org/10.1007/s00259-014-2939-8.

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PURPOSE: Neuroinflammation plays a critical role in various neuropathological conditions, and hence there is renewed interest in the translocator protein (TSPO) as a biomarker of microglial activation and macrophage infiltration in the brain. This is reflected in the large amount of research conducted seeking to replace the prototypical PET radiotracer 11C-R-PK11195 with a TSPO ligand with higher performance. Here we report the in vivo preclinical investigation of the novel TSPO tracer 18F-GE-180 in a rat model of stroke. METHODS: Focal cerebral ischaemia was induced in Wistar rats by 60-min o

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2

Hellberg, Sanna, Heidi Liljenbäck, Olli Eskola, et al. "Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)." Contrast Media & Molecular Imaging 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/9186902.

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Intraplaque inflammation plays an important role in the progression of atherosclerosis. The 18 kDa translocator protein (TSPO) expression is upregulated in activated macrophages, representing a potential target to identify inflamed atherosclerotic plaques. We preclinically evaluated 18F-GE-180, a novel third-generation TSPO radioligand, in a mouse model of atherosclerosis. Methods. Nine hypercholesterolemic mice deficient in low density lipoprotein receptor and apolipoprotein B48 (LDLR−/−ApoB100/100) and six healthy C57BL/6N mice were injected with 10 MBq of 18F-GE-180. Specificity of binding

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Holzgreve, Adrien, Dennis Pötter, Matthias Brendel, et al. "Longitudinal [18F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model." Biomedicines 10, no. 4 (2022): 738. http://dx.doi.org/10.3390/biomedicines10040738.

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The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). Here, we investigated TSPO PET imaging and autoradiography in the frequently used GL261 glioblastoma mouse model and aimed to generate insights into the temporal evolution of TSPO radioligand uptake in glioblastoma in a preclinical setting. We performed a longitudinal [18F]GE-180 PET imaging study from day 4 to 14 post inoculation in the orthotopic syngeneic GL261 GBM mouse model (n = 21 GBM mice, n = 3 sham mice). Contrast-enhanced computed tomography (CT) was perf

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4

Nik Azmi, Nik Nur Ashirah, Thuan Chew Tan, May Yen Ang, Yong Foo Wong, and Yin-Hui Leong. "Monitoring changes in 3-monochloropropanediol, 2-monochloropropanediol, and glycidyl esters of palm olein after repeated deep frying of commercial chicken nuggets." International Food Research Journal 31, no. 6 (2024): 1591–604. https://doi.org/10.47836/ifrj.31.6.17.

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The present work examined the changes in 3-monochloropropanediol ester (3-MCPDE), 2-monochloropropanediol ester (2-MCPDE), and glycidyl ester (GE) in palm olein after repeated deep frying of commercial chicken nugget samples at 160 and 180°C. Free fatty acid (FFA) composition, p-anisidine value (p-AV), and specific extinction at 232 and 268 nm (K232 and K268) were determined. Results indicated that the concentrations of MCPDEs and GE in the frying oil after the fourth frying cycle were higher than the initial concentrations, except for the GE concentration when fried at 180°C. The content of 3

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5

Buchert, Ralph, Meike Dirks, Christian Schütze, et al. "Reliable quantification of 18F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio." European Journal of Nuclear Medicine and Molecular Imaging 47, no. 12 (2020): 2887–900. http://dx.doi.org/10.1007/s00259-020-04810-1.

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Abstract Purpose Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of microglia activation by PET with the translocator protein (TSPO) ligand 18F-GE-180. This study tested simplified methods for quantification of 18F-GE-180 PET. Methods Dynamic 18F-GE-180 PET with arterial blood sampling and metabolite correction was performed in five healthy volunteers and 20 liver-transplanted patients. Population-based input function templates were generate

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Dickens, Alex M., Susanne Vainio, Päivi Marjamäki, et al. "Detection of Microglial Activation in an Acute Model of Neuroinflammation Using PET and Radiotracers 11C-(R)-PK11195 and 18F-GE-180." J Nucl Med. 55, no. 3 (2014): 466–72. https://doi.org/10.2967/jnumed.113.125625.

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It remains unclear how different translocator protein (TSPO) ligands reflect the spatial extent of astrocyte or microglial activation in various neuroinflammatory conditions. Here, we use a reproducible lipopolysaccharide (LPS)-induced model of acute central nervous system inflammation to compare the binding performance of a new TSPO ligand (18)F-GE-180 with (11)C-(R)-PK11195. Using immunohistochemistry, we also explore the ability of the TSPO ligands to detect activated microglial cells and astrocytes. METHODS: Lewis rats (n = 30) were microinjected with LPS (1 or 10 μg) or saline (1 μL

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López-Picón, Francisco, Anniina Snellman, Olli Eskola, et al. "Neuroinflammation appears early and then plateaus in a mouse model of Alzheimer's disease shown by PET imaging." Journal of Nuclear Medecine 59, no. 3 (2017): 509–15. https://doi.org/10.2967/jnumed.117.197608.

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<strong>Abstract</strong> <strong>Rationale:</strong> Neuroinflammation has been associated with different neurological diseases including Alzheimer's disease (AD). In AD, the translocator protein 18kDa (TSPO) is overexpressed in the activated microglia that surround the β-amyloid plaques. In the current longitudinal study, using a mouse model of AD, we evaluated the association between β-amyloid deposition and neuroinflammation in AD. <strong>Methods:</strong> To monitor the longitudinal changes in β-amyloid deposition and neuroinflammation, we used in vivo PET imaging and

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8

Vettermann, Franziska J., Stefanie Harris, Julia Schmitt, et al. "Impact of TSPO Receptor Polymorphism on [18F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders." Life 11, no. 6 (2021): 484. http://dx.doi.org/10.3390/life11060484.

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TSPO-PET tracers are sensitive to a single-nucleotide polymorphism (rs6971-SNP), resulting in low-, medium- and high-affinity binders (LABs, MABs and HABS), but the clinical relevance of [18F]GE-180 is still unclear. We evaluated the impact of rs6971-SNP on in vivo [18F]GE-180 binding in a healthy brain and in pseudo-reference tissue in neuro-oncological and neurodegenerative diseases. Standardized uptake values (SUVs) of [18F]GE-180-PET were assessed using a manually drawn region of interest in the frontoparietal and cerebellar hemispheres. The SUVs were compared between the LABs, MABs and HA

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9

Gold, Lukas, Enio Barci, Matthias Brendel, et al. "The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma." Biomedicines 12, no. 1 (2024): 188. http://dx.doi.org/10.3390/biomedicines12010188.

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Background: The translocator protein (TSPO) has been proven to have great potential as a target for the positron emission tomography (PET) imaging of glioblastoma. However, there is an ongoing debate about the potential various sources of the TSPO PET signal. This work investigates the impact of the inoculation-driven immune response on the PET signal in experimental orthotopic glioblastoma. Methods: Serial [18F]GE-180 and O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) PET scans were performed at day 7/8 and day 14/15 after the inoculation of GL261 mouse glioblastoma cells (n = 24) or saline (sh

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10

Sridharan, Sujata, Francois-Xavier Lepelletier, William Trigg, et al. "Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats." Molecular Imaging & Biology 19 (August 1, 2016): 77–89. https://doi.org/10.1007/s11307-016-0984-3.

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PURPOSE: Over the past 20 years, neuroinflammation (NI) has increasingly been recognised as having an important role in  many neurodegenerative diseases, including Alzheimer's disease. As such, being able to image NI non-invasively in patients is critical to monitor pathological processes and potential therapies targeting neuroinflammation. The translocator protein (TSPO) has proven a reliable NI biomarker for positron emission tomography (PET) imaging. However, if TSPO imaging in acute conditions such as stroke provides strong and reliable signals, TSPO imaging in neurodegenerat

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Jalleh, Ryan, Hung Pham, Chinmay S. Marathe, et al. "Acute Effects of Lixisenatide on Energy Intake in Healthy Subjects and Patients with Type 2 Diabetes: Relationship to Gastric Emptying and Intragastric Distribution." Nutrients 12, no. 7 (2020): 1962. http://dx.doi.org/10.3390/nu12071962.

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Glucagon-like peptide-1 receptor agonists induce weight loss, which has been suggested to relate to the slowing of gastric emptying (GE). In health, energy intake (EI) is more strongly related to the content of the distal, than the total, stomach. We evaluated the effects of lixisenatide on GE, intragastric distribution, and subsequent EI in 15 healthy participants and 15 patients with type 2 diabetes (T2D). Participants ingested a 75-g glucose drink on two separate occasions, 30 min after lixisenatide (10 mcg) or placebo subcutaneously, in a randomised, double-blind, crossover design. GE and

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12

Минтаиров, С. А., В. М. Емельянов, Н. А. Калюжный та В. М. Андреев. "Просветление поверхности субэлемента на основе германия в каскадных GaInP/GaAs/Ge-солнечных элементах". Письма в журнал технической физики 44, № 22 (2018): 95. http://dx.doi.org/10.21883/pjtf.2018.22.46927.17464.

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AbstractSpectral characteristics of the Ge subcell of triple-junction GaInP/GaAs/Ge solar cells have been simulated. It was shown that using a GaInP nucleation layer that creates a shallow diffusion p – n junction in Ge can raise the photogeneration current of the Ge subcell by ~4.5 mA/cm^2 as compared with the value in the case of a GaAs nucleation layer. The optimal thickness of the GaInP layer (170–180 nm) makes it possible to additionally raise the photocurrent by ~1.5 mA/cm^2. It was experimentally demonstrated that the photogenerated current of the Ge subcell of GaInP/GaAs/Ge solar cells

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13

Kuo, Wei-Cheng, Hung-Chi Hsieh, Wu Chih-Hung, Huang Wen-Hsiang, Chien-Chieh Lee, and Jenq-Yang Chang. "High Quality GaAs Epilayers Grown on Si Substrate Using 100 nm Ge Buffer Layer." International Journal of Photoenergy 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/7218310.

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We present high quality GaAs epilayers that grow on virtual substrate with 100 nm Ge buffer layers. The thin Ge buffer layers were modulated by hydrogen flow rate from 60 to 90 sccm to improve crystal quality by electron cyclotron resonance chemical vapor deposition (ECR-CVD) at low growth temperature (180°C). The GaAs and Ge epilayers quality was verified by X-ray diffraction (XRD) and spectroscopy ellipsometry (SE). The full width at half maximum (FWHM) of the Ge and GaAs epilayers in XRD is 406 arcsec and 220 arcsec, respectively. In addition, the GaAs/Ge/Si interface is observed by transmi

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14

Fleischmann, D. F., M. Buettner, M. Unterrainer, et al. "18F-GE-180 TSPO PET in High-Grade Glioma RT Planning." International Journal of Radiation Oncology*Biology*Physics 111, no. 3 (2021): e589. http://dx.doi.org/10.1016/j.ijrobp.2021.07.1577.

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15

Langen, Karl-Josef, and Antje Willuweit. "TSPO PET using 18F-GE-180: a new perspective in neurooncology?" European Journal of Nuclear Medicine and Molecular Imaging 44, no. 13 (2017): 2227–29. http://dx.doi.org/10.1007/s00259-017-3838-6.

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Chang, Teng-Hsiang, Chiao Chang, Yen-Ho Chu, et al. "Low Temperature (180°C) Growth of Smooth Surface Germanium Epilayers on Silicon Substrates Using Electron Cyclotron Resonance Chemical Vapor Deposition." International Journal of Photoenergy 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/906037.

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This paper describes a new method to grow thin germanium (Ge) epilayers (40 nm) on c-Si substrates at a low growth temperature of 180°C using electron cyclotron resonance chemical vapor deposition (ECR-CVD) process. The full width at half maximum (FWHM) of the Ge (004) in X-ray diffraction pattern and the compressive stain in a Ge epilayer of 683 arcsec and 0.12% can be achieved. Moreover, the Ge/Si interface is observed by transmission electron microscopy to demonstrate the epitaxial growth of Ge on Si and the surface roughness is 0.342 nm. The thin-thickness and smooth surface of Ge epilayer

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Spilki, Fernando R., Alessandra D. Silva, Helena Beatriz C. Ruthner Batista, et al. "Field evaluation of safety during gestation and horizontal spread of a recombinant differential bovine herpesvirus 1 (BoHV-1) vaccine." Pesquisa Veterinária Brasileira 25, no. 1 (2005): 54–58. http://dx.doi.org/10.1590/s0100-736x2005000100010.

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Bovine herpesvirus type 1 (BoHV-1) is recognized as a major cause of respiratory, reproductive disease and abortion in cattle. Vaccination is widely applied to minimize losses induced by BoHV-1 infections; however, vaccination of dams during pregnancy with modified live virus (MLV) vaccines has been occasionally associated to abortions. We have previously reported the development of a BoHV-1 recombinant virus, constructed with basis on a Brazilian BoHV-1 (Franco et al. 2002a) from which the gene coding for glycoprotein E (gE) was deleted (gE-) by genetic manipulation. Such recombinant has been

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Völk, Stefanie, Marcus Unterrainer, Nathalie L. Albert, et al. "TSPO PET With 18F-GE-180 to Differentiate Variants of Multiple Sclerosis." Clinical Nuclear Medicine 45, no. 10 (2020): e447-e448. http://dx.doi.org/10.1097/rlu.0000000000003220.

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Abd Rahim, Alhan Farhanah, Nurul Syuhadah Mohd Razali, Rosfariza Radzali, Ainokhilah Mahmood, Irni Hamiza Hamzah, and Mohamed Fauzi Packeer Mohamed. "Enhanced Catalytic Palladium Embedded Inside Porous Silicon for Improved Hydrogen Gas Sensing." Sains Malaysiana 51, no. 12 (2022): 4087–98. http://dx.doi.org/10.17576/jsm-2022-5112-17.

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In this work, we reported on room temperature porous silicon (PS) and embedding PS using simple and economical techniques of electrochemical etching and thermal evaporation. The PS substrate was prepared using the technique of electrochemically etching the n-type Si (100) wafer at a constant current density of 10 mA/cm2 for 10 min under the illumination of incandescent white light. After PS formation, Ge pieces were thermally evaporated onto the two PS substrates in a vacuum condition. This was then followed by the deposition of the ZnO layer onto the Ge/PS substrate by the same method using c

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Zaumseil, P., A. Giussani, and T. Schroeder. "Laboratory-based characterization of heteroepitaxial structures: Advanced experiments not needing synchrotron radiation." Powder Diffraction 25, no. 2 (2010): 92–98. http://dx.doi.org/10.1154/1.3392302.

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It is demonstrated that a complex X-ray characterization of semiconductor films epitaxially grown on metal oxide buffer layers and Si(111) substrates is possible using laboratory-based equipment. This is demonstrated with epi-germanium on Pr2O3 as buffer material. Pole figure measurements prove that epi-Ge layers are nearly single crystalline with exactly the same in-plane orientation (type A) as the Si(111) substrate, while the lattice of the oxide layer is 180° rotated around the [111] surface normal (type B). Only a small fraction (less than 0.6 vol %) of the epi-Ge exhibits type B rotation

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Ji, Yingrui, Dongming Lan, Weifei Wang, Kok Ming Goh, Chin Ping Tan, and Yonghua Wang. "The Formation of 3-Monochloropropanediol Esters and Glycidyl Esters during Heat-Induced Processing Using an Olive-Based Edible Oil." Foods 11, no. 24 (2022): 4073. http://dx.doi.org/10.3390/foods11244073.

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With the prevalence of edible diacylglycerol (DAG) oil, which is beneficial to human, the generation of 3-monochloropropanediol esters (3-MCPDE) and glycidyl esters (GE) as well as the stability of physical properties during heat-induced processing still need to be explored. In this study, the experiment used olive-based edible oil with different contents of DAG (40, 60, and 80%) to make crackers and fry chicken. They were heated at 160 and 180 °C to determine the changes in 3-MCPDE and GE, the crackers’ hardness and gumminess, and the physical properties of the oil. During baking and frying,

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Nuringsih, Kartika. "ROLE OF GREEN ENTREPRENEURSHIP IN RAISING THE EFFECT OF GREEN VALUE TOWARD SUSTAINABLE DEVELOPMENT." International Journal of Economics, Business, and Entrepreneurship 3, no. 2 (2021): 29–46. http://dx.doi.org/10.23960/ijebe.v3i2.69.

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In line with circular economic, the role of green entrepreneurship (GE) should be useful in preserving environmental sustainability. However, so many people are less aware of the importance of sustainability and green behavior in business activities. Therefore, the goal of the study is to explore a linkage of green value, GE, and sustainable development that is perceived by entrepreneurship students in Jakarta, Indonesia. 180 students were involved as respondents resulting in significant impacts. By using Smart-PLS proves significant relationships and finds a mediating effect of GE which links

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Zhang, Yi Qing, Wen Jun Cao, and Ai Min Liu. "Analysis of Temperature Characteristics of an AlGaAs/GaAs/Ge Triple-Junction Solar Cell by IS." Advanced Materials Research 756-759 (September 2013): 101–4. http://dx.doi.org/10.4028/www.scientific.net/amr.756-759.101.

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Composition of an AlGaAs/GaAs/Ge triple-junction solar cell were analyzed using an equivalent circuit. The currentvoltage (IV) characteristics and impedance spectroscopy (IS) of it were measured in the temperature range from 20°C to 180°C. In the high-temperature range (from 140°C to 200°C) the VOCchanges faster than those in the low-temperature range (from 20°C to 80°C).This is because contribution of the VOCfrom the Ge subcell becomes nearly zero in the high temperature. R and C of the bottom subcell keep almost the same in the high temperature.

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Rajković, Emina, Christiane Schwarz, Stefan Bruno Kapsamer, et al. "Evaluation of a Dietary Grape Extract on Oxidative Status, Intestinal Morphology, Plasma Acute-Phase Proteins and Inflammation Parameters of Weaning Piglets at Various Points of Time." Antioxidants 11, no. 8 (2022): 1428. http://dx.doi.org/10.3390/antiox11081428.

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Reports of the underlying mechanisms of dietary grape extract (GE) in overcoming weaning challenges in piglets have been partly inconsistent. Furthermore, evaluations of the effects of GE at weaning in comparison to those of widely used therapeutic antibiotics have been scarce. To explore the mode of action of GE in selected tissues and plasma, we evaluated gut morphology, antioxidant and inflammation indices. Accordingly, 180 weaning piglets were allocated to three treatment groups: negative control (NC), NC and antibiotic treatment for the first 5 days of the trial (positive control, PC), an

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Schuster, Sebastian, Leonie Beyer, Carla Palleis, et al. "Impact of Partial Volume Correction on [18F]GE-180 PET Quantification in Subcortical Brain Regions of Patients with Corticobasal Syndrome." Brain Sciences 12, no. 2 (2022): 204. http://dx.doi.org/10.3390/brainsci12020204.

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Corticobasal syndrome (CBS) is a rare neurodegenerative condition characterized by four-repeat tau aggregation in the cortical and subcortical brain regions and accompanied by severe atrophy. The aim of this study was to evaluate partial volume effect correction (PVEC) in patients with CBS compared to a control cohort imaged with the 18-kDa translocator protein (TSPO) positron emission tomography (PET) tracer [18F]GE-180. Eighteen patients with CBS and 12 age- and sex-matched healthy controls underwent [18F]GE-180 PET. The cortical and subcortical regions were delineated by deep nuclei parcell

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Theodoro, D. "Ultrasound Image Quality in the Emergency Department: Sonosite 180 Plus versus GE 400." Academic Emergency Medicine 10, no. 5 (2003): 573. http://dx.doi.org/10.1197/aemj.10.5.573.

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Sangamesh, Rajole, Hiremath Shivashankar, K. S. Ravishankar, and S. M. Kulkarni. "Study on Ballistic Characteristics of Glass-Epoxy-Rubber Sandwiches." Materials Science Forum 978 (February 2020): 245–49. http://dx.doi.org/10.4028/www.scientific.net/msf.978.245.

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This article focuses on the Finite Element (FE) analysis of the ballistic performance of the polymer composites consisting of natural rubber (NR), glass-epoxy (GE) and glass-rubber-epoxy (GRE) sandwich of different thicknesses (3, 6 and 9 mm) under the impact of the conical nose projectile for a velocity variation of (180, 220 and 260 m / s). FE modeling was carried out in direction to forecast the energy absorption, ballistic limit velocity and failure damage mode of the target materail. The significant influence of thickness, interlayer and sandwiching effect was studied: the lowest ballisti

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Geng, Haibin, Jian Luo, Jinglong Li, Jianjun Gao, and Xin Lin. "Thermal Boundary Evolution of Molten Pool During Wire and Arc Additive Manufacturing of Single Walls of 5A06 Aluminum Alloy." Metals 10, no. 7 (2020): 848. http://dx.doi.org/10.3390/met10070848.

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Molten pool uniformity is a prerequisite for wire and arc additive manufacture to achieve a uniform surface appearance. The thermal boundary is a key indicator to evaluate the thermodynamic state of the molten pool. This paper focuses on thermal analysis through finite element simulation and characterizes the thermal evolution of a molten pool during bottom-up deposition. The peak temperature of the substrate plate increases from 375.7 °C to 623.1 °C when peak current increases from 120 A to 180 A. The temperature gradient decreases from 40 °C/mm to 30 °C/mm. Weld speed increases from 0.15 m/m

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Quach, Stefanie, Adrien Holzgreve, Lena Kaiser, et al. "NIMG-26. UPTAKE OF [18F]GE-180 IN TSPO PET IS ASSOCIATED WITH SURVIVAL IN PATIENTS WITH RECURRENT GLIOMA." Neuro-Oncology 24, Supplement_7 (2022): vii167—vii168. http://dx.doi.org/10.1093/neuonc/noac209.644.

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Abstract OBJECTIVE The 18 kDa translocator protein (TSPO) is expressed in both activated microglia and glioma cells. Elevated expression of TSPO has been reported to be associated with higher WHO grade. Here we analyze whether TSPO positron emission tomography (PET) signal using the tracer [18F]GE-180 is correlated with clinical outcome in a cohort of patients with recurrent glioma. METHODS Patients with suspected glioma recurrence received a [18F]GE-180 TSPO PET. All recurrent tumors were confirmed either by stereotactic biopsy or resection. Maximum standard uptake value SUVmax as well as tum

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Veltro, Franco. "La "mitodologia" della Legge 180 e la necessità di una rivoluzione culturale." PSICOTERAPIA E SCIENZE UMANE, no. 2 (May 2023): 285–304. http://dx.doi.org/10.3280/pu2023-002006.

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Il libro di Cavicchi Oltre la 180, centrato su apologia e aporie della Legge 180/1978, ha favorito un grande dibattito con proposte di "ritorno a Basaglia" o di cambiamenti guidati dall'Evidence-Based Medicine (EBM) per modificare l'attuale quadro assistenziale ritenuto insoddisfacente. L'apologia riguarda in realtà le prassi del movimento "post-riforma", divenuto establishment isti-tuzionale, pregiudizievole a ogni confronto e contaminazione con la valutazione quantitativa e con la EBM, artefice di una "mitodologia" della 180. La 180 ha avuto necessità di diversi atti succes-sivi per la sua a

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Бутина, Е. А., Д. Д. Жданов та О. С. Воронцова. "АНАЛИЗ ФАКТОРОВ, ИНТЕНСИФИЦИРУЮЩИХ ОБРАЗОВАНИЕ ГЛИЦИДИЛОВЫХ ЭФИРОВ В ПОДСОЛНЕЧНЫХ МАСЛАХ". Известия вузов. Пищевая технология, № 5-6(398) (23 грудня 2024): 128–34. https://doi.org/10.26297/0579-3009.2024.5-6.20.

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Актуальность исследования образования и накопления глицидиловых эфиров (ГЭ) в подсолнечных маслах обусловлена введением с 1 января 2025 года норматива по содержанию ГЭ в растительных маслах, как производимых масложировыми предприятиями РФ, так и ввозимых на территорию нашей страны. Несмотря на многочисленные исследования, образование ГЭ остается многофакторной проблемой, требующей дальнейшего изучения. Цель настоящего исследования – анализ факторов, влияющих на интенсивность образования и накопле- ния ГЭ в подсолнечных маслах. Задачи исследования включали: изучение влияния наиболее вероятных п

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Petrini, Stefano, Cecilia Righi, Carmen Iscaro, et al. "Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves." Vaccines 8, no. 1 (2020): 14. http://dx.doi.org/10.3390/vaccines8010014.

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Different types of vaccines against Infectious Bovine Rhinotracheitis (IBR) are commercially available. Among these, inactivated glycoprotein E (gE)-deleted marker vaccines are commonly used, but their ability to induce passive immunity is poorly known. Here, we evaluated the passive immunity transferred from dams immunised with commercial inactivated gE-deleted marker vaccines to calves. We vaccinated 12 pregnant cattle devoid of neutralising antibodies against Bovine alphaherpesvirus 1 (BoHV-1) and divided them into two groups with 6 animals each. Both groups were injected with a different i

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Unterrainer, Marcus, Daniel F. Fleischmann, Simon Lindner, et al. "Detection of Cerebrospinal Fluid Dissemination of Recurrent Glioblastoma Using TSPO-PET With 18F-GE-180." Clinical Nuclear Medicine 43, no. 7 (2018): 518–19. http://dx.doi.org/10.1097/rlu.0000000000002113.

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Noge, Hiroshi, Akira Okada, Ta-Ko Chuang, J. Greg Couillard, and Michio Kondo. "Rapid Epitaxial Growth of Si and SiGe Mono-Crystalline Films on Silicon-on-Glass Substrates by Reactive CVD Using SiH4, GeH4, and F2." MRS Proceedings 1426 (2012): 331–37. http://dx.doi.org/10.1557/opl.2012.867.

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ABSTRACTWe have succeeded in the rapid epitaxial growth of Si, Ge, and SiGe films on Si substrates below 670 ºC by reactive CVD utilizing the spontaneous exothermic reaction between SiH4, GeH4, and F2. Mono-crystalline SiGe epitaxial films with Ge composition ranging from 0.1 to 1.0 have been successfully grown by reactive CVD for the first time.This technique has also been successfully applied to the growth of these films on silicon-on-glass substrates by a 20 - 50 ºC increase of the heating temperature. Over 10 μm thick epitaxial films at 3 nm/s growth rate are obtained. The etch pit density

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Filippi, Luca, Viviana Frantellizzi, Giuseppe De Vincentis, Orazio Schillaci, and Laura Evangelista. "Clinical Applications of TSPO PET for Glioma Imaging: Current Evidence and Future Perspective—A Systematic Review." Diagnostics 13, no. 10 (2023): 1813. http://dx.doi.org/10.3390/diagnostics13101813.

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Our aim was to provide a comprehensive overview of the existing literature concerning the clinical applications of positron emission computed tomography (PET) with radiopharmaceuticals targeting the translocator protein (TSPO) in gliomas. A literature search for studies about TSPO PET in the last 10 years (from 2013 to February 2023) was carried out on PubMed, Scopus, and Web of Science using the following keywords: “PET” AND “Gliomas” AND “TSPO”. The Critical Appraisal Skills Program checklist for diagnostic test studies was used for testing the quality of selected papers. Ten articles were s

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Wolf, W., C. A. Presant, V. Waluch, and H. Kim. "Monitoring effects of imatinib (Ima) plus gemcitabine (Ge) chemotherapy (CT) on functional status of tumors (T) using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and magnetic resonance spectroscopy (MRS)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 13001. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.13001.

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13001 Background: The ability to monitor the effect of all interventions on the functional status of tumors is critical in allowing clinicians to optimize/individualize chemotherapy to a given patient (pt). This is especially true when such pts are treated with a combination of targeting agents and cytotoxic anticancer drugs. The present study tested the combination of Ima and Gem to determine T pharmacokinetics (PK) and pharmacodynamics (PD) using DCE-MRI and 19F-MRS. Methods: Pts with measurable and MRI-imagible refractory solid T possibly responsive to Ge were randomized to receive either:

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Rajković, Emina, Christiane Schwarz, David Tischler, et al. "Potential of Grape Extract in Comparison with Therapeutic Dosage of Antibiotics in Weaning Piglets: Effects on Performance, Digestibility and Microbial Metabolites of the Ileum and Colon." Animals 11, no. 10 (2021): 2771. http://dx.doi.org/10.3390/ani11102771.

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Enteric diseases in piglets, such as post-weaning diarrhea (PWD), often require antibiotic treatment of the entire litter. Grape polyphenols may help overcome PWD and thereby reduce the need for antibiotics. The potential of a grape extract (GE; continuous in-feed supplementation) on performance of weaning piglets, compared with both negative (NC; corn-based diet) and positive control (PC; NC + in-feed antibiotic (amoxicillin) in a therapeutic dosage for day 1–day 5 post weaning) was assessed. Apparent total tract digestibility (ATTD) and microbial metabolites were also evaluated on two sampli

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Vettermann, Franziska J., Marcus Unterrainer, Viktoria Ruf, et al. "Dual PET Imaging of an H3K27M-Mutant Glioma With 18F-GE-180 and 18F-FET PET." Clinical Nuclear Medicine 45, no. 12 (2020): 992–93. http://dx.doi.org/10.1097/rlu.0000000000003331.

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Hwang, Ing-Shouh, та Jene A. Golovchenko. "Phase transition of monolayer Pb/Ge(111): β-√3 × √3 R30°⇆1×1 at ∼180 °C". Physical Review B 50, № 24 (1994): 18535–42. http://dx.doi.org/10.1103/physrevb.50.18535.

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Wadsworth, Harry, Paul A. Jones, Wai-Fung Chau, et al. "[18F]GE-180: A novel fluorine-18 labelled PET tracer for imaging Translocator protein 18kDa (TSPO)." Bioorganic & Medicinal Chemistry Letters 22, no. 3 (2012): 1308–13. http://dx.doi.org/10.1016/j.bmcl.2011.12.084.

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Bülbül, Mehmet, Reji Babygirija, Diana Cerjak, Sazu Yoshimoto, Kirk Ludwig, and Toku Takahashi. "Impaired adaptation of gastrointestinal motility following chronic stress in maternally separated rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 302, no. 7 (2012): G702—G711. http://dx.doi.org/10.1152/ajpgi.00447.2011.

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Exposure to early life stress causes increased stress responsiveness and permanent changes in the central nervous system. We recently showed that delayed gastric emptying (GE) and accelerated colonic transit (CT) in response to acute restraint stress (ARS) were completely restored following chronic homotypic stress (CHS) in rats via upregulation of hypothalamic oxytocin (OXT) expression. However, it is unknown whether early life stress affects hypothalamic OXT circuits and gastrointestinal motor function. Neonatal rats were subjected to maternal separation (MS) for 180 min/day for 2 wk. Anxiet

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Jia, Chenhao, Tingting Cui, Qing Ling, et al. "How Small Can S-boxes Be?" IACR Transactions on Symmetric Cryptology 2025, no. 1 (2025): 592–622. https://doi.org/10.46586/tosc.v2025.i1.592-622.

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S-boxes are the most popular nonlinear building blocks used in symmetrickey primitives. Both cryptographic properties and implementation cost of an S-box are crucial for a good cipher design, especially for lightweight ones. This paper aims to determine the exact minimum area of optimal 4-bit S-boxes (whose differential uniform and linearity are both 4) under certain standard cell library. Firstly, we evaluate the upper and lower bounds upon the minimum area of S-boxes, by proposing a Prim-like greedy algorithm and utilizing properties of balanced Boolean functions to construct bijective S-box

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Müller, Luisa, Nicole Power Guerra, Anna Schildt, et al. "[18F]GE-180-PET and Post Mortem Marker Characteristics of Long-Term High-Fat-Diet-Induced Chronic Neuroinflammation in Mice." Biomolecules 13, no. 5 (2023): 769. http://dx.doi.org/10.3390/biom13050769.

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Obesity is characterized by immoderate fat accumulation leading to an elevated risk of neurodegenerative disorders, along with a host of metabolic disturbances. Chronic neuroinflammation is a main factor linking obesity and the propensity for neurodegenerative disorders. To determine the cerebrometabolic effects of diet-induced obesity (DIO) in female mice fed a long-term (24 weeks) high-fat diet (HFD, 60% fat) compared to a group on a control diet (CD, 20% fat), we used in vivo PET imaging with the radiotracer [18F]FDG as a marker for brain glucose metabolism. In addition, we determined the e

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Feeney, Claire, Gregory Scott, Joel Raffel, et al. "Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain." European Journal of Nuclear Medicine and Molecular Imaging 43, no. 12 (2016): 2201–10. http://dx.doi.org/10.1007/s00259-016-3444-z.

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Unterrainer, Marcus, C. Mahler, L. Vomacka, et al. "TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing–remitting multiple sclerosis." European Journal of Nuclear Medicine and Molecular Imaging 45, no. 8 (2018): 1423–31. http://dx.doi.org/10.1007/s00259-018-3974-7.

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Safa Cinarli, Fahri, Emin Kafkas, Kalema Rudy, Tulay Yildirim, Isaac Selva Raj, and Steven Duhig. "Relationship between Rectus Femoris Muscle Architecture and Isokinetic Peak Knee Extension Torque in Physically Active Men." Sport Mont 22, no. 2 (2024): 19–24. http://dx.doi.org/10.26773/smj.240703.

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The aim of this study was to examine the relationship between rectus femoris muscle architecture and isokinetic concentric peak knee extension torque at various velocities. Twenty physically active men (age =21.1±1.41 years, weight =69.9±5.7 kg, height =176.4±7.07 cm) had their isokinetic concentric knee extensor (Biodex 4 Pro, Biodex Medical Inc, Shirley, USA) strength assessed at 60°/sec, 180°/sec and 300°/sec. Pennation angle, muscle thickness, and fascicle length of the rectus femoris was measured using real-time B-mode ultrasound (Logiq P5, GE Healthcare, UK). Pennation angle had a signif

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Wu, Yifei, Zuoru Dong, Yulu Chen, et al. "Optimization of Pixel Size and Electrode Structure for Ge:Ga Terahertz Photoconductive Detectors." Sensors 22, no. 5 (2022): 1916. http://dx.doi.org/10.3390/s22051916.

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To investigate the effects of the pixel sizes and the electrode structures on the performance of Ge-based terahertz (THz) photoconductive detectors, vertical structure Ge:Ga detectors with different structure parameters were fabricated. The characteristics of the detectors were investigated at 4.2 K, including the spectral response, blackbody response (Rbb), dark current density-voltage characters, and noise equivalent power (NEP). The detector with the pixel radius of 400 μm and the top electrode of the ring structure showed the best performance. The spectral response band of this detector wa

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Mastari, Marouane, Matthew Charles, Patricia Pimenta-Barros, et al. "Ge Nano-Heteroepitaxy: From Nano-Pillars to Thick Coalesced Layers." ECS Meeting Abstracts MA2022-02, no. 32 (2022): 1229. http://dx.doi.org/10.1149/ma2022-02321229mtgabs.

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Ge co-integration with Si has always attracted a lot of attention. Thanks to its superior electronic properties, Ge can be used as a channel material in p-type Metal Oxide Semiconductor transistors (high hole mobility) or low power devices such as tunnelling field effect transistors (steep sub-threshold swing operation). Furthermore, Ge is a key enabler in numerous optoelectronic devices (light emitters and photo-detectors). The epitaxial growth of Ge on Si is far from being lattice matched, with a 4.2% difference between Si and Ge, making high quality growth difficult, especially for thick la

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Bjerregaard, J. K., K. R. Schønnemann, H. A. Jensen, L. W. Vestermark, T. P. Hansen, and P. Pfeiffer. "Biweekly cetuximab and irinotecan as second-line therapy to patients with platinium-resistant gastroesophageal cancer." Journal of Clinical Oncology 27, no. 15_suppl (2009): e15624-e15624. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e15624.

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e15624 Background: There is no established 2nd line therapy for patients (pts) with advanced gastroesophageal (GE) cancer. In 2004, the Danish government initiated a national health programme for pts with advanced cancer. Non- proven therapy may be offered after approval by an expert panel appointed by the National Board of Health that subsequently finances the cost of treatment. This programme has had a major impact on the management of cancer pts in Denmark and has accelerated the introduction and implementation of new therapies. Inspired by the excellent results in colorectal cancer a combi

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Williams, Lacey Scott, Anne S. S. Renteria, Maher Albitar, and Gustavo A. Rivero. "Immune and Myeloid Differentiation Shape Transcriptome to Discriminate Evolutionary Stages of Cellular Transformation." Blood 144, Supplement 1 (2024): 2923. https://doi.org/10.1182/blood-2024-211159.

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Background: Myeloid mutations retain ability to elicit variable innate immunity response. T-cell “autoimmunity” restricts myeloid clonal expansion suggesting that “clonal evolution” requires genomic and transcriptomic modifications to “enhance cellular fitness”. Gene expression (GE) could assist exome sequencing in monitoring clonal evolution and to understand how transformed myeloid cells behave under immune selective pressure. In this study, our aims are: (a) to describe transcriptomic immune and inflammatory modifications in patients (pt) harboring clonal hematopoiesis (CH), myelodysplastic

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