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Journal articles on the topic 'GEA Group'

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Published: 4 June 2021
Last updated: 15 February 2022

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1

Hüllmann, Ulrich, and Andreas Hoffjan. "Controlling in der GEA Group." Controlling 21, no. 7 (2009): 409–11. http://dx.doi.org/10.15358/0935-0381-2009-7-409.

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2

Schlienkamp, Christoph. "GEA Group AG — Konzernabschluss zum 31.12.2018." Die Aktiengesellschaft 64, no. 23 (December 1, 2019): r346—r347. http://dx.doi.org/10.9785/ag-2019-642324.

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3

Hüllmann, Ulrich. "Controlling bei der GEA Group AG." Controlling 19, no. 10 (2007): 561–68. http://dx.doi.org/10.15358/0935-0381-2007-10-561.

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4

Michael, Ian, Melodena Stephens Balakrishnan, and Zeenath Khan. "GEA Group – doing business in the Middle East." Emerald Emerging Markets Case Studies 5, no. 3 (June 22, 2015): 1–14. http://dx.doi.org/10.1108/eemcs-03-2015-0038.

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Subject area Management, Strategy, International business. Study level/applicability Undergraduate or Graduates. Case overview This case is suitable for students of international business and strategy at the advanced undergraduate-level or introductory masters-level courses. It can be used for organizational design, brand management and business-to-business management classes. It may be of interest to practitioners in the Middle East and North African (MENA) markets looking at managing cross-functional teams. Expected learning outcomes On completion of utilizing the case study as an exercise, students should be able to develop the following. Case-specific skills: Critically examine the importance of the international business and strategy in the Middle East and demonstrate this by analyzing real-regional/-examples using complex theoretical frameworks; identify examples of best practice and explain the dynamics toward international business and strategy with reference to a range of theoretical models and apply these in a meaningful way to the MENA region. Discipline-specific skills: Synthesize and critically evaluate a corpus of academic literature and government reports on international business and strategy; link international business and strategy concepts and theories to real-regional/world examples. Personal and key skills: Reflect on the process of learning and undertake independent/self-directed learning (including time management) to achieve consistent, proficient and sustained attainment; work as a participant or leader of a group and contribute effectively to the achievement of objectives in the field of international business and strategy. Supplementary materials Teaching notes are available for educators only. Please contact your library to gain login details or email support@emeraldinsight.com to request teaching notes.
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5

Terada, Takuro, Shigeyuki Tomita, Yoshihide Asaumi, Yoshinao Koshida, Nobuki Ishikawa, and Go Watanabe. "Effects of Ultrasonic Skeletonization of the Gastroepiploic Artery on Endothelial Nitric Oxide Production." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 4, no. 2 (March 2009): 93–98. http://dx.doi.org/10.1097/imi.0b013e3181a347cc.

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Objective The right gastroepiploic artery (GEA) is a reliable conduit for coronary artery bypass grafting. Recently, ultrasonic skeletonization in graft harvesting has attracted attention as an alternative technique to increase the length and caliber size of grafts. The influence of GEA skeletonization using an ultrasonically activated device with that using an electrosurgical unit was compared from the viewpoint of production of nitric oxide (NO). Methods Fourteen pigs were used in this study. The GEA were harvested using an ultrasonically activated device (group ultrasonically activated device [USAD], n = 7) or electrocautery (group E, n = 7). Blood sampling was performed at the following three times from the distal end of the GEA: (1) preskeletonization, (2) pedicle, and (3) postskeletonization. Plasma NOx (NO metabolites) levels were measured by chemiluminescent assay. Moreover, in excised specimens, the expression of nitric oxide synthase was examined immunohistologically. Results In group USAD, the preskeletonization basal level of plasmaNOx in GEA was 25.7 ± 10.9 μmol/L, which then increased to 26.9 ± 10.5 μmol/L (pedicle) and 32.2 ± 12.1 μmol/L (postskeletonization). In group E, the preskeletonization basal plasma NOx level in GEA was 28.9 ± 11.4 μmol/L, which changed to 27.5 ± 8.9 μmol/L (pedicle) and 21.8 ± 8.3 μmol/L (postskeletonization). The results of multivariate analysis indicated that the patterns of changes in plasma NOx level were significantly different in both groups (P = 0.024). In group USAD, post hoc multiple comparison tests revealed a significant difference between preskeletonization and postskeletonization (P = 0.037). Conclusions Ultrasonically skeletonized GEA showed increased effective graft length, higher free flow capacity, and increased endothelial NO production than that prepared using an electrosurgical unit.
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Whittaker, William E., and Glenn R. Storey. "Ground-penetrating radar survey of the Sny Magill Mound Group, Effigy Mounds National Monument, Iowa." Geoarchaeology 23, no. 4 (June 16, 2008): 474–99. http://dx.doi.org/10.1002/gea.20229.

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Aru, Angeolo, Salvatore Carboni, Maria-Raimonda Usai, and Andrea Vacca. "Summary of the workshop of the Archaeological Soil Micromorphology Working Group, Sardinia, Italy, April 11-14, 2002." Geoarchaeology 18, no. 7 (September 11, 2003): 827–29. http://dx.doi.org/10.1002/gea.10092.

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Dickinson, William R., David V. Burley, and Richard Shutler. "Impact of hydro-isostatic holocene sea-level change on the geologic context of Island archaeological sites, Northern Ha'apai group, Kingdom of Tonga." Geoarchaeology 9, no. 2 (April 1994): 85–111. http://dx.doi.org/10.1002/gea.3340090202.

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9

Peruzzi, Pierpaolo, Sergio D. Bergese, Adolfo Viloria, Erika G. Puente, Mahmoud Abdel-Rasoul, and E. Antonio Chiocca. "A retrospective cohort-matched comparison of conscious sedation versus general anesthesia for supratentorial glioma resection." Journal of Neurosurgery 114, no. 3 (March 2011): 633–39. http://dx.doi.org/10.3171/2010.5.jns1041.

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Object Glioma resection under conscious (“awake”) sedation (CS) is used for eloquent areas of the brain to minimize postoperative neurological deficits. The objective of this study was to compare the duration of hospital stay, overall hospital cost, perioperative morbidity, and postoperative patient functional status in patients whose gliomas were resected using CS versus general endotracheal anesthesia (GEA). Methods Twenty-two cases in 20 patients who underwent surgery for cerebral gliomas under CS and a matched cohort of 22 cases in 19 patients who underwent surgery under GEA over a 3-year period were retrospectively evaluated. Criteria for inclusion in the study were as follows: 1) a single cerebral lesion; 2) gross-total resection as evidenced by postoperative Gd-enhanced MR imaging within 48 hours of surgery; 3) a WHO Grade II, III, or IV glioma; 4) a supratentorial lesion location; 5) a Karnofsky Performance Scale score ≥ 70; 6) an operation performed by the same neurosurgeon; and 7) an elective procedure. Results The average hospital stay was significantly different between the 2 groups: 3.5 days for patients who underwent CS and 4.6 days for those who underwent GEA. This result translated into a significant decrease in the average inpatient cost after intensive care unit (ICU) care for the CS group compared with the GEA group. Other variables were not significantly different. Conclusions Patients undergoing glioma resection using CS techniques have a significantly shorter hospital stay with reduced inpatient hospital expenses after postoperative ICU care.
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Słysz, Aleksander. "In dubio pro tributario – discrimination of a group of taxpayers. Does the current shape of the norms violate the principle of equality before the law?" Gubernaculum et Administratio 2(18) (2018): 83–99. http://dx.doi.org/10.16926/gea.2018.02.14.

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11

Watanabe, Go, Shojiro Yamaguchi, Shigeyuki Tomita, and Yuji Nishida. "Fasudil is an Effective Graft Vasodilator for Gastroepiploic Artery in Coronary Artery Bypass Grafting." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 10, no. 4 (July 2015): 268–72. http://dx.doi.org/10.1097/imi.0000000000000178.

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Objective The gastroepiploic artery (GEA) has been used as an alternative arterial in situ graft for coronary artery bypass grafting (CABG). However, because of the large individual differences and the spastic nature of the GEA, caution has to be exercised during harvesting. We evaluated the usefulness of fasudil, a Rho kinase inhibitor, as a vasodilator for right GEA (RGEA) graft after harvesting, compared with the conventional agents papaverine and verapamil-nitroglycerin. Methods Between June 2009 and January 2013, 30 patients with ischemic heart disease who underwent isolated CABG using RGEA graft were randomly assigned to fasudil (n = 10), papaverine (n = 10), or verapamil-nitroglycerin (n = 10) group. Fasudil (2.67 mmol/L), papaverine (1.0 mmol/L) mixed with heparinized blood, or verapamil-nitroglycerin (30 μmol/L each) was injected intraluminally into the RGEA graft after harvesting. Right GEA graft free flow (GFF), hemodynamic changes, and histopathology of RGEA were evaluated. Results Intraluminal injection of fasudil increased GFF significantly (P < 0.001) and markedly from 41.5 ± 31.5 mL/min at baseline to 149.3 ± 46.7 mL/min after injection. Papaverine increased GFF (P < 0.001) from 40.0 ± 35.8 to 64.9 ± 33.7 mL/min, and verapamil-nitroglycerin also increased GFF (P < 0.001) from 38.8 ± 32.1 to 79.0 ± 35.2 mL/min. The GFF was significantly higher (P = 0.001) in the fasudil group than in the other two groups. Histopathologically, fasudil treatment markedly increased the diameter of RGEA graft, while maintaining integrity of the multiple elastic lamellae. Blood pressure did not change significantly after drug injection in all groups. Conclusions Fasudil is more potent than papaverine or verapamilnitroglycerin in increasing GFF of RGEA graft for CABG.
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O'Brien, Christopher J. "Fossil elephantoids from the hominid-bearing awash group, middle awash valley, afar depression, Ethiopia. Jon E. Kalb and Assefa Mebrate, 1993, Transactions of the American Philosophical Society, Volume 83, Part 1, 114 pp., $15.00 (paperbound)." Geoarchaeology 11, no. 1 (January 1996): 83–84. http://dx.doi.org/10.1002/gea.3340110105.

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13

Wood, Anthony, Yonghong Zhang, Qianxing Mo, Ling Cen, Jacques Fontaine, Sarah E. Hoffe, Jessica M. Frakes, et al. "Comprehensive evaluation of genomic alterations in patients with gastric and gastroesophageal adenocarcinoma stratified according to TP53 mutation status." Journal of Clinical Oncology 39, no. 3_suppl (January 20, 2021): 238. http://dx.doi.org/10.1200/jco.2021.39.3_suppl.238.

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238 Background: Gastric (GC) and gastroesophageal adenocarcinomas (GEA) are molecularly diverse. Molecular biomarkers of clinical significance have been identified that impact treatment decision making. TP53 is the most frequently altered gene with approximately 50% of patients harboring mutations. However, TP53 mutations have not yet been confirmed as a target of therapeutic benefit. This study aimed to identify distinct genomic alterations that are dominant in TP53 mutated (MUT) versus wild-type (WT) GC and GEA in order to elucidate alternative therapeutic targets within these subsets. Methods: De-identified data for 3741 patients with GC and GEA was obtained from Foundation Medicine. The data obtained were age, gender, tumor mutational burden (TMB), and the distinct genomic alterations noted on DNA sequencing. The dataset was sorted by TP53 mutation status. Differences in mutation frequency were detected using the Fisher’s exact test of independence with a p-value of < 0.01 designated as the cutoff value for statistical significance. Results: The dataset consisted of 2946 GCs and 795 GEAs. TP53 mutations were present in 65.8% of specimens. 61.6% of GCs and 81.4% of GEAs were TP53 MUT positive (p = < .001). Median TMB score and the frequency of tumors with a TMB score > 10 was similar in both TP53 MUT and WT groups. 49 genes had statistically different mutation frequencies in TP53 MUT vs. WT patients. Top co-occurring genetic alterations in TP53 MUT patients included amplification and point mutations in MYC, CCNE1, MET, ERBB2, and EGFR. Amplification and point mutations in MDM2, CDK4, ARID1A, PIK3CA, and ERBB3 were the top co-occurring genetic alterations in TP53 WT patients. Conclusions: There was a high frequency of TP53 mutations in this group of GC and GEA patients, with a higher incidence of TP53 mutations identified in GEA samples. The mutational profiles of these tumors differed according to TP53 mutation status. These differences may be able to serve as the foundation for future clinical investigations.
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Trlin, Davor. "Economic and Social Rights Lost in Transition." Gubernaculum et Administratio 2(22) (2020): 63–73. http://dx.doi.org/10.16926/gea.2020.02.11.

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All European constitutions after World War II expressed their commitment to economic and social rights. Those countries that began building socialist social order after the war specially emphasized those rights. After the break-up of the “socialist paradigm” and the establishment of “new democracies”, constitutional leaders have taken a new stance towards the socio-economic group. This is the process that did not bypassed countries formed by dissolution of Yugoslavia. We will analyse specially what is left of the constitutional experiment of self-management. Nowadays, there is no workers’ participation in place in any of the countries that emerged after the breakup of the former Yugoslavia, neither as a system nor as a practice of having consultations within companies with the aim to address specific technological, organisational and social problems. There are several reasons for this, but the basic reason is that politicians still believe that workers’ participation was created as part of the ideological apparatus of the former socialist system. By way of property rights and small shareholding, the laws opened the way to participation, and the legal framework could continue to develop.
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Zsótér, Brigitta, and Bálint Kura. "Economic Calculations of an Investment of a Slicing and Packaging Production Line." Analecta Technica Szegedinensia 11, no. 1 (January 3, 2017): 23–31. http://dx.doi.org/10.14232/analecta.2017.1.23-31.

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We test a Csongrád county meat-packing factory’s new slicing-packing production line’s investment. We value the different tenders from five main viewpoints, these are the following: the NPV (Net Present Value), IRR (Internal Rate of Return), DPB (Dynamic Payback), PI (Profitability Index), PB (Payback Time). During the calculation, we have experienced that both tenders would be viable financially. We recommended the offer of the GEA Group AG.
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Castellví Mata, Jordi. "Read the world to write the future: An interview with professors E Wayne Ross and Xosé Manuel Souto, experts in critical social studies." Bellaterra Journal of Teaching & Learning Language & Literature 14, no. 2 (July 20, 2021): e974. http://dx.doi.org/10.5565/rev/jtl3.974.

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E Wayne Ross is professor at the University of British Columbia (Canada). He is interested in the influence of social and institutional contexts on teachers’ practice as well as the role of curriculum and teaching in building a democratic society in the face of antidemocratic impulses of greed, individualism, and intolerance. Xosé Manuel Souto is professor at the University of Valencia (Spain), in the department of social and experimental sciences education. He directs the Gea-Clío educational innovation group that has developed, for the past thirty years, its work in the fields of teacher training, creation of curricular material and educational research.
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Joshi, Smita Suhas, Steven Brad Maron, S. Lomnicki, Blase N. Polite, Manish Sharma, Jennifer Ibe, Kenisha Allen, et al. "Personalized antibodies for gastroesophageal adenocarcinoma (PANGEA): A phase II precision medicine trial (NCT02213289)." Journal of Clinical Oncology 36, no. 4_suppl (February 1, 2018): TPS198. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.tps198.

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TPS198 Background: Targeted therapies (tx) in GEA have had limited efficacy despite recognition of numerous ‘targetable’ molecular events. This may be due to the molecular heterogeneity (MH) that exists between patients (pts), within the primary tumor (PT), between PT and synchronous metastatic lesions (MLs), and in lesions over time. Current biomarker profiling (BP) is performed on one site, usually the PT, yet this fails to capture the MH of GEA, with likely major clinical implications. Classic trial designs are challenged by MH, low frequency oncogenic drivers, and scarcity of tissue. There is need for novel trial designs and BP technologies that address these concerns, provide tx algorithms for pts with multiple aberrations, and have access to several txs. Methods: This phase IIa, open-label, non-randomized ‘platform trial’ enrolls pts with newly diagnosed metastatic GEA or recurrent disease after curative-intent surgery. Baseline tumor BP is performed on PT/ML along with circulating free (cf)DNA. Pts receive first line (1L) mFOLFOX6 + biologic tx based on BP of the ML using a prioritized tx algorithm (HER2+: trastuzumab; MET+: none; FGFR2+: none; EGFR+: ABT806; MSI-H: nivolumab; ‘RAS-like’: ramucirumab). MET/FGFR2 arms (~10% of all pts) are tx’d with cytotoxics only and followed for natural outcome until/if tx becomes available on study. At first progression (PD1), pts undergo biopsy of growing ML and change to 2L FOLFIRI + biologic agent as assigned in 1L tx. Upon results of PD1 biopsy, pts change to a new biologic tx if the molecular category evolves. At PD2, pts change to 3L FOLTAX + biologic as determined after PD1, and switch biologic tx from PD2 biopsy result. All PD1/PD2 tumor/cfDNA samples undergo BP to assess evolution and resistance mechanisms. Co-primary endpoints: safety, feasibility, and overall survival (OS) of this personalized treatment strategy (excluding MET/FGFR2) compared to historical controls (HR 0.66). Secondary endpoints include rate of baseline MH between PT and ML leading to new treatment assignment; utility of cfDNA; overall progression-free survival (PFS)/response rate (RR); OS/PFS/RR in each targetable group. Since 8/2015, 38 of 68 planned pts have been accrued. Clinical trial information: NCT02213289.
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Lorenzen, Sylvie, Peter C. Thuss-Patience, Claudia Pauligk, Eray Goekkurt, Thomas Jens Ettrich, Florian Lordick, Michael Stahl, et al. "FOLFIRI plus ramucirumab versus paclitaxel plus ramucirumab for patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction as second-line therapy: Interim safety and efficacy results from the phase II RAMIRIS Study (AIO-STO-0415) of the German Gastric Group at AIO." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 4023. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.4023.

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4023 Background: Ramucirumab as monotherapy and in combination with paclitaxel is a proven second-line option for advanced gastroesophageal adenocarcinoma (GEA). More and more patients (pts) are pretreated with docetaxel in the perioperative or first-line setting. For those pts, the benefit of a combination of ramucirumab and paclitaxel is unclear, and physicians would choose an irinotecan-based regimen as second line treatment. This provides a rationale for the evaluation of FOLFIRI + ramucirumab. Methods: This is a multicenter, randomized, investigator initiated, phase II trial, planned to include 111 pts with advanced GEA to receive 2:1 either FOLFIRI plus ramucirumab every two weeks (Arm A) or paclitaxel (days 1, 8, 15 of a 28-day cycle) plus ramucirumab every two weeks (Arm B). Primary endpoint is 6-months OS rate. This abstract displays interim results of safety and overall objective response (ORR) in docetaxel pre-treated group from up to 65 randomized pts. The results were needed to decide on conducting a subsequent phase III study. Results: 58 (A, 36; B, 22) pts were included in the safety analysis and 50 pts with tumor assessment in the response analysis. Main ≥ grade 3 adverse events were respectively in arms A/B: neutropenia (20%/22%), fatigue (6%/0%), diarrhea (8%/3%), and related SAEs (14% v 23%). Twenty-nine of 50 pts (58%) were pre-treated with docetaxel. In these pts, ORR was 30% in Arm A (5/17) and 8% (1/12) in Arm B. Disease control rate (DCR) was 65% and 50% for Arm A and B respectively. Conclusions: The interim safety analysis of the RAMIRIS trial has demonstrated feasibility of the combination of FOLFIRI and ramucirumab. Docetaxel pre-treated pts had higher ORR and DCR when ramucirumab is combined with FOLFIRI, instead of paclitaxel. EudraCT: 2015-005171-24. Clinical trial information: NCT03081143.
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Yarris, Lalena M., Amy Miller Juve, Anthony R. Artino, Gail M. Sullivan, Steven Rougas, Barbara Joyce, and Kevin Eva. "Expertise, Time, Money, Mentoring, and Reward: Systemic Barriers That Limit Education Researcher Productivity—Proceedings From the AAMC GEA Workshop." Journal of Graduate Medical Education 6, no. 3 (September 1, 2014): 430–36. http://dx.doi.org/10.4300/jgme-d-14-00340.1.

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Abstract Background To further evolve in an evidence-based fashion, medical education needs to develop and evaluate new practices for teaching, learning, and assessment. However, educators face barriers in designing, conducting, and publishing education research. Objective To explore the barriers medical educators face in formulating, conducting, and publishing high-quality medical education research, and to identify strategies for overcoming them. Methods A consensus workshop was held November 5, 2013, at the Association of American Medical Colleges annual meeting. A working group of education research experts and educators completed a preconference literature review focusing on barriers to education research. During the workshop, consensus-based and small group techniques were used to refine the broad themes into content categories. Attendees then ranked the most important barriers and strategies for overcoming them with the highest potential impact. Results Barriers participants faced in conducting quality education research included lack of (1) expertise, (2) time, (3) funding, (4) mentorship, and (5) reward. The strategy considered most effective in overcoming these barriers involved building communities of education researchers for collaboration and networking, and advocating for education researchers' interests. Other suggestions included trying to secure increased funding opportunities, developing mentoring programs, and encouraging mechanisms to ensure protected time. Conclusions Barriers to education research productivity clearly exist. Many appear to result from feelings of isolation that may be overcome with systemic efforts to develop and enable communities of practice across institutions. Finally, the theme of “reward” is novel and complex and may have implications for education research productivity.
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Suwanti, Suwanti, Puji Purwaningsih, and Umi Setyoningrum. "Pengaruh Senam Ergonomik Terhadap Tekanan Darah Lansia dengan Hipertensi." Jurnal Penelitian Perawat Profesional 1, no. 1 (November 30, 2019): 1–12. http://dx.doi.org/10.37287/jppp.v1i1.15.

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Hipertensi merupakan penyebab kematian paling umum ketiga setelah stroke dan tuberkulosis. Penanganan yang tepat diperlukan untuk mencegah tidak terkontrolnya tekanan darah dan komplikasinya. Senam ergonomik sebagai terapi non farmakologi memiliki manfaat luas untuk mempertahankan kesehatan umum.Penelitian ini untuk menentukan pengaruh senam ergonomik terhadap terhadap tekanan darah lansia dengan hipertensi diWening Wardoyo Ungaran. Penelitian ini menggunakan pre experiment -one group pre-test post-test design. Sampel sebanyak 15 lansia dengan hipertensi yang diseleksi dengan purposive sampling. Pengambilan data dengan menggunakan lembar observasi dan Sphygmomanimeter air raksa (GEA Medical). Intervensi telah dilakukan sebanyak 3 kali per minggu. Test statistik menggunakan uji Wilcoxon. Hasil uji statistik dengan Wilcoxon menunjukkan p value sistolik=0,000 lebih kecil dari α value (0,05), p value diastolik=0,011 lebih kecil dari α value (0,05). Hasil menunjukkan ada pengaruh yang signifikan senam ergonomik terhadap sistolik dan diastolik lansia. Peneliti menyarankan bahwa senam ergonomik dapat digunakan pada lansia dengan hipertensi sebagai terapi non farmakologi. Kata kunci: lansia, senam ergonomik, hipertensi THE EFFECT OF ERGONOMIC EXERCISE ON BLOOD PRESSURE IN ELDERLY HYPERTENSION IN WENING WARDOYO UNGARAN ABSTRACT Hypertension is the third most common cause of death after stroke and tuberculosis. Proper handling is needed to prevent uncontrolled blood pressure and complications. Ergonomic exercise as non-pharmacological therapy has very broad benefits to maintain general health. This research aim to determine the effect of ergonomic exercise on blood pressure in elderly hypertention in Wening Wardoyo Ungaran. The research used pre experiment -one group pre-test post-test design. A sample of 15 elderly with hypertension was selected by purposive sampling. Data collecting used observation sheet and Sphygmomanometer (GEA medical). The intervention was done for 3 times/week. Statistical test used Wilcoxon.The result of test obtained p value of sistolic=0,000 smaller than α value (0,05), p value of diastolic=0,011 smaller than α value (0,05). The results showed there were significant effect of ergonomic exercise on sistolic and sistolic. Researchers suggest that ergonomic exercise can be used in elderly hipertension as non- pharmacological therapy. Keywords: elderly, ergonomic exercise, hypertension
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Nafi'ah, Nafi'ah, Mu’jizatillah Mu’jizatillah, and Jhudi Bonosari Soediono. "EFEKTIFITAS KOMBINASI GREEN TEA EXTRACT DAN SENOBI BREATHING EXERCISE UNTUK MENURUNKAN PREVALENSI LEMAK TUBUH REMAJA PADA KONDISI AKUT." Jurnal Insan Farmasi Indonesia 3, no. 2 (December 28, 2020): 354–60. http://dx.doi.org/10.36387/jifi.v3i2.587.

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In last decade there has been an increase prevalence of overweight adolescents. Various strategies and products have been evaluated in effort to prevent and treat overweight using Green Tea Extract (GTE) and Senobi Breathing Exercise (SBE). However, the effect of GTE and SBE on decreasing adolescent body fat percentage in acute conditions when combined are unknown. The method used quasi experimental with control group design. The research conducted in Gymnasium laboratory of the Politeknik Unggulan Kalimantan in March 2020. The samples used were aged 18-21 years with BMI 25-29.9. Determination of samples using Federer's formula: (t-1) (n-1) ?15 obtained 4 treatment groups with a sample size of each group are 10 people that divided into: (a) overweight GTE; (b) overweight SBE; (c) overweight GTE and SBE; (d) overweight control . Measurement percentage of body fat in acute conditions shortly after treatment utilize Body Fat Monitor Scale GEA Medical EF 981. Statistical Test using Krusskall Wallis , the results obtained were P> 0.05, which indicates that there was no significant effect of GTE and SBE to reduce prevalence of adolescent body fat in acute conditions. Further research is needed to find out the correct protocol.
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Rodin, Andrei S., Grigoriy Gogoshin, Seth Hilliard, Lei Wang, Colt Egelston, Russell C. Rockne, Joseph Chao, and Peter P. Lee. "Dissecting Response to Cancer Immunotherapy by Applying Bayesian Network Analysis to Flow Cytometry Data." International Journal of Molecular Sciences 22, no. 5 (February 26, 2021): 2316. http://dx.doi.org/10.3390/ijms22052316.

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Cancer immunotherapy, specifically immune checkpoint blockade, has been found to be effective in the treatment of metastatic cancers. However, only a subset of patients achieve clinical responses. Elucidating pretreatment biomarkers predictive of sustained clinical response is a major research priority. Another research priority is evaluating changes in the immune system before and after treatment in responders vs. nonresponders. Our group has been studying immune networks as an accurate reflection of the global immune state. Flow cytometry (FACS, fluorescence-activated cell sorting) data characterizing immune cell panels in peripheral blood mononuclear cells (PBMC) from gastroesophageal adenocarcinoma (GEA) patients were used to analyze changes in immune networks in this setting. Here, we describe a novel computational pipeline to perform secondary analyses of FACS data using systems biology/machine learning techniques and concepts. The pipeline is centered around comparative Bayesian network analyses of immune networks and is capable of detecting strong signals that conventional methods (such as FlowJo manual gating) might miss. Future studies are planned to validate and follow up the immune biomarkers (and combinations/interactions thereof) associated with clinical responses identified with this computational pipeline.
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López-Bautista, Fabiola, Rosalinda Posadas-Sánchez, Christian Vázquez-Vázquez, José Manuel Fragoso, José Manuel Rodríguez-Pérez, and Gilberto Vargas-Alarcón. "IL-37 Gene and Cholesterol Metabolism: Association of Polymorphisms with the Presence of Hypercholesterolemia and Cardiovascular Risk Factors. The GEA Mexican Study." Biomolecules 10, no. 10 (October 5, 2020): 1409. http://dx.doi.org/10.3390/biom10101409.

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Interleukin 37 (IL-37) is an anti-inflammatory cytokine involved in the regulation of cholesterol homeostasis, reducing the levels of plasma cholesterol, fatty acids, and triglycerides. The aim of the present study was to evaluate the association of the IL-37 polymorphisms with the presence of hypercholesterolemia (HC), and with cardiovascular risk factors. Nine IL-37 polymorphisms (rs2708965, rs2708962, rs6717710, rs2708961, rs2708960, rs2708958, rs2723187, rs2708947, and rs2723192) were determined by TaqMan assays in a group of 1292 individuals (514 with and 778 without hypercholesterolemia) belonging to the cohort of the GEA Mexican Study. The associations were evaluated by logistic regression, using inheritance models adjusted by confounding variables. Under codominant 1 model, the rs2708961 (OR = 0.51, p = 0.02), rs2723187 (OR = 0.35, p = 0.005), and rs2708947 (OR = 0.49, p = 0.02) polymorphisms were associated with low risk of HC. The association of the polymorphisms with cardiovascular risk factors was evaluated independently in HC and non-HC individuals. In non-HC individuals, some polymorphisms were associated with the risk of having high levels of LDL-C, glucose, and high risk of T2DM, and low risk of having high visceral abdominal fat. On the other hand, in individuals with HC five, polymorphisms were associated with high levels of C-reactive protein. The IL-37 rs2708961, rs2723187, rs2708947 polymorphisms were associated with low risk of HC, and some IL-37 polymorphisms were associated with cardiometabolic factors in both individuals with and without HC.
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24

Branyon, D. P., J. A. Caton, and K. Annamalai. "Coal-Fueled Diesel Cycle Simulation: The Role of Group Effects." Journal of Engineering for Gas Turbines and Power 112, no. 3 (July 1, 1990): 391–97. http://dx.doi.org/10.1115/1.2906507.

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An existing coal-water slurry fueled diesel engine cycle simulation was modified to include particle-to-particle and droplet-to-droplet interactions during the combustion and vaporization processes. Two aspects of these interactions, known as group effects, were considered. Group Effect Number 1 (GE1) relates to the species concentrations and temperature profiles between particles during combustion and between droplets during vaporization. Group Effect Number 2 (GE2) relates to the blockage of air entrainment to the fuel region due to the large momentum flux of volatiles and CO during combustion or water vapor during vaporization. The major conclusions were that GE1 affected the detailed process characteristics and in-cylinder conditions, and moderately affected the overall engine performance for the cases studied. These results were largely due to suppression of the water vaporization process relative to the case with no group effects. GE2 did not significantly affect the in-cylinder processes or the overall performance of the engine for the cases studied.
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25

Posadas-Sánchez, Rosalinda, Nonanzit Pérez-Hernández, Javier Angeles-Martínez, Fabiola López-Bautista, Teresa Villarreal-Molina, José Manuel Rodríguez-Pérez, José Manuel Fragoso, Carlos Posadas-Romero, and Gilberto Vargas-Alarcón. "Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study." Mediators of Inflammation 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/6012795.

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Interleukin 35 (IL-35) is a heterodimeric cytokine involved in the development of atherosclerosis. The aim of the present study was to establish if the polymorphisms ofIL-12AandEBI3genes that encode the IL-35 subunits are associated with the development of premature coronary artery disease (CAD) in Mexican individuals. TheIL-12AandEBI3polymorphisms were determined in 1162 patients with premature CAD and 873 controls. Under different models, theEBI3rs428253 (OR = 0.831,Padd= 0.036; OR = 0.614,Prec= 0.033; OR = 0.591,Pcod2= 0.027) andIL-12Ars2243115 (OR = 0.674,Padd= 0.010; OR = 0.676,Pdom= 0.014; OR = 0.698,Phet= 0.027; OR = 0.694,Pcod1= 0.024) polymorphisms were associated with decreased risk of developing premature CAD. Some polymorphisms were associated with clinical and metabolic parameters. Significant different levels of IL-35 were observed inEBI3rs4740 and rs4905 genotypes only in the group of healthy controls. In summary, our study suggests that theEBI3andIL-12Apolymorphisms play an important role in decreasing the risk of developing premature CAD; it also demonstrates the relationship of theEBI3rs4740 and rs4905 genotypes with IL-35 levels in healthy individuals.
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26

Gustafson, Margaret A., and J. Christopher Fromme. "Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments." Molecular Biology of the Cell 28, no. 25 (December 2017): 3660–71. http://dx.doi.org/10.1091/mbc.e17-06-0370.

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At the Golgi complex, the biosynthetic sorting center of the cell, the Arf GTPases are responsible for coordinating vesicle formation. The Arf-GEFs activate Arf GTPases and are therefore the key molecular decision-makers for trafficking from the Golgi. In Saccharomyces cerevisiae, three conserved Arf-GEFs function at the Golgi: Sec7, Gea1, and Gea2. Our group has described the regulation of Sec7, the trans-Golgi Arf-GEF, through autoinhibition, positive feedback, dimerization, and interactions with a suite of small GTPases. However, we lack a clear understanding of the regulation of the early Golgi Arf-GEFs Gea1 and Gea2. Here we demonstrate that Gea1 and Gea2 prefer neutral over anionic membrane surfaces in vitro, consistent with their localization to the early Golgi. We illustrate a requirement for a critical mass of either Gea1 or Gea2 for cell growth under stress conditions. We show that the C-terminal domains of Gea1 and Gea2 toggle roles in the cytosol and at the membrane surface, preventing membrane binding in the absence of a recruiting interaction but promoting maximum catalytic activity once recruited. We also identify the small GTPase Ypt1 as a recruiter for Gea1 and Gea2. Our findings illuminate core regulatory mechanisms unique to the early Golgi Arf-GEFs.
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27

Bohner DDS, MSc, Ph, L. O. L., and L. H. M. Prates. "Compressive Strength of a Glass Ionomer Cement Under the Influence of Varnish Protection and Dietary Fluids." Odovtos - International Journal of Dental Sciences 20, no. 3 (August 31, 2018): 61–69. http://dx.doi.org/10.15517/ijds.2018.33607.

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The objective of this study was to evaluate the compressive strength of a glass ionomer cement (GIC) under the influence of varnish protection and dietary fluids. Eighty cylindrical test specimens were made from GIC and distributed into four groups (G1, G2, G3, G4) according to the dietary fluid. Each group was further divided into subgroups A and B according to the presence or absence of varnish protection. The eight subgroup samples were stored in distilled water for 30 days and received the following treatments for 14 days: G2A: varnish protection and immersion in soft drink, G2B: no varnish protection and immersion in soft drink, G3A: varnish protection and immersion in orange juice, G3B: no varnish protection and immersion in orange juice, G4A: varnish protection and immersion in yogurt, G4B: no varnish protection and immersion in yogurt. The immersion procedure was performed three times a day, for 15 minutes at a time, for a total of 14 days. The samples from subgroups G1A (with varnish) and G1B (without varnish) were used as controls and stored in distilled water only for 30 days. The samples were submitted to a compressive strength test after the immersion period. The results were analyzed using the ANOVA 2, Tukey test (5%) and Student’s t-test (5%). There were no significant differences between the subgroups, except for the subgroup with varnish protection and immersion in orange juice, which showed reduced GIC compressive strength.
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28

Bräuchle, Sebastian, Clivia Hejny, and Hubert Huppertz. "Synthesis and structural characterization of BaSr2Ge3O9." Zeitschrift für Naturforschung B 71, no. 12 (December 1, 2016): 1225–32. http://dx.doi.org/10.1515/znb-2016-0163.

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AbstractBaSr2Ge3O9 was prepared by high-temperature solid-state synthesis at 1100°C in a platinum crucible from barium carbonate, strontium carbonate, and germanium(IV) oxide. The compound crystallizes in the triclinic space group P1̅ (no. 2) isotypically to walstromite BaCa2Si3O9. The structure was refined from single-crystal X-ray diffraction data: a=7.104(5), b=10.060(7), c=7.099(5) Å, α=83.0(2), β=77.0(2), γ=70.2(2)°, V=464.3(6) Å3, R1=0.0230, and wR2=0.0602 for all data. BaSr2Ge3O9 is characterized by three-membered rings of germanate tetrahedra. There are three crystallographically different Ge sites (Ge1, Ge2, and Ge3) in each [Ge3O9]6− ring. The rings occur in layers with the apices of alternating rings pointing in opposite directions. The Sr2+ and Ba2+ ions are located in between. The Sr1 cation is eight-fold coordinated, while Sr2 is octahedrally surrounded by oxide anions, and the Ba cation again eight-fold coordinated.
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29

Tretyak, A. A. "Scientific and technical results of IX-th International congress of blast furnace men “Metallurgy of hot metal. Perspectives of development till the year of 2025”." Ferrous Metallurgy. Bulletin of Scientific , Technical and Economic Information 75, no. 1 (February 2, 2019): 5–9. http://dx.doi.org/10.32339/0135-5910-2019-1-5-9.

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From September 25 through September 27, 2018, the IX-th International congress of blast furnace men took place in Nizhny Tagil at the base of JSC “EVRAZ NTMK” named “Metallurgy of hot metal. Perspectives of development till the year of 2025”. It was organized by International Union of blast furnace men, “MetProm” Group and JSC “EVRAZ NTMK”. Heads and specialists of metallurgical, coke-making and chemical and machine-building plants, representatives of designing organizations, R&D institutes from Russia, CIS and foreign countries – all together 180 participants. At the congress, the specialists could receive information on modern developments, to exchange by opinions and experience. More than 60 reports were presented, which will be included in the digest of proceedings of the IX-th International congress of blast furnace men. Reports of foreign companies like “Danieli Corus”, “Paul Wurth”, “Primetals Technologies” and “GEA Russia” attracted a big interest. A particular interest was paid at the congress to estimation of status of coke and sinter production, as well as BF production under the current economic conditions, to determination of main ways of the industry development. Leading specialists discussed the ways of BF existing technologies perfection, methods of pig iron production alternative technologies implementation, perfection of means of control, implementation of information technologies, environmentally clean and resources saving technologies, aimed at increasing of products quality and production efficiency. At the forum, results of innovation projects implementation at the biggest steel-works were considered. During the last day of the congress work, the participants visited the JSC “EVRAZ NTMK” blast furnace No. 7, which has a volume of 2200 m3 and designing productivity – 2.5 mt/year of hot metal.
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30

"GEA Group, Germany." Pump Industry Analyst 2006, no. 12 (December 2006): 7. http://dx.doi.org/10.1016/s1359-6128(06)71701-3.

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"GEA Group, Germany." Pump Industry Analyst 2007, no. 6 (June 2007): 7. http://dx.doi.org/10.1016/s1359-6128(07)70245-8.

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32

"GEA Group, Germany." Pump Industry Analyst 2008, no. 7 (July 2008): 8. http://dx.doi.org/10.1016/s1359-6128(08)70291-x.

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"GEA Group, Germany." Pump Industry Analyst 2009, no. 8 (August 2009): 8. http://dx.doi.org/10.1016/s1359-6128(09)70325-8.

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"GEA Group, Germany." Pump Industry Analyst 2010, no. 7 (July 2010): 5. http://dx.doi.org/10.1016/s1359-6128(10)70279-2.

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"GEA Group, Germany." Pump Industry Analyst 2017, no. 8 (August 2017): 8. http://dx.doi.org/10.1016/s1359-6128(17)30313-0.

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"GEA Group, Germany." Pump Industry Analyst 2017, no. 12 (December 2017): 8. http://dx.doi.org/10.1016/s1359-6128(17)30440-8.

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"GEA Group, Germany." Pump Industry Analyst 2018, no. 4 (April 2018): 6. http://dx.doi.org/10.1016/s1359-6128(18)30096-x.

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"GEA Group, Germany." Pump Industry Analyst 2018, no. 6 (June 2018): 6. http://dx.doi.org/10.1016/s1359-6128(18)30154-x.

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"GEA Group, Germany." Pump Industry Analyst 2018, no. 9 (September 2018): 6. http://dx.doi.org/10.1016/s1359-6128(18)30239-8.

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"GEA Group, Germany." Pump Industry Analyst 2018, no. 11 (November 2018): 6. http://dx.doi.org/10.1016/s1359-6128(18)30295-7.

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"GEA Group, Germany." Pump Industry Analyst 2019, no. 4 (April 2019): 6. http://dx.doi.org/10.1016/s1359-6128(19)30095-3.

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"GEA Group, Germany." Pump Industry Analyst 2019, no. 6 (June 2019): 8. http://dx.doi.org/10.1016/s1359-6128(19)30159-4.

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43

"GEA Group, Germany." Pump Industry Analyst 2019, no. 9 (September 2019): 8. http://dx.doi.org/10.1016/s1359-6128(19)30249-6.

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"GEA Group, Germany." Pump Industry Analyst 2019, no. 11 (November 2019): 6. http://dx.doi.org/10.1016/s1359-6128(19)30298-8.

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"GEA Group, Germany." Pump Industry Analyst 2020, no. 6 (June 2020): 7. http://dx.doi.org/10.1016/s1359-6128(20)30169-5.

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"GEA Group, Germany." Pump Industry Analyst 2020, no. 9 (September 2020): 7. http://dx.doi.org/10.1016/s1359-6128(20)30258-5.

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47

"GEA Group, Germany." Pump Industry Analyst 2020, no. 11 (November 2020): 8. http://dx.doi.org/10.1016/s1359-6128(20)30327-x.

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48

"GEA Group, Germany." Filtration Industry Analyst 2017, no. 12 (December 2017): 10. http://dx.doi.org/10.1016/s1365-6937(17)30385-4.

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"GEA Group, Germany." Filtration Industry Analyst 2018, no. 4 (April 2018): 7. http://dx.doi.org/10.1016/s1365-6937(18)30095-9.

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"GEA Group, Germany." Filtration Industry Analyst 2018, no. 6 (June 2018): 8. http://dx.doi.org/10.1016/s1365-6937(18)30155-2.

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