Relevant bibliographies by topics / Gel formulation and in vitro diffusion study

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
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Academic literature on the topic 'Gel formulation and in vitro diffusion study'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Gel formulation and in vitro diffusion study"

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Amulya, Chikoti, and Bhaskar* Jimidi. "FORMULATION DEVELOPMENT AND IN-VITRO EVALUATION OF POSACONAZOLE LOADED TRANSFEROSOMES GEL." World Journal of Pharmaceutical Science and Research 2, no. 6 (2023): 273–80. https://doi.org/10.5281/zenodo.10931155.

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The goal of the current research was to create Posaconazole (PSZ) transferosome gel that would be effective against fungal infections. The gel was created by thin film hydration method. A study of the interactions between drugs and excipients was then conducted using the Fourier transform infrared (FTIR) spectroscopy method. The formulations were prepared and evaluated for measurement of pH, viscosity, spreadability, % entrapment efficiency, drug content estimation and in vitro diffusion study. Eight formulations were developed(PF1-PF8). In a Franz's diffusion cell, in vitro diffusion studies
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Gupta, Nitin, Giriraj T. Kulkarni, Pravin Kumar, and Rajendra Awasthi. "Grewia asiatica Mucilage: A Smart Gelling Polymeric Material for Pharmaceutical Applications In Vitro Studies." Current Materials Science 12, no. 2 (2020): 117–26. http://dx.doi.org/10.2174/2666145412666191125124644.

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Background: Natural plant-based materials have several advantages. They are biodegradable, biocompatible, non-toxic, cost-effective, environment friendly, easily available, and can undergo chemical modification. Objective: Grewia asiatica extracts contain various phytoconstituents and have therapeutic benefits such as antimicrobial and anti-diabetic properties. They form colloidal dispersions and make a highly viscous gel in water. Considering these properties of Grewia asiatica mucilage, the present work was aimed to investigate its application in the formulation of gel for the topical delive
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Suryakumari, CH, M. Narender, K. Umasankar, Siva Prasad Panda, S. N. Koteswara Rao, and Subhranshu Panda. "Formulation and Evaluation of Tacrolimus Transdermal Gel." Journal of Drug Delivery and Therapeutics 9, no. 6-s (2019): 110–18. http://dx.doi.org/10.22270/jddt.v9i6-s.3770.

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The present investigation is concerned with formulation and evaluation of Transdermal gels of Tacrolimus, anti-psoriasis drug, to circumvent the first pass effect and to improve its bioavailability with reduction in dosing frequency and dose related side effects. Twelve formulations were developed with varying concentrations of polymers like Carbopol 934P, HPMCK4M and Sodium CMC. The gels were tested for clarity, Homogeneity, Spreadability, Extrudability, Viscosity, surface pH, drug Content uniformity, in-vitro drug diffusion study and ex-vivo permeation study using rat abdominal skin. FTIR st
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Patel, Swati, Prabhat Jain, and Geeta Parkhe. "FORMULATION AND EVALUATION OF ACYCLOVIR LOADED NOVEL NANO-EMULSION GEL FOR TOPICAL TREATMENT OF HERPES SIMPLEX VIRAL INFECTIONS." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 265–70. http://dx.doi.org/10.22270/jddt.v8i5-s.1968.

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Acyclovir has low bioavailability mainly due to low solubility. This study aimed to formulate an optimized acyclovir (ACV) nanoemulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from herpes simplex viral infection. The dispersion solubility of acyclovir was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram nanoemulsion area was identified. The optimized formulations of nanoemulsions were subjected to thermodynamic stability tests. After stability study, stable formulation was characterized for drop
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Sharma, Shreyasi, Eisha Ganju, Neeraj Upmanyu, and Prabhat Jain. "THERAPEUTIC MICROEMULSION OF CURCUMIN FOR THE MANAGEMENT OF OSTEOARTHRITIS." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 341–47. http://dx.doi.org/10.22270/jddt.v8i5-s.1989.

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Curcumin (diferuloylmethane) is a natural polyphenolic compound with potent anti-inflammatory, anticancer and antioxidant activities. However, its bioavailability is low as it is poorly absorbed in the gastrointestinal tract. Microemulsions offer the potential to improve the solubility and bioavailability of bioactive compounds; the present work investigated the topical delivery potential of microemulsion gel loaded with curcumas. Curcumin microemulsion was prepared by spontaneous emul­sification method using oil (Oleic acid), surfactant:cosurfactant (Smix) (Ethanol and Tween 80, Span 80 and n
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Nikam, Shreya. "ANTI-ACNE GEL OF ISOTRETINOIN: FORMULATION AND EVALUATION." Asian Journal of Pharmaceutical and Clinical Research 10, no. 11 (2017): 257. http://dx.doi.org/10.22159/ajpcr.2017.v10i11.19614.

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Objective: Isotretinoin is a very effective drug in the treatment of acne vulgaris by topically. The objective of present study was formulation development of anti-acne gel using Isotretinoine and span 80 for topical delivery to cure nodulosystic acne vulgaris. Furthermore, the comparative study of all the evaluation parameters done with marketed formulation of same drug.Methods: Formulation of anti-acne gel of isotretinoin using Carbopol 940 as a polymer and incorporating isotretinoin in form of topical semi-solid gel using magnetic stirrer, Cremophor RH 40, and butylated hydroxytoluene. Drug
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Bharade, Shweta, Naveen Gupta, Shailesh Jain, Vishal Kapoor, and Dharmendra Singh Rajpoot. "Development of Micro-Emulsion Gel Based Topical Delivery of Salicylic Acid and Neem Oil for the Management of Psoriasis." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 186–91. http://dx.doi.org/10.22270/jddt.v9i4.3023.

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Microemulsions (MEs) are clear, thermodynamically stable systems. They were used to solubilise drugs and to improve topical drug availability. Salicylic acid (SA) is a keratolytic agent used in topical products with antimicrobial actions. This study aimed to formulate an optimized SA micro emulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from psoriasis infection. The dispersion solubility of SA was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram, micro emulsion area was identified. The optimize
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Dhananjay, Patil* Abdurrahman Helal Ahmed Mohammed Awais Sanaurrahman Rajashri More Karishma Shrivastav Rupesh Deore Vinod Bairagi. "FORMULATION, DEVELOPMENT AND IN VITRO EVALUATION OF SILDENAFIL CITRATE LIGNOCAINE HCl GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7921–37. https://doi.org/10.5281/zenodo.1403219.

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<em>The present study was undertaken to formulate, development and in vitro evaluation</em> <em>of Sildenafil Lignocaine gel</em>. <em>Sildenafil citrate is a drug of choice used in the treatment of premature ejaculation disorder</em>. <em>Topical gel has gained more and more importance because the gel based formulations are better percutaneously absorbed than creams and ointment bases</em>. <em>Therefore, topical gel of Sildenafil citrate was prepared using polymer of Carbopol 934 and triethanolamine at different proportions</em>. <em>The study encompasses compatibility studies using FTIR spe
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H.R., Thanushree, Kiran Kumar G B, and Ankit Acharya. "Formulation Development of Diclofenac Sodium Emulgel Using Aloe vera Gel for Transdermal Drug Delivery System." International Journal of Pharmaceutical Sciences and Nanotechnology 10, no. 5 (2017): 3858–65. http://dx.doi.org/10.37285/ijpsn.2017.10.5.7.

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Diclofenac sodium has many side effects like nausea, vomiting, GIT disorders. These side effects can be reduced by converting into emulgel formulations. The emulgel formulation of Diclofenac Sodium was prepared by incorporation method, using span 20 and tween 20 as non-ionic surfactants, clove oil and cinnamon oil as penetration enhancers, Aloe vera as a gel base and sesame oil as a solvent. The prepared emulgel formulations were evaluated for compatibility study, physical examination, viscosity, spreadability, in vitro diffusion studies, various release kinetic studies and stability studies.
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Jaber, Saba A., Halah T. Sulaiman, and Nawal A. Rajab. "Preparation, Characterization and In-Vitro Diffusion Study of Different Topical Flurbiprofen Semisolids." International Journal of Drug Delivery Technology 10, no. 01 (2020): 81–87. http://dx.doi.org/10.25258/ijddt.10.1.12.

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Flurbiprofen (FLB) is chemically 2-(3- fluoro-4-phenyl phenyl) propanoic acid. It is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of rheumatoid arthritis and osteoarthritis. Oral administration of this drug is associated with severe gastrointestinal side effects like ulceration and gastrointestinal bleeding. The solution to this problem lies in the fact that topically applied NSAIDs are safer than orally. This study aims to prepare different topical semisolid formulation of FLB as cream base (o/w), (w/o) and gel base using different gel-forming agents in different concen
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Dissertations / Theses on the topic "Gel formulation and in vitro diffusion study"

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Steyn, Heidi. "Formulation, in vitro release and transdermal diffusion of anti-inflammatory gel preparations containing diclofenac salts / by Heidi Steyn." Thesis, North-West University, 2010. http://hdl.handle.net/10394/3983.

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Most individuals are influenced by pain at some stage in their lives. It can either be of acute or chronic nature. An acute pain condition initiates and is treated within a time span of 12 weeks. Chronic pain can, however, take substantially longer to treat. Chronic pain may last up to 6 months after the original injury was sustained. The after effects of chronic pain can, however, take years to heal, but physical and emotional scars may even last much longer than the initial chronic ailment. In this study the skin was chosen as an area for delivery of non-steroidal anti-inflammatory drugs fo
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Benade, Reinette. "Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis / Reinette Benade." Thesis, North-West University, 2009. http://hdl.handle.net/10394/3982.

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Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. The disease presents in different forms, from superficial granulomas to deeper ulceration and necrosis. Tissue cultures, polymerase chain reactions or purified protein derivative staining is used for the diagnosis of CTB (Barbagallo etal., 2002:320). Since the current treatment for CTB is oral anti-tubercular regimens and no topical treatment is available yet (Barbagallo et
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Book chapters on the topic "Gel formulation and in vitro diffusion study"

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R, Dr Prabhu, Mr Venkatesh Babu, Ms Naveena N, and Mr Dhilip S. "SYNERGISTIC ANTIMICROBIAL EMULGEL FORMULATION OF QUERCETIN DIHYDRATE AND ZINC OXIDE: A POTENTIAL APPROACH FOR AZOLE-RESISTANT CANDIDIASIS TREATMENT." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 3. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bapn3ch20.

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This study investigated the synergistic effects of quercetin dihydrate and zinc oxide in an antimicrobial emulgel formulation. An emulgel, a combination of gel and emulsion, was investigated as an alternative to traditional gel formulations because of their hydrophobic properties. Different gelling agents and quercetin dihydrate and zinc oxide concentrations were used to prepare twelve antimicrobial emulgel formulations (F1-F12). The components did not interact chemically according to FTIR studies. In addition to color, homogeneity, consistency, phase separation, pH, viscosity, and spreadabili
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Chandra, S. Nigama, A. Anka Rao, and Amareswarapu V. Surendra. "Formulation and Evaluation of Minocycline Using Multiple Polymers." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00621.

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The present study was aimed at formulating and evaluating of controlled release tablets of Minocycline HCl using different polymers (guar gum, Xanthun gum and HPMC K100) at different proportions. The formulated controlled release tablets were evaluated for organoleptic properties and in vitro dissolution rate and then compared for optimum drug releasing formulation. The results of the in vitro drug release showed that the formulation containing Xanthun gum (1:1.5) has a zero-order drug release over a period of 24 h. In case of formulations containing guar gum and HPMCK100 the release of drug w
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Surekha, MKL, CF Sharon, Sindhu Abraham, and K. Shwetha. "Nanoformulated Epigallocatechin Gallate for its Potential Management of Oral Squammous Cell Carcinoma." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00376.

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Oral cancer is considered the most active cancer in oral cavity. Potentially malignant lesions in the oral epithelium can eventually develop into oral squamous cell carcinoma.Treating these lesions in the early stages could be an approach for early management of oral cancer. Green tea catechin, Epigallocatechin Gallate (EGCG) has been reported to have anti-oxidative, anti-inflammatory, and anti-tumor activities. In the present work, oral gels containing nanosponges of EGCG were prepared. Nanosponges were formulated using different concentrations of PVA and evaluated for percentage yield, drug
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Matlapudi, Megha Shyam, and Anka Rao Areti. "Formulation and Evaluation of Desonide Loaded Niosomes Prepared by Film Hydration Technique Using Box-Behnken Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00351.

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The use of topical calcineurin inhibitors is a treatment method for the chronic illness psoriasis. Topical medication administration is extremely difficult, nevertheless, because to the physicochemical makeup of psoriatic stratum corneum. The present study aims to explore the potential of niosomes to improve the topical delivery of Desonide (penetration and deposition) for effective treatment of psoriasis. The niosomes were prepared by film hydration method using Cholesterol, Span 80 and Carbopol 940 (gelling agent). A Box-Behnken (BB) design, using Design-Expert® software, was employed to sta
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Bin Zafar Auniq, Reedwan, Namon Hirun, and Upsorn Boonyang. "Three-Dimensionally Ordered Macroporous-Mesoporous Bioactive Glass Ceramics for Drug Delivery Capacity and Evaluation of Drug Release." In Ceramic Materials [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.95290.

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Bioactive glass ceramics (BGCs) have been used in orthopedic and dentistry due to having better osteoconductive and osteostimulative properties. This study aimed to evaluate and compare the drug release properties of two different BGCs; 45S5 and S53P4. The BGCs were composed with four phases of SiO2 – CaO – Na2O – P2O5 system, synthesized by sol–gel method using dual templates; a block-copolymer as mesoporous templates and polymer colloidal crystals as macroporous templates, called three-dimensionally ordered macroporous-mesoporous bioactive glass ceramics (3DOM-MBGCs). In vitro bioactivity te
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Conference papers on the topic "Gel formulation and in vitro diffusion study"

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Pasril, Yusrini, and Keisha Zulfira. "The influence of combination of Apis mellifera honey and Ananas comosus fruit extract (100% concentration) in gel formulation on teeth whitening (In Vitro study)." In THE 2ND NEW DENTAL RESEARCH EXHIBITION AND MEETING (NEW DREAM) 2024. AIP Publishing, 2025. https://doi.org/10.1063/5.0273873.

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Sahoo, Debasish, Virendra Vaishnav, Tanushree Chatterjee, and Navita Gupta. "HERBAL DIETARY SUPPLEMENT – A MODERN APPROACH IN COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM) IN HEALTH CARE SCIENCE." In International Conference on Public Health and Medical Sciences. Goodwood Conferences, 2022. http://dx.doi.org/10.35912/icophmeds.v1i1.24.

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Preliminary pharmacological study of herbal based dietary supplement formulation based on extracts or whole plants derived from fruits, root, berries, macrofungus and leaves as a promising, safe and effective alternative to synthetic and pharmaceutical dietary supplements, in-vitro studies such as antibacterial, anti-oxidant and anti-inflammatory activity for extract of dietary supplements. Nutritional assessment of nutritional attributes as suggested by AOAC method, Phytochemical analysis by standard chemical procedures, Quantitative estimate Alkaloid, Flavonoid, Phenolic, Tannin. In-vitro st
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Reports on the topic "Gel formulation and in vitro diffusion study"

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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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