Academic literature on the topic 'Gemifloxacino'

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Journal articles on the topic "Gemifloxacino"

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Kleinkauf, Niels, Grit Ackermann, Reiner Schaumann, and Arne C. Rodloff. "Comparative In Vitro Activities of Gemifloxacin, Other Quinolones, and Nonquinolone Antimicrobials against Obligately Anaerobic Bacteria." Antimicrobial Agents and Chemotherapy 45, no. 6 (2001): 1896–99. http://dx.doi.org/10.1128/aac.45.6.1896-1899.2001.

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ABSTRACT The in vitro activity of gemifloxacin was compared to that of other quinolone and nonquinolone antimicrobials against 204 anaerobes by the agar dilution technique. The data indicate that gemifloxacin has a rather selective anaerobic activity. Most Peptostreptococcus, Porphyromonas, and Fusobacterium species are susceptible, while gemifloxacin's activity against other gram-negative anaerobes appears to be variable.
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MacGowan, Alasdair P., and Karen E. Bowker. "Mechanism of Fluoroquinolone Resistance Is an Important Factor in Determining the Antimicrobial Effect of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model." Antimicrobial Agents and Chemotherapy 47, no. 3 (2003): 1096–100. http://dx.doi.org/10.1128/aac.47.3.1096-1100.2003.

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ABSTRACT Antibacterial effect and emergence of resistance to gemifloxacin and levofloxacin were studied in an in vitro pharmacokinetic model of infection. A panel of Streptococcus pneumoniae strains with known mechanisms of resistance were used; two strains had no known resistance mechanism, two had efflux pumps, three had gyrA plus parC mutations, and one had only a parC mutation. Gemifloxacin MICs were in the range of 0.016 to 0.25 mg/liter, and levofloxacin MICs ranged from 1 to 16 mg/liter. Antimicrobial effect was measured by area under the bacterial-kill curve up to 72 h, and emergence o
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Barrett, Matthew J., and Ivan S. Login. "Gemifloxacin-Associated Neurotoxicity Presenting as Encephalopathy." Annals of Pharmacotherapy 43, no. 4 (2009): 782–84. http://dx.doi.org/10.1345/aph.1l621.

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Objective: To report a case of acute encephalopathy associated with ingestion of gemifloxacin, a fluoroquinolone. Case Summary: A 67-year-old woman presented to the emergency department with an acute alteration in mental status. Twenty-four hours earlier she had taken one 320-mg tablet of her husband's gemifloxacirt prescription to treat symptoms of a mild upper respiratory infection. During her initial evaluation at our institution, the woman was dysphasia, unable to follow commands, and agitated, suggesting encephalopathy. A thorough diagnostic investigation did not reveal any structural, me
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Islinger, Florian, Rene Bouw, Mathias Stahl, et al. "Concentrations of Gemifloxacin at the Target Site in Healthy Volunteers after a Single Oral Dose." Antimicrobial Agents and Chemotherapy 48, no. 11 (2004): 4246–49. http://dx.doi.org/10.1128/aac.48.11.4246-4249.2004.

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ABSTRACT Free gemifloxacin concentrations in the interstitial space fluid of skeletal muscle and subcutaneous adipose tissue were measured by means of in vivo microdialysis to characterize the ability of gemifloxacin to penetrate human soft tissues. Twelve healthy volunteers received a single oral dose of 320 mg of gemifloxacin. The mean areas under the concentration-time curves from 0 to 10 h (AUC0-10) were significantly higher for soft tissue than for unbound gemifloxacin in plasma (P < 0.05). The ratios of the mean AUC0-10 for tissue to the AUC0-10 for free gemifloxacin in plasma were 1.
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Lowe, Matthew N., and Harriet M. Lamb. "Gemifloxacin." Drugs 59, no. 5 (2000): 1137–47. http://dx.doi.org/10.2165/00003495-200059050-00009.

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Mandell, Lionel A. "Gemifloxacin." Drugs 59, no. 5 (2000): 1148. http://dx.doi.org/10.2165/00003495-200059050-00010.

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Finch, Roger G. "Gemifloxacin." Drugs 59, no. 5 (2000): 1148. http://dx.doi.org/10.2165/00003495-200059050-00011.

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&NA;. "Gemifloxacin." Reactions Weekly &NA;, no. 1305 (2010): 17. http://dx.doi.org/10.2165/00128415-201013050-00056.

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&NA;. "Gemifloxacin." Reactions Weekly &NA;, no. 1245 (2009): 19. http://dx.doi.org/10.2165/00128415-200912450-00056.

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Avenell, Natalie. "Gemifloxacin." Inpharma Weekly &NA;, no. 1186 (1999): 9–10. http://dx.doi.org/10.2165/00128413-199911860-00014.

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Dissertations / Theses on the topic "Gemifloxacino"

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Tavares, Vanessa Franco. "Determinação quantitativa de gemifloxacino por cromatografia líquida de alta eficiência e eletroforese capilar." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-01032013-094155/.

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Gemifloxacino (GMFLX) é um agente fluorquinôlonico, antibacteriano recentemente desenvolvido que apresenta um amplo espectro de atividade. O objetivo deste estudo foi desenvolver e validar métodos seletivos e sensíveis para a determinação quantitativa de GMFLX em comprimidos revestidos por cromatografia líquida de alta eficiência (CLAE) e eletroforese capilar de zona (CZE). O método por CLAE foi realizado em uma coluna LiChrospher® 100 RP-8e, 5µm (125 x 4 mm) e uma fase móvel composta por tetraidrofurano:água (25:75, v/v) com 0.5% de trietilamina e pH ajustado para 3.0 com ácido orto
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Paim, Clésio Soldateli. "Mesilato de gemifloxacino : desenvolvimento e validação de métodos analíticos, teste de dissolução e estudo de estabilidade." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/60371.

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A análise de fármacos é fundamental nas diversas fases do desenvolvimento farmacêutico, tais como em estudos de formulação, estabilidade e controle de qualidade do produto. O mesilato de gemifloxacino (MGF), liberado para uso clínico no Brasil em novembro de 2006 com o nome comercial de Factive®, é uma fluorquinolona indicada para o tratamento da exacerbação aguda da bronquite crônica e da pneumonia adquirida da comunidade. A literatura pesquisada apresenta poucos relatos de determinação quantitativa e de estudos de estabilidade do fármaco em comprimidos revestidos. Anteriormente aos estudos,
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Kekukh, Elena [Verfasser]. "Untersuchungen zur In-vitro-Empfindlichkeit von Borrelia burgdorferi gegen Ciprofloxacin, Sitafloxacin, Gemifloxacin, Cethromycin, Doxycyclin und Ceftriaxon / vorgelegt von Elena Kekukh." 2007. http://d-nb.info/1001733622/34.

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Books on the topic "Gemifloxacino"

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Blokdijk, G. J. Gemifloxacin Mesylate; A Complete Guide. CreateSpace Independent Publishing Platform, 2018.

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Book chapters on the topic "Gemifloxacino"

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Al-Hadiya, Badraddin M. H., and Ashraf M. M. Mahmoud. "Gemifloxacin." In Profiles of Drug Substances, Excipients and Related Methodology. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-387667-6.00004-x.

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"Gemifloxacin." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.00799-x.

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"Gemifloxacin." In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier, 2006. http://dx.doi.org/10.1016/b0-44-451005-2/00474-5.

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Eliopoulos, George. "Gemifloxacin." In Kucers' The Use of Antibiotics Sixth Edition. CRC Press, 2010. http://dx.doi.org/10.1201/b13787-114.

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"FACTIVE (Gemifloxacin)." In Antibiotics Manual. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119220787.ch71.

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"Gemifloxacin Mesylate." In Hale’s Medications & Mothers’ Milk™ 2019. Springer Publishing Company, 2018. http://dx.doi.org/10.1891/9780826150356.0458.

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Conference papers on the topic "Gemifloxacino"

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Kim, Seo Yun, Ji Yeon Lee, Eun Young Heo, Chang-Hoon Lee, Hee Soon Chung, and Deog Kyeom Kim. "Impact Of Gemifloxacin On Delaying The Treatment Of Tuberculosis." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3312.

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Xi, Hui-ping, and Xiu-wei Fang. "The Fluorescence Characteristic of AO-RB-SDS-GMFX and the Determination of Gemifloxacin." In International Academic Workshop on Social Science (IAW-SC-13). Atlantis Press, 2013. http://dx.doi.org/10.2991/iaw-sc.2013.145.

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