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Dissertations / Theses on the topic 'Gene expression profiling'

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Published: 4 June 2021

Last updated: 25 July 2025

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1

Muszynska, Dorota. "Gene expression profiling in Keratoconus." Thesis, Queen's University Belfast, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602693.

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Keratoconus (MIM#148300), a common bilateral, progressive corneal thinning disorder, is the leading indication for corneal transplantation in the developed world. Keratoconus usually arises in the teenage years and presents a significant health burden in work-age adults. Despite the visual and social impact of keratoconus, our lack of understanding of the molecular pathology of keratoconus is a major obstacle to the development of new therapeutic approaches. This study represents the first reported application of massively parallel sequencing of mRNA (RNA-Seq) to perform whole genome transcrip

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Leonard, Pauline Catherine. "Gene expression profiling of osteosarcoma." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445814/.

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Purpose: The aim of the work described in this thesis was to determine whether needle core and open biopsies from osteosarcoma (OS) provide sufficient quality of mRNA for cDNA array analyses which might then provide insights into the expression profile of OS. Experimental Design: Sixteen samples collected from OS and two established cell lines were used for array analyses. A primary cell culture was also established from one of the OS biopsies. Total RNA was extracted and probes generated for cDNA arrays. A reference probe was included for computational analyses. Results: cDNA probes were made

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Hägg, Sara. "Gene Expression Profiling of Human Atherosclerosis." Doctoral thesis, Linköpings universitet, Biologiska Beräkningar, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-52085.

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Atherosclerosis is a progressive inflammatory disease that causes lipid accumulation in the arterial wall, leading to the formation of plaques. The clinical manifestations of plaque rupture—stroke and myocardial infarction—are increasing worldwide and pose an enormous economic burden for society. Atherosclerosis development reflects a complex interaction between environmental exposures and genetic predisposition. To understand this complexity, we hypothesized that a top-down approach—one in which all molecular activities that drive atherosclerosis are examined simultaneously—is necessary to hi

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4

Bain, Peter A., and n/a. "Gene Expression Profiling of Cylindrospermopsin Toxicity." Griffith University. School of Biomolecular and Physical Sciences, 2007. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20080404.145834.

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Cylindrospermopsin (CYN) is a toxic alkaloid produced by several freshwater cyanobacterial species, the most prevalent in Australian waters being Cylindrospermopsis raciborskii. The occurrence of CYN-producing cyanobacteria in drinking water sources worldwide poses a potential human health risk, with one well-documented case of human poisoning attributed to the toxin. While extensive characterisation of CYN-induced toxicity has been conducted in rodents both in vivo and in primary cell cultures, little is known about mechanisms of toxicity in human cell types. This thesis describes studies und

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Beijnum, Judith Rosina van. "Gene expression profiling of tumor angiogenesis." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 2006. http://arno.unimaas.nl/show.cgi?fid=7710.

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6

Al-Halabi, Hani. "Gene expression profiling in adult Medulloblastoma." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107616.

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Medulloblastoma (MB) represents approximately 1% of adult brain tumours, and as such is a poorly studied disease. It exhibits different clinical manifestations and outcome in adults, yet it is still treated as per pediatric protocols. Recently, gene expression profiling studies suggested the existence of at least 4 molecular subtypes in pediatric MB, characterized by distinct genetic profiles, activation of oncogenic pathways and varied clinical outcomes. This has refined our ability to classify MB, select tumors for targeted therapy and is leading the way to individualized medicine. It is unk

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7

Goh, Huey Tse. "Profiling cardiac gene expression during endotoxaemia." Thesis, University of Nottingham, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523087.

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8

Brooks, W. M. "Profiling gene expression in Alzheimer's disease." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596943.

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Alzheimer’s disease is a debilitating neurodegenerative disease expected to increase in prevalence during the next few decades. Familial Alzheimer’s disease cases have revealed some molecules that appear to be involved in the disease pathogenesis. However, factors fully explaining the vast majority of case of Alzheimer’s disease which are sporadic, wait to be determined. The present study conducted a broad survey of gene expression in Alzheimer’s disease post mortem tissue with the aim of identifying gene expression products involved in this disease. Initially, a study was carried out to deter

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9

Cleator, Susan Jane. "Gene expression profiling of breast cancers." Thesis, Institute of Cancer Research (University Of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423120.

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10

Bain, Peter A. "Gene Expression Profiling of Cylindrospermopsin Toxicity." Thesis, Griffith University, 2007. http://hdl.handle.net/10072/367068.

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Cylindrospermopsin (CYN) is a toxic alkaloid produced by several freshwater cyanobacterial species, the most prevalent in Australian waters being Cylindrospermopsis raciborskii. The occurrence of CYN-producing cyanobacteria in drinking water sources worldwide poses a potential human health risk, with one well-documented case of human poisoning attributed to the toxin. While extensive characterisation of CYN-induced toxicity has been conducted in rodents both in vivo and in primary cell cultures, little is known about mechanisms of toxicity in human cell types. This thesis describes studies und

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11

Paon, Lenaic Marie Pierre. "Gene expression profiling of metastatic gastric cancer." Thesis, University of Liverpool, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490659.

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Gastric cancer is one of the main cancers in the world, and is responsible for a large number of deaths each year. In Europe, the main issue is that it is only detected at latter stages, when metastases have developed. Although metastasis is the main cause of death from such tumours, the process is a very complex one and still not fully understood. In order to unravel this mechanism, microarrays have been used to study the expression pattern of a large number of genes in primary tumours and metastatic samples. These studies aim at indentifying genes that may playa role in metastasis. A number

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12

Quinn, Michael Corwin James, and n/a. "Gene expression profiling of human granulosa cells." University of Otago. Department of Anatomy & Structural Biology, 2005. http://adt.otago.ac.nz./public/adt-NZDU20070501.144002.

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Human granulosa cells play an important role in the follicle, providing the oocyte with nutrients and growth factors to ensure successful ovulation. Normal granulosa cell functioning is thus crucial to human fertility. By studying their transcriptome, the mechanisms underpinning follicle development and infertility will be better understood. In this study, granulosa cells were retrieved at the time of oocyte removal for in vitro fertilization (IVF). Cells were purified through a combination of a Percoll gradient to remove red blood cells and positive selection of granulosa cell aggregations.

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13

Geatrell, Jenny. "Apoptosis gene expression profiling in lens development." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54644/.

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During lens development, epithelial cells located at the equatorial region of the lens undergo terminal differentiation to form fibre cells resulting in cell elongation and degradation of all intracellular organelles. Failure to complete this process successfully can result in cataract. This process is thought to be an attenuated form of classical apoptosis. This study was completed to give a comprehensive analysis of apoptosis genes in the developing mouse lens. Macroarrays containing 243 immobilised cDNAs with a known role in apoptosis were utilised to examine the gene expression at differen

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14

Dennis, Jayne L. "Gene expression profiling and classification of adenocarcinoma." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411836.

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15

Sharp, Margaret. "Global gene expression profiling of canine lymphoma." Thesis, Sharp, Margaret (2017) Global gene expression profiling of canine lymphoma. PhD thesis, Murdoch University, 2017. https://researchrepository.murdoch.edu.au/id/eprint/38017/.

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Lymphoma, a cancer of lymphoid tissue, is a relatively common form of canine malignancy, typically affecting middle-aged to older dogs, with a higher prevalance among certain breeds. Treatment choices and more precise diagnosis and classification for this disease are currently limited by deficiencies in our understanding of the underlying pathogenic mechanisms and by a lack of useful biomarkers. As with other forms of cancer, canine lymphoma is likely to be a molecular disease resulting from the abnormal expression of genes involved in fundamental cell processes such as cell differentiation, p

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16

Gould, Barbara. "The genomics of labour : global gene expression profiling and oxytocin receptor gene expression." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84251.

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Premature labour and subsequent premature birth is a leading cause of neonatal morbidity and mortality. We studied marine labour at term and preterm with models of intrauterine infection and ovariectomy using Affymetrix microarray U74Av2 (containing 12,488 probe sets) and real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) to identify novel candidate genes involved in normal and preterm labour. Strict statistical analysis revealed 320, 188, and 74 genes to be significantly induced or suppressed during normal, infection-induced, and ovariectomy-induced labour,

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17

Liu, Zhilin. "Gene expression profiling of bovine ovarian follicular selection." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4490.

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Thesis (Ph.D.)--University of Missouri-Columbia, 2006.<br>The entire dissertation/thesis text is included in the research.pf file; the official abstract appears in the short.pf file (which also appears in the research.pf); a non-technical general description, or public abstract, appears in the public.pf file. Title from title screen of research.pf file (viewed on May 6, 2009) Vita. Includes bibliographical references.

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18

Smith, Nolan R. "Gene Expression Profiling in Heat Stressed Scaphirhynchus Sturgeon." OpenSIUC, 2020. https://opensiuc.lib.siu.edu/theses/2759.

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The pallid sturgeon (Scaphirhynchus albus) is a federally endangered species, endemic to the Mississippi River drainage, stretching from the upper Missouri River in Montana to the Mississippi River, and continuing to the Gulf of Mexico. They are largely sympatric throughout this range with a close congener, the shovelnose sturgeon (S. platorhynchus), although speciation may have occurred when they were isolated in different refugia. In this study, we examined gene expression differences among pallid and shovelnose sturgeon families in response to heat stress. Gene expression can be considered

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19

Arlinde, Christina. "Gene expression profiling in animal models of alcoholism /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-133-4/.

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20

Dhoogra, Minishca. "Gene expression profiling of polyamine-depleted Plasmodium falciparum." Diss., Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-12132007-103643/.

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21

Hughes, B. "Gene expression profiling of quiescent peripheral T lymphocytes." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604742.

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The <i>lymphopenia </i>mutation, a key factor in the development of autoimmune diabetes mellitus in the BB rat, reduces the <i>in vitro </i>life-span of TCR<sup>hi </sup>single-positive thymocytes and peripheral T cells due to an increased rate of apoptosis. It was proposed that the <i>lymphopenia </i>mutation prevents the accumulation of a normal T cell pool, including regulatory subsets, without preventing the activation and proliferation of reactive T cells, thereby creating conditions appropriate for the development of uncontrolled autoimmune disease. To understand the processes affecting

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22

Warner, Giles C. "Gene expression profiling of head and neck cancer." Thesis, Queen Mary, University of London, 2004. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1857.

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The purpose of this study was to classify oral squamous cell carcinomas (OSCCs) based on their gene expression profiles, to identify differentially expressed genes in these cancers, and to correlate genetic deregulation with clinical-histopathological data and patient outcome. After conducting proof of principle experiments utilizing six head and neck squamous cell carcinomas (HNSCCs) cell lines, the gene expression profiles of 20 OSCCs and subsequently an additional 8 OSCCs were determined using cDNA microarrays containing 19,200 sequences and the Binary Tree-Structured Vector Quantization (B

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23

Hime, Audrey Elise. "Gene expression-based profiling for studying dystonia pathogenisis." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12421.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>This project mainly focuses on DYT6 dystonia and its causative gene: THAP1, which encodes a proposed transcription factor, THAP1, which exhibits sequencespecific and zinc-dependent DNA-binding activity. Over 50

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24

Nathanson, Jason Lawrence. "Cell type specific gene expression profiling and targeting /." Diss., View abstract only; access to full text of dissertation for UC campuses will be available after September 1, 2010, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3320635.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed September 24, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 135-150).

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25

Ståhlberg, Nina. "Gene expression profiling in molecular studies of hormone actions /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-706-1/.

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26

Lam, Chi-leung David. "Gene expression profiling in non-small cell lung cancer." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38585777.

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27

Tan, Wei Min. "Single cell gene expression profiling of human epidermal keratinocytes." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609685.

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28

Mulaw, Medhanie Assmelash. "Early target genes of CALM/AF10 as revealed by gene expression profiling." Diss., kostenfrei, 2009. http://edoc.ub.uni-muenchen.de/10480/.

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29

Forsman, M. (Minna). "Histological characteristics and gene expression profiling of Dupuytren’s disease." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526211671.

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Abstract Dupuytren’s disease is a Caucasian male-dominant disease that affects the palmar fascia. Incidence grows with age, but persons with strong diathesis seem to develop the disease at an earlier age than the majority of the diseased. Myofibroblasts are histopathologically the main cell type in DD tissue. Despite scientific research, the aetiology of the disease is still unrevealed. Only genetic susceptibility is generally accepted as predisposing to DD. Available treatment has thus far been unsatisfactory, because only symptoms can be cured to date.The disease recurs. With genetic suscept

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30

Rysä, J. (Jaana). "Gene expression profiling in experimental models of cardiac load." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514287664.

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Abstract Cardiac hypertrophy provides an adaptive mechanism to maintain cardiac output in response to increased workload, and although initially beneficial, hypertrophy eventually leads to heart failure, a major cause of morbidity and mortality in Western countries. The hypertrophic response in cardiac myocytes is accompanied by e.g. activation of signal transduction pathways, such as mitogen-activated protein kinases (MAPKs), and complex changes in gene programming. The purpose of this study was to characterize gene expression patterns in experimental models of cardiac load by using high-thro

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Lam, Chi-leung David, and 林志良. "Gene expression profiling in non-small cell lung cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38585777.

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32

Bergman, Julia. "Aspects of Gene Expression Profiling in Disease and Health." Doctoral thesis, Uppsala universitet, Molekylär och morfologisk patologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-312939.

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The aim of this thesis is to in various ways explore protein expression in human normal tissue and in cancer and to apply that knowledge in biomarker discovery. In Paper I the prognostic significance of RNA-binding motif protein 3 (RBM3) is explored in malignant melanoma. To further evaluate the prognostic significance of RBM3 expression was assessed in 226 incident cases of malignant melanoma from the prospective populationbased cohort study Malmö Diet and Cancer Study using tissue microarray technique (TMA). RBM3 was shown to be down regulated in metastatic melanoma and high nuclear expressi

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33

Chang, Xiaoqing. "Bayesian Mixtures and Gene Expression Profiling with Missing Data." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1226090856.

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34

Nascimento, Helvia. "Caracterização da expressão genica de celulas tumorais de pacientes com adenocarcinoma esporadico do colon." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310956.

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Orientador: Carmen Silvia Passos Lima, Fernando Ferreira Costa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-12T11:53:50Z (GMT). No. of bitstreams: 1 Nascimento_Helvia_D.pdf: 1845231 bytes, checksum: 16f227072d706aacb01f06165bd8a553 (MD5) Previous issue date: 2007<br>Resumo: Os mecanismos moleculares envolvidos na origem do adenocarcinoma de cólon esporádico (ACE) ainda não estão completamente elucidados. Recentemente, o método da análise seriada da expressão gênica (SAGE) foi descrito como eficaz para identifica

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35

McKinney, Eoin Fergal. "Gene expression profiling in systemic vasculitis and systemic lupus erythematosus." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609786.

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36

Granberg, Fredrik. "Global Profiling of Host Cell Gene Expression During Adenovirus Infection." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7221.

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37

McKethan, Brandon Lee Dickstein Rebecca. "Gene expression profiling of the nip mutant in Medicago truncatula." [Denton, Tex.] : University of North Texas, 2007. http://digital.library.unt.edu/permalink/meta-dc-3940.

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38

Baken, Kirsten Annika. "Immunotoxicogenomics gene expression profiling as a tool to study immunotoxicity /." [Maastricht] : Maastricht : Universitaire Pers Maastricht ; University Library, Universiteit Maastricht [host], 2007. http://arno.unimaas.nl/show.cgi?fid=9329.

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39

Will, Malcolm B. "Gene expression profiling of mesenchymal stem cells aged in vitro." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1964/.

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Mesenchymal Stem Cells (MSC’s) have shown promise as a cell-based therapy for myocardial repair. However, MSC’s have a finite replicative lifespan and lose proliferative and differentiation capacity during expansion in vitro. Therefore, understanding the molecular mechanisms that regulate ageing and senescence of MSC’s should enhance our ability to use these cells in cell-based approaches and give insight into mechanisms of tissue ageing. We established MSC cultures from the sternal bone marrow of eight donors undergoing coronary artery bypass surgery. After thirty population doublings (nine p

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Romero, Claudia. "CELLULAR IMMUNE RESPONSE AND GENE EXPRESSION PROFILING IN CROHN'S DISE." Doctoral diss., University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2704.

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Despite the chronic debate in the etiology of crohn's disease (cd), a debilitating inflammatory bowel disease (ibd) closely related to ulcerative colitis (uc), an emerging interest in a possible mycobacterial role has been marked. Granuloma and pathologic manifestations in cd resemble aspects found in tuberculosis, leprosy and paratuberculosis. The latter, a chronic enteritis in cattle, goat, sheep and primates, which is similar to human enteritis, also known as cd, is caused by a fastidious, slow growing mycobacterium avium subspecies paratuberculosis (map). Due to the similarities between cd

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Durrant, Wendy E. "Gene expression profiling of the Cf-9 dependent defence response." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323392.

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42

Menon, Suraj. "Integration and biological interpretation of microarry gene expression profiling data." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55858/.

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Many different strategies have been developed for the analysis of microarray data and these have a significant influence on the level and quality of knowledge that may be achieved from a microarray-based experiment. Two such strategies are explored in this thesis. Part A of this thesis describes explorations of a resource-efficient strategy that could allow for large-scale integration of microarray data in an unsupervised fashion. For this purpose, comparisons were carried out between a series of genelists manually extracted from the literature, representing a disparate set of microarray exper

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McKethan, Brandon Lee. "Gene Expression Profiling of the nip Mutant in Medicago truncatula." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3940/.

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The study of root nodule symbiosis between nitrogen-fixing bacteria and leguminous plant species is important because of the ability to supplement fixed nitrogen fertilizers and increase plant growth in poor soils. Our group has isolated a mutant called nip in the model legume Medicago truncatula that is defective in nodule symbiosis. The nip mutant (numerous infections with polyphenolics) becomes infected by Sinorhizobium meliloti but then accumulates polyphenolic defense compounds in the nodule and fails to progress to a stage where nitrogen fixation can occur. Analysis of the transcripto

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Jacobsen, Mette Dorph. "Analysis of Candida albicans gene expression using single cell profiling." Thesis, University of Aberdeen, 2005. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU193586.

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Candida albicans is an important fungal pathogen of humans and shows great flexibility in adapting to diverse host niches, which present different ambient pH values, changes in O2 concentrations, various different substrates for metabolism and host defence mechanisms. Knowledge on how these environmental stimuli are sensed by the fungal cells is limited. Here, a bioinformatics approach was employed to search for putative receptors in the C. albicans genome. However, no obvious novel receptor candidates were identified that might function in environmental sensing in C. albicans. Using a GFP-bas

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Kan, Takatsugu. "Gene expression profiling in human esophageal cancers using cDNA microarray." Kyoto University, 2003. http://hdl.handle.net/2433/148738.

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Bury, Joanna J. "Gene expression profiling of peripheral tissues in amyotrophic lateral sclerosis." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/10101/.

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Background: Amyotrophic Lateral Sclerosis, in which cortical and spinal motor neurons degenerate, is a late onset neurodegenerative condition that accounts for ~1 in 400 UK deaths, typically within 3-5 years from the initial manifestations of disease. It forms part of a broad spectrum of clinically, genetically as well as pathologically heterogeneous disorders that include behavioural variant frontotemporal lobar degeneration (bvFTLD). A large intronic hexanucleotide G4C2 repeat expansion of >30 copies was recently identified, in 2011, in the previously uncharacterised chromosome 9 open readin

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Foerster, Susann. "Gene expression profiling of human lymph node-positive gastric adenocarcinomas." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16259.

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In dieser Arbeit wurden Genexpressionsprofile diffuser und intestinaler Magenadenokarzinome mittels Microarray-Technik erstellt. Der intestinale Typ konnte als stark proliferierender Tumor mit signifikanter Überexpression von zellzyklusrelevanten Genen definiert werden, während der diffuse Typ als stark stromaabhängig mit signifikanter Überexpression von Genen der extrazellulären Matrix hervortrat. Thrombospondin 4 (THBS4) wurde dabei als das am stärksten differentiell exprimierte Gen identifiziert, wobei seine mRNA in diffusen Tumoren eminent überexprimiert wird. Immunhistochemische Studien b

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Carlén, Lina. "Characterization of psoriasis lesions by protein expression profiling /." Stockholm : Karolinska institutet, 2006. http://diss.kib.ki.se/2006/91-7140-808-8/.

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Boräng, Stina. "Subtracted Approaches to Gene Expression Analysis in Atherosclerosis." Doctoral thesis, KTH, Biotechnology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3684.

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<p>Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. A moreeffective approach than exploring the whole content of genesexpressed under certain conditions is to study fingerprintassays or to use subtracted cDNA libraries to identify onlydifferentially expressed genes.</p><p>The objective for the work in this thesis has been toexplore differentially expressed gene

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50

Bjork, Kathe Elizabeth. "Robust identification of differential gene expression and discrimination /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2006.

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Thesis (Ph.D. in Biostatistics) -- University of Colorado at Denver and Health Sciences Center, 2006.<br>Typescript. Includes bibliographical references (leaves 237-239). Free to UCDHSC affiliates. Online version available via ProQuest Digital Dissertations;

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