Academic literature on the topic 'Gene frequency'

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Journal articles on the topic "Gene frequency"

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Robbins, G. "GENE FREQUENCY FOR THALASSAEMIA." Lancet 325, no. 8428 (1985): 579. http://dx.doi.org/10.1016/s0140-6736(85)91235-8.

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A, Abdelmoktader. "TLR 1,3 Receptor Gene Polymorphism in Egyptian Patients With Behcets Disease." Virology & Immunology Journal 6, no. 3 (2022): 1–8. http://dx.doi.org/10.23880/vij-16000298.

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Behçet’s disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulcerations, ocular inflammations, and skin lesions. The ethology of the disease is currently unknown but evidences suggested that there is a strong genetic component mediating the chronicity of the disorder. The disease is characterized by infiltration of lymphocytes and neutrophils into the affected organs. APCs (Antigen Presenting Cells): It express receptor called (TLR) Toll like receptor which are one of PRR (pattern recognition receptor) and essential components of the innate immune system a
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Maheshri, Narendra. "Gene Expression: Dialing Up the Frequency." Current Biology 18, no. 24 (2008): R1136—R1139. http://dx.doi.org/10.1016/j.cub.2008.10.032.

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Caballero-Franco, C., and S. Kissler. "The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells." Genes & Immunity 17, no. 4 (2016): 228–38. http://dx.doi.org/10.1038/gene.2016.16.

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M Kurrse, Rawya, and Leena B Mirghani. "Frequency of (G428A) Polymorphism within FUT2 Gene among Symptomatic UTI Diseases in Sudanese Patients." International Journal of Scientific Engineering and Research 4, no. 6 (2016): 45–47. https://doi.org/10.70729/ijser15830.

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Takahama, Kazutaka, Masayoshi Matsuoka, Kazuhiro Nagahama, and Takahira Ogawa. "High-Frequency Gene Replacement in Cyanobacteria Using a Heterologous rps12 Gene." Plant and Cell Physiology 45, no. 3 (2004): 333–39. http://dx.doi.org/10.1093/pcp/pch041.

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Lewis, R. M., B. Grundy, and L. A. Kuehn. "Predicting population gene frequency from sample data." Animal Science 78, no. 1 (2004): 03–11. http://dx.doi.org/10.1017/s1357729800053789.

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AbstractWith an increase in the number of candidate genes for important traits in livestock, effective strategies for incorporating such genes into selection programmes are increasingly important. Those strategies in part depend on the frequency of a favoured allele in a population. Since comprehensive genotyping of a population is seldom possible, we investigate the consequences of sampling strategies on the reliability of the gene frequency estimate for a bi-allelic locus. Even within a subpopulation or line, often only a proportion of individuals will be genotype tested. However, through se
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Kiemeney, L., D. Timothy Bishop, DouglasF Easton, and Nicholas Hayward. "Frequency of familial melanoma and MLM2 gene." Lancet 345, no. 8949 (1995): 581–82. http://dx.doi.org/10.1016/s0140-6736(95)90489-1.

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Dickinson, Paul, Wendy L. Kimber, Fiona M. Kilanowski, Barbara J. Stevenson, David J. Porteous, and Julia R. Dorin. "High frequency gene targeting using insertional vectors." Human Molecular Genetics 2, no. 8 (1993): 1299–302. http://dx.doi.org/10.1093/hmg/2.8.1299.

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Thomas, Alun. "Accelerated Gene Counting for Haplotype Frequency Estimation." Annals of Human Genetics 67, no. 6 (2003): 608–12. http://dx.doi.org/10.1046/j.1529-8817.2003.00054.x.

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Dissertations / Theses on the topic "Gene frequency"

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Wilson, Iain. "Factors influencing gene frequency distributions in Cepaea nemoralis." Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335361.

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Dominguez-Bendala, Juan. "Manipulation of gene targeting frequency in mammalian cells." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/13678.

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With the development of nuclear transfer from somatic cells in several species, gene targeting can now be utilised for the design of more accurate animal models for human diseases and the generation of genetically modified livestock. However, its use is limited by the low frequency of homologous recombination in somatic cells. Future applications of gene targeting, such as the development of human gene therapies, will also require dramatic improvements in the efficiency of homologus recombination. The aim of this work has been devise strategies for the stimulation of gene targeting efficiency
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Xie, Yan. "STOCHASTIC DYNAMICS OF GENE TRANSCRIPTION." UKnowledge, 2011. http://uknowledge.uky.edu/statistics_etds/2.

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Gene transcription in individual living cells is inevitably a stochastic and dynamic process. Little is known about how cells and organisms learn to balance the fidelity of transcriptional control and the stochasticity of transcription dynamics. In an effort to elucidate the contribution of environmental signals to this intricate balance, a Three State Model was recently proposed, and the transcription system was assumed to transit among three different functional states randomly. In this work, we employ this model to demonstrate how the stochastic dynamics of gene transcription can be charact
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McArthur, James G. "Genetic elements which increase the frequency of gene amplification." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74313.

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Members of the HSAG family of mammalian genomic elements were subcloned into the pSV2-DHFR expression vector and shown to encourage vector amplification in cis when transfected into a variety of cell lines. The interaction of multiple positive acting elements was required for this effect, with the native configuration of these elements in HSAG-1 producing the greatest effect. These positive acting elements; purine-pyrimidine tracts, Alu-like repetitive elements, stem-loop structures, and A+T rich sequences, have been previously associated with "hotspots" for recombination. Analysis of the stru
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Li, Juan. "Molecular characterization of chicken repetitive DNA sequences." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B42577287.

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Li, Juan, and 李娟. "Molecular characterization of chicken repetitive DNA sequences." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B42577287.

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Gradinger, Abigail. "Atypical methylmalonic aciduria : frequency of mutations in the methylmalonyl-CoA epimerase (MCEE) gene." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101848.

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Methylmalonic aciduria results from defects in the enzyme methylmalonyl-CoA mutase and from defects in the synthesis of the enzyme's cofactor adenosylcobalamin. Two patients who excrete methylmalonic acid have been shown to have a homozygous nonsense mutation in the methylmalonyl-CoA epimerase gene (MCEE). To further understand the causes of methylmalonic acid excretion, the MCEE gene was sequenced in 229 patients who excreted methylmalonic acid for which no cause was known. Mutations were detected in five patients. Fusion of fibroblast lines from two patients with a homozygous nonsense mutati
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Trotter, Meridith V., and n/a. "Frequency-dependent selection and the maintenance of genetic variation." University of Otago. Department of Zoology, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081114.120926.

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Frequency-dependent selection has long been a popular heuristic explanation for the maintenance of genetic diversity in natural populations. Indeed, a large body of theoretical and empirical work has already gone into elucidating the causes and consequences of frequency-dependent selection. Most theoretical work, to date, has focused either on the diallelic case, or dealt with only very specific forms of frequency-dependence. A general model of the maintenance of multiallelic genetic diversity has been lacking. Here we extend a flexible general model of frequency-dependent selection, the pairw
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Credidio, Laura 1976. "Polimorfismo C936T do gene VEGF no risco de adenocarcinoma colorretal esporádico e em seus aspectos clínicos e biológicos." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308755.

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Orientadores: Claudio Saddy Rodrigues Coy, Carmen Silvia Passos Lima<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-20T01:34:06Z (GMT). No. of bitstreams: 1 Credidio_Laura_M.pdf: 7330672 bytes, checksum: 03e0aafb86a0b4df9c88c89f064490e2 (MD5) Previous issue date: 2012<br>Resumo: O papel da angiogênese para o desenvolvimento do câncer colorretal (CCR) ainda não é totalmente conhecido. Uma das principais glicoproteínas responsáveis pela angiogênese é o fator de crescimento endotelial vascular (VEGF), acredita-
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Millar, Anna L. "Frequency estimation of endometrial cancer associated with microsatellite instability and mismatch repair gene defects." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0005/MQ46045.pdf.

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Books on the topic "Gene frequency"

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Roychoudhury, Arun K. Human polymorphic genes: World distribution. Oxford University Press, 1988.

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Masatoshi, Nei, ed. Humanpolymorphic genes. Oxford University Press, 1988.

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Weir, B. S. Genetic data analysis II: Methods for discrete population genetic data. Sinauer Associates, 1996.

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Millar, Anna L. Frequency estimation of endometrial cancer associated with microsatellite instability and mismatch repair gene defects. National Library of Canada, 1999.

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C, Clarke B., Partridge Linda, and Royal Society (Great Britain), eds. Frequency-dependent selection: Proceedings of Royal Society discussion meeting held on 24 and 25 June 1987. Royal Society, 1988.

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Royal Society (Great Britain). Discussion Meeting. Frequency-dependent selection: Proceedings of a Royal Society Discussion Meeting held on 24 and 25 June 1987. The Society, 1988.

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Metin, Akay, and IEEE Engineering in Medicine and Biology Society., eds. Time frequency and wavelets in biomedical signal processing. IEEE Press, 1998.

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Genetic Data Analysis 2: Methods for Discrete Population Genetic Data. 2nd ed. Sinauer Associates, 1996.

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Clarke, B. C., and Linda Partridge. Frequency-dependent Selection. The Royal Society, 1988.

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Hughes, Gene. Gene Hughes Police Call Frequency Guide: Codes, Maps, Trunking. United States Radio Data, 1988.

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Book chapters on the topic "Gene frequency"

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Cook, L. M., and R. S. Callow. "Gene frequency." In Genetic and Evolutionary Diversity. Garland Science, 2023. http://dx.doi.org/10.1201/9781003421887-9.

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Ranjan, Shovit, and Akash Gautam. "Gene Frequency." In Encyclopedia of Animal Cognition and Behavior. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-47829-6_31-1.

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Ranjan, Shovit, and Akash Gautam. "Gene Frequency." In Encyclopedia of Animal Cognition and Behavior. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-319-55065-7_31.

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Rahman, Md Abdur, Madhu Chetty, Dieter Bulach, and Pramod P. Wangikar. "Frequency Decomposition Based Gene Clustering." In Neural Information Processing. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-26535-3_20.

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Liu, Yong-Bo, and Xin-Yu Wang. "Gene flow mitigation by ecological approaches." In Gene flow: monitoring, modeling and mitigation. CABI, 2021. http://dx.doi.org/10.1079/9781789247480.0009.

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Abstract With an increased area of cultivating genetically modified (GM) plants worldwide, the ecological risks of transgenic plants released into the environment have caused concern. One of the risks is the occurrence of gene flow between GM plants and non-GM plants, including their wild relatives. Gene flow data from oilseed rape (Brassica napus), cotton (Gossypium hirsutum), maize (Zea mays), soybean (Glycine max), rice (Oryza sativa), and wheat (Triticum aestivum) indicate that the frequency of pollen-mediated gene flow is negatively related with distance between donor and recipient plants
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Manly, Bryan F. J. "Gene frequency changes at a single genetic locus." In The Statistics of Natural Selection on Animal Populations. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4840-2_8.

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Trethowan, R. M., R. J. Pena, and M. Van Ginkel. "Breeding for Grain Quality: A Manipulation of Gene Frequency." In Wheat in a Global Environment. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-017-3674-9_32.

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McLysaght, Aoife, Cathal Seoighe, and Kenneth H. Wolfe. "High Frequency of Inversions During Eukaryote Gene Order Evolution." In Comparative Genomics. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-011-4309-7_6.

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Feeney, Ann J. "Genetic and Epigenetic Control of V Gene Rearrangement Frequency." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0296-2_6.

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Shumei, Li, Luo Xiaoting, Zeng Xiangyun, Hu Liqun, Xiong Liang, and Li Sisi. "Mutation Frequency of IMPDH1 Gene of Han Population in Ganzhou City." In Retinal Degenerative Diseases. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1399-9_33.

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Conference papers on the topic "Gene frequency"

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Tsitsos, Fotios, Alec Batts, Daniella Jimenez, et al. "Non-Invasive Gene Delivery to Brain Lymphatic System Using an Imaging Phased Array and Ultra-Short Focused Ultrasound Pulses." In 2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS). IEEE, 2024. https://doi.org/10.1109/uffc-js60046.2024.10794044.

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Dev, Ishaan, Anuj Baskota, Mikhail Shapiro, and Amit Lal. "Combining gas vesicle acoustic contrast agents with field-deployable GHz frequency ultrasonic chips to detect gene expression in sentinel microorganisms." In 2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS). IEEE, 2024. https://doi.org/10.1109/uffc-js60046.2024.10793589.

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Haga, A., G. Endo, and K. Kobayashi. "Evaluate Damage in DNA Molecules Caused by Intermediate Frequency Magnetic Fields Using Bacterial Gene Expression System for Mutation Repairing." In 2006_EMC-Europe_Barcelona. IEEE, 2006. https://doi.org/10.23919/emc.2006.10813278.

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K. Alkhudhairy, Miaad, та Elhassan Benyagoub. "Frequency of Genes Mediated β-lactams Resistance in Acinetobacter Baumannii Isolates from Iraq". У X INTERNATIONAL CONGRESS OF PURE AND APPLIED TECHNOLOGICAL SCIENCES. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress10-2.

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Background: Acinetobacter baumannii is a nosocomial virulent microorganism that can cause acute and chronic infections in burn patients. The aim of the study: Diagnosis of genes mediated β-lactams resistance among test isolates. Materials and Methods: 649 swabs collected from inpatients with burn-wound infections at a burn center in Al-Najaf Province/ Iraq, from August 2022 to February 2023. Results: 68/ 649 (10.5%) isolates of Acinetobacter baumannii were identified according to microscopically, cultural, and biochemical features. 22 (32.4%) isolates were found able to produce extended-spectr
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Yazdani, Somaie, and Ghosheh Abed Hodtani. "Frequency domain discovery of gene regulatory networks." In 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2015. http://dx.doi.org/10.1109/bibm.2015.7359848.

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Trinh, Thanh, DingMing Wu, Salman Salloum, Tung Nguyen, and Joshua Zhexue Huang. "A frequency-based gene selection method with random forests for gene data analysis." In 2016 IEEE RIVF International Conference on Computing & Communication Technologies, Research, Innovation, and Vision for the Future (RIVF). IEEE, 2016. http://dx.doi.org/10.1109/rivf.2016.7800293.

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Zaitseva, A. O., and M. O. Aksenov. "THE ROLE OF THE HIF1A GENE IN THE DEVELOPMENT OF ENDURANCE ATHLETES." In Х Всероссийская научно-практическая конференция. Nizhnevartovsk State University, 2021. http://dx.doi.org/10.36906/fks-2020/16.

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The sports phenotype is extremely complex, it includes a huge number of factors that depend on a combination of various traits and characteristics. The article contains information on one of the important genes involved in the adaptation of the body to hypoxia, which occurs during high-intensity aerobic loads. An analysis of the Ensemble electronic resource is presented, during which the frequency of occurrence of the HIF1A gene polymorphism was determined in various population groups. The results of the study of sports training of athletes, specializing in middle distance running, are shown.
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Shikata, Tetsuo, Toshihiko Shiraishi, Kumiko Tanaka, Shin Morishita, and Ryohei Takeuchi. "Effects of Acceleration Amplitude and Frequency of Mechanical Vibration on Osteoblast-Like Cells." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-41797.

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Bone formation is subject in vivo to mechanical stimulation. Although many researches for bone cells of osteoblastic lineage sensing and responding to mechanical stimulation have been reported mainly in the biochemical field, effects of mechanical stimulation on bone cells are not well understood. In this study, in order to clarify effects of acceleration amplitude and frequency of mechanical stimulation on MC3T3-E1, which is an osteoblast-like cell line derived from mouse calvaria, in the sense of mechanical vibrations, their cell proliferation, cell morphology, bone matrix generation and gen
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Matsumoto, Kazuko, Tokuzo Arao, Tetsuya Hamaguchi, et al. "Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5.

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Gouvea, Maury M., and Aluizio F. R. Araujo. "Population dynamics model for gene frequency prediction in evolutionary algorithms." In 2008 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2008. http://dx.doi.org/10.1109/cec.2008.4631006.

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Reports on the topic "Gene frequency"

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Tseng, Charles C. Equipment for High Frequency Measurements for Gene Expression Studies. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada413205.

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Jett, J. Pre-thymic somatic mutation leads to high mutant frequency at hypoxanthine-guanine phosphoribosyltransferase gene. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/98640.

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Morin, S., L. L. Walling, Peter W. Atkinson, J. Li, and B. E. Tabashnik. ets for CRISPR/Cas9-mediated gene drive in Bemisia tabaci. United States-Israel Binational Agricultural Research and Development Fund, 2021. http://dx.doi.org/10.32747/2021.8134170.bard.

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The goal of our BARD proposal was to build both the necessary infrastructure and knowledge for using the CRISPR/Cas9-based gene drive system to control the whitefly Bemisia tabaci. Our research focused on achieving three main goals: (1) establishing a CRISPR/Cas9 gene-editing system for producing genetically-edited B. tabaci; (2) generating and testing CRISPR/Cas9-mediated mutations targeting genes that represent two gene drive strategies: population replacement and population suppression; (3) using computer modeling to optimize strategies for applying CRISPR/Cas9 to control B. tabaci populati
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Weller, Joel I., Harris A. Lewin, and Micha Ron. Determination of Allele Frequencies for Quantitative Trait Loci in Commercial Animal Populations. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7586473.bard.

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Individual loci affecting economic traits in dairy cattle (ETL) have been detected via linkage to genetic markers by application of the granddaughter design in the US population and the daughter design in the Israeli population. From these analyses it is not possible to determine allelic frequencies in the population at large, or whether the same alleles are segregating in different families. We proposed to answer this question by application of the "modified granddaughter design", in which granddaughters with a common maternal grandsire are both genotyped and analyzed for the economic traits.
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Watad, Abed A., Paul Michael Hasegawa, Ray A. Bressan, Alexander Vainstein, and Yigal Elad. Osmotin and Osmotin-Like Proteins as a Novel Source for Phytopathogenic Fungal Resistance in Transgenic Carnation and Tomato Plants. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7573992.bard.

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The goal of this project is to enhance fungal resistance of carnation and tomato through the ectopic expression of osmotin and other pathogenesis-related (PR) proteins. The research objectives were to evaluate in vitro antifungal activity of osmotin and osmotin and other PR protein combinations against phytopathogens (including Fusarium oxysporum, Verticillium dahliae, Botrytus cinerea or Phytophthora infestans), develop protocols for efficient transformation of carnation and tomato, express PR proteins in transgenic carnation and tomato and evaluate fungal resistance of transgenic plants. Pro
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Sittipraneed, Siriporn. การศึกษาการแพร่กระจายของประชากรผึ้งโพรง Apis cerana กลุ่มตอนเหนือและตอนใต้ในบริเวณพื้นที่รอยต่อโดยใช้ดีเอ็นเอเครื่องหมาย : รายงานผลการวิจัย. Chulalongkorn University, 2002. https://doi.org/10.58837/chula.res.2002.30.

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PCR-RFLP of three mtDNA regions ( srRNA gene ,irRNA gene and intergenic COI – COII region) were used to investigated the distribution of northern and southern Apis cerana populations of 89 colonies from Prachuap Khiri Khan and Chumphon provinces. Three, four and eight haplotypes were obtained from DraI digestion of PCR-amplified 410 bp srRNA gene, 755bp IrRNA gene and 1710 bp intergenic COI-COII region,respectively. These three mtDNA regions generated 11 composit haplotypes. Twelve composite haplotypes were generated when samples from Yunnan and Hanoi were included. A UPGMA phenogram based on
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ZHOU, YUHUI, XIAOXIA MA, and JINGLAN SUN. Update on the Relationship Between the SLC4A7 variant rs4973768 and Breast Cancer risk: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0013.

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Review question / Objective: The aim of this meta-analysis was to get an updated opinion, which was about the role of the single nucleotide polymorphism (SNP) rs4973768 in the SLC4A7 gene played in the incident of breast cancer. Eligibility criteria: The included criteria were formulated for this meta-analysis as following:(1) studies with both case and control groups;(2) studies assessing the relation between the SLC4A7 rs4973768 polymorphism and sensibility to breast cancer;(3) studies with sufficient information such as genotype frequency for results of odds ratios (ORs) and 95% confidence
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Wongpiyabovorn, Jongkonnee, Nattiya Hirankarn, Yingyos Avihingsanon, Tewin Tencomnao, Yong Poovorawan, and Kriangsak Ruchusatsawat. The association between immunogenetics and genetic susceptibility of psoriasis in Thai population. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.27.

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Psoriasis is T-cell-mediated skin autoimmunity, required environmental triggers and genetic susceptibility factors to become manifested. Psoriasis is a chronic skin disease characterized by the abnormal hyperproliferation and differentiation of the epidermis, elongated and prominent blood vessels and a thick perivascular lymphocytic infiltrate. Vascular endothelial growth factor (VEGF) gene play important role in pathogenesis of various diseases with angiogenic basis such as breast cancer and autoimmune disease including psoriasis. Many studies analyzed the association of VEGF gene polymorphis
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Treadwell, Jonathan R., Mingche Wu, and Amy Y. Tsou. Management of Infantile Epilepsies. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepccer252.

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Objectives. Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may be associated with substantial developmental, behavioral, and psychological impairments. We evaluated the effectiveness, comparative effectiveness, and harms of pharmacologic, dietary, surgical, neuromodulation, and gene therapy treatments for infantile epilepsies. Data sources. We searched Embase®, MEDLINE®, PubMed®, the Cochrane Library, and gray literature for studies published from January 1, 1999, to August 19, 2021. Review methods. Using standard Evidence-based Practice Center me
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Ritprajak, Patcharee, Teerawut Nedumpun, and Sanipa Suradhat. Generation of in vitro porcine monocyte-derived dendritic cells (MoDcs) by new modified protocol. Faculty of Dentistry, Chulalongkorn University, 2016. https://doi.org/10.58837/chula.res.2016.18.

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Abstract:
The derivation of dendritic cells (Des) in vitro is an alternative system to overcome the low frequency of primary DCs and the difficulty of isolation techniques for study of DC immunobiology. To date, conventional culture protocol of porcine monocyte-derived DCs (MoDCs) has been widely used. However, this protocol is sometimes not practical due to the requirement of substantial monocyte number from the blood sample, and the process often interferes with DC maturation. To improve the protocol for porcine MoDC generation, we altered the previous conventional protocol, based on the human MoDC an
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