Academic literature on the topic 'Gene-targeted therapy'

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Journal articles on the topic "Gene-targeted therapy"

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Hart, I. R., and R. G. Vile. "Targeted gene therapy." British Medical Bulletin 51, no. 3 (1995): 647–55. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072984.

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Katz, Stephen I. "Prospects for targeted gene therapy." Clinical and Experimental Dermatology 25, no. 2 (2000): 157. http://dx.doi.org/10.1046/j.1365-2230.2000.0604c.x.

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Miller, Nicholas, and Richard Vile. "Targeted vectors for gene therapy." FASEB Journal 9, no. 2 (1995): 190–99. http://dx.doi.org/10.1096/fasebj.9.2.7781922.

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Harris, Jonathan D., and Nick R. Lemoine. "Strategies for targeted gene therapy." Trends in Genetics 12, no. 10 (1996): 400–405. http://dx.doi.org/10.1016/0168-9525(96)40031-2.

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Dougherty, Graeme J., Peter D. Davis, and Shona T. Dougherty. "Vascular-targeted cancer gene therapy." Expert Opinion on Biological Therapy 4, no. 12 (2004): 1911–20. http://dx.doi.org/10.1517/14712598.4.12.1911.

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Węgrzyn, Alicja. "Gene expression-targeted isoflavone therapy." IUBMB Life 64, no. 4 (2012): 307–15. http://dx.doi.org/10.1002/iub.1007.

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Parekh-Olmedo, H., L. Ferrara, E. Brachman, and E. B. Kmiec. "Gene therapy progress and prospects: targeted gene repair." Gene Therapy 12, no. 8 (2005): 639–46. http://dx.doi.org/10.1038/sj.gt.3302511.

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Rots, M. G., D. T. Curiel, W. R. Gerritsen, and H. J. Haisma. "Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors." Journal of Controlled Release 87, no. 1-3 (2003): 159–65. http://dx.doi.org/10.1016/s0168-3659(02)00360-7.

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KONISHI, Hiroyasu, and Tetsuichiro MUTO. "Targeted Gene Therapy for Colorectal Cancer." Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons) 24, no. 1 (1999): 1–7. http://dx.doi.org/10.4030/jjcs1979.24.1_1.

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Rocconi, Rodney, T. Numnum, Mariam Stoff-Khalili, Sharmila Makhija, Ronald Alvarez, and David Curiel. "Targeted Gene Therapy for Ovarian Cancer." Current Gene Therapy 5, no. 6 (2005): 643–53. http://dx.doi.org/10.2174/156652305774964668.

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Dissertations / Theses on the topic "Gene-targeted therapy"

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Harris, Jonathan David. "Targeted gene therapy for cancer." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309239.

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Samani, Amir Abbas. "IGF-IR targeted cancer gene therapy." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18206.

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Since the declaration of “War on cancer” in 1971, and with the insight provided by recent advances in human genetics and in molecular technology , the field of cancer biology has been expanded rapidly providing hope that a cure for this lethal disease will be found. One of the major contributions of the field of cell biology to the understanding of malignant diseases has been the identification of growth factors and their receptors as major promoters of transformation and malignant progression. In particular, the appreciation of the central role that receptor tyrosine kinases (RTK) play in d
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Mckiver, Bryan D. "SND1-Targeted Gene Therapy for Hepatocellular Carcinoma." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5676.

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Staphylococcal nuclease and tudor-domain containing 1 (SND1) is an oncogene for a wide variety of cancers, including hepatocellular carcinoma (HCC). SND1 is a multifunctional protein regulating gene expression of proto-oncogenes and tumor suppressor genes, making SND1 a prime target for developing cancer therapeutics. This notion is especially attributed to HCC as most patients are diagnosed in advanced stages and the therapeutic options available for these patients are severely limited. In this study, we evaluated the therapeutic potential of a replication-defective adenovirus vector deliveri
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Sabine, Victoria Saranne. "Targeted gene therapy for canine osteosarcoma : preliminary investigations." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1642/.

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Osteosarcoma (OS) is the most common bone cancer in dogs. It is biologically aggressive and <20% survive >2 years with standard therapy. Hence, new approaches must be considered. TP53 is altered in ~50% of human and canine cancers, including OS, making it a candidate for targeted suicide gene therapy strategies. Canine OS is considered to be a good model for human OS. The aims of this study were to:  examine the site incidence of canine OS retrieved from Glasgow University Veterinary School (GUVS) histology database;  perform TP53 mutational analysis in canine OS cases diagnosed at GUVS;  i
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Shaw, James Alistair MacGregor. "Towards muscle-targeted gene therapy for diabetes mellitus." Thesis, University of Aberdeen, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325232.

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Diaz, Marcano Rosa Maria. "Viral vectors for targeted gene therapy of cancer." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267735.

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Monfort, Dagmara Anne. "Recombinant Elastin Based Nanoparticles for Targeted Gene Therapy." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6627.

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Gene therapy is a technique used to inactivate, replace or insert a corrective copy of a defective gene in order to help diseased tissues to function properly. Gene therapy is a promising treatment for many diseases cancer, cystic fibrosis, and Parkinson’s. There are different methods to introduce a gene to the cell; one of them is the use of viruses. Among viruses, lentiviruses have been popular vectors for gene delivery due to their efficient mode of gene delivery. However, the non-specific delivery of genes associated with viruses may result in undesirable side effects. Here, we propose a h
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Taylor, Sarah Louise. "Development of an ultrasound-targeted retroviral gene therapy vector." Thesis, Institute of Cancer Research (University Of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436328.

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Denby, Laura. "Development of targeted gene therapy vectors for cardiovascular disease." Thesis, University of Glasgow, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422499.

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Jackson, Laura. "Oxygen-regulated gene expression in Escherichia coli and hypoxia-targeted gene therapy." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414676.

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Books on the topic "Gene-targeted therapy"

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Lao, Yeh-Hsing. Nanosystems for Gene Editing and Targeted Therapy. [publisher not identified], 2019.

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Ward, Christopher Michael. Development of folate-targeted non-viral vectors for systemic cancer gene therapy. University of Birmingham, 2000.

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Bo, Xuenong, and Joost Verhaagen. Gene delivery and therapy for neurological disorders. Humana Press, 2015.

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Houghton, Peter J., and Robert Arceci. Molecularly targeted therapy for childhood cancer. Springer, 2010.

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Slabý, Ondřej. MicroRNAs in solid cancer: From biomarkers to therapeutic targets. Nova Science, 2011.

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Kahn, Michael. Targeting the Wnt pathway in cancer. Springer, 2011.

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N, Syrigos Konstantinos, and Harrington Kevin J. 1958-, eds. Targeted therapy for cancer. Oxford University Press, 2003.

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Williams, Sophie I., and Christopher E. Rogers. HER2 and cancer: Mechanism, testing, and targeted therapy. Nova Biomedical Books, 2011.

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W, Siemann Dietmar, ed. Vascular-targeted therapies in oncology. J. Wiley, 2006.

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Biotargets Of Cancer In Current Clinical Practice. Humana Press, 2012.

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Book chapters on the topic "Gene-targeted therapy"

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Hart, I. R. "Transcriptionally Targeted Gene Therapy." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80071-9_2.

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Mohammad, Akheel, and Ashmi Wadhwania. "Targeted Therapy, Immunotherapy, and Gene Therapy." In Head and Neck Oncology. CRC Press, 2021. http://dx.doi.org/10.1201/9780367822019-23.

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R., Catherine, O’ Riordan, and Antonius Song. "PEGylated Adenovirus for Targeted Gene Therapy." In Gene Therapy Protocols. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-248-3_9.

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Wu, Hongju, and David T. Curiel. "Fiber-modified Adenoviruses for Targeted Gene Therapy." In Gene Therapy Protocols. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-248-3_8.

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Shen, Fanxia, and Hua Su. "Targeted Gene Therapy for Ischemic Stroke." In Neuromethods. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2306-9_8.

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de Gruijl, Tanja D., Herbert M. Pinedo, and Rik J. Scheper. "Immunotherapy of Cancer by Dendritic Cell-Targeted Gene Transfer." In Cancer Gene Therapy. Humana Press, 2005. http://dx.doi.org/10.1007/978-1-59259-785-7_10.

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Alsaggar, Mohammad, and Dexi Liu. "Liver-Targeted Gene and Cell Therapies: An Overview." In Gene Therapy and Cell Therapy Through the Liver. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55666-4_1.

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Dougherty, Graeme J., Peter D. Davis, and Shona T. Dougherty. "Development of Vasculature-targeted Cancer Gene Therapy." In Vascular-Targeted Therapies in Oncology. John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470035439.ch14.

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Jia, Li-Jun, and Zi-Chun Hua. "Development of Bacterial Vectors for Tumor-Targeted Gene Therapy." In Gene Therapy of Cancer. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-561-9_7.

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Bilbao, G., J. Gómez-Navarro, and David T. Curiel. "Targeted Adenoviral Vectors for Cancer Gene Therapy." In Advances in Experimental Medicine and Biology. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5357-1_57.

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Conference papers on the topic "Gene-targeted therapy"

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Kusumanchi, Praveen, Yonghua Zhang, Padma Chakka, et al. "Abstract 1506: Prodrug targeted gene therapy for colorectal cancer." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1506.

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Noble, Misty L., Shuxian Song, Ryan R. Sun, et al. "Improved luciferase gene expression using ultrasound targeted microbubble destruction therapy in swine." In 12TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND. AIP, 2012. http://dx.doi.org/10.1063/1.4769917.

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Rezzoug, Francine, Shelia D. Thomas, Segen Tella, and Donald M. Miller. "Abstract 1522: Targeted gene therapy · c-MYC and hTERT in the scope." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1522.

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Zhang, Fan, Miacheal E. Coon, Neha N. Parayath, Sirrka B. Stephan, Smitha P. Pillai, and Matthias T. Stephan. "Abstract 4770: Programming tumor-clearing macrophages with targeted in situ gene therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4770.

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Zhang, Fan, Miacheal E. Coon, Neha N. Parayath, Sirrka B. Stephan, Smitha P. Pillai, and Matthias T. Stephan. "Abstract 4770: Programming tumor-clearing macrophages with targeted in situ gene therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4770.

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Wilson, Ariel, Javier Mazzaferri, Éric Bergeron, et al. "In vivo laser targeted gene therapy of retina ganglion cells (Conference Presentation)." In Ophthalmic Technologies XXIX, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2019. http://dx.doi.org/10.1117/12.2509870.

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Duong, Connie, Cathy Chen, Sakiko Yoshida, et al. "Abstract 5423: Novel targeted therapy for neuroblastoma: Silencing the MXD3 gene using siRNA." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5423.

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Little, Annette S., Jessica Hunt, David Hughes, et al. "Abstract A148: Modeling patient responses to targeted therapy with rAAV mediated gene editing." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1535-7163.targ-13-a148.

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Phelps, Michael, Heechang Yang, and Eleanor Chen. "Abstract 5096: Targeted ablation of essential oncogenes in rhabdomyosarcoma with CRISPR/Cas9 gene therapy." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5096.

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Petrov, G. O., V. S. Mukhanov, and M. A. Dymova. "DEVELOPMENT M13 BACTERIOPHAGE-BASED TARGETED HYBRID VECTORS FOR HUMAN GLIOBLASTOMA CELL SELECTIVE TRANSDUCTION." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-357.

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Bacteriophages, bacterial viruses, are currently being used as source of effective gene therapy tools for cancer. The aim of this study was to develop targeted hybrid vectors based on filamentous phage M13, capable of efficient and selective delivery of transgenes into U-87 MG human glioblastoma cells.
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Reports on the topic "Gene-targeted therapy"

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Ponnazhagan, Selvarangan. Targeted Gene Therapy for Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427915.

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Kasahara, Noriyuki. Viroreplicative Gene Therapy Targeted to Prostate Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada538598.

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Von Seggern, Daniel J. Adenoviral Gene Therapy Vectors Targeted to Prostate Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada429389.

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VonSeggern, Daniel J. Adenoviral Gene Therapy Vectors Targeted to Prostate Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada417951.

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Krasnykh, Victor. Derivation of Targeted Phage Vectors for Gene Therapy of Prostate Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462846.

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Krasnykh, Victor. Derivation of Double-Targeted Adenovirus Vectors for Gene Therapy of Prostate Cancer. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada439290.

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Krasnykh, Victor. Derivation of Double-Targeted Adenovirus Vectors for Gene Therapy of Prostate Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada419820.

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Hatefi, Arash. Development of a Nature-Inspired Vector for Targeted Systemic Breast Cancer Gene Therapy. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada493871.

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Rogers, Buck E. Gene Therapy of Disseminated Breast Cancer Using Adenoviral Vectors Targeted Through Immunological Methods. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/adb244250.

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Wei, Fang. Multifunctional Virus-Nanoshell Assembly for Targeted Hyperthermia and Viral Gene Therapy for Breast Cancer. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada566649.

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