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Journal articles on the topic 'Gene-targeted therapy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Hart, I. R., and R. G. Vile. "Targeted gene therapy." British Medical Bulletin 51, no. 3 (1995): 647–55. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072984.

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2

Katz, Stephen I. "Prospects for targeted gene therapy." Clinical and Experimental Dermatology 25, no. 2 (2000): 157. http://dx.doi.org/10.1046/j.1365-2230.2000.0604c.x.

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3

Miller, Nicholas, and Richard Vile. "Targeted vectors for gene therapy." FASEB Journal 9, no. 2 (1995): 190–99. http://dx.doi.org/10.1096/fasebj.9.2.7781922.

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4

Harris, Jonathan D., and Nick R. Lemoine. "Strategies for targeted gene therapy." Trends in Genetics 12, no. 10 (1996): 400–405. http://dx.doi.org/10.1016/0168-9525(96)40031-2.

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5

Dougherty, Graeme J., Peter D. Davis, and Shona T. Dougherty. "Vascular-targeted cancer gene therapy." Expert Opinion on Biological Therapy 4, no. 12 (2004): 1911–20. http://dx.doi.org/10.1517/14712598.4.12.1911.

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6

Węgrzyn, Alicja. "Gene expression-targeted isoflavone therapy." IUBMB Life 64, no. 4 (2012): 307–15. http://dx.doi.org/10.1002/iub.1007.

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7

Parekh-Olmedo, H., L. Ferrara, E. Brachman, and E. B. Kmiec. "Gene therapy progress and prospects: targeted gene repair." Gene Therapy 12, no. 8 (2005): 639–46. http://dx.doi.org/10.1038/sj.gt.3302511.

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8

Rots, M. G., D. T. Curiel, W. R. Gerritsen, and H. J. Haisma. "Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors." Journal of Controlled Release 87, no. 1-3 (2003): 159–65. http://dx.doi.org/10.1016/s0168-3659(02)00360-7.

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9

KONISHI, Hiroyasu, and Tetsuichiro MUTO. "Targeted Gene Therapy for Colorectal Cancer." Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons) 24, no. 1 (1999): 1–7. http://dx.doi.org/10.4030/jjcs1979.24.1_1.

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10

Rocconi, Rodney, T. Numnum, Mariam Stoff-Khalili, Sharmila Makhija, Ronald Alvarez, and David Curiel. "Targeted Gene Therapy for Ovarian Cancer." Current Gene Therapy 5, no. 6 (2005): 643–53. http://dx.doi.org/10.2174/156652305774964668.

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11

Unger, E. C., and R. Sweitzer. "Ultrasound-targeted gene and drug therapy." Ultrasound in Medicine & Biology 29, no. 5 (2003): S41. http://dx.doi.org/10.1016/s0301-5629(03)00211-4.

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12

Shi, Qizhen. "Platelet-Targeted Gene Therapy for Hemophilia." Molecular Therapy - Methods & Clinical Development 9 (June 2018): 100–108. http://dx.doi.org/10.1016/j.omtm.2018.01.011.

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13

Colombo, Mario P., and Giorgio Parmiani. "Tumor-cell-targeted cytokine gene therapy." Immunology Today 12, no. 7 (1991): 249–50. http://dx.doi.org/10.1016/0167-5699(91)90044-t.

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14

Binley, Katie. "Exploiting hypoxia for targeted gene therapy." Gene Therapy and Regulation 2, no. 1 (2003): 59–75. http://dx.doi.org/10.1163/156855803762295431.

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15

Bachtarzi, Houria, Mark Stevenson, and Kerry Fisher. "Cancer gene therapy with targeted adenoviruses." Expert Opinion on Drug Delivery 5, no. 11 (2008): 1231–40. http://dx.doi.org/10.1517/17425240802507636.

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16

Weichselbaum, Ralph R., Dennis E. Hallahan, Vikas P. Sukhatme, and Donald W. Kufe. "Gene therapy targeted by ionizing radiation." International Journal of Radiation Oncology*Biology*Physics 24, no. 3 (1992): 565–67. http://dx.doi.org/10.1016/0360-3016(92)91075-x.

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17

Curiel, D. T. "TARGETED GENE DELIVERY TO ACCOMPLISH GENE THERAPY FOR CANCER." Journal of Immunotherapy 16, no. 3 (1994): 235. http://dx.doi.org/10.1097/00002371-199410000-00014.

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18

Cristiano, Richard J. "Targeted non-viral gene delivery for cancer gene therapy." Frontiers in Bioscience 3, no. 4 (1998): d1161–1170. http://dx.doi.org/10.2741/a352.

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19

Boggs, Sallie S. "Targeted gene modification for gene therapy of stem cells." International Journal of Cell Cloning 8, no. 2 (1990): 80–95. http://dx.doi.org/10.1002/stem.5530080202.

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20

Kim, Jayoung, David R. Wilson, Camila G. Zamboni, and Jordan J. Green. "Targeted polymeric nanoparticles for cancer gene therapy." Journal of Drug Targeting 23, no. 7-8 (2015): 627–41. http://dx.doi.org/10.3109/1061186x.2015.1048519.

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21

Davies, D. Mark. "Tuberous sclerosis: from gene to targeted therapy." Clinical Medicine 12, Suppl 6 (2012): s7—s10. http://dx.doi.org/10.7861/clinmedicine.12-6-s7.

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22

Altwaijry, Najla, Sukrut Somani, and Christine Dufès. "Targeted nonviral gene therapy in prostate cancer." International Journal of Nanomedicine Volume 13 (September 2018): 5753–67. http://dx.doi.org/10.2147/ijn.s139080.

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23

King, Gwendalyn, James Curtin, Marianela Candolfi, Kurt Kroeger, Pedro Lowenstein, and Maria Castro. "Gene Therapy and Targeted Toxins for Glioma." Current Gene Therapy 5, no. 6 (2005): 535–57. http://dx.doi.org/10.2174/156652305774964631.

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24

G. Castro, Maria, Marianela Candolfi, Kurt M. Kroeger, et al. "Gene Therapy and Targeted Toxins for Glioma." Current Gene Therapy 11, no. 3 (2011): 155–80. http://dx.doi.org/10.2174/156652311795684722.

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25

Li, L.-Y., H.-Y. Dai, F.-L. Yeh, et al. "Targeted hepatocellular carcinoma proapoptotic BikDD gene therapy." Oncogene 30, no. 15 (2010): 1773–83. http://dx.doi.org/10.1038/onc.2010.558.

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26

Alexander, J. J., and W. W. Hauswirth. "Prospects for retinal cone-targeted gene therapy." Drug News & Perspectives 21, no. 5 (2008): 267. http://dx.doi.org/10.1358/dnp.2008.21.5.1223972.

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27

Starling, Shimona. "Targeted aspartoacylase gene therapy reverts Canavan disease." Nature Reviews Neurology 14, no. 1 (2017): 4. http://dx.doi.org/10.1038/nrneurol.2017.170.

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28

Park, Kinam. "Cornea-targeted gene therapy using adenovirus vector." Journal of Controlled Release 181 (May 2014): 53. http://dx.doi.org/10.1016/j.jconrel.2014.03.042.

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29

Waehler, Reinhard, Stephen J. Russell, and David T. Curiel. "Engineering targeted viral vectors for gene therapy." Nature Reviews Genetics 8, no. 8 (2007): 573–87. http://dx.doi.org/10.1038/nrg2141.

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30

Zylberberg, C., K. Gaskill, S. Pasley, and S. Matosevic. "Engineering liposomal nanoparticles for targeted gene therapy." Gene Therapy 24, no. 8 (2017): 441–52. http://dx.doi.org/10.1038/gt.2017.41.

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31

Aravalli, Rajagopal N., John D. Belcher, and Clifford J. Steer. "Liver-targeted gene therapy: Approaches and challenges." Liver Transplantation 21, no. 6 (2015): 718–37. http://dx.doi.org/10.1002/lt.24122.

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32

Alexander, J. J., and W. W. Hauswirth. "Prospects for retinal cone-targeted gene therapy." Drug News & Perspectives 21, no. 5 (2008): 267. http://dx.doi.org/10.1358/dnp.2008.21.5.1219012.

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33

Dirven, Clemens M. F., Jacques Grill, Martine L. M. Lamfers, et al. "Gene therapy for meningioma: improved gene delivery with targeted adenoviruses." Journal of Neurosurgery 97, no. 2 (2002): 441–49. http://dx.doi.org/10.3171/jns.2002.97.2.0441.

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Object. Due to their surgical inaccessibility or aggressive behavior, some meningiomas cannot be cured with current treatment strategies. Gene therapy is an emerging strategy for the treatment of brain tumors, which the authors investigated to determine whether adenoviruses could be used for gene transfer in meningioma cells. Methods. The presence of the high-affinity Coxsackievirus and adenovirus receptor (CAR) for adenovirus type 5, as well as endothelial growth factor receptor (EGFR) and alphav integrins (ITGAVs), were analyzed in primary tumors by using immunohistochemical studies and in p

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34

Margarita, Shuvalova, and Shokhina Arina. "Specific Endothelial Promoters for Targeted Gene Expression and Gene Therapy." Research Journal of Biotechnology 20, no. 6 (2025): 157–64. https://doi.org/10.25303/206rjbt1570164.

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Tissue-specific promoters play a crucial role in both fundamental research and practical applications. They allow targeted gene expression only in specific cell types, minimizing off-target effects on neighboring cells. In the context of gene therapy for vascular diseases, the use of tissue-specific promoters becomes particularly important to minimize non-targeted transgene expression and potential side effects. Endothelial cells, which line blood vessels and regulate the exchange of substances between blood and organs, are potential targets for gene therapy in certain vascular diseases. Sever

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35

Liu, Jinlu, Ling Yang, Xin Yuan, et al. "Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma." International Journal of Nanomedicine Volume 16 (November 2021): 7697–709. http://dx.doi.org/10.2147/ijn.s331519.

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36

Pranjol, Md, and Amin Hajitou. "Bacteriophage-Derived Vectors for Targeted Cancer Gene Therapy." Viruses 7, no. 1 (2015): 268–84. http://dx.doi.org/10.3390/v7010268.

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37

Lin, X., L. Tao, and D. Tang. "Gene Therapy, A Targeted Treatment for Diabetic Nephropathy." Current Medicinal Chemistry 20, no. 30 (2013): 3774–84. http://dx.doi.org/10.2174/09298673113209990183.

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38

R. Dass, Mark A. Burton, Crispin. "Microsphere-Mediated Targeted Gene Therapy of Solid Tumors." Drug Delivery 6, no. 4 (1999): 243–52. http://dx.doi.org/10.1080/107175499266832.

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39

Cutrera, Jeffry, Denada Dibra, Arun Satelli, Xuexing Xia, and Shulin Li. "Intricacies for Posttranslational Tumor-Targeted Cytokine Gene Therapy." Mediators of Inflammation 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/378971.

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The safest and most effective cytokine therapies require the favorable accumulation of the cytokine in the tumor environment. While direct treatment into the neoplasm is ideal, systemic tumor-targeted therapies will be more feasible. Electroporation-mediated transfection of cytokine plasmid DNA including a tumor-targeting peptide-encoding sequence is one method for obtaining a tumor-targeted cytokine produced by the tumor-bearing patient’s tissues. Here, the impact on efficacy of the location of targeting peptide, choice of targeting peptide, tumor histotype, and cytokine utilization are studi

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40

Hawkins, RE, HA Whittington, SJ Watkins, and DE Gilham. "Antibodies: from genes to targeted cancer gene therapy." Gene Therapy 5, no. 12 (1998): 1581–83. http://dx.doi.org/10.1038/sj.gt.3300788.

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41

Mairs, Robert J., Natasha E. Fullerton, Emilio Cosimo, and Marie Boyd. "Gene manipulation to enhance MIBG-targeted radionuclide therapy." Nuclear Medicine and Biology 32, no. 7 (2005): 749–53. http://dx.doi.org/10.1016/j.nucmedbio.2005.03.011.

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42

Brown, M., M. Boyd, A. Livingston, R. Mairs, and D. Kirk. "Targeted gene therapy of prostate cancer cell lines." European Urology Supplements 2, no. 1 (2003): 221. http://dx.doi.org/10.1016/s1569-9056(03)80863-1.

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43

Monfort, D. A., and P. Koria. "Recombinant elastin-based nanoparticles for targeted gene therapy." Gene Therapy 24, no. 10 (2017): 610–20. http://dx.doi.org/10.1038/gt.2017.54.

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44

Tepper, Deborah E. "Calcitonin Gene-Related Peptide Targeted Therapy for Migraine." Headache: The Journal of Head and Face Pain 56, no. 2 (2016): 447–48. http://dx.doi.org/10.1111/head.12759.

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45

Ghali, Shadi, Marlese P. Dempsey, Deirdre M. Jones, Raymond H. Grogan, Peter E. Butler, and Geoffrey C. Gurtner. "Plastic Surgical Delivery Systems for Targeted Gene Therapy." Annals of Plastic Surgery 60, no. 3 (2008): 323–32. http://dx.doi.org/10.1097/sap.0b013e31806917b0.

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46

Mauro, Michael J., and Brian J. Druker. "STI571: A gene product-targeted therapy for leukemia." Current Oncology Reports 3, no. 3 (2001): 223–27. http://dx.doi.org/10.1007/s11912-001-0054-z.

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47

Moscoso, Carlos G., and Clifford J. Steer. "Liver targeted gene therapy: Insights into emerging therapies." Drug Discovery Today: Technologies 34 (December 2019): 9–19. http://dx.doi.org/10.1016/j.ddtec.2020.11.001.

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48

Nicola, Juan Pablo, and Christopher J. LaRocca. "Sodium iodide symporter-targeted gene therapy in glioblastoma." Molecular Therapy - Oncolytics 28 (March 2023): 44–45. http://dx.doi.org/10.1016/j.omto.2022.12.004.

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49

Dana Jones, Susan, and Wayne A. Marasco. "Antibodies for targeted gene therapy: extracellular gene targeting and intracellular expression." Advanced Drug Delivery Reviews 31, no. 1-2 (1998): 153–70. http://dx.doi.org/10.1016/s0169-409x(97)00099-9.

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50

Tian, Peikun, Shengjun Ren, Changchun Ren, et al. "A novel receptor-targeted gene delivery system for cancer gene therapy." Science in China Series C: Life Sciences 42, no. 2 (1999): 216–24. http://dx.doi.org/10.1007/bf02880059.

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