Relevant bibliographies by topics / Generic Drugs Market

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Generic Drugs Market'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Generic Drugs Market"

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Nazmus, Saqueeb. "MARKET RESEARCH ON POPULAR ANTIHYPERTENSIVE DRUGS." DIU Journal of Health and Life Sciences 2, no. 01 & 02 (2024): 39–43. http://dx.doi.org/10.36481/diujhls.v01i1.5f6ak424.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate),Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazidine Hydrochloride), Ramace (Generic
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Saqueeb, Nazmus. "Market Research On Popular Antihypertensive Drugs." DIU Journal of Allied Health Sciences 2, no. 01 & 02 (2024): 39–43. https://doi.org/10.36481/diujahs.v01i1.5f6ak424.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate),Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazidine Hydrochloride), Ramace (Generic
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Nazmus, Saqueeb and Shakil Ahmed. "Market research on Popular Antihypertensive Drugs." DIU Journal of Health and Life Sciences 2, no. 1 & 2 (2015): 39–43. https://doi.org/10.5281/zenodo.11076990.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate), Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazi
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Jang, Suhyun, and Sunmee Jang. "Trends in Pharmaceutical Market Structure and Generic Drug Utilization in the Korean National Health Security System (2007-2017)." Yakhak Hoeji 67, no. 3 (2023): 205–13. http://dx.doi.org/10.17480/psk.2023.67.3.205.

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We aimed to analyze the market structure and changes in the market share of new drugs, original drugs, and generic drugs in the pharmaceutical market over the past ten years. We utilized national health insurance claims data, including both national health insurance and medical aid, from 2007 to 2017 to establish pharmaceutical expenditure and usage data. The drugs are categorized into new drugs, original drugs (expired patents), and generic drugs. Furthermore, we classified the original drugs as single-source and multi-source original drugs based on whether generic drugs had entered the marke
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Konuri, Dinesh Chandra, Mamillapalli S., A. Elphine P., and Brahma S. R. Desu. "COMPARATIVE STUDY OF REGULATORY REQUIREMENTS AND REGISTRATION PROCESS OF GENERIC DRUGS IN JAPAN AND CHINA." International Journal of Drug Regulatory Affairs 3, no. 1 (2018): 75–87. http://dx.doi.org/10.22270/ijdra.v3i1.159.

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A Generic Product must meet the standards established by Pharmaceutical Medical Device Agency (PMDA) & China Food and Drug Administration (CFDA) to be approved for marketing in Japan and China respectively. This study covers the introduction to generic drugs, and JAPAN & CHINA regulatory authorities. It also includes the requirements and registration of Generic Drugs in above specified countries. It also includes the checklist for comparative study of regulatory requirements and registration process of generic drugs in JAPAN & CHINA.
 JAPAN and CHINA are two different markets
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Kuveria, Helly, Zuki Patel, Manvendra Raval, and Maitreyi Zaveri. "Overview and Lifecycle Management of Generic Pharmaceutical Drugs in Mexico, Guatemala and Brazil." International Journal of Drug Regulatory Affairs 12, no. 2 (2024): 65–72. http://dx.doi.org/10.22270/ijdra.v12i2.676.

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Objective: The generic pharmaceutical markets in Mexico, Guatemala, and Brazil are influenced by distinct regulatory frameworks, production and distribution dynamics, and marketing strategies, which shape lifecycle management. Regulatory policies, market competition, and healthcare initiatives impact accessibility, affordability, and quality, presenting both challenges and opportunities for enhancement in these areas. Summary: This thesis offers an in-depth examination of lifecycle management strategies in the generic pharmaceutical markets of Mexico, Guatemala, and Brazil. Generic drugs are c
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Craddock, Kathleen. "Improving Generic Drug Approval at the FDA." Michigan Journal of Environmental & Administrative Law, no. 7.2 (2018): 421. http://dx.doi.org/10.36640/mjeal.7.2.improving.

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Generic drugs are the store-brand cereal of the drug world. While they lack the vibrant colors of and exciting commercials behind name brands, generics are still effective. Most importantly, for some people, they make the difference between accessing essential treatment and going without. Getting generics to market as quickly as possible means fewer people will cut pills in half or skip doses to save money, which also saves billions of dollars across the U.S. health system. Because a new generic does not offer lifesaving changes for people with rare or complicated diseases, generics lack the “
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Samson, Marvin. "Generic injectable drugs: From idea to market." American Journal of Health-System Pharmacy 60, no. 11 (2003): 1117–22. http://dx.doi.org/10.1093/ajhp/60.11.1117.

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Masuda, Sachiko. "The trend in patent infringement litigation against generic drugs or biosimilars in Japan." Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector 15, no. 1 (2019): 10–17. http://dx.doi.org/10.1177/1741134319826338.

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The timing of market entry for generic drugs or biosimilars based on patent expiration is not always clear for producers of generic drugs and biosimilars or brand-name drug companies, because of an uncertainty due to patent infringement, the market environment, and legislation. In Japan, the policy of promoting the use of generic drugs began in the early 2000s, and the government’s target for generic drug use rate is 80% by 2020. In addition to this drastic change in the market environment, changes in legislation have complicated the timing of market entry for generic drugs and biosimilars. Al
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Bhavna, Chandnani*1 Vikram Pandya2 Chaudhari Komal3 Patel Bhoomi4 Kapadia Krishna5 Sheikh Fiza6 Rajput Suraj6. "Research Article Quality Effectiveness Assessment Study On Diffrent Brands Of Paracetamol Tablet Available In Navsari Market." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 494–501. https://doi.org/10.5281/zenodo.10822739.

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Drugs are any substance either biological or chemical and when consumed affects the physiological function of the body. These drugs are classified as OTC drugs or Prescription drugs. Both OTC drugs and Prescription drugs are available as Generic drugs or Branded/Proprietary drugs. While Branded drugs are protected by a patent for a particular number of years, generic drugs are not. Generic drugs only have to meet the same bio-equivalence requirement as their branded counterparts. Also, Branded drugs take a lot of time to get approved while generic drugs take a much lesser time. Due to the time
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Dissertations / Theses on the topic "Generic Drugs Market"

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Rigestam, Björn. "Pharmaceutical patents and generic drugs : When may interim injunctions be issued against an attempt or preparation to offer generic drugs on the market?" Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Rättsvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-18933.

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Since the implementation of Directive 2004/48 EC on the Enforcement of Intellectual Property Rights in Sweden there is today a possibility for pharmaceutical companies holding a patent to issue interim injunctions against a generic company on the grounds of an attempt or preparation to a pharmaceutical patent infringement. It has been shown that one of the earliest steps in which a generic company may infringe a pharmaceutical patent is to offer the generic drugs onto the market. However, since the implementation of the attempt and preparation rule in the Swedish Patent Act questions have been
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Bredenkamp, Jhandre. "The effect of generic medicine competition on the market share growth and pricing of originator brand medicine in the South African private pharmaceutical market." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/21380.

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Thesis (MBA)--Stellenbosch University, 2011.<br>This study analyses the effects of generic medicine competition on the market share growth and pricing of originator brand medicine in the South African private pharmaceutical market. The study is based on five years (2005 to 2011) of IMS Health market share data for 39 originator brand drugs that have been exposed to competition from generic substitutes from 2001. The results show that, for all the drug molecules included in the study pooled together, the price of an originator brand medicine relative to the weighted average price of its generic
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Monteiro, Nilo Sergio Duarte. "O impacto das representaÃÃes de mÃdicos, farmacÃuticos e consumidores no uso dos medicamentos de marca e genÃricos." Universidade Federal do CearÃ, 2002. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7678.

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O presente trabalho investiga o impacto das representaÃÃes de mÃdicos, farmacÃuticos e consumidores no uso dos medicamentos de marca e genÃricos. Nesta construÃÃo buscou-se evidenciar as contradiÃÃes, crenÃas e valores inseridos na subjetividade das categorias acima referidas. Procuramos analisar o impacto da introduÃÃo dos medicamentos genÃricos no mercado e suas conseqÃÃncias no contexto da relaÃÃo das categorias citadas. Explorou-se tambÃm a lÃgica do mercado farmacÃutico e seu grau de influÃncia sobre a populaÃÃo, principalmente, sobre os prescritores. A metodologia utilizada baseou-se na
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Mendonça, Pedro Alerrandro Saccol. "Impactos concorrenciais da entrada dos medicamentos genéricos no mercado farmacêutico brasileiro de 2003 a 2007." Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=3060.

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Em 1999, o mercado de medicamentos genéricos foi criado no Brasil. Com isso, iniciou-se uma nova fase do mercado farmacêutico brasileiro. Através de dados cedidos pela ANVISA sobre o mercado varejista brasileiro, objetivou-se testar em até que ponto a política de medicamentos genéricos tem logrado êxito. Foram utilizados dados em painel para analisar o impacto da entrada dos medicamentos genéricos sobre a estrutura do mercado, assim como o impacto nos preços e na quantidade vendida entre 2003 e 2007. Os resultados foram favoráveis à diminuição da concentração dos mercados relevantes da amostra
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Sobral, Flávia Cavalcante. "Medicamentos genéricos: as representações sociais dos consumidores da cidade do salvador." Universidade Federal da Bahia, 2006. http://www.adm.ufba.br/sites/default/files/publicacao/arquivo/flavia_cavalcante_sobral.pdf.

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p. 1-104<br>Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-03-06T20:06:34Z No. of bitstreams: 1 wwww14.pdf: 1450489 bytes, checksum: ae0e213bd3a56fc00ceab3623f52cb06 (MD5)<br>Approved for entry into archive by Tatiana Lima(tatianasl@ufba.br) on 2013-03-14T18:32:28Z (GMT) No. of bitstreams: 1 wwww14.pdf: 1450489 bytes, checksum: ae0e213bd3a56fc00ceab3623f52cb06 (MD5)<br>Made available in DSpace on 2013-03-14T18:32:28Z (GMT). No. of bitstreams: 1 wwww14.pdf: 1450489 bytes, checksum: ae0e213bd3a56fc00ceab3623f52cb06 (MD5) Previous issue date: 2006<br>A preocupação em en
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Грабовська, О. В. "Економічний аналіз міжнародного та національного ринку фармацевтичної продукції". Master's thesis, Сумський державний університет, 2018. http://essuir.sumdu.edu.ua/handle/123456789/71513.

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Магістерська робота присвячена аналізу глобального та українського ринку фармацевтичної продукції. Вона аналізує поточну ситуацію на ринку, ризики та переваги, основні рушійні сили та основних гравців на ринку. Головна мета цього дослідження — провести аналіз ринку для міжнародної компанії.<br>The master’s thesis focuses on the analysis of the global and Ukrainian market of pharmaceutical products. It examines the current situation on the market, its risks and benefits, the main driving forces and the main players on the market. The main aim of this study is to conduct the market analysis for
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Maurin, Karlsson Therese, Elin Milveden, and Nina Larsson. "The generic drug market in the Netherlands : A MARKET ANALYSIS." Thesis, Uppsala University, Department of Business Studies, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-127040.

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Wouters, Olivier. "Essays on prices, volumes, and policies in generic drug markets in high- and middle-income countries." Thesis, London School of Economics and Political Science (University of London), 2018. http://etheses.lse.ac.uk/3827/.

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Background and importance: Rising drug prices are putting pressure on health care budgets. Policymakers are assessing how they can save money through generic drugs. Objective: The aim of this Ph.D. was to explore issues relating to the prices and usage of generic medicines in high- and middle-income countries in five articles. This was done using quantitative and qualitative methods, including price and Herfindahl-Hirschman indexes, difference-in-differences regression analyses, semi-structured stakeholder interviews, and literature reviews. As a Ph.D. "thesis by papers", each of the five arti
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Jordan, Tamara. "Identification of genetic markers that predict cancer sensitivity to the anticancer drugs 5-FU and Irinotecan." Thesis, Bangor University, 2015. https://research.bangor.ac.uk/portal/en/theses/identification-of-genetic-markers-that-predict-cancer-sensitivity-to-the-anticancer-drugs-5fu-and-irinotecan(f0c36c3f-6cdd-4e9a-8948-b89c84e0b5ed).html.

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Masiulis, Mindaugas. "Vilniaus miesto šeimos gydytojų požiūris į farmacinės kompanijos atstovo vizitus." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130605_160418-39362.

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Darbo tikslas- įvertinti Vilniaus miesto šeimos gydytojų požiūrį į farmacinės kompanijos atstovo vizitus. Tyrimo metodika. 2012 metų rugpjūčio – gruodžio mėnesiais, buvo apklausti Vilniaus miesto šeimos gydytojai dirbantys pirminės šeimos sveikatos priežiūros centruose. Buvo išdalinta 200 anketų, atsakė - 132 respondentai (atsakas – 66 proc.). Anketiniai duomenys analizuoti naudojant statistinę analizės programą SPSS 14.0 . Statistinis duomenų reikšmingumas tikrintas pagal Chi kvadrato kriterijų, laisvės laipsnių skaičių ir statistinį reikšmingumą (p). Statistinių hipotezių reikšmingumui įver
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Books on the topic "Generic Drugs Market"

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(Firm), Find/SVP. The market for generic drugs. FIND/SVP Research Publications Group, 1998.

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Frost & Sullivan., ed. The U.S. market for generic drugs. Frost & Sullivan, 1989.

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inc, International Resource Development, ed. Generic drugs in the 1990s. International Resource Development, 1988.

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Bassett, Pamela. Generic drugs: Technologies, trends, and market opportunities. D&MD, 2002.

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Crandall, Mary Anne. The market for generic biologics. Edited by Heffner Steven and Kalorama Information LLC. Kalorama Information, 2004.

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Gray, Lynn. The U.S. generic prescription drug industry. Business Communications Co., 2002.

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Gray, Lynn. The worldwide generic prescription drug industry. Business Communications Co., 1999.

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Handa, Pavan. The worldwide generic prescription drug industry. Business Communications Co., Inc., 1996.

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Frank, Richard G. Pricing, patent loss and the market for pharmaceuticals. National Bureau of Economic Research, 1991.

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Raggett, Tom. Generic pharmaceuticals: Implications for the global pharmaceutical industry. Financial Times Business Information, 1994.

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Book chapters on the topic "Generic Drugs Market"

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Raju, K. D. "Patent Linkages and Its Impact on Access to Medicines: Challenges, Opportunities for Developing Countries." In Access to Medicines and Vaccines. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83114-1_12.

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AbstractLinking patent protection to generics’ regulatory approvals is a heated topic of discussions and a friction point among countries proposing higher protection for patented drugs. Patent linkage has been pushed through bilateral and regional agreements outside of the WTO system. It is widely understood that patent linkage is implemented to delay the market entry of generic medicines. It is argued here that developing countries are not obliged to take up TRIPs plus patent-linkage obligations.A list of approved drugs and their therapeutic equivalence can be published by every country. The
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Nouguez, Etienne. "In whose best interest? Framing pharmacists' and physicians' (conflicts of) interest in the French market for generic drugs." In Conflict of Interest and Medicine. Routledge, 2021. http://dx.doi.org/10.4324/9781003161035-6.

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Eleonorasdotter, Emma. "Drugs, Alcohol and Medicine in Sweden." In Women’s Drug Use in Everyday Life. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-46057-9_2.

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AbstractThis background chapter sets the scene for the ethnographic study of Swedish women who use drugs (Part II of this book). It reviews historical and contemporary research on, and cultural representations of, drugs, paying specific attention to class and gender. How drugs first came into use in the Western world is examined under the heading Drug Laws and Drug Culture, and from there how they spread and how different substances and preparations came to be regarded from a legal and moral perspective. Why is alcohol not obviously perceived as a drug, and what roles do class and gender play
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Shoulders, C. C., M. J. Ball, J. I. Mann, and F. E. Baralle. "A Genetic Marker in the Apolipoprotein AI/CIII Gene Complex Associated with Hypercholesterolaemia." In Drugs Affecting Lipid Metabolism. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71702-4_10.

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Kassab, Hanna Samir, and Jonathan D. Rosen. "General Trends in Drug Trafficking and Organized Crime on a Global Scale." In Illicit Markets, Organized Crime, and Global Security. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90635-5_5.

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Mackintosh, Maureen, Sudip Chaudhuri, Nazeem Mohamed, Samuel Wangwe, Twalib Ngoma, and Veronica Manduku. "Oncology Drug Production in Sub-Saharan Africa: The Challenge and Opportunity, with Evidence from India." In Cancer Care in Pandemic Times: Building Inclusive Local Health Security in Africa and India. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44123-3_8.

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AbstractThis chapter focuses on the scope for local production in East Africa of essential oncology medication, drawing on evidence of local clinical need; on Indian data on markets for generic oncology medication; and on industrial and regulatory experience. Import-dependence in oncology is almost complete across Sub-Saharan Africa, while India is a key exporter. The chapter documents competition failures in generic oncology markets and demonstrates the huge affordability impact of effective procurement of these medicines within India. Challenges for local oncology manufacturing are identifie
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Frisvold, George B. "Bioprospecting and Incentives for Biodiversity Conservation: Lessons from the History of Paclitaxel." In Sustainable Resource Development in the 21st Century. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-24823-8_14.

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AbstractPlants and other organisms remain an important source of new medicines, either directly or as sources of molecular building blocks or information for drug development. Bioprospecting contracts between pharmaceutical companies and species-rich source countries have been touted as a way for developing countries to capture greater gains from their genetic resources and to increase their incentives to preserve their biodiversity. This case study of the discovery and commercial development of the anticancer drug paclitaxel from the Pacific yew tree highlights neglected issues in debates ove
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Correa, Marilena, Maurice Cassier, and Maria Andrea Loyola. "Regulating the Copy Drug Market in Brazil: Testing Generics and Similar Medicines (1999–2015)." In Health Innovation and Social Justice in Brazil. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-76834-2_10.

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Massard da Fonseca, Elize. "Assessing the Generic Drug Regulatory Process in the 2000s: Governmental Intervention, Market Demand and Local Pharmaceutical Industries." In The Politics of Pharmaceutical Policy Reform. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-12565-7_4.

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Barcelo, Racquel C., Mark Gamaliel S. Gallao II, Reina G. Balocnit, et al. "Traditional Medicinal Knowledge of Vendors and Their Contribution Toward Community Healthcare in Baguio City, Philippines." In Case Studies in Biocultural Diversity from Southeast Asia. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6719-0_6.

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AbstractHerbal plants are among the products sold in many urban markets in Asia. They play a vital role in alleviating various and common ailments among city-dwellers. People buy them because of their availability, ease of preparation, low cost, and effectiveness as compared to synthetic and commercial drugs. This study was conducted to identify and document the uses of the medicinal plants sold in the streets and market places of Baguio City, Philippines. Information on the part/s used, method of preparation, and mode of use/application were collected through semi-structured questionnaires an
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Conference papers on the topic "Generic Drugs Market"

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Markopoulos, Evangelos, and Chrystalla Protopapa. "Machine Reading Comprehension and Expert System technologies for social innovation in the drug excipient selection process." In 14th International Conference on Applied Human Factors and Ergonomics (AHFE 2023). AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1003273.

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The growth of the global population together with several unpredicted crises such as political, health, and financial, create an environment of uncertainty in which social innovations can be developed to offer stability in people’s lives and create new business development opportunities for the benefit of the economy and the society. One of the undoubted rights of every human being is access to affordable medical treatment. However, the costs and time needed for research and development on new or specialized drugs are not often covered by governmental budgets and initiatives that could make su
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Moskalets, O. V. "Anti-rituximab antibodies in refractory / relapsing cases of chronic lymphocytic leukemia." In General question of world science. L-Journal, 2020. http://dx.doi.org/10.18411/gq-30-11-2020-02.

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Rituximab, a chimeric monoclonal antibody targeted against the pan-B-cell marker CD20, is widley used for treatment of lymphomas, rheumatologic diseases and other – 8 – General question of world science disorders. It is known that many monoclonal antibodies such as rituximab can elicit anti-drug antibodies, which may interfere with therapeutic response. The aim of this study was to investigate the incidence of antibodies to rituximab in patients with chronic lymphocytic leukemia. Serum concentrations of anti-rituximab antibodies was determined in blood serum of patients with B-chronic lymphocy
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Udagawa, Chihiro, Yasushi Sasaki, Hiroshi Suemizu, et al. "Abstract 5027: Exome sequencing of cancer-related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5027.

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Dronova, T. A., N. N. Babyshkina, E. M. Slonimskaya, and N. V. Cherdyntseva. "ASSESSMENT OF DISEASE PROGRESSION IN ESTROGEN-POSITIVE BREAST CANCER PATIENTS TREATED TAMOXIFEN." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-319.

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The aim: to study the expression status of ERα, TGF-βR2, pAkt to assess the breast cancer progression when prescribing drug therapy with tamoxifen. ESR1 gene expression level, TGF-βR2 and pAkt protein expression as well as the populations of pAkt–/TGFβR2+ cells were identified as additional molecular genetic markers for the prognosis of estrogen-positive breast cancer.
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Sharma, Jai, and Vidhyacharan Bhaskar. "An Rna Sequencing Analysis of Glaucoma Genesis in Mice." In 12th International Conference on Artificial Intelligence, Soft Computing and Applications. Academy and Industry Research Collaboration Center (AIRCC), 2022. http://dx.doi.org/10.5121/csit.2022.122306.

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Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern development of Next-Generation Sequencing (NGS) technologies, scientists are starting to learn more about the genetic origins of Glaucoma. This research uses differential expression (DE) and gene ontology (GO) analyses to study the genetic differences between mice with severe Glaucoma and multiple control groups. Optical nerve head (ONH) and retina data samples
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Ranjan, Shashi, and Yong Zhang. "Capture of Circulating Tumor Cells (CTCs) Using a Novel Micro-Device." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53030.

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Circulating tumor cells (CTCs) are metastatic cells that are detached from a tumor and are found in the blood of cancer patients. The presence of CTCs in the blood indicates the metastatic stage of cancer, so the detection of CTCs has been considered as a diagnosis and prognosis marker. The number of CTCs in blood has been found to be related with survival-rate. Also, CTCs have spurred interest for understanding the biology of these cells by performing genetic-level analysis which can be helpful in the development of targeted cancer-therapy or in drug-selection.
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Hohlova, Vera, and Baiba Rivza. "The Impact of the COVID-19 pandemic on the unemployment rate in Latvia." In Research for Rural Development 2021 : annual 27th International scientific conference proceedings. Latvia University of Life Sciences and Technologies, 2021. http://dx.doi.org/10.22616/rrd.27.2021.020.

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The economic and labour market consequences of Covid-19 were immediate, significant and lasting, with longterm negative effects on global economic development and activity in general. The global virus pandemic is having a profound effect on the labour market with a sharp rise in the number of unemployed, which are at high risk of becoming long-term unemployed as the pandemic drags on, some of whom will not return to the labour market. The outbreak of Covid-19 and the measures taken to combat it are leading to a rapid demand for unemployment benefits, but a large proportion of the unemployed re
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Dudnic, Eugeniu, and Natalia Dudnic. "Anti-doping control in sport." In The International Scientific Congress "Sports. Olimpysm. Health". SOH 2023. 8th Edition. The State University of Physical Education and Sport, 2025. https://doi.org/10.52449/soh23.17.

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Anti-doping control encountered complicated problems, such as obtaining a consensus on the definition of doping, distinguishing doping from legitimate medical treatment, establishing the evidence of a doping case. At the same time, the proposals for solving these problems often conflicted with national or international laws, so that a lack of standardization in the procedures was manifested. In 1990, the Council of Europe adopted the Anti-Doping Convention, in which 28 EU member countries participate. The main achievement of the convention is that it obliges governments to adopt minimum standa
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Gholoom, Sheikha Ishaq Abdallah, and Panagiotis D. Zervopoulos. "The Effect of Mergers and Acquisitions on Efficiency: Evidence from the Pharmaceutical Industry." In International Symposium on Engineering and Business Administration. Trans Tech Publications Ltd, 2023. http://dx.doi.org/10.4028/p-qlbab6.

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This study emphasizes the assessment of efficiency and the degree of operating efficiency of mergers and acquisitions in the pharmaceutical industry worldwide. This industry encounters various challenges such as expiring patents, the rise of genetics pharmaceuticals, the entrance of biotechnology companies in the pharmaceutical market, the increasing research and development expenses, government regulations of the pharmaceutical industry, distribution channels, and drug prices. All these challenges result in an intensely competitive environment in which pharmaceuticals suffering from shortcomi
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Fletcher, Rich. "Modifying oil and protein quality in hemp using modern conventional breeding approaches." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/ugom7222.

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Cannabis sativa. has been cultivated as a source of high-quality fiber, nutritious grain and physiologically active molecules for thousands of years. Marijuana and hemp are both phenotypes of C. sativa, differentiated on the concentration of the psychoactive molecule delta-9-tetrahydocannabinol (THC) present in female flowers. Hemp, by definition, synthesizes less than 0.3% THC whereas all other plants would qualify as marijuana. Hemp grain is 30% lipid with a fatty acid composition elevated in omega-3 and omega-6 fatty acids, particularly gamma-linolenic acid. Hemp is also recognized for a hi
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Reports on the topic "Generic Drugs Market"

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Tulum, Öner, and William Lazonick. Setting Pharmaceutical Drug Prices: What the Medicare Negotiators Need to Know About Innovation and Financialization. Institute for New Economic Thinking Working Paper Series, 2024. http://dx.doi.org/10.36687/inetwp226.

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Mandated by the Inflation Reduction Act of 2022, the U.S. government through the Centers for Medicare and Medicaid Services (CMS) is negotiating with pharmaceutical companies over the “maximum fair price” of ten drugs in wide use by Medicare patients. Over the next few years, the number of drugs whose prices are subject to negotiations will increase. The pharmaceutical companies contend that a “fair” price would be a “value-based price” that enables the companies’ shareholders to capture the value that the drug creates for society. Invoking the dominant “maximizing shareholder value” ideology,
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Berndt, Ernst, Rena Conti, and Stephen Murphy. The Landscape of US Generic Prescription Drug Markets, 2004-2016. National Bureau of Economic Research, 2017. http://dx.doi.org/10.3386/w23640.

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Conti, Rena, and Ernst Berndt. Four Facts Concerning Competition in U.S. Generic Prescription Drug Markets. National Bureau of Economic Research, 2019. http://dx.doi.org/10.3386/w26194.

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Cahaner, Avigdor, Susan J. Lamont, E. Dan Heller, and Jossi Hillel. Molecular Genetic Dissection of Complex Immunocompetence Traits in Broilers. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586461.bard.

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Objectives: (1) Evaluate Immunocompetence-OTL-containing Chromosomal Regions (ICRs), marked by microsatellites or candidate genes, for magnitude of direct effect and for contribution to relationships among multiple immunocompetence, disease-resistance, and growth traits, in order to estimate epistatic and pleiotropic effects and to predict the potential breeding applications of such markers. (2) Evaluate the interaction of the ICRs with genetic backgrounds from multiple sources and of multiple levels of genetic variation, in order to predict the general applicability of molecular genetic marke
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Atal, Juan Pablo, Úrsula Giedion, Catalina Gutiérrez, and Natalia Jorgensen. What is the Opportunity Cost of Financing Branded Drugs?: The case of the Dominican Republic. Inter-American Development Bank, 2023. https://doi.org/10.18235/0012896.

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The availability of numerous beneficial healthcare technologies presents both an opportunity and a challenge: while they have the potential to improve health outcomes, financial constraints limit their widespread adoption. This challenge is further exacerbated by an aging population and shifting epidemiological trends, which place increasing pressure on global healthcare expenditures. To ensure that rising healthcare costs translate into meaningful improvements in population health, it is essential that spending remains sustainable, does not displace other critical investments, and aligns with
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Apiyo, Eric, Zita Ekeocha, Stephen Robert Byrn, and Kari L. Clase. Improving Pharmacovigilliance Quality Management System in the Pharmacy and Poisions Board of Kenya. Purdue University, 2021. http://dx.doi.org/10.5703/1288284317444.

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The purpose of this study was to explore ways of improving the pharmacovigilance quality system employed by the Pharmacy and Poisons Board of Kenya. The Pharmacy and Poisons Board of Kenya employs a hybrid system of pharmacovigilance that utilizes an online system of reporting pharmacovigilance incidences and a physical system, where a yellow book is physically filled by the healthcare worker and sent to the Pharmacy and Poisons Board for onward processing. This system, even though it has been relatively effective compared to other systems employed in Africa, has one major flaw. It is a slow a
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Shujaa, Asaad Suliman, and Qasem Almulihi. The efficacy and safety of ketamine in treating refractory and super-refractory status epilepticus in pediatric and adult populations, A systemic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0011.

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Review question / Objective: This study is to assess the efficacy and safety of ketamine in treating refractory and super-refractory status epilepticus in pediatric and adult populations. Rationale: Refractory status epilepticus (RSE) is either generalized or complex partial status epilepticus (SE) that fails to respond to first and second-line therapies. Super refractory status epilepticus (SRSE) is SE that remains unresponsive despite 24 hours of therapy with general anesthesia [1, 2]. Both RSE and SRSE pose significant challenges for the managing intensivist. There exists a race against tim
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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patien
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Willis, C., F. Jorgensen, S. A. Cawthraw, et al. A survey of Salmonella, Escherichia coli (E. coli) and antimicrobial resistance in frozen, part-cooked, breaded or battered poultry products on retail sale in the United Kingdom. Food Standards Agency, 2022. http://dx.doi.org/10.46756/sci.fsa.xvu389.

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Frozen, breaded, ready-to-cook chicken products have been implicated in outbreaks of salmonellosis. Some of these outbreaks can be large. For example, one outbreak of Salmonella Enteritidis involved 193 people in nine countries between 2018 and 2020, of which 122 cases were in the UK. These ready-to-cook products have a browned, cooked external appearance, which may be perceived as ready-to-eat, leading to mishandling or undercooking by consumers. Continuing concerns about these products led FSA to initiate a short-term (four month), cross-sectional surveillance study undertaken in 2021 to det
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Stall, Nathan M., Kevin A. Brown, Antonina Maltsev, et al. COVID-19 and Ontario’s Long-Term Care Homes. Ontario COVID-19 Science Advisory Table, 2021. http://dx.doi.org/10.47326/ocsat.2021.02.07.1.0.

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Key Message Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. There are several measures that could be effective in preventing COVID-19 outbreaks, hospitalizations, and deaths in Ontario’s LTC homes, if implemented. First, temporary staffing could be minimized by improving staff working conditions. Second, homes could be further decrowded by a continued disallowance of three- and four-resident rooms and additional temporary housing for the most crowded h
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