Academic literature on the topic 'Genetic gain trial'

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Journal articles on the topic "Genetic gain trial"

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Breseghello, Flávio, Orlando Peixoto de Morais, and Paulo Hideo Nakano Rangel. "A new method to estimate genetic gain in annual crops." Genetics and Molecular Biology 21, no. 4 (1998): 551–55. http://dx.doi.org/10.1590/s1415-47571998000400024.

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The genetic gain obtained by breeding programs to improve quantitative traits may be estimated by using data from regional trials. A new statistical method for this estimate is proposed and includes four steps: a) joint analysis of regional trial data using a generalized linear model to obtain adjusted genotype means and covariance matrix of these means for the whole studied period; b) calculation of the arithmetic mean of the adjusted genotype means, exclusively for the group of genotypes evaluated each year; c) direct year comparison of the arithmetic means calculated, and d) estimation of m
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Corfitsen, Henrik Thyge, Betina Krantz, Agnete Larsen, and Antonio Drago. "Molecular pathway analysis associates alterations in obesity-related genes and antipsychotic-induced weight gain." Acta Neuropsychiatrica 32, no. 2 (2019): 72–83. http://dx.doi.org/10.1017/neu.2019.41.

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AbstractObjective:Antipsychotics often induce excessive weight gain. We hypothesised that individuals with genetic variations related to known obesity-risk genes have an increased risk of excessive antipsychotic-induced weight gain (AIWG). This hypothesis was tested in a subset of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial data set.Methods:The CATIE trial compared effects and side effects of five different antipsychotics through an 18-month period. Based on the maximum weight gain recorded, excessive weight gain was defined as >7% weight gain. Cytoscape an
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Gonçalves, Paulo de Souza, Adriano Tosoni da Eira Aguiar, Reginaldo Brito da Costa, Elaine Cristine Piffer Gonçalves, Erivaldo José Scaloppi Júnior, and Roberto Botelho Ferraz Branco. "Genetic variation and realized genetic gain from rubber tree improvement." Scientia Agricola 66, no. 1 (2009): 44–51. http://dx.doi.org/10.1590/s0103-90162009000100006.

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Breeding cycle in rubber extends to 20-30 years between pollination and yield assessment, distributed over three selection stages. Five hectares of small scale trial of rubber tree [Hevea brasiliensis (Willd. ex Adr. de Juss.) Muell.-Arg.], was established in the Northwestern region of São Paulo State, Brazil. The population comprises 98 clones mostly derived from intensively selected plus tree in the natural forest of rubber tree in the Amazon. Three open pollinated progeny tests were established in three experimental stations. Seedlings from 98 progenies including a commercial check (CC) wer
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Greveniotis, Vasileios, and Vasilia A. Fasoula. "Application of prognostic breeding in maize." Crop and Pasture Science 67, no. 6 (2016): 605. http://dx.doi.org/10.1071/cp15206.

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Innovative approaches and new efficiencies in plant breeding are required to accelerate the progress of genetic improvement through selection. One such approach is the application of prognostic breeding, which is an integrated crop-improvement methodology that enables selection of plants for high crop yield potential by evaluating its two components: plant yield potential and stability of performance. Plant yield and stability are assessed concurrently in each generation by utilising the plant prognostic equation. The genetic material used for this study was 2350 F2 plants (C0) of the commerci
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Nirsatmanto, Arif, Teguh Setyaji, and Wahyuningtyas Reny Setyo. "REALIZED GENETIC GAIN AND SEED SOURCE X SITE INTERACTION ON STAND VOLUME PRODUCTIVITY OF ACACIA MANGIUM." JOURNAL OF FORESTRY RESEARCH 1, no. 1 (2014): 21–32. https://doi.org/10.20886/ijfr.2014.1.1.21-32.

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Following the results of the comprehensive tree improvement programs for Acacia mangium, it is necessary to estimate the real amount of genetic improvement and to develop an improved seed deployment strategy.  This study was aimed to verify realized genetic gain on stand volume productivity attained by the first-generation Seedling Seed Orchards (SSO) of A. mangium and to identify the magnitude of seed sources x site interaction as a basis for improved seed deployment. Seeds from five SSOs were tested together with seeds from seed stand in genetic gain trials which were established in Sou
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Kumar, S., H. S. Dungey, and A. C. Matheson. "Genetic Parameters and Strategies for Genetic Improvement of Stiffness in Radiata Pine." Silvae Genetica 55, no. 1-6 (2006): 77–84. http://dx.doi.org/10.1515/sg-2006-0012.

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Abstract The two main objectives of this study were: (1) to determine how early is it possible to undertake selection to improve the stiffness of corewood; (2) to determine if the selection based on corewood stiffness could also improve outerwood stiffness, and vice versa. Breastheight data from two progeny trials of Pinus radiata D. Don were used. In the first trial (age 30 years), data on Silviscan predicted stiffness (MoE) was obtained for each growth ring on each core sample from 50 open-pollinated families. In the second trial (age 14 years), data on static-bending MoE was obtained using
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dos Santos, Wanderley, Danilla Cristina Lemos Souza, Mário Luiz Teixeira de Moraes, and Ananda Virginia de Aguiar. "Genetic variation of wood and resin production in Pinus caribaea var. hondurensis Barret & Golfari." Silvae Genetica 65, no. 1 (2016): 31–37. http://dx.doi.org/10.1515/sg-2016-0004.

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Abstract The purpose of this work was to estimate genetic parameters and selection gain of Pinus caribaea var. hondurensis progeny trial for wood and resin production as well as correlation between them. Experiment was established in complete lattice square 10 × 10 (triple), 100 treatments, 10 plants per plot, 3 m × 3 m spacing. Twelve years after planting the trial had thinned considerably leaving six plants per plot. Twenty-seven years after planting height, diameter at breast height (dbh) and resin production were measured. Deviance analysis, genetic parameter estimates, selection expected
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Sumardi, Sumardi, Hery Kurniawan, and Prastyono Prastyono. "GENETIC PARAMETER ESTIMATES FOR GROWTH TRAITS IN AN Eucalyptus Urophylla S.T. Blake PROGENY TEST IN TIMOR ISLAND." JOURNAL OF FORESTRY RESEARCH 3, no. 2 (2016): 119–27. https://doi.org/10.20886/ijfr.2016.3.2.119-127.

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Genetic parameters were estimated for growth traits of Ampupu (<em>Eucalyptus urophylla</em> S.T. Blake) progeny test grown in Southern Central Timor - East Nusa Tenggara Province, Timor Island. When the trial was one year old data were collected from 45 half-sib open pollinated families and assessed. There were genetic variations in height and diameter among families of E. urophylla. Growth traits had moderate heritability, both individually and in family, i.e. 0.28 and 0.55 for height and 0.41 and 0.66 for diameter, respectively. Genetic correlation between height and diameter was strong (0.
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Sumardi, Sumardi, Hery Kurniawan, and Prastyono Prastyono. "GENETIC PARAMETER ESTIMATES FOR GROWTH TRAITS IN AN Eucalyptus Urophylla S.T. Blake PROGENY TEST IN TIMOR ISLAND." Indonesian Journal of Forestry Research 3, no. 2 (2016): 119–27. https://doi.org/10.59465/ijfr.2016.3.2.119-127.

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Genetic parameters were estimated for growth traits of Ampupu (Eucalyptus urophylla S.T. Blake) progeny test grown in Southern Central Timor - East Nusa Tenggara Province, Timor Island. When the trial was one year old data were collected from 45 half-sib open pollinated families and assessed. There were genetic variations in height and diameter among families of E. urophylla. Growth traits had moderate heritability, both individually and in family, i.e. 0.28 and 0.55 for height and 0.41 and 0.66 for diameter, respectively. Genetic correlation between height and diameter was strong (0.96). Howe
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Klápště, J., M. Lstibůrek, and J. Kobliha. "Initial evaluation of half-sib progenies of Norway spruce using the best linear unbiased prediction." Journal of Forest Science 53, No. 2 (2008): 41–46. http://dx.doi.org/10.17221/2136-jfs.

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The present paper deals with data obtained from fifteen years old Norway spruce (&lt;i&gt;Picea abies&lt;/i&gt; [L.] Karst.) progeny test established at three sites in the Sázava River region. Parameter under the evaluation was a tree height in 15 years following the establishment of the trial. Genetic parameters were estimated using the REML (Restricted Maximum Likelihood) procedure followed by the BLUP (Best Linear Unbiased Prediction). Genetic parameters estimates were used to predict genetic gain in three alternative selection strategies. The value of gain depends on target value of gene d
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Dissertations / Theses on the topic "Genetic gain trial"

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Vidal, Marjorie. "Optimisation des stratégies d'amélioration génétique du pin maritime grâce à l'utilisation de marqueurs moléculaires." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0044/document.

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Le pin maritime (Pinus pinaster Ait.) est l’une des principales espèces forestières en France, fournissant près d’un quart de la production nationale de bois. Un programme d’amélioration, mis en place dans les années 1960, propose des variétés génétiquement améliorées pour la croissance et la rectitude du tronc.Cette thèse explore la possibilité d’introduire les marqueurs moléculaires dans les stratégies d’amélioration génétique du pin maritime en Aquitaine. Les marqueurs sont utilisés afin de reconstituer a posteriori les pedigrees au sein d’un test de descendance « polycross », pour d’une pa
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Lingam, Varatharajan. "Effects of Generic Group-Based Versus Personalized Individual-Based Exercise Programs on Balance, Gait, and Functional Performance of Older Adults with Mild Balance Dysfunction and Living in Residential Care Facilities - A Randomized Controlled Trial." Diss., NSUWorks, 2019. https://nsuworks.nova.edu/hpd_pt_stuetd/82.

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Background and Purpose: To investigate the effect of an individualized exercise program versus a generic group-based exercise program on balance, gait, and functional performance of older adults categorized as having mild balance dysfunction and living in residential care facilities. Methods: Single blind randomized control design. One hundred-twenty residents fulfilled screening criteria for mild balance dysfunction based on the BioSwayTM balance and the Multi-Directional Reach Test (MDRT) primary outcome measures. Secondary assessment was completed using the Modified Physical Performance Tes
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Lyon, Peter. "Genetic analysis with gain estimation from a provenance trial/breeding orchard of Acacia mangium Willd. at Bengkoka, Sabah, Malaysia." Thesis, 1997. http://hdl.handle.net/1885/145762.

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Books on the topic "Genetic gain trial"

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Mcdermott, Leeanne. GamePro Presents: Sega Genesis Games Secrets: Greatest Tips. Prima Publishing, 1992.

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Book chapters on the topic "Genetic gain trial"

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Singh, Ravi P., Philomin Juliana, Julio Huerta-Espino, et al. "Achieving Genetic Gains in Practice." In Wheat Improvement. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-90673-3_7.

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AbstractAccelerating the rate of genetic gain for grain yield together with key traits is pivotal for delivering improved wheat varieties. The key strategies of CIMMYT’s spring bread wheat improvement program to continuously increase genetic gains and deliver elite wheat lines to national partners in the target countries include: breeding for product profiles that prioritize selection traits; robust choice of diverse parents by leveraging all phenotypic and genotypic data; effective crossing schemes with an optimal proportion of different types of crosses; early-generation advancement using th
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Lau L.M.S., Dimitrova V.G., Yang-Turner F., Tzagarakis M., Karacapilidis N., and Christodoulou S. "Understanding Collaborative Sensemaking Behaviour using Semantic Types in Interaction Data." In Frontiers in Artificial Intelligence and Applications. IOS Press, 2014. https://doi.org/10.3233/978-1-61499-405-3-190.

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This paper presents a trial study to gain insight into collaborative sensemaking behaviour. We use a generic argumentation tool to capture interaction data, which is then analyzed by exploiting collaboration-specific semantic types. A Community Behaviour Analytics Tool, CommBAT, was developed. Further studies were conducted to visualize the different patterns in the collaborative behaviour. Initial findings show the power of semantics in helping to detect a series of sensemaking behaviour patterns.
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Biesecker, Barbara B., Kathryn F. Peters, and Robert Resta. "Research in Genetic Counseling." In Advanced Genetic Counseling. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190626426.003.0010.

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The field of genetic counseling has historically valued the role of research. More recently, graduate programs have raised the standards for student thesis projects so that a greater percent are of publishable quality. The profession has acknowledged key research gaps, such as a lack of consensus on the primary client outcomes of counseling. Further, the National Society of Genetic Counselors has endorsed the importance of evidence that may be used to guide practice. Herein we present the role of genetic counselors as researchers and discuss approaches to designing research studies to answer k
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Halliday, Brian P., and Thomas F. Lüscher. "Clinical phenotypes of heart failure with reduced ejection fraction." In The ESC Textbook of Heart Failure, edited by Petar M. Seferović, Andrew J. S. Coats, Gerasimos Filippatos, Stefan D. Anker, Johann Bauersachs, and Giuseppe Rosano. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780198891628.003.0028.

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Abstract Following the use of left ventricular ejection fraction (LVEF) in early trials to select patients thought most likely to gain benefit from therapies, heart failure has been classified based on this measure. Indeed, more recent trials have confirmed the remarkable ability of LVEF to select patients with reduced systolic function who are most likely to benefit from pharmacological therapies. Additional classification of patients with heart failure with reduced ejection fraction (HFrEF) is often based on the presence or absence of ischaemic heart disease significant enough to cause the d
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Isom, Lori L., and Kelly G. Knupp. "Targeted Augmentation of Nuclear Gene Output (TANGO)." In Jasper's Basic Mechanisms of the Epilepsies, 5th ed., edited by Michael A. Rogawski. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197549469.003.0075.

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Abstract Most development and epileptic encephalopathies (DEEs) are genetic in origin. Drug-resistant epilepsy is often the most notable feature of the DEEs, although numerous other symptoms are present that have significant impact on patients’ quality of life. Despite novel, third-generation antiseizure drug treatment options becoming available over the last several years, seizure freedom is often not attained and nonseizure symptoms remain. Therapeutic approaches such as antisense oligonucleotides and adeno-associated virus delivered gene modulation offers realistic hope for seizure freedom
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Aggarwal, Ritu, and Suneet Kumar. "Missing Value Imputation and Estimation Methods for Arrhythmia Feature Selection Classification Using Machine Learning Algorithms." In Machine Learning Methods for Engineering Application Development. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9879815079180122010013.

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&amp;nbsp;Electrocardiogram signal analysis is very difficult to classify cardiac arrhythmia using machine learning methods. The ECG datasets normally come with multiple missing values. The reason for the missing values is the faults or distortion. When performing data mining, missing value imputation is the biggest task for data preprocessing. This problem could arise due to incomplete medical datasets if the incomplete missing values and cases were removed from the original database. To produce a good quality dataset for better analyzing the clinical trials, the suitable missing value imputa
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Drummond Eleanor, Goñi Fernando, Liu Shan, Prelli Frances, Scholtzova Henrieta, and Wisniewski Thomas. "Potential Novel Approaches to Understand the Pathogenesis and Treat Alzheimer's Disease." In Advances in Alzheimer’s Disease. IOS Press, 2018. https://doi.org/10.3233/978-1-61499-876-1-297.

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There is growing genetic and proteomic data highlighting the complexity of Alzheimer's disease (AD) pathogenesis. Greater use of unbiased &amp;ldquo;omics&amp;rdquo; approaches is being increasingly recognized as essential for the future development of effective AD research, that need to better reflect the multiple distinct pathway abnormalities that can drive AD pathology. The track record of success in AD clinical trials thus far has been very poor. In part, this high failure rate has been related to the premature translation of highly successful results in animal models that mirror only lim
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Dash, Lipsa, Sukanta Kumar Sahoo, Feroz H. Rahman, et al. "Kendrapada Sheep: An Insight Into Productivity and Genetic Potential of this Prolific Breed." In Sheep Farming - Herds Husbandry and Management System, Reproductive and Improving Animal Health [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101289.

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Kendrapada sheep of Odisha is a prolific, medium stature meat type breed. The Kendrapada sheep is the second prolific sheep of India after Garrole of West Bengal, which carries FecB mutation, responsible for prolificacy. The reproductive traits of this sheep is the major attribute where the ewe of this sheep comes to heat at around 10–11 months and drops its first lamb at around 15–16 months of age. The average lambing interval in these sheep is 8 months with gestation period of 150 days. The reproductive performance of these sheep is the uniqueness of this sheep population with more than 70%
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Srinivasan, Parthi. "Treatment of diabetes (Type I) through transplantation." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1597.

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Type 1 diabetes mellitus (T1DM) is an autoimmune disease associated with selected genetic HLA alleles, which results in the permanent destruction of beta cells of the pancreatic islets of Langerhans, with subsequent insulinopenia and hyperglycaemia (1). Meta-analysis indicates that high birth weight and increased early weight gain may be risk factors for type 1 diabetes (2). The clinical state leads to significant increase in premature mortality and morbidity, including through accelerated atherosclerosis, cardiac autonomic neuropathy, and possibly intrinsic cardiomyopathy (3). Intensive exoge
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Conference papers on the topic "Genetic gain trial"

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Pietsch, Torsten, Evelyn Doerner, Anja zur Muehlen, et al. "Abstract LB-82: Chromosome 1q gain as genetic marker for risk stratification of pediatric ependymoma patients - validation as an adverse prognostic marker in the German multicenter HIT2000 trial." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-lb-82.

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Stadler, Michael, Michael B. Schmitz, Wolfgang Laufer, and Peter Ragg. "Inverse Aeroacoustic Design of Axial Fans Using Genetic Optimization and the Lattice-Boltzmann Method." In ASME Turbo Expo 2013: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/gt2013-94501.

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The noise emitted by axial fans plays an integral role in product design. When conventional design procedures are applied, aeroacoustic properties are controlled via an extensive trial-and-error process. This involves building physical prototypes and performing acoustic measurements. In general, this procedure makes it difficult for a designer to gain an understanding of the functional relationship between noise and geometrical parameters of the fan. Hence, it is difficult for a human designer to control the aeroacoustic properties of the fan. To reduce the complexity of this process, we propo
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Kamali, Kaivan, Lijun Jiang, John Yen, and K. W. Wang. "Using Q-Learning and Genetic Algorithms to Improve the Efficiency of Weight Adjustments for Optimal Control and Design Problems." In ASME 2005 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/detc2005-85303.

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In traditional optimal control and design problems, the control gains and design parameters are usually derived to minimize a cost function reflecting the system performance and control effort. One major challenge of such approaches is the selection of weighting matrices in the cost function, which are usually determined via trial and error and human intuition. While various techniques have been proposed to automate the weight selection process, they either can not address complex design problems or suffer from slow convergence rate and high computational costs. We propose a layered approach b
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Gainer, John J., Levi D. DeVries, and Michael D. Kutzer. "Persistent Target Detection and Tracking by an Autonomous Swarm." In ASME 2018 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/detc2018-85573.

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This paper presents an autonomous multivehicle control algorithm capable of persistently searching and tracking targets in a defined search area subject to operational endurance constraints of individual agents. The algorithm development is modular to allow scalability and a control architecture that can be modified to any type of autonomous vehicle, search area, or target. In practical application, a target can be anything from heat signatures to radioactive material; therefore, this work employs a generic emitter-detector pair as a placeholder relationship for real world applications. The co
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Reports on the topic "Genetic gain trial"

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Cahaner, Avigdor, Sacit F. Bilgili, Orna Halevy, Roger J. Lien, and Kellye S. Joiner. effects of enhanced hypertrophy, reduced oxygen supply and heat load on breast meat yield and quality in broilers. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7699855.bard.

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Original objectivesThe objectives of this project were to evaluate the growth performance, meat yield and quality attributes of broiler strains widely differing in their genetic potential under normal temperature vs. warm temperature (short and long-term) conditions. Strain differences in breast muscle accretion rate, metabolic responses under heat load and, gross and histopathological changes in breast muscle under thermal load was also to be characterized. BackgroundTremendous genetic progress has been made in broiler chicken growth rate and meat yield since the 1950s. Higher growth rate is
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