Academic literature on the topic 'Genetic incompatibilities'

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Journal articles on the topic "Genetic incompatibilities"

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Bogdanova, Vera S. "Genetic and Molecular Genetic Basis of Nuclear-Plastid Incompatibilities." Plants 9, no. 1 (2019): 23. http://dx.doi.org/10.3390/plants9010023.

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Genetic analysis of nuclear-cytoplasm incompatibilities is not straightforward and requires an elaborated experimental design. A number of species have been genetically studied, but notable advances in genetic mapping of nuclear loci involved in nuclear-plastid incompatibility have been achieved only in wheat and pea. This review focuses on the study of the genetic background underlying nuclear-plastid incompatibilities, including cases where the molecular genetic basis of such incompatibility has been unveiled, such as in tobacco, Oenothera, pea, and wheat.
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Corbett-Detig, Russell B., Jun Zhou, Andrew G. Clark, Daniel L. Hartl, and Julien F. Ayroles. "Genetic incompatibilities are widespread within species." Nature 504, no. 7478 (2013): 135–37. http://dx.doi.org/10.1038/nature12678.

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Postel, Zoé, and Pascal Touzet. "Cytonuclear Genetic Incompatibilities in Plant Speciation." Plants 9, no. 4 (2020): 487. http://dx.doi.org/10.3390/plants9040487.

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Due to the endosymbiotic origin of organelles, a pattern of coevolution and coadaptation between organellar and nuclear genomes is required for proper cell function. In this review, we focus on the impact of cytonuclear interaction on the reproductive isolation of plant species. We give examples of cases where species exhibit barriers to reproduction which involve plastid-nuclear or mito-nuclear genetic incompatibilities, and describe the evolutionary processes at play. We also discuss potential mechanisms of hybrid fitness recovery such as paternal leakage. Finally, we point out the possible
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Presgraves, Daven C. "A Fine-Scale Genetic Analysis of Hybrid Incompatibilities in Drosophila." Genetics 163, no. 3 (2003): 955–72. http://dx.doi.org/10.1093/genetics/163.3.955.

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Abstract The sterility and inviability of species hybrids is thought to evolve by the accumulation of genes that cause generally recessive, incompatible epistatic interactions between species. Most analyses of the loci involved in such hybrid incompatibilities have suffered from low genetic resolution. Here I present a fine-resolution genetic screen that allows systematic counting, mapping, and characterizing of a large number of hybrid incompatibility loci in a model genetic system. Using small autosomal deletions from D. melanogaster and a hybrid rescue mutation from D. simulans, I measured
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Gadau, Jürgen, Robert E. Page, and John H. Werren. "Mapping of Hybrid Incompatibility Loci in Nasonia." Genetics 153, no. 4 (1999): 1731–41. http://dx.doi.org/10.1093/genetics/153.4.1731.

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Abstract According to theory, F2 hybrid breakdown (lethality or sterility) is due to incompatibilities between interacting genes of the different species (i.e., the breaking up of coadapted gene complexes). Detection of such incompatibilities is particularly straightforward in haplodiploid species, because virgin F1 hybrid females will produce haploid recombinant F2 males. This feature allows for screening of the complete genome for recessive genetic incompatibilities. Crosses were performed between Nasonia vitripennis (v) and its sibling species N. giraulti (g). First, a linkage map was produ
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Orr, H. A. "The population genetics of speciation: the evolution of hybrid incompatibilities." Genetics 139, no. 4 (1995): 1805–13. http://dx.doi.org/10.1093/genetics/139.4.1805.

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Abstract Speciation often results from the accumulation of "complementary genes," i.e., from genes that, while having no deleterious effect within species, cause inviability or sterility when brought together with genes from another species. Here I model speciation as the accumulation of genic incompatibilities between diverging populations. Several results are obtained. First, and most important, the number of genic incompatibilities between taxa increases much faster than linearly with time. In particular, the probability of speciation increases at least as fast as the square of the time sin
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Turelli, Michael, and H. Allen Orr. "Dominance, Epistasis and the Genetics of Postzygotic Isolation." Genetics 154, no. 4 (2000): 1663–79. http://dx.doi.org/10.1093/genetics/154.4.1663.

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Abstract The sterility and inviability of species hybrids can be explained by between-locus “Dobzhansky-Muller” incompatibilities: alleles that are fit on their “normal” genetic backgrounds sometimes lower fitness when brought together in hybrids. We present a model of two-locus incompatibilities that distinguishes among three types of hybrid interactions: those between heterozygous loci (H0), those between a heterozygous and a homozygous (or hemizygous) locus (H1), and those between homozygous loci (H2). We predict the relative fitnesses of hybrid genotypes by calculating the expected numbers
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Presgraves, Daven C. "Darwin and the Origin of Interspecific Genetic Incompatibilities." American Naturalist 176, S1 (2010): S45—S60. http://dx.doi.org/10.1086/657058.

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Martin, Noland H., and John H. Willis. "Geographical variation in postzygotic isolation and its genetic basis within and between two Mimulus species." Philosophical Transactions of the Royal Society B: Biological Sciences 365, no. 1552 (2010): 2469–78. http://dx.doi.org/10.1098/rstb.2010.0030.

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The aim of this study is to investigate the evolution of intrinsic postzygotic isolation within and between populations of Mimulus guttatus and Mimulus nasutus . We made 17 intraspecific and interspecific crosses, across a wide geographical scale. We examined the seed germination success and pollen fertility of reciprocal F 1 and F 2 hybrids and their pure-species parents, and used biometrical genetic tests to distinguish among alternative models of inheritance. Hybrid seed inviability was sporadic in both interspecific and intraspecific crosses. For several crosses, Dobzhansky–Muller incompat
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Sánchez-Ramírez, Santiago, Jörg G. Weiss, Cristel G. Thomas, and Asher D. Cutter. "Widespread misregulation of inter-species hybrid transcriptomes due to sex-specific and sex-chromosome regulatory evolution." PLOS Genetics 17, no. 3 (2021): e1009409. http://dx.doi.org/10.1371/journal.pgen.1009409.

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When gene regulatory networks diverge between species, their dysfunctional expression in inter-species hybrid individuals can create genetic incompatibilities that generate the developmental defects responsible for intrinsic post-zygotic reproductive isolation. Both cis- and trans-acting regulatory divergence can be hastened by directional selection through adaptation, sexual selection, and inter-sexual conflict, in addition to cryptic evolution under stabilizing selection. Dysfunctional sex-biased gene expression, in particular, may provide an important source of sexually-dimorphic genetic in
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Dissertations / Theses on the topic "Genetic incompatibilities"

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Malfant, Marine. "Divergence évolutive et isolement reproducteur chez les ascidies du genre Ciona, introduites et indigènes en Europe." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066640.

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Du fait de la complexité des processus de spéciation, l'étude des relations évolutives entre espèces nécessite une approche intégrative. Nous avons combiné croisements expérimentaux et études moléculaires (séquençage mitochondrial et RAD-seq) pour étudier les relations évolutives entre espèces indigènes et introduites du genre Ciona, en Europe. Nous avons examiné deux mécanismes post-zygotiques restant à explorer pour expliquer l'absence d'introgression de C. robusta et C. intestinalis dans leur zone de sympatrie en Manche : 1) la contre-sélection des hybrides par l'environnement (température
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Barragan, Lopez Ana Cristina [Verfasser]. "A Dangerous Mix : From Natural Variation to Genetic Incompatibilities in Arabidopsis thaliana and Arabidopsis arenosa / Ana Cristina Barragan Lopez." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1224232798/34.

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Duvaux, Ludovic. "Déterminants historiques et sélectifs des échanges génétiques au cours de la spéciation chez la souris domestique : patrons de coalescence et introgression en zone hybride." Thesis, Montpellier 2, 2010. http://www.theses.fr/2010MON20116/document.

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Afin de comprendre le processus de spéciation, il est nécessaire d'appréhender les patrons de flux géniques entre espèces naissantes et le rôle de la sélection dans leur détermination. C'est ce que tente d'aborder cette thèse en utilisant comme modèle deux sous-espèces de la souris domestique, Mus musculus. Nous avons reconstitué l'histoire de leur différenciation sur la base du polymorphisme de séquence à 60 locus autosomaux. La simulation du coalescent de ces locus sous plusieurs scenarios historiques nous a permis d'inférer, via une méthode ABC (Approximate Bayesian Computation), une diverg
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Bi, Yu. "Characterization of hybrid incompatibilities between caenorhabditis briggsae and C. sp. 9." HKBU Institutional Repository, 2014. https://repository.hkbu.edu.hk/etd_oa/86.

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Hybrid incompatibility (HI) refers to lethality, sterility and other reduction in fitness of hybrid progeny between related species which has been frequently observed in different taxa. Its mechanism has been generalized as the consequence of conflicts between genomes of the related species that have been subject to independent evolution. HI plays a critical role in speciation by reducing or preventing exchange of the genetic materials between related species, gradually leading to reproductive isolation. According to the widely accepted Dobzhansky-Muller model, HI is produced by incompatible e
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Ren, Xiaoliang. "Identification of loci/genes responsible for hybrid incompatibilities between Caenorhabditis briggsae and C. Nigoni." HKBU Institutional Repository, 2017. https://repository.hkbu.edu.hk/etd_oa/411.

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Identification of genetic basis of Hybrid Incompatibility (HI) in hybrids between closely related species leads to a comprehensive understanding of speciation. Although model organism C. elegans is well-established in laboratory, it has performed little contribution to this research area, because C. elegans failed to mate with other sister species and produce viable progeny. As a sister species of C. briggsae, which is close to C. elegans, newly discovered C. nigoni made it possible to identify the genetic basis of HI in nematode species. In this study, a new species pair including C. nigoni a
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Atanasov, Kostadin Evgeniev. "Genetics of natural variation and environmental modulation of immune-related hybrid incompatibilities in Arabidopsis." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/667030.

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Arabidopsis thaliana is a small ruderal weed with prominent north-hemisphere distribution. It has an autogamous style of reproduction, whereas about 3% of the natural population can exhibit outcrosses. Some of these outcrosses produce incompatible hybrids exhibiting temperature-dependent autoimmunity. The hybridization between accessions Ler (from North-Europe) and Kas-2 (from Central Asia) produces an incompatible hybrid. The genetics underlying the incompatibility is caused by the deleterious epistasic interactions between a unique Ler haplotype of RPP1-like genes and the SRF3 Kas-2 receptor
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Vayssade, Chloé. "Interaction entre démographie et génétique dans les petites populations : études sur un Hyménoptère parasitoïde avec incompatibilités génétiques." Phd thesis, Université Nice Sophia Antipolis, 2014. http://tel.archives-ouvertes.fr/tel-00960320.

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L'interaction de processus génétiques et démographiques peut générer des vortex d'extinction. Chez les Hyménoptères, les mâles sont haploïdes et les femelles diploïdes. Chez les espèces avec sl-CSD (single-locus complementary sex determination), les haploïdes, se développent en mâles et les diploïdes hétérozygotes au gène du CSD, en femelles. Les diploïdes homozygotes sont des mâles non viables ou stériles. Des études théoriques suggèrent que la production de mâles diploïdes peut entraîner les petites populations d'Hyménoptères dans un vortex d'extinction. Le premier objectif est d'encourager
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Montanari, Sara. "Identification and mapping of genomic regions controlling fire blight and psylla resistance and hybrid necrosis in pear." Thesis, Angers, 2015. http://www.theses.fr/2015ANGE0063/document.

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Le feu bactérien et le psylle causent d’importantes pertes économiques dans les zones de production du poirier dans le monde entier. Le développement de nouvelles variétés de poirier résistantes à ces bio-agresseurs constitue un enjeu majeur dans le cadre d’un programme de lutte intégrée. L’objectif de ce projet de thèse est l'étude du déterminisme génétique de la résistance vis-à-vis de ces deux bio-agresseurs. La thèse a été réalisée dans le cadre d’une collaboration internationale entre Fondazione Edmund Mach (Italie), Institut de Recherches en Horticulture et Semences (France) et Plant &am
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Magnin, Michel. "Resistance aux insecticides organophosphores : detection, caracterisation genetique et dynamique dans les populations naturelles : etude dans le complexe culex pipiens l. (diptera : culicidae) et essai d'application a simulium damnosum s.l. theobald." Paris 6, 1986. http://www.theses.fr/1986PA066513.

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Le protocole d'etude mis au point sur le modele de la resistance du moustique culex pipiens aux insecticides organophosphores dans le sud de la france, a permis de preciser la distribution des genes est-3**(a), codant pour une esterase de detoxication de grande activite, et ace**(r), codant pour une acetylcholinesterase moins sensible a l'inhibition par l'insecticide, ainsi que de caracteriser une nouvelle esterase de grande activite (est-4), egalement associee a la resistance. Ce protocole a ete egalement utilise pour etudier les mecanismes de resistance de c. Quinquefasciatus et de simulium
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Tulchinsky, Alexander Y. "Evolution of hybrid incompatibilities in gene regulatory networks." 2013. https://scholarworks.umass.edu/dissertations/AAI3603167.

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Under the Dobzhansky-Muller model, postzygotic isolation results from incompatibility between interacting genes. Evidence points to regulatory networks as a rich source of incompatibilities that impact hybrid fitness. Pleiotropy is a natural feature of regulatory networks because regulatory elements generally have multiple targets. Both pleiotropy and hybrid incompatibility arise due to genetic interactions; therefore we can expect an intimate association between them. In the following chapters, I investigate the relationship between pleiotropy and hybrid incompatibility in the context of regu
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Book chapters on the topic "Genetic incompatibilities"

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Lawler, S. D. "AB0 and HLA Systems: Effects of Maternal Incompatibilities on the Conceptus." In Human Genetics. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71635-5_30.

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Allendorf, Fred W., W. Chris Funk, Sally N. Aitken, Margaret Byrne, and Gordon Luikart. "Genetic Variation in Natural Populations." In Conservation and the Genomics of Populations. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198856566.003.0003.

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Genetic variation among individuals within populations and among populations can be assessed at the chromosomal, protein, or DNA sequence level. The best tool or approach depends on the question being asked. Variation in the number or structure of chromosomes can result in reproductive incompatibilities and reduced fitness that influences the success of conservation efforts. Differences in amino acid sequence that alter the electrophoretic mobility of proteins, termed allozymes, were widely used to measure genetic variation and population differentiation on a gene-by-gene basis prior to advances in DNA sequencing. Mitochondria and chloroplasts contain circular DNA molecules that are usually inherited from one parent and are useful for assessing population history and structure. Most studies of genetic variation now rely on the analysis of single nucleotide polymorphisms (SNPs)—variations in nucleotides at a single location within the genome—to understand both selectively neutral and adaptive processes.
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Hartl, Daniel L. "Complex Traits in Natural Populations." In A Primer of Population Genetics and Genomics. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198862291.003.0009.

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This chapter could as well be titled “Population Genomics,” although many aspects of population genomics are integrated throughout the other chapters. It includes estimates of mutational variance and standing variance, phenotypic evolution under directional selection as measured by the linear selection gradient, and phenotypic evolution under stabilizing selection. It explores the strengths and limitations of genome-wide association studies of quantitative trait loci (QTLs) and expression (eQTLs) to detect genetic influencing complex traits in natural populations and genetic risk factors for complex diseases such as heart disease or diabetes. The number of genes affecting complex traits is considered, as well as evidence bearing on the issue of whether complex diseases are primarily affected by a very large number of genes, almost all of small effect, and how this bears on direct-to-consumer and over-the-counter genetic testing. The population genomics of adaptation is considered, including drug resistance, domestication, and local selection versus gene flow. The chapter concludes with the population genomics of speciation as illustrated by reinforcement of mating barriers, the reproducibility of phenotypic and genetic changes, and the accumulation of genetic incompatibilities.
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Gregory, Lau. "Rhesus and Other Fetomaternal Incompatibilities." In Emery and Rimoin's Principles and Practice of Medical Genetics. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-383834-6.00078-1.

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Lalezari, Parviz, and Behnaz Bayat. "Neutrophil-Specific Antigens: Immunobiology, Genetics and Roles in Clinical Disorders." In Blood Groups - More Than Inheritance of Antigenic Substances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102431.

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Neutrophils are the most abundant nucleated cells in blood circulation and play important roles in the innate and adaptive immune responses. Neutrophil-specific antigens, only expressed on neutrophils, are glycoproteins originally identified in studies on neonatal neutropenia due to fetal-maternal incompatibility and autoimmune neutropenia of infancy. The most investigated neutrophil–specific antigens are the NA and NB antigens that their incompatibilities also cause transfusion-induced febrile reactions and acute lung injury, a potentially fatal reaction, and in bone marrow transplantation, causing graft rejection. NA antigens are members of the immunoglobulin superfamily and are low-affinity Fc-receptors FcγRIIIb (CD16b). Fc receptors connect the F(ab), the antigen-binding fragment of the antibody molecules, to neutrophils and lead them to recognize and phagocytize the targeted antigens. The NB (CD177) antigen belongs to the urokinase-type Plasminogen Activator Receptor Superfamily (uPAR, CD59, Ly6), but its specific functions have not been fully determined. It is known, however, that NB antigen binds proteinase-3 (PR3 to the neutrophil membrane), a serine protease. In clinical studies, it was also demonstrated that NB expression is highly elevated in Polycythemia Vera and is unexpectedly expressed in some cancer tissues. Neutrophil-specific antigens are examples of antigens that have important biological and clinical activities beyond antigenicity.
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Conference papers on the topic "Genetic incompatibilities"

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Roth, Bryce, and Chirag Patel. "Application of Genetic Algorithms in the Engine Technology Selection Process." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38482.

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The objective of this paper is to demonstrate the application of Genetic Algorithms to the engine technology selection process. The “Technology Identification, Evaluation, and Selection” method is discussed in conjunction with Genetic Algorithm optimization as a technique to quickly evaluate the impact of various technologies and select the subset with the highest potential payoff. Techniques used to model various aspects of engine technologies are described, with emphasis on technology constraints and their impact on the combinatorial optimization of technologies. Challenges include objective
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