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Relevant bibliographies by topics / Genetic makeup / Dissertations / Theses

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Dissertations / Theses on the topic 'Genetic makeup'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Nadeu, Prat Ferran. "Genomic determinants of chronic lymphocytic leukemia progression: from individual drivers to a heterogeneous genetic makeup." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/669770.

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Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia in Western countries. Although the disease might follow an indolent course, it rapidly progresses in a fraction of cases, become resistant to treatment, and eventually transform to a more aggressive B-cell lymphoma, known as Richter syndrome. The mechanisms underlying these distinct clinical courses are not fully understood. In this Thesis, we aimed to elucidate the genomic determinants of CLL progression, to provide tools to characterize these tumors from next-generation sequencing data, and to extract key biological

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2

Peters, Eric. "The pharmacogenetics of antidepressant response moving towards individualized therapy ; improving patient outcomes through optimization of treatment based on genetic makeup." Saarbrücken VDM Verlag Dr. Müller, 2007. http://d-nb.info/989451372/04.

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3

Shojaei, Saadi Habib Allah, and Saadi Habib Allah Shojaei. "Development and application of sensitive genome-wide platforms to study the genetic and epigenetic (DNA methylation) makeup of gametes and early bovine embryos." Doctoral thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/27012.

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Pour ce projet, nous avons développé une plateforme pour l’analyse pangénomique de la méthylation de l’ADN chez le bovin qui est compatible avec des échantillons de petites tailles. Cet outil est utilisé pour étudier les caractéristiques génétiques et épigénétiques (méthylation de l'ADN) des gamètes soumis aux procédures de procréation médicalement assisitée et des embryons précoces. Dans un premier temps, une plateforme d’analyse de biopuces spécifiques pour l’étude de la méthylation de l’ADN chez l’espèce bovine a été développée. Cette plateforme a ensuite été optimisée pour produire des ana

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4

O'Connor, Ellen Therese. "What makes a pathogen? genetic and structural heterogeneity of neisserial lipooligosaccharide /." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/3359.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2006.<br>Thesis research directed by: Cell Biology & Molecular Genetics. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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5

Ekelund, Martin, and Erik Pettersson. "Make or buy? : Developing a generic framework for make-or-buy decisions at Cardo AB." Thesis, Linköping University, Logistics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-57288.

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<p>Cardo AB is an international corporate group that has performed major organizational changes the last few years. These changes utilize possible synergies that exist in a corporate group. One of the initiatives is that Cardo wants to develop a model for make-or-buy decisions. Therefore, the purpose of this thesis is stated as:</p><p><em>The study’s purpose is to develop a generic model for make-or-buy decisions at Cardo.</em></p><p>To develop the model, a theoretical study was conducted, where four main aspects were identified: core capability, risk, cost and relationship. For each aspect, a

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6

Candido, Marco Antonio Barbosa. "A hybrid genetic approach to solve real make-to-order job shop scheduling problems." reponame:Repositório Institucional da UFSC, 1997. https://repositorio.ufsc.br/xmlui/handle/123456789/158165.

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Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnologico<br>Made available in DSpace on 2016-01-08T22:12:41Z (GMT). No. of bitstreams: 1 107336.pdf: 3622415 bytes, checksum: 953f1623eaa5c472c4fa60df73f7c69d (MD5) Previous issue date: 1997<br>Procedimentos de busca local (ex. busca tabu) e algoritmos genéticos têm apresentado excelentes resultados em problemas clássicos de programação da produção em ambientes job shop. No entanto, estas abordagens apresentam pobres habilidades de modelamento e poucas aplicações com restrições de ambientes reais de produção têm sido public

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7

Makewita, Sumedha M. "Investigating the generic information seeking function of organisational decision makers : perspectives on improving organisational information systems." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246832.

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8

Phenix, Hilary. "Derivation and Use of Gene Network Models to Make Quantitative Predictions of Genetic Interaction Data." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/37031.

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This thesis investigates how pairwise combinatorial gene and stimulus perturbation experiments are conducted and interpreted. In particular, I investigate gene perturbation in the form of knockout, which can be achieved in a pairwise manner by SGA or CRISPR/Cas9 methods. In the present literature, I distinguish two approaches to interpretation: the calculation of stimulus and gene interactions, and the identification of equality among phenotypes measured for distinct perturbation conditions. I describe how each approach has been applied to derive hypotheses about gene regulatory networks. I id

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9

Cheng, Wenting. "China: Rule-taker or Rule-maker in the International Intellectual Property System?" Phd thesis, Canberra, ACT : The Australian National University, 2018. http://hdl.handle.net/1885/148161.

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Intellectual property has been a crucial issue for China in the past four decades. Internationally, it was central to China’s fifteen-year negotiation on its accession to the WTO and has been a priority in China-US bilateral relations. Domestically, changes in the regulation and use of intellectual property reflect a larger picture of rapid economic and social transition in China. Initially, China was a rule-taker in intellectual property, experiencing pressure from abroad to do much more on intellectual property. In response, China enacted comprehensive domestic intellectual property laws. Fr

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10

Allard, David M. "A Multi-Objective Genetic Algorithm to Solve Single Machine Scheduling Problems Using a Fuzzy Fitness Function." Ohio University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1180968613.

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11

Raymond, Victoria M. "Taking a Step Back to Make a Leap Forward: A Qualitative Survey of Underrepresented Minority Genetic Counselors." Cincinnati, Ohio : University of Cincinnati, 2006. http://www.ohiolink.edu/etd/view.cgi?acc_num=ucin1148308555.

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Thesis (M.S.)--University of Cincinnati, 2006.<br>Advisor: Dr. Nancy Steinberg Warren. Title from electronic thesis title page (viewed June 5, 2009). Includes abstract. Keywords: Minority; minority recruitment; genetic counseling; health disparities; barriers; characterization; African American; Native American; Hispanic. Includes bibliographical references.

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12

Pogson, Delia. "How individuals who may have concerns about a family history of breast cancer make sense of genetic information." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/359001/.

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An individual’s personal experience may lead them to start to think about their own family history, to wonder if they might have inherited a genetic risk of breast cancer and start to consider the scientific genetic information. The focus for this research is how individuals make sense of genetic information and has been undertaken with members of the general population before they come into contact with specialist services. There are clear limitations in the literature addressing the focus of this research, including the population sampled - individuals before they come into contact with serv

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13

Pazuniak, Orest V. "Do Labels Make A Difference: Estimating The Impacts Of Vermont’s Gmo Labeling Law On Perceptions And Prices." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/974.

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Vermont is the first and only state in the US to establish mandatory labels for food containing genetically modified organisms (GMOs). This thesis investigates the impact of the mandatory labeling law as it relates to changes in prices, quantities sold, and opinions of GMOs. First, grocery store scanner data from Vermont and Oregon are compared using triple difference (difference-in-difference-in-difference) models. Next, Vermont, Oregon, and Colorado survey response data are compared using difference-in-difference models. The findings reveal that there is a general price premium for non-GMO g

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14

Baudot, Matthias. "Rôle des canaux ioniques dans les dysfonctions de l'activité du nœud sinusal." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTT063/document.

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L’automatisme cardiaque est généré par un mécanisme fondamental partiellement compris et controversé, initié par des cardiomyocytes spécialisés dans le nœud sino-atrial (NSA). Ces cellules pacemaker (cNSA) présentent une phase spontanée de dépolarisation diastolique (DD), qui mène le potentiel de membrane de la fin de la repolarisation du potentiel d’action (PA) au seuil de déclenchement du PA suivant. Cette activité spontanée implique plusieurs canaux ioniques à la surface de la membrane plasmique et la dynamique calcique intracellulaire. Les cardiomyocytes contractiles du myocarde expriment

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15

Debarba, Rômulo João. "Estudos de diferentes métodos de melhoramento de pastagens no Alto Vale do Itajaí-SC Brasil, utilizando as leguminosas maku (Lotus uliginosus Schkuhr) e amendoim forrageiro (Arachis pintoi Kraprov." Florianópolis, SC, 2006. http://repositorio.ufsc.br/xmlui/handle/123456789/88689.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-Graduação em Agroecossistemas.<br>Made available in DSpace on 2012-10-22T12:27:25Z (GMT). No. of bitstreams: 1 234075.pdf: 2570300 bytes, checksum: 8c27b0453f67f3f707a283607fcb7fef (MD5)<br>A região do Vale do Itajaí já foi uma das maiores produtoras de leite do Estado, chegando a ter uma média de produção de 2000 L/vaca/ano. A produção de leite a nível de Estado vem sofrendo incrementos, mas o número de produtores tem decaído ano após ano devido aos custos elevados de produção, princ

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16

Yoo, Julie Keunhee. "What makes personalized medicine work? : an empirical analysis of the role of product attributes, medical professional societies and patient groups in the diffusion of four breast cancer genetic tests." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54595.

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Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 69-73).<br>Personalized medicine is the science and practice of customizing medical screening and treatment plans for an individual based on his or her genomic profile. Breast cancer is one of the first disease areas to serve as an example of this approach, where most patients have experienced its benefits through the use of genetic tests that provide decision support for health care workers regarding the likely effectiveness of specif

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17

Anusontpornperm, Somchai. "Land evaluation using soil properties in relation to genesis and classification to make guidance on soil management for cassava crop practice." Thesis, University of Reading, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413676.

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18

Call, Brandon R. "Obstacle Avoidance for Small Unmanned Air Vehicles." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1556.pdf.

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19

PILLAI, Vinoshene. "Intravital two photon clcium imaging of glioblastoma mouse models." Doctoral thesis, Scuola Normale Superiore, 2021. http://hdl.handle.net/11384/109211.

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20

Barreto, Hugo Manuel Condessa 1990. "Deciphering the genetic makeup of the Bacillus subtillis Esat-6-like secretion system." Master's thesis, 2013. http://hdl.handle.net/10451/9636.

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Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2013<br>The locus yukEDCByueBC of the Gram-positive model bacterium Bacillus subtilis was recently shown to encode a functional Esat-6-like secretion system (Ess), in natural isolates of this bacterium, with YukE being a typical secretion substrate of the WXG100 superfamily. This genetic locus has been renamed BsEss. Type VII/Ess secretion systems are widespread among bacteria of the phyla Actinobacteria and Firmicutes and in some species they play an important role in bacterial pathogenesis, as

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21

Botas, Bruna Patrícia Marques. "Edição Genética em Embriões Humanos - A Responsabilidade Civil Médica No Contexto da Terapia Génica Germinal." Master's thesis, 2021. http://hdl.handle.net/10316/97516.

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Dissertação de Mestrado em Direito apresentada à Faculdade de Direito<br>O mundo tem vindo a assistir grandes desenvolvimentos no domínio da genética e medicina reprodutiva, passando-se a falar da “Revolução GNR (Genética, Nanotecnologia e Robótica)”, capaz de promover a saúde e qualidade de vida humana, como nunca antes. O avanço que maior destaque tem tido na comunidade científica e que será aqui objeto de estudo, insere-se no contexto da Engenharia genética, com o surgimento da tecnologia CRISPR/Cas com potencialidade de corrigir, substituir e modificar o genoma humano, de forma rápida e pr

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Guerrero, J. David. "Can genetic technology make having a child immoral?" 2004. http://hdl.handle.net/1993/16269.

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23

Lai, Chien-Ting, and 賴建廷. "Evaluation of Genetic Variation with Inter Simple Sequence Repeat DNA Makers and Analysis of Camptothecin Contain with High Performance Liquid Chromatography for Nothapodytes foetida Sleumer." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/41548443103600600067.

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碩士<br>國立嘉義大學<br>生物科技研究所<br>94<br>The plant Nothapodytes foetida （Wight） Sleumer belongs to genus Nothapodyes Blume (Icacinaceae）. It contains with high value of camptothecin in Taiwan. Cultural type in Taiwan is become outlook variation. The study elucidated the population genetic variation among the different region in Taiwan. An ISSR (Inter-Simple Sequence Repeat) analysis is used to figure out genetic variation. The contain of camptothecin was also analyzed by HPLC（High pressure liquid chromatography）for Orchid Island type Nothapodytes foetida Sleumer. In the experiment, 12 ISSR primers wer

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24

SMAGADI, Aphrodite. "The utilization of natural plant genetic resources and benefit-sharing for the production and legal protection of medicines : the impact of the implementation of the convention on biological diversity." Doctoral thesis, 2006. http://hdl.handle.net/1814/6597.

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Defence date: 14 November 2006<br>Examining board: Prof. Ernst-Ulrich Petersmann (Supervisor, European University Institute) ; Prof. Francesco Francioni (European University Institute) ; Prof. Thomas Cottier (University of Bern, Switzerland) ; Dr. Graham Dutfield (Queen Mary, University of London)<br>PDF of thesis uploaded from the Library digitised archive of EUI PhD theses completed between 2013 and 2017

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