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Dissertations / Theses on the topic 'Genetic organisation of yeast'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Owuama, C. I. "Genetic transformation of Saccharomyces cerevisiae with chimaeric plasmids." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381362.

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2

Alfredsson, Timmins Jenny. "Functional organisation of the cell nucleus in the fission yeast, Schizosaccharomyces pombe." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107283.

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3

Mirza, Memona. "Genetic recombination in yeast." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357567.

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4

Bird, Louise E. "Genetic engineering of brewing yeast." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259783.

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5

Reynolds, Nicola C. "Genetic manipulation of yeast strains." Thesis, University of Greenwich, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276133.

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6

Kirkham, Jennifer Ann. "The genetic improvement of brewing yeast." Thesis, Cranfield University, 1989. http://dspace.lib.cranfield.ac.uk/handle/1826/10382.

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Brewing yeast strains are usually aneuploid or polyploid with no true mating type. Thus many of the techniques which can be used to genetically modify laboratory yeast strains cannot be applied to them. This study was aimed at developing the technology for the genetic modification of brewing yeasts towards producing genetically improved brewing strains, suitable for use in large scale beer production. A system has been developed which can produce brewing yeast transformants with high genetic stability and unimpaired brewing performance. Such transformants contain only the required extra geneti

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7

Dichtl, Bernhard. "Genetic analysis of yeast RNase MRP." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/13645.

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RNase MRP is a ribonucleoprotein particle (RNP) with endoribonucleolytic activity which is involved in the processing of pre-rRNA at site A<SUB>3</SUB>. A genetic screen for mutants which are synthetic lethal (sl) with a temperature sensitive (ts) mutation in the RNA component of RNase MRP (<I>rrp2-1</I>) has been performed in order to identify new gene products which physically and/or functionally interact with RNase MRP. Analysis of the obtained sl mutant strains led to the identification of a new and essential gene, <I>POP3</I>. Depletion of Pop3p <I>in vivo</I> results in a phenotype chara

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8

Zheng, Jie. "Genetic analysis of RNA silencing in yeast." Thesis, Queen Mary, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430880.

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9

Wenzlau, Janet Marie. "Mobile genetic elements in yeast mitochondrial DNA /." The Ohio State University, 1989. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487672631600712.

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10

Spira, Felix. "Spatio-temporal organisation of plasma membrane proteins in budding yeast." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-154960.

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11

Tai-Wong, Sue Mei. "Origin and genetic manipulation of brewing lager yeast." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249282.

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12

Smith, Victoria. "A molecular genetic analysis of yeast chromosome IX." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239206.

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13

Kennedy, Brian Keith. "Genetic and molecular analysis of aging in yeast." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/38813.

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14

Cheng, George. "Uncovering the genetic organisation of Claroideoglomus candidum." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-392016.

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Arbuscular mycorrhizal (AM) fungi are hypothesized to have been key players in facilitating thetransition from aquatic to terrestrial plants and continue to benefit plants through their symbioticassociation after 450 million years. These fungi form mycelia that can contain hundreds of nucleiwithin one aseptate cytoplasm, which leads to the ongoing debate on whether thesemultinucleated fungi are homokaryotic or heterokaryotic. Not only is there evidence to supportthe hypothesis of the nuclei as genetically identical, but also the other hypothesis of divergentnuclei within a single strain. There

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15

Yip, Hopi, of Western Sydney Hawkesbury University, and Faculty of Science and Technology. "Genetic manipulation of baker's yeast for improved maltose utilisation." THESIS_FSTA_SFS_Yip_H.xml, 1999. http://handle.uws.edu.au:8081/1959.7/223.

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Two yeast/E.coli shuttle vector plasmids were studied in 1994, termed pIBIDB and pBP33. According to this study, each plasmid should contain at least one ADH2UAS (upstream activation sequence in the alcohol dehydrogenase 2 gene) insert. In the present study, the constructed plasmids were analysed and transformed into laboratory strain yeast. The aim of this project was to identify the orientation, quantity and quality of the insert in the selected plasmids. Methods such as restriction analysis, polymerase chained reaction (PCR), sequencing, plate assays and enzyme assays were used to identify

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16

Dolan, William P. "Molecular genetic analysis of the fission yeast hsk1⁺ kinase /." Diss., Connect to a 24 p. preview or request complete full text in PDF formate. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3189214.

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17

Yip, Hopi. "Genetic manipulation of baker's yeast for improved maltose utilisation /." [Richmond, N.S.W.] : Centre for Biostructural and Biomolecular Resarch, Faculty of Science and Technolocy, University of Western Sydney, Hawkesbury, 1999. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030625.100807/index.html.

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18

Dishart, Kate Louise. "A genetic analysis of maltotriose transport in brewer's yeast." Thesis, Heriot-Watt University, 2000. http://hdl.handle.net/10399/569.

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19

Duarte, Julio Antonio Bargao. "Genetic and biochemical analysis of translational fidelity in yeast." Thesis, University of Kent, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.256999.

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20

Firoozan, Mandana. "Genetic and physiological control of translational fidelity in yeast." Thesis, University of Kent, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304734.

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21

Gleeson, Martin Antony Gerrard. "The genetic analysis of the methylotrophic yeast Hansenula polymorpha." Thesis, University of Sheffield, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328975.

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22

Kabbani, Nazir. "Chemical-genetic profiling of platelet-activating factor in yeast." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28189.

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The basic biological processes between the yeast Saccharomyces cerevisiae and mammals are highly conserved. Yeast posses many genes that are implicated in human diseases and have been successfully used as a model for the study of neurodegeneration. Platelet-Activating Factor (C16:0 PAF) causes neuronal cell death independent of its receptor and has been implicated in Alzheimer's disease. I hypothesized that yeast could be used as a model system for deciphering PAF receptor-independent signalling and have utilized genome-wide chemical genomic screening in yeast to further characterize the mole

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23

Heydari, Jonathan. "Bayesian hierarchical modelling for inferring genetic interactions in yeast." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2464.

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Identifying genetic interactions for a given microorganism, such as yeast, is difﬁcult. Quantitative Fitness Analysis (QFA) is a high-throughput experimental and computa tional methodology for quantifying the ﬁtness of microbial cultures. QFA can be used to compare between ﬁtness observations for different genotypes and thereby infer genetic interaction strengths. Current “naive” frequentist statistical approaches used in QFA do not model between-genotype variation or difference in genotype variation under differ ent conditions. In this thesis, a Bayesian approach is introduced to evaluate hie

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24

Fahmi, Zahra. "Study of 3D genome organisation in budding yeast by heterogeneous polymer simulations." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287470.

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Investigating the arrangement of the packed DNA inside the nucleus has revealed the essential role of genome organisation in controlling genome function. Furthermore, genome architecture is highly dynamic and significant chromatin re-organisation occurs in response to environmental changes. However, the mechanisms that drive the 3D organisation of the genome remain largely unknown. To understand the effect of biophysical properties of chromatin on the dynamics and structure of chromosomes, I developed a 3D computational model of the nucleus of the yeast S. cerevisiae during interphase. In the

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25

Wilson, J. M. "Protoplast-mediated genetic manipulation of brewing yeasts." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355426.

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26

Schoeman, Heidi. "The fate of genetically modified yeast in the environment." Thesis, Stellenbosch : Stellenbosch University, 2005. http://hdl.handle.net/10019.1/50489.

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Dissertation (PhD(Agric))--University of Stellenbosch, 2005.<br>ENGLISH ABSTRACT: Considerable efforts have been made to improve strains of the wine yeast Saccharomyces cerevisiae through the use of genetic engineering. Although the process is well defined, globally there is much resistance towards the use of genetically modified organisms (GMOs), primarily because little is known about their environmental fate and their potential effect on naturally occurring organisms. The public concern is mainly focused on the uncertainty associated with the impact of the deliberate or accidental re

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27

Wegrzyn, Renee Diane. "Genetic, biochemical, and physiological study of yeast prion protein aggregation." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/25221.

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28

Harrison, Richard. "Exploring environmentally-dependent genetic variation in the yeast Saccharomyces cerevisiae." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495742.

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Genetic variation is the raw material upon which natural selection acts to spread advantageous phenotypic traits throughout populations. Studies in the yeast Saccharomyces cerevisiae have begun to uncover the extent of genetic variation within yeast populations, but the fitness effects of this variation are still poorly understood. Furthermore, the interplay between genotype, envkonment and fitness only recently begun to be explored at the molecular level. The aun of this thesis is to explore this complex relationship.

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29

Van, Rooyen Ronel 1976. "Genetic engineering of the yeast Saccharomyces cerevisiae to ferment cellobiose." Thesis, Stellenbosch : Stellenbosch University, 2007. http://hdl.handle.net/10019.1/19455.

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Dissertation (PhD)--Stellenbosch University, 2007.<br>PCT patent registered: https://www.google.com/patents/WO2009034414A1?cl=en&dq=pct/ib2007/004098&hl=en&sa=X&ei=b7AxUsSZK4jB0gWi14HgCQ&ved=0CEkQ6AEwAg USA: https://www.google.com/patents/US20110129888?dq=pct/ib2007/004098&ei=b7AxUsSZK4jB0gWi14HgCQ&cl=en<br>USA patent registered: https://www.google.com/patents/US20110129888?dq=pct/ib2007/004098&ei=b7AxUsSZK4jB0gWi14HgCQ&cl=en<br>ENGLISH ABSTRACT: The conversion of cellulosic biomass into fuels and chemicals has the potential to positively impact the South African economy, but is reliant on

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30

La, Grange Daniel Coenrad. "Genetic engineering of the yeast Saccharomyces cerevisiae to degrade xylan." Thesis, Stellenbosch : University of Stellenbosch, 1999. http://hdl.handle.net/10019.1/8490.

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Thesis (PhD)--University of Stellenbosch, 1999.<br>ENGLISH ABSTRACT: Hemicellulose, consisting mainly of xylan, ranks after cellulose, as the most abundant group of renewable polysaccharides in agricultural biomass. Xylan is a complex polymer consisting of a β D 1,4 linked xylopyranoside backbone, which may contain substituents. Enzymatic hydrolysis of xylan involves the action of a number of different hydrolytic enzymes. The yeast Saccharomyces cerevisiae has been used extensively in traditional food and beverage processes (baking, brewing and winemaking), as well as for the production of

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31

Bossier, Ana M. Martins. "Genetic manipulation of tryptophan biosynthesis in the yeast Saccharomyces cerevisiae." Thesis, University of Kent, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279705.

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32

Thompson, Craig Marshall. "Molecular genetic analysis of a yeast RNA polymerase II holoenzyme." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/33524.

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33

Ramage, Anne Donaldson. "Genetic analysis of mutations affecting the initiation of yeast sporulation." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/16922.

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The spd (sporulation derepressed) mutants of Saccharomyces cerevisiae appear to have lost some of the nitrogen source repression of sporulation but remain subject to glucose repression. In media containing acetate, glycerol or pyruvate as the sole carbon source, these mutants sporulate profusely, a phenotype referred to as hypersporulation (Dawes and Calvert, 1984). This hypersporulation phenotype is also characteristic of mutants in the cAMP signal pathway which have low intracellular levels of cAMP e.g. cdc25, ras2, cdc35, yet the spdl mutants are not allelic to any of these genes. A 4.8 kb

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34

Eder, Matthias. "Deciphering the genetic and metabolic basis of yeast aroma properties." Thesis, Montpellier, SupAgro, 2017. http://www.theses.fr/2017NSAM0054.

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La levure Saccharomyces cerevisiae joue un rôle essentiel dans la production de composés aromatiques, tels que les esters, les alcools supérieurs et les acides organiques, ainsi que dans la transformation de précurseurs d'arômes du raisin pendant la fermentation du vin. Afin d'identifier les bases génomiques et métaboliques de ces propriétés, un croisement a été réalisé entre deux souches de levures de vin, sélectionnées pour leurs besoins en azote différents lors de la fermentation. 130 ségrégants de génération F2 ont été génotypés par séquençage complet du génome et individuellement phénotyp

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35

Fournier, Téo. "Unraveling the genetic architecture of traits in natural yeast populations." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ073.

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Comprendre les règles contrôlant la diversité entre individus issus d’une même population est l’un des points centraux de la biologie moderne. Récemment, l'avènement des études d’association pan-génomique a permis de lier le génotype au phénotype au sein de populations. Cependant, une part importante de la variance phénotypique reste inexpliquée et est appelée héritabilité manquante. En combinant le modèle d’étude Saccharomyces cerevisiae, un design emprunté à la génétique classique et des stratégies de phénotypage et de génotypage à haut-débit, ce travail a pour objectif d’élargir notre compr

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36

James, Allan. "A genetic analysis of sulfate transporters in Saccharomyces cerevisiae and Saccharomyces pastorianus." Thesis, Heriot-Watt University, 2000. http://hdl.handle.net/10399/1525.

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37

Cai, Chunhui. "Identification and characterization of yeast synergistic regulatory interaction from high throughput data." HKBU Institutional Repository, 2010. http://repository.hkbu.edu.hk/etd_ra/1190.

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38

Gong, He. "Studies of genetic factors modulating polyglutamine toxicity in the yeast model." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/42796.

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Polyglutamine-expanded fragments, derived from the human huntingtin protein, are aggregation-prone and toxic in yeast cells, bearing endogenous QN-rich proteins in the aggregated (prion) form. Attachment of the proline-rich region targets polyglutamine aggregates to the large perinuclear deposit (aggresome). Aggresome targeting ameliorates polyglutamine cytotoxicity in the presence of the prion form of Rnq1 protein, however, aggresome-forming construct remains toxic in the presence of the prion form of translation termination (release) factor Sup35 (eRF3). Disomy by chromosome II partly ameli

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39

González, Sánchez Beatriz. "Filamentous growth in wine yeast: signal triggering and genetic factors involved." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/461060.

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Els compostos derivats d’aminoàcids aromàtics, presents de manera natural al most, són transformats pel metabolisme del llevat. En aquesta tesi, estudiem la producció d’aquests compostos en most sintètic amb diferent contingut en nutrients, per llevats del vi. Els resultats mostren que el patró de síntesi de triptofol, tirosol i fenilethanol és controlat per la disponibilitat de nutrients. A més, analitzem l’efecte d’aquests i més compostos derivats dels aminoàcids aromàtics sobre el creixement i la morfologia cel·lular del llevat. Com a resultats, observem que la filamentació induïda per etan

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40

Fransson, Martin. "Identification of a Genetic Network in the Budding Yeast Cell Cycle." Thesis, Linköping University, Department of Electrical Engineering, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2389.

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<p>By using AR/ARX-models on data generated by a nonlinear differential equation system representing a model for the cell-cycle control system in budding yeast, the interactions among proteins and thereby also to some extent the genes, are sought. A method consisting of graphical analysis of differences between estimates from two local linear models seems to make it possible to separate a set of linear equations from the nonlinear system. By comparing the properties of the estimations in the linear equations a set of approximate equations corresponding well to the real ones are found. </p><p>A

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41

Morlon, Elodie. "Novel yeast genetic approaches to isolating Arabidopsis polyamine transport-related genes." Thesis, University of East Anglia, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393126.

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42

Austriaco, Nicanor Robles 1968. "UTH1 and the genetic control of aging in the yeast, Saccharomyces." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/38812.

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43

Johns, Alexander Michael Bedford. "Molecular genetic tools for manipulation of the oleaginous yeast Rhodotorula toruloides." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/27981.

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Rhodotorula (Rhodosporidium) toruloides is an oleaginous basidiomycete yeast with great biotechnological potential. Capable of accumulating lipid up to 76 % of its dry biomass and well suited to the metabolism of lignocellulosic hydrolysate, it is a good candidate for production of advanced biofuels as well as a host of other potential roles in industry. However, molecular genetic tools for manipulation of this yeast are lacking and its high genomic GC content can make routine cloning difficult. Agrobacterium tumefaciens-mediated transformation of R. toruloides CBS 14 was demonstrated, and pla

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44

Donald, Kenneth Allen Gordon. "Genetic and biochemical studies of mitochondria in the yeast Saccharomyces cerevisiae." Thesis, University of Warwick, 1991. http://wrap.warwick.ac.uk/108880/.

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Previous studies have shown that mitochondrial petites of the yeast Saccharomyces cerevisiae appear to have some advantage over their wild type counterparts in terms of fermentative performance. In this thesis evidence is presented that inhibition of the respiratory chain by chemical or genetic means leads to an increase in ethanol formed per unit sugar and a decrease in biomass per unit sugar. The genetic studies involve a mutation in formation of subunit III of the cytochrome £ oxidase complex (pet!22) and a mutation in putative mitochondrial pyruvate transport (tpyl). The chemical study inv

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45

Murai, Toshiyuki. "Studies on genetic display of hydrolytic enzymes on yeast cell surface." Kyoto University, 1998. http://hdl.handle.net/2433/182354.

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46

Weisman, Ronit. "Genetic and molecular analysis of the wis2+ gene in fission yeast." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/13226.

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The <I>wis1<SUP>+</SUP></I>-<I>wis5<SUP>+</SUP></I> genes of the fission yeast <I>Schizosaccharomyces pombe</I> were isolated as multicopy suppressers of the cell cycle defect of the triple mutant <I>wee1-50 cdc25-22 win1-1</I>. The <I>wee-1</I> and <I>cdc25cdc25<SUP>+</SUP></I> gene products are negative and positive regulators, respectively, of p34<SUP>cdc2</SUP> protein kinase, the key regulator of entry into mitosis. The interaction of <I>win1-1</I> with mitotic control genes suggests that <I>win1<SUP>+</SUP></I> plays a role in the control over entry into mitosis. The work described in th

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47

Smith, Erin N. "Gene-environment interaction in yeast gene expression /." Thesis, Connect to this title online; UW restricted, 2008. http://hdl.handle.net/1773/5025.

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48

Webb, Penelope 1967. "Effects of yeast cell cycle gene expression in transgenic Nicotiana tabacum." Monash University, Dept. of Biological Sciences, 2001. http://arrow.monash.edu.au/hdl/1959.1/9084.

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49

Wang, Tsung-Tsan 1959. "Transformant system and gene expression of yeast Schwanniomyces occidentalis." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35955.

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Schwanniomyces occidentalis (Debaryomyces occidentalis ) is able to grow rapidly with high cell mass on cheap starch as a carbon source, produce strong amylolytic enzymes extracellularly and secrete large proteins without hyper-glycosylation and measurable extracellular proteases. Schw. occidentalis thus has a high potential as, a useful alternative to Saccharomyces cerevisiae in the production of heterologous proteins. However, the molecular study of Schw. occidentalis has been very limited due to the insufficient transformation system and lack of gene expression information.<br>A new transfo

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50

Butarbutar, Nunut. "Analysis of yeast codon usage patterns using the movable ORF collection /." Online version of thesis, 2007. http://hdl.handle.net/1850/5700.

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