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1

Shestak, Viktor, and Yulia Plutalovskaya. "History of international legal regulation of genetics." OOO "Zhurnal "Voprosy Istorii" 2020, no. 12-2 (2020): 118–23. http://dx.doi.org/10.31166/voprosyistorii202012statyi38.

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The authors analyze in retrospect the impact of the film industry on society. Crimes «inspired» by cinematography are considered, as well as crimes that became the basis for popular films. Both recently released films and other products of the film industry are analyzed, as well as works that are internationally recognized as “masterpieces” of cinema. The authors study the impact of the film industry on ordinary people, especially young people and people with an unstable psyche, and also consider such a phenomenon as «copycat crimes» and identify its possible causes.
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2

Mousavi, Reza, Mahdi Eftekhari, and Mehdi Ghezelbash Haghighi. "A new approach to human microRNA target prediction using ensemble pruning and rotation forest." Journal of Bioinformatics and Computational Biology 13, no. 06 (2015): 1550017. http://dx.doi.org/10.1142/s0219720015500171.

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MicroRNAs (miRNAs) are small non-coding RNAs that have important functions in gene regulation. Since finding miRNA target experimentally is costly and needs spending much time, the use of machine learning methods is a growing research area for miRNA target prediction. In this paper, a new approach is proposed by using two popular ensemble strategies, i.e. Ensemble Pruning and Rotation Forest (EP-RTF), to predict human miRNA target. For EP, the approach utilizes Genetic Algorithm (GA). In other words, a subset of classifiers from the heterogeneous ensemble is first selected by GA. Next, the sel
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3

Wu, Liying, Youguo Hao, Chuanqiang Dai, et al. "Network Pharmacological Study of Achyranthis bidentatae Radix Effect on Bone Trauma." BioMed Research International 2021 (March 6, 2021): 1–14. http://dx.doi.org/10.1155/2021/5692039.

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Purpose. Bone trauma is a clinical condition that afflicts the majority of the world’s population. For the management of bone trauma, the underlying mechanisms of the drugs effective for bone healing are deemed necessary. Achyranthis bidentatae Radix (ABR) is a popular alternative medicine recommended in the treatment of bone trauma and injury, yet its mechanism of action persists to be vague. This study was conducted for the evaluation of the mode of action of ABR through network pharmacology in treating bone trauma. Methods. An extensive survey of published works led to the development of a
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Sarmah, Prabalee, GC Bora, and NK Chaurasia. "Assessment of genetic variability, heritability and genetic advance in brinjal (Solanum melongena L.)." Vegetable Science 44, no. 01 (2017): 142–44. http://dx.doi.org/10.61180/e65srg53.

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Brinjal (Solanum melongena L.), a crop of the Solanaceae family, is a popular and principal vegetable grown all over India. It is an important vegetable crop in poor’s man diet because of its good content of vitamin c, vitamins a, calcium, phosphorus, potassium and fatty acids and has about 97% of water content. In addition to its nutritional value, the health beneficial properties of brinjal made it a popular protective food in the charts of nutritionists for cardiovascular diseases and obesity. It is beneficial for regulation of blood sugar level due to its rich source of fibre and low solub
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Ginsberg, Karen. "FDA Approved? A Critique of the Artificial Insemination Industry in the United States." University of Michigan Journal of Law Reform, no. 30.4 (2025): 823. https://doi.org/10.36646/mjlr.30.4.fda.

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Artificial insemination by donor is becoming an increasingly popular means to achieving parenthood. While the majority of couples use artificial insemination to overcome fertility problems, many recipients use artificial insemination to avoid passing a genetic disease to their children. However, case studies reveal the inherent dangers of artificial insemination, namely the lack of proper screening methods to avoid passing genetic diseases to children born by artificial insemination. State-by-state regulation, federal guidelines, and private adjudication have all proven to be inadequate method
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6

Mulder, Rosa H., Jolien Rijlaarsdam, Maartje P. C. M. Luijk, et al. "Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation." Development and Psychopathology 29, no. 2 (2017): 491–503. http://dx.doi.org/10.1017/s095457941700013x.

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AbstractThe parent–child attachment relationship plays an important role in the development of the infant's stress regulation system. However, genetic and epigenetic factors such as FK506 binding protein 51 (FKBP5) genotype and DNA methylation have also been associated with hypothalamus–pituitary–adrenal axis functioning. In the current study, we examined how parent–child dyadic regulation works in concert with genetic and epigenetic aspects of stress regulation. We study the associations of attachment, extreme maternal insensitivity, FKBP5 single nucleotide polymorphism 1360780, and FKBP5 met
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7

Papazoglou, Georgios, and Pandelis Biskas. "Review and Comparison of Genetic Algorithm and Particle Swarm Optimization in the Optimal Power Flow Problem." Energies 16, no. 3 (2023): 1152. http://dx.doi.org/10.3390/en16031152.

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Metaheuristic optimization techniques have successfully been used to solve the Optimal Power Flow (OPF) problem, addressing the shortcomings of mathematical optimization techniques. Two of the most popular metaheuristics are the Genetic Algorithm (GA) and Particle Swarm Optimization (PSO). The literature surrounding GA and PSO OPF is vast and not adequately organized. This work filled this gap by reviewing the most prominent works and analyzing the different traits of GA OPF works along seven axes, and of PSO OPF along four axes. Subsequently, cross-comparison between GA and PSO OPF works was
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8

Meola, Carosena. "Infrared Thermography in the Architectural Field." Scientific World Journal 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/323948.

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Infrared thermography is becoming ever more popular in civil engineering/architecture mainly due to its noncontact character which includes two great advantages. On one side, it prevents the object, under inspection, from any alteration and this is worthwhile especially in the presence of precious works of art. On the other side, the personnel operate in a remote manner far away from any hazard and this complies well with safety at work regulations. What is more, it offers the possibility to quickly inspect large surfaces such as the entire facade of a building. This paper would be an overview
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ZHUANG, JIMMY J., and CRAIG P. HUNTER. "RNA interference in Caenorhabditis elegans: Uptake, mechanism, and regulation." Parasitology 139, no. 5 (2011): 560–73. http://dx.doi.org/10.1017/s0031182011001788.

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SUMMARYRNA interference (RNAi) is a powerful research tool that has enabled molecular insights into gene activity, pathway analysis, partial loss-of-function phenotypes, and large-scale genomic discovery of gene function. While RNAi works extremely well in the non-parasitic nematode C. elegans, it is also especially useful in organisms that lack facile genetic analysis. Extensive genetic analysis of the mechanisms, delivery and regulation of RNAi in C. elegans has provided mechanistic and phenomenological insights into why RNAi is so effective in this species. These insights are useful for the
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10

Shestibratov, K., I. Chubugina, and S. Zavriev. "Genetic Engineering Activity: Analysis of International and Russian Legislative Base." World Economy and International Relations, no. 12 (2014): 50–59. http://dx.doi.org/10.20542/0131-2227-2014-12-50-59.

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The development and ratification of the Cartagena Protocol on Biosafety to the Convention on Biological Diversity (hereinafter the Protocol) by 167 countries was a significant event in the sphere of international legal regulation of genetic engineering activity (GEA). The Protocol came into effect on September 11, 2003. The Protocol is the main starting point of the legislative base building in the GEA field for a number of countries, including all EU countries, China and Brazil. The US and Russia have not ratified the Cartagena Protocol. The main principle underlying the European concepts of
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11

Levushkin, A. N. "Contractual regulation of participation in shared-equity construction in the structure of development activities." Courier of Kutafin Moscow State Law University (MSAL)), no. 12 (February 18, 2023): 91–100. http://dx.doi.org/10.17803/2311-5998.2022.100.12.091-100.

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To date, construction has become one of the most popular and rapidly developing areas of the economy. The largest number of construction works within the framework of project activities is carried out in Moscow. Contractual regulation of participation in shared-equity construction in the structure of development activities can be firmly called not only relevant, but also a problematic issue worthy of deep scientific study and practical justification. The article defines the contractual regulation of participation in shared-equity construction in the structure of development activities based on
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ONISCHENKO, O. N. "GENETIC POLYMORPHISM OF THE GH, GDF9 GENES IN RUSSIAN MEAT MERINO SHEEP BREED." Sheep, goats, wool business, no. 2 (2023): 14–17. http://dx.doi.org/10.26897/2074-0840-2023-2-14-17.

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The article presents the results of PCR-RFLP analysis of the genotype distribution of the GH and GDF9 genes in sheep of the Russian meat merino breed (n = 100), bred in the conditions of the Stavropol Territory. The most popular are genetic markers that are interconnected with candidate genes, the protein products of which play a signifi cant role in the formation or regulation of physiological and biochemical processes. Using the PCR-RFLP methods, the specifi city of the allelic spectrum of the somatotropin and differential growth factor genes was established.
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Rakhmatulina, R. Sh. "DIGITAL DESIGN OBJECTS: FEATURES OF LEGAL REGULATION." Juridical Journal of Samara University 6, no. 4 (2020): 33–37. http://dx.doi.org/10.18287/2542-047x-2020-6-4-33-37.

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The article is devoted to digital design objects. The author analyzes the features of design objects, examines the influence of digital technologies on the creation of design objects. It is suggested to enter the sign of originality for design objects as for works of art. Digital technologies give an impulse and a different meaning to design objects. The designer combines various types of technologies using digital technology. Thus, the originality of the design product will consist of different components: user perception of the object, convenience, fashion, design of creative use and process
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14

Medland, Sarah E., and Peter K. Hatemi. "Political Science, Biometric Theory, and Twin Studies: A Methodological Introduction." Political Analysis 17, no. 2 (2009): 191–214. http://dx.doi.org/10.1093/pan/mpn016.

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As political scientists begin to incorporate biological influences as explanatory factors in political behavior, the need to present a methodological road map for utilizing biometric genetic theory and twin data is apparent. The classical twin design (CTD) remains the most popular design for initial examinations of the source of variance among social and political behaviors, and a vast majority of advanced variance components models as well as some molecular analyses are extensions of the CTD. Thus, it is appropriate to begin a series of works with the CTD and its most common variants. The CTD
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15

Ulitina, Olha. "The legal regulation of comics as copyright objects in Japan." Theory and Practice of Intellectual Property, no. 1-2 (March 27, 2025): 45–52. https://doi.org/10.33731/1-22023.277146.

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The article is devoted to the study of Japan's experience in legal regulation of the manga industry. Since the phenomenon of manga is of great importance to Japan, it is appropriate to study its experience in this field. Manga is an important cultural and economic phenomenon in Japan. The manga industry is developing and has a positive effect on economic processes in the country and on its image abroad. This became possible thanks to the effective legal regulation of the industry.Copyright law is at the heart of the commercial success of manga, as copyright mechanisms are used to effectively m
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16

Daev, Eugene V. "About stress, ... Or about Hans Selye’s two errors, conquered the world." Ecological genetics 17, no. 4 (2019): 103–11. http://dx.doi.org/10.17816/ecogen174103-111.

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Too broad understanding of the term stress, which Selye himself and his followers used in their popular science works, reduces its scientific value. Based on a brief analysis of examples of the ambiguity of the term stress, it is proposed to restore its research significance. For that, the concept of stress should be used more strictly and unequivocally and it would not be allowed to use a commonly broad understanding the term in scientific papers. In the frame of earlier Selyes stress definition, it suggests a more detailed structuring of the term based on levels of studying of living objects
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Royle, Camilla. "The Science and Politics of DNA." Monthly Review 68, no. 5 (2016): 56. http://dx.doi.org/10.14452/mr-068-05-2016-09_6.

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John Parrington, The Deeper Genome (Oxford: Oxford University Press, 2015), 272 pages, $19.95, paperback.John Parrington's book The Deeper Genome breaks new ground in establishing a materialist understanding of how the genome works. Most popular science books on genetics have dealt with the genetic code, focusing on the information contained in our genes and the physical or personality traits this information might "code for." Parrington instead turns his attention to the molecules that form our genomes, uncovering new research and assessing its implications for the way we think about genetics
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18

Carmona-Arroyo, Guadalupe, Marcela Quiroz-Castellanos, and Efrén Mezura-Montes. "Variable Decomposition for Large-Scale Constrained Optimization Problems Using a Grouping Genetic Algorithm." Mathematical and Computational Applications 27, no. 2 (2022): 23. http://dx.doi.org/10.3390/mca27020023.

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Several real optimization problems are very difficult, and their optimal solutions cannot be found with a traditional method. Moreover, for some of these problems, the large number of decision variables is a major contributing factor to their complexity; they are known as Large-Scale Optimization Problems, and various strategies have been proposed to deal with them. One of the most popular tools is called Cooperative Co-Evolution, which works through a decomposition of the decision variables into smaller subproblems or variables subgroups, which are optimized separately and cooperate to finall
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19

Tuzhilova-Ordanskaya, E. M., and E. V. Akhtyamova. "Issues of Civil Law Regulation Regarding the Protection of Civil Rights When Using Genetic Information." Вестник Пермского университета. Юридические науки, no. 52 (2021): 263–84. http://dx.doi.org/10.17072/1995-4190-2021-52-263-284.

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Introduction: the article deals with some basic legal issues that arise from the use of human genetic information. There exist some issues of defining the legal nature of such information, which we identify in the article. Current legal regulation is not able to take into account the peculiarities of genetic information and provide an effective protection against the misappropriation and improper use of genetic information when carrying out genetic diagnostics, working with biomaterials. At the moment, special public law and civil law regulation of the procedure for obtaining, accumulating, pr
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Wang, Zhang-Ying, An-Qing Shen, Yan-Xin Ge, et al. "Regulation of fruit quality formation in strawberry: from omics to biotechnology." PeerJ 13 (May 30, 2025): e19497. https://doi.org/10.7717/peerj.19497.

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Strawberry (Fragaria × ananassa Duch.), a popular fruit, is well known for its bright color, unique flavor, and high nutritional value. The quality of strawberries will greatly affect consumers’ choices, market share, and farmers’ profits. The formation of strawberry quality is a complex biological process involving the interaction of multiple genetic factors and environmental conditions. In recent years, there has been great progress on investigating strawberry quality formation and regulation in the world. In this review, we summarized the factors from internal to external that affect strawb
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21

Furs, V. V. "Semiotics of the fictional worlds: ideological (in)homogeneity of the transmedia franchises (by the example of fantasy stories and stories about superheroes)." Bulletin of Kazakh National Women's Teacher Training University, no. 2 (June 27, 2023): 71–83. http://dx.doi.org/10.52512/2306-5079-2023-94-2-71-83.

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The article presents the results of a semiotic analysis of fictional worlds in transmedia franchises. Fictional worlds of a number of popular fantasy narratives as well as stories about superheroes were chosen as the subject matter. In line with the goal stated in the introduction, this study focuses on how visual and narrative conventions encourage the circulation of certain connotative meanings between the various works of the transmedia franchise, maintaining the ideological homogeneity of its fictional world, as well as how a change in ideology can further develop the franchise and expand
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Mahmoodi, Masoomeh. "Social Criticism on Works of Contemporary Women Story Writers." Advances in Language and Literary Studies 8, no. 4 (2017): 50. http://dx.doi.org/10.7575/aiac.alls.v.8n.4p.50.

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Goldmann's genetic structuralism approach is one of the literary critique approaches and believes that the literary text are derived from the ideology governing the classes of society, and focuses on study of stories and their structures to know the social structures. A review of the changes made in the themes and subjects of the works of the Iranian story writers that most of them are from the middle class of society, indicates the growth of awareness and understanding of Iranian women about their identity and individuality and the achievement of conditions beyond what they are. Although in p
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MANGAL, MANISHA, ARPITA SRIVASTAVA, and B. S. TOMAR. "Genetic and molecular regulation of colour and pungency in Hot pepper (Capsicum spp): A review." Indian Journal of Agricultural Sciences 88, no. 3 (2018): 343–53. http://dx.doi.org/10.56093/ijas.v88i3.78389.

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Chilli (Capsicum spp) is an important horticultural crop both from its economic importance point of view and its nutritional value. It is an excellent source of natural colours and nutraceutical compounds. Chilli is a popular food ingredient in many parts of the world because of its two special attributes pungency and colour. It is pungent because of capsaicinoid alkaloids which get accumulated in the placenta of maturing fruits. The most abundant components of these compounds are capsaicin and dihydrocapsaicin. Capsaicinoids give a peppery flavour to meals and have various other interesting p
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Gadomski, Sebastian. "Scientific Narratives in Contemporary Egyptian Pocket Novel Series." Świat i Słowo 36, no. 1 (2021): 125–36. http://dx.doi.org/10.5604/01.3001.0014.7968.

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Popular literature occupies a significant part of the publishing market in Egypt and has had quite a large group of admirers for many decades. It is noteworthy that, in this sector, the series of Egyptian pocket stories published by the Modern Arab Association occupy a special position. It should be noted that the authors of the stories are heavily inspired by the latest scientific discoveries in many fields. In their works, medical facts, advanced technologies and genetic engineering not only set the background for the adventures of the characters, but are often the key elements of the plot a
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Durmaz, Asude Alpman, Emin Karaca, Urszula Demkow, Gokce Toruner, Jacqueline Schoumans, and Ozgur Cogulu. "Evolution of Genetic Techniques: Past, Present, and Beyond." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/461524.

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Genetics is the study of heredity, which means the study of genes and factors related to all aspects of genes. The scientific history of genetics began with the works of Gregor Mendel in the mid-19th century. Prior to Mendel, genetics was primarily theoretical whilst, after Mendel, the science of genetics was broadened to include experimental genetics. Developments in all fields of genetics and genetic technology in the first half of the 20th century provided a basis for the later developments. In the second half of the 20th century, the molecular background of genetics has become more underst
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Rakhmangulov, R. S. "Application of the CRISPR/Cas system for gene editing in ornamental crops." Plant Biotechnology and Breeding 5, no. 3 (2022): 33–41. http://dx.doi.org/10.30901/2658-6266-2022-3-o1.

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Ornamental plants are widespread and popular all over the world. Floriculture industry is of significant economic importance for some countries. Favorable prospects for the development of industrial floriculture were also noted for Russia. This can be facilitated by CRISPR/Cas, a breakthrough method of editing genes responsible for economically valuable traits of plants, which allows bypassing the limitations of the potential intraspecific variability of plants and solving the problem of obtaining non-transgenic modified plants. This article analyzes the current status of ornamental crop breed
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Allen, Garland E. "Eugenics and American social history, 1880–1950." Genome 31, no. 2 (1989): 885–89. http://dx.doi.org/10.1139/g89-156.

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Eugenics, the attempt to improve the human species socially through better breeding was a widespread and popular movement in the United States and Europe between 1910 and 1940; Eugenics was an attempt to use science (the newly discovered Mendelian laws of heredity) to solve social problems (crime, alcoholism, prostitution, rebelliousness), using trained experts. Eugenics gained much support from progressive reform thinkers, who sought to plan social development using expert knowledge in both the social and natural sciences. In eugenics, progressive reformers saw the opportunity to attack socia
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Sharma, Pabitra, Priya Bhusal, Pujan Adhikari, Rajiv Baral, and Indraman Tamrakar. "Parallel Operation of DC Converters in Isolated Pv-Wind DC Microgrid using Droop." KEC Journal of Science and Engineering 7, no. 1 (2023): 65–69. http://dx.doi.org/10.3126/kjse.v7i1.60539.

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With the increasing consumer loads operated by DC voltage, DC micro-grids are becoming popular in terms of reliability and efficiency. In DC micro-grids, a conventional droop control method has been used to share the load proportionally to their capacity; however it led to the reduction of reference bus voltage. This paper presents an adaptive droop controller designed to mitigate the trade-off between current sharing and voltage regulation of the DC micro-grid. To simulate and evaluate the suggested control approach, isolated dc-dc converters are used. The proposed scheme is simulated using M
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Sun, Qiwen, Zhaohang Cai, and Chunjuan Zhu. "A Novel Dynamical Regulation of mRNA Distribution by Cross-Talking Pathways." Mathematics 10, no. 9 (2022): 1515. http://dx.doi.org/10.3390/math10091515.

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In this paper, we use a similar approach to the one proposed by Chen and Jiao to calculate the mathematical formulas of the generating function V(z,t) and the mass function Pm(t) of a cross-talking pathways model in large parameter regions. Together with kinetic rates from yeast and mouse genes, our numerical examples reveal novel bimodal mRNA distributions for intermediate times, whereby the mode of distribution Pm(t) displays unimodality with the peak at m=0 for initial and long times, which has not been obtained in previous works. Such regulation of mRNA distribution exactly matches the tra
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Nasulea, Christian, Diana Florentina Nasulea, and Stelian Mihai Mic. "Innovation needs deregulation: the case of taxi and private hire companies." Proceedings of the International Conference on Business Excellence 12, no. 1 (2018): 651–60. http://dx.doi.org/10.2478/picbe-2018-0058.

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Abstract Every year seems to bring about new technologies that radically change the way we do things. New innovative business models come to life, that change the way the world works so much that a shift of mindset is required if we are to keep up. These days, the largest transport company in the world owns no cars, the largest accommodation provider owns no real estate, the largest retailer by value has no inventory of its own, and the most popular media owner creates no content. But what about the role of regulation in this brave new world? We take a look at the rivals, taxi companies and pr
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CHURKIN, ALEXANDER, MORIAH COHEN, YONAT SHEMER-AVNI, and DANNY BARASH. "BIOINFORMATIC ANALYSIS OF THE NEUTRALITY OF RNA SECONDARY STRUCTURE ELEMENTS ACROSS GENOTYPES REVEALS EVIDENCE FOR DIRECT EVOLUTION OF GENETIC ROBUSTNESS IN HCV." Journal of Bioinformatics and Computational Biology 08, no. 06 (2010): 1013–26. http://dx.doi.org/10.1142/s0219720010005087.

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The properties and origin of genetic robustness have recently been investigated in several works that examined microRNA stem-loop structures, and a variety of conclusions have been reached without agreement. Considering that this is a universal phenomenon that is not restricted to miRNAs, we recall the original work on this topic that began from looking at viral RNAs of several types. We provide a link to this work by examining the neutrality of HCV structural elements, performing a detailed bioinformatic analysis using RNA secondary structure predictions across genotypes. This study provides
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Cheong, Clara Y., and Thomas Lufkin. "Alternative Splicing in Self-Renewal of Embryonic Stem Cells." Stem Cells International 2011 (2011): 1–8. http://dx.doi.org/10.4061/2011/560261.

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Much of embryonic stem cell biology has focused on transcriptional expression and regulation of genes that could mediate its unique potential in self-renewal or pluripotency. In alignment with our present understanding on the genetic, protein, and epigenetic factors that may direct cell fate, we present a short overview of the often overlooked contribution of alternative splice variants to regulatory diversity. Progressing beyond the limitations of a fixed genomic sequence, alternative splicing offers an additional layer of complexity to produce protein variants that may differ in function and
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Gulyaeva, Elena E. "Principles of International Law in View of the Genetic Technology Development." Journal of Foreign Legislation and Comparative Law 20, no. 3 (2024): 68. http://dx.doi.org/10.61205/s199132220030579-2.

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Currently, genetic technologies are being developed, but legal regulation of this area, for example, in the field of human cloning, human research, assisted reproductive technologies, and work with biological samples for diagnostic purposes, is insufficient. The relevance of this research in the field of international law is confirmed by the increasing importance of general and special principles of international law, a number of which acquire new content. For example, the concepts of biosecurity and genomic sovereignty are being filled with the principle of sovereign equality of states, which
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Danelyan, Ruzanna, and Vasily Yakovlev-Chernyshev. "Biometric data: Specific Features of Legislative Regulation in Russia." Bulletin of the Kazan Law Institute of MIA Russia 15, no. 3 (2024): 26–33. http://dx.doi.org/10.37973/vestnikkui-2024-57-3.

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Introduction: the article investigates issues related to the legal regulation of biometric data. The significance of the study is due to the significance of data protection that characterises physiological and biological data involving constitutional rights. The aim of the study is to identify gaps in the legislation on biometric data and develop proposals for their improvement. Materials and Methods: the basis of the study was normative legal acts of Russian and foreign legislation, works of domestic and foreign researchers. The methodological basis of the study was general scientific methods
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35

Gonzalez-Prieto, Angel, Ignacio González-Prieto, Mario J. Duran, and Juan J. Aciego. "Dynamic Response in Multiphase Electric Drives: Control Performance and Influencing Factors." Machines 10, no. 10 (2022): 866. http://dx.doi.org/10.3390/machines10100866.

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Speed variable electric drives play a key role in the evolution of electrical mobility. The dynamic performance of these systems is a crucial feature for security purposes. For this reason, a large number of works are focused on identification of the most appropriate control technique to satisfy a transient scenario. In this regard, the dynamic abilities of linear and direct controllers were analysed for three-phase drives. Although some insights about their transient performance were obtained, there are yet some issues to be solved. For instance, speed response was typically omitted, some inf
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Ismoilova, F. R., and M. T. Rustamova. "Polymorphisms of cytokine genes in the mechanisms of development of inflammatory and ultrasonic gastric damage." Experimental and Clinical Gastroenterology, no. 12 (January 16, 2022): 134–38. http://dx.doi.org/10.31146/1682-8658-ecg-196-12-134-138.

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To date, sufficiently reliable data have been accumulated on the involvement of various cytokine genes, the products of which are directly involved in the regulation of the immune response in inflammatory processes of the gastric mucosa. However, among these works, studies devoted to the genetic mechanisms of the formation of inflammatory and ulcerative lesions of the stomach are few in number, and the data obtained are contradictory. Meanwhile, the identification of predisposing factors that can modulate the progression of the inflammatory process leading to the development of stomach ulcers
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Aliev, T. T. "Street-Art as a Work of Fine Art." Intellectual property law 2 (July 1, 2021): 28–32. http://dx.doi.org/10.18572/2072-4322-2021-2-28-32.

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Purpose. Street art has exploded: it pervades our back alleys, surrounds us at bus-stops, covers billboards, competes with advertising and generally serves as urban wallpaper in most cities. But what is street art? A far cry from mere graffiti, street art has gained some social acceptance, but it remains neither officially sanctioned like public art, nor institutionally condoned, like its more traditional artistic cousins in museums. Somewhere in between these two extremes, street art has emerged, occupying a metaphysically suspect grey area between illegal activity and bona fide art. This pap
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Frolova, T. S., V. A. Cherenko, O. I. Sinitsyna, and A. V. Kochetov. "Genetic aspects of potato resistance to phytophthorosis." Vavilov Journal of Genetics and Breeding 25, no. 2 (2021): 164–70. http://dx.doi.org/10.18699/vj21.020.

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Phytophthora infestans Mont. de Bary is the main oomycete pathogen of cultivated crops in the family Solanaceae, especially potato (Solanum tuberosum). Because potato is the fourth most cultivated crop worldwide, its annual losses from late blight are tremendous. Studies of the basic mechanisms of interaction between potato and the late blight pathogen not only expand the fundamental knowledge in this area, but also open up new possibilities for regulating these interactions in order to increase resistance to the pathogen. The interaction of potato and the late blight pathogen can be considere
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Zaitseva, Anastasiia. "Legal Protection of TV Programs and Shows as the Objects of Intellectual Property Rights." Culture and Arts in the Modern World, no. 20 (May 30, 2019): 77–87. https://doi.org/10.31866/2410-1915.20.2019.172399.

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The aim of the study. The article analyses the issues of legal protection of TV programs and shows as objects of intellectual property rights, and specifies the peculiarities of legal regulation of these objects and their place in the system of intellectual property rights. The rapid development of technology makes television and its products popular, which leads to the need to improve the legal protection of such an object of intellectual property rights as a television program (show). Methodology of the study. The main methodological principles in the research are general scientific and dedi
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Jensen, P. "Domestication, selection, behaviour and welfare of animals — genetic mechanisms for rapid responses." Animal Welfare 19, S1 (2010): 7–9. http://dx.doi.org/10.1017/s0962728600002189.

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AbstractIncreased production has been the major goal of animal breeding for many decades, and the correlated side-effects have grown to become a major issue in animal welfare. In this paper, the main genetic mechanisms in which such side-effects may occur are reviewed with examples from our own research in chickens. Pleiotropy, linkage and regulatory pathways are the most important means by which a number of traits may be affected simultaneously by the same selection pressure. Pleiotropy can be exemplified by the gene PMEL17 which causes a lack of black pigmentation in chickens and, simultaneo
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Xiong, Zujian, Xuejun Li, and Qi Yang. "PTTG has a Dual Role of Promotion-Inhibition in the Development of Pituitary Adenomas." Protein & Peptide Letters 26, no. 11 (2019): 800–818. http://dx.doi.org/10.2174/0929866526666190722145449.

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Pituitary Tumor Transforming Gene (PTTG) of human is known as a checkpoint gene in the middle and late stages of mitosis, and is also a proto-oncogene that promotes cell cycle progression. In the nucleus, PTTG works as securin in controlling the mid-term segregation of sister chromatids. Overexpression of PTTG, entering the nucleus with the help of PBF in pituitary adenomas, participates in the regulation of cell cycle, interferes with DNA repair, induces genetic instability, transactivates FGF-2 and VEGF and promotes angiogenesis and tumor invasion. Simultaneously, overexpression of PTTG indu
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Kozlov, K. N., M. P. Bankin, E. A. Semenova, and M. G. Samsonova. "Genomic prediction of plant traits by popular machine learning methods." Vavilov Journal of Genetics and Breeding 29, no. 3 (2025): 458–66. https://doi.org/10.18699/vjgb-25-49.

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A rapid growth of the available body of genomic data has made it possible to obtain extensive results in genomic prediction and identification of associations of SNPs with phenotypic traits. In many cases, to identify new relationships between phenotypes and genotypes, it is preferable to use machine learning, deep learning and artificial intelligence, especially explainable artificial intelligence, capable of recognizing complex patterns. 80 sources were manually selected; while there were no restrictions on the release date, the main attention was paid to the originality of the proposed appr
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Wang, Hongtao, Lifan Zhang, Peng Shen, Xuelian Liu, Rengui Zhao, and Junyi Zhu. "Transcriptomic Insight into Underground Floral Differentiation in Erythronium japonicum." BioMed Research International 2022 (January 18, 2022): 1–14. http://dx.doi.org/10.1155/2022/4447472.

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Erythronium japonicum Decne (Liliaceae) flowers in early spring after overwintering. Its sexual reproduction process includes an underground development process of floral organs, but the underlying molecular mechanisms are obscure. The present study is aimed at exploring the transcriptional changes and key genes involved at underground floral developmental stages, including flower primordium differentiation, perianth differentiation, stamen differentiation, and pistil differentiation in E. japonicum. Multistage high-quality transcriptomic data resulted in identifying putative candidate genes f
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Nadir, Khan1 Farzeen Shaba2 Abu Sehma3 Mohd Faizan4 Rumana Siddqui5 Dr. Mohd Abid6*. "A Comprehensive Review About Exploring the Functional Diversity, Structural Complexity, And Interconnectivity of RNA Molecules: Implications for Gene Regulation, Cellular Processes, And Therapeutic Innovations." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2171–80. https://doi.org/10.5281/zenodo.15398199.

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RNA (ribonucleic acid) is a versatile biomolecule that plays fundamental roles in gene expression, protein synthesis, and cellular regulation. Beyond its well-known functions in transcription and translation, RNA participates in various regulatory and structural processes essential for maintaining cellular homeostasis. This review explores the diversity of RNA molecules, including messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA), and non-coding RNAs such as small nuclear RNA (snRNA), microRNA (miRNA), small interfering RNA (siRNA), long non-coding RNA (lncRNA), circular RNA (cir
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Ulitina, Olha. "Features of copyright protection of some specific works of contemporary art." Theory and Practice of Intellectual Property, no. 5 (June 11, 2021): 36–42. http://dx.doi.org/10.33731/52020.233731.

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Ulitina O. Features of copyright protection of some specific works of contemporary art. The article is devoted to the legal protection issues of the atypical objects of copyright, which belong to modern arts. The place and role of such objects in the system of copyright objects are defined. Based on the study of doctrinal provisionson such atypical objects, their differences from traditional objects of copyright are determined. In article it is also indicated how the place of such objects in the system of contemporary art influences it.An analysis of the Ukrainian legislation and the foreign c
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Chen, Jiahao, Yihao Liu, Hongbo Zhao, et al. "CsHY5 Regulates Light-Induced Anthocyanin Accumulation in Camellia sinensis." International Journal of Molecular Sciences 26, no. 7 (2025): 3253. https://doi.org/10.3390/ijms26073253.

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Tea is one of the world’s major non-alcoholic beverages, popular for its health benefits and flavor. Purple-bud tea is particularly rich in anthocyanins, the concentration of which varies depending on the tea cultivar and cultivation conditions. While the genetic regulation of anthocyanin accumulation is well understood, the impact of environmental factors, such as light, on anthocyanin synthesis is less documented. In this study, we analyzed the anthocyanin content and the expression levels of anthocyanin biosynthesis genes (ABGs), CsAN1, and CsHY5, under different light intensities and durat
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Kuluev, Bulat, Kairat Uteulin, Gabit Bari, Elvina Baimukhametova, Khalit Musin, and Alexey Chemeris. "Molecular Genetic Research and Genetic Engineering of Taraxacum kok-saghyz L.E. Rodin." Plants 12, no. 8 (2023): 1621. http://dx.doi.org/10.3390/plants12081621.

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Natural rubber (NR) remains an indispensable raw material with unique properties that is used in the manufacture of a large number of products and the global demand for it is growing every year. The only industrially important source of NR is the tropical tree Hevea brasiliensis (Willd. ex A.Juss.) Müll.Arg., thus alternative sources of rubber are required. For the temperate zone, the most suitable source of high quality rubber is the Russian (Kazakh) dandelion Taraxacum kok-saghyz L.E. Rodin (TKS). An obstacle to the widespread industrial cultivation of TKS is its high heterozygosity, poor gr
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Kobylyansky, V. I. "The role of counterinsular hormones in the regulation of glucose homeostasis and the pathogenesis of type 2 diabetes mellitus in COPD." Problems of Endocrinology 67, no. 2 (2021): 93–101. http://dx.doi.org/10.14341/probl12566.

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The frequent combination of type 2 diabetes mellitus (T2DM) and chronic obstructive pulmonary disease (COPD) is an important socially significant and far from being studied problem. However, only a few works are devoted to it. To solve this problem, we analyzed the possible pathogenetic mechanisms from the standpoint of the impact on glucose homeostasis of the main hormones — insular and contrainsular.The analysis was carried out using various literature databases, including Index Medicus, Scopus, Pub Med, Embase, Cochrane and others for the period, with rare exceptions, for 2000–2020, of whic
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., Prabhavathi, Kiran Bamel, Anuradha Mal, and Roopali Pandey. "Role of osmoprotectants: transgenic approach for different stresses." Research Journal of Biotechnology 17, no. 7 (2022): 156–63. http://dx.doi.org/10.25303/1707rjbt1560163.

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Plants have an in-built mechanism to cope with various environmental stress conditions. One such approach is activation of genes which governs the stress conditions. Out of the many stress related genes, some genes code for osmolytes or osmoprotectants. These belong to a group of low molecular weight compounds which are non-toxic compounds and help in stabilizing cellular structures and enzymes during the stress situation. Since the family is quite big, so for a fair understanding, these are grouped into different categories. For a better understanding of osmoprotectant related gene expression
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Nelson, Scott A., and John A. Cooper. "A Novel Pathway that Coordinates Mitotic Exit with Spindle Position." Molecular Biology of the Cell 18, no. 9 (2007): 3440–50. http://dx.doi.org/10.1091/mbc.e07-03-0242.

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In budding yeast, the spindle position checkpoint (SPC) delays mitotic exit until the mitotic spindle moves into the neck between the mother and bud. This checkpoint works by inhibiting the mitotic exit network (MEN), a signaling cascade initiated and controlled by Tem1, a small GTPase. Tem1 is regulated by a putative guanine exchange factor, Lte1, but the function and regulation of Lte1 remains poorly understood. Here, we identify novel components of the checkpoint that operate upstream of Lte1. We present genetic evidence in agreement with existing biochemical evidence for the molecular mech
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