Academic literature on the topic 'Genipine'

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Journal articles on the topic "Genipine"

1

Bringmann, Gerhard, Andreas Hamm, Jürgen Kraus, Michael Ochse, Amal Noureldeen, and Dennis N. Jumbam. "Gardenamide A fromRothmannia urcelliformis (Rubiaceae) − Isolation, Absolute Stereostructure, and Biomimetic Synthesis from Genipine." European Journal of Organic Chemistry 2001, no. 10 (2001): 1983–87. http://dx.doi.org/10.1002/1099-0690(200105)2001:10<1983::aid-ejoc1983>3.0.co;2-g.

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2

Bringmann, Gerhard, Andreas Hamm, Juergen Kraus, Michael Ochse, Amal Noureldeen, and Dennis N. Jumbam. "ChemInform Abstract: Gardenamide A (I) from Rothmannia urcelliformis (Rubiaceae) - Isolation, Absolute Stereostructure, and Biomimetic Synthesis from Genipine (II)." ChemInform 33, no. 9 (2010): no. http://dx.doi.org/10.1002/chin.200209178.

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3

Yang, Yishun, Yue Ding, and Tong Zhang. "Biotransformation of Geniposide into Genipin by ImmobilizedTrichoderma reeseiand Conformational Study of Genipin." BioMed Research International 2018 (2018): 1–10. http://dx.doi.org/10.1155/2018/2079195.

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Trichoderma reeseiQM9414,Trichoderma viride3.316,Aspergillus nigerM85, andAspergillus nigerM92 were screened for hydrolyzing geniposide into genipin.T. reeseiwas selected according to theβ-glucosidase activity of the fermentation broths using geniposide as a substrate.T. reeseiwas immobilized by embedding method using sodium alginate as the carrier. Geniposide was hydrolyzed by immobilizedT. reeseiat 28°C (200 rpm) for 34 h, and the yield of genipin was 89%. The product was purified and identified by UV, IR, EIMS, and1H-NMR. Since there were two sets of signals in1H-NMR spectra, a series of ex
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Sampaio, Greyce Yane Honorato, Ana C. B. M. Fook, Thiago Bizerra Fideles, M. E. R. R. M. Cavalcanti, and Marcus Vinícius Lia Fook. "Biodegradable Chitosan Scaffolds: Effect of Genipin Crosslinking." Materials Science Forum 805 (September 2014): 116–21. http://dx.doi.org/10.4028/www.scientific.net/msf.805.116.

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Currently researchers has pointed chitosan as one of the viable alternatives for application as scaffolds in tissue regeneration, mainly due to its availability, biocompatibility, biodegradability and ability to chemical modifications, among them, the crosslinking. With the growing number of investigations of crosslinking agents from natural sources and its applicability, this work focuses on the development and microstructural characterization of chitosan scaffolds and chitosan crosslinked with genipina using the technique of freeze drying. Solutions were prepared with chitosan concentration
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5

Dickson, Livia, Mathieu Tenon, Ljubica Svilar, et al. "Main Human Urinary Metabolites after Genipap (Genipa americana L.) Juice Intake." Nutrients 10, no. 9 (2018): 1155. http://dx.doi.org/10.3390/nu10091155.

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Genipap (Genipa americana L.) is a native fruit from Amazonia that contains bioactive compounds with a wide range of bioactivities. However, the response to genipap juice ingestion in the human exposome has never been studied. To identify biomarkers of genipap exposure, the untargeted metabolomics approach in human urine was applied. Urine samples from 16 healthy male volunteers, before and after drinking genipap juice, were analyzed by liquid chromatography–high-resolution mass spectrometry. XCMS package was used for data processing in the R environment and t-tests were applied on log-transfo
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Chen, Chungang, Fenxia Han, Yan Zhang, Jianfeng Lu, and Yuzhong Shi. "Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture ofAspergillus nigerby HPLC." Biomedical Chromatography 22, no. 7 (2008): 753–57. http://dx.doi.org/10.1002/bmc.993.

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7

Yunoki, Shunji, Yoshimi Ohyabu, and Hirosuke Hatayama. "Temperature-Responsive Gelation of Type I Collagen Solutions Involving Fibril Formation and Genipin Crosslinking as a Potential Injectable Hydrogel." International Journal of Biomaterials 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/620765.

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We investigated the temperature-responsive gelation of collagen/genipin solutions using pepsin-solubilized collagen (PSC) and acid-solubilized collagen (ASC) as substrates. Gelation occurred in the PSC/genipin solutions at genipin concentrations 0–2 mM under moderate change in temperature from 25 to 37°C. The PSC/genipin solutions exhibited fluidity at room temperature for at least 30 min, whereas the ASC/genipin solutions rapidly reached gel points. In specific cases PSC would be preferred over ASC as an injectable gel system. The temperature-responsive gelation of PSC/genipin solutions was d
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8

Zu, Yuangang, Xinyang Yu, Xiuhua Zhao, Weiguo Wang, and Kunlun Wang. "Nanocrystallization of the Pharmaceutically Active Agent Genipin by an Emulsion Solvent Evaporation Method." Journal of Nanomaterials 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/240950.

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To improve the water solubility and dissolution rate, genipin was nanocrystallized by an emulsion solvent evaporation method, followed by freeze-drying. The optimization condition of nanocrystallization process was carried out by single-factor experiment. The effects of five experimental parameters, such as concentration of surfactants the proportion of water to organic phase, homogenate speed and time, homogenization pressure and times, and the proportion of genipin to lyoprotectants on the mean particle size (MPS) of genipin nanoparticles, were investigated. Under the optimum conditions by s
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9

Ding, Yue, Jian-Wei Hou, Yong Zhang, et al. "Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/957030.

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Thein vivoandin vitrometabolism of genipin was systematically investigated in the present study. Urine, plasma, feces, and bile were collected from rats after oral administration of genipin at a dose of 50 mg/kg body weight. A rapid and sensitive method using ultraperformance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UPLC-Q/TOF MS) was developed for analysis of metabolic profile of genipin in rat biological samples (urine, plasma, feces, and bile). A total of ten metabolites were detected and identified by comparing their fra
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10

Wang, Ya, Tianming Zhao, You Deng, et al. "Genipin Ameliorates Carbon Tetrachloride-Induced Liver Injury in Mice via the Concomitant Inhibition of Inflammation and Induction of Autophagy." Oxidative Medicine and Cellular Longevity 2019 (December 11, 2019): 1–12. http://dx.doi.org/10.1155/2019/3729051.

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Genipin, as the most effective ingredient of various traditional medications, encompasses antioxidative, anti-inflammatory, and antibacterial capacities. More recently, it is suggested that genipin protects against septic liver damage by restoring autophagy. The purpose of the current study was to explore the protective effect of genipin against carbon tetrachloride- (CCl4-) induced acute liver injury (ALI) and its underlying molecular machinery. Our results indicated that treatment with genipin significantly reduced CCl4-induced hepatotoxicity by ameliorating histological liver changes, decre
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