Relevant bibliographies by topics / Genomic compartment

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Genomic compartment'

Author: Grafiati
Published: 9 October 2021
Last updated: 18 July 2025

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Journal articles on the topic "Genomic compartment"

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Szczepińska, Teresa, Ayatullah Faruk Mollah, and Dariusz Plewczynski. "Genomic Marks Associated with Chromatin Compartments in the CTCF, RNAPII Loop and Genomic Windows." International Journal of Molecular Sciences 22, no. 21 (2021): 11591. http://dx.doi.org/10.3390/ijms222111591.

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The nature of genome organization into two basic structural compartments is as yet undiscovered. However, it has been indicated to be a mechanism of gene expression regulation. Using the classification approach, we ranked genomic marks that hint at compartmentalization. We considered a broad range of marks, including GC content, histone modifications, DNA binding proteins, open chromatin, transcription and genome regulatory segmentation in GM12878 cells. Genomic marks were defined over CTCF or RNAPII loops, which are basic elements of genome 3D structure, and over 100 kb genomic windows. Exper
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Bock, Jason B., Hugo T. Matern, Andrew A. Peden, and Richard H. Scheller. "A genomic perspective on membrane compartment organization." Nature 409, no. 6822 (2001): 839–41. http://dx.doi.org/10.1038/35057024.

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Bernardi, Giorgio. "The “Genomic Code”: DNA Pervasively Moulds Chromatin Structures Leaving no Room for “Junk”." Life 11, no. 4 (2021): 342. http://dx.doi.org/10.3390/life11040342.

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The chromatin of the human genome was analyzed at three DNA size levels. At the first, compartment level, two “gene spaces” were found many years ago: A GC-rich, gene-rich “genome core” and a GC-poor, gene-poor “genome desert”, the former corresponding to open chromatin centrally located in the interphase nucleus, the latter to closed chromatin located peripherally. This bimodality was later confirmed and extended by the discoveries (1) of LADs, the Lamina-Associated Domains, and InterLADs; (2) of two “spatial compartments”, A and B, identified on the basis of chromatin interactions; and (3) o
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Bian, Qian, Erika C. Anderson, Qiming Yang, and Barbara J. Meyer. "Histone H3K9 methylation promotes formation of genome compartments inCaenorhabditis elegansvia chromosome compaction and perinuclear anchoring." Proceedings of the National Academy of Sciences 117, no. 21 (2020): 11459–70. http://dx.doi.org/10.1073/pnas.2002068117.

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Genomic regions preferentially associate with regions of similar transcriptional activity, partitioning genomes into active and inactive compartments within the nucleus. Here we explore mechanisms controlling genome compartment organization inCaenorhabditis elegansand investigate roles for compartments in regulating gene expression. Distal arms ofC. eleganschromosomes, which are enriched for heterochromatic histone modifications H3K9me1/me2/me3, interact with each other bothin cisandin trans,while interacting less frequently with central regions, leading to genome compartmentalization. Arms ar
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López-Moyado, Isaac F., Ageliki Tsagaratou, Hiroshi Yuita, et al. "Paradoxical association of TET loss of function with genome-wide DNA hypomethylation." Proceedings of the National Academy of Sciences 116, no. 34 (2019): 16933–42. http://dx.doi.org/10.1073/pnas.1903059116.

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Cancer genomes are characterized by focal increases in DNA methylation, co-occurring with widespread hypomethylation. Here, we show that TET loss of function results in a similar genomic footprint. Both 5hmC in wild-type (WT) genomes and DNA hypermethylation in TET-deficient genomes are largely confined to the active euchromatic compartment, consistent with the known functions of TET proteins in DNA demethylation and the known distribution of 5hmC at transcribed genes and active enhancers. In contrast, an unexpected DNA hypomethylation noted in multiple TET-deficient genomes is primarily obser
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Hay, El Hamidi, and Romdhane Rekaya. "A multi-compartment model for genomic selection in multi-breed populations." Livestock Science 177 (July 2015): 1–7. http://dx.doi.org/10.1016/j.livsci.2015.03.027.

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Antony-Debré, Iléana, Vladimir T. Manchev, Nathalie Balayn, et al. "Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia." Blood 125, no. 6 (2015): 930–40. http://dx.doi.org/10.1182/blood-2014-06-585513.

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Key Points A half loss of RUNX1 activity leads to defects in primitive erythropoiesis, megakaryopoiesis, and proplatelet formation. An almost complete loss of RUNX1 activity leads to the amplification of the granulomonocytic compartment with increased genomic instability.
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Pulkina, A. A., M. V. Sergeeva, A. Krokhin, M. A. Stukova, and A. Egorov. "Evidence for the extracellular delivery of influenza NS1 protein." Microbiology Independent Research Journal (MIR Journal) 8, no. 1 (2021): 27–37. http://dx.doi.org/10.18527/2500-2236-2021-8-1-27-37.

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We constructed a reporter influenza A/Puerto Rico/8/1934 virus expressing truncated 124aa N-terminal NS1 protein fused to a luciferase reporter sequence (NanoLuc) without signal peptide. The reproduction activity of the vector correlated well with the luminescent activity in the lysates of infected cell cultures or mouse respiratory organ suspensions. Surprisingly, we found that luciferase enzymatic activity was present not only in the intracellular compartments but also in cell culture supernatants as well as in the sera or bronchiolar lavages of infected mice. This fact allowed us to formula
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Pulkina, Anastasia, Maria Sergeeva, Artem Krokhin, Marina Stukova, and Andrej Egorov. "Evidence for the extracellular delivery of influenza NS1 protein." MIR J 8, no. 1 (2021): 27–37. https://doi.org/10.18527/2500-2236-2021-8-1-27-37.

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   We constructed a reporter influenza A/Puerto Rico/8/1934 virus expressing truncated 124aa N-terminal NS1 protein fused to a luciferase reporter sequence (NanoLuc) without signal peptide. The reproduction activity of the vector correlated well with the luminescent activity in the lysates of infected cell cultures or mouse respiratory organ suspensions. Surprisingly, we found that luciferase enzymatic activity was present not only in the intracellular compartments but also in cell culture supernatants as well as in the sera or bronchiolar lavages of infected mice. This fact allowed
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Junaid, Alim, Baljinder Singh, and Sabhyata Bhatia. "Evolutionary insights into 3D genome organization and epigenetic landscape ofVigna mungo." Life Science Alliance 7, no. 1 (2023): e202302074. http://dx.doi.org/10.26508/lsa.202302074.

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Eukaryotic genomes show an intricate three-dimensional (3D) organization within the nucleus that regulates multiple biological processes including gene expression. Contrary to animals, understanding of 3D genome organization in plants remains at a nascent stage. Here, we investigate the evolution of 3D chromatin architecture in legumes. By using cutting-edge PacBio, Illumina, and Hi-C contact reads, we report a gap-free, chromosome-scale reference genome assembly ofVigna mungo, an important minor legume cultivated in Southeast Asia. We spatially resolvedV. mungochromosomes into euchromatic, tr
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Dissertations / Theses on the topic "Genomic compartment"

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Carron, Léopold. "Analyse à haute résolution de la structure spatiale des chromosomes eucaryotes Boost-HiC : Computational enhancement of long-range contacts in chromosomal contact maps Genome supranucleosomal organization and genetic susceptibility to disease." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS593.

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L’information génétique est portée par la molécule d’ADN, un polymère de nucléotides de très grande taille. Afin de mieux comprendre les mécanismes impactant le repliement de l’ADN, on peut exploiter une technique de génomique qui permet de quantifier les contacts entre régions distales du génome. Cette technique expérimentale appelée ’capture de conformation de chromosome’ (Hi-C) donne des informations quantitatives sur l’architecture et le repliement tridimensionnel des chromosomes dans le noyau. Largement utilisée chez l’Homme, la souris et la drosophile, cette technique a grandement évolué
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Adhinaveni, Ramesh. "Molecular analysis of different clinical presentations of chronic lymphocytic leukemia reveals novel molecular predictors and molecular heterogenety of different anatomical compartments." Doctoral thesis, Università del Piemonte Orientale, 2022. http://hdl.handle.net/11579/144065.

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Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) are different manifestation of the same lymphoproliferative disease. Our study aims at evaluating molecular markers that predispose to chemorefractoriness in CLL and to identify molecular landscape of the different anatomical compartments of SLL. Fludarabine, cyclophosphamide, and rituximab (FCR) is the most effective chemoimmunotherapy regimen for young and fit CLL patients devoid of TP53 disruption. A cohort of 287 patients receiving first-line FCR was analyzed by next generation sequencing (NGS). By univariate analysis,
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Gil, Jr José. "Characterizing the 3D organization of holocentric chromosomes in Bombyx mori." Electronic Thesis or Diss., Université Paris sciences et lettres, 2022. http://www.theses.fr/2022UPSLS084.

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L'organisation du génome dans le noyau cellulaire a été observée et décrite dans différents organismes depuis plus de 140 ans. La plupart des organismes où cela a été fait sont monocentriques, c’est-à-dire dont les chromosomes n’ont qu’un seul centromère. Il a été montré que les centromères contraignent fortement l'architecture des chromosomes en interphase, et j'ai contribué lors de ma thèse à l’écriture d’une revue décrivant ce phénomène (Muller et al., 2019). Cependant, à travers l'Arbre de la Vie eucaryote, on peut trouver plusieurs exemples d'organismes qui sont holocentriques, c’est-à-di
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Soler, Vila Paula 1989. "Multi-scale study of the genome architecture and its dynamical facets." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/668229.

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High-throughput Chromosome Conformation Capture (3C) techniques have provided a comprehensive overview of the genome architecture. Hi-C, a derivative of 3C, has become a reference technique to study the 3D chromatin structure and its relationship with the functional state of the cell. However, several aspects of the analysis and interpretation of Hi-C data remain a challenge and may hide a potential yet to be unveiled. In this thesis, we explore the structural landscape of multiple chromatin features. We developed an integrative approach combining in situ Hi-C data with nine additional omi
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Baudement, Marie-Odile. "Le HRS-Seq : une nouvelle méthode d'analyse à haut-débit des séquences génomiques associées aux compartiments nucléaires." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS103.

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Chez les organismes complexes, comme les mammifères, les séquences de régulation génomique, dispersées sur les chromosomes, peuvent interagir à l'intérieur de l'espace nucléaire pour effectuer des actions coordonnées de régulations géniques. La méthylation de l'ADN et les modifications post-traductionnelles des histones, en combinaison avec des séquences de régulation, des facteurs protéiques et des ARNs non codants, conduisent à une organisation supérieure de la chromatine spécifique du type cellulaire. Cependant, l'organisation et la dynamique de la chromatine in vivo à l'échelle supérieure
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Books on the topic "Genomic compartment"

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Vermeulen, Roel, Douglas A. Bell, Dean P. Jones, et al. Application of Biomarkers in Cancer Epidemiology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0006.

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Advancements in OMICs are now enabling investigators to explore comprehensively the biological consequences of exogenous and endogenous exposures by detecting molecular signatures of exposure, early signs of adverse biological effects, preclinical disease, and molecularly defined cancer subtypes. These new technologies have proven invaluable for assembling a comprehensive portrait of human exposure, health, and disease. This includes hypothesis-driven biomarkers, as well as platforms that can agnostically analyze entire biologic processes and “compartments,” including the measurement of small
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Book chapters on the topic "Genomic compartment"

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Eschenbrenner, Christoph J., Alice Feurtey, and Eva H. Stukenbrock. "Population Genomics of Fungal Plant Pathogens and the Analyses of Rapidly Evolving Genome Compartments." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0199-0_14.

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Zhang, Liguo, Yu Chen, and Andrew S. Belmont. "Measuring Cytological Proximity of Chromosomal Loci to Defined Nuclear Compartments with TSA-seq." In Spatial Genome Organization. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2497-5_8.

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Mary, Bakhanashvili. "The Role p53 Protein in DNA Repair." In P53 - A Guardian of the Genome and Beyond [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99051.

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The tumor suppressor p53 protein controls cell cycle and plays a vital role in preserving DNA integrity. p53 is activated by varied stress signals and the distribution of p53 between the different subcellular compartments depends on the cellular stress milieu. DNA repair pathways protect cells from damage that can lead to DNA breaks. The multi-functional p53 protein promotes DNA repair both directly and indirectly through multiple mechanisms; it accomplishes multi-compartmental functions by either numerous p53-controlled proteins or by its inherent biochemical activities. Accumulating evidence supports the contribution of p53 in the maintenance of the genomic integrity and in various steps of the DNA damage response, through its translocation into nucleus and mitochondria. p53 may also be utilized by viral polymerases in cytoplasm to maintain genomic integrity of viruses, thus expanding the role of p53 as a ‘guardian of the genome’. We summarize recent findings highlighting roles of p53 in DNA repair.
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"Interchromosome Domain Compartment." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_8598.

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Maynard Smith, John, and Eors Szathmary. "The evolution of templates." In The Major Transitions in Evolution. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780198502944.003.0008.

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In this chapter, we discuss the origin and early evolution of genetic replication. The argument is complex, so we start with a brief outline. Section 4.2 discusses the nature of replication. We draw a distinction between simple replicators, limited hereditary replicators and indefinite hereditary replicators. Continued evolution requires indefinite hereditary replicators: it seems that such replicators depend on some form of template reproduction. In section 4.3, we point out that there is an error threshold for the accuracy of replication: for a given total quantity of genetic information—for example, for a fixed number of bases—there is an upper limit on the error rate of replication. If the error rate rises above this limit, natural selection cannot maintain the information. This leads to what we have called Eigen's paradox. In the absence of specific enzymes, replication accuracy is low. Hence the total genome size must be small—almost certainly, less than 100 nucleotides. The genome is therefore too small to code for accurate replication machinery. There is a catch-22 situation: no enzymes without a large genome, and no large genome without enzymes. The next three sections discuss possible solutions to the paradox. Section 4.4 considers populations of replicating RNA molecules. We point out that the dynamics of replication are such as to lead to the stable coexistence of a diverse population, but we do not think that this constitutes a solution to the paradox. Section 4.5 discusses the hypercycle, a particular relationship between replicators that makes it possible for a greater total quantity of information to be maintained with a given accuracy of replication. We argue that the further evolution of hypercycles requires that they be enclosed within compartments, because otherwise they are sensitive to parasitic replicators. We also discuss, rather inconclusively, the possibility that, even in the absence of compartments, cooperation might evolve, by a processes analogous to kin selection, if the components of the hypercycle were confined to a surface. Finally, we discuss an alternative model, the stochastic corrector model. This also depends on the existence of compartments, but emphasizes the importance of stochastic effects arising if there are small numbers of each kind of molecule in a compartment. Essentially, small numbers serve to generate variation upon which selection can act.
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Bock, Ralph. "RNA editing in plant mitochondria and chloroplasts." In RNA Editing. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199638154.003.0003.

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Abstract In plants, genetic information is distributed among three cellular compartments: the nucleus, mitochondria and plastids. Each of these compartments carries its own genome and, consequently, expresses heritable traits. Plastids and mitochondria do not obey Mendelian rules and are often transmitted uniparentally to the next generation, a phenomenon early recognized as being one of the characteristics of extranuclear inheritance (1).
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Bigger, B., RW Taylor, DM Turnbull,, and RN Lightowlers. "Gene therapy for mitochondrial DNA disorders." In Genetics of Mitochondrial Disease. Oxford University PressOxford, 2003. http://dx.doi.org/10.1093/oso/9780198508656.003.0017.

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Abstract Mutations of the mitochondrial genome (mtDNA) cause a variety of progressive clinical disorders for which there is no effective treatment. Consequently, novel therapeutic approaches are being considered. Mitochondrial genetics is complex, with single cells containing many hundreds or thousands of mtDNA molecules and in the disease state there are often populations of mutated and wild type mtDNA coexisting in the same cell or tissue. As the defective genome is expressed within the mitochondrial matrix surrounded by two membranes, any therapeutic molecule must reach this compartment.
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"IAP (intracisternal [within closed compartments] A particles)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_8155.

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Ulianov, Sergey V., Alexey A. Gavrilov, and Sergey V. Razin. "Nuclear Compartments, Genome Folding, and Enhancer-Promoter Communication." In International Review of Cell and Molecular Biology. Elsevier, 2015. http://dx.doi.org/10.1016/bs.ircmb.2014.11.004.

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Glover, J. R. "Mammalian HSP100." In Guidebook to Molecular Chaperones and Protein-Folding Catalysts. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198599494.003.00102.

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Abstract To date only a single representative of the HSP100 family has been cloned from a mammalian source. The gene (SKD3) was cloned as a suppressor of a potassium transport defect in yeast, suggesting a potential function for HSP100 proteins in solute transport. In addition to the gene from mouse, the human genome sequencing project has thus far contributed a number of partial cDNA sequences corresponding to HSPIOOs of at least two subfamilies. The prevalence of HSPIOOs in prokaryotes, in multiple subcellular compartments of eukaryotes suggests that many more mammalian HSPIOOs will be identified.
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Conference papers on the topic "Genomic compartment"

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Kua, Lindsay H., Fiona Y. Lee, Christine L. Eng, et al. "Abstract 3990: Tri-compartment (epithelial, immune, fibroblast) patient-derived models of the tumor microenvironment from an immuno-genomic profiled cohort of early stage colorectal cancers." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3990.

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Zambalde, Erika Pereira, Ana Carolina Rodrigues, Rubens Silveira Lima, Enilze Maria Souza Fonseca Ribeiro, and Jaqueline Carvalho Oliveira. "TLNC-UC.147, A NOVEL LONG RNA (lncRNA) FROM AN ULTRACONSERVED REGION AS POTENTIAL BIOMARKER IN LUMINAL A BREAST CANCER." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1052.

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Introduction: Long RNAs are non-coding RNAs with more than 200 nucleotides in length, with essential regulatory roles in several biological processes, including in breast cancer (BC). The human genome contains 481 ultraconserved regions, which are genomic stretches of over 200 base pairs conserved among humans, rats, and mice. Most of these regions are transcriptionally active (T-UCRs), and several are differentially expressed in tumors. Some T-UCRs have been functionally characterized, but few have been associated with BC. Objectives: In this study, we aimed to expand the knowledge of T-UCRs
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Kirchhof, Matthew, Christopher Jf Cameron, and Stefan C. Kremer. "End-to-end chromosomal compartment prediction from reference genomes." In 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2021. http://dx.doi.org/10.1109/bibm52615.2021.9669521.

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Yamshchikov, P. S., and I. V. Larionova. "REVEALING IMMUNE COMPARTMENTS USING DENOISING PROCEDURE OF SPATIAL TRANSCRIPTOMICS DATA FROM 10X GENOMICS VISIUM." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-44.

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Ovarian cancer has worse prognosis among gynecological malignancies. Tumor immune microenvironment significantly impact on disease prognosis. 10x Genomics Visium enables analysis of tumor immune microenvironment in a context of parenchymal-stromal relationships. Visium data biased due to “drop-out” effect. In current study we define optimal denoising strategy to reveal immune compartments in tissue section of ovarian cancer.
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Pasala, K. C., S. A. Putnikov, and V. N. Leonenko. "Calibrating deterministic compartmental models of infection dynamics using neural network and data sampling approaches." In 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine (CSGB). IEEE, 2022. http://dx.doi.org/10.1109/csgb56354.2022.9865428.

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"PARP1 activation directs RNA binding proteins to DNA damages to form PARG reversible compartments enriched in damaged DNA." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-359.

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Seth, Sahil, Chieh-Yuan Li, I.-Lin Ho, et al. "Abstract 1177: Clonal dissection of pancreatic tumors unmasks functional and genomic heterogeneous long-term self-renewing compartments at the origin of treatment resistance." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1177.

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Brouwer, A., P.-J. van Dam, A. Rutten, et al. "Abstract P1-06-01: Evaluation of subclonality in the CTC and DTC compartment of patients with metastatic breast cancer using low pass whole genome and AmpliSeq panel sequencing." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p1-06-01.

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Reports on the topic "Genomic compartment"

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Palmer, Guy, Varda Shkap, Wendy Brown, and Thea Molad. Control of bovine anaplasmosis: cytokine enhancement of vaccine efficacy. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7695879.bard.

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Anaplasmosis an arthropod-born disease of cattle caused by the rickettsia Anaplasma marginale and is an impediment to efficient production of healthy livestock in both Israel and the United States. Currently the only effective vaccines are derived from the blood of infected cattle. The risk of widespread transmission of both known and newly emergent pathogens has prevented licensure of live blood-based vaccines in the U.S. and is a major concern for their continued use in Israel. Consequently development of a safe, effective vaccine is a high priority. In this collaborative project we focused
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Paran, Ilan, and Allen Van Deynze. Regulation of pepper fruit color, chloroplasts development and their importance in fruit quality. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7598173.bard.

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Pepper exhibits large natural variation in chlorophyll content in the immature fruit. To dissect the genetic and molecular basis of this variation, we conducted QTL mapping for chlorophyll content in a cross between light and dark green-fruited parents, PI 152225 and 1154. Two major QTLs, pc1 and pc10, that control chlorophyll content by modulation of chloroplast compartment size in a fruit-specific manner were detected in chromosomes 1 and 10, respectively. The pepper homolog of GOLDEN2- LIKE transcription factor (CaGLK2) was found as underlying pc10, similar to its effect on tomato fruit chl
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Lapidot, Moshe, and Vitaly Citovsky. molecular mechanism for the Tomato yellow leaf curl virus resistance at the ty-5 locus. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604274.bard.

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Tomato yellow leaf curl virus (TYLCV) is a major pathogen of tomato that causes extensive crop loss worldwide, including the US and Israel. Genetic resistance in the host plant is considered highly effective in the defense against viral infection in the field. Thus, the best way to reduce yield losses due to TYLCV is by breeding tomatoes resistant or tolerant to the virus. To date, only six major TYLCV-resistance loci, termed Ty-1 to Ty-6, have been characterized and mapped to the tomato genome. Among tomato TYLCV-resistant lines containing these loci, we have identified a major recessive quan
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Cahaner, Avigdor, Sacit F. Bilgili, Orna Halevy, Roger J. Lien, and Kellye S. Joiner. effects of enhanced hypertrophy, reduced oxygen supply and heat load on breast meat yield and quality in broilers. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7699855.bard.

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Original objectivesThe objectives of this project were to evaluate the growth performance, meat yield and quality attributes of broiler strains widely differing in their genetic potential under normal temperature vs. warm temperature (short and long-term) conditions. Strain differences in breast muscle accretion rate, metabolic responses under heat load and, gross and histopathological changes in breast muscle under thermal load was also to be characterized. BackgroundTremendous genetic progress has been made in broiler chicken growth rate and meat yield since the 1950s. Higher growth rate is
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