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Journal articles on the topic 'Genomic research'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2025

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1

Stratakis, Constantine. "Applications of genomic medicine in endocrinology and post-genomic endocrine research." HORMONES 4, no. 1 (2005): 38–44. http://dx.doi.org/10.14310/horm.2002.11141.

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2

Hien, Le Thi Thu, Nguyen Tuong Van, Kim Thi Phuong Oanh, et al. "Genomics and big data: Research, development and applications." Vietnam Journal of Biotechnology 19, no. 3 (2021): 393–410. http://dx.doi.org/10.15625/1811-4989/16158.

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Recent years, genomics and big data analytics have been widely applied and have significant impacts in various important areas of social life worldwide. The development of the next-generation sequencing (NGS) technologies, such as whole-genome sequencing (WGS), whole-exome sequencing (WES), transcriptome, and/or targeted sequencing, has enabled quickly generating the genomes of interested living organisms. Around the world many nations have invested in and promoted the development of genomics and big data analytics. A number of well-established projects on sequencing of human, animal, plant, a

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Deck, John, Michelle Gaither, Rodney Ewing, et al. "The Genomic Observatories Metadatabase." Biodiversity Information Science and Standards 1 (August 22, 2017): e20508. https://doi.org/10.3897/tdwgproceedings.1.20508.

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The Genomic Observatories Metadatabase (GeOMe, http://www.geome-db.org/) is an open access repository for geographic and ecological metadata associated with biosamples and genetic data. It contributes to the informatics stack – Biocode Commons – of the Genomic Observatories Network (https://gigascience.biomedcentral.com/articles/10.1186/2047-217X-3-2). While public databases have served as vital repositories for nucleotide sequences, they do not accession all the metadata required for ecological or evolutionary analyses. These metadata are especially important for process oriented, time-series

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Lee, Hyunhwa, Jessica Gill, Taura Barr, Sijung Yun, and Hyungsuk Kim. "Primer in Genetics and Genomics, Article 2—Advancing Nursing Research With Genomic Approaches." Biological Research For Nursing 19, no. 2 (2017): 229–39. http://dx.doi.org/10.1177/1099800416689822.

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Purpose: Nurses investigate reasons for variable patient symptoms and responses to treatments to inform how best to improve outcomes. Genomics has the potential to guide nursing research exploring contributions to individual variability. This article is meant to serve as an introduction to the novel methods available through genomics for addressing this critical issue and includes a review of methodological considerations for selected genomic approaches. Approach: This review presents essential concepts in genetics and genomics that will allow readers to identify upcoming trends in genomics nu

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Bentley, Amy R., Shawneequa Callier, and Charles Rotimi. "The Emergence of Genomic Research in Africa and New Frameworks for Equity in Biomedical Research." Ethnicity & Disease 29, Suppl 1 (2019): 179–86. http://dx.doi.org/10.18865//ed.29.s1.179.

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Individuals with African ancestry have the greatest genomic diversity in the world, yet they have been underrepresented in genomic research. To advance our understanding of human biology and our ability to trace human history, we must include more samples from Africans in genomic research. Additionally, inclusion of more samples from participants of recent African descent is imperative to provide equitable health care as genomics is increasingly used for diagnosis, treatment, and to understand disease risk. The Human Heredity and Health in Africa initiative (H3Africa) seeks to expand the numb

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Bentley, Amy R., Shawneequa Callier, and Charles Rotimi. "The Emergence of Genomic Research in Africa and New Frameworks for Equity in Biomedical Research." Ethnicity & Disease 29, Suppl 1 (2019): 179–86. http://dx.doi.org/10.18865/ed.29.s1.179.

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Individuals with African ancestry have the greatest genomic diversity in the world, yet they have been underrepresented in genomic research. To advance our understanding of human biology and our ability to trace human history, we must include more samples from Africans in genomic research. Additionally, inclusion of more samples from participants of recent African descent is imperative to provide equitable health care as genomics is increasingly used for diagnosis, treatment, and to understand disease risk. The Human Heredity and Health in Africa initiative (H3Africa) seeks to expand the numb

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Howe, Kevin L., Bruno Contreras-Moreira, Nishadi De Silva, et al. "Ensembl Genomes 2020—enabling non-vertebrate genomic research." Nucleic Acids Research 48, no. D1 (2019): D689—D695. http://dx.doi.org/10.1093/nar/gkz890.

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Abstract Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of interfaces to genomic data across the tree of life, including reference genome sequence, gene models, transcriptional data, genetic variation and comparative analysis. Data may be accessed via our website, online tools platform and programmatic interfaces, with updates made four tim

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Ogunrin, Olubunmi, Funmilola Taiwo, and Lucy Frith. "Genomic Literacy and Awareness of Ethical Guidance for Genomic Research in Sub-Saharan Africa: How Prepared Are Biomedical Researchers?" Journal of Empirical Research on Human Research Ethics 14, no. 1 (2018): 78–87. http://dx.doi.org/10.1177/1556264618805194.

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Achieving the objectives of rolling out genomic research programs in sub-Saharan Africa depends on how prepared indigenous biomedical researchers are for this type of research. We explored the level of preparedness of biomedical researchers in a sub-Saharan African country using in-depth interviews to obtain data on their understanding of genomics and genomic research and assess their awareness of the scope of the country’s code of health research ethics. Thirty biomedical researchers were interviewed. Only eight were familiar with concepts of genomics, a form of “genomic health literacy.” The

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Šafář, J., J. Janda, J. Bartoš, et al. "Development of BAC resources for genomic research on wheat." Czech Journal of Genetics and Plant Breeding 41, Special Issue (2012): 202. http://dx.doi.org/10.17221/6173-cjgpb.

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10

Chadwick, Jennifer Q., Kenneth C. Copeland, Dannielle E. Branam, et al. "Genomic Research and American Indian Tribal Communities in Oklahoma: Learning From Past Research Misconduct and Building Future Trusting Partnerships." American Journal of Epidemiology 188, no. 7 (2019): 1206–12. http://dx.doi.org/10.1093/aje/kwz062.

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Abstract Research misconduct and consequential harms have been inflicted upon American Indian/Alaska Native communities for decades. To protect their people and culture and to retain oversight over research, many Native communities have established tribal health research and institutional review boards. The Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study showcases a successful, trusting research collaboration with tribal nations and academic investigators in Oklahoma. In 2006, the TODAY Study investigators proposed a modification of the study protocol to collect bi

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11

Garg, Kritika M., Vinita Lamba, Avirup Sanyal, Pilot Dovih, and Balaji Chattopadhyay. "Next Generation Sequencing Revolutionizes Organismal Biology Research in Bats." Journal of Molecular Evolution 91, no. 4 (2023): 391–404. https://doi.org/10.5281/zenodo.13476574.

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(Uploaded by Plazi for the Bat Literature Project) The advent of next generation sequencing technologies (NGS) has greatly accelerated our understanding of critical aspects of organismal biology from non-model organisms. Bats form a particularly interesting group in this regard, as genomic data have helped unearth a vast spectrum of idiosyncrasies in bat genomes associated with bat biology, physiology, and evolution. Bats are important bioindicators and are keystone species to many eco-systems. They often live in proximity to humans and are frequently associated with emerging infectious diseas

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Garg, Kritika M., Vinita Lamba, Avirup Sanyal, Pilot Dovih, and Balaji Chattopadhyay. "Next Generation Sequencing Revolutionizes Organismal Biology Research in Bats." Journal of Molecular Evolution 91, no. 4 (2023): 391–404. https://doi.org/10.5281/zenodo.13476574.

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(Uploaded by Plazi for the Bat Literature Project) The advent of next generation sequencing technologies (NGS) has greatly accelerated our understanding of critical aspects of organismal biology from non-model organisms. Bats form a particularly interesting group in this regard, as genomic data have helped unearth a vast spectrum of idiosyncrasies in bat genomes associated with bat biology, physiology, and evolution. Bats are important bioindicators and are keystone species to many eco-systems. They often live in proximity to humans and are frequently associated with emerging infectious diseas

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Garg, Kritika M., Vinita Lamba, Avirup Sanyal, Pilot Dovih, and Balaji Chattopadhyay. "Next Generation Sequencing Revolutionizes Organismal Biology Research in Bats." Journal of Molecular Evolution 91, no. 4 (2023): 391–404. https://doi.org/10.5281/zenodo.13476574.

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(Uploaded by Plazi for the Bat Literature Project) The advent of next generation sequencing technologies (NGS) has greatly accelerated our understanding of critical aspects of organismal biology from non-model organisms. Bats form a particularly interesting group in this regard, as genomic data have helped unearth a vast spectrum of idiosyncrasies in bat genomes associated with bat biology, physiology, and evolution. Bats are important bioindicators and are keystone species to many eco-systems. They often live in proximity to humans and are frequently associated with emerging infectious diseas

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Garg, Kritika M., Vinita Lamba, Avirup Sanyal, Pilot Dovih, and Balaji Chattopadhyay. "Next Generation Sequencing Revolutionizes Organismal Biology Research in Bats." Journal of Molecular Evolution 91, no. 4 (2023): 391–404. https://doi.org/10.5281/zenodo.13476574.

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Abstract:

(Uploaded by Plazi for the Bat Literature Project) The advent of next generation sequencing technologies (NGS) has greatly accelerated our understanding of critical aspects of organismal biology from non-model organisms. Bats form a particularly interesting group in this regard, as genomic data have helped unearth a vast spectrum of idiosyncrasies in bat genomes associated with bat biology, physiology, and evolution. Bats are important bioindicators and are keystone species to many eco-systems. They often live in proximity to humans and are frequently associated with emerging infectious diseas

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15

Garg, Kritika M., Vinita Lamba, Avirup Sanyal, Pilot Dovih, and Balaji Chattopadhyay. "Next Generation Sequencing Revolutionizes Organismal Biology Research in Bats." Journal of Molecular Evolution 91, no. 4 (2023): 391–404. https://doi.org/10.5281/zenodo.13476574.

Full text

Abstract:

(Uploaded by Plazi for the Bat Literature Project) The advent of next generation sequencing technologies (NGS) has greatly accelerated our understanding of critical aspects of organismal biology from non-model organisms. Bats form a particularly interesting group in this regard, as genomic data have helped unearth a vast spectrum of idiosyncrasies in bat genomes associated with bat biology, physiology, and evolution. Bats are important bioindicators and are keystone species to many eco-systems. They often live in proximity to humans and are frequently associated with emerging infectious diseas

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16

Baumgartel, Kelley, Jamie Zelazny, Theresa Timcheck, Chantel Snyder, Mandy Bell, and Yvette P. Conley. "Molecular Genomic Research Designs." Annual Review of Nursing Research 29, no. 1 (2011): 1–26. http://dx.doi.org/10.1891/0739-6686.29.1.

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Genetic and genomic research approaches have the capability to expand our understanding of the complex pathophysiology of disease susceptibility, susceptibility to complications related to disease, trajectory of recovery from acquired injuries and infections, patient response to interventions and therapeutics, as well as informing diagnoses and prognoses. Nurse scientists are actively involved in all of these fields of inquiry, and the goal of this chapter is to assist with incorporation of genetic and genomic trajectories into their research and facilitate the design and execution of these st

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17

Chandrasekaran, Adithan, Jayanthi Mathaiyan, and Sanish Davis. "Ethics of genomic research." Perspectives in Clinical Research 4, no. 1 (2013): 100. http://dx.doi.org/10.4103/2229-3485.106405.

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Pestrikova, A. A. "Risks of genomic research." Actual Problems of Russian Law, no. 8 (September 20, 2019): 55–61. http://dx.doi.org/10.17803/1994-1471.2019.105.8.055-061.

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The article considers the main achievements in the field of genetic engineering and biomedicine in the context of formation of the concept of legal regulation of relations in question. The article considers the issues of applying the human DNA editing technology considered by the Nuffield Council on Bioethics in July 2018. The author substantiates the necessity of determining the legal status of the embryo for its use in clinical trials of gene modifications. The paper considers the risks regarding the use of genetic engineering in relation to the person associated with the possibility of soci

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19

Gelbart, W. M. "Databases in Genomic Research." Science 282, no. 5389 (1998): 659–61. http://dx.doi.org/10.1126/science.282.5389.659.

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Poke, Fiona S., René E. Vaillancourt, Brad M. Potts, and James B. Reid. "Genomic Research in Eucalyptus." Genetica 125, no. 1 (2005): 79–101. http://dx.doi.org/10.1007/s10709-005-5082-4.

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21

Vavekanand, Raja. "Data Security and Privacy in Genomics Research: A Comparative Analysis to Protect Confidentiality." Studies in Medical and Health Sciences 1, no. 1 (2024): 23–31. http://dx.doi.org/10.48185/smhs.v1i1.1158.

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The quick progress of genomics examination has driven a surge in the creation of significantly fragile genomic data, making ensuring its security essential. This data contains sensitive information roughly an individual's prosperity, family history, and defencelessness to ailments. Unauthorized access or mishandling can lead to isolation, stigmatization, and mystery breaches. The potential threats to genomic data affirmation are multifaceted, checking the chance of re-identification and extended defense lessness to data breaches, hacking events, and unauthorized get to by harmful actors. To ad

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22

Trent, Jeffrey, John Carpten, Michael Reich, et al. "The Multiple Myeloma Research Consortium Genomics Initiative." Blood 110, no. 11 (2007): 2498. http://dx.doi.org/10.1182/blood.v110.11.2498.2498.

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Abstract The Multiple Myeloma Research Consortium (MMRC) Genomics Initiative is a three-year program to analyze tumor tissue from hundreds of multiple myeloma (MM) patients via gene expression profiling (GEP), comparative genomic hybridization (aCGH), and exon re-sequencing. In addition, RNAi knockdown of selected genes in MM tumor cell lines is being evaluated to identify potential new targets. All genomic data generated is scheduled for placement in an open-access Multiple Myeloma Genomics Portal pre-publication and in near real-time (www.broad.mit.edu/mmgp). Additionally, samples are also d

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Du, Xingjie, Yu Sun, Tong Fu, Tengyun Gao, and Tianliu Zhang. "Research Progress and Applications of Bovine Genome in the Tribe Bovini." Genes 15, no. 4 (2024): 509. http://dx.doi.org/10.3390/genes15040509.

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Various bovine species have been domesticated and bred for thousands of years, and they provide adequate animal-derived products, including meat, milk, and leather, to meet human requirements. Despite the review studies on economic traits in cattle, the genetic basis of traits has only been partially explained by phenotype and pedigree breeding methods, due to the complexity of genomic regulation during animal development and growth. With the advent of next-generation sequencing technology, genomics projects, such as the 1000 Bull Genomes Project, Functional Annotation of Animal Genomes projec

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Hiratsuka, Vanessa Y., Michael J. Hahn, R. Brian Woodbury, et al. "Alaska Native genomic research: perspectives from Alaska Native leaders, federal staff, and biomedical researchers." Genetics in Medicine 22, no. 12 (2020): 1935–43. http://dx.doi.org/10.1038/s41436-020-0926-y.

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AbstractMeaningful engagement of Alaska Native (AN) tribes and tribal health organizations is essential in the conduct of socially responsible and ethical research. As genomics becomes increasingly important to advancements in medicine, there is a risk that populations not meaningfully included in genomic research will not benefit from the outcomes of that research. AN people have historically been underrepresented in biomedical research; AN underrepresentation in genomics research is compounded by mistrust based on past abuses, concerns about privacy and data ownership, and cultural considera

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Smith, Timothy P. "226 Genomics in animal agriculture: current technologies and applications." Journal of Animal Science 97, Supplement_3 (2019): 55–56. http://dx.doi.org/10.1093/jas/skz258.113.

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Abstract The early impact of genomic research on animal agriculture was relatively modest, as it proved difficult to translate quantitative trait loci mapping to industrial application. Fortunately, developments in technology have facilitated the application of genomics to animal agriculture, which has led to more substantial impacts on many commercially produced animal species. A brief look back on the history of genomic research will be presented, followed by an overview of recent developments in genomic technologies. Examples of application of genomic research, focusing on beef cattle and c

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Benn, Emma, Yvette Hutson, Lewis Tomalin, et al. "209 The Clinical Research Education in Genome Science (CREiGS) short course: An innovative program for enhancing research capacity in genome science." Journal of Clinical and Translational Science 9, s1 (2025): 64–65. https://doi.org/10.1017/cts.2024.862.

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Objectives/Goals: The Clinical Research Education in Genome Science (CREiGS) program was developed to address the need for faculty and trainees conducting biomedical research to gain foundational training in genome science and accelerate the clinical adoption of genomic medicine. CREiGS, funded by NHGRI, offers comprehensive training in genomic analysis and statistical computing. Methods/Study Population: CREiGS targets a diverse pool of medical/doctoral students, postdocs, and faculty from academic institutions nationwide. The hybrid program included an 11-week online phase and a 3-day in-per

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Turbitt, Erin, and Barbara B. Biesecker. "A primer in genomics for social and behavioral investigators." Translational Behavioral Medicine 10, no. 2 (2019): 451–56. http://dx.doi.org/10.1093/tbm/ibz018.

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Abstract Genomics is being increasingly utilized in medical research and health care. Countless opportunities exist for social and behavioral scientists to answer novel and important research questions. Evidence that will be produced from such enquiries can help ensure appropriate use of genomic information and realize the potential of genomics to improve patient care and medical outcomes. Here, we provide an accessible overview of different types of genetic and genomic tests and the resulting information produced. There are important nuances that distinguish genetic from genomic tests and dif

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Coddington, Jonathan. "Global Genomic Resources for Biodiversity Research." Biodiversity Information Science and Standards 2 (July 19, 2018): e28440. http://dx.doi.org/10.3897/biss.2.28440.

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Genomic science is revolutionizing and accelerating biodiversity research. For collections-based institutions to continue to lead and support biodiversity research, they must adapt to this new reality. Simultaneously, “big data” is accumulating so rapidly that we have unprecedented capacity to plan strategically to use genomics to advance basic and applied science on multiple fronts. For example, seven “big data” sources (GBIF, ~1B records; BHL, ~3.6M records; NCBI, ~220M records; OToL, 1.9M records; BOLD, ~6.3M records, EOL, ~99K records, and GGBN, ~2M records) collectively offer more than 1.

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Coddington, Jonathan. "Global Genomic Resources for Biodiversity Research." Biodiversity Information Science and Standards 2 (July 19, 2018): e28440. https://doi.org/10.3897/biss.2.28440.

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Genomic science is revolutionizing and accelerating biodiversity research. For collections-based institutions to continue to lead and support biodiversity research, they must adapt to this new reality. Simultaneously, "big data" is accumulating so rapidly that we have unprecedented capacity to plan strategically to use genomics to advance basic and applied science on multiple fronts. For example, seven "big data" sources (GBIF, ~1B records; BHL, ~3.6M records; NCBI, ~220M records; OToL, 1.9M records; BOLD, ~6.3M records, EOL, ~99K records, and GGBN, ~2M records) collectively offer more than 1.

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Agha, Momal, and Faisal Khan. "Abstract 6310: Designing genomic test reports using a user-centered approach for clinicians in Pakistan." Cancer Research 82, no. 12_Supplement (2022): 6310. http://dx.doi.org/10.1158/1538-7445.am2022-6310.

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Abstract In the developed world, precision medicine and genomics are transforming traditional healthcare approaches. In spite of rapid technological progress being made in genomics, a 'genomic divide' is emerging between developed and developing countries. This is partly because of the limited genomic literacy of healthcare professionals and a scarcity of available genomics workforce that reportedly deters them from proposing genomic testing. We aim to help reduce this 'genomic divide' by proposing a genomic test report design for clinicians in Pakistan, that incorporates user-centered design

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Fitak, Robert R., Jennifer D. Antonides, Eric J. Baitchman, et al. "The Expectations and Challenges of Wildlife Disease Research in the Era of Genomics: Forecasting with a Horizon Scan-like Exercise." Journal of Heredity 110, no. 3 (2019): 261–74. http://dx.doi.org/10.1093/jhered/esz001.

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Abstract The outbreak and transmission of disease-causing pathogens are contributing to the unprecedented rate of biodiversity decline. Recent advances in genomics have coalesced into powerful tools to monitor, detect, and reconstruct the role of pathogens impacting wildlife populations. Wildlife researchers are thus uniquely positioned to merge ecological and evolutionary studies with genomic technologies to exploit unprecedented “Big Data” tools in disease research; however, many researchers lack the training and expertise required to use these computationally intensive methodologies. To add

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Guerrini, Christi J., and Jorge L. Contreras. "Credit for and Control of Research Outputs in Genomic Citizen Science." Annual Review of Genomics and Human Genetics 21, no. 1 (2020): 465–89. http://dx.doi.org/10.1146/annurev-genom-083117-021812.

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Citizen science encompasses activities with scientific objectives in which members of the public participate as more than passive research subjects from whom personal data or biospecimens are collected and analyzed by others. Citizen science is increasingly common in the biomedical sciences, including the fields of genetics and human genomics. Genomic citizen science initiatives are diverse and involve citizen scientists in collecting genetic data, solving genetic puzzles, and conducting experiments in community laboratories. At the same time that genomic citizen science is presenting new oppo

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Gordon, Elisa J., Zubairu Iliyasu, Elizabeth S. Rose, et al. "Building Capacity for the Ethical Conduct of Genetic and Genomic Research in Nigeria: The Vanderbilt-Nigeria Research Ethics Training Program." International Journal of Translational Medical Research and Public Health 9 (May 2, 2025): e007. https://doi.org/10.25259/ijtmrph_95_2024.

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Background and Objective The Vanderbilt-Nigeria Research Ethics Training Program (V-NET) is an innovative research ethics training program that aims to address the increasing demand for research in precision medicine in Africa by building capacity for the ethical design, conduct, and oversight of genetic and genomic research in Nigeria. Methods The program includes creation of a Master of Science (MSc) degree program in research ethics, training of 15 MSc students, and the integration of a genomics-focused ethics curriculum into a faculty enrichment program at Vanderbilt University Medical Cen

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Driscoll, Carolyn J., Debra Lyon, and Nancy L. McCain. "Integrating Genomics Into Biobehavioral Research." Biological Research For Nursing 13, no. 4 (2010): 340–45. http://dx.doi.org/10.1177/1099800410389603.

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Biobehavioral research is becoming more established in nursing. This research paradigm includes a focus on the interactions of biological and behavioral variables and their impact on health outcomes. Nurse researchers have incorporated genomics as a research focus. However, biobehavioral and genomic approaches have often been viewed as separate paradigms. This article provides research exemplars from the liver transplantation population to illustrate how genomics can be integrated into a biobehavioral model of nursing research. Examples of how this integrated approach may be utilized to addres

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Terry, May, Howard Anton, Michelle Casagni, Srikar Chamala, and James Lin Chen. "Exchanging genomics reports between pathology labs and medical centers using the Minimal Clinical Oncology Data Element (mCODE) FHIR implementation guide." Journal of Clinical Oncology 41, no. 16_suppl (2023): e13575-e13575. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e13575.

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e13575 Background: The automated transfer of discrete molecular data from pathology labs into the electronic health record (EHR) is rapidly becoming commonplace and is designed to facilitate clinical decision making. Simple genomic changes are represented in existing EHR data transfer standards, but current data standards lack clinical fields that correspond to treatment insights such as associated medications and potential clinical trials. To address this, the mCODE effort defines a consensus oncology data standard that facilitates lightweight transmission of data from patients with cancer. m

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Jowett, Stephanie, Elizabeth Dallaston, and Belinda Bennett. "Genomic Research and Data-Sharing." University of Queensland Law Journal 39, no. 2 (2020): 341–69. http://dx.doi.org/10.38127/uqlj.v39i2.5031.

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This article analyses the ethical and legal aspects of data-sharing and genomic research. It begins in Part II with an overview of the nature of genomic information, and whether it is exceptional when compared to other forms of health information. Part III considers the role of data-sharing in genomic research, with the importance of public trust in supporting genomic research considered in Part IV. The Australian regulatory framework for data-sharing in genomic research is considered in Parts V and VI, with reform options discussed in Part VII. The article concludes that advances in genomic r

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Jooma, Sonya, Michael J. Hahn, Lucia A. Hindorff, and Vence L. Bonham. "Defining and Achieving Health Equity in Genomic Medicine." Ethnicity & Disease 29, Suppl 1 (2019): 173–78. http://dx.doi.org/10.18865//ed.29.s1.173.

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The potential of genomics to improve health comes with the peril that the benefits will not be equitably available to all populations. Existing health disparities can be exacerbated if the implementation of genomic medicine does not intentionally focus on health equity. Defining what health equity means in the context of genomics and outlining how it can be achieved is important for the future of the field. Strategies to improve health equity include addressing underrepresentation of diverse populations in genomic research, investigating how genomic services can be deployed in diverse healt

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Jooma, Sonya, Michael J. Hahn, Lucia A. Hindorff, and Vence L. Bonham. "Defining and Achieving Health Equity in Genomic Medicine." Ethnicity & Disease 29, Suppl 1 (2019): 173–78. http://dx.doi.org/10.18865/ed.29.s1.173.

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The potential of genomics to improve health comes with the peril that the benefits will not be equitably available to all populations. Existing health disparities can be exacerbated if the implementation of genomic medicine does not intentionally focus on health equity. Defining what health equity means in the context of genomics and outlining how it can be achieved is important for the future of the field. Strategies to improve health equity include addressing underrepresentation of diverse populations in genomic research, investigating how genomic services can be deployed in diverse healt

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&NA;. "Genomic Research on Alcohol Dependence." Journal of Addictions Nursing 22, no. 4 (2011): 224–28. http://dx.doi.org/10.3109/10884602.2011.625157.

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Berrettini, W. "Setting Priorities for Genomic Research." Science 304, no. 5676 (2004): 1445c—1447c. http://dx.doi.org/10.1126/science.304.5676.1445c.

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Van Ness, Brian. "Genomic Research and Incidental Findings." Journal of Law, Medicine & Ethics 36, no. 2 (2008): 292–97. http://dx.doi.org/10.1111/j.1748-720x.2008.00272.x.

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Medical practice is poised to incorporate genomescale testing into treatment decisions. However, broad genome testing in laboratories may lead to discoveries not anticipated, yet highly significant to the health of the patient. Understanding the complexity of our genome and its relationship to our health is an overwhelming task. Currently, much of the effort to unravel this complexity is in the realm of research. However, researchers are often neither qualified nor prepared to deal with incidental findings of genetic abnormalities that influence health and disease. These incidental observation

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Gavaghan, Helen. "Europe boosts post-genomic research." Genome Biology 3 (2002): spotlight—20020327–01. http://dx.doi.org/10.1186/gb-spotlight-20020327-01.

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Walter, Ronald B., Zhenlin Ju, Al Martinez, Chris Amemiya, and Paul B. Samollow. "Genomic Resources for Xiphophorus Research." Zebrafish 3, no. 1 (2006): 11–22. http://dx.doi.org/10.1089/zeb.2006.3.11.

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Thomopoulos, Costas. "Genomic Research in Postmenopausal Hypertension." Journal of Clinical Hypertension 17, no. 7 (2015): 557. http://dx.doi.org/10.1111/jch.12538.

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Lowrance, W. W., and F. S. Collins. "ETHICS: Identifiability in Genomic Research." Science 317, no. 5838 (2007): 600–602. http://dx.doi.org/10.1126/science.1147699.

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Horowitz, Carol R., Lori A. Orlando, Anne M. Slavotinek, et al. "The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research." American Journal of Human Genetics 104, no. 6 (2019): 1088–96. http://dx.doi.org/10.1016/j.ajhg.2019.04.006.

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Gim, Jeong-An. "A Genomic Information Management System for Maintaining Healthy Genomic States and Application of Genomic Big Data in Clinical Research." International Journal of Molecular Sciences 23, no. 11 (2022): 5963. http://dx.doi.org/10.3390/ijms23115963.

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Improvements in next-generation sequencing (NGS) technology and computer systems have enabled personalized therapies based on genomic information. Recently, health management strategies using genomics and big data have been developed for application in medicine and public health science. In this review, I first discuss the development of a genomic information management system (GIMS) to maintain a highly detailed health record and detect diseases by collecting the genomic information of one individual over time. Maintaining a health record and detecting abnormal genomic states are important; t

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Ehman, Morgan, Nadine R. Caron, Laurie Montour, and Dean A. Regier. "Qualitative genomic research with Indigenous peoples: a scoping review of participatory practice." BMJ Global Health 9, no. 10 (2024): e015377. http://dx.doi.org/10.1136/bmjgh-2024-015377.

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IntroductionIndigenous peoples and perspectives are under-represented within genomic research. Qualitative methods can help redress this under-representation by informing the development of inclusive genomic resources aligned with Indigenous rights and interests. The difficult history of genomic research with Indigenous peoples requires that research be conducted responsibly and collaboratively. Research guidelines offer structuring principles, yet little guidance exists on how principles translate into practical, community-led methods. We identified the scope and nature of participatory pract

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Semyonovikh, Anastasiya E. "Epistemological issues of research of the subject and object of legal protection in genomic relations." RUDN Journal of Law 25, no. 4 (2021): 872–87. http://dx.doi.org/10.22363/2313-2337-2021-25-4-872-887.

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The relevance of the research topic is justified by the rapid technological development of genetics and genomics and introduction of genetic technologies and inventions in scientific and medical practice, which is not provided with a proper systematized legal protection in national and international legislation. The legislators problems are caused by the uniqueness and complexity of the genomic legal relationship. The subjects of knowledge in the framework of post-non-classical scientific rationality need to focus on the epistemological philosophical foundations of the knowledge of genomic leg

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Chan, Wing C., and Javeed Iqbal. "The Era of Genomic Research for Lymphoma: Looking Back and Forward." Hemato 3, no. 3 (2022): 485–507. http://dx.doi.org/10.3390/hemato3030034.

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Technological and informatics advances as well as the availability of well-annotated and reliable genomic data have ushered in the era of genomics research. We describe in this brief review how the genomics approach has impacted lymphoma research in the understanding of the pathogenesis and biology of lymphoma, in lymphoma diagnosis and in targeted therapy. Some exciting directions that could be explored in the future are also discussed.

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