Academic literature on the topic 'Genomics Big Data Engineering'

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Dissertations / Theses on the topic "Genomics Big Data Engineering"

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Goldstein, Theodore C. "Tools for extracting actionable medical knowledge from genomic big data." Thesis, University of California, Santa Cruz, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3589324.

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<p> Cancer is an ideal target for personal genomics-based medicine that uses high-throughput genome assays such as DNA sequencing, RNA sequencing, and expression analysis (collectively called <i>omics</i>); however, researchers and physicians are overwhelmed by the quantities of big data from these assays and cannot interpret this information accurately without specialized tools. To address this problem, I have created software methods and tools called <i>OCCAM</i> (OmiC&nbsp;data Cancer Analytic Model) and DIPSC (Differential Pathway Signature Correlation) for automatically extracting knowled
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Miller, Chase Allen. "Towards a Web-Based, Big Data, Genomics Ecosystem." Thesis, Boston College, 2014. http://hdl.handle.net/2345/bc-ir:104052.

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Thesis advisor: Gabor T. Marth<br>Rapid advances in genome sequencing enable a wide range of biological experiments on a scale that was until recently restricted to large genome centers. However, the analysis of the resulting vast genomic datasets is time-consuming, unintuitive and requires considerable computational expertise and costly infrastructure. Collectively, these factors effectively exclude many bench biologists from genome-scale analyses. Web-based visualization and analysis libraries, frameworks, and applications were developed to empower all biological researchers to easily, inter
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Hansen, Simon, and Erik Markow. "Big Data : Implementation av Big Data i offentlig verksamhet." Thesis, Högskolan i Halmstad, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-38756.

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Kämpe, Gabriella. "How Big Data Affects UserExperienceReducing cognitive load in big data applications." Thesis, Umeå universitet, Institutionen för datavetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-163995.

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We have entered the age of big data. Massive data sets are common in enterprises, government, and academia. Interpreting such scales of data is still hard for the human mind. This thesis investigates how proper design can decrease the cognitive load in data-heavy applications. It focuses on numeric data describing economic growth in retail organizations. It aims to answer the questions: What is important to keep in mind when designing an interface that holds large amounts of data? and How to decrease the cognitive load in complex user interfaces without reducing functionality?. It aims to answ
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Luo, Changqing. "Towards Secure Big Data Computing." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1529929603348119.

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Schobel, Seth Adam Micah. "The viral genomics revolution| Big data approaches to basic viral research, surveillance, and vaccine development." Thesis, University of Maryland, College Park, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10011480.

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<p> Since the decoding of the first RNA virus in 1976, the field of viral genomics has exploded, first through the use of Sanger sequencing technologies and later with the use next-generation sequencing approaches. With the development of these sequencing technologies, viral genomics has entered an era of big data. New challenges for analyzing these data are now apparent. Here, we describe novel methods to extend the current capabilities of viral comparative genomics. Through the use of antigenic distancing techniques, we have examined the relationship between the antigenic phenotype and the g
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Cheelangi, Madhusudan. "Result Distribution in Big Data Systems." Thesis, University of California, Irvine, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1539891.

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<p> We are building a Big Data Management System (BDMS) called <b>AsterixDB </b> at UCI. Since AsterixDB is designed to operate on large volumes of data, the results for its queries can be potentially very large, and AsterixDB is also designed to operate under high concurency workloads. As a result, we need a specialized mechanism to manage these large volumes of query results and deliver them to the clients. In this thesis, we present an architecture and an implementation of a new result distribution framework that is capable of handling large volumes of results under high concurency workload
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Laurila, M. (Mikko). "Big data in Finnish financial services." Bachelor's thesis, University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201711243156.

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This thesis aims to explore the concept of big data, and create understanding of big data maturity in the Finnish financial services industry. The research questions of this thesis are “What kind of big data solutions are being implemented in the Finnish financial services sector?” and “Which factors impede faster implementation of big data solutions in the Finnish financial services sector?”. Big data, being a concept usually linked with huge data sets and economies of scale, is an interesting topic for research in Finland, a market in which the size of data sets is somewhat limited by the si
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Flike, Felix, and Markus Gervard. "BIG DATA-ANALYS INOM FOTBOLLSORGANISATIONER En studie om big data-analys och värdeskapande." Thesis, Malmö universitet, Fakulteten för teknik och samhälle (TS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20117.

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Big data är ett relativt nytt begrepp men fenomenet har funnits länge. Det går att beskriva utifrån fem V:n; volume, veracity, variety, velocity och value. Analysen av Big Data har kommit att visa sig värdefull för organisationer i arbetet med beslutsfattande, generering av mätbara ekonomiska fördelar och förbättra verksamheten. Inom idrottsbranschen började detta på allvar användas i början av 2000-talet i baseballorganisationen Oakland Athletics. Man började värva spelare baserat på deras statistik istället för hur bra scouterna bedömde deras förmåga vilket gav stora framgångar. Detta ledde
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Nyström, Simon, and Joakim Lönnegren. "Processing data sources with big data frameworks." Thesis, KTH, Data- och elektroteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-188204.

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Big data is a concept that is expanding rapidly. As more and more data is generatedand garnered, there is an increasing need for efficient solutions that can be utilized to process all this data in attempts to gain value from it. The purpose of this thesis is to find an efficient way to quickly process a large number of relatively small files. More specifically, the purpose is to test two frameworks that can be used for processing big data. The frameworks that are tested against each other are Apache NiFi and Apache Storm. A method is devised in order to, firstly, construct a data flow and sec
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