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1

Chernyak, Yu I. "Association between HSPA1B, S100B, and TNF genes polymorphisms and risks of chronic mercury poisoning." Health Risk Analysis, no. 1 (March 2021): 126–32. http://dx.doi.org/10.21668/health.risk/2021.1.13.eng.

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We examined association between HSPA1B (+1267A/G, rs1061581), TNF-α (–308G/A, rs1800629), and S100B (C/T, rs9722) genes polymorphisms and chronic mercury poisoning (CMP). PCR-RFLP analysis was used to examine a cohort consisting of 128 workers who were chronically exposed to mercury vapor; workers were distributed into two groups. The group 1 was made up of workers with long working experience who didn’t have CMP (n = 46), the group 2 included patients with long-term CMP period (n = 82). In addition, we estimated frequencies of rs1061581genotypes in 298 practically healthy men from regional su
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2

Rahmiati, Tengku Mia, Yohanes Aris Purwanto, Slamet Budijanto, and Nurul Khumaida. "Sifat Fisikokimia Tepung dari 10 Genotipe Ubi Kayu (Manihot esculenta Crantz) Hasil Pemuliaan (Physicochemical Properties of Cassava Flour (Manihot esculenta Crantz) of 10 Breeding Genotipes)." Agritech 36, no. 4 (2017): 459. http://dx.doi.org/10.22146/agritech.16771.

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The objectives of this study were to characterize and evaluate the physicochemical properties of 10 cassava breeding genotypes developed by cassava crop improvement of (Institut Pertanian Bogor) IPB research group. The physicochemical characterization was performed by measuring water content, ash, protein, fat, carbohydrate, pasta (pasting properties), starch total, amylose content, and whiteness. The results showed that each genotype has different chemical content and gelatinization properties. The highest water content (11.48 ± 0.12 %) was found in genotype V4D0 (variant genotype Malang 4),
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3

Beckman, Joan, Karen L. Smith, Samuel T. Hester, Ofri Leitner, and Raj S. Kasthuri. "Effect of Genotype and Antifibrinolytic Therapy on the Severity of Epistaxis in Hereditary Hemorrhagic Telangiectasia." Blood 124, no. 21 (2014): 1515. http://dx.doi.org/10.1182/blood.v124.21.1515.1515.

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Abstract Background: Hereditary Hemorrhagic Telangiectasia (HHT, or Osler Weber Rendu syndrome) is an inherited multiorgan disorder characterized by the development of abnormal blood vessels, resulting in the formation of telangiectasias on mucocutaneous surfaces (skin, lips, nasal and buccal mucosa, gastrointestinal mucosa) and arteriovenous malformations (AVMs) in certain visceral organs (brain, lungs, spinal cord and liver). Over 90% of affected individuals develop epistaxis, often leading to complications, such as iron-deficiency anemia and the need for oral and parenteral iron supplementa
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4

Shukurova, F. N., D. A. Parpiboeva, and M. Sh Karimov. "Significance of genotyping in the diagnosis of arthritis associated with C-viral hepatitis." Experimental and Clinical Gastroenterology, no. 3 (May 22, 2021): 146–51. http://dx.doi.org/10.31146/1682-8658-ecg-187-3-146-151.

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To date, a number of studies have been conducted on the relationship of HCV genotypes with complications such as liver cirrhosis, hepatocellular carcinoma, but research on the correlation of the genotype with extrahepatic clinical manifestations associated with HCV, especially rheumatic manifestations, is insufficient. The purpose of the study is to analyze the most common genotypes of viral hepatitis C in the Republic of Uzbekistan and study their correlation with rheumatic manifestations of HCV. Methods: This study involved 88 patients with HCV infection who received inpatient and subsequent
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5

Tůmová, E., J. Vlčková, and D. Chodová. "Differences in oviposition and egg quality of various genotypes of laying hens." Czech Journal of Animal Science 62, No. 9 (2017): 377–83. http://dx.doi.org/10.17221/22/2017-cjas.

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The differences in egg production traits in six laying hen genotypes (brown-egg hens Bovans Brown, Bovans Sperwer, ISA Sussex; white-egg hen Dekalb White; laying hens with tinted shells Moravia Barred and Moravia BSL) and the interactions of genotype and oviposition on egg quality were evaluated. The genotype affected the laying rate (P ≤ 0.003), mean sequence length (P ≤ 0.001), and time of oviposition (P ≤ 0.001). The brown-egg genotypes laid eggs approximately 1 h earlier than the white-egg genotypes and approximately 2 h earlier than the tinted-egg genotypes. Egg shell strength was the low
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Blümel, Johannes, Anna Maria Eis-Hübinger, Albert Stühler, Claudia Bönsch, Matthias Gessner, and Johannes Löwer. "Characterization of Parvovirus B19 Genotype 2 in KU812Ep6 Cells." Journal of Virology 79, no. 22 (2005): 14197–206. http://dx.doi.org/10.1128/jvi.79.22.14197-14206.2005.

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ABSTRACT An infectious parvovirus B19 (B19V) genotype 2 variant was identified as a high-titer contaminant in a human plasma donation. Genome analysis revealed a 138-bp insertion within the p6 promoter. The inserted sequence was represented by an additional 30 bp from the end of the inverted terminal repeat adjacent to a 108-bp element found also, in inverted orientation, at the extreme right end of the unique sequence of the genome. However, despite the profound variations in the promoter region, the pattern of gene expression and DNA replication did not differ between genotype 1 and genotype
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7

Vanaja, Sivapriya Kailasan, Amber C. Springman, Thomas E. Besser, Thomas S. Whittam, and Shannon D. Manning. "Differential Expression of Virulence and Stress Fitness Genes between Escherichia coli O157:H7 Strains with Clinical or Bovine-Biased Genotypes." Applied and Environmental Microbiology 76, no. 1 (2009): 60–68. http://dx.doi.org/10.1128/aem.01666-09.

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ABSTRACT Escherichia coli O157:H7 strains can be classified into different genotypes based on the presence of specific Shiga toxin-encoding bacteriophage insertion sites. Certain O157:H7 genotypes predominate among human clinical cases (clinical genotypes), while others are more frequently found in bovines (bovine-biased genotypes). To determine whether inherent differences in gene expression explain the variation in infectivity of these genotypes, we compared the expression patterns of clinical genotype 1 strains with those of bovine-biased genotype 5 strains using microarrays. Important O157
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8

Rossiter, RC, GB Taylor, and L. Klein. "Environmental effects, in particular of rainfall, on the digestibility of dry mature subterranean clover." Australian Journal of Experimental Agriculture 34, no. 1 (1994): 25. http://dx.doi.org/10.1071/ea9940025.

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In vitro dry matter digestibility (DMD) was determined in dry mature subterranean clover (Trifolium subterraneum L.) from a field survey and from 2 field experiments. From the survey, the range in DMD between sites for individual cultivars was 9 percentage units (45-54%) through to 25 percentage units (35-60%). Differences in pattern of end-of-season rainfall over 3 years (experiment 2) resulted in changes in DMD ranging from 4 to 11 percentage units for the 4 genotypes examined. The 3 instances of midsummer rains were followed by decreases of 5-16 percentage units in DMD (experiments 1 and 2)
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9

Brewer, Marin Talbot, Omer Frenkel, and Michael G. Milgroom. "Linkage Disequilibrium and Spatial Aggregation of Genotypes in Sexually Reproducing Populations of Erysiphe necator." Phytopathology® 102, no. 10 (2012): 997–1005. http://dx.doi.org/10.1094/phyto-11-11-0321.

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Random mating and recombination in heterothallic ascomycetes should result in high genotypic diversity, 1:1 mating-type ratios, and random associations of alleles, or linkage equilibrium, at different loci. To test for random mating in populations of the grape powdery mildew fungus Erysiphe necator, we sampled isolates from vineyards of Vitis vinifera in Burdett, NY (NY09) and Winchester, VA (VA09) at the end of the epidemic in fall 2009. We also sampled isolates from the same Winchester, VA vineyard in spring 2010 at the onset of the next epidemic. Isolates were genotyped for mating type and
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10

Liang, Hsiao-Mei, Der-Yuh Lin, Yan-Der Hsuuw, et al. "Association of heat shock protein 70 gene polymorphisms with acute thermal tolerance, growth, and egg production traits of native chickens in Taiwan." Archives Animal Breeding 59, no. 2 (2016): 173–81. http://dx.doi.org/10.5194/aab-59-173-2016.

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Abstract. Heat stress is among the most challenging environmental conditions affecting commercial poultry. It severely affects growth and egg production, particularly in tropical and subtropical regions. This study aimed to examine physiological responses – including triiodothyronine (T3) levels, enzymatic activity of creatine kinase (CK) and lactate dehydrogenase (LDH), respiratory rates, and cloacal temperature – to acute heat stress associated with different genotypes of the HSP70 gene and to evaluate the association of these polymorphisms with growth and egg production. Genotyping was perf
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Faruque, Shakila, AKFH Bhuiyan, Md Yousuf Ali, and Ziaul Faruque Joy. "Breeding for the improvement of indigenous chickens of Bangladesh: performance of foundation stock." Asian Journal of Medical and Biological Research 3, no. 1 (2017): 80–87. http://dx.doi.org/10.3329/ajmbr.v3i1.32041.

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Selection is one of the vital tools for improving the indigenous chicken genetic resources. A total of 1585-day-old chicks comprising of 3 types of chicken namely Naked Neck (NN), Hilly (H) and Non-descript Deshi (ND) were hatched for this study to form foundation stock. Improvement target of egg weight was to increase by 1g and improvement target of egg production rate was to increase by 2 % per generation. In foundation stock, selection was practiced at 40-week of age, on the basis of an index comprising the parameters of age at first egg (ASM), body weight(BW), egg production(EP) and egg we
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12

Nosike, R. J., J. C. Ezike, C. N. Odukwe, O. F. Nwakpu, C. N. Okocha, and D. N. Onunkwo. "Naked-neck and frizzled feather fowls are high performance laying local chicken in Nigeria." Nigerian Journal of Animal Production 44, no. 5 (2020): 9–13. http://dx.doi.org/10.51791/njap.v44i5.1463.

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The study was conducted to investigate the effect of genotype on the laying performance of Nigerian local chicken. The experiment was carried out using 99 local chicken of the three genotypes, comprising of 90 hens and 9 cocks (33 frizzle feather, 33 naked-neck feather and 33 normal feathered). Eggs were collected from the different genotypes for 8 weeks. The laying performance traits were egg number, hen-housed (%) and hen-day (%) egg production. Data collected were subjected to ANOVA in a completely randomised design. The hen-day egg production showed significant differences (P<0.05) in a
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13

Steiner, Genevieve Z., Francesca M. Fernandez, Madilyn Coles, et al. "Interrogating the Relationship Between Schizotypy, the Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism, and Neuronal Oscillatory Activity." Cerebral Cortex 29, no. 7 (2018): 3048–58. http://dx.doi.org/10.1093/cercor/bhy171.

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Abstract The COMT Val158Met polymorphism affects the availability of synaptic dopamine in the prefrontal cortex and has been widely studied as a genetic risk factor for psychosis. Schizotypy is associated with an increased risk of psychosis, with some studies implicating similar neurobiological mechanisms to schizophrenia. The present study sought to interrogate the link between the COMT Val158Met polymorphism and schizotypy using electroencephalogram (EEG) to identify neurophysiological mechanisms underpinning psychosis risk. Neurotypical (N = 91) adults were genotyped for the COMT Val158Met
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14

Mansour, Hani A., Salwa El Sayed Mohamed, and David A. Lightfoot. "Molecular studies for drought tolerance in some Egyptian wheat genotypes under different irrigation systems." Open Agriculture 5, no. 1 (2020): 280–90. http://dx.doi.org/10.1515/opag-2020-0030.

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AbstractThis research work was carried out to evaluate drought stress for the differentiation of bread wheat (Triticum aestivum L.) genotypes in their ability to tolerate drought. An experiment was carried out on six genotypes (‘Sides 1’, ‘Shindwell 1’, ‘Gemmiza 9’, ‘Sakha 93’, ‘Saheel 1’ and ‘Masr 2’). A randomized complete block design with three replications along two separate tests under the drip and the sprinkler irrigation systems was used in this experiment. One of the irrigation treatments applied the normal amount of irrigation water and the other applied end-season drought stress con
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15

SKALLERUP, PER, STIG M. THAMSBORG, CLAUS B. JØRGENSEN, et al. "Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs." Parasitology 141, no. 6 (2014): 777–87. http://dx.doi.org/10.1017/s0031182013002175.

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SUMMARYTwo single nucleotide polymorphisms (SNP TXNIP and SNP ARNT), both on chromosome 4, have been reported to be associated with roundworm (Ascaris suum) burden in pigs. In the present study, we selected pigs with two SNP TXNIP genotypes (AA; n = 24 and AB; n = 24), trickle-infected them with A. suum from 8 weeks of age until necropsy 8 weeks later, and tested the hypothesis that pigs with the AA genotype would have higher levels of resistance than pigs of AB genotype. We used different indicators of resistance (worm burden, fecal egg counts (FEC), number of liver white spots and A. suum-sp
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16

Chuang, Wing Chia-Ming, and Jean-Pierre Allain. "Differential reactivity of putative genotype 2 hepatitis C virus F protein between chronic and recovered infections." Journal of General Virology 89, no. 8 (2008): 1890–900. http://dx.doi.org/10.1099/vir.0.83677-0.

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To date, all studies regarding hepatitis C virus (HCV) F protein have been based on expression in vitro/in vivo of recombinant protein or monoclonal antibodies derived from genotype 1a or 1b sequences, but not from other genotypes. The objective of this study was to prepare a putative genotype 2 recombinant F protein and evaluate its reactivity in plasma from individuals with chronic HCV infection or who had recovered from infection. One genotype 2 strain was selected for F protein (F-2) and core expression in bacterial culture. An ELISA was developed and applied to samples from patients with
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17

Dong, Hui, Feng-zhen Wang, Kun Shi, Xue-shan Zhang, and Dong-mei Lv. "Association of Cytochrome P450 2C9*3 and Angiotensin II Receptor 1 (1166A>C) Gene Polymorphisms With the Antihypertensive Effect of Irbesartan." American Journal of Hypertension 34, no. 1 (2021): 121. http://dx.doi.org/10.1093/ajh/hpaa134.

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Abstract Background To analyze whether the cytochrome P450 enzyme 2C9*3 (CYP2C9*3) and angiotensin II receptor 1 (AGTR1) (1166A>C) gene polymorphisms are associated with the risk of essential hypertension (EH) and the antihypertensive effect of irbesartan. Methods A total of 2,057 EH patients and 286 healthy controls were enrolled for genotyping in which 598 EH patients were given irbesartan 150 mg/day for 4 weeks. Blood pressure of all subjects were determined before and at the end of 4-week treatment. Results There was no significant difference in genotype frequencies of CYP2C9*3 and
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Azizian-Farsani, Fatemeh, Gholamreza Rafiei, and Mostafa Saadat. "Impact of Sodium Arsenite on Chromosomal Aberrations With Respect to Polymorphisms of Detoxification and DNA Repair Genes." International Journal of Toxicology 33, no. 6 (2014): 518–22. http://dx.doi.org/10.1177/1091581814557953.

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Arsenic compounds can increase production of reactive oxygen species. Reactive oxygen species can induce double-strand breaks in DNA, which is a cause of chromosome aberrations (CAs). This study was conducted to determine the association between arsenic exposure and polymorphisms of genes involved in detoxification (glutathione S-transferase T1 [ GSTT1], glutathione S-transferase M1 [ GSTM1], glutathione S-transferase O2 [ GSTO2], catalase [ CAT], and NAD(P)H quinone oxidoreductase1 [ NQO1]) as well as nonhomologous end joining DNA repair genes ( XRCC4, XRCC5, and XRCC6) with induction of chro
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SHWAB, E. KEATS, XING-QUAN ZHU, DEBASHREE MAJUMDAR, et al. "Geographical patterns of Toxoplasma gondii genetic diversity revealed by multilocus PCR-RFLP genotyping." Parasitology 141, no. 4 (2013): 453–61. http://dx.doi.org/10.1017/s0031182013001844.

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SUMMARYIn recent years, an extensive collection of Toxoplasma gondii samples have been typed using a set of 10 PCR-RFLP genetic markers. Here we summarize the data reported until the end of 2012. A total of 1457 samples were typed into 189 genotypes. Overall, only a few genotypes dominate in the northern hemisphere, which is in stark contrast to the southern hemisphere where hundreds of genotypes coexist with none being notably dominant. PCR-RFLP genotype #1 (Type II clonal), #2 (Type III), #3 (Type II variant) and #10 (Type I) are identified globally. Genotypes #2 and #3 dominate in Africa, g
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Alkan, Gülsüm, Faik Ekmel Tekintaş, Halil Güner Seferoğlu, and Engin Ertan. "Niğde Altunhisar Yöresi Bademlerinin Seleksiyonu." Turkish Journal of Agriculture - Food Science and Technology 2, no. 1 (2014): 51. http://dx.doi.org/10.24925/turjaf.v2i1.51-55.47.

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This study was to carried out to determine of promosing almond genotypes in Altunhisar county of Niğde province in 2013. 280 genotypes in terms of nut size, suture opening of the shell, shell thickness, softness of the shell, kernel color intensity, shriveling of kernel, kernel pubescence, kernel taste, percentage of double kernel, percentage of sound kernel, nut weight, shell thickness, nut length, nut width, nut thickness, nut shape, marking of outer shell, shell color, kernel weight, kernel length, kernel width, kernel thickness, kernel ratio, kernel size, percentages of twin kernels, width
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Rashid, MH, MA Alim, MK Rahman, et al. "Hepatitis E Vaccine: Present and Future." TAJ: Journal of Teachers Association 22, no. 2 (2009): 330–36. http://dx.doi.org/10.3329/taj.v22i2.37755.

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Viral hepatitis is a major public health problem in the world, and it can be caused by blood- and food-borne viruses. Blood-borne 'hepatitis agents are HBV, HCV and HDV, whereas HAV and HEV are food-borne hepatitis viruses. HEV infection is an important infectious agent in developing countries, but it is also an emerging disease in developed countries, which is likely due to travel or immigration from endemic areas. The main route of human HEV transmission is fecal-oral (fecally contaminated water), although other routes were also reported such as person-to-person transmission, blood products,
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Malespin, Miguel, Tamara Benyashvili, Susan L. Uprichard, Alan S. Perelson, Harel Dahari, and Scott J. Cotler. "Prevalence of end of treatment RNA-positive/sustained viral response in HCV patients treated with sofosbuvir combination therapies." Therapeutic Advances in Gastroenterology 10, no. 1 (2016): 68–73. http://dx.doi.org/10.1177/1756283x16672392.

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Background: Some chronic hepatitis C virus (HCV), genotype 1 infected patients treated with direct antiviral agents (DAAs) remain viremic at end of treatment (EOT+), yet go on to achieve sustained virological response 12 weeks after completion of therapy (SVR12). The incidence of EOT+/SVR in patients with genotype 1 and other genotypes, as well as whether such patients achieve SVR24 remain in question. The aims of this study were to evaluate the frequency and durability of EOT+/SVR12&24 and other response categories in HCV genotype 1, 2, or 3 infected patients treated with DAA in clinical
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Kaur, Rupinder, Seema Bedi, Gulshan Mahajan, Gurpreet Kaur, and Bhagirath Singh Chauhan. "Physiological and biochemical indicators for assessing nitrogen-use efficiency in rice (Oryza sativa) genotypes under dry direct seeding." Crop and Pasture Science 67, no. 11 (2016): 1158. http://dx.doi.org/10.1071/cp16204.

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To achieve high productivity of labour and water in rice cropping, farmers in South Asia have recently shown more interest in dry direct-seeded rice (DSR). An understanding of physiological and biochemical traits associated with high grain yield and efficiency of nitrogen (N) use is important to the development of genotypes for DSR. We investigated this issue with rice genotypes adapted to DSR in response to N rates. A 2-year study was conducted in a factorial randomised complete block design with eight genotypes and two N rates (75 and 150 kg N ha–1). Almost all of the physiological and bioch
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Howard, Tom E., Eugene Drigalenko, Matthew P. Johnson, et al. "Common SNPs within or near Three Immune Response Genes Implicated in the Risk of FVIII Immunogenicity in Hemophilia A Do Not Influence Steady-State Levels of Their Encoded mRNAs." Blood 120, no. 21 (2012): 3366. http://dx.doi.org/10.1182/blood.v120.21.3366.3366.

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Abstract Abstract 3366 Background/Aims: The hemophilia A (HA)-causing Factor (F)VIII gene (F8) mutation type is a well-established determinant of risk for the development of alloimmune inhibitors that neutralize replacement FVIII proteins in ∼20% of all HA patients. Studies have investigated variants of immune response genes to determine if they may account for the inter-individual variability in FVIII immunogenicity observed in patients with the same F8 abnormality, e.g., the intron-22 inversion. While some studies have found associations between inhibitor status and promoter polymorphisms in
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Su, Sui-Lung, Kuo-Cheng Lu, Yuh-Feng Lin, et al. "Gene polymorphisms of angiotensin-converting enzyme and angiotensin II Type 1 receptor among chronic kidney disease patients in a Chinese population." Journal of the Renin-Angiotensin-Aldosterone System 13, no. 1 (2011): 148–54. http://dx.doi.org/10.1177/1470320311430989.

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Chronic kidney disease (CKD) is highly prevalent in Taiwan and an increasing number of patients are affected, with a high risk of progression to end-stage renal disease and huge medical expenses. It has been predicted that the presence of hypertension increases with decreasing renal function due to a decrease in sodium excretion and activation of the renin–angiotensin system (RAS). The aim of this study was to investigate the influence of genetic variants of the RAS gene on CKD. We performed a case control association study and genotyped 135 CKD patients and 270 healthy controls among Han Chin
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von Ahsen, Nicolas, Michael Oellerich, and Ekkehard Schütz. "DNA Base Bulge vs Unmatched End Formation in Probe-based Diagnostic Insertion/Deletion Genotyping: Genotyping the UGT1A1 (TA)n Polymorphism by Real-Time Fluorescence PCR." Clinical Chemistry 46, no. 12 (2000): 1939–45. http://dx.doi.org/10.1093/clinchem/46.12.1939.

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Abstract Background: Gilbert syndrome is a clinically inconsequential entity of mild unconjugated hyperbilirubinemia caused by an A(TA)nTAA insertion polymorphism (UGT1A1*28) in the promoter region of the gene coding for the enzyme UDP-glucuronosyltransferase 1 (EC 2.4.1.17; UGT1A1). Present methods for genotyping this polymorphism are laborious. Methods: Hybridization probes were designed complementary to the wild type (TA)6 and to alleles with (TA)7 and (TA)8 repeats in the promoter region. Melting points were measured in samples representing all currently known alleles with (TA)5 to (TA)8 r
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Islam, MS, H. Khatun, MN Islam, S. Faruque, and MSK Sarker. "Study on the Productive and Reproductive Performances of BLRI-1 and BLRI-2 Ducks in Bangladesh." Agriculturists 12, no. 1 (2014): 10–14. http://dx.doi.org/10.3329/agric.v12i1.19485.

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A total of 887 ducklings of BLRI-1 duck genotype and 352 ducklings of BLRI-2 duck genotype were studied to measure productive and reproductive performances under intensive management. Data were recorded on body weight, egg production, egg weight, fertility, embryonic mortality, hatchability, feed intake, age at sexual maturity, body weight at maturity and egg weight at maturity. The fertility rate in BLRI-1duck was significantly (p<0.01) higher than that of BLRI-2 duck, while hatchability of BLRI-2 duck on fertile eggs were significantly (p<0.05) better compared to BLRI-1 duck. The embry
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Soo, R. A., S. C. Lee, S. S. Ng, et al. "Analysis of gemcitabine pathway genotypes in ethnic Asians and their relationship with outcome in non-small cell lung cancer (NSCLC) patients." Journal of Clinical Oncology 24, no. 18_suppl (2006): 2008. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.2008.

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2008 Background: Genotypic variation for drug metabolising enzymes, targets and transporters is associated with inter-patient and inter-ethnic variability in toxicity and efficacy. Gemcitabine is a nucleoside anti-metabolite used in a range of solid tumors. Aims: 1) to determine genotype distribution of genes involved in gemcitabine pharmacology pathway in ethnic groups; 2) to evaluate the association between genotypes and treatment related outcomes in patients with chemo-naive, advanced NSCLC receiving gemcitabine based chemotherapy on a prospective study. Methods: Candidate genes involved in
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Bokshi, Anowarul I., Daniel K. Y. Tan, Rebecca J. Thistlethwaite, Richard Trethowan, and Karolin Kunz. "Impact of elevated CO2 and heat stress on wheat pollen viability and grain production." Functional Plant Biology 48, no. 5 (2021): 503. http://dx.doi.org/10.1071/fp20187.

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Periods of high temperature and an expected increase in atmospheric CO2 concentration as a result of global climate change are major threats to wheat (Triticum aestivum L.) production. Developing heat-tolerant wheat cultivars demands improved understanding of the impacts of high temperature and elevated CO2 on plant growth and development. This research investigated the interactive effects of heat stress and CO2 concentration on pollen viability and its relationship to grain formation and yield of wheat in greenhouse conditions. Nineteen wheat genotypes and a current cultivar, Suntop, were hea
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Miller, Jeffrey S., Philip B. Hamm, and Dennis A. Johnson. "Characterization of the Phytophthora infestans Population in the Columbia Basin of Oregon and Washington from 1992 to 1995." Phytopathology® 87, no. 6 (1997): 656–60. http://dx.doi.org/10.1094/phyto.1997.87.6.656.

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Isolates of Phytophthora infestans collected from 1992 to 1995 from potato fields in the Columbia Basin of Oregon and Washington were analyzed for compatibility type, metalaxyl sensitivity, and glucose-6-phosphate isomerase (Gpi) genotype. In 1992, 30 of 31 isolates were of the US-1 multilocus genotype. A single metalaxyl-resistant isolate of the US-6 (A1 Gpi 86/100) genotype was found near the end of the growing season. In 1993, only 2 of the 59 isolates collected were A1 isolates with Gpi 86/100. Ten isolates were of the A2 compatibility type, seven with Gpi 100/111, two with Gpi 100/100, an
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Finn, Chad E., Andrew L. Thomas, Patrick L. Byers, and Sedat Serçe. "Evaluation of American (Sambucus canadensis) and European (S. nigra) Elderberry Genotypes Grown in Diverse Environments and Implications for Cultivar Development." HortScience 43, no. 5 (2008): 1385–91. http://dx.doi.org/10.21273/hortsci.43.5.1385.

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American (Sambucus canadensis L.) elderberry genotypes were evaluated at multiple locations, whereas European (S. nigra L.) elderberry genotypes were evaluated at a single location to assess genotypic differences and, for genotypes evaluated at multiple locations, to determine genotype × environment interactions (G × E). Seventeen S. canadensis genotypes were planted in replicated trials at Missouri State University (Mountain Grove, MO) and at the University of Missouri (Mt. Vernon, MO) or at the U.S. Department of Agriculture–Agricultural Research Service in Oregon (Corvallis). ‘Johns’, ‘Netz
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Farahat, G. S., B. Y. Mahmoud, E. M. El-Komy, and E. A. El-Full. "Alterations in plasma constituents, growth and egg production traits due to selection in three genotypes of Japanese quail." Journal of Agricultural Science 156, no. 1 (2018): 118–26. http://dx.doi.org/10.1017/s002185961700096x.

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AbstractThe present investigation was carried out to estimate the effects of genotype and sex on growth and laying performance and assess the variations in plasma constituents in the tested genotypes and their relations with productive traits after four generations of selection. Data of growth and laying performance on 1440 females and males of Japanese quail were taken from the three quail genotypes: maternal (MG), long shank length (LSG28) and control (CG) genotypes. Genotype significantly affected all studied growth productive traits, favouring selected genotypes. The LSG28surpassed MG in t
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33

Chiu, C. Y., A. L. Greninger, E. C. Chen, et al. "Cultivation and Serological Characterization of a Human Theiler's-Like Cardiovirus Associated with Diarrheal Disease." Journal of Virology 84, no. 9 (2010): 4407–14. http://dx.doi.org/10.1128/jvi.02536-09.

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ABSTRACT Cardioviruses (e.g., Theiler's murine encephalomyelitis virus [TMEV]) are members of the Picornaviridae family that cause myocarditis and encephalitis in rodents. Recently, several studies have identified human cardioviruses, including Saffold virus (SAFV) and a related virus named human TMEV-like cardiovirus (HTCV). At least eight cardiovirus genotypes are now recognized, with SAFV and most strains of HTCV belonging to genotypes 1 and 2, respectively; genotype 2 strains are the most common in the population. Although a genotype 3 cardiovirus has recently been cultured (SAFV-3), the g
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34

Gagliardi, Anna, Federica Carucci, Stefania Masci, Zina Flagella, Giuseppe Gatta, and Marcella Michela Giuliani. "Effects of Genotype, Growing Season and Nitrogen Level on Gluten Protein Assembly of Durum Wheat Grown under Mediterranean Conditions." Agronomy 10, no. 5 (2020): 755. http://dx.doi.org/10.3390/agronomy10050755.

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Water deficit and high temperatures are the main environmental factors which affect both wheat yield and technological quality in the Mediterranean climate. The aim of the study was to evaluate the variation in the gluten protein assembly of four durum wheat genotypes in relation to growing seasons and different nitrogen levels. The genotypes, Marco Aurelio, Quadrato, Pietrafitta and Redidenari, were grown under three nitrogen levels (36, 90 and 120 kg ha−1) during two growing seasons in Southern Italy. Significant lower yield and a higher protein concentration were observed in the year charac
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35

Kvanskaia, T. A., Z. N. Alekseeva, and O. V. Trapezov. "Molt of the American mink, depending on the genotype and nature of the behavior." Bulletin of NSAU (Novosibirsk State Agrarian University), no. 1 (March 26, 2021): 101–7. http://dx.doi.org/10.31677/2072-6724-2021-58-1-101-107.

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The object of research was the American mink, a predator, a semi-aquatic representative of the mustelidae family. The study was carried out on an adult population of males and females of the 22nd generation of different behavioral types and genotypes at the Experimental Fur Farm of the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences. The total number of studied animals was 547 ones of the Standard dark brown (+/+), Hedlund-white (h/h) and black crystal (CR/ +) genotypes. All animals were kept in the same conditions and received food edlibitum (lat.
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36

Faruque, Shakila, AKFH Bhuiyan, Md Yousuf Ali, and Ziaul Faruque Joy. "Breeding for the improvement of indigenous chickens of Bangladesh: evaluation of performance of first generation of indigenous chicken." Asian Journal of Medical and Biological Research 3, no. 1 (2017): 72–79. http://dx.doi.org/10.3329/ajmbr.v3i1.32039.

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Pure breeding is necessary for the conservation and improvement of indigenous chicken genetic resources. Present research is a part of the long-term selection program being undertaken to evaluate the performance and expected response to selection of first generation (G1) of three indigenous chicken genotypes under intensive management in Bangladesh. A total of 1439-day-old chicks comprising of 3 genotypes namely Naked Neck (NN), Hilly (H) and Non-descript Desi (ND) were hatched for this study. In first generation (G1), selection was practiced on body weight at 8 and 16 weeks of age, on the bas
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37

Yau, Alan Hoi Lun, and Eric M. Yoshida. "Hepatitis C Drugs: The End of the Pegylated Interferon Era and the Emergence of All-Oral, Interferon-Free Antiviral Regimens: A Concise Review." Canadian Journal of Gastroenterology and Hepatology 28, no. 8 (2014): 445–51. http://dx.doi.org/10.1155/2014/549624.

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Between 2001 and 2011, the standard of care for chronic hepatitis C virus (HCV) infection was a combination of pegylated interferon (PEGIFN) and ribavirin (RBV). In May 2011, boceprevir and telaprevir, two first-generation NS3/4A protease inhibitors, were approved in combination with PEG-IFN and RBV for 24 to 48 weeks in hepatitis C virus genotype 1 infections. In December 2013, simeprevir, a second-generation NS3/4A protease inhibitor, was approved for use with PEG-IFN and RBV for 12 weeks in genotype 1, while sofosbuvir, a NS5B nucleotide polymerase inhibitor, was approved for use with PEG-I
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Zhu, Jing, Tejendra Patel, Jordan A. Miller, et al. "Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients." International Journal of Molecular Sciences 21, no. 3 (2020): 858. http://dx.doi.org/10.3390/ijms21030858.

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Tacrolimus exhibits high inter-patient pharmacokinetics (PK) variability, as well as a narrow therapeutic index, and therefore requires therapeutic drug monitoring. Germline mutations in cytochrome P450 isoforms 4 and 5 genes (CYP3A4/5) and the ATP-binding cassette B1 gene (ABCB1) may contribute to interindividual tacrolimus PK variability, which may impact clinical outcomes among allogeneic hematopoietic stem cell transplantation (HSCT) patients. In this study, 252 adult patients who received tacrolimus for acute graft versus host disease (aGVHD) prophylaxis after allogeneic HSCT were genotyp
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39

Ulinnuha, Zulfa, Muhammad Achmad Chozin, and Edi Santosa. "The Growth, Fruit Set and Fruit Cracking Incidents of Tomato Under Shade." Journal of Tropical Crop Science 7, no. 02 (2020): 86–95. http://dx.doi.org/10.29244/jtcs.7.02.86-95.

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Six tomato genotypes were grown in the field under full sun at 50% reduced light intensity using shading net to evaluate growth, fruit set, and fruit cracking incident. The experiment was conducted during the rainy season in December 2016 to March 2017 in Cikarawang Experimental Station, Bogor, Indonesia. The genotypes tested were sensitive (“Tora” and F7005001-4-1-12-5), tolerant (F7003008-1-12-10-3 and F7003008-1-12-16-2), and shade-loving (SSH-3 and “Apel Belgia”). The results showed 50% shading delayed flowering and harvesting time in all genotypes. Genotype and shading treatments had an i
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Woo, Patrick C. Y., Susanna K. P. Lau, Cyril C. Y. Yip, et al. "Comparative Analysis of 22 Coronavirus HKU1 Genomes Reveals a Novel Genotype and Evidence of Natural Recombination in Coronavirus HKU1." Journal of Virology 80, no. 14 (2006): 7136–45. http://dx.doi.org/10.1128/jvi.00509-06.

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ABSTRACT We sequenced and compared the complete genomes of 22 strains of coronavirus HKU1 (CoV HKU1) obtained from nasopharyngeal aspirates of patients with respiratory tract infections over a 2-year period. Phylogenetic analysis of 24 putative proteins and polypeptides showed that the 22 CoV HKU1 strains fell into three clusters (genotype A, 13 strains; genotype B, 3 strains and genotype C, 6 strains). However, different phylogenetic relationships among the three clusters were observed in different regions of their genomes. From nsp4 to nsp6, the genotype A strains were clustered with the gen
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Otoo, E., K. Osei, J. Adomako, et al. "GGE Biplot Analysis of 12 Dioscorea rotundata Genotypes in Ghana." Journal of Agricultural Science 10, no. 1 (2017): 249. http://dx.doi.org/10.5539/jas.v10n1p249.

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To determine the effects of environment and genotypic differences on tuber yield and other related traits, 12 genotypes comprising 9 improved elite clones, two local landraces and 1 improved and released variety were evaluated for tuber yield, response to yam mosaic virus and leaf spot diseases at 16 growing environments. The multi-environment trials were conducted using randomized complete-block design with three blocks for four years in four representative agro-ecological zones (Atebubu, Kintampo, Ejura and Fumesua) in Ghana. The objective was to select high and stable yielding varieties for
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Khan, Mosin S., Abid Shoukat, Syed Mudassar, Zaffar Kawoosa, Altaf H. Shah, and Showkat Ali Zargar. "Impact of IL28B genetic variant's and viral genotype on treatment outcome of hepatitis C infected patients." Journal of Infection in Developing Countries 12, no. 09 (2018): 762–70. http://dx.doi.org/10.3855/jidc.10175.

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Introduction: Viral genotype and variation in host genes involved in the immune response may predict the treatment response in patients infected with HCV. The present study was designed to determine the distribution pattern of HCV and host genotypes in Chronic Hepatitis C (CHC) patients and their association with virological response and other risk factors.
 Methodology: Two hundred and fifty (n = 250) HCV positive patients were included in the study. HCV and Interleukin 28B (IL28B) genotyping was carried out by PCR-RFLP.
 Results: Viral genotype 3 was the predominant genotype seen i
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43

Ding, Yueyun, Chong Ding, Xudong Wu, et al. "Porcine LIF gene polymorphisms and their association with litter size traits in four pig breeds." Canadian Journal of Animal Science 100, no. 1 (2020): 85–92. http://dx.doi.org/10.1139/cjas-2018-0228.

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Leukemia inhibitory factor (LIF) is an important productivity-related gene in pigs. We found two polymorphisms — g.6646C>T and g.6988C>T — in exon 3 of LIF in pigs by using DNA sequencing and polymerase chain reaction-restriction fragment length polymorphism. Three genotypes were obtained and associated with litter size traits in Anqing Six-end-white (AQ), Wei (W), Wannan Black (WNB), and Large White (LW) pigs. At locus g.6646C>T, the g.6646C allele frequency variation was 0.6869 (AQ), 0.7473 (W), 1 (WNB), and 0.6852 (LW). In AQ pigs, sows with the TT genotype had higher total number
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Çöçen, Erdoğan, Hasan Pınar, Aydın Uzun, Mehmet Yaman, Ahmet Aslan, and Oktay Turgay Altun. "Türkiye Dut Genetik Kaynaklarında Bulunan Çekirdeksiz Beyaz Dutların Fenolojik, Pomolojik ve Teknolojik Özellikleri." Turkish Journal of Agriculture - Food Science and Technology 6, no. 10 (2018): 1317. http://dx.doi.org/10.24925/turjaf.v6i10.1317-1321.1775.

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This study carried out in 2015 and 2016 to determine phenological, pomological and some technological characteristics of 19 seedless mulberry genotypes of the Malatya Apricot Research Institute. Full-bloom periods of the genotypes varied between 27th of April (Poser 24-07) and 3rd of May (24 MRK 02); start of harvest dates varied between 15th of May (Poser 24-07) and 31st of May (Yediveren 24-08); end of harvest dates varied between 5th of July (Angut 009) and 30th of August (Yediveren 24-08). Fruiting durations varied between 50 days (Angut 009) and 95 days (Gemirgap Dutu 24-05). Of the pomol
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FRIMAT, LUC, CHRISTOPHE PHILIPPE, MARIE-NOËLLE MAGHAKIAN, et al. "Polymorphism of Angiotensin Converting Enzyme, Angiotensinogen, and Angiotensin II Type 1 Receptor Genes and End-Stage Renal Failure in IgA Nephropathy." Journal of the American Society of Nephrology 11, no. 11 (2000): 2062–67. http://dx.doi.org/10.1681/asn.v11112062.

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Abstract. The impact of renin-angiotensin system (RAS) gene polymorphism on the prognosis of IgA nephropathy (IgAN) is still debated. A longitudinal study of renal prognosis in patients with IgAN was conducted to search retrospectively for a genotype-phenotype association between RAS polymorphisms and end-stage renal failure (ESRF). A classification based on serum creatinine (Scr) and 24-h proteinuria (24-P) measured at the time of renal biopsy was used to estimate the risk of ESRF in IgAN: stage 1 (Scr ≤ 150 μmol/L and 24-P < 1 g), stage 2 (Scr > 150 μmol/L and 24-P < 1 g or Scr ≤ 15
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Dragovic, Tamara, Boris Ajdinovic, Rajko Hrvacevic, et al. "Angiotensin II type 1 receptor gene polymorphism could influence renoprotective response to losartan treatment in type 1 diabetic patients with high urinary albumin excretion rate." Vojnosanitetski pregled 67, no. 4 (2010): 273–78. http://dx.doi.org/10.2298/vsp1004273d.

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Background/Aim. Diabetic nephropathy (DN) is a clinical syndrome characterized by persistent albuminuria, increasing arterial blood pressure and progressive decline in glomerular filtration rate (GFR). When persistent albuminuria is established, antihypertensive treatment becomes most important factor in slowing the progression of diabetic glomerulopathy. The aim of this study was to examine if renoprotective response to a short-term losartan therapy depends on 1166 A/C gene polymorphism for its target receptor. Method. The study included 35 patients with diabetes mellitus type 1 and persisten
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Masante, Cyril, Kathleen Mahias, Sofia Lourenço, et al. "Seven nucleotide changes characteristic of the hepatitis C virus genotype 3 5′ untranslated region: correlation with reduced in vitro replication." Journal of General Virology 89, no. 1 (2008): 212–21. http://dx.doi.org/10.1099/vir.0.83067-0.

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Computer analysis of 158 hepatitis C virus (HCV) 5′ untranslated region (5′ UTR) sequences from the six genotypes showed that the 5′ UTR from genotype 3 displays seven specific non-contiguous nucleotide changes, at positions 8, 13, 14, 70, 97, 203 and 224. The purpose of this study was to investigate the impact of these changes on translation and replication activities. Indeed, these modifications could alter both the internal ribosome entry site (IRES) present in the 5′ UTR of the plus-strand RNA and the 3′ end of the minus strand involved in the initiation of plus-strand RNA synthesis. We fo
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48

Ahmed, S., A. Haque, H. Mahmud, and KM Khalequzzaman. "Egg deposition and weight loss of seeds by pulse beetle, Callosobruchus chinensis L. on different genotypes of pulses." Bangladesh Journal of Agricultural Research 44, no. 3 (2019): 513–24. http://dx.doi.org/10.3329/bjar.v44i3.43482.

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Lentil Lens culinarisMedik., mungbeanVignaradiata L. R. Wilczek, chickpea Cicer arietinum L. and blackgramVigna mungo L. Hepper of different genotypes were tested against pulse beetle, Callosobruchuschinensis L. in the laboratory of the Department of Entomology, Bangladesh Agricultural University (BAU), Mymensingh to evaluate the number of eggs deposition and percent weight loss of seeds. Maximum number of eggs (73.1) was oviposited on chickpea and minimum (19.5) was found on blackgram. The highest (19.9%) weight loss in seed was noted in chickpea and the lowest (7.6%) was recorded in blackgra
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49

Seguel, Alex, Pablo Cornejo, Ariel Ramos, Erik Von Baer, Jonathan Cumming, and Fernando Borie. "Phosphorus acquisition by three wheat cultivars contrasting in aluminium tolerance growing in an aluminium-rich volcanic soil." Crop and Pasture Science 68, no. 4 (2017): 305. http://dx.doi.org/10.1071/cp16224.

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Phosphorus (P) deficiency and aluminium (Al) phytotoxicity are major limitations for crop yield in acid soils. To ameliorate such limitations, agricultural management includes application of lime and P fertilisers, and the use of Al-tolerant plant genotypes. The mechanisms of Al tolerance and P efficiency may be closely related through strategies that decrease the toxicity of the Al3+ ion and increase P availability in soils. However, the effects of soils with high Al saturation on P acquisition by wheat have been little studied under field conditions. The aim of this work was to study Al–P in
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Cline, W. O., and M. K. Beute. "Effect of metam sodium, peanut genotype and inoculum density on incidence of Cylindrocladium black rot1." Peanut Science 13, no. 1 (1986): 41–45. http://dx.doi.org/10.3146/i0095-3679-13-1-13.

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Abstract Metam sodium was applied as an in-row preplant fumigant in field microplots planted with three peanut genotypes. Preplant inoculum densities of Cylindrocladium crotalariae were reduced 67% as compared to untreated controls. End-of-season inoculum densities were reduced an average of 32%. Across-plot soil sampling revealed no microsclerotia in treated row centers. Plantings of CBR-susceptible cultivar Florigiant with metam sodium treatments resulted in partial control of pod and root rot (caused by C. crotalariae), but high final inoculum densities. Metam sodium with moderately-resista
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