Academic literature on the topic 'Germ-cell sequestration'

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Journal articles on the topic "Germ-cell sequestration"

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Major, Andrew T., Cathryn A. Hogarth, Julia C. Young, Yasuyuki Kurihara, David A. Jans, and Kate L. Loveland. "Dynamic paraspeckle component localisation during spermatogenesis." Reproduction 158, no. 3 (2019): 267–80. http://dx.doi.org/10.1530/rep-19-0139.

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Expression profiles and subcellular localisations of core Drosophila behaviour/human splicing (DBHS) proteins (PSPC1, SFPQ and NONO) and NEAT1, a long noncoding RNA (lncRNA), are investigated in developing and adult mouse testes. Core DBHS proteins are markers for the distinct subnuclear domain termed paraspeckles, while a long NEAT1 isoform scaffold facilitates paraspeckle nucleation. Paraspeckles contain many proteins (>40) and are broadly involved in RNA metabolism, including transcriptional regulation by protein sequestration, nuclear retention of A-to-I edited RNA transcripts to regula
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Raju, Priyadharsini, Gunsmaa Nyamsuren, Manar Elkenani, et al. "Pelota mediates gonocyte maturation and maintenance of spermatogonial stem cells in mouse testes." REPRODUCTION 149, no. 3 (2015): 213–21. http://dx.doi.org/10.1530/rep-14-0391.

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Pelota (Pelo) is an evolutionarily conserved gene, and its deficiency in Drosophila affects both male and female fertility. In mice, genetic ablation of Pelo leads to embryonic lethality at the early implantation stage as a result of the impaired development of extra-embryonic endoderm (ExEn). To define the consequences of Pelo deletion on male germ cells, we temporally induced deletion of the gene at both embryonic and postnatal stages. Deletion of Pelo in adult mice resulted in a complete loss of whole-germ cell lineages after 45 days of deletion. The absence of newly emerging spermatogenic
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Boag, Peter R., Arzu Atalay, Stacey Robida, Valerie Reinke, and T. Keith Blackwell. "Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during Caenorhabditis elegans oogenesis." Journal of Cell Biology 182, no. 3 (2008): 543–57. http://dx.doi.org/10.1083/jcb.200801183.

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During oogenesis, numerous messenger RNAs (mRNAs) are maintained in a translationally silenced state. In eukaryotic cells, various translation inhibition and mRNA degradation mechanisms congregate in cytoplasmic processing bodies (P bodies). The P body protein Dhh1 inhibits translation and promotes decapping-mediated mRNA decay together with Pat1 in yeast, and has been implicated in mRNA storage in metazoan oocytes. Here, we have investigated in Caenorhabditis elegans whether Dhh1 and Pat1 generally function together, and how they influence mRNA sequestration during oogenesis. We show that in
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Lieberman, Bruce S., Warren D. Allmon, and Niles Eldredge. "Levels of selection: an analysis of the forces driving diversification in the turritellid gastropods." Paleontological Society Special Publications 6 (1992): 185. http://dx.doi.org/10.1017/s2475262200007450.

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This analysis examines the evolution of the greater diversity of non-planktonic species relative to planktonic species in the turritellid gastropods. Two mechanisms for generating diversity gradients in larval types have been proposed in the literature. The first, species selection or the effect hypothesis, focused on the population biology of larval types. The second proposed that factors in development were responsible. Turritellids have been cited as a classic example of species selection. In order to test the validity of these mechanisms for the evolution of the turritellids two phylogenet
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Lê, Phu-Quoc, Alina Ferster, Françoise Vertongen, et al. "National Clinical Data Base for Sickle Cell Disease In Belgium." Blood 116, no. 21 (2010): 2659. http://dx.doi.org/10.1182/blood.v116.21.2659.2659.

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Abstract Abstract 2659 Sickle cell disease (SCD) has polymorphic manifestations, it is not well known by many physicians, and patients have often a precarious status. So despite enormous improvements in the understanding of the pathogenesis of SCD, patient care remains difficult.The objectives of this work were to create a clinical data base in order to learn the characteristics of this population, to create a network between practitioners (general, emergency and specialist practitioners), to provide state-of-the art and guidelines, it could be a tool to disseminate information, for education
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Lennartz, M. R., A. F. Yuen, S. M. Masi, D. G. Russell, K. F. Buttle, and J. J. Smith. "Phospholipase A2 inhibition results in sequestration of plasma membrane into electronlucent vesicles during IgG-mediated phagocytosis." Journal of Cell Science 110, no. 17 (1997): 2041–52. http://dx.doi.org/10.1242/jcs.110.17.2041.

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Arachidonic acid is essential for antibody-mediated phagocytosis but its role in this process has not been defined. The phospholipase A2 inhibitor bromoenol lactone decreases arachidonic acid release and arrests phagocytosis; this effect is bypassed by the addition of arachidonic acid to bromoenol lactone-treated cells. In this morphological study, monocytes treated with bromoenol lactone accumulate electronlucent vesicles in the cytoplasm underlying bound targets. The vesicles are not contiguous with the plasma membrane as they are not labeled with cationized ferritin and are not connected to
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Kloc, Malgorzata, Yuri Shirato, Szczepan Bilinski, Leon W. Browder, and Jillian Johnston. "Differential subcellular sequestration of proapoptotic and antiapoptotic proteins and colocalization of Bcl-xL with the germ plasm, inXenopus laevis oocytes." genesis 45, no. 8 (2007): 523–31. http://dx.doi.org/10.1002/dvg.20322.

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Viny, Aaron D., Michael Clemente, Monika Jasek, Courtney Prince, and Jaroslaw P. Maciejewski. "Expression of MICA by Granulocytes in Neutropenia Due to Large Granular Lymphocyte Leukemia Points towards Cytotoxicity Exerted Via NKG2D on Clonal Cytotoxic T Cells." Blood 112, no. 11 (2008): 1262. http://dx.doi.org/10.1182/blood.v112.11.1262.1262.

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Abstract Large granular lymphocyte (LGL) leukemia is a semiautonomous proliferation of cytotoxic T cells (CTL) often accompanied by lineage-restricted immune cytopenias, including neutropenia and anemia. Clonal expansion of CD57+ CTL in LGL leukemia may constitute an extreme pole of a spectrum of immune-mediated responses that range from polyclonal such as in aplastic anemia, likely with multiple clones and target antigens, oligoclonal as in some immune-mediated cytopenias, to clonally-restricted LGL lymphoproliferations. Consequently, LGL leukemia may be a clonally exaggerated response to chr
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"The architecture of the life cycle in small organisms." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 332, no. 1262 (1991): 81–89. http://dx.doi.org/10.1098/rstb.1991.0035.

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The life cycle of eukaryotes has a dual nature, composed of a vegetative cycle of growth and reproduction, and a sexual cycle of fusion and reduction, linked by the spore. Large size is often favoured through interactions with other organisms, or as a means of exploiting locally or temporarily abundant resources, despite the metabolic penalty of size increase. Beyond a certain point, large organisms must be multicellular (or multinucleate) because of the requirement for more deoxyribonucleic acid (DNA) to service larger quantities of cytoplasm. Multicellularity evolves in some lineages but not
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Dissertations / Theses on the topic "Germ-cell sequestration"

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Balinski, Michael A. "Effects of non-standard alternative de novo mutations on evolution of drosophila melanogaster." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1593664676098449.

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