Relevant bibliographies by topics / Germinal centers

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  2. Dissertations / Theses
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  5. Conference papers

Academic literature on the topic 'Germinal centers'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 January 2023

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Journal articles on the topic "Germinal centers"

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Shlomchik, Mark J., and Florian Weisel. "Germinal centers." Immunological Reviews 247, no. 1 (2012): 5–10. http://dx.doi.org/10.1111/j.1600-065x.2012.01125.x.

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Victora, Gabriel D., and Michel C. Nussenzweig. "Germinal Centers." Annual Review of Immunology 30, no. 1 (2012): 429–57. http://dx.doi.org/10.1146/annurev-immunol-020711-075032.

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MacLennan, Ian C. M. "Germinal Centers." Annual Review of Immunology 12, no. 1 (1994): 117–39. http://dx.doi.org/10.1146/annurev.iy.12.040194.001001.

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Manser, Tim. "Textbook Germinal Centers?" Journal of Immunology 172, no. 6 (2004): 3369–75. http://dx.doi.org/10.4049/jimmunol.172.6.3369.

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Visan, Ioana. "Hypoxic germinal centers." Nature Immunology 17, no. 11 (2016): 1243. http://dx.doi.org/10.1038/ni.3594.

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Arakawa, Hiroshi, Kei-ichi Kuma, Masahiro Yasuda, Shuichi Furusawa, Shigeo Ekino, and Hideo Yamagishi. "Oligoclonal Development of B Cells Bearing Discrete Ig Chains in Chicken Single Germinal Centers." Journal of Immunology 160, no. 9 (1998): 4232–41. http://dx.doi.org/10.4049/jimmunol.160.9.4232.

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Abstract Chicken single germinal centers enable us to analyze the postbursal diversifications of B cells due to their easy isolation. Germinal center formation has peaked by day 7 of primary responses and begins to wane 14 days after immunization. To detail the kinetics of Ig mutation and selection, we analyzed Ig light chain sequences recovered from single germinal centers at 7 and 11 days postimmunization with an artificial Ag. Our observations show that multiple, Ag-activated B cells migrating into single germinal centers are diversified by gene conversion in the very early phase of the ger
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Toellner, Kai-Michael, William E. Jenkinson, Dale R. Taylor, et al. "Low-level Hypermutation in T Cell–independent Germinal Centers Compared with High Mutation Rates Associated with T Cell–dependent Germinal Centers." Journal of Experimental Medicine 195, no. 3 (2002): 383–89. http://dx.doi.org/10.1084/jem.20011112.

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Exceptionally germinal center formation can be induced without T cell help by polysaccharide-based antigens, but these germinal centers involute by massive B cell apoptosis at the time centrocyte selection starts. This study investigates whether B cells in germinal centers induced by the T cell–independent antigen (4-hydroxy-3-nitrophenyl)acetyl (NP) conjugated to Ficoll undergo hypermutation in their immunoglobulin V region genes. Positive controls are provided by comparing germinal centers at the same stage of development in carrier-primed mice immunized with a T cell–dependent antigen: NP p
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de Vinuesa, Carola García, Matthew C. Cook, Jennifer Ball, et al. "Germinal Centers without T Cells." Journal of Experimental Medicine 191, no. 3 (2000): 485–94. http://dx.doi.org/10.1084/jem.191.3.485.

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Germinal centers are critical for affinity maturation of antibody (Ab) responses. This process allows the production of high-efficiency neutralizing Ab that protects against virus infection and bacterial exotoxins. In germinal centers, responding B cells selectively mutate the genes that encode their receptors for antigen. This process can change Ab affinity and specificity. The mutated cells that produce high-affinity Ab are selected to become Ab-forming or memory B cells, whereas cells that have lost affinity or acquired autoreactivity are eliminated. Normally, T cells are critical for germi
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He, Yuke, and Carola G. Vinuesa. "Monocytes asphyxiate germinal centers." Immunity 55, no. 3 (2022): 385–87. http://dx.doi.org/10.1016/j.immuni.2022.02.007.

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Young, Clara, and Robert Brink. "Germinal centers and autoantibodies." Immunology & Cell Biology 98, no. 6 (2020): 480–89. http://dx.doi.org/10.1111/imcb.12321.

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Dissertations / Theses on the topic "Germinal centers"

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Dahlenborg, Katarina. "Celluar and molecular aspects of the germinal center reaction." Lund : Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/68945013.html.

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Vonderheide, Robert H. "Formation of germinal centres in the rat." Thesis, University of Oxford, 1988. http://ora.ox.ac.uk/objects/uuid:2a533d75-468a-44b0-a07c-60c6d8f6b17a.

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Wittenbrink, Nicole. "New perspectives on the evolution of B-lymphocytes in germinal centers." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15783.

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Ein zentrales Merkmal der humoralen Antwort ist die im Laufe der Zeit ansteigende Affinität der Antikörper gegenüber dem Antigen, ein Phänomen, das man generell als Affinitätsreifung bezeichnet. Die Affinitätsreifung von Antikörpern ist an die transiente Ausbildung von Keimzentren gebunden, die man nach Immunisierung mit einem T-Zell-abhängigen Antigen in sekundär lymphatischen Geweben wie der Milz beobachtet. Innerhalb der Keimzentren durchlaufen B-Zellen einen mikro-evolutionären Prozess, in dessen Verlauf es zu einer Diversifizierung der von den B-Zellen kodierten B-Zell-Rezeptoren durch so
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Alcantar, Eduardo C. Jr. "IDENTIFYING A POSSIBLE LINK BETWEEN ECTOPIC GERMINAL CENTERS AND THE EVOLUTION OF TYPE I DIABETES." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/348459.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.<br>The multifaceted phenotype of the B‐lymphocyte has a remarkably effective role in peptide derived pathogen clearance and the prevention of re‐infection. This mechanism of host tolerant defense can be attributed to the actions of particular cellular subsets that arise from Blymphocytes: memory cells and high‐affinity antibody secreting plasma cells. Notably B cell propagation does not commence without the help of follicular helper
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Atkinson, Jeffrey Ross. "Peripheral Germinal Centers Regulate Virus-Specific B Cell Accumulation in the CNS." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1524683244217474.

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Goldman, Lea Nichole. "Kinetics and phenotype of the draining lymph node and pulmonary B cell response to an influenza A virus-like particle vaccine." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/4634.

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Influenza A virus (IAV) infection is a serious respiratory disease associated with significant morbidity and mortality worldwide. Annual vaccination is the most effective way to prevent infection and its potentially severe complications; however, the vaccines currently offered have several drawbacks that limit its availability and protective efficacy. Influenza virus-like particles (VLPs), which lack viral genetic material and are non-infectious, represent a promising vaccine candidate. Previous reports have shown VLPs are more immunogenic than subunit or recombinant proteins, and confer prote
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Sakamoto, Keiko. "Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice." Kyoto University, 2016. http://hdl.handle.net/2433/217734.

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Chaimowitz, Natalia. "The role of Fyn and B-cell expressed ADAM10 in early B cell development, germinal center formation and terminal B cell differentiation." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/374.

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In these studies we sought to determine the role of Fyn kinase and ADAM10 in B cell biology. A disintegrin and metalloproteinase 10 (ADAM10) is a zinc dependent proteinase related to matrix metalloproteinases. ADAM10 has emerged as a key regulator of cellular processes by cleaving and shedding extracellular domains of multiple transmembrane receptors and ligands. In particular, ADAM10 has been identified as a key regulator of lymphocyte development. Here we report that ADAM10 is dispensable for early B cell development within the bone marrow. However, deletion of ADAM10 from all peripheral B c
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Hussein, Mourad. "Caractérisation des mécanismes cellulaires, génétiques et épigénétiques de la différenciation terminale des lymphocytes B chez l’homme." Thesis, Rennes 1, 2013. http://www.theses.fr/2013REN1S198.

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Ces dernières années ont été marquées par une progression importante dans la connaissance de la physiologie des cellules B in vivo et de leur différenciation en plasmocytes, grâce aux modèles murins et à l'imagerie intravitale. La transposition à l'Homme des connaissances acquises chez la souris soulève cependant des difficultés, telles que le manque d'outils pour visualiser les évènements qui se déroulent dans les organes lymphoïdes humains. Dans l'optique d'apporter une réponse à cette problématique, nous avons développé au sein du laboratoire un modèle in vitro en deux étapes, permettant la
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Eijk, Martinus Cornelis van. "Regulation of germinal center B cell apoptosis." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/83857.

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Books on the topic "Germinal centers"

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Calado, Dinis Pedro, ed. Germinal Centers. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7095-7.

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Thorbecke, G. Jeanette, and Vincent K. Tsiagbe. The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1.

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Washiyama, Miki. Studies on the cellular contents of human germinal centres. University of Birmingham, 1995.

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Calado, Dinis Pedro. Germinal Centers: Methods and Protocols. Springer New York, 2017.

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Calado, Dinis Pedro. Germinal Centers: Methods and Protocols. Springer New York, 2018.

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Germinal centers in the immune response. Munksgaard, 1992.

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Tsiagbe, Vincent K., and G. Jeanette Thorbecke. Biology of Germinal Centers in Lymphoid Tissue. Springer London, Limited, 2013.

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Tsiagbe, Vincent K., and G. Jeanette Thorbecke. Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin / Heidelberg, 2013.

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Fiore-Donati, L. Lymphatic Tissue and Germinal Centers in Immune Response. Springer, 1995.

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Jeanette, Thorbecke G., and Tsiagbe Vincent Kwaku, eds. The biology of germinal centers in lymphoid tissue. Springer, 1998.

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Book chapters on the topic "Germinal centers"

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Miranda, Roberto N., Joseph D. Khoury, and L. Jeffrey Medeiros. "Progressive Transformation of Germinal Centers." In Atlas of Lymph Node Pathology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7959-8_22.

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de Boer, B. A., I. Voigt, H. J. Kim, et al. "Affinity Maturation in Ectopic Germinal Centers." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57276-0_24.

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Insel, R. A., and M. H. Nahm. "T and B Lymphocytes in Germinal Centers." In The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1_3.

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Przylepa, J., C. Himes, and G. Kelsoe. "Lymphocyte Development and Selection in Germinal Centers." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-71984-4_8.

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Kasajima, T., A. Andoh, Y. Takeo, and T. Nishikawa. "The Localization of Lymphokines in Murine Germinal Centers." In Advances in Experimental Medicine and Biology. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2930-9_62.

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Tsiagbe, V. K., N. M. Ponzio, G. S. Erianne, D. J. Zhang, G. J. Thorbecke, and G. Inghirami. "Germinal Center Derived Lymphomas in Humans and Mice." In The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1_5.

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Reynolds, John D. "Evidence of Differences Between Peyer’s Patches and Germinal Centers." In Microenvironments in the Lymphoid System. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2463-8_13.

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Tsiagbe, V. K., and G. J. Thorbecke. "Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice." In The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1_1.

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Tew, J. G., D. Qin, J. Wu, G. F. Burton, and A. K. Szakal. "The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts." In The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1_2.

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Storb, U. "Somatic Hypermutation of Immunoglobulin Genes." In The Biology of Germinal Centers in Lymphoid Tissue. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-13141-1_4.

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Conference papers on the topic "Germinal centers"

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Shinde, Snehal B., and Manish P. Kurhekar. "Agent based modeling of the process for initiation of Germinal Centers." In 2019 IEEE 5th International Conference for Convergence in Technology (I2CT). IEEE, 2019. http://dx.doi.org/10.1109/i2ct45611.2019.9033817.

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Colafrancesco, Serena, Elena Pipi, Saba Nayar, et al. "SAT0011 TRANSCRIPTOMICS UNVEILS UNIQUE BIOLOGICAL PROFILE OF TERTIARY LYMPHOID STRUCTURES GERMINAL CENTERS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.6993.

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Colafrancesco, S., E. Pipi, J. Campos, et al. "P009/O22 Transcriptomics unveils unique biological profile of tertiary lymphoid structures germinal centers." In 39th European Workshop for Rheumatology Research, 28 February–2 March 2019, Lyon, France. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2018-ewrr2019.6.

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Castrillon, Carlos, Lea Simoni, Theo van den Broek, et al. "202 Transcriptomic diversity and overlapping clonality across subsets of antibody-secreting and memory B cells from spontaneous germinal centers." In LUPUS 21ST CENTURY 2022 CONFERENCE, Abstracts of Sixth Scientific Meeting of North American and European Lupus Community, Tucson, AZ, USA – September 20–23, 2022. Lupus Foundation of America, 2022. http://dx.doi.org/10.1136/lupus-2022-lupus21century.6.

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Pontarini, E., W. Murray-Brown, C. Croia, et al. "OP0300 Enrichment of T follicular-helper cells (TFH) and exclusion of t follicular-regulatory cells (TFR) from ectoPIC germinal centers in salivary glands of sjogren's syndrome patients." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.6121.

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O'Connor, Mark J., Anja E. Hauser, Ann M. Haberman, and Steven H. Kleinstein. "Activated Germinal-Center B Cells Undergo Directed Migration." In 2009 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2009. http://dx.doi.org/10.1109/bibm.2009.61.

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Trabucco, Sally E., and Hong Zhang. "Abstract 2496: YY1 regulates the germinal center reaction by inhibiting apoptosis." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2496.

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Calado, Dinis Pedro. "Abstract IA24: MYC in germinal center B cell physiology and pathology." In Abstracts: AACR Special Conference on Myc: From Biology to Therapy; January 7-10, 2015; La Jolla, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1557-3125.myc15-ia24.

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Solis, Sabrina, Tomoaki Muramatsu, Sophie Gray-Gaillard, and Ramin Herati. "616 Understanding molecular consequences of immunotherapy on the germinal center axis." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.0616.

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Joshi, Ayush. "Design of a parallel immune algorithm based on the germinal center reaction." In Proceeding of the fifteenth annual conference companion. ACM Press, 2013. http://dx.doi.org/10.1145/2464576.2482749.

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