Dissertations / Theses: 'GFCI'

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Rosich, Garrett Kyle. "Evaluation of GLO: a Solar Occultation Instrument for Measuring Atmospheric Trace Species on CubeSat Missions." Thesis, Virginia Tech, 2017. http://hdl.handle.net/10919/78013.

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CubeSats provide an inexpensive means for space-based research. However, optimal mission design depends on minimizing payload size and power. This thesis investigates the GLO (GFCR (Gas Filter Correlation Radiometry) Limb Occultation) prototype, a new small-form-factor design that enables sub-kilometer resolution of the vertical profile of atmospheric trace species to determine radiative influences. This technology improves SWAP (Size, Weight, And Power) over heritage SOFIE and HALOE instruments and provides a cost-effective alternative for solar occultation limb monitoring. A python script was developed to analyze solar intensity through GLO telescope channels. Non-uniform aerosol images used a peak intensity algorithm compared to the edge detection function designed for GFCR channels. Scaling corrections were made for beam splitter inaccuracy and SNR was characterized for frame collection. Different cameras were tested to weigh accuracy versus cost of a camera baffle. Using the Langley plot method, solar intensity versus changes in the solar zenith angle were measured for extrapolation of optical depths. AERONET, a network of ground-based sun photometers measuring atmospheric aerosols, was used for aerosol optical depth validation. Spectral Calculator transmission data allowed for GFCR vacuum channel comparison, gas cell spectral analysis, and gas cell to vacuum channel optical depth examination. Ground testing provided promising results with the low-cost prototype. It will be further evaluated through a balloon flight demonstration using a flight-ready GLO instrument. Additionally, analysis for the DUSTIE mission is planned and simulated using STK and Matlab. This includes CubeSat bus selection, orbit analysis for occultation occurrences, power budgeting, and communication capabilities. Master of Science

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Karsunky, Holger. "Multiple Defekte der Hämatopoese und T-Zellentwicklung in Gfi-1-defizienten Mäusen." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=962762180.

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Osafo, Joy Kwakyewaa. "Regulation of the V1 mRNA variant of the human growth hormone receptor gene by Gfi-1, Gfi-1b, a GAGA element and the liver enriched transcription factor, HNF-4[alpha]." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=102688.

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GH acts through its specific receptor, GHR. In the human liver, more than twelve hGHR mRNAs are transcribed from unique TUTR exons, seven of which are found in two small clusters: module A (V2,V9,V3) and module B (V7,V1,V4,V8). While module A mRNAs are ubiquitously expressed, module B transcripts are restricted to normal postnatal liver, suggesting developmental- and liver-specific regulation of the hGHR gene. To begin characterising the elements regulating module B mRNA expression, I studied the promoter region of the V1 exon, the most abundantly expressing variant in liver. A 1.8 kb region upstream of the V1 transcriptional start site (TSS) was actively repressed in transient transfection assays (TTAs). However, T or 3' deletions relieved the suppression, suggesting the presence of multiple negative and positive regulatory elements. Two sites for growth factor independence-1 (Gfi-1) and Gfi-1b and a GAGA element were identified in the most 3' 300 by regulatory region. Gfi-1 was detected by western blot in human foetal and postnatal liver. Gfi-1 and Gfi-lb strongly repressed while the Drosophila GAGA factor (GAF) stimulated V1 transcription through their specific sites, as determined by TTAs and site-directed mutagenesis (SDM). Six putative sites for hepatic nuclear factor-4 (HNF-4) were also identified in the 1.8 kb region. HNF-4alpha is developmentally regulated in human liver: HNF-4alpha,2 and alpha8 proteins are expressed in foetal hepatocytes but only HNF-4alpha2 is detected postnatally. TTAs and SDM demonstrated that HNF-4alpha2 and HNF-4alpha8 have a similar dual effect on V1 transcription: activation via site #1 in the proximal promoter and repression through site #6, ~1.7 kb upstream of the TSS. Results from EMSA/EMSSA/ChIP analyses suggest these sites are bound by HNF-4alpha. Thus, V1 transcriptional activity is repressed by Gfi-1/Gfi-1b, stimulated through a GAGA element by GAF, and repressed or stimulated by HNF-4alpha. (2+8) depending on the site. Similar sites are present in homologous regions of the bovine, ovine and mouse GHR genes suggesting that their regulatory roles are conserved. However, none of these factors individually appear to be responsible for the postnatal hepatic-specific expression of V1 mRNA. To define the specific regulatory mechanisms, future studies should examine their interactions with additional liverenriched factors (e.g. C/EBPalpha).

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Shepherd, Clare B. "Characterisation of the role of the transcription factor Gfi-1B in haematopoiesis : Clare B. Shepherd." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433107.

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Ilesanmi, Kehinde Damilola. "Systemic risk, financial stability, and macroprudential policy responses in emerging African economies." Thesis, University of Zululand, 2019. http://hdl.handle.net/10530/1992.

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A thesis submitted to the Faculty of Commerce, Administration and Law, in fulfillment of the requirement for the Degree of Doctor of Philosophy in Economics at the University of Zululand, 2019. The extent of the damage caused by the 2007/08 global financial crisis (GFC) has forced policymakers all over the world to respond promptly in order to mitigate its effect, a process in which they are still engaged in, particularly in advanced economies. The main objective of this study is to measure systemic risk in African emerging economies and develop a macroprudential regulatory framework to mitigate or limit the effect of such risk. More specifically, the study intends to1) Developing financial stress index (FSI) for the Emerging African economy; 2) Investigate the possibility of Early Warning Signal (EWS) helping in predicting and preventing or minimising the effects of the crisis on financial institutions; 3) Assess the resilience of individual banking companies to adverse macroeconomic and financial market conditions using stress testing technique; 4) Identify the source of fluctuation within the system; 5) Identify and measure systemic risk emanating from the capital flow (surge) as well as its effects on financial stability. This study contributed to the body of knowledge by measuring systemic risk in emerging African economies. To the best of my knowledge, there have not been any studies that have been conducted for the measure of systemic risk with the context of emerging African economies. The target economies include South Africa, Egypt, Nigeria, and Kenya. The first objective of the study is to construct a financial stress index (FSI) for emerging African economies. The FSI which is aimed at revealing the functionality of the financial system a single aggregate indicator that is constructed to reflect the systemic nature of financial instability and as well to measure the vulnerability of the financial system to both internal and external shocks. The result shows that both the domestic and international shocks created uncertainty in the economies under consideration. On the international scene, we have the financial crisis while on the domestic scene; we have slow growth, banking crisis, energy crisis, labour crisis, coupled with political uncertainty. The FSI is also useful and appropriate as the dependent variable in an early signal warning model, and as well be used to gauge the effectiveness of government measures to mitigate financial stress. The models forecasting performance was tested using the ordinary least square methods and it affirmed that the model is reliable and that the FSI can be used for prediction of a future crisis. v The aim of the second objective is to develop an early warning signal (EWS) model to predict the possibility of the occurrence of a financial crisis in emerging African countries. The multinomial logit model built by Bussiere and Fratzscher (2006) was adopted to afford policy makers ample time to prevent or mitigate potential financial crisis. In summary, the result suggests that emerging African economies are more likely to face financial crisis as debts continue to rise without a corresponding capacity to withstand capital flow reversal as well as excessive FX risk due to currency exposure. The result further indicates that rising debt exposure increases the probability or likelihood of the economies remaining in a state of crisis. This result confirms the significance of a financial stability framework that fits Africa’s emerging economies characteristics such as rising debt profile liquidity and currency risk exposure. The third objective is to test the resilience of the financial sector using stress testing technique. Macro stress testing is a multi-step simulation process aimed at estimating the impact of credit risk shock on macroeconomic as well as financial sectors. In this study, a two-step approach was employed in this chapter. The first step involves analyzing the determinants of credit risk in 4 Emerging African economies during the period 2006m1 to 2012m12 using the panel Auto Regressive Distribution Lag (ARDL) model. Second, the vector autoregressive (VAR) models were employed to assess the resilience of the financial system as well as the economy to adverse credit risk shocks. The result shows that all the variables under both the macro and financial model jointly determine credit risk, although when examined on an individual basis only, UMP, IBR, and INF have a significant impact on NPL in the long run. For the macro stress testing, the VAR methodology was employed to stress test the emerging African economy financial sector and the result indicated that there a significant relationship between changes in output gap (GAP) and the nonperforming loans. A significant relationship was also established between inflation and nonperforming loans. In all, South Africa and Nigeria’s financial system seems more resilient to credit losses associated with this scenario without threatening financial stability compared to Kenya and Egypt. The fourth objective examined the sources of capital flows surge and their impact on macroeconomic variables. This study employed a ��−�� to investigate the source capital flow surge within the system. The main findings of the result indicate that capital flow, which is vi proxied by FDI, is influenced by a wide variety of macroeconomic variables such as inflation, export growth and unemployment. There is therefore need for the implementation of capital controls framework tame massive capital inflows. Nevertheless, such a mechanism should not undermine the impact of capital inflows on employment, growth and financial stability. The fifth objective of the study is aimed at identifying and measuring the sources of systematic risk and its impact on the stability of the financial system using the Conditional Value-at-Risk methodology. The main finding of the study indicates that at the normal and extreme event the banking sector contributes positively and significantly to the real economy for all the countries except for Nigeria at the extreme event or 1 percent quantile. This study, therefore, concludes that the banking sector, stock market volatility contributes greatly to systemic risk in emerging African economies. The individual bank also contributes significantly to systemic risk for all the economies although the magnitudes are relatively different across economies. This finding is of great interest to policymakers since it shows that the banking sectors as well as stock market volatility have a negative impact on the real economy. This result is plausible as the banking and financial sector for most emerging economies constitute a greater proportion of the real economy. There is, therefore, need for a regulatory framework to reduce risk emanating from the banking sector as well as the financial markets. In summary, due to huge capital flows and rising debt level in emerging African economies, there is, therefore, a need for a macroprudential policy that will fit African economies as well as the implementation of capital controls framework tame massive capital inflows. Efforts should be made to reduce the rising debts profile of most countries and that will require a greater level of commitment from their respective government and central banks. However, these should be in the interest of the growth and stability of the financial system and the real economy at large. In the case of the banking sector, since it has a great impact on triggering systemic risk, more effort should be utilized to continue to monitor its performance so that potential risk can be detected early and nip in the bud.

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Laurent, Benoît. "Fonctions et modes d'action du facteur de transcription Gfi-1B au cours de l'érythropoïese normale et pathologique." Paris 5, 2009. http://www.theses.fr/2009PA05T029.

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L'érythropoïèse, processus de formation des érythrocytes à partir de cellules souches hématopoïétiques, requiert l'activation d'un programme transcriptionnel spécifique. Le facteur de transcription répresseur Gfi-1B est essentiel au bon déroulement de l'érythropoïèse puisque les souris invalidées pour ce gène meurent in utero par absence totale d'hématies. L'objectif de mes recherches doctorales était de caractériser les fonctions et les modes d'action du facteur de transcription Gfi-1B au cours de l'érythropoïèse adulte. Mes résultats montrent : l/ que l'expression de Gfi-1B augmente dans les stades initiaux et reste élevée jusqu'aux stades terminaux de la différenciation érythroïde adulte humaine. La diminution du recrutement des co-répresseurs de Gfi-1B au niveau de son propre promoteur permet le maintien de son activité transcriptionnelle au cours de la différenciation érythroïde. Il que la protéine HMGB2 est indispensable à l'érythropoïèse en contrôlant le niveau d'expression de Gfi-1B. 3/ que Gfi-lB est indispensable à l'érythropoïèse au niveau des progéniteurs bipotents érythro-mégacaryocytaires en régulant la signalisation TGF-(3 via le contrôle de l'expression du récepteur de type III du TGF-P, un gène cible de Gfi-1B. 4/ que la répression transcriptionnelle par le complexe LSDl/CoREST/HDAC nécessite la méthylation d une isoforme de Gfî-lB. De manière intéressante, une diminution d'expression de Gfi-1B et de son isoforme ont été mis en évidence chez la plupart des patients myelodysplasiques Erythropoiesis, process of erythrocytes production from hematopoietic stem cells, involves the activation of a specific transcriptional program. The transcriptional represser Gfi-1B is essential for erythropoiesis as mice knocked-out for this gene die in utero because of an absence of red cells. The aim of my doctoral researches was to study and characterize functions and actions of the transcription factor Gfi-1B during adult erythropoiesis. My results have shown: II that Gfi-1B expression increases strongly during erythroid differentiation and stays high till terminal stages. Decrease of Gfi-1B co-repressor recruitment on its own promoter allows its transcriptional activity throughout erythroid differentiation. 2/ that HMGB2 protein is necessary for erythropoiesis by controlling Gfi-1B expression 3/ that Gfi-1B is necessary at the bipotent erythro-megakaryocytic progenitor stage by regulating TGF-P signalling via the control of the expression of TGF-P receptor type III, a Gfi-1B target gene. 4/ that transcriptional repression by the LSDl/CoREST/HDAC complex involves the methylation of a Gfi-1B isoform. Interestingly, a decrease hi the Gfi-1B expression and its isoform was shown in most of the erythroid progenitors from myelodysplasic patients

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Mian, Daniyal. "A model to assess the impact of innovation activity on project performance in consulting engineering firms." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/88954/4/Daniyal_Mian_Thesis.pdf.

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A holistic consideration of innovation and associated activities is still very new to consulting engineering firms. This research will have benefits for both industry and academia. The final outcome of this research is a prioritised decision making innovation model that can be used by consulting engineering firms to make informed decisions by investing in appropriate innovation activities that positively impact project performance. This helps by using an informed approach towards investing rather than 'hit-and-miss' trialling.

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Qingquan, Liu. "Investigating the mechanisms of growth factor independence-1 (Gfi-1)-mediated transcriptional repression of p21Cip1 and MBP." Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1241726388.

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Dissertation (Ph.D.)--University of Toledo, 2009. Typescript. "Submitted as partial fulfillment of the requirements for The Doctor of Philosophy in Biology." "A dissertation entitled"--at head of title. Title from title page of PDF document. Bibliography: p. 84-97.

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Sheppard, Allan Stanley. "A Capability Model to Understand In-Field Responses to Natural Disaster Relief in the Developing World." Thesis, Griffith University, 2013. http://hdl.handle.net/10072/366746.

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Humanitarian logistics has grown as a field of research since 2004 through the impact of the Indian Ocean tsunami (Kovács & Spens, 2011). The literature has focused on the increasing costs of natural disasters in terms of the number of casualties among the affected people and the heavy economic losses. These economic losses come at a time when international instability resulting from the Global Financial Crisis (GFC) has led to many nations focusing on their own financial plights. As a result, the level of financial support for international aid has significantly decreased (Dabla-Norris, Minoiu, & Zanna, 2011). Many international humanitarian agencies are finding it more difficult to maintain and retain experienced personnel trained in humanitarian logistics and response to natural disasters (Thomas, 2003; Thomas & Kopczak, 2005). A number of national governments of developing countries are taking more responsibility for managing natural disasters in their own countries, utilising the capacity of their local populations (Kent, 2012). Although local populations are proving to be quite capable, particularly as first responders, they often require technical and financial support to respond effectively to natural disasters (Widmer, 2003). Thesis (PhD Doctorate) Doctor of Philosophy (PhD) Griffith Business School Griffith Business School Full Text

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Do, Thi Tuan Anh. "Modelling cross-market linkages between global markets and China’s A-, B- and H-shares." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2020. https://ro.ecu.edu.au/theses/2344.

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One of the biggest challenges in quantifying joint risk and forming effective policies in financial management and investment strategies is to fully understand the characteristics of market associations in low and high volatility periods. Market interdependence, therefore, is a hot topic that has received interest from academics and industry experts, especially since the Asian Financial Crisis in 1997. China, being the world’s second-largest economy, has been the centre of many studies investigating stock market dependencies. While China has three major share types, namely A-, B- and H-shares, with different market players, market characteristics and operating efficiency, the number of studies on each of these share types remains conservative in comparison to the vast literature on the financial modelling of market interdependencies. Given the need for a more comprehensive understanding of the influence between these share types and other global markets, especially during market turbulences, this thesis examines the cross-market linkages between A-, B- and H-shares in China and several major emerging and advanced markets from 2002 to 2017, which is divided into two non-crisis periods and two crisis periods. This thesis assesses market integration among 17 markets, including asymmetries and leverage effect in the marginal distributions, volatility spillover and tail dependence. The thesis aims to: 1) investigate the univariate asymmetries and leverage effect in the distributional volatility of each time series and to detect volatility spillover between China and other studied markets; 2) assess the dynamic multivariate dependence between China and other studied markets; 3) evaluate the bivariate dependence structure for each of China’s markets and other studied markets using seven different copula functions; and 4) study the multivariate joint tail dependence structure of all studied markets using vine copulas. There are various findings from the thesis. Many advanced and emerging markets experienced leverage effect and asymmetries in volatility. China’s markets were much more prone to local shocks than external shocks and in many cases, there is evidence that China’s markets diverged from the global trends especially during the crisis periods. Besides, segmentation between China’s markets and the United States is clearly evident. In addition, regional dependence is stronger than intra-regional dependence. The thesis also found the existence of contagion effect between each of China’s markets and various markets in the sample in the Global Financial Crisis. Finally, heterogeneity was found for A-, B- and H-shares in various aspects, from distributional asymmetries to joint behaviour in both crisis and non-crisis periods. A novel aspect of this thesis is that it closes the gap in the literature of market linkages for A-, B- and H-shares with other global markets by assessing volatility spillover, time-varying co-movement, and tail dependence among the studied markets. This thesis provides various implications in both theoretical and empirical contexts in many areas including measuring joint risk at the tails, constructing an optimal portfolio, hedging, and managing financial exposures and contagious volatility from other markets. The thesis provides some recommendations and suggestions regarding the policies implemented in China.

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Nagy, Alexandra [Verfasser], and Andreas [Akademischer Betreuer] Burchert. "Untersuchung der Expression des nukleären Onkogens SKI und des Transkriptionsrepressors GFI bei der akuten myeloischen Leukämie / Alexandra Nagy. Betreuer: Andreas Burchert." Marburg : Philipps-Universität Marburg, 2015. http://d-nb.info/1080298347/34.

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Lee, Soojin. "Structure and dynamics in proteins Part I. Structural origins of specific DNA recognition by GFI-1 ; Part II. Structural and dynamic studies of [gamma]S-crystallin and OPJ, implications for cataract formation /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1189025356.

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Lee, Soojin. "Structure and dynamics in proteins: Part I. structural origins of specific DNA recognition by GFI-1 Part II. structural and dynamic studies of γS-crystallin and OPJ, implications for cataract formation". The Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=osu1189025356.

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Bulhões, Rodrigo de Souza. "Contribuições à análise de outliers em modelos de equações estruturais." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/45/45133/tde-19062013-135858/.

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O Modelo de Equações Estruturais (MEE) é habitualmente ajustado para realizar uma análise confirmatória sobre as conjecturas de um pesquisador acerca do relacionamento entre as variáveis observadas e latentes de algum estudo. Na prática, a maneira mais recorrente de avaliar a qualidade das estimativas de um MEE é a partir de medidas que buscam mensurar o quanto a usual matriz de covariâncias clássicas ou ordinárias se distancia da matriz de covariâncias do modelo ajustado, ou a magnitude do afastamento entre as funções de discrepância do modelo hipotético e do modelo saturado. Entretanto, elas podem não captar problemas no ajuste quando há muitos parâmetros a estimar ou bastantes observações. A fim de detectar irregularidades no ajustamento resultantes do impacto provocado pela presença de outliers no conjunto de dados, este trabalho contemplou alguns indicadores conhecidos na literatura, como também considerou alterações no Índice da Qualidade do Ajuste (ou GFI, de Goodness-of-Fit Index) e no Índice Corrigido da Qualidade do Ajuste (ou AGFI, de Ajusted Goodness-of-Fit Index), ambos nas expressões para estimação de parâmetros pelo método de Máxima Verossimilhança, que consistiram em substituir a tradicional matriz de covariâncias pelas matrizes de covariâncias computadas com os seguintes estimadores: Elipsoide de Volume Mínimo, Covariância de Determinante Mínimo, S, MM e Gnanadesikan-Kettenring Ortogonalizado (GKO). Através de estudos de simulação sobre perturbações de desvio de simetria e excesso de curtose, em baixa e alta frações de contaminação, em diferentes tamanhos de amostra e quantidades de variáveis observadas afetadas, foi possível constatar que as propostas de modificação do GFI e do AGFI adaptadas pelo estimador GKO foram as únicas que conseguiram ser informativas em todas essas situações, devendo-se escolher a primeira ou a segunda respectivamente quando a quantidade de parâmetros a serem estimados é baixa ou elevada. The Structural Equation Model (SEM) is usually set to perform a confirmatory analysis on the assumptions of a researcher about the relationship between the observed variables and the latent variables of such a study. In practice, the most iterant way of evaluating the quality of the estimates of a SEM comes either from procedures of measuring how distant the usual classic or ordinary covariance matrix is from the covariance matrix of the adjusted model, or from the magnitude of the hiatus in discrepancy functions of both the hypothetical model and the saturated model. Nevertheless, they may fail to capture problems in the adjustment in the occurrence of either several parameters to estimate or several observations. This study included indicators known in the literature in order to detect irregularities in the adjustment resulting from the impact caused by the presence of outliers in the data set. This study has also considered changes in both the Goodness-of-Fit Index (GFI) and the Adjusted Goodness-of-Fit Index (AGFI) in the expressions for parameter estimation by Maximum Likelihood method, which consisted in replacing the traditional covariance matrix by the robust covariance matrices computed through the following estimators: Minimum Volume Ellipsoid, Minimum Covariance Determinant, S, MM and Orthogonalized Gnanadesikan-Kettenring (OGK). Through simulation studies on disturbances of both symmetry deviations and excess kurtosis in both low and high fractions of contamination in different sample sizes and quantities of affected observed variables it has become clear that the proposals of modification of both the GFI and the AGFI adapted by the OGK estimator were the only ones able to be informative in all these situations. It must be considered that GFI or AGFI must be used when the number of parameters to be estimated is either low or high, respectively.

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Probohudono, Agung Nur. "A comparative analysis of voluntary risk disclosures." Thesis, Curtin University, 2012. http://hdl.handle.net/20.500.11937/2132.

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This thesis examines voluntary risk disclosures from 600 firm year annual reports in four countries’ (Australia, Indonesia, Malaysia, and Singapore) manufacturing listed companies for the 2007-2009 financial years. This is an important time span to investigate risk disclosures as it encompasses those years most directly impacted by the Global Financial Crisis (GFC). Longitudinal and cross country analyses test the veracity of agency theory to predict the level of firms’ risk disclosures. A comprehensive risk disclosure index (RDI) checklist is created and tested to explain the extent of such communication over time. T-tests, ANOVA, correlations and regression analysis are used for the statistical testing.The findings show that overall RDI scores over the economically-challenging GFC time period is relative low averaging 33.73%. The RDI rises every year ranging from 31.46% in 2007, 34.20% in 2008, and 35.54% in 2009. There is a vast disparity of communication across the various risk elements. The RDI item “Identifying, evaluating and managing significant risks” has the highest level of communication (91.17%), while “Effects of inflation on assets quantitative’’ is the lowest RDI item with no disclosure (0 %). The highest major sub-category for RDI is business risk (46.55%) while the strategy risk category (17.21%) is the lowest communicated.Multiple regression analysis provides evidence that size, managerial ownership, board independence, and profitability are positively associated with the extent of voluntary risk disclosure. There are also clear country differences, for instance, Indonesian companies have statistically lower levels of risk disclosure compared with Malaysia. These findings are useful for self-evaluation and benchmarking of risk communication by other corporations across the global landscape. The need for mandatory regulation regarding key risks elements is advanced. Overall, varying levels of risk disclosure over time and across countries are influenced by key firm characteristics and economic drivers consistent with agency theory tenets.

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Dibley-Maher, Paul. "Friend or foe? The impact of the Hawke/Keating neoliberal reforms on Australian workers and the Australian public sector." Thesis, Queensland University of Technology, 2012. https://eprints.qut.edu.au/54641/1/Paul_Dibley-Maher_Thesis.pdf.

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Over the last three decades neoliberalism has transitioned from occupying the margins of economic policy debate to becoming the dominant approach by governments and their economic advisers, a process that has accelerated with the collapse of the former Stalinist states in Eastern Europe and the Soviet Union. This thesis adopts a Marxist framework for understanding this process, beginning as it did in the realm of relatively abstract philosophical and ideological debate to the permeation of neoliberal values throughout all capitalist institutions, including the state bureaucracy. This necessarily means a focus on the dialectical relationship between the rise of neoliberalism and the shifting balance of class forces that accompanied the success of the neoliberal project in transforming the dominant economic policy paradigm. The extent to which neoliberal reforms impacted on workers and public sector institutions, along with the success or otherwise of traditional working class institutions in defending the material interests of workers will therefore be a recurring theme throughout this body of work. The evidence borne from this research and analysis suggests a major shift in the dialectic of class struggle in favour of the power of capital over labour during the period covered, with the neoliberal age being one of defeat for a labour movement that largely failed to adopt successful strategies for defending itself.

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Shafei, Afshin. "Geomorphological characterization of fluvial flood hazard across the island of Oahu, Hawaii (USA)." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021.

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Assessing floods hazard is critical to preventing damages and acting fast when a flood event occurs. Flood hazard assessment can be costly, time-consuming, and complex due to running complicated hydrodynamic models of rivers and floodplain systems. Besides, several model runs are normally necessary because different scenarios over large areas must be analyzed for a full characterization of flood hazards. To solve this problem and make the analysis easier with less cost and time, we can use machine-learning techniques. Machine-learning and data-driven methods can be the best alternative way to conventional methods because of their simplicity, faster processing, handling large amounts of data, and more importantly, learning from the past datasets and models to improve themselves. In this Thesis, data-driven DEM-based algorithms developed with the SaferPlaces project (funding: European Commission through EIT Climate-KIC) have been applied to analyze the fluvial and pluvial floods across Oahu island, USA.

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Magnini, Andrea. "Indici morfometrici per la mappatura della pericolosità idraulica da allagamento fluviale a scala regionale: limiti e potenziale." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/19803/.

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La mappatura della pericolosità idraulica costituisce un ambito di ricerca estremamente attuale a causa degli ingenti danni causati ogni anno dalle alluvioni, sia a scala globale che europea. Un ambito di indagine molto popolare è la sperimentazione di metodi di mappatura speditivi, detti DEM-based, privi dei costi e degli oneri computazionali dei tradizionali modelli idraulici. Tali metodi sfruttano come dati in input i modelli digitali delle quote del terreno (DEM), oggi facilmente reperibili, e ne derivano indicatori geomorfici di propensione all’allagamento, che vengono infine impiegati per ottenere mappature binarie della pericolosità idraulica. Il presente elaborato analizza le performance dei metodi DEM-based. La prima parte si occupa del confronto tra diversi indici geomorfici proposti in letteratura, utilizzando come area d’interesse l’Italia Settentrionale; la seconda si concentra sull’indice più promettente, il GFI (Geomorphic Flood Index), applicandolo a tre casi studio, con diversi DEM e modalità di calibrazione. L’analisi dei risultati, conferma l’utilità dei metodi DEM-based, ed in particolare del GFI. Si osserva un miglioramento della mappatura in conseguenza all’aumento della risoluzione del DEM ed alla riduzione delle aree di calibrazione alle zone in prossimità delle aste fluviali. Si evidenziano invece i limiti del GFI nella rappresentazione di complesse condizioni al contorno a scala di dettaglio. Si conclude che i metodi DEM-based sono buoni descrittori della pericolosità idraulica, complementari ai modelli tradizionali; essi trovano la loro naturale applicazione nella mappatura della pericolosità idraulica su ampie aree geografiche.

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Larsson, Alm Kevin. "Automatic Speech Quality Assessment in Unified Communication : A Case Study." Thesis, Linköpings universitet, Programvara och system, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-159794.

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Speech as a medium for communication has always been important in its ability to convey our ideas, personality and emotions. It is therefore not strange that Quality of Experience (QoE) becomes central to any business relying on voice communication. Using Unified Communication (UC) systems, users can communicate with each other in several ways using many different devices, making QoE an important aspect for such systems. For this thesis, automatic methods for assessing speech quality of the voice calls in Briteback’s UC application is studied, including a comparison of the researched methods. Three methods all using a Gaussian Mixture Model (GMM) as a regressor, paired with extraction of Human Factor Cepstral Coefficients (HFCC), Gammatone Frequency Cepstral Coefficients (GFCC) and Modified Mel Frequency Cepstrum Coefficients (MMFCC) features respectively is studied. The method based on HFCC feature extraction shows better performance in general compared to the two other methods, but all methods show comparatively low performance compared to literature. This most likely stems from implementation errors, showing the difference between theory and practice in the literature, together with the lack of reference implementations. Further work with practical aspects in mind, such as reference implementations or verification tools can make the field more popular and increase its use in the real world.

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Montello, Aaron David. "An Experimental Investigation of Water Droplet Growth, Deformation Dynamics and Detachment in a Non-Reacting PEM Fuel Cell via Fluorescence Photometry." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228248650.

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Hallatschek, Werner. "Die Regulation des humanen Lipopolysaccharid bindenden Proteins (hLBP)." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2005. http://dx.doi.org/10.18452/15202.

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Das Lipopolysaccharid Bindende Protein (LBP) ist ein überwiegend in der Leber synthetisiertes Akutphaseprotein. Es bindet den Zellwandbestandteil Lipopolysaccharid (LPS) Gram-negativer Bakterien und transportiert es zu zellulären Rezeptoren, wodurch das angeborene Immunsystem aktiviert wird. In dieser Arbeit wird die Regulation der LBP-Expression in Interleukin (IL)-1, IL-6 und Dexamethason (Dex) stimulierten humanen Hepatomzelllinien HuH-7 und HepG2 untersucht. Der wichtigste Stimulator ist dabei IL-6, dessen Wirkung über die Transkriptionsfaktoren (TF) Stat-3, C/EBP-beta und AP-1 vermittelt wird. Für alle 3 TF konnten aktive Bindungsstellen auf dem LBP-Promotor nachgewiesen werden. Für IL-1-Effekte die u. a. über den TF NF-kappaB vermittelt werden, konnten ebenfalls aktive Bindungsstellen nachgewiesen werden. Die Wirkung von Dex wird über Glucocorticoid Responsive Elements (GREs) vermittelt. Auf dem LBP-Promotor befinden, sich wie gezeigt werden konnte, mehrere aktive GREs, wobei einige verstärkend und einige hemmend wirken. Eine zu beobachtende Synergiewirkung von Dex und IL-6 wird durch die Aufregulation des IL-6-Rezeptors durch Dex verursacht. Die LBP-Expression kann durch TGF (Transforming Growth Factor)-beta gehemmt werden. Der TGF-beta-Signalweg über Smads ist in den Hepatomzellen aktiv, vermittelt aber nicht den TGF-beta-Hemmeffekt, sondern eine geringe stimulierende Wirkung, die bei alleiniger TGF-beta-Inkubation auftritt. Die inhibierende Wirkung von TGF-beta wird durch Gfi-1- und AP-1-Bindungsstellen vermittelt. Die Gfi-1-Bindungsstelle nimmt dabei, wie hier erstmals gezeigt werden konnte, eine herausragende Stellung ein. Die Aufklärung der LBP-Regulation und dabei besonders die Hemmung der LBP-Expression kann mittelfristig dazu beitragen, den klinischen Verlauf von inflammatorischen und infektiösen Erkrankungen zu beeinflussen und bietet daher Potenzial für neue Therapieansätze. Lipopolysaccharide (LPS) binding protein (LBP) is an acute phase protein with the ability to bind and transfer LPS of Gram-negative bacteria. This soluble pattern recognition molecule represents an important defense principle of the host. Regulation of the hepatic acute phase response and its termination are important mechanisms for limiting systemic inflammatory activity of the host. Here were analyze the cooperation of Interleukin (IL)-1, IL-6, and Dexamethasone (Dex) at LBP expression in the hepatoma cell lines HuH-7 and Hep G2. The major inducer of LBP expression is IL-6. Within the LBP promoter numerously highly consensus binding sites such as AP-1, C/EBP-beta? and STAT3 are present, that confer transcriptional activity as shown by truncation and mutation experiments. Additionally, activate NF-kappaB sites activated by IL-1 were detected at the LBP promoter. By mutation experiments of the promoter furthermore were found differentially active glucocorticoid response elements (GREs). The promoter contains GREs enhancing the activity as well as inhibitory ones. The enhancing effect towards LBP expression by Dex was mediated by IL-6. Dex stimulated the expression of the IL-6 receptor and therefore upregulated the IL-6 pathway. Transforming Growth Factor (TGF)-beta is able to inhibit LBP expression in stimulated cells. An AP-1 binding site was identified mediating inhibitory TGF-beta effects towards LBP promoter activity. Furthermore it was shown that a growth factor independence (Gfi)-1 binding site localized near the AP-1 site is essential for mediating the TGF-beta inhibitory effect. The relevancy of the Gfi-1 site fore mediating TGF-beta effects indicates a novel mechanism for understanding inhibitory TGF-beta effects at the transcriptional level. In summary the complex regulation of LBP were elucidate which may help to eventually develop novel intervention strategies for acute phase, sepsis, and septic shock.

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Georgiou, Jonathan. "Exploring the benefits of attracting, recruiting and retaining mature age employees up to and beyond the traditional age of retirement: Perspectives from Western Australia." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2015. https://ro.ecu.edu.au/theses/1632.

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There has been a recent upsurge in media attention surrounding Australia’s ageing workforce. A review of academic, media and grey literature highlighted inadequacies in existing workplace polices, as well as flaws in financial and social security schemes. Of particular concern were persistent negative attitudes and counterproductive policies regarding mature age employees (MAEs). Poor retention rates among this cohort of workers aged 45 years and over are leading to skilled labour shortages and losses in corporate knowledge. This expected mass exodus of mature cohorts into retirement has been predicted to negatively impact the socio-economic sustainability of ageing societies world-wide and is a pertinent issue for Western Australia (WA). The overarching objective of this study was to identify the ‘place’ of mature cohorts within WA workplaces and promote strategies that will improve the employment conditions and overall quality of life of ageing workforces. Research questions aimed to address the need for greater mature age employment up to and beyond pensionable age; identify ‘gaps’ in policies and programmes; and explore how mature cohorts were perceived (valued) and the extent their departure may affect WA society (labour force). By using a mixed methods research design, this Doctoral dissertation developed a conceptual framework for limiting significant issues individuals, businesses and society may experience as a result of WA’s ageing workforce; whilst simultaneously promoting the benefits of maturity and mature age employment. This Re-Model draws upon the community development work principles of social justice, empowerment and social capital; and is further contextualised by methods of best practice identified from the triangulation of secondary sources, quantitative data and qualitative inquiry. Primary data collection involved the completion of 362 surveys, followed by 27 semistructured interviews and four focus group activities, with a cross section of MAEs, volunteers, their employers, retirees and unemployed cohorts from across WA. Over one-third of current MAEs, employers and volunteers in this study reported they intended working later than the traditional age of retirement, with 71 per cent of this sample planning to semi-retire. Furthermore, almost 60 per cent of a sample that had previously exited the labour force was working at the time of data collection as semi-retirees or rehired retirees (rehirees). Collectively, these statistics indicated that despite predictions of mass disengagement among mature cohorts, most of this crosssection of Western Australians are seeking to remain in (or re-enter) the WA workforce beyond pensionable age. However, quantitative and qualitative findings revealed several barriers to their continued engagement, including access to ‘age-friendly’ workplaces; a dearth of targeted training (career) development and employment assistance; and a lack of value attributed to mature age skills and experience, particularly deleterious in WA’s youth-centric culture. Primary data also highlighted several enabling factors for mature age employment. ‘Flexibility’ and ‘autonomy of choice’ were cited as key dimensions across all aspects of paid work, volunteering and retirement – whether in terms of worklife- balance; the individuation of training and development; or options available to those transitioning out of traditional employment. Data indicated that sustainable cultural change required more than just the removal of negative policies or introduction of punitive legislation. Maintaining a positive outlook among mature age individuals and simultaneously educating (younger) co-workers, employers, policy-makers (stakeholders) and society about the virtues of maturity and non-traditional work (skills) were considered essential to changing societal attitudes, behaviour and culture.

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Huang, Duen-Yi. "Regulation of the Gfi-1B Expression in K562 Cells." 2005. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-2501200510021200.

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Huang, Duen-Yi, and 黃婷茵. "Regulation of the Gfi-1B Expression in K562 Cells." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/56841454574593364521.

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博士 國立臺灣大學 生物化學暨分子生物學研究所 93 Abstract Gfi-1B（growth factor independence-1B）is a proto-oncogene that encodes a transcriptional repressor with an N-terminal SNAG repressor domain and a C-terminal zinc finger domain. Expression of Gfi-1B is restricted to erythroid lineage cells and is essential for erythropoiesis. As Gfi-1B is highly expressed in the erythroid lineage chronic myelocytic leukemia (CML) line K562, this study aims to understand how the expression of Gfi-1B is regulated in K562 cells. Toward understanding the transcriptional control of the human Gfi-1B gene, I first defined its transcription start site. By using oligo-capping method, its first non-coding exon of Gfi-1B gene was found to be approximately 7.82 kb upstream of the first coding exon. The genomic sequence preceding this first non-coding exon has been identified to be its erythroid-specific promoter region in K562 cells. Using gel-shift and chromatin immunoprecipitation (ChIP) assays, I have demonstrated that NF-Y and GATA-1 directly participate in transcriptional activation of Gfi-1B gene in K562 cells. Ectopic expression of GATA-1 markedly stimulates the activity of Gfi-1B promoter in a non-erythroid cell line U937. Interestingly, this GATA-1-mediated trans-activation not only is dependent on its binding to the promoter, but also requires transcription factor NF-Y binding to the CCAAT site. Thus, functional cooperation between GATA-1 and NF-Y contributes to erythroid-specific transcriptional activation of Gfi-1B promoter. The expression of many eukaryotic transcription factors has been shown to be autoregulated positively and negatively. To further investigating the effect of Gfi-1B on its own promoter. By ectopic expression of Gfi-1B in K562 cells, I have demonstrated that the transcription of Gfi-1B is negatively regulated by its own gene product. GATA-1, instead of Gfi-1B, binds directly to the Gfi-1-like sites in the Gfi-1B promoter, and Gfi-1B suppresses GATA-1-mediated stimulation of Gfi-1B promoter through their protein interaction. These results not only demonstrate that expression of Gfi-1B is negatively autoregulated through GATA-1, but also suggest that Gfi-1B can modulate transcription in erythroid-type cells without its direct interaction with the Gfi-1 site of the target genes. Here, I propose that this negative autoregulatory feedback loop provides a mean to restrict the expression level of Gfi-1B, thus limiting its inhibitory effect on GATA-1-mediated transcription necessary for erythroid differentiation. In addition to GATA-1 mediated transcription, I also found that Gfi-1B expression in K562 cells is controlled by post-transcriptional and post-translational regulation. RNA transcript and polypeptide of Gfi-1B were found to be destabilized in response to phorbol ester (PMA) treatment in K562 cells. Degradation of Gfi-1B protein is through the ubiquitin-proteasome-mediated pathway. During PMA treatment, Gfi-1B became phosphorylated in its PEST containing region. However, the phosphorylation on PEST sequence is not a requisite signal for Gfi-1B degradation during PMA treatment in K562 cells. In summary, the results obtained from this study indicated that multiple layers of regulation interplay to confer a tight regulation on Gfi-1B expression in K562 cells.

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Oliveira, Maria Francisca Pranto de. "A Gestão da Formação na Gfi Portugal: Tecnologias de Informação." Master's thesis, 2020. http://hdl.handle.net/10400.26/34586.

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O presente relatório de estágio curricular surge no âmbito da conclusão do ciclo de estudos de mestrado em Gestão de Recursos Humanos na Universidade Europeia. O estágio foi realizado no departamento de Recursos Humanos da empresa de outsourcing multinacional Gfi Portugal – Tecnologias de Informação, sendo que a área do estágio teve foco na gestão e operacionalização da formação da empresa. Assim, o presente documento engloba uma revisão de literatura da temática visada, a descrição da organização e das atividades desenvolvidas ao longo do estágio, concluindo com um balanço crítico do mesmo.

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Pereira, Elsa Alexandra da Mota. "Responsabilidade social das empresas: estudo de caso da Gfi Portugal." Master's thesis, 2017. http://hdl.handle.net/1822/46529.

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Dissertação de mestrado em Economia Social Esta investigação incidiu na dissertação do conceito de responsabilidade social das empresas, tendo como estudo de caso uma empresa portuguesa ligada às tecnologias de informação - a Gfi Portugal. O principal objetivo do estudo foi perceber qual a perceção dos stakeholders da Gfi Portugal relativamente à abrangência, à eficácia e à motivação da RS da empresa. Uma empresa é socialmente responsável quando, cumulativamente, toma ações que visam a integração de preocupações sociais, como a justiça social ou a qualidade ambiental, no seu modelo de gestão, realiza estas iniciativas de modo voluntário, orienta o seu negócio no sentido do desenvolvimento sustentável da sociedade, com particular atenção aos seus stakeholders, e assume as responsabilidades pelo seu impacto. Nesta medida, concluiu-se que a Gfi Portugal é uma empresa socialmente responsável, sendo este um dos seus valores institucionais. Neste estudo, foram inquiridos 161 indivíduos, representantes dos stakeholders da Gfi Portugal, incluindo-se nesta amostra trabalhadores da empresa e beneficiários das iniciativas de RS promovidas pela mesma. Através da análise das suas respostas, concluiu-se que a RS da Gfi é percecionada como estando situada entre o nível médio e o nível bom. Desta forma, a perceção existente é a de que as iniciativas propostas pela empresa são abrangentes, eficazes e prendem-se por motivações altruístas e integrativas. Contudo, e apesar de considerarem a temática importante, mesmo ao ponto de atribuírem ao caráter ético da empresa um peso igualitário ao da remuneração na escolha de um trabalho, os funcionários não têm um envolvimento real com as ações de RS, sendo a taxa de participação nestas muito fraca. Em suma, observou-se que, apesar dos stakeholders da empresa reconhecerem a importância do conceito e fazerem uma avaliação positiva do exercício da RS por parte da empresa, há espaço para melhorias ao nível da comunicação da prática aos trabalhadores de modo a ser construído um maior engagement entre estes e a responsabilidade social da Gfi Portugal, e, consequentemente, com a própria empresa. This investigation focuses on the dissertation of corporate social responsibility concept, having as a case study a Portuguese IT company - Gfi Portugal. The main goal of the study was the understanding of Gfi Portugal’s stakeholders perception about the comprehensiveness, effectiveness and motivation of the company’s social responsibility. A company is socially responsible when it cumulatively takes actions aimed at integrating social concerns, such as social justice or environmental quality, into its management model, carries out these initiatives on a voluntary basis, guides its business towards sustainable development of society, with particular attention to its stakeholders, and assumes responsibility for its impact. To this extent, the study concluded that Gfi Portugal is a socially responsible company, which has CSR as one of its institutional values. In this study, were interviewed 161 individuals as a representation of Gfi Portugal’s stakeholders. In this sample, employees and some beneficiaries of the CSR initiatives of Gfi Portugal were included. Through the analysis of their answers, it was concluded that Gfi’s social responsibility is perceived as being situated between the average and the good level. In this way, the existing perception is that the initiatives proposed by the company are comprehensive, effective and driven by altruistic and integrative motivations. However, and despite believing the theme is important, even to the point of attributing to the company’s ethical character and to remuneration an equal weight when it comes to choose a job, the employees do not show a real involvement with the social responsibility actions, fact shown by the frankly weak participation rate on these activities. In short, it was observed that, although company's stakeholders recognize the importance of the concept and make a positive assessment of the exercise of social responsibility by the company, there is room for improvement in the communication of the practice to the workers. Thus, it is possible to build a greater engagement between them and Gfi Portugal’s social responsibility, and consequently with the company itself.

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Jhang, Teng-jyun, and 張騰駿. "The use of GFC CO2 analyzer for atmospheric carbon dioxide measurements." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/58828365242914529880.

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碩士 國立中央大學 大氣物理研究所 98 Carbon dioxide is an important greenhouse gas that modifies earth’s radiative balance and climate. Understanding the effects of carbon dioxide for the global climate depend on the technological development and data collection. This paper describes the use of GFC (Gas Filter Correlation) carbon dioxide analyzer for carbon dioxide measurements. GFC carbon dioxide analyzer is main instrument used in the Pacific Greenhouse Gases Measurement (PGGM) program. In order to understand the characteristics, stability and maintenance needs, our lab develops standard processes for the GFC carbon dioxide ana-lyzer installation, operation, instrument calibration, standard carbon dioxide gas calibration, measurement data calibration. The most important part of this paper is to describe and de-velop the standard processes for maintenance in detail, so the maintenance personnel has a good understanding of instrument maintenance. We have conducted extensive in situ mea-surement for carbon dioxide in the campus and an 100-people working office. These results show carbon dioxide concentrations vary with time. Carbon dioxide concentrations showed a diurnal variation with levels lower in daytime than during the night time. The possible causes for these variations could be due to more active convection in the daytime, and the respiration of the plants in nighttime. In indoor 100-people working office, we found carbon dioxide concentrations accu-mulating after 8:00, and could exceed 1000ppm in the afternoon. After getting off duty, the carbon dioxide concentrations reduce to about 450ppm, and carbon dioxide concentrations in the weekend varied smaller than weekday.

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Shih, Jou-Chen, and 施柔臣. "Trade Liberalization and Food Security: A Case Study of Taiwan using Global Food Security Index (GFSI)." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/54fsyf.

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碩士 國立臺灣大學 農業經濟學研究所 103 The effect of trade liberalization (e.g., WTO, FTA, or TPP) on food security has been an important issue in policy debates. An acceptable definition and reasonable measurement of food security is indispensable for such impact assessment. In Taiwan, Korea and Japan where agriculture is traditionally highly protected, the concept of food security is almost equivalent to that of “food self-sufficiency rate”. As a result, trade liberalization with increasing agricultural imports will surely incur negative impacts on domestic agriculture and food security. To deepen the dialogue on food security, we utilized the Global Food Security Index (GFSI) which was created by the Economist Intelligence Unit (EIU) of the Economist in 2012. In contrast to “food self-sufficiency rate”, the GFSI assesses food security across three internationally designated dimensions: affordability, availability and utilization (or quality and safety). As a dynamic quantitative and qualitative benchmarking model, the GFSI was constructed from 28 unique indicators measuring drivers of food security across 109 countries, but without Taiwan. In this study, we have three specific aims to be fulfilled. The first is to calculate the Global Food Security Index (GFSI) for Taiwan and investigate the performance raking of Taiwan in the world. The second is to use the hierarchical data envelopment analysis (DEA) to recalculate the ranking of GFSI, trying to test and verify the weightings assigned are convincible or not. Importantly, the last purpose of this study is to build the time-series data of Taiwan’s GFSI and explore the relationship between Taiwan’s trade liberalization since her WTO accession in 2002 and food security status. The results of this study indicate that the GFSI of Taiwan (74.4 points) took the 24rd place (the top 20%) in the overall ranking among 110 countries in 2014. Each of the three categories ranked 26th, 25th and 27th with 80 points, 68.6 points, and 76.3 points, respectively. Furthermore, the verification results of GFSI by the hierarchical DEA are similar to the original. Using the hierarchical DEA, Taiwan took the 26th place in the overall ranking among 110 countries in 2014 in the first scenario and took the 23rd place in the second scenario instead. The United States still took the first place in the both scenarios, and Singapore which took the fifth place originally became the sixth and second one in the first scenario and second scenario respectively. Adding the theoretical models, we can greatly increase the believability of the GFSI. Although it seems that the food security performance of Taiwan is good according to the GFSI, there are still many aspects that can be improved when we compare with the performance of Singapore, such as GDP per capita and the efficiency of distribution. In this study, the annual GFSIs of Taiwan over the past 15 years were also computed to investigate the association between food security, food self-sufficiency rate, and trade liberalization. Within the past 15 years, there were significantly sharp declines in 2002 and 2008. We inferred that the main reason for the sharp declines in 2002 is the import tariff decrease resulting from Taiwan’s entry into the World Trade Organization (WTO). And for 2008, an economic recession generated by the Global Financial Crisis should be responsible for the significant decline of Taiwan’s GFSI. In general, we found that there has been a steady growth trend of Taiwan’s GFSI since 2002 although food self-sufficiency rate has been declining. In conclusions, judging from the more comprehensive measurement of food security definition, trade liberalization improves the food security status of Taiwan.

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Rödel, Bernd [Verfasser]. "Gfi-1 und Pias3 als Antagonisten bei der Stat3-Signaltransduktion / vorgelegt von Bernd Rödel." 1999. http://d-nb.info/962829455/34.

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Sharpe, Timothy P. "Fiscal and monetary policy in crisis." Thesis, 2014. http://hdl.handle.net/1959.13/1051055.

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Research Doctorate - Doctor of Philosophy (PhD) The Global Financial Crisis and ongoing Eurozone crisis have posed a growing challenge to the implementation of mainstream macroeconomic stabilisation policies. This thesis develops an integrated and coherent theoretical and empirical framework for understanding the constraints on the post-crisis conduct of fiscal and monetary policy among Eurozone and advanced non-Eurozone economies. It is presented as a series of published and submitted research articles which are informed by the principles of Modern Monetary Theory. The central contribution of the thesis is to highlight the policy freedoms of economies which enjoy full fiscal-monetary policy sovereignty. The implications are, first, government within sovereign economies are not adequately exploiting their inherent financial capacity to implement a full employment policy and advance the public purpose. Second, economies which do not enjoy policy sovereignty, such as Eurozone members, face a unique set of institutional constraints which have undermined not only policymakers’ attempts to address the deepening crisis, but the achievement of sustained full employment. The thesis is highly critical of these institutional arrangements and recommends that policy sovereignty is restored since it promotes flexibility in the design and implementation of fiscal and monetary policy, and eliminates the financial constraints vis-à-vis implementing a full employment policy, such as a Job Guarantee.

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Karsunky, Holger [Verfasser]. "Multiple Defekte der Hämatopoese und T-Zellentwicklung in Gfi-1-defizienten Mäusen / vorgelegt von Holger Karsunky." 2000. http://d-nb.info/962762180/34.

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Kuo, Yuan-Yeh, and 郭遠燁. "The Transcriptional Repression Function and RNA Stability Control of Growth Factor Independence-1B (Gfi-1B) in Hematopoietic Cells." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/24026318779455267750.

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博士 國立臺灣大學 生物化學暨分子生物學研究所 95 Gfi-1B (growth factor independence-1B) gene is a Gfi-family transcriptional repressor, whose expression plays an essential role in erythropoiesis. Early erythroid progenitor cells overexpressing Gfi-1Bexhibit massive apoptosis after 7-10 days of culture with a significant reduction of Bcl-xL expression. Therefore, the aim of this study is to uncover the role of Gfi-1B in the regulation of Bcl-xL transcription GATA-1 is also an essential transcriptional factor in erythropoiesis. Our laboratory previously showed that Gfi-1B interacts with GATA-1. Using ChIP assays, I provide evidence that GATA-1 binds to the Bcl-x promoter constantly in the entire induction period, while Gfi-1B is transiently associated with the promoter in the early phase. GATA-1 binds to the noncanonical GATT motif of the Bcl-x promoter for trans-activation, and that enforced expression of Gfi-1B represses the Bcl-x promoter in a GATA-1-dependent manner. Gfi-1B expressed at increased levels is recruited to the Bcl-x promoter through its association with GATA-1, suppressing Bcl-xL transcription. Furthermore, I showed that imatonob, Bcr-Abl kinase inhibitor, causes up-regulation of Gfi-1B in K562 cells, where it also cooperated with GATA-1 to repress Bcl-xL transcription. Gfi-1B knockdown by RNA interference diminished imatinib-induced apoptosis, while the overexpression of Gfi-1B sensitized K562 cells to arsenic-induced death. These findings illuminate the role of Gfi-1B in GATA-1-mediated transcription in the survival aspect of erythroid cells. In addition, the post-transcriptional control of the Gfi-1B gene is studied. It was found that Gfi-1B mRNA is a short half-life transcript containing a destabilizing element within the coding region of the Gfi-1B mRNA. I further defined the region of the Gfi-1B coding region determinant (CRD) and demonstrated that this CRD confers cis-directed destabilization coupled with translation.

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Kuo, Yuan-Yeh. "The Transcriptional Repression Function and RNA Stability Control of Growth Factor Independence-1B (Gfi-1B) in Hematopoietic Cells." 2007. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-1407200722271800.

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Teixeira, Maria Alexandra Mesquita. "Fraude alimentar versus defesa dos alimentos e medidas de mitigação : de acordo com os referenciais de gestão da segurança e qualidade alimentar GFSI." Master's thesis, 2018. http://hdl.handle.net/10400.14/30651.

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A produção de alimentos encontra-se atualmente globalizada, o que torna os alimentos um veículo fácil para causar danos à saúde dos consumidores, existindo, portanto, a necessidade dos governos e empresas do setor alimentar implementarem medidas de defesa dos alimentos. Simultaneamente, a extensão e complexidade da cadeia de fornecimento de alimentos, aliada à pressão económica propicia a disposição para a fraude alimentar. O estágio curricular na empresa BioConnection - Consultoria e Formação, Lda, teve como um dos objetivos a análise da perceção e posição das empresas da cadeia de fornecimento alimentar nacionais face à defesa dos alimentos e à fraude alimentar, averiguando as medidas de controlo que já se encontram implementadas e a sua relação com a adoção de normas de certificação. A recolha de dados passou pelo envio de um inquérito a empresas do setor alimentar, tendo uma taxa de resposta de 34,3%. A definição correta de “defesa dos alimentos” foi selecionada por 89,0% das empresas certificadas e 53,3% das empresas não certificadas. A definição correta de “fraude alimentar” foi selecionada por 97,3% das empresas certificadas e 86,7% das empresas não certificadas. O plano de defesa dos alimentos e fraude alimentar estava implementado em 83,6% e 74,0%, respetivamente, das empresas certificadas e em 30,0% e 20,0%, respetivamente, das empresas não certificadas. A formação aos colaboradores em defesa dos alimentos e fraude alimentar fazia parte do plano de formação de 90,4% e 72,6%, respetivamente, das empresas certificadas e em 53,3% e 33,3%, respetivamente, das empresas não certificadas. Relativamente ao nível de risco para a defesa dos alimentos e fraude alimentar, observou-se uma associação significativa na atribuição dos dois níveis de risco (R = 0,467; p < 0,001). O nível de risco de fraude alimentar atribuído demonstrou ser influenciado pelo setor de atividade da empresa (p = 0,098), sendo que os setores apontados como de maior risco foram: agricultura, produção animal, caça e atividades dos serviços relacionados, abate de animais, preparação e conservação de carne e de produtos à base de carne; produção de óleos e gorduras animais e vegetais; indústria de laticínios; e comércio por grosso de produtos alimentares, bebidas e tabaco. Neste estudo verificou-se que a preocupação com estes dois temas é mais evidente em empresas certificadas, mas que a formação aos colaboradores é transversal, sendo necessário um maior investimento nas medidas de prevenção nas empresas não certificadas. Food production is currently globalized, which makes food an easy vehicle to cause harm to consumers health, so there is a need for governments and food companies to implement food defense measures. Simultaneously, the extension and complexity of the food supply chain, allied with the economic pressure facilitates the tendency for food fraud. The main objective of the curricular internship at BioConnection - Consultoria e Formação, Lda was to analyse the perception and position of the national food supply chain companies in regarding to food defense and food fraud, verifying the control measures that are already implemented and their relationship with the adoption of certification standards.Data were collected by sending a questionnaire to food companies, with a rate response of 34.3%. The correct definition of "food defense" was selected by 89.0% of certified companies and 53.3% of non-certified companies. The correct definition of "food fraud" was selected by 97.3% of certified companies and 86.7% of non-certified companies. The food defense and food fraud plan was implemented in 83.6% and 74.0%, respectively, of the certified companies and 30.0% and 20.0%, respectively, of the non-certified companies. The training of employees in food defense and food fraud was part of the training plan in 90.4% and 72.6%, respectively, of the certified companies and in 53.3% and 33.3%, respectively, of the non-certified companies. Regarding the level of risk for food defense and food fraud, it was found a significative association in the assignment of the two risk levels (R = 0.467; p <0.001). The risk level of food fraud attributed was influenced by the company activity sector (p = 0.098), and the sectors considered to be at greatest risk were: agriculture, animal production, hunting and related service activities, slaughter of animals, preparation and preservation of meat and meat products; production of animal and vegetable oils and fats; dairy industry; and wholesale of food, beverages and tobacco. In this study it was verified that the concern with these two themes is more evident in certified companies, but employees training is transversal, being necessary a greater investment in the prevention measures in the non-certified companies.

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SU-CHU, CHOU, and 周素珠. "A Study on The Establishment New DEFSOP Model of Control Inspection Mechanisms for Comparison Analysis of ISO22000, TQF and GFSI for Food Safety Management System." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/w3pv9w.

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碩士 國立宜蘭大學 多媒體網路通訊數位學習碩士在職專班 105 Recent food safety incidents in our country due to heavy penalties not caused Controls failed, verify that the food safety management standard, ISO 22000 international standard is effective food security control system, through the circulation mechanism and rigorous documentation requirements, allowing control better control regime. Ministry of Economic Affairs in 104 years September 23, repealed "Food GMP implementation of the program," the restructuring of non-governmental organizations - Taiwan Association for Food excellent (TQF), included consumer protection, access groups, and resorted to track and trace, to strengthen audit, access to international organizational identification and other measures. TQF to be similar products are certified counts, subject to raw material traceability, strengthen inspection and import the United States, Australia, Japan and Korea are in the "Global Food Safety Initiative (GFSI)" with a food safety management system, expect Taiwan TQF industry can reach international Level. European food retailers put forward "Global Food Safety Initiative (Global Food Safety Initiative, GFSI)" in 2000, its primary purpose is to strengthen global food security, enhance consumer confidence and to establish food safety plans, and by providing a platform for knowledge exchange and through food retailers, the participation of suppliers, manufacturers and recognition, certification bodies, to discuss food safety issues, to achieve consistent and objective compliance standards and reduce unnecessary duplication of validation evaluation. 105, adopted in June TQF verify production lines totaling 257, have been as high as 4,402 items validated products; expected to end 105 years TQF will complete GFSI Global Food Safety Initiative differences than using certification standards of the world and thus, the establishment of Taiwan's food network security, more competitive in the export. Food competent authority is the Ministry of Health and Welfare Executive Yuan set up the White Paper on food safety, farm management and integration of the table, the source of the Construction Control of logistics, import management throughout the production, transformation and development of mechanisms to monitor the flow of risk to predict the ability of five goals. In this study, ISO22000 and TQF comparative analysis to explore the lack of food safety management, the import and ISO22000 authentication. Aggregated verify food safety management, food safety net six goals Controls and food safety and health management method, and reference scholar Professor Lin Yilong proposed four stages DEFSOP Model of the core, the construction of core indicators of food safety controls and auditing Mechanism. Food Safety Network Control where six goals, including ingredients and health, health information technology, information transparency, transparency of the inspection, inspectors specialized, professional verification of, six policies must go hand in hand, a comprehensive strategy and measures to resolve food security crisis, the people eat at ease. Supplemented by laboratory (ISO 17025), standard operating procedures (ISO 22000), inspection and audit personnel (ISO 17024 ) as the core, introducing demand side, the supply side, environmental surfaces, carry out PDCA cycle of continuous improvement. In sampling inspection unit, civil audit, government control, three-line duties, and the implementation of food distribution footprint management.

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42

Kaczynski, Adam. "A post-Keynesian stock-flow consistent model of the Global Financial Crisis and the age of secular stagnation." Thesis, 2020. http://hdl.handle.net/1959.13/1421137.

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Research Doctorate - Doctor of Philosophy (PhD) This thesis is an attempt to build a dynamic, long run, Stock-Flow Consistent, Post Keynesian model of the Global Financial Crisis and Secular Stagnation. While multiple New Keynesian Dynamic Stochastic General Equilibrium models of these historic phenomena already exist, these models are built on theoretical foundations which have been rejected by Post Keynesians because of their inadequacy. The Sraffian Supermultiplier has been chosen as the theoretical framework, isolating parts of the economy generating instability from the parts which may set the trend in the long run. The model uses a continuous-time framework and is expressed as a differential-algebraic system of equations. It is simulated using an Open Source package OpenModelica which is widely used in empirical and technical sciences for simulating dynamic systems. While not calibrated by regression, and more theoretical than econometric, it nevertheless reproduces multiple macroeconomic phenomena and stylised facts which have puzzled mainstream economists. This research is an attempt to advance the macroeconomic modelling methodology and contribute to understanding macroeconomic processes by demonstrating how complex phenomena can emerge when simple parts of the economy interact. The understanding is based on sound macroeconomic theories built by Marx, Keynes, Kalecki, Sraffa and contemporary Post Keynesian economists.

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Mota, Ana Alexandra Ribeiro da. "Implementação de requisitos da Norma Gfsi British Retail Consortium Global Standard For Food Safety V. 7 numa empresa de importação, embalamento, armazenamento e distribuição de especiarias, ervas aromáticas e outros produtos." Master's thesis, 2018. http://hdl.handle.net/10400.14/30594.

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O esforço contínuo que tem sido desenvolvido pelos intervenientes envolvidos nas diferentes etapas da cadeia alimentar no sentido de garantir a segurança e a qualidade dos géneros alimentícios comercializados resultou num avanço das boas práticas de fabrico e de higiene que, consequentemente, melhoram as condições do produto final. Esses pré-requisitos que constituem, em geral, o Plano HACCP, têm sido melhorados e têm originado requisitos de normas que têm como objetivo a sua implementação por empresas da área alimentar para que estas desenvolvam sistemas de gestão da qualidade e segurança alimentar que são reconhecidos mundialmente pelo seu rigor. Foi neste contexto de aplicação de alguns requisitos da versão sete do referencial de segurança alimentar, BRC Global Standard for Food Safety, numa empresa de embalamento de especiarias, ervas aromáticas e outros produtos designada por Navires – Sociedade Nacional de Víveres, Lda. que este estágio foi realizado. O principal objetivo do trabalho foi desenvolver metodologias, baseadas nas avaliações de risco já efetuadas, que fossem, posteriormente, implementadas pelos responsáveis dos processos realizados na empresa de forma a dar cumprimento aos requisitos da norma associados aos mesmos. Todavia, também foram desempenhadas outras tarefas não relacionadas diretamente com o referencial em questão mas que estão associadas ao sistema de gestão da qualidade já implementado e certificado na empresa, pela NP EN ISO 9001. The continuous effort that has been developed by the stakeholders involved in different stages of the food chain to ensure the safety and quality of marketed foodstuffs has resulted in an improvement in good manufacturing and hygiene practices which, consequently, improve the conditions of the final product. These prerequisites, which generally constitute the HACCP Plan, have been improved and have given rise to standards requirements aimed at their implementation by food companies to develop food quality and safety management systems that are recognized worldwide for its thoroughness. It was in this context of application of some requirements of version seven of a food safety reference, BRC Global Standard for Food Safety, in a packaging company of spices, herbs and other products designated by Navires - Sociedade Nacional de Víveres, Lda. that this internship has been completed. The main objective of the work was to develop methodologies, based on the risk assessments already carried out, that were later implemented by those responsible for the processes performed in the company in order to comply with the requirements of the standard associated with them. However, other tasks not directly related to the referential in question, have also been performed but are associated with the quality management system already implemented and certified in the company, by NP EN ISO 9001.

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44

(9780605), Md Khokan Bepari. "Value relevance of accounting information during a financial crisis: An empirical analysis of Australian companies." Thesis, 2012. https://figshare.com/articles/thesis/Value_relevance_of_accounting_information_during_a_financial_crisis_An_empirical_analysis_of_Australian_companies/13465460.

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"This thesis extends value relevance research by examining the changes in the value relevance of fundamental accounting measures in the unique context of a global financial crisis (GFC). This thesis examines the impact of the 2008-2009 GFC on the value relevance of book value of equity, earnings and cash flow from operations (CFO). It also examines the impact of the GFC on the value relevance of tangible assets, intangible assets and goodwill. ... This thesis is positioned into the CMR in Accounting. Positivist epistemology and objective ontology underpin the philosophical backgrounds of this thesis"--Abstract.

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45

Bharath, R. "Regionalization Of Hydrometeorological Variables In India Using Cluster Analysis." Thesis, 2014. https://etd.iisc.ac.in/handle/2005/2643.

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Regionalization of hydrometeorological variables such as rainfall and temperature is necessary for various applications related to water resources planning and management. Sampling variability and randomness associated with the variables, as well as non-availability and paucity of data pose a challenge in modelling the variables. This challenge can be addressed by using stochastic models that utilize information from hydrometeorologically similar locations for modelling the variables. A set of locations that are hydrometeorologically similar are referred to as homogeneous region or pooling group and the process of identifying a homogeneous region is referred to as regionalization. The thesis concerns development of new approaches to regionalization of (i) extreme rainfall,(ii) maximum and minimum temperatures, and (iii) rainfall together with maximum and minimum temperatures. Regionalization of extreme rainfall and frequency analysis based on resulting regions yields quantile estimates that find use in design of water control (e.g., barrages, dams, levees) and conveyance structures (e.g., culverts, storm sewers, spillways) to mitigate damages that are likely due to floods triggered by extreme rainfall, and land-use planning and management. Regionalization based on both rainfall and temperature yield regions that could be used to address a wide spectrum of problems such as meteorological drought analysis, agricultural planning to cope with water shortages during droughts, downscaling of precipitation and temperature. Conventional approaches to regionalization of extreme rainfall are based extensively on statistics derived from extreme rainfall. Therefore delineated regions are susceptible to sampling variability and randomness associated with extreme rainfall records, which is undesirable. To address this, the idea of forming regions by considering attributes for regionalization as seasonality measure and site location indicators (which could be determined even for ungauged locations) is explored. For regionalization, Global Fuzzy c-means (GFCM) cluster analysis based methodology is developed in L-moment framework. The methodology is used to arrive at a set of 25 homogeneous extreme rainfall regions over India considering gridded rainfall records at daily scale, as there is dearth of regionalization studies on extreme rainfall in India Results are compared with those based on commonly used region of influence (ROI) approach that forms site-specific regions for quantile estimation, but lacks ability to delineate a geographical area into a reasonable number of homogeneous regions. Gridded data constitute spatially averaged rainfall that might originate from a different process (more synoptic) than point rainfall (more convective). Therefore to investigate utility of the developed GFCM methodology in arriving at meaningful regions when applied to point rainfall data, the methodology is applied to daily rainfall records available for 1032 gauges in Karnataka state of India. The application yielded 22 homogeneous extreme rainfall regions. Experiments carried out to examine utility of GFCM and ROI based regions in arriving at quantile estimates for ungauged sites in the study area reveal that performance of GFCM methodology is fairly close to that of ROI approach. Errors were marginally lower in the case of GFCM approach in analysis with observed point rainfall data over Karnataka, while its converse was noted in the case of analysis with gridded rainfall data over India. Neither of the approaches (CA, ROI) was found to be consistent in yielding least error in quantile estimates over all the sites. The existing approaches to regionalization of temperature are based on temperature time series or their related statistics, rather than attributes effecting temperature in the study area. Therefore independent validation of the delineated regions for homogeneity in temperature is not possible. Another drawback of the existing approaches is that they require adequate number of sites with contemporaneous temperature records for regionalization, because the delineated regions are susceptible to sampling variability and randomness associated with the temperature records that are often (i) short in length, (ii) limited over contemporaneous time period and (iii) spatially sparse. To address these issues, a two-stage clustering approach is developed to arrive at regions that are homogeneous in terms of both monthly maximum and minimum temperatures ( and ). First-stage of the approach involves (i) identifying a common set of possible predictors (LSAVs) influencing and over the entire study area, and (ii) using correlations of those predictors with and along with location indicators (latitude, longitude and altitude) as the basis to delineate sites in the study area into hard clusters through global k-means clustering algorithm. The second stage involves (i) identifying appropriate LSAVs corresponding to each of the first-stage clusters, which could be considered as potential predictors, and (ii) using the potential predictors along with location indicators (latitude, longitude and altitude) as the basis to partition each of the first-stage clusters into homogeneous temperature regions through global fuzzy c-means clustering algorithm. A set of 28 homogeneous temperature regions was delineated over India using the proposed approach. Those regions are shown to be effective when compared to an existing set of 6 temperature regions over India for which inter-site cross-correlations were found to be weak and negative for several months, which is undesirable. Effectiveness of the newly formed regions is demonstrated. Utility of the proposed maxTminT homogeneous temperature regions in arriving at PET estimates for ungauged locations within the study area was demonstrated. The estimates were found to be better when compared to those based on the existing regions. The existing approaches to regionalization of hydrometeorological variables are based on principal components (PCs)/ statistics/indices determined from time-series of those variables at monthly and seasonal scale. An issue with use of PCs for regionalization is that they have to be extracted from contemporaneous records of hydrometeorological variables. Therefore delineated regions may not be effective when the available records are limited over contemporaneous time period. A drawback associated with the use of statistics/indices is that they (i) may not be meaningful when data exhibit nonstationarity and (ii) do not encompass complete information in the original time series. Consequently the resulting regions may not be effective for the desired purpose. To address these issues, a new approach is proposed. It considers information extracted from wavelet transformations of the observed multivariate hydrometeorological time series as the basis for regionalization by global fuzzy c-means clustering procedure. The approach can account for dynamic variability in the time series and its nonstationarity (if any). Effectiveness of the proposed approach in forming homogeneous hydrometeorological regions is demonstrated by application to India, as there are no prior attempts to form such regions over the country. The investigations resulted in identification of 29 regions over India, which are found to be effective and meaningful. Drought Severity-Area-Frequency (SAF) curves are developed for each of the newly formed regions considering the drought index to be Standardized Precipitation Evapotranspiration Index (SPEI).

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46

Bharath, R. "Regionalization Of Hydrometeorological Variables In India Using Cluster Analysis." Thesis, 2014. http://etd.iisc.ernet.in/handle/2005/2643.

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Regionalization of hydrometeorological variables such as rainfall and temperature is necessary for various applications related to water resources planning and management. Sampling variability and randomness associated with the variables, as well as non-availability and paucity of data pose a challenge in modelling the variables. This challenge can be addressed by using stochastic models that utilize information from hydrometeorologically similar locations for modelling the variables. A set of locations that are hydrometeorologically similar are referred to as homogeneous region or pooling group and the process of identifying a homogeneous region is referred to as regionalization. The thesis concerns development of new approaches to regionalization of (i) extreme rainfall,(ii) maximum and minimum temperatures, and (iii) rainfall together with maximum and minimum temperatures. Regionalization of extreme rainfall and frequency analysis based on resulting regions yields quantile estimates that find use in design of water control (e.g., barrages, dams, levees) and conveyance structures (e.g., culverts, storm sewers, spillways) to mitigate damages that are likely due to floods triggered by extreme rainfall, and land-use planning and management. Regionalization based on both rainfall and temperature yield regions that could be used to address a wide spectrum of problems such as meteorological drought analysis, agricultural planning to cope with water shortages during droughts, downscaling of precipitation and temperature. Conventional approaches to regionalization of extreme rainfall are based extensively on statistics derived from extreme rainfall. Therefore delineated regions are susceptible to sampling variability and randomness associated with extreme rainfall records, which is undesirable. To address this, the idea of forming regions by considering attributes for regionalization as seasonality measure and site location indicators (which could be determined even for ungauged locations) is explored. For regionalization, Global Fuzzy c-means (GFCM) cluster analysis based methodology is developed in L-moment framework. The methodology is used to arrive at a set of 25 homogeneous extreme rainfall regions over India considering gridded rainfall records at daily scale, as there is dearth of regionalization studies on extreme rainfall in India Results are compared with those based on commonly used region of influence (ROI) approach that forms site-specific regions for quantile estimation, but lacks ability to delineate a geographical area into a reasonable number of homogeneous regions. Gridded data constitute spatially averaged rainfall that might originate from a different process (more synoptic) than point rainfall (more convective). Therefore to investigate utility of the developed GFCM methodology in arriving at meaningful regions when applied to point rainfall data, the methodology is applied to daily rainfall records available for 1032 gauges in Karnataka state of India. The application yielded 22 homogeneous extreme rainfall regions. Experiments carried out to examine utility of GFCM and ROI based regions in arriving at quantile estimates for ungauged sites in the study area reveal that performance of GFCM methodology is fairly close to that of ROI approach. Errors were marginally lower in the case of GFCM approach in analysis with observed point rainfall data over Karnataka, while its converse was noted in the case of analysis with gridded rainfall data over India. Neither of the approaches (CA, ROI) was found to be consistent in yielding least error in quantile estimates over all the sites. The existing approaches to regionalization of temperature are based on temperature time series or their related statistics, rather than attributes effecting temperature in the study area. Therefore independent validation of the delineated regions for homogeneity in temperature is not possible. Another drawback of the existing approaches is that they require adequate number of sites with contemporaneous temperature records for regionalization, because the delineated regions are susceptible to sampling variability and randomness associated with the temperature records that are often (i) short in length, (ii) limited over contemporaneous time period and (iii) spatially sparse. To address these issues, a two-stage clustering approach is developed to arrive at regions that are homogeneous in terms of both monthly maximum and minimum temperatures ( and ). First-stage of the approach involves (i) identifying a common set of possible predictors (LSAVs) influencing and over the entire study area, and (ii) using correlations of those predictors with and along with location indicators (latitude, longitude and altitude) as the basis to delineate sites in the study area into hard clusters through global k-means clustering algorithm. The second stage involves (i) identifying appropriate LSAVs corresponding to each of the first-stage clusters, which could be considered as potential predictors, and (ii) using the potential predictors along with location indicators (latitude, longitude and altitude) as the basis to partition each of the first-stage clusters into homogeneous temperature regions through global fuzzy c-means clustering algorithm. A set of 28 homogeneous temperature regions was delineated over India using the proposed approach. Those regions are shown to be effective when compared to an existing set of 6 temperature regions over India for which inter-site cross-correlations were found to be weak and negative for several months, which is undesirable. Effectiveness of the newly formed regions is demonstrated. Utility of the proposed maxTminT homogeneous temperature regions in arriving at PET estimates for ungauged locations within the study area was demonstrated. The estimates were found to be better when compared to those based on the existing regions. The existing approaches to regionalization of hydrometeorological variables are based on principal components (PCs)/ statistics/indices determined from time-series of those variables at monthly and seasonal scale. An issue with use of PCs for regionalization is that they have to be extracted from contemporaneous records of hydrometeorological variables. Therefore delineated regions may not be effective when the available records are limited over contemporaneous time period. A drawback associated with the use of statistics/indices is that they (i) may not be meaningful when data exhibit nonstationarity and (ii) do not encompass complete information in the original time series. Consequently the resulting regions may not be effective for the desired purpose. To address these issues, a new approach is proposed. It considers information extracted from wavelet transformations of the observed multivariate hydrometeorological time series as the basis for regionalization by global fuzzy c-means clustering procedure. The approach can account for dynamic variability in the time series and its nonstationarity (if any). Effectiveness of the proposed approach in forming homogeneous hydrometeorological regions is demonstrated by application to India, as there are no prior attempts to form such regions over the country. The investigations resulted in identification of 29 regions over India, which are found to be effective and meaningful. Drought Severity-Area-Frequency (SAF) curves are developed for each of the newly formed regions considering the drought index to be Standardized Precipitation Evapotranspiration Index (SPEI).

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Sukkar, Atif Abdullah. "Political reform and its impacts on political stability: a case study of the Kingdom of Saudi Arabia during the period from 1990 to 2010." Thesis, 2010. https://vuir.vu.edu.au/17748/.

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This research investigates the process of political reform in Saudi Arabia. Central to the study is an examination of the Kingdom of Saudi Arabia‘s constitutional reforms implemented between 1990 and 2010, focusing on the Consultative Council (Majlis al-shūrā) and municipal councils as case studies. The research analyses the objectives, values and concerns that have informed the Kingdom‘s policies of political reform. Also, the study examines the extent to which Saudi Government reforms have responded to internal and external pressures for more far reaching reform and democratization. The study investigates how the events of the 1990-1991 Gulf War, the 9/11 attacks on the World Trade Center and the Global Financial Crisis have influenced the direction of the Saudi Government‘s political reforms. Furthermore, the study examines how the Saudi Government dealt with various key stakeholders, co-opting some and excluding others from the reform process.

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Veloso, Marta Ribeiro de Araújo Cardoso. "Relatório detalhado sobre a atividade profissional desenvolvida no perído 2007-2015 no Gabinete de Fundos Comunitários do Município da Póvoa de Lanhoso." Master's thesis, 2015. http://hdl.handle.net/1822/40734.

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Dissertação de mestrado em Geografia (área de especialização em Planeamento e Gestão do Território) O presente relatório enquadra-se no processo de obtenção do grau de mestre em Geografia pela Universidade do Minho, especialização em Planeamento e Gestão do Território, através do reconhecimento da experiência profissional da candidatada no Gabinete de Fundos Comunitários do Município da Póvoa de Lanhoso. Inicia-se com a apresentação do percurso profissional da candidata e enquadramento do mesmo, elencando e descrevendo, por ordem cronológica, os trabalhos realizados ao longo do período temporal em análise (2007-2015). De seguida procede-se a uma reflexão crítica em torno da experiência profissional desenvolvida no período temporal definido, destacando duas temáticas: o processo de planeamento que antecede os períodos de programação e o impacte dos Fundos Europeus Estruturais e de Investimento no concelho da Póvoa de Lanhoso, fazendo referência concreta aos investimentos no domínio da educação. Por fim e antes das notas conclusivas, procura-se explicitar o modo como a experiência profissional da candidata contribuiu para o desenvolvimento e / ou reforço de competências na área científica do mestrado, que se organizam em torno de dois grandes domínios de atuação. Por um lado, competências desenvolvidas ao nível da participação, conceção, implementação e acompanhamento/ avaliação de planos de cariz estratégico. Por outro lado, competências desenvolvidas ao nível da elaboração de projetos de desenvolvimento local no âmbito de candidaturas aos Fundos Europeus Estruturais e de Desenvolvimento. The present report frames itself on attainment to the master degree in Geography by the University of Minho, with specialization on Territorial Management and Planning, through the recognition of the candidate's professional experience on the Communitarian Funds Office of Póvoa de Lanhoso's Municipality. It begins with the presentation of the candidate’s professional career and by framing, listing and describing chronologically the works carried out over the period of time under review (2007- 2015). After that we proceed to a critical reflection on the experience developed within the given time period, highlighting two main themes: the planning process that precedes programming periods and the impact of the European Structural and Investments Funds in Póvoa do Lanhoso’s County, specifically referring the investment on education. Finally, and before the concluding remarks, we try to explain how the candidate’s professional experience has contributed to the development and/or reinforcement of skills on the master course’s scientific area, which are organized around two main domains. On the one hand there are the skills developed through participation, planning, implementation and monitoring / evaluation of strategic-oriented plans. On the other hand, there are the skills developed preparing local development projects within the scope of applications for the European Structural and Development Funds.

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Erasmus, Coert Frederik. "Determinants of asset quality in South African banks." Thesis, 2018. http://hdl.handle.net/10500/25138.

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The maturity transformation of deposits is a primary driver of economic growth, as loans enable borrowers to spend funds, thereby growing the economy. However, if borrowers cannot repay their loans, the asset quality of banks deteriorate, resulting in non-performing loans or, worse, an economic crisis. An understanding of how macroeconomic and microeconomic determinants impact bank asset quality in South Africa can contribute to knowledge of the bank asset quality phenomenon in the African context. Due to the 2008/2009 global financial crisis, the introduction of new legislation and the value of gold exports, the South African economy presents an opportunity to make an original contribution to the knowledge of determinants that influence bank asset quality. In addition to studying bank asset quality determinants that are contested in research, this study also aims to determine whether a superior returns determinant of non-performing loans exists when comparing a bank’s profitability determinants, namely return on assets, return on equity and interest income on loans. This study applied panel data regression analysis, making use of a balanced panel approach, to study the determinants of bank asset quality. This approach recontextualises the existing bank asset quality theory for the South African financial sector. The results indicate that South Africa is not resilient against the impact of global financial crises trickling through international trade linkages and that regulatory changes do not instantly improve bank asset quality, and may even reduce the short-term asset quality. Moreover, bank asset quality in South Africa is sensitive to the total value of gold exports. It is evident from the profitability measures that the interest income on loans is the most suitable profitability measure of bank asset quality. This study provides an original contribution to bank asset quality determinants and recommends that regulators should pre-emptively determine the impact of new legislation on bank asset quality. Furthermore, interest income on loans as a profitability measure provides the most accurate results. Lastly, a single-country bank asset quality analysis is important, especially for economies that have commodity exports that significantly weigh in on the bank asset mix. Die termyntransformasie rakende deposito's is die primêre dryfkrag vir groei in die ekonomie: Lenings maak dit vir leners moontlik om fondse te bestee, wat die ekonomie laat groei. Indien hierdie leners hul lenings egter nie kan terugbetaal nie, gaan die gehalte van bankbates agteruit, wat tot wanpresterende lenings of, nog erger, tot 'n ekonomiese krisis kan lei. As begryp kan word hoe makro-ekonomiese en mikro-ekonomiese bepalende faktore op die gehalte van bankbates in Suid-Afrika inwerk, kan dit bydra tot kennis van die verskynsel van bankbategehalte in die Afrika-konteks. In die lig van die 2008/2009 wêreldwye finansiële krisis, die uitvaardiging van nuwe wetgewing en die waarde van gouduitvoere bied die Suid-Afrikaanse ekonomie ’n geleentheid om ’n oorspronklike bydrae te lewer tot kennis van die bepalende faktore wat bankbategehalte beïnvloed. Benewens die bestudering van die bepalende faktore van die gehalte van bankbates wat in navorsing redelik omstrede is, het hierdie studie ten doel om, wanneer 'n bank se winsgewendheidsbepalers, naamlik opbrengs op bates, opbrengs op ekwiteit (eiekapitaal) en rente-inkomste op lenings, met mekaar vergelyk word, vas te stel of daar ’n superieure opbrengsbepaler van wanpresterende lenings bestaan. Vir hierdie studie is ’n regressieontleding van paneeldata uitgevoer, en daar is van ’n gebalanseerde paneelbenadering gebruik gemaak om die bepalende faktore van bankbategehalte te bestudeer. Hierdie benadering herkontekstualiseer die bestaande bankbategehalteteorie vir die Suid-Afrikaanse finansiële sektor. Die resultate van die studie dui daarop dat Suid-Afrika nie veerkragtig is om die uitwerking van wêreldwye finansiële krisisse teen te werk wat met internasionale handelskakelings deursyfer nie en dat reguleringsveranderinge nie dadelik die bankbategehalte verbeter nie; dit kan inteendeel die korttermynbategehalte verlaag. Bowendien is die bankbategehalte in Suid-Afrika gevoelig vir die totale waarde van gouduitvoere. Dit blyk uit die winsgewendheidsmaatstawwe dat die rente-inkomste op lenings die mees geskikte winsgewendheidsmaatstaf van bankbategehalte is. Hierdie studie lewer ’n oorspronklike bydrae tot die bepalers van bankbategehalte en beveel aan dat reguleerders vooruit reeds die uitwerking van nuwe wetgewing op bankbategehalte moet bepaal. Daarby voorsien rente-inkomste op lenings as winsgewendheidsmaatstaf die akkuraatste resultate. Laastens is ’n ontleding van ’n enkele land se bankbategehalte van belang, in die besonder vir ekonomieë met kommoditeitsuitvoere wat beduidend tot die samestelling van bankbates bydra. Kadimo ya nako ye kopana ya ditipositi ke mokgwa wo bohlokwa wa kgolo ya ekonomi, ka ge dikadimo di dumelela baadimi go šomiša matlotlo, go realo e le go godiša ekonomi. Efela, ge baadimi ba sa kgone go lefela dikadimo tša bona, boleng bja thoto ya dipanka bo a phuhlama, go feleletša go e ba le dikadimo tše di sa šomego gabotse goba, go feta fao, phuhlamo ya ekonomi. Kwešišo ya ka fao ditaetšo tša makroekonomi le maekroekonomi di huetšago boleng bja thoto ya panka ka Afrika Borwa e ka ba le seabe go tsebo ya taba ya boleng bja thoto ya panka go ya ka seemo sa Afrika. Ka lebaka la mathata a ditšhelete a lefase a 2008/2009, tsebišo ya molao wo moswa le boleng bja dithomelontle tša gauta, ekonomi ya Afrika Borwa e fa sebaka seabe sa mathomo tsebong ya ditaetšo tšeo di huetšago boleng bja thoto ya panka. Go tlaleletša nyakišišong ya ditaetšo tša boleng bja thoto ya panka tšeo di ganetšwago nyakišišong, maikemišetšo a nyakišišo ye gape ke go laetša ge eba taetšo ya letseno le legolo la dikadimo tše di sa šomego gabotse di gona ge go bapetšwa ditaetšo tša poelo ya panka, e lego letseno la dithoto, letseno la dišere le letseno la dikadimo. Nyakišišo ye e šomišitše tshekatsheko ya poelomorago ya datha ya phanele, ya go šomiša mokgwa wa phanele wo o lekaneditšwego, go nyakišiša ditaetšo tša boleng bja thoto ya panka. Mokgwa wa go tšwetšapele gape teori ya boleng bja thoto ya panka ya lekala la Afrika Borwa la ditšhelete. Dipoelo di laetša gore Afrika Borwa ga e fokole kgahlanong le khuetšo ya mathata a ditšhelete a lefase ao a rothelago ka dikamanong tša kgwebišano ya boditšhabatšhaba le gore diphetogo tša taolo ga di kaonafatše boleng bja thoto ya panka ka lebelo, gomme di ka fokotša le boleng bja thoto bja paka ye kopana. Go feta fao, boleng bja thoto ya panka ka Afrika Borwa bo ela hloko boleng bja palomoka bja dithomelontle tša gauta. Go a bonagala go tšwa go dikgato tša tiro ya poelo gore letseno la tswala godimo ga dikadimo ke kgato ya poelo ye maleba gagolo ya boleng bja thoto ya panka. Nyakišišo ye e fa seabe sa mathomo ditaetšo tša boleng bja thoto ya panka gomme e šišinya gore balaodi ba swanela go laetša e sa le ka pela khuetšo ya molao wo moswa ka ga boleng bja thoto ya panka. Go feta fao, letseno la tswala godimo ga dikadimo bjalo ka kelo ya tiro ya poelo le go fa dipoelo tše di lebanego gabotse. Sa mafelelo, tshekatsheko ya boleng bja thoto ya panka ya naga e tee, kudu diekonomi tšeo di nago le dithomelontle tša ditšweletšwa tšeo gagolo di dumelelago motswako wa thoto ya panka. Business Management Ph. D. (Management Studies)

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Dissertations / Theses on the topic 'GFCI'

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