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1

&NA;. "Managing GI bleeding." Inpharma Weekly &NA;, no. 906 (1993): 18. http://dx.doi.org/10.2165/00128413-199309060-00034.

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&NA;. "Upper GI bleeding." Inpharma Weekly &NA;, no. 825 (1992): 4. http://dx.doi.org/10.2165/00128413-199208250-00007.

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3

Wong, Richard C. K. "Acute GI Bleeding." Gastrointestinal Endoscopy 58, no. 3 (2003): 409–12. http://dx.doi.org/10.1067/s0016-5107(03)00015-4.

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4

Hurlstone, DP, and AJ Lobo. "Upper GI bleeding." Foundation Years 1, no. 2 (2005): 28–32. http://dx.doi.org/10.1053/s1744-1889(06)70018-4.

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5

Gralnek, Ian M. "Upper GI Bleeding." Gastroenterology Clinics of North America 43, no. 4 (2014): xv—xvi. http://dx.doi.org/10.1016/j.gtc.2014.09.001.

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6

Falk, Gary W. "Upper GI Bleeding." Gastroenterology Clinics of North America 43, no. 4 (2014): xiii. http://dx.doi.org/10.1016/j.gtc.2014.09.002.

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7

ÖCAL, Serkan, and Mehmet Mutlu ÇATLI. "Lower Gastrointestinal Bleeding." Journal of Experimental and Clinical Medicine 38, SI-1 (2021): 23–32. http://dx.doi.org/10.52142/omujecm.38.si.gastro.3.

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Bleeding from the lower part of the digestive system that appears as hematochezia (fresh blood, clot or cherry-coloured stool) or melena (dark-coloured tarry stool) is called lower gastrointestinal tract bleeding (lower GI bleeding) (or colonic bleeding). In the traditional definition, lower GI bleeding was generally classified as bleeding distal to the Treitz ligament (duodenojejunal junction) as the border. In the last decade, GI bleeding has adopted three categories in some recent publications: Upper, middle, and lower. According to this category, bleeding from a source between the Treitz l
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Pannach, Sven, Julia Goetze, Luise Tittl, et al. "Localization, Management, Resource Consumption and Outcome of Major Gastrointestinal Bleeding in Patients with Direct Oral Anticoagulants, Vka and Antiplatelet Therapy." Blood 128, no. 22 (2016): 141. http://dx.doi.org/10.1182/blood.v128.22.141.141.

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Abstract Background Gastrointestinal bleeding (GI-B) is the most common major bleeding complication in oral anticoagulation. While direct oral anticoagulants (DOACs) have been shown to significantly decrease major bleeding, intracranial hemorrhage and fatal bleeding compared to vitamin k antagonists (VKA), there is conflicting evidence regarding the relative risk of GI-B. However, while bleeding rates are important, the exact localization of GI-B, the management, resource consumption and outcome of DOAC-associated GI-B could be even more important from a clinical perspective, but such data are
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Ghosh, Nalini Kanta, Ashish Singh, Rahul Rahul, Rajneesh Kumar Singh, Amit Goel, and Rajan Saxena. "Multifocal Small Bowel Angioectasias: Managed with Innovative, Nonresectional Surgical Procedure." Surgery Journal 08, no. 03 (2022): e169-e173. http://dx.doi.org/10.1055/s-0042-1744151.

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AbstractGastrointestinal (GI) angioectasias/angiodysplasias are the most frequent vascular lesions of GI tract, responsible for ∼5 to 6% of GI bleedings. It commonly involves the small bowel, making it difficult to diagnose and manage endoscopically. Though medical management has been used to prevent bleeding, it has only a limited role in acute severe hemorrhage. In such cases, surgical resection remains the only practical option. However, multiple lesions pose a unique challenge, as resection may not be advisable for long length of bowel involvement. Here, we report a case of recurrent GI bl
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10

Bossingham, D. H. "GI Bleeding and Rheumatologists." Journal of the Royal College of Physicians of London 26, no. 4 (1992): 461. https://doi.org/10.1016/s0035-8819(25)01140-7.

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11

Jagtap, Nitin, D. Nageshwar Reddy, and Manu Tandan. "Lower Gastrointestinal Bleeding." Journal of Digestive Endoscopy 13, no. 01 (2022): 014–18. http://dx.doi.org/10.1055/s-0042-1742694.

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AbstractLower gastrointestinal (LGI) bleeding indicates bleeding from colon or anorectum. Typically, patients with LGI bleeding present with bright red blood per rectum or hematochezia, although rarely they can present with melena as well. Alternatively, LGI bleeding is also defined as bleeding from a source within potential reach of a colonoscope, that is, colon and terminal ileum. LGI bleedings have more favorable outcomes than upper GI (UGI) bleeding and less common than UGI bleeding. Any patient presenting with GI bleeding should undergo a detailed history and physical examination for clue
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12

Mehta, Chirag, and Joy Chang. "Gastro-Intestinal Bleeding." InnovAiT: Education and inspiration for general practice 2, no. 5 (2009): 300–306. http://dx.doi.org/10.1093/innovait/inp016.

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Acute gastro-intestinal (GI) bleeding is defined as bleeding into the GI tract. GI bleeding is a common medical problem that can vary in presentation from being an insidious chronic blood loss to being potentially life threatening. Although 80% of acute GI bleeds stop spontaneously, it is essential to determine the source of bleeding and establish a diagnosis in order to attempt to prevent a recurrence and so that the most appropriate management may be given in future episodes. Also, an accurate diagnosis will allow a patient to be treated optimally for the underlying condition.
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13

Kadim, Muzal. "Gastroinstestinal Bleeding in Pediatrics." Archives of Pediatric Gastroenterology, Hepatology, and Nutrition 1, no. 2 (2022): 28–36. http://dx.doi.org/10.58427/apghn.1.2.2022.28-36.

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Gastrointestinal bleeding (GI) may occurs in infants and children. Most etiologies of GI bleeding are mild and self-limited, but may advance into life-threatening condition if not treated properly. Upper GI bleeding and lower GI bleeding can be classified based on bleeding sites that is above or below Treitz ligament. Causes of GI bleeding in infants and children varies according to their age and bleeding sites. Some conditions may be misunderstood as GI bleed such as consumption of certain red coloured food. Diagnosis of gastrointestinal bleeding in children includes complete history taking,
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14

Zaid Saad Abdul Alsattar, Fadil Agla Bonyan, Ahmed Salih Ahmed, and Laith G. Shareef. "Risk score for assessment of adults with acute gastrointestinal haemorrhage: A prospective study." GSC Biological and Pharmaceutical Sciences 13, no. 2 (2020): 225–31. http://dx.doi.org/10.30574/gscbps.2020.13.2.0376.

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Gastrointestinal (GI) bleeding has created an increasing demand for medical and surgical care; in addition, It is potentially serious and considered life-threatening in all age groups. This prospective study aims to find out the most common causes of GI bleedings, the incidence, the mode of treatment, and to investigate whether a simplified clinical score was able to predict the level of severity in the emergency department. About 170 patients aged (19 – 73) years who had been admitted to the emergency department in Baghdad teaching hospital were prospectively evaluated according to the causes
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15

Zaid, Saad Abdul Alsattar, Agla Bonyan Fadil, Salih Ahmed Ahmed, and G. Shareef Laith. "Risk score for assessment of adults with acute gastrointestinal haemorrhage: A prospective study." GSC Biological and Pharmaceutical Sciences 13, no. 2 (2020): 225–31. https://doi.org/10.5281/zenodo.4308198.

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Gastrointestinal (GI) bleeding has created an increasing demand for medical and surgical care; in addition, It is potentially serious and considered life-threatening in all age groups. This prospective study aims to find out the most common causes of GI bleedings, the incidence, the mode of treatment, and to investigate whether a simplified clinical score was able to predict the level of severity in the emergency department. About 170 patients aged (19 – 73) years who had been admitted to the emergency department in Baghdad teaching hospital were prospectively evaluated according to the
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16

Sherid, Muhammed, Samian Sulaiman, Salih Samo, et al. "Risk of Gastrointestinal Bleeding with Rivaroxaban: A Comparative Study with Warfarin." Gastroenterology Research and Practice 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/9589036.

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Introduction. The risk of gastrointestinal (GI) bleeding with rivaroxaban has not been studied extensively. The aim of our study was to assess this risk in comparison to warfarin.Methods. We examined the medical records for patients who were started on rivaroxaban or warfarin from April 2011 to April 2013.Results. We identified 300 patients (147 on rivaroxaban versus 153 on warfarin). GI bleeding occurred in 4.8% patients with rivaroxaban when compared to 9.8% patients in warfarin group(p=0.094). GI bleeding occurred in 8% with therapeutic doses of rivaroxaban (>10 mg/d) compared to 9.8% wi
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Choudaha, Anmol, Rajeev Kumar Banzal, Gunjan Kela Mehrotra, and Nandini Sodha. "Esophageal varices presenting as lower GI bleed in an infant: a rare presentation." International Journal of Contemporary Pediatrics 7, no. 6 (2020): 1428. http://dx.doi.org/10.18203/2349-3291.ijcp20202160.

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GI Bleeding is a common problem encountered in the emergency department and in the primary care settings. Lower GI Bleeding is relatively rare as compared to upper GI bleeding. Common causes of lower GI Bleeding are Polyp (32.5%), chronic nonspecific colitis (20.7%), lymphoid nodular hyperplasia (20%), Proctitis (18.2%), Solitary rectal ulcer (10%), Inflammatory bowel disease (6.5%).Among the various causes of lower GI Bleeding, esophageal varices is a rare cause. One such case presented to us with lower GI bleeding, on further evaluation was found to having esophageal varices due to portal hy
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18

Vafaeimanesh, Jamshid, Hassan Rakhshandeh, Ali Pourakbar, and Seyed MousalReza Hosseini. "The Effect of Hemostasis Powder® on Treatment of Bleeding from Benign Ulcers of Upper Gastrointestinal Tract; A Pilot Study." Middle East Journal of Digestive Diseases 11, no. 2 (2019): 84–89. http://dx.doi.org/10.15171/mejdd.2018.132.

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BACKGROUND Gastrointestinal (GI) bleeding is one of the most prevalent internal medical emergencies. Despite using several methods of treatment, effective treatment cannot be achieved in some patients. Hemostasis powder® is a mineral-herbal product. This emulsion was able to coagulate blood in, in vitro studies and also was effective in the treatment of mucosal and cutaneous bleeding in animal studies, without any toxicity. We decided to compare its effect on the treatment of human GI bleeding with the other common method for treatment of GI bleeding "argon plasma coagulation plus epinephrine
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19

Hibiya, Shuji, Takashi Fujii, Toshimitsu Fujii, et al. "COVID-19 severity is associated with the risk of gastrointestinal bleeding." BMJ Open Gastroenterology 10, no. 1 (2023): e001199. http://dx.doi.org/10.1136/bmjgast-2023-001199.

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ObjectiveThe association between the severity of COVID-19 and gastrointestinal (GI) bleeding is unknown. This study aimed to determine whether the severity of COVID-19 is a risk factor for GI bleeding.DesignA multicentre, retrospective cohort study was conducted on hospitalised patients with COVID-19 between January 2020 and December 2021. The severity of COVID-19 was classified according to the National Institute of Health severity classification. The primary outcome was the occurrence of GI bleeding during hospitalisation. The main analysis compared the relationship between the severity of C
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20

Deitelzweig, Steven, Allison Keshishian, Amiee Kang, et al. "Burden of major gastrointestinal bleeding among oral anticoagulant-treated non-valvular atrial fibrillation patients." Therapeutic Advances in Gastroenterology 14 (January 2021): 175628482199735. http://dx.doi.org/10.1177/1756284821997352.

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Background: Gastrointestinal (GI) bleeding is the most common type of major bleeding associated with oral anticoagulant (OAC) treatment. Patients with major bleeding are at an increased risk of a stroke if an OAC is not reinitiated. Methods: Non-valvular atrial fibrillation (NVAF) patients initiating OACs were identified from the Centers for Medicare and Medicaid Services ( CMS) Medicare data and four US commercial claims databases. Patients who had a major GI bleeding event (hospitalization with primary diagnosis of GI bleeding) while on an OAC were selected. A control cohort of patients with
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21

Urashima, Mitsuyoshi, Shigeru Toyoda, Toshiyuki Nakano, et al. "BUN/Cr Ratio as an Index of Gastrointestinal Bleeding Mass in Children." Journal of Pediatric Gastroenterology and Nutrition 15, no. 1 (1992): 89–92. http://dx.doi.org/10.1002/j.1536-4801.1992.tb10607.x.

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SummaryDetermining the site and severity of blood loss is important in the management of children with gastrointestinal (GI) bleeding. Blood urea nitrogen (BUN) and serum creatinine (Cr) were measured on the day of hospitalization and the ratio of BUN/Cr was calculated in 11 children with 16 episodes of upper GI bleeding and 49 with lower GI bleeding. There was a significant difference between the two GI bleeding groups with regard to BUN/ Cr ratio (p ≥ 0.001). When the ratio was 30 or above, the specificity of upper GI bleeding was 98% with a sensitivity of 68.8%. A linear relationship was fo
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22

Mohammadinejad, Payam, Lukasz Kwapisz, Jeff L. Fidler, et al. "The utility of a dual-phase, dual-energy CT protocol in patients presenting with overt gastrointestinal bleeding." Acta Radiologica Open 10, no. 7 (2021): 205846012110306. http://dx.doi.org/10.1177/20584601211030658.

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Background Due to their easy accessibility, CT scans have been increasingly used for investigation of gastrointestinal (GI) bleeding. Purpose To estimate the performance of a dual-phase, dual-energy (DE) GI bleed CT protocol in patients with overt GI bleeding in clinical practice and examine the added value of portal phase and DE images. Materials and Methods Consecutive patients with GI bleeding underwent a two-phase DE GI bleed CT protocol. Two gastroenterologists established the reference standard. Performance was estimated using clinical CT reports. Three GI radiologists rated confidence i
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23

Schmiderer, Andreas, Hubert Schwaighofer, Lukas Niederreiter, et al. "Decline in acute upper gastrointestinal bleeding during COVID-19 pandemic after initiation of lockdown in Austria." Endoscopy 52, no. 11 (2020): 1036–38. http://dx.doi.org/10.1055/a-1178-4656.

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Background COVID-19 has spread rapidly around the world. The Austrian government implemented a lockdown on 16 March to contain further spread of the disease. We investigated the effects of lockdown on acute upper gastrointestinal (GI) bleeding in Austria. Methods We contacted 98 Austrian hospitals performing emergency endoscopies. The hospitals were asked to report upper GI endoscopies performed for recent hematemesis, melena, or both, and exhibiting endoscopically visible signs of bleeding. The study period was from 3 weeks before (calendar Week 9) to 3 weeks after (Week 14) initiation of the
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Wallvik, Niklas, Joakim Eriksson, Jonas Höijer, et al. "Optimal timing of vitamin K antagonist resumption after upper gastrointestinal bleeding." Thrombosis and Haemostasis 117, no. 03 (2017): 491–99. http://dx.doi.org/10.1160/th16-07-0498.

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SummaryThe optimal timing of vitamin K antagonists (VKAs) resumption after an upper gastrointestinal (GI) bleeding, in patients with continued indication for oral anticoagulation, is uncertain. We included consecutive cases of VKA-associated upper GI bleeding from three hospitals retrospectively. Data on the bleeding location, timing of VKA resumption, recurrent GI bleeding and thromboembolic events were collected. A model was constructed to evaluate the ‘total risk’, based on the sum of the cumulative rates of recurrent GI bleeding and thromboembolic events, depending on the timing of VKA res
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25

Komarov, A. L., O. O. Shakhmatova, and V. V. Korobkova. "The balance of benefit and risk in prescribing antithrombotic therapy for patients with coronary artery disease. How to deal with the gastrointestinal bleeding problem?" Kardiologiia 60, no. 7 (2020): 115–24. http://dx.doi.org/10.18087/cardio.2020.7.n1159.

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The review focuses on upper gastrointestinal (GI) bleeding in patients with ischemic heart disease (IHD) receiving an antithrombotic therapy. Approaches to risk stratification for GI bleeding and correction of modifiable factors that determine the probability of such events are addressed in detail. Recommendations are provided for administration of stomach-protecting drugs. The interrelation of risk factors for thromboses and bleedings is stressed, and possible indications for a multicomponent antithrombotic therapy in patients with stable IHD are discussed.
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Tsagianni, Anastasia, Margaret V. Ragni, Diane M. Comer, and Jonathan G. Yabes. "Von Willebrand Disease and Gastrointestinal Bleeding: A National Inpatient Sample (NIS) Study." Blood 132, Supplement 1 (2018): 1179. http://dx.doi.org/10.1182/blood-2018-99-111731.

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Abstract Background:Von Willebrand disease (VWD) is a common congenital bleeding disorder, caused by defective or deficient von Willebrand factor (VWF), and characterized by mucosal bleeding. Among these, recurrent gastrointestinal (GI) bleeding may be serious and life-threatening,requiring hospitalization in 30%. Diagnosis and management remain challenging, and the prevalence and correlates of GI bleeding in VWD are not well understood. Methods. We conducted a cross-sectional study using discharge data from the National Inpatient Sample (NIS) between January 1, 2009 and December 31, 2014 to i
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Samanta, Arghya, Ujjal Poddar, Moinak Sen Sarma, Anshu Srivastava, Surender Kumar Yachha, and Samir Mohindra. "Endoscopic Band Ligation in Blue Rubber Bleb Nevus Syndrome: A Report of Two Children." JPGN Reports 4, no. 4 (2023): e344. http://dx.doi.org/10.1097/pg9.0000000000000344.

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Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disorder presenting with multifocal venous malformations of the skin, soft tissues, and gastrointestinal (GI) tract. Patients usually present with chronic anemia resulting from occult GI bleeding and sometimes with massive GI bleeding. We report 2 children with blue rubber bleb nevus syndrome with GI bleeding: 1 with obscure GI bleeding and the other with overt GI bleeding. In both cases, the presence of cutaneous lesions provided useful clues toward diagnosis. Colonoscopy and upper GI endoscopy revealed bluish polypoidal lesions in
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Tran, Nguyen H., Scott A. Soefje, Nivedita Rangarajan, et al. "Patient (pt) characteristics, treatment patterns, and outcomes in unresectable hepatocellular carcinoma (uHCC) treated with first-line (1L) systemic therapy in the United States (US)." Journal of Clinical Oncology 43, no. 4_suppl (2025): 572. https://doi.org/10.1200/jco.2025.43.4_suppl.572.

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572 Background: Guidelines recommend systemic therapy for uHCC ineligible for locoregional therapy. Until the approval of tremelimumab + durvalumab for uHCC, in Oct 2022, 1L systemic therapies in the US included multikinase inhibitors and atezolizumab (A) + bevacizumab (B). It is crucial to understand factors driving real-world treatment decisions and outcomes in uHCC. Characteristics, treatment patterns, and outcomes were assessed in US pts with uHCC treated with 1L systemic therapy. Methods: Data were collected from electronic medical records from US Mayo Clinic sites. Pts with uHCC who init
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29

Gupta, Alisha, Mihir M. Shah, Sudhir N. Kalaskar, and Matthew Kroh. "Late postoperative bleeding after Roux-en-Y gastric bypass: management and review of literature." BMJ Case Reports 11, no. 1 (2018): e226271. http://dx.doi.org/10.1136/bcr-2018-226271.

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Gastrointestinal (GI) bleeding is a catastrophic complication of gastric bypass. Bleeding can occur during the early or late phase after the operation. Though bleeding after gastric bypass is infrequent, late bleeding is exceedingly rare. We present two patients with late bleeding following Roux-en-Y gastric bypass (RYGB). The first patient, a 65-year-old woman, presented with life-threatening upper GI bleeding almost 5 years after laparoscopic RYGB. The second patient, a 62-year-old woman, presented with upper GI bleeding after almost 14 years following RYGB. Both, due to an eroding marginal
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30

Lee, K. W., H. S. Yoo, J. T. Lee, C. Y. Park, K. J. Sung, and J. S. Suh. "Radionuclide localization of GI bleeding." Journal of the Korean Radiological Society 21, no. 2 (1985): 246. http://dx.doi.org/10.3348/jkrs.1985.21.2.246.

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&NA;. "GI bleeding predictors now defined." Inpharma Weekly &NA;, no. 942 (1994): 16. http://dx.doi.org/10.2165/00128413-199409420-00035.

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32

Kirshan Ravi, Shri Jai, Priyanika Ravi, MD leonard Walsh, et al. "S682 New GI Bleeding Score." American Journal of Gastroenterology 116, no. 1 (2021): S307. http://dx.doi.org/10.14309/01.ajg.0000776260.40919.60.

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33

Liu, Raymond, and Sanjeeva P. Kalva. "Multidetector CT for GI Bleeding." Journal of Clinical Gastroenterology 46, no. 1 (2012): 6–7. http://dx.doi.org/10.1097/mcg.0b013e31823a4b2f.

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34

Waye, Jerome D., Giancarlo Caletti, Guido Costamagna, et al. "Hemostasis of upper GI bleeding." Gastrointestinal Endoscopy 56, no. 1 (2002): 159–61. http://dx.doi.org/10.1067/mge.2002.122034.

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Lane, Joshua E., Mohammed Ajjan, and Shahriar Sedghi. "GI bleeding from duodenal diverticula." American Journal of Gastroenterology 96, no. 9 (2001): 2799–800. http://dx.doi.org/10.1111/j.1572-0241.2001.04146.x.

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36

Longstreth, George F. "Colonoscopy and lower GI bleeding." American Journal of Gastroenterology 97, no. 1 (2002): 203–4. http://dx.doi.org/10.1111/j.1572-0241.2002.05402.x.

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&NA;. "SSRIs Associated with GI Bleeding." Emergency Medicine News 31, no. 9 (2009): 9. http://dx.doi.org/10.1097/01.eem.0000360589.48644.14.

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Guilbeau-Brand, Claudia. "GI Bleeding Tips for Success." Gastroenterology Nursing 30, no. 2 (2007): 152. http://dx.doi.org/10.1097/01.sga.0000267985.80635.43.

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Voss, Glenn D., and Pamela Schweitzer. "GI bleeding associated with nabumetone." American Journal of Health-System Pharmacy 51, no. 19 (1994): 2506–8. http://dx.doi.org/10.1093/ajhp/51.19.2506.

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Morello, Frank A. "GI Bleeding: Current Approach (CC)." Journal of Vascular and Interventional Radiology 15, no. 2 (2004): P184—P185. http://dx.doi.org/10.1016/s1051-0443(04)70206-7.

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Heller, Stephen J., Jeffrey L. Tokar, Minhhuyen T. Nguyen, Oleh Haluszka, and David S. Weinberg. "Management of bleeding GI tumors." Gastrointestinal Endoscopy 72, no. 4 (2010): 817–24. http://dx.doi.org/10.1016/j.gie.2010.06.051.

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42

Wilke, W. S., and L. Laine. "GI bleeding: identifying the source." Cleveland Clinic Journal of Medicine 61, no. 6 (1994): 407–8. http://dx.doi.org/10.3949/ccjm.61.6.407.

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43

Campbell, Amy M. "Manage acute upper GI bleeding." Nursing 38, ED Insider (2008): 1–2. http://dx.doi.org/10.1097/01.nurse.0000314637.72344.00.

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44

Ahmed, Adel F., and Abdulwahab M. Gabal. "OBSCURE CAUSE OF GI BLEEDING." American Journal of Gastroenterology 99 (October 2004): S292. http://dx.doi.org/10.14309/00000434-200410001-00889.

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45

McCarthy, Denis M. "GI bleeding: problems that persist." Gastrointestinal Endoscopy 70, no. 2 (2009): 225–28. http://dx.doi.org/10.1016/j.gie.2008.12.247.

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46

Sengupta, Neil, David M. Kastenberg, David H. Bruining, et al. "The Role of Imaging for Gastrointestinal Bleeding: Consensus Recommendations From the American College of Gastroenterology and Society of Abdominal Radiology." American Journal of Gastroenterology 119, no. 3 (2023): 438–49. http://dx.doi.org/10.14309/ajg.0000000000002631.

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Gastrointestinal (GI) bleeding is the most common GI diagnosis leading to hospitalization within the United States. Prompt diagnosis and treatment of GI bleeding is critical to improving patient outcomes and reducing high healthcare utilization and costs. Radiologic techniques including computed tomography angiography, catheter angiography, computed tomography enterography, magnetic resonance enterography, nuclear medicine red blood cell scan, and technetium-99m pertechnetate scintigraphy (Meckel scan) are frequently used to evaluate patients with GI bleeding and are complementary to GI endosc
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47

Roberts, Jonathan C., Miguel A. Escobar, Suchitra Acharya Acharya, et al. "Retrospective Chart Review of Gastrointestinal Bleeding in Patients with Von Willebrand Disease." Blood 136, Supplement 1 (2020): 20–21. http://dx.doi.org/10.1182/blood-2020-133499.

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Background: Recurrent overt or occult gastrointestinal (GI) bleeding is a serious complication of von Willebrand Disease (VWD) and is the most common cause of hospitalization for patients with VWD. Data from the VWD Prophylaxis Network (VPN) emphasized the importance of prophylaxis in minimizing bleeding episodes in VWD; however, the management of GI bleeding in these patients remains challenging. Despite the availability of von Willebrand factor (VWF) replacement therapy, GI bleeding may be refractory and require the use of multiple treatment approaches. Currently, there are limited published
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48

Chien, Yu-Wen, Hui-Ning Chuang, Yu-Ping Wang, Guey Chuen Perng, Chia-Yu Chi, and Hsin-I. Shih. "Short-term, medium-term, and long-term risks of nonvariceal upper gastrointestinal bleeding after dengue virus infection." PLOS Neglected Tropical Diseases 16, no. 1 (2022): e0010039. http://dx.doi.org/10.1371/journal.pntd.0010039.

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Dengue patients have an increased risk of acute gastrointestinal (GI) bleeding. However, whether dengue virus (DENV) infection can cause an increased long-term risk of GI bleeding remains unknown, especially among elderly individuals who commonly take antithrombotic drugs. A retrospective population-based cohort study was conducted by analyzing the National Health Insurance Research Databases. Laboratory-confirmed dengue patients from 2002 to 2012 and four matched nondengue controls were identified. Multivariate Cox proportional hazard regression was used to evaluate the acute (<30 days), m
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Fereshteh, Jaferi* Prabej Pandit Geetha K. M. Susheela Rani S. Bhavana Sunethri Aarathi-R. "A PROSPECTIVE STUDY ON GASTRIC BLEEDING AND DRUG INTERACTIONS ASSOCIATED WITH ANTICOAGULANT THERAPY AT CARDIOLOGY DEPARTMENT OF A TERTIARY CARE HOSPITAL." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 3991–98. https://doi.org/10.5281/zenodo.1043936.

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Abstract:
Background: Anticoagulants are the class of drugs that are used to prevent thrombus extension and embolic complications by reducing the rate of fibrin formation. They do not dissolve already formed clot but prevent recurrences. Method: A total of 200 patients were included in these prospective, uni-centric, observational studies who were suffering from Cardiovascular Diseases, from the cardiology inpatient department at a tertiary care hospital in Bangalore. Results: It was observed that out of 200 patients included in the study, 122 (61%) patients were treated with anticoagulants and antiplat
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50

Pinzon, Rizaldy Taslim, and Carmelia Anggraini. "A RETROSPECTIVE COHORT STUDY ON THE RISK FACTORS OF GASTROINTESTINAL BLEEDING IN ACUTE ISCHEMIC STROKE PATIENTS WITH ATRIAL FIBRILLATION." Romanian Journal of Neurology 20, no. 2 (2021): 204–10. http://dx.doi.org/10.37897/rjn.2021.2.12.

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Abstract:
Introduction. Gastrointestinal (GI) bleeding is a serious complication of stroke causing high morbidity. Atrial fibrillation is associated with both ischemic stroke and GI bleeding due to usage of anticoagulant. The aim of this study is to determine the risk factors of GI bleeding in ischemic stroke patients with atrial fibrillation. Material and methods. All ischemic stroke patients with atrial fibrillation from January 2017 to December 2018 were extracted from our hospital-based stroke registry. We extracted demographical characteristic, subtypes of stroke, and medication history. Results. W
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