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Journal articles on the topic 'Gingival crevicular fluid and peri-implant crevicular fluid'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Rui, HUANG, JingxinMO, CHEN Xufeng, ZHU Shumin, and RenfaLAI. "PROGRESS IN THE STUDY OF GINGIVAL CREVICULAR FLUID BIOMARKERS FOR THE DIAGNOSIS OF PERI-IMPLANT DISEASE." International Journal of Sciences and Applied Research 9, no. 1 (2022): 01–09. https://doi.org/10.5281/zenodo.6404451.

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A recent study of patients undergoing implant surgery showed a significant increase in the prevalence of peri-implant disease, with peri-implant mucositis and peri-implantitis predominating. Peri-implant disease mostly appears after several years of implant use. Currently, the diagnosis of peri-implant disease relies on peri-implant soft tissue exploration and imaging, but abnormalities in these indicators only occur when tissue destruction has already occurred and cannot predict whether an implant has the potential to develop peri-implant disease. Therefore, the early diagnosis of peri-implan

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Olgun, Ebru, Kubilay Barış, and Meltem Karşıyaka Hendek. "Gingival crevicular fluid and peri-implant sulcus fluid." Journal of Dental Sciences and Education 1, no. 3 (2023): 98–100. http://dx.doi.org/10.51271/jdse-0017.

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Gingival crevicular fluid (GCF) is an important source for the assessment of periodontal and peri-implant disease activity and response to periodontal therapy. GCF contains cellular components such as epithelium, bacteria, leukocytes, erythrocytes, viruses and their by-products, electrolytes, bacterial metabolic products, host and bacterial enzymes, and enzyme inhibitors such as acid phosphatase, alkaline phosphatase, cytokines, and immunoglobulins. In addition, it is also found that drugs taken systemically pass into the GCF.

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3

Rakic, Mia, Natasa Nikolic-Jakoba, Xavier Struillou, et al. "Receptor activator of nuclear factor kappa B (RANK) as a determinant of peri-implantitis." Vojnosanitetski pregled 70, no. 4 (2013): 346–51. http://dx.doi.org/10.2298/vsp1304346r.

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Background/Aim. Peri-implantitis presents inflammatory process that affects soft and hard supporting tissues of osseointegrated implant based on inflammatory osteoclastogenesis. The aim of this study was to investigate whether receptor activator of nuclear factor kappa B (RANK) concentrations in peri-implant crevicular fluid could be associated with clinical parameters that reflect inflammatory nature of peri-implantitis. Methods. The study included 67 patients, 22 with diagnosed peri-implantitis, 22 persons with healthy peri-implant tissues and 23 patients with periodontitis. Clinical paramet

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Bahadur, Saikiran, Aseem Sharma, Omar Basheer Altaher Mohammed, et al. "Effect of diode laser on peri-implantitis by monitoring gingival crevicular fluid levels." Bioinformation 21, no. 1 (2025): 96–99. https://doi.org/10.6026/973206300210096.

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Untreated peri-implantitis results into implant failure. Therefore, it is of interest to assess the effect of diode laser on peri-implantitis and levels of crevicular fluid biomarkers. Hence, this study involved 20 participants, with a total of 24 dental implants exhibiting peri-implantitis on the laser group (n = 10) and the control group (n = 10). Clinical parameters around the implants were evaluated and samples of peri-implant crevicular fluid (PICF) were collected at baseline, as well as at 3-month and 6-month follow-up intervals. These groups exhibited significant differences in terms of

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Faria, Juliana Barbosa de, Taíssa Cássia de Souza Furtado, Thaís Soares Farnesi de Assunção, et al. "Immunological evaluation of the crevicular fluid in patients with gingivitis, periodontitis, and peri-implantitis: a 1-year cross-sectional study." Research, Society and Development 10, no. 13 (2021): e41101320756. http://dx.doi.org/10.33448/rsd-v10i13.20756.

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Objective: To assess the levels of IL-12, IL-15, IL-18, and IL-32 in the gingival crevicular fluid (GCF) and peri-implant crevicular fluid (PICF) in patients with gingivitis, periodontitis, and peri-implantitis before and one year after implant installation. Material and Methods: Forty-nine samples of GCF and PICF were collected from March 2018 to March 2019. The patients were classified: patients with gingivitis (n=7), patients with periodontitis (n=14), patients with peri-implantitis (n=4) and healthy patients (n=24). The crevicular fluid from the 49 patients was collected before implant ins

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Motta, Sergio Henrique Gonçalves, Cristiane Ferreira Pinto Paterline Vivacqua, Leonardo Emiliano dos Santos, et al. "Biological sealing aspects surrounding anterior crowns on dental implants: clinical and photographic cases report." Revista Fluminense de Odontologia 2, no. 61 (2023): 91–106. http://dx.doi.org/10.22409/ijosd.v2i61.57026.

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The biological sealing (BS) around implants is a dominant factor to determine the long-term success of peri-implant health. There are several features of the BS around implants in common with the soft tissue attached to teeth, such as the presence of crevicular fluid, acquired pellicle, epithelium; otherwise, the quality of the BS around implants is weaker compared with the junctional epithelium of natural teeth. Then, this article aimed to describe three cases report showing the presence of a BS (cuticle-crevice fluid-acquired pellicle) around the fixed crowns on dental implants in the anteri

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Yakar, Nil, Guliz N. Guncu, Abdullah C. Akman, Aslı Pınar, Erdem Karabulut, and Rahime M. Nohutcu. "Evaluation of gingival crevicular fluid and peri-implant crevicular fluid levels of sclerostin, TWEAK, RANKL and OPG." Cytokine 113 (January 2019): 433–39. http://dx.doi.org/10.1016/j.cyto.2018.10.021.

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Narayankar, Ashwini, Sagar Kumar Kashyap, Suman Yadav, et al. "Evaluation N-Telopeptide (NTx) and calprotectin level in crevicular fluid with peri-implantitis." Bioinformation 20, no. 9 (2024): 1183–86. https://doi.org/10.6026/9732063002001183.

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Following inflammation and bone loss near the implant site, peri-implantitis develops. N-Telopeptide (NTx) and Calprotectin are abundant in the crevicular fluids found in that area, and are thought to be possible biomarkers. Therefore, it is of interest to evaluate the amounts of calprotectin and NTx in the peri-implant sulcular fluid (PISF) from implant sites with or without peri-implantitis. Twenty healthy individuals and twenty patients with peri-implantitis who had a single dental implant were included in the total of forty participants. For every patient, the peri-implant clinical paramet

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Al-Majid, Ahmed, Saeed Alassiri, Nilminie Rathnayake, Taina Tervahartiala, Dirk-Rolf Gieselmann, and Timo Sorsa. "Matrix Metalloproteinase-8 as an Inflammatory and Prevention Biomarker in Periodontal and Peri-Implant Diseases." International Journal of Dentistry 2018 (September 16, 2018): 1–27. http://dx.doi.org/10.1155/2018/7891323.

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Levels of and especially the degree of activation of matrix metalloproteinase (MMP-8) in oral fluids (i.e., saliva, mouth rinse, gingival crevicular fluid (GCF) and peri-implantitis sulcular fluid (PISF)) increase to pathologically elevated levels in the periodontal and peri-implant diseases. This study aimed at collecting and collating data from previously published studies and determining whether active MMP-8 (aMMP-8) could serve as a biomarker for the diagnosis and prevention of periodontal and peri-implant diseases. The literature search identified a total of 284 articles. Out of 284 artic

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Bevilacqua, Lorenzo, Matteo De Biasi, Maria Giulia Lorenzon, Costanza Frattini, and Daniele Angerame. "Volumetric Analysis of Gingival Crevicular Fluid and Peri-Implant Sulcus Fluid in Healthy and Diseased Sites: A Cross-Sectional Split-Mouth Pilot Study." Open Dentistry Journal 10, no. 1 (2016): 131–38. http://dx.doi.org/10.2174/1874210601610010131.

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Background:Researchers have recently drawn attention to the analysis of gingival crevicular fluid (GCF) and peri-implant sulcus fluid (PISF) for the implementation of the diagnosis of periodontal and peri-implant disease. Nevertheless, the measurements of volume and biomarkers concentration can be critically biased when data collected from studies with parallel group design are compared, given the technical difficulties, methodological variables, as well as the variability of crevicular fluid characteristics among different individuals.Objective:The aim of the present study was to assess the G

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Adonogianaki, E., J. Mooney, J. L. Wennstrom, U. Lekholm, and D. F. Kinane. "Acute-phase proteins and immunoglobulin G against Porphyromonas gingivalis in peri-implant crevicular fluid: a comparison with gingival crevicular fluid." Clinical Oral Implants Research 6, no. 1 (1995): 14–23. http://dx.doi.org/10.1034/j.1600-0501.1995.060102.x.

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Bhardwaj, Smiti, and Munivenkatappa Lakshmaiah Venkatesh Prabhuji. "Comparative volumetric and clinical evaluation of peri-implant sulcular fluid and gingival crevicular fluid." Journal of Periodontal & Implant Science 43, no. 5 (2013): 233. http://dx.doi.org/10.5051/jpis.2013.43.5.233.

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Alassy, Hatem, Praveen Parachuru, and Larry Wolff. "Peri-Implantitis Diagnosis and Prognosis Using Biomarkers in Peri-Implant Crevicular Fluid: A Narrative Review." Diagnostics 9, no. 4 (2019): 214. http://dx.doi.org/10.3390/diagnostics9040214.

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Dental implant diseases, peri-implantitis (PI) and peri-implant mucositis (PIM), have shown wide prevalence in recent studies. Despite the prevalence, diagnosing peri-implant disease (PID) remains challenging as common diagnostic methods of periodontal probing and radiographs may be inaccurate. These methods only document pre-existing destruction rather than current disease activity. Furthermore, there is no current model to predict the progression of PID. Though a predictive model is lacking, biomarkers may offer some potential. Biomarkers are commonly used in medicine to objectively determin

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Alassiri, Saeed, Pirjo Parnanen, Nilminie Rathnayake, et al. "The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases." Disease Markers 2018 (August 5, 2018): 1–5. http://dx.doi.org/10.1155/2018/1306396.

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The analysis of the disease-specific oral and systemic biomarkers in saliva and oral fluids (i.e., mouth rinse, gingival crevicular fluid (GCF), and peri-implantitis fluid (PISF)) is demanding. Several hosts and microbial factors may influence their expression, release, and levels. The type of saliva/oral fluids utilized for the diagnostics affects the analysis. High sensitivity and specificities together with sophisticated methods and techniques are essential for valuable outcome. We describe here recently developed practical, convenient, inexpensive, noninvasive, and quantitative mouth rinse

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Nogueira-Filho, Getulio, Igor Pesun, Cindy Isaak-Ploegman, Manjula Wijegunasinghe, Tom Wierzbicki, and Christopher A. McCulloch. "Longitudinal Comparison of Cytokines in Peri-Implant Fluid and Gingival Crevicular Fluid in Healthy Mouths." Journal of Periodontology 85, no. 11 (2014): 1582–88. http://dx.doi.org/10.1902/jop.2014.130642.

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Aleksandrowicz, Paweł, Paulina Żelechowska, Justyna Agier, et al. "Evaluation of Metalloproteinase-8 Levels in Crevicular Fluid of Patients with Healthy Implants or Periodontitis." Mediators of Inflammation 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/4920847.

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Evaluation of periodontal and peri-implant tissue condition is mainly based on clinical examination and imaging diagnostics. Some data imply that Metalloproteinase-8 (MMP-8) level examination in peri-implant sulcular fluid (PISF) might be useful for evaluating the condition of peri-implant tissues and monitoring a development of peri-implant inflammation, including both mucositis and peri-implantitis. Hence, in this study, we decided to evaluate the level of MMP-8 in PISF obtained from patients without clinical symptoms of mucositis or peri-implantitis and compare it with MMP-8 level in gingiv

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Guarnieri, Renzo, Rodolfo Reda, Dario Di Nardo та ін. "Expression of IL-1β, IL-6, TNF-α, and a-MMP-8 in sites with healthy conditions and with periodontal and peri-implant diseases: A case-control study". Journal of Dental Research, Dental Clinics, Dental Prospects 18, № 2 (2024): 135–42. http://dx.doi.org/10.34172/joddd.40958.

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Background. This study evaluated the gingival crevicular fluid (GCF) and Peri- implant crevicular fluid (PICF) concentrations of interleukin-1 beta (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and active metalloproteinase-8 (a-MMP-8) in sites with healthy conditions vs. sites affected by periodontitis (PER) and peri-implantitis (PIM). Methods. Periodontally healthy (PH) sites with PER, sites with peri-implant health (PIH), and sites with PIM were investigated intra-individually, according to the inclusion criteria of each group. Probing pocket depth (PPD), plaque index, g

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Yu, Shu-Juan, Wen-Ling Shan, Yu-Xiao Liu, Xiao-Yan Huang, and Guo-Xiong Zhu. "Effects of Four Different Crown Materials on the Peri-Implant Clinical Parameters and Composition of Peri-Implant Crevicular Fluid." Journal of Oral Implantology 43, no. 5 (2017): 337–44. http://dx.doi.org/10.1563/aaid-joi-d-16-00116.

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This study aimed to identify the preferred crown material by measuring the peri-implant clinical parameters and the concentrations of receptor activator of nuclear factor-κB ligand (RANKL), osteoprotegerin (OPG), and calcium in peri-implant crevicular fluid (PICF) with 4 different crown materials. A total of 196 patients with a single missing posterior tooth received crown restoration with cobalt-chromium (Co-Cr) porcelain-fused-to-metal (PFM; n = 50), aurum platinum (Au-Pt) PFM (n = 48), titanium (Ti) PFM (n = 52), or zirconia (Zi) all-ceramic crown (n = 46). Fifty-one natural counterpart tee

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Viridiana, Altamirano Paredes, Aurora Macín Cabrera Susana, Estela Castrillón Rivera Laura, Ismael Castañeda Sánchez Jorge, and de Jesús Juárez Sandoval José. "Interleukin-13 Assessment in Gingival Crevicular Fluid of Patients with Periodontal Disease." RA JOURNALS OF APPLIED RESEARCH 11, no. 03 (2025): 184–89. https://doi.org/10.5281/zenodo.15062808.

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ABSTRACT: The present study holds significant potential to assess interleukin 13 (IL-13) levels in Crevicular Gingival Fluid (CGF) as a potential immunological marker for bone remodeling in subjects with periodontal disease. Thirty-nine subjects were included, with 19 diagnosed with gingivitis and 20 with periodontitis. The latter were classified following the new classification of periodontal and peri-implant diseases in stages I (6%), II (6%), III (6%), and IV (2%). Crevicular gingival fluid was meticulously collected with filter paper strips. Volume quantification was obtained with Periotro

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Friedmann, Anton, Magdalena Friedrichs, Dogan Kaner, Bernd-Michael Kleber, and Jean-Pierre Bernimoulin. "Calprotectin and cross-linked N-terminal telopeptides in peri-implant and gingival crevicular fluid." Clinical Oral Implants Research 17, no. 5 (2006): 527–32. http://dx.doi.org/10.1111/j.1600-0501.2006.01251.x.

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Räisänen, Ismo T., Nur Rahman Ahmad Seno Aji, Dimitra Sakellari, et al. "Active Matrix Metalloproteinase-8 (aMMP-8) Versus Total MMP-8 in Periodontal and Peri-Implant Disease Point-of-Care Diagnostics." Biomedicines 11, no. 11 (2023): 2885. http://dx.doi.org/10.3390/biomedicines11112885.

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Active matrix metalloproteinase-8 (aMMP-8) is a promising biomarker candidate for the modern periodontal and peri-implant disease diagnostics utilizing the chairside/point-of-care oral fluid technologies. These rapid biomarker analysis technologies utilize gingival crevicular fluid (GCF), peri-implant sulcular fluid (PISF), or mouth rinse as the oral fluid matrices that can be collected patient-friendly and non-invasively without causing bacteremia. aMMP-8, but not total or latent proMMP-8, has been shown to be a relevant biomarker to be implemented to the latest 2017 classification system of

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Hamad-Ameen, Rezhna Muhammed, and Othman Abu-Bakr Omer. "Impact of diabetes mellitus on dental implants: A cross sectional controlled clinical study." Erbil Dental Journal 6, no. 2 (2023): 203–14. http://dx.doi.org/10.15218/edj.2023.22.

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Background and objective: After osseointegration the long-term success of dental implants is determined by the maintenance of the peri-implant soft tissue and bone level. This study evaluates the impact of Diabetes mellitus on dental implants in diabetic patients and compare it with that of nondiabetic patients. Patients and methods: Thirty diabetic patients and thirty controlled subjects rehabilitated with dental implants were included in this study. The duration of implant treatment is (1-7) years, and dental implant status between both groups was compared using Immunohistochemistry for anal

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Negahdari, Ramin, Mahdi Rahbar, Vahid Fakhrzadeh, Hosein Eslami, Taleb Akbari, and Sepideh Bohluli. "Comparison of Proinflammatory Cytokine Levels in Gingival Crevicular Fluid around Dental Implants with Ceramic and Titanium Abutments." Journal of Contemporary Dental Practice 18, no. 9 (2017): 831–36. http://dx.doi.org/10.5005/jp-journals-10024-2135.

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ABSTRACT Background Considering the high success rate of osseointegration, there is ever-increasing use of dental implants. The mechanisms and biologic response of peri-implant tissues are different depending on the biocompatibility of the implant material. The aim of this study was to compare the proinflammatory cytokine levels in the gingival crevicular fluid (GCF) around dental implants with ceramic and titanium abutments. Materials and methods All the patients with dental implants referring to two private offices of two prosthodontists from June to August 2016 were examined in relation to

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Sarı, Emel, та Cihan Uçar. "Interleukin 1β Levels around Microscrew Implants during Orthodontic Tooth Movement". Angle Orthodontist 77, № 6 (2007): 1073–78. http://dx.doi.org/10.2319/100506-405.1.

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Abstract Objective: To determine whether interleukin 1β (IL-1β) levels are elevated around microscrew implants that are used as anchorage for tooth movement. Materials and Methods: Ten young adults, aged 16.3 ± 2.5 years and with all four premolars extracted , comprised the study group. Twenty maxillary microscrew implants were placed bilaterally in the alveolar bone between the maxillary second premolars and first molars as anchorage units for distal movement of the maxillary canines. The maxillary canines served as the treatment group, and the microscrew implants were designated as the impla

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Xu, Ling, Zhao Yu, Hsi-Ming Lee, et al. "Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study." Acta Odontologica Scandinavica 66, no. 4 (2008): 219–24. http://dx.doi.org/10.1080/00016350802183393.

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Wahab, Deniarti, Dewi Ayuningtyas, Yuniarti Soeroso, Benso Sulijaya, Dimas Ilham Hutomo, and Cortino Sukotjo. "Analysis of clinical parameter and tumor necrosis factor-alpha levels on keratinized tissue around implant and tooth." Journal of Indian Society of Periodontology 27, no. 2 (2023): 160–66. http://dx.doi.org/10.4103/jisp.jisp_592_21.

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Abstract Background: Studies have shown the importance of keratinized tissue around implants to prevent peri-implant diseases. This study aims to analyze the correlation of keratinized tissue around implants and teeth with clinical parameter scores and tumor necrosis factor-alpha (TNF-α) levels. Materials and Methods: A cross-sectional study of 20 adults with 20 dental implants and 20 contralateral teeth that have functioned suprastructurally for more than 3 months without any systemic diseases. Keratinized tissue around implant and tooth was measured. The clinical examinations included the pl

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Nishikawa, Yasufumi, Yoritoki Tomotake, Hiromichi Kawano, et al. "Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts." International Journal of Molecular Sciences 24, no. 4 (2023): 3256. http://dx.doi.org/10.3390/ijms24043256.

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Candida albicans (Ca) is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of Ca in the pathogenesis of peri-implantitis remains unclear. In this study, we aimed to clarify Ca prevalence in the peri-implant sulcus and investigated the effects of candidalysin (Clys), a toxin produced by Ca, on human gingival fibroblasts (HGFs). Peri-implant crevicular fluid (PICF) was cultured using CHROMagar and Ca colonization rate and colony numbers were calculated. The levels of interleukin (IL)-1β an

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Al-Qufaish, M. A. M., I. N. Usmanova, M. М. Tuigunov, R. F. Khusnarizanova, M. I. Gumerova, and A. I. Shangareeva. "Optimization of periodontal disease diagnosis by the results of clinical laboratory tests." Parodontologiya 26, no. 2 (2021): 170–74. http://dx.doi.org/10.33925/1683-3759-2021-26-2-170-174.

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Relevance. The authors have established that the microbiological and local risk factors prevail in changing the clinical condition of the periodontium. Aim – сlinical and diagnosis argumentation of the gingival tissue condition according to the criteria of the New International Classification of Periodontal and Peri-implant Diseases and Conditions and Proceedings of the 2017 World Workshop jointly held together by the American Association of Periodontology (AAP) and the European Federation of Periodontology (EFP).Materials and methods. Clinical and laboratory assessment of 105 young patients w

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Maleki Dizaj, Solmaz, Hojjat Shokrgozar, Javad Yazdani, Mohammad Yousef Memar, Simin Sharifi, and Mohammad Ali Ghavimi. "Antibacterial Effects of Curcumin Nanocrystals against Porphyromonas gingivalis Isolated from Patients with Implant Failure." Clinics and Practice 12, no. 5 (2022): 809–17. http://dx.doi.org/10.3390/clinpract12050085.

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Background. Despite their benefits, dental implants may sometimes fail for a diversity of causes; the most common reasons of failure are infection and bone loss. Porphyromonas gingivalis (P. gingivalis) bacteria show a major role in peri-implantitis infection and dental implant failure. Methods. In this study, the prevalence of P. gingivalis isolated from the gingival crevicular fluid (GCF) of fifteen Iranian patients with implant failure (more than 1/3 of the implant length), who had average oral and dental hygiene and no antibiotic use for at least one month, was determined. Moreover, the an

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Alpaslan Yaylı, Nazlı Zeynep, and Eylem Ayhan Alkan. "Biochemical marker levels in peri-implant crevicular fluid of completely edentulous patients with two implant-supported mandibular overdentures before and 6 months after loading: Prospective clinical trial." International Dental Research 11, Suppl. 1 (2021): 160–66. http://dx.doi.org/10.5577/intdentres.2021.vol11.suppl1.24.

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Aim: The aim of this study was to determine the levels of biochemical markers detected in the peri-implant crevicular fluid (PICF) before and 6 months after loading in completely edentulous patients with two implant-supported mandibular overdentures and to correlate them with clinical parameters. Methodology: Two implants were applied to the mandibular canine region of the 20 completely edentulous and systemically healthy patients (11 females, 9 males) with conventional 2-stage surgery. PICF samples of the participants were collected before and 6 months after prosthetic loading, and clin

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Uzunkaya, Meral, and Hasan Gundogar. "Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional study." Annals of Medical Research 26, no. 10 (2019): 2093. http://dx.doi.org/10.5455/annalsmedres.2019.06.317.

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Song, Zhiming, Paul Weigl, and Bi Wang. "Correlations of inflammatory cytokines, oxidative stress markers, and matrix metalloproteinases in gingival crevicular fluid with peri-implantitis." European Journal of Inflammation 17 (January 2019): 205873921984554. http://dx.doi.org/10.1177/2058739219845542.

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This study aimed to analyze the correlations of inflammatory cytokines, oxidative stress markers, and matrix metalloproteinases (MMPs) in gingival crevicular fluid (GCF) with peri-implantitis (PI). Forty patients receiving dental implantation were enrolled. There were 52 implants, which were divided into PI group (42 implants) and health implant (HI) group (10 implants). Fifty-two healthy teeth (HT) with the same names with affected teeth in the patients were selected as the control group. The periodontal status was recorded. The GCF was collected and quantified. The levels of interleukin-6 (I

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Shama, MM, M. Aboukhadr, M. Madi, and S. Abdelhady. "COMPARISON BETWEEN LEVEL OF INTEREUKIN 10 IN THE GINGIVAL CREVICULAR FLUID AND PERI-IMPLANT SULCULAR FLUID AROUND HEALTHY DENTAL IMPLANTS (SPLIT MOUTH STUDY)." Alexandria Dental Journal 41, no. 1 (2016): 26–30. http://dx.doi.org/10.21608/adjalexu.2016.59168.

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Zhang, Qian, Haitao Xu, Na Bai, Fei Tan, Huirong Xu, and Jie Liu. "Matrix Metalloproteinase 9 is Regulated by LOX-1 and erk1/2 Pathway in Dental Peri-Implantitis." Current Pharmaceutical Biotechnology 21, no. 9 (2020): 862–71. http://dx.doi.org/10.2174/1389201021666200221121139.

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Background and Objective: Dental peri-implantitis, which can be caused by several different microbial factors, is characterized by inflammatory lesions of the surrounding hard and soft tissues of an oral implant. Matrix Metalloproteinase 9 (MMP9) is thought to be involved in the pathogenesis of peri-implantitis. However, the regulatory mechanism of MMP9 in peri-implantitis has not been fully elucidated. In this study, we tried to evaluate the regulatory mechanism of MMP9 in peri-implantitis. Methods: We collected Peri-Implant Crevicular Fluid (PICF) from ten healthy implants and ten periimplan

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Gao, Xiaowei, Jing Zhou, Yue Sun, Lin Wang, and Yanmin Zhou. "Differential expressions of biomarkers in gingival crevicular fluid of Han and Uygur populations with peri-implantitis." Medicine 97, no. 16 (2018): e0471. http://dx.doi.org/10.1097/md.0000000000010471.

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Güncü, Güliz N., Gülüzar Büyüktepe, Sezen B. AÕkin, Kamer Klllnç, Celal Tümer, and Tolga F. Tözüm. "Inpatient Evaluation of Periodontal, Esthetic and Inflammatory Parameters around Dental Implants and Natural Teeth." Journal of Contemporary Dental Practice 14, no. 1 (2013): 90–95. http://dx.doi.org/10.5005/jp-journals-10024-1277.

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ABSTRACT Aim The use of endosseous dental implants (DI) has become a successful treatment alternative. However, providing periimplant tissue health and achieving a natural esthetic look are important topics in this treatment. The aim of the present study was to evaluate periodontal and esthetic parameters around DI and natural teeth (NT) and also to analyze myeloperoxidase (MPO) levels in gingival crevicular fluid (GCF) and peri-implant sulcus fluid (PISF). Materials and methods Twenty DI supported fixed prosthesis and contralateral 20 NT were enrolled to the present study. Clinical periodonta

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Schierano, Gianmario, Giovanni Pejrone, Paola Brusco та ін. "TNF-α TGF-β2 and IL-1β levels in gingival and peri-implant crevicular fluid before and after de novo plaque accumulation". Journal of Clinical Periodontology 35, № 6 (2008): 532–38. http://dx.doi.org/10.1111/j.1600-051x.2008.01224.x.

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Tastan Eroglu, Zeynep, Dilek Ozkan Sen, and Elif Oncu. "Association of Peri-Implant Keratinized Mucosa Width and Mucosal Thickness with Early Bone Loss: A Cross-Sectional Study." Journal of Clinical Medicine 13, no. 7 (2024): 1936. http://dx.doi.org/10.3390/jcm13071936.

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Objective: The objective of this study was to evaluate the effects of keratinized mucosa width (KMW) and mucosal thickness (MT) around dental implants on marginal bone loss (MBL). The evaluation was performed one year after loading by comparing clinical, radiographic, and biochemical parameters. Methods: The study included 87 implants in 87 patients undergoing regular follow-ups without hard or soft tissue augmentation one year after loading. Clinical measurements included plaque index (PI), gingival index (GI), bleeding on probing (BoP), probing depth (PD), KMW, and MT. MBL was assessed with

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Liu, Min, Zhengmao Xu, and Hao Li. "Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis." BioMed Research International 2022 (October 3, 2022): 1–12. http://dx.doi.org/10.1155/2022/8065313.

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In order to solve the effect of orthodontics combined with implant repair on the aesthetic effect and gingival crevicular fluid factor of patients with dentition defect and periodontitis, 60 patients who met the diagnostic criteria of chronic periodontitis were proposed. They were randomly divided into treatment group (taking Bushen Huoxue Guchi recipe for 3 courses while basic periodontal treatment) and control group (only basic periodontal treatment without taking any drugs). The experimental method of 30 cases in each group showed that PD, Al, and GI in the treatment group and control group

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Faot, Fernanda, Amália Machado Bielemann, Alessandra Julie Schuster, et al. "Influence of Insertion Torque on Clinical and Biological Outcomes before and after Loading of Mandibular Implant-Retained Overdentures in Atrophic Edentulous Mandibles." BioMed Research International 2019 (June 2, 2019): 1–14. http://dx.doi.org/10.1155/2019/8132520.

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Aim. To evaluate the influence of primary insertion torque (IT) values of narrow dental implants on the peri-implant health, implant stability, immunoinflammatory responses, bone loss, and success and survival rates. Methods. Thirty-one edentulous patients received two narrow implants (2.9x10mm, Facility NeoPoros) to retain mandibular overdentures. The implants were categorized in four groups according to their IT: (G1) IT > 10 Ncm; (G2) IT ≥ 10Ncm and ≤ 30 Ncm; (G3) IT >30Ncm and < 45Ncm; (G4) IT ≥ 45Ncm, and all implants were loaded after 3 months of healing. The following clinical

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Yaghobee, Siamak, Afshin Khorsand, Nojan Jahedmanesh, and Mahdi Kadkhodazadeh. "Assessment of Aggregatibacter actinomycetemcomitans and Prevotella intermedia Counts around Healthy Implants, Diseased Implants and Sound Teeth: A Preliminary Study." Journal of Periodontology & Implant Dentistry 9, no. 1 (2017): 18–25. http://dx.doi.org/10.15171/jpid.2017.004.

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Background. This study aimed to assess Aggregatibacter actinomycetemcomitans (Aa) and Prevotella intermedia (PI) counts in gingival crevicular fluid (GCF) around healthy implants, diseased implants and sound teeth. Methods. Eight patients (four males and four females), who had healthy implants, implants with peri-implantitis and sound teeth, were selected. Samples (GCF) were analyzed using real-time polymerase chain reaction (RT-PCR). The above-mentioned bacteria were detected and counted. Data analysis in RT-PCR was carried out based on the standard curve using Prism software to compare Pi an

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Ramírez Thomé, Saira, Beatriz Ávila Curiel, María T. Hernández Huerta та Carlos Solórzano Mata. "β-defensinas como posibles indicadores de la actividad inflamatoria en la enfermedad periodontal." Investigación Clínica 63, № 4 (2022): 414–34. http://dx.doi.org/10.54817/ic.v63n4a08.

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Periodontal disease (gingivitis and periodontitis) is an inflam-matory process caused by the activity of pathogenic bacteria and their products on the gingival sulcus, with the consequent activation of the immune response. Saliva and crevicular fluid contain a wide variety of enzymes and antimicrobial factors that are in contact with the supragingival and subgingival region, in-cluding β-defensins (hBDs). hHBDs are non-glycosylated, cysteine-rich cationic peptides produced by epithelial cells with antimicrobial and immunoregulatory effects, thus contributing to maintaining homeostasis in perio

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Taymour, Noha, Mohamed G. Hassan, Maram A. AlGhamdi, and Wessam S. Omara. "From Detection to Treatment: Nanomaterial-Based Biosensors Transforming Prosthetic Dentistry and Oral Health Care: A Scoping Review." Prosthesis 7, no. 3 (2025): 51. https://doi.org/10.3390/prosthesis7030051.

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Background: Nanomaterial-based biosensors represent a transformative advancement in oral health diagnostics and therapeutics, offering superior sensitivity and selectivity for early disease detection compared to conventional methods. Their applications span prosthetic dentistry, where they enable the precise monitoring of dental implants, and theranostics for conditions such as dental caries, oral cancers, and periodontal diseases. These innovations promise to enhance proactive oral healthcare by integrating detection, treatment, and preventive strategies. Objectives: This review comprehensive

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Celebi, Ahmet Arif, Serhat Demirer, Bulent Catalbas та Sevket Arikan. "Effect of ovarian activity on orthodontic tooth movement and gingival crevicular fluid levels of interleukin-1β and prostaglandin E2 in cats". Angle Orthodontist 83, № 1 (2012): 70–75. http://dx.doi.org/10.2319/012912-78.1.

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Abstract Objective: To evaluate whether there is any correlation between ovarian activity and two potent bone-resorbing mediators (prostaglandin E2 [PGE2], interleukin-1β [IL-1β]) secreted from the gingival crevicular fluid (GCF) during orthodontic tooth movement. Materials and Methods: Eighteen female cats were included in this study. Animals were randomly divided into three groups (estrous, anestrous, and ovariectomized groups), each having six queens. Estrous was induced by administration of 150 IU equine chorionic gonadotropin (eCG) to queens of the estrous group. A closed-coil spring, app

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Sharma, Vineet, Supriya Nambiar, Poornima Manjrekar, Asavari Desai, and Pramod Philip. "Assessment of Myeloperoxidase Levels In Relation to the Nature and Duration of Orthodontic Forces – An In vivo, Split Mouth Study." Biomedical and Pharmacology Journal 11, no. 4 (2018): 2061–67. http://dx.doi.org/10.13005/bpj/1583.

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To assess the change in the myeloperoxidase levels(MPO)in the gingival crevicular fluid(GCF) at different time intervals during the course of orthodontic treatment with the application of intermittent and continuous forces. It was an interventional, split mouth study done on twenty patients scheduled to undergo fixed orthodontic treatment with therapeutic extractions of the first premolars.Mini implant assisted enmasse retraction was done after leveling and aligning of the arch.Continuous force with the help of Niti coil spring was used in the first quadrant and intermittent force with an elas

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Hou, X., L. Wang, S. Fan, J. Yang, Q. Liu, and F. Wang. "Expression Level and Clinical Significance of Inflammatory Cytokines and Biochemical Markers in Gingival Crevicular Fluid During Different Crown Adhesion Patterns of Dental Implant." Nigerian Journal of Clinical Practice 24, no. 8 (2021): 1181. http://dx.doi.org/10.4103/njcp.njcp_152_20.

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International, BioMed Research. "Retracted: Effect of Orthodontic Combined with Implant Repair on Aesthetic Effect and Gingival Crevicular Fluid Factor in Patients with Dentition Defect and Periodontitis." BioMed Research International 2023 (July 12, 2023): 1. http://dx.doi.org/10.1155/2023/9807383.

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Wei, Zhili, and Li Wei. "Application of Zirconia Ceramic Biomaterial Implants in the Restoration of Tooth Loss Caused by Periodontal Disease." Science of Advanced Materials 14, no. 1 (2022): 1–10. http://dx.doi.org/10.1166/sam.2022.4173.

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Zirconia ceramics (ZiC) has become a biomaterial with good clinical application prospects due to its good biocompatibility, stability, and excellent mechanical properties. In this study, bioactive glass (BioS) was undertaken as the modifier, and the ZiC precursor solution was penetrated on the surface of the ZiC body or the ZiC particles were coated with the BioS precursor solution, so as to obtain the ZiC with biological activity by introducing the BioS phase. While the material was characterized, its mechanical properties and biological activity were analyzed by simulating the mineralization

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Pan, Taohua, Shuo Liu, Qingqing Liu, Minyi Zhang, and Lilei Zhu. "Effect of Glycine Subgingival Sandblasting on the Incidence of Peri-Implantitis and Expression of Inflammatory Factors in Gingival Crevicular Fluid in Patients with Titanium-Nickel-Chromium Alloy Porcelain-Fused-To-Metal Crowns." Science of Advanced Materials 16, no. 3 (2024): 396–403. http://dx.doi.org/10.1166/sam.2024.4611.

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This research was aimed to demonstrate impacts of glycine subgingival sandblasting on peri-implantitis (PI), periodontal clinical parameters, and inflammatory factor expression in gingival crevicular fluid (GCF) in patients with titanium-nickel-chromium (TiNiCr) alloy porcelain-fused-to-metal crown (APC) restorations. A total of 159 patients with TiNiCr APCs were randomly rolled into glycine subgingival sandblasting group (Exp 1 group), erythritol subgingival sandblasting group (Exp 2 group), and conventional scaling and root planing (SRP) treatment group (Con group), with 53 patients in each

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Arıkan, Fatih, Nurcan Buduneli, and Necil Kütükçüler. "Osteoprotegerin levels in peri-implant crevicular fluid." Clinical Oral Implants Research 19, no. 3 (2008): 283–88. http://dx.doi.org/10.1111/j.1600-0501.2007.01463.x.

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