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Journal articles on the topic 'Ginseng'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Zhang, Wen-Song, An Pan, Liu Yang, et al. "American Ginseng and Asian Ginseng Intervention in Diet-Induced Obese Mice: Metabolomics Reveals Distinct Metabolic Profiles." American Journal of Chinese Medicine 47, no. 04 (2019): 787–801. http://dx.doi.org/10.1142/s0192415x19500411.

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American ginseng and Asian ginseng, which occupy prominent positions in the list of best-selling natural products in the West and East, are suitable for different indications in the traditional pharmacological uses. Currently, the effects of American ginseng and Asian ginseng in the protection against metabolic dysfunction and the differences between them are still unknown. Herein, an untargeted metabolomics based on liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS) was determined. The serum metabolomics and dynamic feces metabolomics revealed significant metaboli

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2

Wu, Tao, Osafo Raymond Kwaku, Hai-Zhou Li, Chong-Ren Yang, Long-Jiao Ge, and Min Xu. "Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy." Natural Product Communications 14, no. 6 (2019): 1934578X1985822. http://dx.doi.org/10.1177/1934578x19858223.

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The term ginseng refers to the dried roots of several plants belonging to the genus Panax of the Araliaceae family. The 3 major commercial ginsengs are Panax notoginseng (Burk.) F.H. Chen (Notoginseng), P. ginseng C.A. Meyer (Ginseng), and P. quinquefolius L. (American ginseng), which have been used as herbal medicines. Over 18,000 papers on ginsengs have been published on the basis of their structural diversity and biological activities. Many reviews have summarized the phytochemistry, pharmacology, and clinical use of ginsengs, but the structure-activity relationship (SAR) of ginsenosides fr

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3

Zhang, Meng, Yingxin Sun, Zeliang Lv, Hongmei Lin, Mei Han, and Limin Yang. "The Adaptive Mechanism of Ginseng Rhizomes in Response to Habitat Changes." Current Issues in Molecular Biology 46, no. 11 (2024): 12260–78. http://dx.doi.org/10.3390/cimb46110728.

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Panax ginseng, a perennial medicinal plant, utilizes its dried roots and rhizomes for medicinal purposes. Currently, in China, ginseng cultivation employs two methods: under-forest and farmland planting. These methods create distinct habitats, significantly influencing the ginseng’s rhizome morphology and, consequently, its economic value. In this study, two-year-old ginsengs were transplanted into farmland (TCG), a larch forest (TLCG) and a Quercus mongolica forest (TQCG) to analyze the differences in rhizome phenotypes caused by habitat changes. The results showed that there were significant

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4

Sun, Yizheng, Xiaoyan Liu, Xiaojie Fu, Wei Xu, Qingmei Guo, and Youbo Zhang. "Discrepancy Study of the Chemical Constituents of Panax Ginseng from Different Growth Environments with UPLC-MS-Based Metabolomics Strategy." Molecules 28, no. 7 (2023): 2928. http://dx.doi.org/10.3390/molecules28072928.

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Panax ginseng (P. ginseng), the dried root and rhizome of P. ginseng C. A. Meyer, is widely used in many fields as dietary supplements and medicine. To characterize the chemical constituents in P. ginseng cultivated in different growth environments, a UPLC-TOF-MS method was established for qualitative analysis. Four hundred and eight ginsenosides, including 81 new compounds, were characterized in P. ginseng from different regions. Among the detected compounds, 361 ginsenosides were recognized in P. ginseng cultivated in the region of Monsoon Climate of Medium Latitudes, possessing the largest

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5

Yoon, Dahye, Woo Cheol Shin, Young-Seob Lee, Suhkmann Kim, Nam-In Baek, and Dae Young Lee. "A Comparative Study on Processed Panax ginseng Products Using HR-MAS NMR-Based Metabolomics." Molecules 25, no. 6 (2020): 1390. http://dx.doi.org/10.3390/molecules25061390.

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Panax ginseng is processed to diversify efficacy. Four processed ginsengs containing white ginseng (WG), tae-geuk ginseng (TG), red ginseng (RG), and black ginseng (BG) were analyzed using nuclear magnetic resonance (NMR) spectroscopy for screening overall primary metabolites. There were significant differences in the sugar content among these four processed ginseng products. WG had a high sucrose content, TG had a high maltose content, and BG had high fructose and glucose content. In the multivariate analyses of NMR spectra, the PCA score plot showed significant discrimination between the fou

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6

Goodwin, Paul H., and Madison A. Best. "Ginsenosides and Biotic Stress Responses of Ginseng." Plants 12, no. 5 (2023): 1091. http://dx.doi.org/10.3390/plants12051091.

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Ginsenosides are saponins that possess a sugar moiety attached to a hydrophobic aglycone triterpenoid. They have been widely studied for their various medicinal benefits, such as their neuroprotective and anti-cancer activities, but their role in the biology of ginseng plants has been much less widely documented. In the wild, ginsengs are slow-growing perennials with roots that can survive for approximately 30 years; thus, they need to defend themselves against many potential biotic stresses over many decades. Biotic stresses would be a major natural selection pressure and may at least partial

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7

Cương, Lê Kim, Nguyễn Hồng Hoàng, and Dương Tấn Nhựt. "Effect of some factors on the growth and regeneration of cell suspension of Ngoc Linh ginseng (Panax vietnamensis Ha et Grushv.)." Vietnam Journal of Biotechnology 14, no. 1 (2016): 75–86. http://dx.doi.org/10.15625/1811-4989/14/1/9295.

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Ngoc Linh ginseng also known as Vietnamese ginseng (Panax Vietnamensis Ha et Grushv.) is a perennial medicinal plant. This plant is extremely rare and belongs to the Araliaceae family. Scientists are focusing on studies of Ngoc Linh ginseng nowadays. In this research, the effects of 2,4-dichlorophenoxyacetic acid (2,4-D), a-naphthaleneacetic acid (NAA), indole-3-butyric acid (IBA), 6-benzylaminopurine (BA), Kinetin (KIN), mineral salt formulations and cultural conditions, pH, sucrose concentration, medium volume on cell suspension culture of Panax vietnamensis Ha et Grushv. were investigated.

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8

Li, Jinying, Jianlei Qiao, Chang Liu, et al. "Study on the Geographic Traceability and Growth Age of Panax ginseng C. A. Meyer Base on an Electronic Nose and Fourier Infrared Spectroscopy." Chemosensors 13, no. 5 (2025): 176. https://doi.org/10.3390/chemosensors13050176.

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During ginseng selection, marketing promotion, and sales, it is imperative to expeditiously differentiate the overall quality grades, identify the geographic traces and determine the growth ages. This facilitates the selection of the most appropriate quality grade for each product, thereby ensuring the most efficacious marketing strategy. In this study, a new method is proposed and developed for the classification of ginsengs with diverse geographical traceability and with various growth ages by combining an electronic nose (E-nose) system and machine learning with Fourier-transform infrared s

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9

Pfuhlmann, Katrin, Petra Klose, Tanja Neufeld, and Jost Langhorst. "Ginseng – die Möglichkeit seiner Anwendung zur Behandlung der Tumor-assoziierten Müdigkeit." Zeitschrift für Phytotherapie 43, no. 02 (2022): 56–61. http://dx.doi.org/10.1055/a-1811-2811.

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ZUSAMMENFASSUNGVon dem zu den Efeugewächsen gehörigen Ginseng sind vor allem zwei Arten bekannt: Der Asiatische oder Koreanische Ginseng Panax ginseng und der Amerikanische Ginseng Panax quinquefolius. Anwendung finden Verarbeitungen der Ginsengwurzel (Ginseng Radix), welche etliche gesundheitsförderliche Inhaltsstoffe enthält. Die wichtigsten pharmakologisch aktiven Substanzen stellen die Ginsenoside dar. Ginseng gilt als traditionelles Mittel gegen Erschöpfungszustände aller Art. Für diesen Zweck ist der Asiatische Ginseng in Europa als Arzneimittel zugelassen. Ergebnisse hochwertiger random

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Pfuhlmann, Katrin, Petra Klose, Tanja Neufeld, and Jost Langhorst. "Ginseng – die Möglichkeit seiner Anwendung zur Behandlung der Tumor-assoziierten Müdigkeit." Zeitschrift für Phytotherapie 43, no. 02 (2022): 56–61. http://dx.doi.org/10.1055/a-1811-2811.

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ZUSAMMENFASSUNGVon dem zu den Efeugewächsen gehörigen Ginseng sind vor allem zwei Arten bekannt: Der Asiatische oder Koreanische Ginseng Panax ginseng und der Amerikanische Ginseng Panax quinquefolius. Anwendung finden Verarbeitungen der Ginsengwurzel (Ginseng Radix), welche etliche gesundheitsförderliche Inhaltsstoffe enthält. Die wichtigsten pharmakologisch aktiven Substanzen stellen die Ginsenoside dar. Ginseng gilt als traditionelles Mittel gegen Erschöpfungszustände aller Art. Für diesen Zweck ist der Asiatische Ginseng in Europa als Arzneimittel zugelassen. Ergebnisse hochwertiger random

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Pfuhlmann, Katrin, Petra Klose, Tanja Neufeld, and Jost Langhorst. "Ginseng – die Möglichkeit seiner Anwendung zur Behandlung der Tumor-assoziierten Müdigkeit." Deutsche Zeitschrift für Onkologie 53, no. 02 (2021): 69–73. http://dx.doi.org/10.1055/a-1479-8057.

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ZUSAMMENFASSUNGVon dem zu den Efeugewächsen gehörigen Ginseng sind vor allem zwei Arten bekannt: Der Asiatische oder Koreanische Ginseng Panax ginseng und der Amerikanische Ginseng Panax quinquefolius. Anwendung finden Verarbeitungen der Ginsengwurzel (Ginseng Radix), welche etliche gesundheitsförderliche Inhaltsstoffe enthält. Die wichtigsten pharmakologisch aktiven Substanzen stellen die Ginsenoside dar. Ginseng gilt als traditionelles Mittel gegen Erschöpfungszustände aller Art. Für diesen Zweck ist der Asiatische Ginseng in Europa als Arzneimittel zugelassen. Ergebnisse hochwertiger random

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12

Liu, Zhihao, Roderick Moore, Ying Gao, et al. "Comparison of Phytochemical Profiles of Wild and Cultivated American Ginseng Using Metabolomics by Ultra-High Performance Liquid Chromatography-High-Resolution Mass Spectrometry." Molecules 28, no. 1 (2022): 9. http://dx.doi.org/10.3390/molecules28010009.

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American ginseng (Panax quinquefolius L.) has been recognized as a valuable herb medicine, and ginsenosides are the most important components responsible for the health-beneficial effects. This study investigated the secondary metabolites responsible for the differentiation of wild and cultivated American ginsengs with ultrahigh-performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS)-based metabolomic approach. An in-house ginsenoside library was developed to facilitate data processing and metabolite identification. Data visualization methods, such as heatmaps and volc

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13

Le, Quang-Ung, Horng-Liang Lay, Ming-Chang Wu, Thi Hong-Hanh Nguyen, and Duy-Lam Nguyen. "Phytoconstituents and Biological Activities of Panax vietnamensis (Vietnamese Ginseng): A Precious Ginseng and Call for Further Research-A systematic review." Natural Product Communications 13, no. 10 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301036.

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Panax vietnamensis Ha et Grushv., a Vietnamese ginseng, is a well-known plant, naturally distributed in the Ngoc Linh and Hoang Lien Son mountain areas in Vietnam. It is used as a tonic and medicinal food in traditional folk medicine because it possesses wondrous health benefits. To support its functional attributes, various investigations have been carried out to find out its anti-inflammatory, anti-cancer, anti-stress, anti-nociception, psychomotor and sedative-hypnotic effects and anxiolytic activities. Also similar to other ginsengs, Vietnamese ginseng is a rich source of saponins and it h

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14

Chen, Wei, Prabhu Balan, and David G. Popovich. "Comparison of Ginsenoside Components of Various Tissues of New Zealand Forest-Grown Asian Ginseng (Panax Ginseng) and American Ginseng (Panax Quinquefolium L.)." Biomolecules 10, no. 3 (2020): 372. http://dx.doi.org/10.3390/biom10030372.

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Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolium L.) are the two most important ginseng species for their medicinal properties. Ginseng is not only popular to consume, but is also increasingly popular to cultivate. In the North Island of New Zealand, Asian ginseng and American ginseng have been grown in Taupo and Rotorua for more than 15 years. There are no publications comparing the chemical constituents between New Zealand-grown Asian ginseng (NZPG) and New Zealand-grown American ginseng (NZPQ). In this study, fourteen ginsenoside reference standards and LC–MS2 technol

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15

Yoo, Hye Hyun, Takako Yokozawa, Akiko Satoh, Ki Sung Kang, and Hyun Young Kim. "Effects of Ginseng on the Proliferation of Human Lung Fibroblasts." American Journal of Chinese Medicine 34, no. 01 (2006): 137–46. http://dx.doi.org/10.1142/s0192415x06003709.

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In this study, we investigated the effects of methanolic extracts of white ginseng (Panax ginseng C.A. MEYER) and two kinds of heat-treated ginseng made by steaming fresh ginseng at 100°C for 3 hours (HTG-100) or 120°C for 3 hours (HTG-120) on the cell growth of human fibroblasts. All of the tested ginseng extracts stimulated cell growth, although the effect of HTG-120 was weaker than that of the other extracts. However, none of the ginseng extracts exhibited any effect on the growth of old cells with a population doubling level (PDL) of 48.7. Flow cytometric analysis showed that ginseng extra

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16

Han, Myung Joo, and Dong-Hyun Kim. "Effects of Red and Fermented Ginseng and Ginsenosides on Allergic Disorders." Biomolecules 10, no. 4 (2020): 634. http://dx.doi.org/10.3390/biom10040634.

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Both white ginseng (WG, dried root of Panax sp.) and red ginseng (RG, steamed and dried root of Panax sp.) are reported to exhibit a variety of pharmacological effects such as anticancer, antidiabetic, and neuroprotective activities. These ginsengs contain hydrophilic sugar-conjugated ginsenosides and polysaccharides as the bioactive constituents. When taken orally, their hydrophilic constituents are metabolized into hydrophobic ginsenosides compound K, Rh1, and Rh2 that are absorbable into the blood. These metabolites exhibit the pharmacological effects more strongly than hydrophilic parental

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17

Inagaki, Tetsuya, Norihisa Katayama, Rae-Kwang Cho, Xijun Chen, and Satoru Tsuchikawa. "Near infrared estimation of concentration of ginsenosides in Asian ginseng." Journal of Near Infrared Spectroscopy 27, no. 2 (2018): 115–22. http://dx.doi.org/10.1177/0967033518814851.

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In this study, the feasibility of near infrared reflectance spectroscopy for the quality evaluation of the main bioactive compounds, ginsenosides, in Panax ginseng was examined. Second derivative NIR spectra of standard reagents of ginsenoside Rg1, Re, Rb1, Rc, Rb2 and Rd were used for analysis. Characteristic bands were observed at around 5250 cm−1 in the spectra of ginsenoside Rg1 group (including Rg1 and Re); however, this was not to be observed on the spectra of ginsenoside Rb1 group (including Rb1, Rc, Rb2 and Rd). PLS regression models were constructed of air-dry ginseng powder samples a

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Chen, Wei, Prabhu Balan, and David G. Popovich. "Changes of Ginsenoside Composition in the Creation of Black Ginseng Leaf." Molecules 25, no. 12 (2020): 2809. http://dx.doi.org/10.3390/molecules25122809.

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Ginseng is an increasingly popular ingredient in supplements for healthcare products and traditional medicine. Heat-processed ginsengs, such as red ginseng or black ginseng, are regarded as more valuable for medicinal use when compared to white ginseng due to some unique less polar ginsenosides that are produced during heat-treatment. Although ginseng leaf contains abundant ginsenosides, attention has mostly focused on ginseng root; relatively few publications have focused on ginseng leaf. Raw ginseng leaf was steamed nine times to make black ginseng leaf using a process that is similar to tha

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Wang, Chong-Zhi, and Chun-Su Yuan. "Potential Role of Ginseng in the Treatment of Colorectal Cancer." American Journal of Chinese Medicine 36, no. 06 (2008): 1019–28. http://dx.doi.org/10.1142/s0192415x08006545.

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Colorectal cancer remains one of the most prevalent cancer and a leading cause of cancer related death in the US. Many currently used chemotherapeutic agents are derived from botanicals. Identifying herbal sources, including those from ginseng family, to develop better anti-cancer therapies remains an essential step in advancing the treatment of the cancer. In this article, potential roles of ginseng herbs, especially American ginseng and notoginseng, in colorectal cancer therapeutics are presented. The major pharmacologically active constituents of ginsengs are ginsenosides, which can be main

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Kandpal, Lalit Mohan, Jayoung Lee, Hyungjin Bae, Moon S. Kim, Insuck Baek, and Byoung-Kwan Cho. "Near-Infrared Transmittance Spectral Imaging for Nondestructive Measurement of Internal Disorder in Korean Ginseng." Sensors 20, no. 1 (2020): 273. http://dx.doi.org/10.3390/s20010273.

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The grading of ginseng (Panax ginseng) including the evaluation of internal quality attributes is essential in the ginseng industry for quality control. Assessment for inner whitening, a major internal disorder, must be conducted when identifying high quality ginseng. Conventional methods for detecting inner whitening in ginseng root samples use manual inspection, which is time-consuming and inaccurate. This study develops an internal quality measurement technique using near-infrared transmittance spectral imaging to evaluate inner whitening in ginseng samples. Principle component analysis (PC

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Nguyen, Ngoc, Trieu Nguyen, Phu Le Hong, et al. "Application of Coating Chitosan Derivatives (N,O–Carboxymethyl Chitosan/Chitosan Oligomer Saccharide) in Combination with Polyvinyl Alcohol Solutions to Preserve Fresh Ngoc Linh Ginseng Quality." Foods 12, no. 21 (2023): 4012. http://dx.doi.org/10.3390/foods12214012.

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The postharvest preservation of Ngoc Linh ginseng (NL ginseng) is essential to retain its quality and sensory values for prolonged storage. In this study, the efficacy of NL ginseng preservation by coating chitosan derivatives in combination with polyvinyl alcohol (PVA) solutions was investigated under refrigeration conditions (~3 °C; ~40% RH) for 56 days. The effect of the chitosan–based solutions, including N,O–carboxymethyl chitosan (NOCC), chitosan oligomer saccharide (COS), or chitosan (CS), and the blend solutions (NOCC–PVA or COS–PVA) on the coated NL ginsengs was observed during storag

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Zhang, Chi, Zhe Liu, Shaoming Lu, et al. "Rapid Discrimination and Prediction of Ginsengs from Three Origins Based on UHPLC-Q-TOF-MS Combined with SVM." Molecules 27, no. 13 (2022): 4225. http://dx.doi.org/10.3390/molecules27134225.

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Ginseng, which contains abundant ginsenosides, grows mainly in the Jilin, Liaoning, and Heilongjiang in China. It has been reported that the quality and traits of ginsengs from different origins were greatly different. To date, the accurate prediction of the origins of ginseng samples is still a challenge. Here, we integrated ultra-high-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) with a support vector machine (SVM) for rapid discrimination and prediction of ginseng from the three main regions where it is cultivated in China. Firstly, we develo

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Lin, Jia-Wei, Yih-Giun Cherng, Li-Jen Chen, Ho-Shan Niu, Chen Kuei Chang, and Chiang-Shan Niu. "Ginseng Is Useful to Enhance Cardiac Contractility in Animals." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/723084.

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Ginseng has been shown to be effective on cardiac dysfunction. Recent evidence has highlighted the mediation of peroxisome proliferator-activated receptors (PPARs) in cardiac function. Thus, we are interested to investigate the role of PPARδin ginseng-induced modification of cardiac contractility. The isolated hearts in Langendorff apparatus and hemodynamic analysis in catheterized rats were applied to measure the actions of ginsengex vivoandin vivo. In normal rats, ginseng enhanced cardiac contractility and hemodynamicdP/dtmaxsignificantly. Both actions were diminished by GSK0660 at a dose en

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Luo, John Zeqi, and Luguang Luo. "Ginseng on Hyperglycemia: Effects and Mechanisms." Evidence-Based Complementary and Alternative Medicine 6, no. 4 (2009): 423–27. http://dx.doi.org/10.1093/ecam/nem178.

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It has been reported that American ginseng attenuates hyperglycemia and may present itself as a supplement to diabetes therapy. However, the lack of standardization in the usage of ginseng root leads to inconclusive results when applied to diabetes treatment. The mechanisms of American ginseng root in the treatment of diabetes remains a mystery. This greatly limits the effective utilization of American ginseng in facilitating diabetic therapy. Initiating studies have shown that American ginseng increases insulin production and reduces cell death in pancreatic β-cells. Also, studies have reveal

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Chen, Wei, Prabhu Balan, and David G. Popovich. "Review of Ginseng Anti-Diabetic Studies." Molecules 24, no. 24 (2019): 4501. http://dx.doi.org/10.3390/molecules24244501.

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Ginseng is one of the most valuable and commonly used Chinese medicines not only in ancient China but also worldwide. Ginsenosides, also known as saponins or triterpenoids, are thought to be responsible for the beneficial effects of ginseng. In this review, we summarize recent publications on anti-diabetic studies of ginseng extracts and ginsenosides in cells, animals, and humans. It seems that the anti-diabetic effect of ginseng is positive for type 2 diabetic patients but has no significant impact on prediabetes or healthy adults. Regulation of insulin secretion, glucose uptake, anti-oxidati

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Yip, T. T., C. N. B. Lau, P. P. H. But, and Y. C. Kong. "Quantitative Analysis of Ginsenosides in Fresh Panax Ginseng." American Journal of Chinese Medicine 13, no. 01n04 (1985): 77–88. http://dx.doi.org/10.1142/s0192415x85000125.

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TLC, DCC and HPLC were used to study the ginsenoside composition of the main root, lateral root, rhizomem leaves and seeds of Panax ginseng cultivated in Jilin, China. Each of these methods has advantages of its own and the ensemble reveal the special features of Jilin ginseng. Total saponin content of various plant parts in Jilin ginseng showed a mid-range value as compared to those in ginsengs reported in literature. Fresh as well as sun-dried specimens from the same batch possessed a high percentage of Rg1 in the main root and this might account for the traditional preference of this plant

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Dasgupta, Amitava, Edward Kang, Margaret Olsen, Jeffrey K. Actor, and Pradip Datta. "Interference of Asian, American, and Indian (Ashwagandha) Ginsengs in Serum Digoxin Measurements by a Fluorescence Polarization Immunoassay Can Be Minimized by Using a New Enzyme-Linked Chemiluminescent Immunosorbent or Turbidimetric Assay." Archives of Pathology & Laboratory Medicine 131, no. 4 (2007): 619–21. http://dx.doi.org/10.5858/2007-131-619-ioaaai.

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Abstract Context.—Ginsengs are widely used by the general population. These herbs interfere with serum digoxin measurement using the fluorescence polarization immunoassay. Objective.—To assess potential interference of different ginsengs (Asian, American, and Indian, also known as Ashwagandha) in vitro and in vivo in a mouse model by using a new enzyme-linked chemiluminescent immunosorbent digoxin assay and an existing turbidimetric assay. Comparisons were made with the fluorescence polarization immunoassay. Design.—Aliquots of drug-free serum pools were supplemented with ginseng and apparent

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Wang, Yabo, and Xinxin Liu. "The Effective Components, Core Targets, and Key Pathways of Ginseng against Alzheimer’s Disease." Evidence-Based Complementary and Alternative Medicine 2023 (January 23, 2023): 1–12. http://dx.doi.org/10.1155/2023/9935942.

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Background. Panax ginseng C. A. Mey (ginseng) is a traditional Chinese medicinal herb used for the treatment of nervous system disorders, such as Alzheimer’s disease (AD). However, the pharmacological mechanisms of ginseng involved in AD have not been systematically investigated. Here, a network pharmacology approach was adopted to explore the effective components, core targets, and key pathways of ginseng against AD. Methods. TCMSP database was used to screen the active ingredients of ginseng. Prediction of the targets of ginseng and AD-related genes was performed using online public database

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Reshetnikov, V. N., H. G. Shutava, S. N. Shysh та T. V. Gil. "Influence of various factors on the antiradical activity of Panax ginseng С. A. Meyer extracts". Faktori eksperimental'noi evolucii organizmiv 23 (9 вересня 2018): 329–33. http://dx.doi.org/10.7124/feeo.v23.1036.

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Aim. The aim of the work was to evaluate the anti-radical activity of extracts of ginseng's underground and overground organs Panax ginseng C.A. Mey, depending on various factors – age of plants, collection time and cultivation conditions. Methods. Extracts obtained from various plant organs were evaluated in the model system with cation-radicals ABTS. At the same time, the amount of extractive substances and phenolic compounds was determined. Results. Samples of leaves and roots of ginseng of 1, 2, 3, 5, 9 years of vegetation from the collection of the Central Botanical Garden of the National

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Yu, Yinan, Jingzi Piao, Siyi Guo, Bing Li, Zibo Li, and Rujun Zhou. "Evaluation of Rain Shelter Cultivation Mode Effects on Microecological Environment of Mountain Cultivated Ginseng Rhizosphere." Agronomy 14, no. 11 (2024): 2590. http://dx.doi.org/10.3390/agronomy14112590.

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Rainfall, particularly in continental climates with a monsoonal tendency, impacts the microbial niches during the growth of mountain cultivated ginseng. With shifts in the microbial community, diseases in ginseng cultivated and protected under rain shelter conditions may ultimately be altered. Such cultivation may influence microflora dynamics through variations in meteorological parameters; however, this is not yet clear. The present study found that rain shelter cultivation affected the distribution of fungal communities within mountain cultivated ginseng. This led to an improved community s

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Alsayari, Abdulrhman, Abdullatif Bin Muhsinah, Dalia Almaghaslah, Sivakumar Annadurai, and Shadma Wahab. "Pharmacological Efficacy of Ginseng against Respiratory Tract Infections." Molecules 26, no. 13 (2021): 4095. http://dx.doi.org/10.3390/molecules26134095.

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Respiratory tract infections are underestimated, as they are mild and generally not incapacitating. In clinical medicine, however, these infections are considered a prevalent problem. By 2030, the third most comprehensive reason for death worldwide will be chronic obstructive pulmonary disease (COPD), according to the World Health Organization. The current arsenal of anti-inflammatory drugs shows little or no benefits against COPD. For thousands of years, herbal drugs have been used to cure numerous illnesses; they exhibit promising results and enhance physical performance. Ginseng is one such

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Zhang, Meng, Huazhou Niu, Qingqing Li, Lili Jiao, Hui Li, and Wei Wu. "Active Compounds of Panax ginseng in the Improvement of Alzheimer’s Disease and Application of Spatial Metabolomics." Pharmaceuticals 17, no. 1 (2023): 38. http://dx.doi.org/10.3390/ph17010038.

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Panax ginseng C.A. Meyer (P. ginseng) is one of the more common traditional Chinese medicines (TCMs). It contains numerous chemical components and exhibits a range of pharmacological effects. An enormous burden is placed on people’s health and life by Alzheimer’s disease (AD), a neurodegenerative condition. Recent research has shown that P. ginseng’s chemical constituents, particularly ginsenosides, have a significant beneficial impact on the prevention and management of neurological disorders. To understand the current status of research on P. ginseng to improve AD, this paper discusses the c

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Li, Shaokun, Li Li, Yang Jiang, et al. "SQUAMOSA Promoter Binding Protein-Like (SPL) Gene Family: TRANSCRIPTOME-Wide Identification, Phylogenetic Relationship, Expression Patterns and Network Interaction Analysis in Panax ginseng C. A. Meyer." Plants 9, no. 3 (2020): 354. http://dx.doi.org/10.3390/plants9030354.

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SPL (SQUAMOSA promoter binding protein-like) gene family is specific transcription factor in the plant that have an important function for plant growth and development. Although the SPL gene family has been widely studied and reported in many various plant species from gymnosperm to angiosperm, there are no systematic studies and reports about the SPL gene family in Panax ginseng C. A. Meyer. In this study, we conducted transcriptome-wide identification, evolutionary analysis, structure analysis, and expression characteristics analysis of SPL gene family in Panax ginseng by bioinformatics. We

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Aielli, Lisa, Chman Shahzadi, and Erica Costantini. "Exploring ginseng's potential role as an adjuvant therapy in COVID-19." AIMS Allergy and Immunology 7, no. 4 (2023): 251–72. http://dx.doi.org/10.3934/allergy.2023017.

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<abstract> <p>Ginseng is a plant from the Panax genus used since ancient times as a prominent component of traditional Chinese medicine, and is prized for its energizing, antiaging and antioxidant properties. Over time, the scientific community has taken a keen interest in ginseng's potential as a supplement in various health sectors. While there is a substantial body of data demonstrating the effectiveness of ginseng and other natural products as adjuncts in the treatment of respiratory diseases, the emergence of the COVID-19 pandemic has amplified the attention on ginseng and its

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Dong, Tai Thi Ngoc, Chih-Hsiung Lin, and Ming-Tsai Liang. "The Application of Simulated Moving-Bed Chromatography for the Separation of Ginsenosides in Sanchi Ginseng and American Ginseng." Natural Product Communications 15, no. 10 (2020): 1934578X2096467. http://dx.doi.org/10.1177/1934578x20964671.

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In this study, the separation of ginsenosides from the crude extract of Sanchi ginseng and American ginseng, obtained by aqueous ethanol extraction, was conducted in a simulated moving bed (SMB) with cleaning in place (CIP) design. Concentrated products with 86.2%, w/w, and 91.5%, w/w, of ginsenosides were obtained by the utilization of CIP-SMB for Sanchi and American ginseng, respectively. This study reveals that CIP-SMB could enrich ginsenosides by removing the retained impurities, which were initially extracted by aqueous ethanol and not removed by either the antisolvent precipitation for S

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Xiang, Yun, Manshu Zou, Feilin Ou, et al. "A Comparison of the Impacts of Different Drying Methods on the Volatile Organic Compounds in Ginseng." Molecules 29, no. 22 (2024): 5235. http://dx.doi.org/10.3390/molecules29225235.

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Ginseng (Panax ginseng C. A. Meyer) is a valuable plant resource which has been used for centuries as both food and traditional Chinese medicine. It is popular in health research and markets globally. Fresh ginseng has a high moisture content and is prone to mold and rot, reducing its nutritional value without proper preservation. Drying treatments are effective for maintaining the beneficial properties of ginseng post-harvest. In this study, we investigated the effects of natural air drying (ND), hot-air drying (HAD), vacuum drying (VD), microwave vacuum drying (MVD), and vacuum freeze drying

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Kimura, Yoshiyuki, Maho Sumiyoshi, and Masahiro Sakanaka. "Effects of GinsenosideRb1on Skin Changes." Journal of Biomedicine and Biotechnology 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/946242.

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Ginseng roots (Panax ginsengCA Meyer) have been used traditionally for the treatment, especially prevention, of various diseases in China, Korea, and Japan. Both experimental and clinical studies suggest ginseng roots to have pharmacological effects in patients with life-style-related diseases such as non-insulin-dependent diabetic mellitus, atherosclerosis, hyperlipidemia, and hypertension. The topical use of ginseng roots to treat skin complaints including atopic suppurative dermatitis, wounds, and inflammation is also described in ancient Chinese texts; however, there have been relatively f

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Belanger, Danyka, Michele D. Calder, Alessandra Gianetto-Berruti, Edmund M. Lui, Andrew J. Watson, and Valter Feyles. "Effects of American Ginseng on Preimplantation Development and Pregnancy in Mice." American Journal of Chinese Medicine 44, no. 05 (2016): 981–95. http://dx.doi.org/10.1142/s0192415x16500543.

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In North America, a high proportion of pregnant women use herbal medications including North American ginseng. This medicinal plant contains high amounts of triterpene saponins (ginsenosides), which are the main bioactive compounds. It is important to assess ginseng’s impact on all reproductive functions to ensure the safety of pregnant women and fetuses. In this study, we defined the concentration-responsive effects of North American alcoholic and aqueous ginseng extracts on preimplantation development in vitro and on pregnancy and post-partum development in the mouse. Two-cell mouse embryos

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Choi, Woon-Yong, Choon-Geun Lee, Chi-Ho Song, et al. "Comparison of Low Molecular Ginsenoside Contents and CO2 Emission from Low Quality Fresh Ginseng by Low CO2 Emission Processes." Food Engineering Progress 16, no. 4 (2012): 325–32. http://dx.doi.org/10.13050/foodengprog.2012.16.4.325.

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This study is to demostrate how the low molecular ginsenosides can be produced from low grade fresh ginsengs by low CO2 emission processes. Since it was known to apply the low carbon dioxide emission processes to the ginseng processing companies due to requiring high temperature extractions in low grade fresh ginseng. Several types of low CO2 emission processes were empolyed in this experiment such as microwave, ultrasound, ultra-high pressure extraction process that can be more eaisly scaled up to ginseng processing industries. From microwave extraction process, 1.290 mg/g of total low molecu

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Piao, Xiang Min, Yue Huo, Jong Pyo Kang, et al. "Diversity of Ginsenoside Profiles Produced by Various Processing Technologies." Molecules 25, no. 19 (2020): 4390. http://dx.doi.org/10.3390/molecules25194390.

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Ginseng is a traditional medicinal herb commonly consumed world-wide owing to its unique family of saponins called ginsenosides. The absorption and bioavailability of ginsenosides mainly depend on an individual’s gastrointestinal bioconversion abilities. There is a need to improve ginseng processing to predictably increase the pharmacologically active of ginsenosides. Various types of ginseng, such as fresh, white, steamed, acid-processed, and fermented ginsengs, are available. The various ginseng processing methods produce a range ginsenoside compositions with diverse pharmacological properti

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Qiu, Fubin, Ying Huang, Lei Sun, Xiaoxia Zhang, Zhiheng Liu, and Wei Song. "Leifsonia ginsengi sp. nov., isolated from ginseng root." International Journal of Systematic and Evolutionary Microbiology 57, no. 2 (2007): 405–8. http://dx.doi.org/10.1099/ijs.0.64487-0.

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A Gram-positive, rod-shaped, non-motile bacterium, designated strain wged11T, was isolated from the root of ginseng, and its taxonomic position was established using a polyphasic approach. Phylogenetic analysis based on 16S rRNA gene sequences showed that this organism formed a robust clade with recognized species of the genus Leifsonia. Strain wged11T was characterized by a high content of ω-cyclohexylundecanoic and anteiso- and iso-branched saturated fatty acids, MK-11 as the major menaquinone and dl-2,4-diaminobutyric acid in its cell-wall peptidoglycan. The DNA G+C content of strain wged11

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Zhang, Qingxuan, Jialiang Liu, Yahui Liu, and Jie Du. "Meta-analysis of the Regulatory Effects of Ginseng and Ginseng-like Drugs on the Quality of Life and Immune Function of Cancer Patients." International Journal of Biology and Life Sciences 6, no. 2 (2024): 92–97. http://dx.doi.org/10.54097/y3jesv36.

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Objective To evaluate the regulatory effects of ginseng and ginseng-like drugs in improving the quality of life and immune function of cancer patients by meta-analysis. Methods Using "Ginseng", "Ginseng Decoction", "Ginsenosides", "Ginseng Polysaccharides", "Korean Ginseng", "Shanshen", "Shenqi Fuzheng Injection", "Kangai Injection", "Aidi Injection", "Ginseng Yangrong Soup" and "Buzhong Yiqi Soup" as Chinese keywords, "Ginseng", "Ginseng Soup", "Ginsenosides", "Ginseng Polysaccharides" as English keywords, the Chinese knowledge was retrieved.

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Grigoryev, Roman O., Nadezhda K, Chirikova, and Daniil N. Olennikov. "Qualitative and quantitative analysis of the content of phenolic compounds and their derivatives in the rhizome of Panax vietnamensis Ha et Grushv." Butlerov Communications 58, no. 5 (2019): 39–43. http://dx.doi.org/10.37952/roi-jbc-01/19-58-5-39.

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Since ancient times, it is known that all types of ginseng were widely used in Eastern folk medicine as a cure for many diseases. All species of the genus Panax, including Panax vietnamensis, contain saponins, but the phenolic composition has not been studied to date. Vietnamese ginseng is characterized by a unique composition of triterpene glycosides, among which the glycosylated derivatives of the rare triterpene aglycone, okothylol, are predominant. It is the only evergreen among ginsengs. As you know, a single plant can have different types of biological activity due to the content of diff

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Ying, Ang, Qing-Tao Yu, Li Guo, et al. "Structural–Activity Relationship of Ginsenosides from Steamed Ginseng in the Treatment of Erectile Dysfunction." American Journal of Chinese Medicine 46, no. 01 (2018): 137–55. http://dx.doi.org/10.1142/s0192415x18500088.

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Ginseng has been reported to have diverse pharmacological effects. One of the therapeutic claims for ginseng is to enhance sexual function. Ginsenosides are considered as the major active constituents. A steaming process can alter the ginsenoside profile of ginseng products. The structure–function relationship of ginsenosides in the treatment of erectile dysfunction (ED) has not been investigated yet. In this work, 15 different processed ginsengs are produced by steaming, and 13 major ginsensosides are quantified by liquid chromatography with UV detection, including Rg1, Re, Rf, Rb1, Rc, Rb2,

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Gu, Jinlong, Zhiyi Li, Lijuan Zhang, et al. "Research on the Quality Grading Method of Ginseng with Improved DenseNet121 Model." Electronics 13, no. 22 (2024): 4504. http://dx.doi.org/10.3390/electronics13224504.

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Ginseng is an important medicinal plant widely used in traditional Chinese medicine. Traditional methods for evaluating the visual quality of ginseng have limitations. This study presents a new method for grading ginseng’s appearance quality using an improved DenseNet121 model. We enhance the network’s capability to recognize various channel features by integrating a CA (Coordinate Attention) mechanism. We also use grouped convolution instead of standard convolution in dense layers to lower the number of model parameters and improve efficiency. Additionally, we substitute the ReLU (Rectified L

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Ayu Silfia Budiasih, Komang, and Gede Eka Handrean. "The Anti-Aging Properties Of Panax Ginseng: A Narrative Review Of Mechanisms And Clinical Evidence." International Journal of Health and Pharmaceutical (IJHP) 5, no. 1 (2025): 157–64. https://doi.org/10.51601/ijhp.v5i1.361.

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Aging is a complex physiological process influenced by various factors including oxidative stress, inflammation, and cellular damage. Natural compounds, particularly Panax ginseng, have garnered significant interest in traditional medicine for their anti-aging potential. This study aims to comprehensively review the anti-aging properties of P. ginseng, examining its traditional applications, molecular mechanisms, and clinical evidence. A narrative review methodology was employed, analyzing data from PubMed, Scopus, and Google Scholar databases, incorporating both traditional knowledge and cont

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Ge, Shengyu, Jinlong Liu, Yang Liu, et al. "Chemical Profiling, Quantitation, and Bioactivities of Ginseng Residue." Molecules 28, no. 23 (2023): 7854. http://dx.doi.org/10.3390/molecules28237854.

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Ginseng residue is a by-product stemming from the commercial extraction of ginsenosides. To assess the disparities between ginseng residue and ginseng tablet, we employed the ultra-high-performance liquid chromatography–quadrupole time-of-flight/mass spectrometry (UPLC-Q-TOF/MS) technique for sample analysis. The analyses revealed the presence of 39 compounds in both ginseng residue and ginseng tablets. Subsequently, the contents of total ginsenosides and total ginseng polysaccharides in the ginseng residue and ginseng tablet were determined. The results indicate that while only a small fracti

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Jin, Yinping, Ling Li, Reshmi Akter, et al. "Hydroponic Cultured Ginseng Leaves Zinc Oxides Nanocomposite Stabilized with CMC Polymer for Degradation of Hazardous Dyes in Wastewater Treatment." Materials 14, no. 21 (2021): 6557. http://dx.doi.org/10.3390/ma14216557.

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This study demonstrated the synthesis of o-carboxymethyl chitosan (CMC)-stabilized zinc oxide nanocomposites (ZnO NCs) combined with aqueous leaves extracts of hydroponically cultured ginseng and used as a photocatalyst for the degradation of hazardous dyes, including malachite green (MG), rhodamine B (RB), and congo red (CR) under ultraviolet illumination. Hydroponic ginseng leaves contain bioactive components, namely ginsenoside and natural polyphenol, which prompt ginseng’s biological effect. Besides, the CMC polymer is naturally biodegradable, stabilizes the nanoformation and enhances the

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Koh, Seung-Tae. "A Study on the Causes of the Decline of Ginseng Cultivation in Japan." Korea Association of World History and Culture 62 (March 31, 2022): 151–82. http://dx.doi.org/10.32961/jwhc.2022.03.62.151.

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In Japan, where ginseng did not grow naturally, ginseng seeds obtained from Joseon were sown in Nikkozan fields according to Bakufu's plan, which resulted in success of ginseng cultivation. Bakufu supplied for the domestic demand by establishing both governmental and private cultivation system for the expanded cultivation of Otane ginseng(Joseon ginseng). In addition, large quantities of white and red ginseng were exported to the Qing Dynasty, that at one time, ginseng cultivation was so prosperous that it ranked 13th among Japanese exports. However, entering the Showa era after the Meiji Rest

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Park, Eun-Young, Mi-Hwi Kim, Eung-Hwi Kim, et al. "Efficacy Comparison of Korean Ginseng and American Ginseng on Body Temperature and Metabolic Parameters." American Journal of Chinese Medicine 42, no. 01 (2014): 173–87. http://dx.doi.org/10.1142/s0192415x14500128.

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Ginseng has beneficial effects in cancer, diabetes and aging. There are two main varieties of ginseng: Panax ginseng (Korean ginseng) and Panax quinquefolius (American ginseng). There are anecdotal reports that American ginseng helps reduce body temperature, whereas Korean ginseng improves blood circulation and increases body temperature; however, their respective effects on body temperature and metabolic parameters have not been studied. We investigated body temperature and metabolic parameters in mice using a metabolic cage. After administering ginseng extracts acutely (single dose of 1000 m

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