Relevant bibliographies by topics / Glia Progenitors

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  2. Dissertations / Theses
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Academic literature on the topic 'Glia Progenitors'

Author: Grafiati
Published: 6 June 2025
Last updated: 25 July 2025

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Journal articles on the topic "Glia Progenitors"

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Pose-Méndez, Sol, Michel Rehbock, Alexandra Wolf-Asseburg, and Reinhard W. Köster. "In Vivo Monitoring of Fabp7 Expression in Transgenic Zebrafish." Cells 13, no. 13 (2024): 1138. http://dx.doi.org/10.3390/cells13131138.

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In zebrafish, like in mammals, radial glial cells (RGCs) can act as neural progenitors during development and regeneration in adults. However, the heterogeneity of glia subpopulations entails the need for different specific markers of zebrafish glia. Currently, fluorescent protein expression mediated by a regulatory element from the glial fibrillary acidic protein (gfap) gene is used as a prominent glia reporter. We now expand this tool by demonstrating that a regulatory element from the mouse Fatty acid binding protein 7 (Fabp7) gene drives reliable expression in fabp7-expressing zebrafish gl
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Morrow, Theresa, Mi-Ryoung Song, and Anirvan Ghosh. "Sequential specification of neurons and glia by developmentally regulated extracellular factors." Development 128, no. 18 (2001): 3585–94. http://dx.doi.org/10.1242/dev.128.18.3585.

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Cortical progenitor cells give rise to neurons during embryonic development and to glia after birth. While lineage studies indicate that multipotent progenitor cells are capable of generating both neurons and glia, the role of extracellular signals in regulating the sequential differentiation of these cells is poorly understood. To investigate how factors in the developing cortex might influence cell fate, we developed a cortical slice overlay assay in which cortical progenitor cells are cultured over cortical slices from different developmental stages. We find that embryonic cortical progenit
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Ojalvo-Sanz, Ana Cristina, and Laura López-Mascaraque. "Gliogenic Potential of Single Pallial Radial Glial Cells in Lower Cortical Layers." Cells 10, no. 11 (2021): 3237. http://dx.doi.org/10.3390/cells10113237.

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During embryonic development, progenitor cells are progressively restricted in their potential to generate different neural cells. A specific progenitor cell type, the radial glial cells, divides symmetrically and then asymmetrically to produce neurons, astrocytes, oligodendrocytes, and NG2-glia in the cerebral cortex. However, the potential of individual progenitors to form glial lineages remains poorly understood. To further investigate the cell progeny of single pallial GFAP-expressing progenitors, we used the in vivo genetic lineage-tracing method, the UbC-(GFAP-PB)-StarTrack. After target
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Barriola, Sonsoles, Fernando Pérez-Cerdá, Carlos Matute, Ana Bribián, and Laura López-Mascaraque. "A Clonal NG2-Glia Cell Response in a Mouse Model of Multiple Sclerosis." Cells 9, no. 5 (2020): 1279. http://dx.doi.org/10.3390/cells9051279.

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NG2-glia, also known as oligodendrocyte precursor cells (OPCs), have the potential to generate new mature oligodendrocytes and thus, to contribute to tissue repair in demyelinating diseases like multiple sclerosis (MS). Once activated in response to brain damage, NG2-glial cells proliferate, and they acquire a reactive phenotype and a heterogeneous appearance. Here, we set out to investigate the distribution and phenotypic diversity of NG2-glia relative to their ontogenic origin, and whether there is a clonal NG2-glial response to lesion in an experimental autoimmune encephalomyelitis (EAE) mu
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Dimou, Leda, and Magdalena Götz. "Glial Cells as Progenitors and Stem Cells: New Roles in the Healthy and Diseased Brain." Physiological Reviews 94, no. 3 (2014): 709–37. http://dx.doi.org/10.1152/physrev.00036.2013.

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The diverse functions of glial cells prompt the question to which extent specific subtypes may be devoted to a specific function. We discuss this by reviewing one of the most recently discovered roles of glial cells, their function as neural stem cells (NSCs) and progenitor cells. First we give an overview of glial stem and progenitor cells during development; these are the radial glial cells that act as NSCs and other glial progenitors, highlighting the distinction between the lineage of cells in vivo and their potential when exposed to a different environment, e.g., in vitro. We then proceed
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Li, Zhen, William A. Tyler, Ella Zeldich, et al. "Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex." Science Advances 6, no. 45 (2020): eabd2068. http://dx.doi.org/10.1126/sciadv.abd2068.

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How the rich variety of neurons in the nervous system arises from neural stem cells is not well understood. Using single-cell RNA-sequencing and in vivo confirmation, we uncover previously unrecognized neural stem and progenitor cell diversity within the fetal mouse and human neocortex, including multiple types of radial glia and intermediate progenitors. We also observed that transcriptional priming underlies the diversification of a subset of ventricular radial glial cells in both species; genetic fate mapping confirms that the primed radial glial cells generate specific types of basal proge
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Gray, G. E., and J. R. Sanes. "Lineage of radial glia in the chicken optic tectum." Development 114, no. 1 (1992): 271–83. http://dx.doi.org/10.1242/dev.114.1.271.

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In many parts of the central nervous system, the elongated processes of radial glial cells are believed to guide immature neurons from the ventricular zone to their sites of differentiation. To study the clonal relationships of radial glia to other neural cell types, we used a recombinant retrovirus to label precursor cells in the chick optic tectum with a heritable marker, the E. coli lacZ gene. The progeny of the infected cells were detected at later stages of development with a histochemical stain for the lacZ gene product. Radial glia were identified in a substantial fraction of clones, an
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Hui, Subhra Prakash, Tapas Chandra Nag, and Sukla Ghosh. "Neural cells and their progenitors in regenerating zebrafish spinal cord." International Journal of Developmental Biology 64, no. 4-5-6 (2020): 353–66. http://dx.doi.org/10.1387/ijdb.190130sg.

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The zebrafish (Danio rerio), among all amniotes is emerging as a powerful model to study vertebrate organogenesis and regeneration. In contrast to mammals, the adult zebrafish is capable of regenerating damaged axonal tracts; it can replace neurons and glia lost after spinal cord injury (SCI) and functionally recover. In the present paper, we report ultrastructural and cell biological analyses of regeneration processes after SCI. We have focused on event specific analyses of spinal cord regeneration involving different neuronal and glial cell progenitors, such as radial glia, oligodendrocyte p
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Pawolski, Verena, and Mirko H. H. Schmidt. "Neuron–Glia Interaction in the Developing and Adult Enteric Nervous System." Cells 10, no. 1 (2020): 47. http://dx.doi.org/10.3390/cells10010047.

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The enteric nervous system (ENS) constitutes the largest part of the peripheral nervous system. In recent years, ENS development and its neurogenetic capacity in homeostasis and allostasishave gained increasing attention. Developmentally, the neural precursors of the ENS are mainly derived from vagal and sacral neural crest cell portions. Furthermore, Schwann cell precursors, as well as endodermal pancreatic progenitors, participate in ENS formation. Neural precursors enherite three subpopulations: a bipotent neuron-glia, a neuronal-fated and a glial-fated subpopulation. Typically, enteric neu
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Nagashima, Mikiko, and Peter F. Hitchcock. "Inflammation Regulates the Multi-Step Process of Retinal Regeneration in Zebrafish." Cells 10, no. 4 (2021): 783. http://dx.doi.org/10.3390/cells10040783.

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The ability to regenerate tissues varies between species and between tissues within a species. Mammals have a limited ability to regenerate tissues, whereas zebrafish possess the ability to regenerate almost all tissues and organs, including fin, heart, kidney, brain, and retina. In the zebrafish brain, injury and cell death activate complex signaling networks that stimulate radial glia to reprogram into neural stem-like cells that repair the injury. In the retina, a popular model for investigating neuronal regeneration, Müller glia, radial glia unique to the retina, reprogram into stem-like c
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Dissertations / Theses on the topic "Glia Progenitors"

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Murdoch, Barbara. "Identification, regulation and lineage tracing of embryonic olfactory progenitors." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/994.

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Neurogenesis occurs in exclusive regions in the adult nervous system, the subventricular zone and dentate gyrus in the brain, and olfactory epithelium (OE) in the periphery. Cell replacement after death or injury, occurs to varying degrees in neural tissue, and is thought to be dependent upon the biological responses of stem and/or progenitor cells. Despite the progress made to identify adult OE and central nervous system (CNS) progenitors and lineage trace their progeny, our spatial and temporal understanding of embryonic OE neuroglial progenitors has been stalled by the paucity of identifiab
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Belmonte, Mateos Carla 1992. "Unveiling the molecular and behavioral properties of hindbrain rhombomere centers." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2022. http://hdl.handle.net/10803/673433.

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Precise regulation of neurogenesis is achieved by differentially allocating the neurogenic competence along the tissue. In the hindbrain proneural gene expression is stereotypically confined in segment boundary-adjacent regions, hence, being absent in segment centers. This segregation of proneural gene expression therefore hints rhombomere centers as a putative non-neurogenic population. In this work, we unveil their spatiotemporal molecular profile as well as one of the mechanisms involved in their maintenance as non-committed progenitors. By 4D imaging we shed light for the first time in
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BOZZO, MATTEO. "Glial cells of the developing amphioxus: a molecular study." Doctoral thesis, Università degli studi di Genova, 2021. http://hdl.handle.net/11567/1043680.

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Glial cells play important roles in the development and homeostasis of metazoan nervous systems. However, while their involvement in the development and function in the central nervous system (CNS) of vertebrates is increasingly well understood, much less is known about invertebrate glia and the evolutionary history of glial cells more generally. An investigation into amphioxus glia is therefore timely, as this organism is the best living proxy for the last common ancestor of all chordates, and hence provides a window on the role of glial cells development and function at the transition b
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Badsha, Farhath. "A comparative study of neocortical development between humans and great apes." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-224196.

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The neocortex is the most recently evolved part of the mammalian brain which is involved in a repertoire of higher order brain functions, including those that separate humans from other animals. Humans have evolved an expanded neocortex over the course of evolution through a massive increase in neuron number (compared to our close relatives-­‐‑ the chimpanzees) in spite of sharing similar gestation time frames. So what do humans do differently compared to chimpanzees within the same time frame during their development? This dissertation addresses this question by comparing the developmental pr
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Najas, Sales Sònia 1985. "Role of DYRK1A in the development of the cerebral cortex : Implication in Down Syndrome." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/380895.

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In this work we have assessed the possible contribution of the human chromosome-21 gene DYRK1A in the developmental cortical alterations associated with Down Syndrome using the mBACTgDyrk1a mouse, which carries 3 copies of Dyrk1a, and a trisomic model of the syndrome, the Ts65Dn mouse. We show that trisomy of Dyrk1a changes the cell cycle parameters of dorsal telencephalic radial glial (RG) progenitors and the division mode of these progenitors leading to a deficit in glutamatergic neurons that persist until the adulthood. We demonstrate that Dyrk1a is the triplicated gene that causes the defi
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Than, Trong Emmanuel. "Le rôle de la signalisation Notch3 dans le maintien des cellules souches neurales du télencéphale adulte Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signaling cascade in the vertebrate adult brain her4-expressing neural stem cells are maintained through population asymmetry and embedded into a hierarchy of progenitors responsible for their life-long expansion Radial Glia and Neural Progenitors in the Adult Zebrafish Central Nervous System." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS541.

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Un certain nombre de régions du cerveau des vertébrés, y compris chez l’homme, continuent d’être le siège de l’ajout de nouveaux neurones à l’âge adulte. Ces nouveaux neurones sont produits à partir de cellules spécialisées, appelées cellules souches neurales (CSN). Celles-ci sont capables de s’auto-renouveler et sont principalement trouvées dans un état d’arrêt transitoire du cycle cellulaire que l’on appelle quiescence. A l’heure actuelle, les mécanismes cellulaires et moléculaires permettant aux CSN de trouver un équilibre entre maintien et différentiation, ainsi que les règles générales go
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Smith, Maria Civita. "MAPPING ASTROCYTE DEVELOPMENT IN THE DORSAL CORTEX OF THE MOUSE BRAIN." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1373039738.

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Chapman, Heather M. "Gsx genes control the neuronal to glial fate switch in telencephalic progenitors." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1394725163.

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Beligala, Dilshan Harshajith. "Stem-like cells and glial progenitors in the adult mouse suprachiasmatic nucleus." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566319291491512.

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Bizzotto, Sara. "Eml1 in radial glial progenitors during cortical development : the neurodevelopmental role of a protein mutated in subcortical heterotopia in mouse and human." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066118.

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Le développement du cortex cérébral résulte de processus de prolifération, neurogenèse, migration et différenciation cellulaire qui sont contrôlés génétiquement. Les malformations corticales qui résultent d'anomalies de ces processus sont associées à l'épilepsie et la déficience intellectuelle. Nous avons étudié la souris mutante HeCo (heterotopic cortex), qui présente une hétérotopie sous-cortical bilatérale (neurones présents dans la substance blanche) et nous avons identifié la présence d'une mutation sur le gène Eml1 (Echinoderm Microtubule-associated protein-Like 1). De plus, des mutation
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Books on the topic "Glia Progenitors"

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Leone, Dino. Tamoxifen-inducible glia-specific cre mice for somatic mutagenesis in oligodendrocytes and schwann cells and [beta]1-integrin regulates neural progenitor maintenance through modulation of growth factor signaling. 2003.

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Book chapters on the topic "Glia Progenitors"

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Eugenín-von Bernhardi, Jaime, and Leda Dimou. "NG2-glia, More Than Progenitor Cells." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40764-7_2.

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Bosch, E. Peter, José G. Assouline, and Ramon Lim. "In Vitro Effects of Glia Maturation Factor on Bipotential Glial Progenitor Cells." In Model Systems of Development and Aging of the Nervous System. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-2037-1_10.

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Scolding, Neil. "The adult human oligodendrocyte progenitor." In Molecular Signaling and Regulation in Glial Cells. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60669-4_25.

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Franklin, Robin J. M. "The biology of the transplanted oligodendrocyte progenitor." In Molecular Signaling and Regulation in Glial Cells. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60669-4_32.

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Balasubramanian, Swarnalatha, Elizabeth M. Powell, and Jennie B. Leach. "Culturing Neurons, Glia, and Progenitor Cells in Three-Dimensional Hydrogels." In Extracellular Matrix. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2083-9_9.

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Ader, Marius, Volker Enzmann, and Mike Francke. "Potential of Müller Glia and Stem/Progenitor Cells to Regenerate Retinal Tissue." In Stem Cell Biology and Regenerative Medicine. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0787-8_8.

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Espinosa, A., D. Espejo, and J. de Vellis. "Transplantation of Oligodendrocyte Progenitors and CG4 Cells into the Dveloping Rat Brain: Differences and Similarities." In Molecular Signaling and Regulation in Glial Cells. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60669-4_29.

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Nishikawa, Masashi, Koh-ichi Nagata, and Hidenori Tabata. "Live Imaging of Migrating Neurons and Glial Progenitors Visualized by in Utero Electroporation." In Methods in Molecular Biology. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3810-1_17.

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Nelson, Craig M., and David R. Hyde. "Müller Glia as a Source of Neuronal Progenitor Cells to Regenerate the Damaged Zebrafish Retina." In Retinal Degenerative Diseases. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-0631-0_54.

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Small, R. "Differentiation of a Migratory Bipotential Glial Progenitor Cell in the Developing Rat Optic Nerve." In Neural Development and Regeneration. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73148-8_71.

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Conference papers on the topic "Glia Progenitors"

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Sudina, A. K., D. V. Goldshtein, D. N. Silachev, and D. I. Salikhova. "GLIAL PROGENITOR CELL TRANSPLANTATION ENHANCES RECOVERY OF SENSORIMOTOR DEFICITS IN RATS AFTER TRAUMATIC BRAIN INJURY." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-105.

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The search for new methods of therapy of traumatic brain injury is one of the important tasks of modern biomedicine. In this work, the therapeutic effect of glial progenitor cells obtained from induced pluripotent stem cells was investigated in an experimental model of traumatic brain injury.
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Grinchevskaia, L. R., D. I. Salikhova, T. K. Fatkhudinov, and D. V. Goldshtein. "THE ROLE OF GLIAL PROGENITOR CELLS IN ANGIOGENESIS." In NOVEL TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. LLC Institute Information Technologies, 2024. http://dx.doi.org/10.47501/978-5-6044060-4-5.205-209.

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Diseases associated with impaired blood supply to organs and tissues are one of the common causes of mortality in the world. Despite their high frequency of occurrence, the effectiveness of existing therapies remains insufficient, so it is important to search for new ways of therapy of ischemic tissues.
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