Log in

Relevant bibliographies by topics / Glia Progenitors / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Glia Progenitors.

Dissertations / Theses on the topic 'Glia Progenitors'

Author: Grafiati

Published: 6 June 2025

Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 27 dissertations / theses for your research on the topic 'Glia Progenitors.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Murdoch, Barbara. "Identification, regulation and lineage tracing of embryonic olfactory progenitors." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/994.

Full text

Abstract:

Neurogenesis occurs in exclusive regions in the adult nervous system, the subventricular zone and dentate gyrus in the brain, and olfactory epithelium (OE) in the periphery. Cell replacement after death or injury, occurs to varying degrees in neural tissue, and is thought to be dependent upon the biological responses of stem and/or progenitor cells. Despite the progress made to identify adult OE and central nervous system (CNS) progenitors and lineage trace their progeny, our spatial and temporal understanding of embryonic OE neuroglial progenitors has been stalled by the paucity of identifiab

APA, Harvard, Vancouver, ISO, and other styles

2

Belmonte, Mateos Carla 1992. "Unveiling the molecular and behavioral properties of hindbrain rhombomere centers." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2022. http://hdl.handle.net/10803/673433.

Full text

Abstract:

Precise regulation of neurogenesis is achieved by differentially allocating the neurogenic competence along the tissue. In the hindbrain proneural gene expression is stereotypically confined in segment boundary-adjacent regions, hence, being absent in segment centers. This segregation of proneural gene expression therefore hints rhombomere centers as a putative non-neurogenic population. In this work, we unveil their spatiotemporal molecular profile as well as one of the mechanisms involved in their maintenance as non-committed progenitors. By 4D imaging we shed light for the first time in

APA, Harvard, Vancouver, ISO, and other styles

3

BOZZO, MATTEO. "Glial cells of the developing amphioxus: a molecular study." Doctoral thesis, Università degli studi di Genova, 2021. http://hdl.handle.net/11567/1043680.

Full text

Abstract:

Glial cells play important roles in the development and homeostasis of metazoan nervous systems. However, while their involvement in the development and function in the central nervous system (CNS) of vertebrates is increasingly well understood, much less is known about invertebrate glia and the evolutionary history of glial cells more generally. An investigation into amphioxus glia is therefore timely, as this organism is the best living proxy for the last common ancestor of all chordates, and hence provides a window on the role of glial cells development and function at the transition b

APA, Harvard, Vancouver, ISO, and other styles

4

Badsha, Farhath. "A comparative study of neocortical development between humans and great apes." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-224196.

Full text

Abstract:

The neocortex is the most recently evolved part of the mammalian brain which is involved in a repertoire of higher order brain functions, including those that separate humans from other animals. Humans have evolved an expanded neocortex over the course of evolution through a massive increase in neuron number (compared to our close relatives-‐‑ the chimpanzees) in spite of sharing similar gestation time frames. So what do humans do differently compared to chimpanzees within the same time frame during their development? This dissertation addresses this question by comparing the developmental pr

APA, Harvard, Vancouver, ISO, and other styles

5

Najas, Sales Sònia 1985. "Role of DYRK1A in the development of the cerebral cortex : Implication in Down Syndrome." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/380895.

Full text

Abstract:

In this work we have assessed the possible contribution of the human chromosome-21 gene DYRK1A in the developmental cortical alterations associated with Down Syndrome using the mBACTgDyrk1a mouse, which carries 3 copies of Dyrk1a, and a trisomic model of the syndrome, the Ts65Dn mouse. We show that trisomy of Dyrk1a changes the cell cycle parameters of dorsal telencephalic radial glial (RG) progenitors and the division mode of these progenitors leading to a deficit in glutamatergic neurons that persist until the adulthood. We demonstrate that Dyrk1a is the triplicated gene that causes the defi

APA, Harvard, Vancouver, ISO, and other styles

6

Than, Trong Emmanuel. "Le rôle de la signalisation Notch3 dans le maintien des cellules souches neurales du télencéphale adulte Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signaling cascade in the vertebrate adult brain her4-expressing neural stem cells are maintained through population asymmetry and embedded into a hierarchy of progenitors responsible for their life-long expansion Radial Glia and Neural Progenitors in the Adult Zebrafish Central Nervous System." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS541.

Full text

Abstract:

Un certain nombre de régions du cerveau des vertébrés, y compris chez l’homme, continuent d’être le siège de l’ajout de nouveaux neurones à l’âge adulte. Ces nouveaux neurones sont produits à partir de cellules spécialisées, appelées cellules souches neurales (CSN). Celles-ci sont capables de s’auto-renouveler et sont principalement trouvées dans un état d’arrêt transitoire du cycle cellulaire que l’on appelle quiescence. A l’heure actuelle, les mécanismes cellulaires et moléculaires permettant aux CSN de trouver un équilibre entre maintien et différentiation, ainsi que les règles générales go

APA, Harvard, Vancouver, ISO, and other styles

7

Smith, Maria Civita. "MAPPING ASTROCYTE DEVELOPMENT IN THE DORSAL CORTEX OF THE MOUSE BRAIN." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1373039738.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Chapman, Heather M. "Gsx genes control the neuronal to glial fate switch in telencephalic progenitors." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1394725163.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Beligala, Dilshan Harshajith. "Stem-like cells and glial progenitors in the adult mouse suprachiasmatic nucleus." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566319291491512.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Bizzotto, Sara. "Eml1 in radial glial progenitors during cortical development : the neurodevelopmental role of a protein mutated in subcortical heterotopia in mouse and human." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066118.

Full text

Abstract:

Le développement du cortex cérébral résulte de processus de prolifération, neurogenèse, migration et différenciation cellulaire qui sont contrôlés génétiquement. Les malformations corticales qui résultent d'anomalies de ces processus sont associées à l'épilepsie et la déficience intellectuelle. Nous avons étudié la souris mutante HeCo (heterotopic cortex), qui présente une hétérotopie sous-cortical bilatérale (neurones présents dans la substance blanche) et nous avons identifié la présence d'une mutation sur le gène Eml1 (Echinoderm Microtubule-associated protein-Like 1). De plus, des mutation

APA, Harvard, Vancouver, ISO, and other styles

11

Bizzotto, Sara. "Eml1 in radial glial progenitors during cortical development : the neurodevelopmental role of a protein mutated in subcortical heterotopia in mouse and human." Electronic Thesis or Diss., Paris 6, 2016. http://www.theses.fr/2016PA066118.

Full text

Abstract:

Le développement du cortex cérébral résulte de processus de prolifération, neurogenèse, migration et différenciation cellulaire qui sont contrôlés génétiquement. Les malformations corticales qui résultent d'anomalies de ces processus sont associées à l'épilepsie et la déficience intellectuelle. Nous avons étudié la souris mutante HeCo (heterotopic cortex), qui présente une hétérotopie sous-cortical bilatérale (neurones présents dans la substance blanche) et nous avons identifié la présence d'une mutation sur le gène Eml1 (Echinoderm Microtubule-associated protein-Like 1). De plus, des mutation

APA, Harvard, Vancouver, ISO, and other styles

12

Fair, Joel Vincent. "Gli2 Accelerates Cardiac Progenitor Gene Expression During Mouse Embryonic Stem Cell Differentiation." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31579.

Full text

Abstract:

The Hedgehog (HH) signalling pathway and its primary transducer, GLI2, regulate cardiomyogenesis in vivo and in differentiating P19 embryonal carcinoma (EC) cells. To further assess the role of HH signalling during mouse embryonic stem (mES) cell differentiation, we studied the effects of GLI2 overexpression during mES cell differentiation. GLI2 overexpression resulted in temporal enhancement of cardiac progenitor genes, Mef2c and Nkx2-5, along with enhancement of Tbx5, Myhc6, and Myhc7 in day 6 differentiating mES cells. Mass spectrometric analysis of proteins that immunoprecipitate with GLI2

APA, Harvard, Vancouver, ISO, and other styles

13

Uzquiano, López Ana. "Progenitor cell mechanisms contributing to cortical malformations : studying the role of the heterotopia gene Eml1/EML1 in radial glia." Electronic Thesis or Diss., Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2019SORUS392.pdf.

Full text

Abstract:

Le cortex cérébral se développe à partir des zones de prolifération des cellules progénitrices dont le comportement anormal peut donner lieu à des malformations corticales. Des mutations dans Eml1/EML1 ont été identifiées chez la souris HeCo, ainsi que dans trois familles présentant une hétérotopie sous-corticale (SH). La SH se caractérise par une position aberrante des neurones dans la substance blanche. Chez la souris HeCo, des anomalies de position des progéniteurs de la glie radiale apicale (aRG) ont été observées aux stades précoces de la corticogenèse. Je me suis concentré sur la caracté

APA, Harvard, Vancouver, ISO, and other styles

14

Kadoshima, Taisuke. "Self-organization of axial polarity, inside-out layer pattern and species-specific progenitor dynamics in human ES cell-derived neocortex." Kyoto University, 2014. http://hdl.handle.net/2433/188695.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Iacobucci, Simona. "Function of the histone demethylase PHF8 in neural progenitor cells and glial differentiation." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/673438.

Full text

Abstract:

Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural stem cells biology. To do that, we determined the following objectives: 1. To investigate the role of PHF8 histone demethylase during astrocytes differentiation. • Analyse the PHF8-mediated transcriptional profile in astrocytes. • Determine the chromatin bound regions of PHF8 in astrocytes. • Elucidate astrocytes phenotype upon PHF8 depletion. • Examine astrocytic PHF8 function during syna

APA, Harvard, Vancouver, ISO, and other styles

16

Gallina, Donika. "The Role of Glucocorticoid Receptor-signaling and Wnt-signaling in Avian Retinal Regeneration." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1439204931.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

McLean, Will (Will James). "Defined populations of inner ear progenitor cells show limited and distinct capacities for differentiation into hair cells, neurons, and glia." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/97320.

Full text

Abstract:

Thesis: Ph. D., Harvard-MIT Program in Health Sciences and Technology, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 66-74).<br>Despite the fact that mammalian hair cells and neurons do not naturally regenerate in vivo, progenitor cells exist within the postnatal inner ear that can be manipulated to generate hair cells and neurons. This work reveals the differentiation capabilities of distinct inner ear progenitor populations and pinpoints cell types that can become cochlear hair cells, vestibular hair cells, neurons, and CNS glia. We expanded and

APA, Harvard, Vancouver, ISO, and other styles

18

Chen, Yan. "EFFECTS OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) ON STEM/PROGENITOR CELL PROLIFERATION AND DIFFERENTIATION." UKnowledge, 2005. http://uknowledge.uky.edu/gradschool_diss/233.

Full text

Abstract:

Stem/progenitor cells are present in the adult brain; they undergo constantproliferation and differentiate into mature neurons in certain brain areas, a phenomenoncalled neurogenesis. This study investigated the effects of GDNF, a potent trophic factorof dopaminergic neurons, on neurogenesis in the brain. Nestin and 5-Bromo-2'-deoxyuridine (BrdU) were used as stem/progenitor cells markers.First, we observed extensive bilateral increases of stem/progenitor cells in thedentate gyrus and substantia nigra after continuous infusion of GDNF into the normal ratbrain. However, none of the BrdU+ cells

APA, Harvard, Vancouver, ISO, and other styles

19

Ringuette, Randy. "The Role of Signaling Pathway Integration in Neurogenesis." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35108.

Full text

Abstract:

Proper central nervous system development is critical for survival and depends on complex intracellular and extracellular signaling to regulate neural progenitor cell growth and differentiation; however, the mechanisms that mediate molecular crosstalk between pathways during neurogenesis are not fully understood. Here, we explored the integration of the Hedgehog (Hh) signaling pathway with the two critical developmental pathways, Receptor Tyrosine Kinase (RTK) and Notch signaling, in the growth and maintenance of neural progenitors in the developing neuroretina. We found combined and sustain

APA, Harvard, Vancouver, ISO, and other styles

20

Hahn, Yun Kyung. "CNS Neural/Glial Progenitors as Targets of HIV-1 and Opiates: Effects on Proliferation and Population Dynamics May Alter Behavior Outcomes." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/311.

Full text

Abstract:

Human immunodeficiency virus (HIV) infected patients with a history of injection opiate abuse have higher incidences of acquired immunodeficiency syndrome (AIDS) and neurological dysfunction. The use of combined anti-retroviral therapy has significantly reduced the prevalence of mortality and progression to AIDS. Due to extended life expectancy, these patients are still at a great risk for HIV-associated neurological disorders and impairment in their later life. Neural progenitor cells (NPCs) play critical roles in brain growth and repair after injury and insult. Pediatric HIV patients whose g

APA, Harvard, Vancouver, ISO, and other styles

21

Marín, Alexandra Belén Saona. "Capacidade proliferativa in vitro de precursores neuro-gliais, telencefálicos e expressão dos genes 1 e 2 do Complexo da Esclerose Tuberosa (TSC1 e TSC2)." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-08032013-105224/.

Full text

Abstract:

O complexo da esclerose tuberosa (TSC) é um transtorno clínico, com expressividade variável, caracterizado por hamartomas que podem ocorrer em diferentes órgãos. Tem herança autossômica dominante e é devido a mutações em um de dois genes supressores de tumor, TSC1 ou TSC2. Estes codificam para as proteínas hamartina e tuberina, respectivamente, que se associam formando um complexo macromolecular que regula funções como proliferação, diferenciação, crescimento e migração celular. As lesões cerebrais podem ser muito graves em pacientes com TSC e caracterizam-se por nódulos subependimários (SEN),

APA, Harvard, Vancouver, ISO, and other styles

22

Lindberg, Nanna. "Cellular Origin and Development of Glioma." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109486.

Full text

Abstract:

Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. I have developed a life-like orthotopic glioma model and used this and other in vivo models to study basic mechanisms of glioma development and treatment. Previous studies had indicated that experimental gliomas could arise from glial stem cells and astrocytes. The present thesis describes the making and characterization of a novel mouse model, Ctv-a, where gliomas are i

APA, Harvard, Vancouver, ISO, and other styles

23

Nicola, Fabrício do Couto. "Efeito neuroprotetor do transplante de células-tronco mesenquimais derivadas de dente decíduo humano em ratos Wistar submetidos à lesão medular." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/170284.

Full text

Abstract:

A lesão medular (LM) é uma patologia incapacitante que resulta em déficits sensoriais e motores. No Brasil, a incidência anual é de 30 novos casos de lesão medular a cada 1 milhão de indivíduos e, infelizmente, a LM permanece sem um tratamento eficaz. Células-tronco derivadas do dente decíduo humano estão entre as potenciais fontes de células-tronco para transplante após a lesão medular, cujo objetivo é de promover a proteção ou a recuperação da lesão na medula espinal. Buscou-se nesta tese avaliar os efeitos do transplante, uma hora após a lesão, das células tronco de dente decíduo humano (SH

APA, Harvard, Vancouver, ISO, and other styles

24

Leoni, G., Marcus Rattray, D. Fulton, A. Rivera, and A. M. Butt. "Immunoablation of cells expressing the NG2 chondroitin sulphate proteoglycan." 2014. http://hdl.handle.net/10454/7810.

Full text

Abstract:

Yes<br>Expression of the transmembrane NG2 chondroitin sulphate proteoglycan (CSPG) defines a distinct population of NG2-glia. NG2-glia serve as a regenerative pool of oligodendrocyte progenitor cells in the adult central nervous system (CNS), which is important for demyelinating diseases such as multiple sclerosis, and are a major component of the glial scar that inhibits axon regeneration after CNS injury. In addition, NG2-glia form unique neuron–glial synapses with unresolved functions. However, to date it has proven difficult to study the importance of NG2-glia in any of these functio

APA, Harvard, Vancouver, ISO, and other styles

25

Hsin-YuSung and 宋欣諭. "Regulation of Interleukin-33 in glial progenitor cell proliferation and oligodendrocyte differentiation." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/4u4vq2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Ozacar, Ayse Tuba. "Regulation of the hypothalamic progenitor cells by Hh/Gli signaling in post-embryonic zebrafish." 2012. https://scholarworks.umass.edu/dissertations/AAI3545969.

Full text

Abstract:

The major goals of my research were to characterize the hypothalamic neural progenitors and to understand how Hh/Gli signaling plays a role in regulating cell proliferation in the hypothalamic neurogenic zone. In contrast to mammals, the zebrafish brain has a life-long potential to grow continuously. Thus, for comparative neurogenesis studies, zebrafish become an indispensible model organism to understand adult neurogenesis and regulatory signaling pathways. Identification of the regulatory mechanisms underlying the controlled cell proliferation in adult zebrafish brain will pave the way to ma

APA, Harvard, Vancouver, ISO, and other styles

27

Harun-Or-Rashid, Mohammad. "Modulation of the Progenitor Cell and Homeostatic Capacities of Müller Glia Cells in Retina : Focus on α2-Adrenergic and Endothelin Receptor Signaling Systems". Doctoral thesis, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-281569.

Full text

Abstract:

Müller cells are major glial cells in the retina and have a broad range of functions that are vital for the retinal neurons. During retinal injury gliotic response either leads to Müller cell dedifferentiation and formation of a retinal progenitor or to maintenance of mature Müller cell functions. The overall aim of this thesis was to investigate the intra- and extracellular signaling of Müller cells, to understand how Müller cells communicate during an injury and how their properties can be regulated after injury. Focus has been on the α2-adrenergic receptor (α2-ADR) and endothelin receptor (

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!