Dissertations / Theses on the topic 'Global Supply Chain Management'
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MENDOZA, ANDRE LUIZ. "GLOBAL SUPPLY CHAIN MANAGEMENT AT GLAXOSMITHKLINE." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2006. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=9957@1.
Full textPharmaceutical companies need to address the growing demand for bringing medicines to market in an economical way. Price pressure is increasing, and the advantages of having a buffered patent window is decreasing as generic manufacturing is on the rise. Having a pipeline of new drugs is critical, but it is also critical the ability to bring them to market in a cost effective and efficient manner. However, pharmaceutical companies can no longer solely rely on research and development and marketing to survive, but must also rely on supply chain management to deliver value. Within this context, this dissertation intends to analyze the supply chain management model of a major pharmaceutical company (GlaxoSmithkline - GSK) throughout an overview of the key characteristics of its supply chain, supply and demand management and some examples of projects implemented in Europe.
Horch, Nils. "Management control of global supply chains." Lohmar Köln Eul, 2009. http://d-nb.info/999285874/04.
Full textRao, Venkatesh G. (Venkatesh Gopalkrishna) 1971. "Strategic cost management in a global supply chain." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/34775.
Full textIncludes bibliographical references (p. 100).
In the face of an economic downturn, cost has become a focal point of supply chain management. Cost management is increasingly being recognized as a vital core competency needed for survival. As companies transition from being vertically integrated to pursuing increasingly outsourced manufacturing strategies, modeling and monitoring the total cost of manufacturing products has become crucial, and complicated. In the context of the automated test equipment industry, this thesis explores the impact of outsourcing on product cost and cost management practices. It examines prevailing cost management practices with reference to design and procurement, as well as methods to leverage information technology and re-engineer business processes to manage "spend" effectively and efficiently. It surveys capabilities that are available through software and examines cost-benefit tradeoffs that have to be addressed in selecting such systems.
by Venkatesh G. Rao.
S.M.
M.B.A.
Sadeghi, Azadeh. "Global Supply Chain Inventory Management and Production Planning Strategies." Ohio University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1509528764663001.
Full textHenkle, Aimee L. (Aimee Leigh) 1975. "Global supply chain design and optimization methodology." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/34762.
Full textIncludes bibliographical references (p. 72).
The work for this thesis was performed at Honeywell in the Automation and Control Solutions (ACS) division. The project focuses on ACS's manufacturing strategy regarding its global supply chain design, primarily discussing the manufacturing growth opportunities available in emerging regions. Honeywell ACS's current methodology for the development of a long-term manufacturing strategy is based on growth and total cost reduction objectives. In order to comprehend the total cost of the manufacturing strategy, considerations such as inventory, logistics and duties, outsourcing and material sourcing are evaluated. The project also considers a factory's geographical location and ACS's year-by-year implementation plan. An outcome of this Honeywell project and the basis of this thesis is the development of a general supply chain design and optimization methodology that utilizes three analytical tools (Country Selection Framework, Total Cost Model and Implementation Plan Process) that are capable of validating the supply chain design of any company. The analytical tools can be used to verify key strategic supply chain decisions or to create a baseline manufacturing strategy. The following results can be determined using this supply chain design methodology: Determine an appropriate operating region for current or future business needs; Evaluate the feasibility of factory relocation projects by considering all relevant costs; Evaluate the cost implications of the supply chain structure by considering logistics, inventory and material sourcing costs; Understand the impact of outsourcing on the manufacturing strategy; Recommend a year-by-year implementation plan in the case of multiple projects and limited capital resources.
by Aimee L. Henkle.
S.M.
M.B.A.
Ye, Zi. "Supply chain risk management on natural disaster : A study of global supply chain influence by2011Tohoku earthquake." Thesis, Högskolan i Gävle, Akademin för teknik och miljö, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-11327.
Full textNigh, Silvia. "The Managerial Impact on Small Business Global Supply Chain." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3360.
Full textShaalan, Tarek. "OPTIMIZING THE GLOBAL PERFORMANCE OF BUILD-TO-ORDER SUPPLY CHAINS." Doctoral diss., University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4133.
Full textPh.D.
Department of Industrial Engineering and Management Systems
Engineering and Computer Science
Industrial Engineering and Management Systems
Wang, Letian. "Global supply chain risk management through operational and financial hedges." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95041.
Full textLa thèse consiste en deux papiers qui étudient l'impact de la couverture opérationnelle et/ou financière sur la gestion du risque dans la chaine de distribution globale. Les problèmes proviennent du fait que beaucoup de firmes nord-américaine sous-contracte une bonne partie de leurs opérations à des fournisseurs situé outre-mer, notamment en Chine, en Inde, au Vietnam ainsi que dans d'autres pays. Les résultats théoriques et numériques obtenu dans cette thèse donnent un aperçu des méthodes de gestion pour mitiger le risque de demande et le risque de taux de change, lors de la sous-traitance à des firmes situés à l'étranger. Le premier papier étudie les stratégies de couverture opérationnelles pour les firmes qui font face à la fois à des incertitudes sur le taux de change et sur la demande. La couverture opérationnelle se présente sous la forme d'une option réelle de changer la production entre des fournisseurs locaux et outre-mer. Nous démontrons que les firmes bénéficient à conserver des capacités de production avec les deux types de fournisseurs. La valeur de l'option opérationnelle augmente avec l'incertitude sur les taux de change et sur la demande. De plus lorsque les firmes sont averse au risque, elles peuvent utilisées les capacités locales pour se couvrir contre les capacités outre-mer. Il en résulte que les firmes peuvent choisir de maintenir la capacité locale même si elle montre une contribution marginale négative au profit. De plus des firmes averses au risque peuvent maintenir encore davantage de capacité. Le deuxième papier étend le premier papier and incluant les stratégies de couverture financière. Dans ce papier nous étudions les problèmes de planification de la capacité de production, dans lesquels les firmes planifient de réserver des capacités de production avec des fournisseurs potentiels situés dans plusieurs pays afin de se couvrir contre le risque de demande et de taux de change. Nous off
Ben-Simon, Yaakov (Yaakov Kobi). "Where India fits within Flextronics global supply chain." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39592.
Full textIncludes bibliographical references (p. 66-67).
This project focuses on Flextronics International manufacturing strategy regarding its global supply chain design, and its export strategy from India. It also focuses on the application of the Flextronics case to the question of India's role in global electronics manufacturing. Following China's successful economic model, India is establishing itself as a global manufacturing hub by attracting multinational companies. Over time, India has the potential to become a large end-market for electronic products. In addition, India's low-cost labor-base may allow it to become a lucrative manufacturing location for export markets. On the other hand, the infrastructure is problematic, the component supply base is extremely undeveloped, and extensive competition exists from well-developed, low-cost Asian countries. This thesis examines the competitive advantage and disadvantage of export-oriented electronic manufacturing in India. It studies the business environment in India in terms of infrastructure, taxes, bureaucracy, and government policies. The thesis also identifies high potential products for manufacturing in India, and compares the total cost in India to the cost in China for the manufacture of a mechanical enclosure.
(cont.) For the mechanical enclosure, this analysis establishes that India can be as competitive as China on a cost basis. The study also looks beyond cost to identify the key challenges for high-volume manufacturing in India and suggest ways to address them.
by Yaakov (Kobi) Ben-Simon.
S.M.
M.B.A.
Lee, Esther S. M. Massachusetts Institute of Technology. "Global demand transparency in the ABB supply chain." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/75661.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 80).
This paper attempts to provide a solution to a problem facing many multinational firms: the lack of an accessible and comprehensive database for up-to-date component part forecasts. We consider this problem in the context of ABB BU DMPE. After considering various requirements and constraints regarding the consolidation of forecasting information, we propose a novel combination of standardized process and the use of certain IT tools as a first step. After a test run, we discovered that consolidation of forecasting information increases transparency within the supply chain. As a corollary result of our pilot program, we propose that prior to any attempt at consolidation, enforcement of a standardized form and method of forecasting at the local level.
by Esther Lee.
M.B.A.
S.M.
Ozkaya, Evren. "Demand management in global supply chains." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26617.
Full textCommittee Chair: Keskinocak, Pinar; Committee Co-Chair: Vande Vate, John; Committee Member: Ferguson, Mark; Committee Member: Griffin, Paul; Committee Member: Swann, Julie. Part of the SMARTech Electronic Thesis and Dissertation Collection.
Asree, Susita. "Challenges in the Global Supply Chain: Exploitation versus Exploration Strategy." Toledo, Ohio : University of Toledo, 2010. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1271874448.
Full textTypescript. "Submitted to the Graduate Faculty as partial fulfillment of the requirements for The Doctor of Philosophy in Manufacturing Management and Engineering." "A dissertation entitled"--at head of title. Title from title page of PDF document. Bibliography: p. 158-180.
Erasmus, Jens Henning. "Qualitätsmanagement in global verteilten Wertschöpfungsprozessen : ein fertigungsorganisatorischer Lösungsansatz zur wirtschaftlichen Erzeugung einer qualitätsfähigen Zulieferkette /." Aachen : Shaker, 2008. http://d-nb.info/991378962/04.
Full textKorrmann, Franziska. "International Production and Global Logistics Operations : Management Issues in Global Logistics with Offshored Production Systems." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-71908.
Full textReyner, Amy M. "Multi-scale inventory balancing in an extended global supply chain." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37243.
Full textIncludes bibliographical references (p. 68-69).
Dell is a well-known consumer electronics manufacturer that has experienced astounding rates of revenue growth since its inception in 1984. Regarded as a supply chain innovator, Dell has attained success through industry-revolutionizing ideas such as vendor-managed inventory, pull manufacturing, and direct sales. Today, continuance of revenue growth for Dell requires not only rapid innovation, but also rapid geographic and product expansion. Until a few years ago, Dell only had one facility in the United States. All of Dell's US-based systems and processes were constructed to optimize this single factory. Since 1999, Dell has added a number of new facilities in the US - factories and merge centers - for the sake of proximity to customers as well as additional capacity. Also, Dell recently began practicing more product leveling than in the past, producing multiple types of systems at the same factory. Finally, Dell's US supply base has migrated to Asia, as have those of most in the industry. This confluence of complexities has led to a significant increase in instances of material imbalances, whereby any given part has not been distributed to the various sites in accordance with their proportion of actual demand, often resulting in costly expedites from site to site or delayed shipments to customers.
(cont.) Part of the solution to this problem is what Dell has termed "Dynamic Replenishment". As Dell's US supply has shifted from America-based to Asia-based over the past five years, the effective lead time for most ocean-shipped parts has increased from days to several weeks. As a result, the site-level forecast for routing of an ocean shipment is more frequently incorrect by the time it reaches the US, and material imbalances occur. In order to reduce these imbalances, Dynamic Replenishment processes aim to proactively re-route material (if needed, based on campus inventories and forecasts) upon arrival at the US port. This thesis will focus on the tools, information, processes, and organizational roles that are required to ensure proper routing of material at the latest possible juncture in Dell's ocean-network supply chain. Treatment will also be given to the idea that the material balancing problem is one of many that result from Dell's rapid supply chain growth, and some related issues will be examined from this broader perspective. (A note on scope: The content of this thesis is related only to Dell's US-based operations. All history, facts, and comments should be taken in this regard.)
by Amy M. Reyner.
S.M.
M.B.A.
Lee, Sang-Yoon. "Integrated logistics and supply chain management, global sourcing and sustainable competitive advantage." Thesis, Cardiff University, 2005. http://orca.cf.ac.uk/55161/.
Full textRao, Jun M. Eng Massachusetts Institute of Technology. "Improvement on service part supply chain with centralized management and global optimization." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/38288.
Full textIncludes bibliographical references (leaf 43).
This project was performed under the supervision of the global supply chain department of InFocus Corp. The company is having high service costs in the Asia Pacific region and desperate to lower the cost in the reverse supply chain and to improve the service level to its customers. In this thesis report, InFocus' current reverse supply chain networks in different business regions were reviewed and detailed analysis was performed for the Asia Pacific region. The results of the analysis showed that the service part supply chain in the Asia Pacific was inefficient and costly due to redundant echelon, insufficient information sharing and lack of centralized management. A shorter and more centralized supply chain was proposed. A comparison was made and various key performance indicators were used to judge the effectiveness of the improvements. The analysis showed that the proposed supply chain has lower costs, lesser safety stock, and higher service levels. Transportation was also shown to be more flexible and cost effective through the proposed replenishment policies. Strategic 3PL partnership and vendor managed inventory (VMI) were also discussed in the later part of the report. Future work can be devoted in these areas to explore the potential of further improvement in the reverse supply chain.
by Jun Rao.
M.Eng.
Wilson, Prentice D. (Prentice Douglas) 1971. "Managing a global supply chain with durable arm's-length supplier relationships." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/9151.
Full textIncludes bibliographical references (leaves 65-66).
Rapidly changing technology and increased competition have made supply chain management and purchasing more and more critical in determining a companies competitiveness. Many industrial firms spend more than one half of every sales dollar on purchased products, and this percentage has been increasing with recent moves towards downsizing and outsourcing. Consequently, more and more pressure is being placed on materials organizations to cut costs and manage supply chains more efficiently. By developing tools that address two of the biggest issues, this project seeks to aid in the cost cutting and supply chain management efforts. The first tool optimizes product demand allocation among suppliers. The second tool controls inventory levels through more accurate inventory targets. Without proper tools to enable optimal demand allocation among suppliers, companies incur excess procurement costs. Most allocation systems do not take supplier capacity and shipping costs into account when allocating demand. Consequently, overall costs are excessive, because individual supplier capacities and demand is not matched to reduce costs for the supply chain as a whole. Many companies set inventory targets that are unattainable without significant risk, because the targets do not accurately represent requirements. Current targets are derived from models that do not include forecasted demand fluctuations, lead-times to individual plants, or variations in lead · times to plants. Therefore, there is an imbalance in true inventory requirements and estimated inventory requirements.
by Prentis D. Wilson, Jr.
S.M.
Mody, Amil. "Improving the risk identification process for a global supply chain." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/73393.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 116-118).
This thesis describes a proposed risk identification process that is intended to systematically identify potential risks that could materialize within a company's supply chain that would affect component supply. The process is based on a specific situation at Nokia though is intended to extend to other companies that rely extensively on outsourced component manufacturing. An analysis of the current risk identification process at Nokia revealed three areas of potential improvement: the lack of full upstream visibility, the supplier-centric nature of the process and risk reports not fully conveying desired information. Based on a review of existing literature on supply chain risk management and other risk prediction techniques, as well an analysis of the specific situation at Nokia, which has a complex and rapidly-changing supply chain, a new risk identification process was developed. This process consists of two steps: first, mapping out the network structure of the company's supply chain; second, identifying and tracking certain data that could be used as factors to identify potential supply risks. The process proposes a model based on fuzzy logic to aggregate and map the data to highlight potential risks. The thesis also contains a discussion of implementation of the proposed approach, including software requirements as well as organizational roles and responsibilities.
by Amil Mody.
S.M.
M.B.A.
Patel, Sonny. "Forecasting quality in robotic controller supply chain." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/112487.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, in conjunction with the Leaders for Global Operations Program at MIT, 2017.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 53-54).
Between 2017 and 2019, industrial robot installations are estimated to increase by 13% on average per year. As the industrial robot market has grown, so too have customer demands. Many industrial robot manufacturers are in a position to capture this growth by improving in on-time delivery, quality performance, and product offerings. This master's thesis is devoted to providing manufacturers methods for increasing quality performance for robotic controllers. To improve quality performance, we focus on finding the connection between controller quality performance at suppliers, manufacturing, and customer sites. We consider this valuable in the context of a manufacturer's R&D to set operational quality targets and predict the cascade effect in the supply chain. This study includes a deep dive in quality performance and methods to predict future performance. The analysis includes a look at quality metrics in the robot industry. We forecast future performance against these metrics using an available dataset and regression modeling. Because we do not discover strong regression models, we propose dataset statistics to forecast future quality performance. We have 2 recommendations based on our research. Moving forward, we recommend increasing transparency for quality data collection to create a more robust model with stronger prediction capabilities. We also recommend a total cost of quality approach in determining ideal quality metrics.
by Sonny Patel.
M.B.A.
S.M.
alramadin, manal. "Strategies to Mitigate Negative Results of Supply Chain Disruption." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7909.
Full textPark, B. Joon. "A framework for integrating product platform development with global supply chain configuration." Diss., Georgia Institute of Technology, 2001. http://hdl.handle.net/1853/30750.
Full textFalks, Marcia S. "Supply Chain Management Strategies in the Manufacturing Industry." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5856.
Full textNg, Chong Keat. "Inbound supply chain optimization and process improvement." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/81122.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 58).
The primary goal of this project is to evaluate Amazon's inbound supply chain processes and identify improvement opportunities in transportation cost and lead time. Analysis will be focused on defining the current state and evaluating the strengths and weaknesses of the inbound processes. This paper will also include a literature review of the various freight consolidation and vendor coordination strategies in the industry and their impact on cost and lead time. Specific case studies based on actual cost savings programs will be discussed.
by Chong Keat Ng.
M.B.A.
S.M.
Holzer, Akiva. "Enabling supply chain cooperation with information sharing." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54596.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 74-77).
Virtual Business System (VBS) is a system with software and hardware components designed by Raytheon employees to improve operational performance by facilitating and reinforcing lean behavior. It has helped contribute to four years in a row of twenty-percent yearly reductions in costs by providing near real-time metrics information, visibility into the details underlying those metrics, and publishing results to provide accountability for continuous improvement efforts. Originally designed for use in a manufacturing cell, its use has since expanded to include project management, engineering, quality, and other functions. This thesis examines how VBS has contributed to internal alignment at Raytheon and explores whether it can fulfill Raytheon's external supply chain coordination needs as well. VBS was successfully upgraded to allow supplier access over Citrix; the next step is to conduct a pilot implementation to test the system in practice. As a "homegrown" system, VBS can be made to do nearly anything, and in time could fulfill Raytheon's supply chain integration needs. In the near term, additional work is likely to be necessary in the areas of data access control, user interface, and extension from stand-alone system to a peer-to-peer information sharing network. The VBS team will also need to continue gathering executive sponsorship and support in order to motivate the necessary change in business processes. A number of lessons applicable to supply chain integration systems in general can be learned from the success of VBS.
(cont.) These include: the importance of ensuring client control and security of the data; the potential gains made possible by sharing functionality in addition to data; the need to include information about improvement processes when sharing information; and the critical need that the application remain flexible and responsive to change in user needs.
by Akiva Holzer.
S.M.
M.B.A.
Koberg, de la Cruz Esteban. "Developing sustainability in global supply chains: the role of secondary stakeholders." Doctoral thesis, Universitat Ramon Llull, 2021. http://hdl.handle.net/10803/672393.
Full textDesarrollar sostenibilidad en las cadenas de suministro es una preocupación urgente para las empresas. Para abordar estas preocupaciones, las empresas compradoras frecuentemente implementan la gestión sostenible de la cadena de suministro a través de la evaluación y la colaboración con sus proveedores. Sin embargo, la efectividad de la evaluación y colaboración con proveedores para mejorar los resultados ambientales y sociales en cadenas de suministro globales caracterizadas por una gran distancia geográfica entre compradores y proveedores, se encuentra cuestionada. La evidencia anecdótica y la investigación reciente sugieren que públicos de interés secundarios como las ONG o las asociaciones comerciales, que tradicionalmente no se consideran parte de la cadena de suministro, pueden ayudar a las empresas compradoras a desarrollar la sostenibilidad en sus cadenas de suministro globales. El propósito de esta investigación fue explorar el desarrollo de la sostenibilidad en cadenas de suministro globales. Para lograr este objetivo, en primer lugar se llevó a cabo una revisión sistemática de la literatura centrada en los principales elementos estructurales y relacionales que caracterizan la gestión sostenible de la cadena de suministro en cadenas de suministro globales. Los resultados de la revisión sistemática revelan que se requiere mayor investigación respecto a la distancia geográfica y los públicos de interés secundarios. A partir de estos resultados, se llevó a cabo un análisis estadístico de datos secundarios de 186 empresas certificadas como B Corporation para examinar la relación entre la distancia geográfica, colaboración de empresas compradoras con públicos de interés secundarios, y la adopción por parte de la empresa compradora de evaluación y colaboración con proveedores. Los resultados sugieren que la adopción por parte de la empresa compradora de evaluación y colaboración con proveedores es mayor en presencia de mayor distancia geográfica, y que la participación de públicos de interés secundarios modera negativamente esta relación. Con el fin de explorar el rol de los públicos de interés secundarios con mayor profundidad, posteriormente se llevó a cabo una investigación cualitativa basada en un estudio de caso de la cadena de suministro de banano fresco en Costa Rica. Los resultados indican que los públicos de interés secundarios desempeñan roles específicos y operan simultáneamente para desarrollar la sostenibilidad en una cadena de suministro global. Esta investigación contribuye a extender la literatura sobre la gestión sostenible de cadenas de suministro al destacar el papel de los públicos de interés secundarios para desarrollar la sostenibilidad en las cadenas de suministro globales. La investigación también tiene implicaciones para gerentes y legisladores.
Developing sustainability in supply chains is a pressing concern for businesses. To address such concerns buyer firms frequently adopt sustainable supply chain management (SSCM) based on supplier assessment and supplier collaboration. The effectiveness of supplier assessment and supplier collaboration for improving environmental and social outcomes in global supply chains characterized by high geographic distance between buyers and suppliers, however, is increasingly debated. Anecdotal evidence and recent research suggest that secondary stakeholders that are not traditionally considered part of the supply chain, such as NGOs or trade associations, can aid buyer efforts to develop sustainability in their global supply chains (GSCs). The purpose of this research was to explore the development of sustainability in GSCs. To achieve the research goal a systematic literature review focused on the main structural and relational elements that characterize SSCM in GSCs was conducted first. The results of the systematic review suggest that further analysis of geographical distance and of the role of secondary stakeholders is needed for understanding how sustainability can be developed in GSCs. Building on these results, statistical analysis of secondary data from 186 certified B Corporations was then carried out to examine the relationship between geographical distance, secondary stakeholder engagement, and buyer firm adoption of supplier assessment and collaboration for sustainability. Results suggest that buyer adoption of supplier assessment and collaboration is greater in presence of geographic distance, and that secondary stakeholder engagement negatively moderates this relationship. Qualitative research based on a case study of the fresh banana supply chain in Costa Rica was then conducted to explore the role of secondary stakeholders in greater depth. Results suggest that secondary stakeholders play specific roles and operate simultaneously for developing sustainability in the upstream part of the GSC. This research contributes to extending the SSCM literature by highlighting the role of secondary stakeholders for developing sustainability in global supply chains. The research also has implications for managers and policymakers.
Gentiletti, Andrea. "Design and optimization of global distribution supply chain at McCain Foods." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/73383.
Full textCataloged from PDF version of thesis. Vita.
Includes bibliographical references (p. 76-77).
Network design has been successfully used by numerous organizations to achieve supply chain excellence through cost effectiveness and superior utilization of resources. This thesis addresses how network optimization methods can be used to provide guidance in the process of creating a company's global supply chain strategy. In order to demonstrate that this approach can be a source of considerable value for an organization, we collaborated for a period of six and a half months with McCain Foods in the creation of their supply chain strategy plan. In the past McCain has managed its capacity and distribution from a regional perspective. While this method has historically produced good results, the size of the company and the challenges ahead justify now a more global approach. To fully leverage McCain's global scale, we conducted a comprehensive study of the supply chain, analyzing possible scenarios and highlights optimal strategies for future growth plans. For this purpose, we created a global supply chain model using LogicNet Plus, representing the movement of finished products from all French fry plants to all markets. From the analysis of the model, recommendations have been produced for McCain's senior leaders and board, and used in the definition of the 5-year strategic plan. To comply with the tight deadlines of the high-level decision-making process of the organization, the model uses highly aggregated and easily available data, yet it can represent reality with sufficient accuracy. The results of the study clearly show how this kind of analysis is able to provide significant input for the definition of a supply chain strategy, and to highlight opportunities for substantial cost savings in a global supply chain network.
by Andrea Gentiletti.
S.M.
M.B.A.
Vidal, Carlos Julio. "A global supply chain model with transfer pricing and transporatition cost allocation." Diss., Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/24134.
Full textPetersen, Brian J. (Brian Jude). "Reverse supply chain forecasting and decision modeling for improved inventory management." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/80988.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 69-71).
This thesis details research performed during a six-month engagement with Verizon Wireless (VzW) in the latter half of 2012. The key outcomes are a forecasting model and decision-support framework to improve management of VzW's reverse supply chain inventory. The forecasting model relies on a reliability engineering formulation and incorporates a learning component to allow incremental forecast improvement throughout the device lifecycle. The decision-support model relies on Monte Carlo simulations to quantify the uncertainty and risk associated with different inventory management policies. These tools provide VzW stakeholders with a full-lifecycle perspective so that inventory planners can avoid costly end-of-life underages and overages. Prior to this effort, inventory planners at VzW relied on a three month returns forecast despite the fact that customers can return devices more than three years after launch. The decision-support model replaces existing heuristics to improve inventory management. Model efficacy is demonstrated through case studies. For a variety of representative SKUs, the returns forecast model is found to predict cumulative lifecycle returns within 10% using data available six months from launch. Had inventory been managed according to the policies recommended by the decision support model instead of policies from existing heuristics, VzW could have avoided an end-of-life stockout of more than 20,000 devices for a particular SKU.
by Brian J. Petersen.
M.B.A.
S.M.
Méndez, de la Luz Diego A. 1979. "Improving supply chain responsiveness for diesel engine remanufacturing." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/67774.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 71).
Achieving a significant reduction in order-to-shipment lead-time of remanufactured diesel engines can dramatically decrease the amount of finished goods inventory that Caterpillar needs to carry in order to meet its delivery commitments to Cat dealers around the globe. This project was launched to devise ways to hold less finished goods by reducing the order-to shipment lead time for diesel engines. To achieve this goal, a team was formed with representatives of all business units involved in the supply chain. Following the first three steps of a DMAIC methodology, the team used the following techniques and made the consequent findings: (1) Define: using Value Stream Mapping, a first-ever value stream map of the supply chain was developed. This identified gaps and focused efforts on key areas. (2) Measure: using statistical lead time analysis, a Monte Carlo simulation was performed to estimate order-to-shipment lead times for the baseline and optimized scenarios of a build-to-order scheme. This identified an opportunity to reduce lead times by increasing parts inventory. (3) Analyze: an inventory model was developed to quantify the economic implications of reducing lead time by increasing inventories. The results were compared to the savings of holding less finished goods to find out the best lead time reduction scenario. Results show that holding inventories as spare parts to enable a build-to-order strategy is less costly than relying on a build-to-stock strategy, but there is a point of diminishing returns. Our research has shown that having all business units collaborate in the process of overhauling the supply chain is key when looking for results that are optimal for the enterprise as a whole. It has also been observed that, if left unattended, a supply chain can be shaped by decisions that, at best, manage to achieve only local optima. In the worst case, the whole supply chain may evolve into a system that has little to do with the company's strategic goals. These observations highlight the need, and support the recommendation, to have a "process owner" who is responsible for coordinating efforts across the supply chain.
by Diego A. Méndez de la Luz.
S.M.
M.B.A.
Kulling, Karl Christian. "Optimized distribution supply chain for improved customer service." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/99029.
Full textThesis: S.M., Massachusetts Institute of Technology, Engineering Systems Division, 2015. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 54-55).
In an attempt to attract consumers, companies are offering an increasingly wide range of product varieties to cater to each consumers individual needs and desires. This behavior leads to fragmentation of demand that increases supply chain complexity and cost. At Company X, this behavior is also visible. There is a proliferation of product types and sizes as these are increasingly used for product differentiation by both the company and original equipment manufacturers that use its products. This, in turn, lowers demand per product and disaggregates it, resulting in higher variability. Some of Company Xs products that are affected by the changes in demand patterns, and consequently have relatively low demand, are also highly profitable. This relatively small, but increasingly important segment of the market is not well served by the existing supply chain that has been optimized for large, steady flows of products. Service levels for products with the new demand patterns are low, leading to customer dissatisfaction and lost sales. We hypothesize that Company X can improve its customer service, as measured by service level, fill rate, and on time delivery rate, for consumer products by adopting a segmented supply chain. The current supply chain is optimized for products that have a steady and large demand, but it undersupplies products with low or variable demand. A segmented supply chain would allow each segment of products to be served by a supply chain that is optimized to that segments demand characteristics. Traditional manufacturing would provide a low-unit-cost source of products, while a new, agile small-scale manufacturing source would provide a responsive source of products.
by Karl Christian Kulling.
M.B.A.
S.M.
Hwang, David Delchi 1975. "Performance measurement system design for supply chain organizations." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/66076.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 86-89).
This thesis proposes a methodology to create an effective performance measurement system for an interconnected organization. The performance measurement system is composed of three components: a metrics set, a metrics review business process, and a dashboard visualization technique to display the data. If designed according to the proposed methodology, the combination of these three elements produces a performance measurement system which drives behavior, creates accountability, and fosters continuous organizational improvement. The proposed methodology has been demonstrated by its application to a supply planning organization within a major technology manufacturing company. Specifically, the performance measurement system of this supply planning organization was redesigned using the proposed methodology and pilot-tested over the course of a six-month period. First, the metrics set was redesigned based on alignment to strategic objectives and grounded in metrics design fundamentals. Second, the business process to review the organization's metrics and spur action was streamlined and redesigned for maximum impact and engagement. Finally, a visualization dashboard was created to communicate key metrics clearly to all members of the organization. The resulting performance measurement system demonstrates the effectiveness of the proposed methodology and has been adopted as the system-on-record for the organization. Broadly speaking, the principles of performance measurement design provided in this thesis can be applied to other interconnected organizations.
by David Hwang.
S.M.
M.B.A.
Da, Silva Duarté Natalia. "L’insertion des coopératives issues de l’agriculture familiale dans une global value chain : le cas des apiculteurs du Nordeste du Brésil." Thesis, Pau, 2018. http://www.theses.fr/2018PAUU2033/document.
Full textThe difficulties of small farmers go back a long time. Several studies have been developed to solve their main problems. These include small-scale production, obtaining the market for these products, managing their small 'business', acquiring a financial return.The purpose of our thesis is not to transform small farmers to large, this mistake has already been made previously by various public policies in developing countries. Our goal is to provide a way in which they can, even if small, ensuring their quality to improve its product life cycle from production to sale in the market.However, we know that for a small farmer is not easy to enter into the world market individually. The consumer market needs continuous production, in quality and quantity. So, they need to develop collective actions that can insert them into this global supply chain.Why are we talking about the introduction of producers into the world market and not their introduction into local markets? Well, our context is based on small farmers in underdevelopment regions which do Not have the economic capacity to buy their products in the way to ensure the sustainability of their business, so the challenge is; insert farmers into global circuits.In this case, farmers will have a more equitable payment for their production and be able to 'fly on their own', from a capabilities approach, they should look for a form of organization that allows production with characteristics and quality similar, ensuring the packaging and transportation process, in addition to having financial and management potential to conduct negotiations with customers and suppliers. At that moment, we are wondering what is the apropriate legal form “Cooperative” or not.From several case studies we analyze two territories in the Northewest region of Brazil, one (Piauí) and the other (Ceará). We are clear that the management of SCM, support for beekeepers and quality control department are, among others, those that are at the origin of the success of the central cooperative of Piauí
Do, Wondong. "Development of international supply chain strategies to support global sourcing and manufacturing." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/51663.
Full textIncludes bibliographical references (p. 79).
Globalization in sourcing and manufacturing is expected to offer several different kinds of benefits. Globalized companies can produce products at cheaper costs by accessing cheaper resources and they can be close to the local market, so that they can quickly react to the needs of local markets. However, there are risks involved in global expansion. Different countries have different cultures and environments. Political relationships between the countries and global economic challenges may also affect the reliability and the profitability of globalization. Globalization requires goods to travel longer, which in turn pushes up the logistics costs. Among all the challenges, this thesis focuses on the supply chain challenges of globalization and develops the strategies to address those challenges. The thesis will provide framework to help to make international supply chain decisions. Based on this framework and the current Honeywell's environment, it will identify four different improvement opportunities and associated solutions. Each opportunity will be evaluated by appropriate models. The goal of identifying Honeywell's improvement opportunities and evaluating them is to present some structural results for each supply chain option: how the trade-offs of the option can be optimized and in each case, which option works best. In the last part, the thesis will also discuss the implementation challenges. The organizational challenges will be analyzed by using the three lenses and the change management will be discussed.
(cont.) In addition to the organizational challenges, the communication challenges, which become more important in a global environment, will also be discussed. Although these are the challenges faced during the project at Honeywell, many companies that are trying to do global expansion experience same type of challenges. Thus, this discussion will help to address implementation issues that most companies face.
by Wondong Do.
M.B.A.
S.M.
Hughes, Nina(Nina Yuchen). "Reverse logistics supply chain process modeling and simulation." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122581.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2019, In conjunction with the Leaders for Global Operations Program at MIT
Cataloged from PDF version of thesis.
Includes bibliographical references (page 67).
As consumer preferences shift towards online shopping and utilizing their homes as fitting rooms, traditional brick and mortar retailers are faced with the challenge to adapt. Many retailers are experiencing a growing number of returned merchandize, many of which cannot be easily resold to consumers due to various supply chain challenges. This thesis explores the opportunities to improve the consumer returns process and presents methods for modeling the supply chain process for reverse logistics in the retail industry derived from case studies. The model then allows for hypothesis testing. By changing parameters in the model, this thesis further explores the scenarios in which the supply chain process may be improved to increase margin and decrease cost. The primary recommendations include specific modifications to the current reverse supply chain flow, enabling new channels that improve speed and margin, as well as developing the decision tool further for better accuracy and integration into the supply chain.
by Nina Hughes.
M.B.A.
S.M.
M.B.A. Massachusetts Institute of Technology, Sloan School of Management
S.M. Massachusetts Institute of Technology, Department of Civil and Environmental Engineering
Sazdanoff, Nicholas. "Evaluation of postponement in the Drug Product supply chain." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/99037.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2015. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 64-65).
This thesis evaluates the use of postponement in the Drug Product (DP) supply chain at Amgen, which is characterized by highly variable production lead times. The motivation for the use of postponement in the DP supply chain is to reduce the lead time and improve the service level from the manufacturing site to the distribution centers (DCs). Amgen is undergoing a rapid global expansion and is now serving markets that operate on tender (bid) systems that require rapid fulfillment. To compound this challenge, FDA driven requirements have significantly increased the likelihood of generating Non-Conformances (NCs) in DP manufacturing, which in turn increases the production lead time variability. A simulation model was created in Microsoft Excel that uses historic production lead time and demand data to determine postponement levels and simulate performance of the system. Leveraging the simulation model, this thesis demonstrates that utilizing postponement in supply chains with highly variable production lead times can significantly improve service level and diminish customer lead time while potentially reducing global inventory levels.
by Nicholas Sazdanoff.
M.B.A.
S.M.
Haidar, Samer S. M. Massachusetts Institute of Technology. "Supply chain network strategy for consumer medical device introduction." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104310.
Full textThesis: S.M. in Engineering Systems, Massachusetts Institute of Technology, Department of Mechanical Engineering, 2016. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 97-99).
This thesis presents an optimization framework to model the trade-offs in strategic supply chain decision-making for a new product introduction in a real-world setting. The focus of the thesis is on a consumer medical device that Johnson & Johnson's Calibra business will launch in the future. As with any new product introduction, the launch exposes the J&J business to risk and uncertainty. We develop a mixed-integer optimization model to guide the optimal design of a global consumer medical device supply chain network comprising component suppliers, assembly facilities, sterilizers, and distribution centers. The model evaluates strategic decisions over a seven-year time horizon related to the location and capacities of various supply chain facilities and partners, transportation costs, and strategic inventory required to satisfy global demand. We developed a stochastic optimization extension of the model to protect the supply chain decision maker from demand uncertainty. Comparison of the output of the model assuming deterministic demand to a managerial heuristic resulted in total supply chain network cost reductions of 19% - 27%, amounting to hundreds of millions in present-value dollars. The stochastic optimization solution reduces infeasibility related to either not meeting the demand or transportation lead time constraints. The two models presented in this thesis enable J&J supply chain decision makers to gauge the additional costs and benefits of different network design concepts, develop a network strategy that can adapt to uncertain demand, and create a strong strategic foundation for future tactical and operational decisions.
by Samer Haidar.
M.B.A.
S.M. in Engineering Systems
Cummings, Charles R. III (Charles Ronald). "Improving the inbound supply chain through dynamic pickup windows." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90761.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (page 72).
Amazon is one of the world's largest retailers with revenues of $74.5 billion in 2013 and 22% growth over 2012. As Amazon continues to grow and offer greater selection, more products are flowing through an expanding inbound network. While this growth has added complexity for the inbound transportation organization, it has also created opportunities to reduce transportation cost and improve performance. Inbound transportation managed by Amazon currently represents 60% of the company's inbound freight. For this freight, Amazon uses automated shipment-planning systems to select a carrier for all shipments. The systems run once per day, selecting carriers for a set of shipment requests where each vendor has specified a freight ready date of tomorrow. Several inputs are included to achieve a low transportation cost for the network, but the systems are constrained by the vendor's freight ready date. By introducing dynamic pickup windows based on when the freight is needed in the fulfillment centers (FCs), Amazon has the opportunity to reduce transportation cost and mitigate out-of-stock occurrences. A current state analysis revealed that approximately 70% of Amazon's freight was shipped through expensive less-than-truckload and small-parcel methods. While truckload shipments are ideal in transportation, ordering smaller lots more frequently is preferable to maintain high in-stock levels in the FCs while keeping inventory holding costs low. Therefore, Amazon's shipment-planning systems minimize transportation cost by building multi-stop routes to pick up smaller shipments from several vendors before delivering to the FC. The dynamic pickup window solution changes the planning process by relaxing the constraint of tendering a shipment today to a high cost transportation mode if that freight does not need to ship today. If shipment requests are not tendered today and instead sent to tomorrow's pool of requests, two types of consolidation can occur: (1) a single-vendor consolidation and (2) a multi-vendor consolidation. A model was developed to simulate shipment planning on the entire network for one week, resulting in a 2% transportation cost reduction and 4% fewer shipments while protecting in-stock levels. Amazon piloted in late 2013 with success and plans to implement throughout the network in early 2014. While the dynamic pickup window solution is presented with Amazon as the case study, the solution is applicable to any business with stochastic demand and lead time, a large vendor base, and control of managing its inbound transportation.
by Charles R Cummings, III.
M.B.A.
S.M.
Hillstrom, David (David P. ). "Multi-tier supply chain assessment of garment environmental sustainability." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/117965.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, in conjunction with the Leaders for Global Operations Program at MIT, 2018.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 59-62 ).
Li & Fung is a global, leading trading firm that connects manufacturing vendors with retailers. Li & Fung is responsible for the supply of beauty products, furniture, and apparel, with the majority of sales in the apparel category. Li & Fung has developed strong relationships with a large portion of global retailers and maintains a leading market position in the global garment market. Furthermore, Li & Fung leverages a complex supply chain of over 16,000 partner factories across 40 countries. These factories employ hundreds of thousands of workers who perform the difficult work of producing a variety of garments. This large footprint of factories and employees results in an equally large environmental footprint. Although it is well known that the environmental impact is substantial, with researchers stating that the apparel industry is one of the largest global polluters, it has been difficult to quantify the business impact as a whole, let alone the impact of a single garment. Through this internship, the objective was to quantify the environmental impact of factories and products. This quantification will enhance decision-making and arm the business with a toolset to help factories improve and drive down impact in a targeted manner. Furthermore, these quantifications are manifested in product level footprints and factory metrics calculated with the use of internally generated data and external data. The internal data provided much of the backbone for the analysis and its collection was completed through an internally developed, proprietary tool. External data was then gathered to address information gaps in the supply chain. Together this data formed the basis for Li & Fung's Environmental Assessment Tool. This tool provides potential benefits at all levels of the supply chain. In particular, it allows designers and customers to make informed decisions about product attributes that drive environmental impact, factories to compare their environmental impact against an appropriate peer group and make educated decisions, and Li & Fung to quantify their environmental impact and take steps to address environmental hotspots.
by David Hillstrom.
M.B.A.
S.M.
Hardy, Robert (Robert Andrew). "Evaluation of marking technology for risk management in the biopharmaceutical supply chain." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/69212.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 85-86).
Amgen is a leader in the biopharmaceutical industry. It manufacturers and provides human therapeutics that drastically improve lives. Amgen's reputation and brand, its goodwill, is an invaluable asset to its ability to succeed in an increasingly competitive landscape. Because of this, risk management, both in manufacturing and in supply chain arenas, are directly linked to continuing long-term sustainable growth. With an increasingly global market and expanding pipelines, biotechnology companies, like Amgen, face a supply chain challenge to manufacture and distribute products using economically feasible methods that ensure patient safety. Preventing product mix-ups plays a key role in ensuring that safety. Marking nude product that moves intra-Amgen or to contract manufacturers will provide a higher level of confidence that the right product is reaching the patient. Several solutions for marking nude vials and syringes immediately rise to the top of the strata of potential technologies. Despite being promising, each technological solution has key unknowns that must be answered by rigorous labscale testing to provide quantitative data to make the best decision on the future of this process within Amgen. Along with the testing, it is clear that the financial landscape of the different solutions varies a great deal. Each potential solution will be analyzed to determine its capital requirements as well as ongoing costs. Lastly, the solution must be realistic to implement into Amgen's current GMP. And thus, each technology will be evaluated as it relates to the overall complexity of implementation into an already tightly controlled process. From a more macroscopic industry perspective, the FDA, as well as other regulatory agencies, has been discussing this issue for several years. Strategically, biotechnology companies are all hesitant to invest in a particular solution at the moment for fear that the FDA will require a different solution in the near term. In reality, biotechnology companies risk billions in R&D and drug development and are therefore, in a way, naturally risk averse when it comes to their processes and operations. Inventory and manufacturing operations are more driven by risk management than by cost. Of course, the important factor to remember is that risk management is a precursor to drug quality and patient safety. The majority of the risks that are controlled are risks that would either prevent environmental contamination of the drugs or affect the quality of the drugs. Altruistic or not, this has profound long term business strategy implications in an ultra-competitive marketplace where another biotechnology firm would certainly oblige taking market share if Amgen were to suffer a reputation ruining event.
by Robert Hardy.
M.B.A.
S.M.
Noday, Daniel A. (Daniel Alexander). "Supply chain network design to minimize total landed cost." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90793.
Full textThesis: S.M., Massachusetts Institute of Technology, Engineering Systems Division, 2014. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (page 72).
In recent years, markets and supply chains have become increasingly global in nature. Increased competition has driven the need for more efficient and cost-effective supply chain strategies and production methods. Firms have effectively used analytical techniques to develop manufacturing and supply chain solutions at the strategic, tactical, and operational levels. One such analytical technique for assisting in the development of a strategic network design is the use of a supply chain network optimization model. As part of this study, a supply chain network optimization model was implemented for use by an undisclosed company. This company is in the middle of a cultural shift in focus, from that of manufacturing for economies of scale to manufacturing in support of an integrated and efficient supply chain. As part of this transition, the company must develop analytical techniques and tools to support decision-making on questions ranging from strategic to operational in nature. The primary question posed in this study is "How can this company assess supply chain strategies with the goal of minimizing total landed cost?" To address this question, and support strategic discussions on the topic, a supply chain network optimization model was developed using the IBM ILOG LogicNet Plus software package. The model addresses this question by outputting a supply chain network design that minimizes the total landed cost of supplying products to customers. Case studies were conducted to demonstrate the model's ability to inform strategic decision-making. Inputs to the comprehensive total landed cost function were manipulated to show the impacts and tradeoffs associated with the various cost components and to assist in finding robust and sustainable solutions.
by Daniel A. Noday.
M.B.A.
S.M.
Heinz, Michael Pierre. "Network master planning for a global manufacturing company." Thesis, Berlin dissertation.de, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=2839589&prov=M&dok_var=1&dok_ext=htm.
Full textSantomauro, Joanne DeFusco. "An Exploration of the Global Clinical Trial Ancillary Supply Chain and the Drivers of Success During the Pre, In, and Post Phases." Diss., Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/569244.
Full textD.B.A.
Until recently, academic and practitioner research on clinical trial supply chains focused on identifying innovative models and solutions in providing comparator and study drugs to global clinical sites. Due to the expansion of outsourcing efforts by pharmaceutical organizations, newly enacted global laws and regulations, and the continued push to increase the speed at which new drugs gain market approval, a new and extremely complex global “ancillary” supply chain has emerged. This manuscript focuses on the clinical trial ancillary supply chain: a supply chain that develops the end-to-end process resulting in the distribution and quality management of medical products and devices, consumable supplies, and patient giveaways to global clinical trial sites. Based on a series of quantitative analyses, this research assesses the influence of the customer, country, and product on the overall success of the supply chain. Three factors emerged from these analyses as having a direct influence on the clinical trial ancillary supply chain; product characteristics, magnitude (components of size), and stability (components of changes in scope). Part II of this research sought to understand the success of the supply chain by evaluating the moderating effects of knowledge management, organizational culture, therapeutic area, and type of shipment. Assessments of 444 customer and server surveys yielded components of a sense of shared culture, shared communication and transparency, and feeling educated and supported. Quantitative data analysis supported that these components had a moderating influence on success during the pre-trial phase of the supply chain. These research findings provide insight into the internal and external drivers of success within the complex and emergent clinical trial supply chain – a supply chain that helps pharmaceutical organizations bring innovative therapies to market and most important, those patients in need of such therapies to improve or even save their lives.
Temple University--Theses
Markowicz, Federico. "Optimizing order-routing decisions : leveraging omni-channel supply chain fulfillment." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/111492.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, in conjunction with the Leaders for Global Operations Program at MIT, 2017.
Cataloged from PDF version of thesis.
Includes bibliographical references (page 73).
This thesis provides a deep mathematical analysis of the diverse alternatives for routing models considering an Omni-channel supply chain. The natural evolution of supply chains from traditional brick-and-mortar stores to an omni-channel supply chain, encompassing and merging e-commerce together with a multi-channel concept, allows businesses to reach new levels of operational efficiency by leveraging inventory closer to the customer and making decisions on the fly on how to better and more cheaply provide a service/product to the final consumer. The flexibility and benefits, unfortunately, do not come without a certain dose of complexity and further development of the supply chain tactical implementation and systems. New alternatives to fulfill customer orders are available, which require greater screening among the different alternatives. An effective routing model becomes essential to make sure these alternatives are properly considered in order to satisfy both the consumer and retailer objectives, such as on-time delivery of orders, retail stores' service levels, and fulfillment costs.
by Federico Markowicz.
M.B.A.
S.M.
Das, Shouvik. "Multi echelon supply chain design for Amazon private brands." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/126953.
Full textThesis: S.M., Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, in conjunction with the Leaders for Global Operations Program at MIT, May, 2020
Cataloged from the official PDF of thesis.
Includes bibliographical references (page 54).
Retailers across the globe continue to grow their private label portfolio to offer customers an alternative to existing brands. Typically, retailers source private label products directly from manufacturers to remove middlemen from the value chain, thereby capturing greater value and subsequently passing it on to customers. Combined with the growth of e-commerce as the primary method for consumers to shop for products, expanding private label portfolio has made e-retailers to re-think their supply chain. Amazon began its journey in Private-Label Brands (PB) in 2009 with the launch of Amazon Basics. Since then, it has expanded its presence across multiple categories. The majority of these products are imported from Asia-Pacific region (APAC) and require sourcing larger quantities to account for long-lead time between production runs and high variability in demand to maintain competitive costs.
These factors result in PB inventory dwelling for a long period at the Amazon Robotic Fulfilment Centers (FCs), reducing the turns-ratio of expensive storage bins there, which could otherwise be utilized for storing high-velocity products. The growth of PB products raises the need to build more storage space, which is expensive in highly automated robotic FCs. Additionally, since fixed storage cost is proportional to the space occupied in FCs, high 'dwell time' translates to high storage cost. To increase utilization of FC storage bins, the Inbound Supply Chain Team plans to build a low-cost upstream storage (LCS1) to supply the FCs and store excess PB inventory there. Alternatively, Amazon can also use its third party storage center in APAC, another low-cost storage node (LCS2), after sourcing PB products from manufacturers in Asia before shipping to regional markets in US, EU, Japan etc.
This could provide an opportunity for inventory savings from risk pooling by optimizing inventory storage across various nodes in the supply chain. Using multi-echelon inventory optimization techniques, this thesis explores the tradeoffs between using low-cost storage node close to end customers in the US (LCS1) versus that close to manufacturing source in APAC (LCS2). The objective of the thesis is to find the optimal inventory placement strategy across three storage points - FCs, LCS1 in US, and LCS2 in APAC - to achieve the best-in-class customer experience (InStock availability) at minimal inventory storage cost.
by Shouvik Das.
M.B.A.
S.M.
M.B.A. Massachusetts Institute of Technology, Sloan School of Management
S.M. Massachusetts Institute of Technology, Department of Civil and Environmental Engineering
Li, Bo. "Supply Chain Inventory Management with Multiple Types of Customers: Motivated by Chinese Pharmaceutical Supply Chains among Others." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1371136834.
Full textBen-Zvi, Noa. "(OR)² : operations research applied to operating room supply chain." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/91096.
Full textThesis: M.B.A., Massachusetts Institute of Technology, Sloan School of Management, 2014. In conjunction with the Leaders for Global Operations Program at MIT.
Cataloged from PDF version of thesis.
Includes bibliographical references (page 63).
Massachusetts General Hospital (MGH) is ranked as the top hospital in New England and second nation-wide. It is also the largest hospital in New England; it uses an average of 58 operating rooms, where approximately 150 surgical procedures are performed daily. Management of surgical supplies is a critical component of the processes supporting this infrastructure. Specifically, ensuring the right equipment and supplies are available at the right time is critical for the efficiency and quality outcomes of each of the procedures. The materials management group handles over 10,000 unique items, purchased from more than 400 vendors. The majority (60-70%) of disposable supplies are ordered through Owens & Minor, a medical and surgical supplies distributor. The supplies are stored in multiple locations throughout the hospital, including two central locations as well as carts and cabinets on the surgical floors and in the operating rooms. The work described in this thesis focuses on the inventory management of disposable surgical supplies, where the current system design has inefficiencies in the inventory levels and location of items. Using a data-driven approach, based on historical demand, we calculate base stock levels by item that maintain three days of inventory at a 99 percent service level. In addition, we suggest a methodology to support decisions on inventory locations of the different items. Implementation of the recommended changes is estimated to result in savings of 30-40% in inventory levels (and space), corresponding to a one time saving of $700,000-$900,000, depending on the implementation scenario. In addition, the reduction in inventory levels can be translated to future savings in inventory holding costs at an estimated 40% rate, leading to a saving of roughly $300,000 annually.
by Noa Ben-Zvi.
S.M.
M.B.A.
Giacomantonio, Robert. "Multi-echelon inventory optimization in a rapid-response supply chain." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/80995.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 91-92).
The motivation for multi-echelon supply chain management at Nike is to more cost-effectively accommodate customer-facing lead time reduction in the rapid-response replenishment business model. Multi-echelon inventory management, as opposed to a traditional finished-goods only philosophy, provides two clear benefits to a make-to-stock supply chain: first, it increases flexibility through staging calculated work-in-process inventory buffers at critical supply chain links and allowing postponed identification of finished goods; second, inventories held as work-in- process are typically carried at lower cost than finished goods. This thesis details the completion of a project intended to improve Nike's ability to determine optimal inventory levels by balancing cost and service level tradeoffs in a multi-echelon-enabled environment. The goal is to develop an inventory modeling methodology for Nike's supply chain data architecture specifically to evaluate the hypothesis that multi-echelon inventory management will present only limited opportunity for cost reduction in offshore, long lead time make-to-stock supply chains. To directly asses the hypothesis, Llamasoft's Supply Chain Guru optimization software will be deployed to create an inventory optimization model for a specific family of apparel products sold as part of Nike's replenishment offering in North America. The modeling results confirm the hypothesis that multi-echelon inventory management offers little value to the current offshore supply chain. Sensitivity and scenario analysis is utilized to identify significant inventory drivers, areas for substantial improvement, and profitable opportunities for multi-echelon inventory management.
by Robert Giacomantonio.
S.M.
M.B.A.
Oti, Olufemi (Olufemi Oluwole). "Hub and spoke network design for the inbound supply chain." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81007.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 68-69).
Amazon is one of the world's leading retailers. At the core of Amazon's business model is providing consumers with endless selection, and as a result, the large number of vendors used to provide that selection greatly increases the complexity and cost of operating the inbound supply chain. This growth has also created many opportunities for the company to leverage its size and scale to lower transportation costs and improve supply chain flexibility. This project explores implementing load consolidation strategies within the "Hub and Spoke" distribution framework to provide these benefits. As -65% of total unit volume from the inbound transportation program managed by Amazon is shipped as costly less-than-truckload (LTL) or small-parcel (SP) freight, there are significant opportunities to use consolidation hubs throughout the inbound network to reduce spend on LTL and SP in favor of more cost effective full truckload (TL) shipments. To evaluate the opportunity and provide the inbound team with a useful strategic planning tool, a comprehensive network optimization model was targeted as a project deliverable. After researching the current state of the inbound transportation network through departmental interviews and visits to carrier hubs and fulfillment centers, key inputs were identified to feed the model. The mixed integer program solution uses these inputs to minimize total inbound transportation cost for the network subject to expected transit time performance targets by choosing what consolidation hubs and destination lanes freight should be routed to. Using a data-set of shipments originating in the Southwestern geography, an average saving of 13.7% on annual LTL and SP spend was projected by routing 37% of freight volume through consolidation hubs. Results showed freight density as an important driver in savings. In areas with more originating freight, outbound full truckloads can be filled more readily and hence consolidation opportunities can be taken advantage of more often. This tool and the supporting analyses will help the inbound transportation organization uncover more cost saving opportunities in routing freight through its growing network. In addition to financial cost savings, the strategy will increase supply chain flexibility, reduce environmental impact, and can help increase Amazon's control over the end-to-end inbound transportation network.
by Olufemi Oti.
S.M.
M.B.A.