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Relevant bibliographies by topics / Global suppressor

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Academic literature on the topic 'Global suppressor'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

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Journal articles on the topic "Global suppressor"

1

Chattopadhyay, Gopinath, Jayantika Bhowmick, Kavyashree Manjunath, Shahbaz Ahmed, Parveen Goyal, and Raghavan Varadarajan. "Mechanistic insights into global suppressors of protein folding defects." PLOS Genetics 18, no. 8 (2022): e1010334. http://dx.doi.org/10.1371/journal.pgen.1010334.

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Most amino acid substitutions in a protein either lead to partial loss of function or are near neutral. Several studies have shown the existence of second-site mutations that can rescue defects caused by diverse loss of function mutations. Such global suppressor mutations are key drivers of protein evolution. However, the mechanisms responsible for such suppression remain poorly understood. To address this, we characterized multiple suppressor mutations both in isolation and in combination with inactive mutants. We examined six global suppressors of the bacterial toxin CcdB, the known M182T gl

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Shortle, David, and Beth Lin. "GENETIC ANALYSIS OF STAPHYLOCOCCAL NUCLEASE: IDENTIFICATION OF THREE INTRAGENIC "GLOBAL" SUPPRESSORS OF NUCLEASE-MINUS MUTATIONS." Genetics 110, no. 4 (1985): 539–55. http://dx.doi.org/10.1093/genetics/110.4.539.

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ABSTRACT A collection of 77 unique missense mutations distributed across the gene encoding staphylococcal nuclease (nuc) has been assembled. These mutations were induced by random gap misrepair mutagenesis of the cloned gene and were identified in E. coli transformants expressing reduced levels of nuclease activity. Four nuc - mutations which alter amino acid residues at positions outside of the active site region of the enzyme were submitted to a second round of mutagenesis, and characterization of several independent NUC+ isolates lead to the identification of three second-site suppressor mu

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Herring, Christopher D., and Frederick R. Blattner. "Global Transcriptional Effects of a Suppressor tRNA and the Inactivation of the Regulator frmR." Journal of Bacteriology 186, no. 20 (2004): 6714–20. http://dx.doi.org/10.1128/jb.186.20.6714-6720.2004.

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ABSTRACT Expression of an amber suppressor tRNA should result in read-through of the 326 open reading frames (ORFs) that terminate with amber stop codons in the Escherichia coli genome, including six pseudogenes. Abnormal extension of an ORF might alter the activities of the protein and have effects on cellular physiology, while suppression of a pseudogene could lead to a gain of function. We used oligonucleotide microarrays to determine if any effects were apparent at the level of transcription in glucose minimal medium. Surprisingly, only eight genes had significantly different expression in

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Baroni, T. E., T. Wang, H. Qian, et al. "A global suppressor motif for p53 cancer mutants." Proceedings of the National Academy of Sciences 101, no. 14 (2004): 4930–35. http://dx.doi.org/10.1073/pnas.0401162101.

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Cheng, Chin Leng, Michael K. Wong, and Mark Hochstrasser. "Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects." Molecular Biology of the Cell 32, no. 20 (2021): ar6. http://dx.doi.org/10.1091/mbc.e21-04-0178.

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We identified negative salt tolerance 1 (Nst1) as a dosage suppressor of the temperature sensitivity and proteasome assembly defects in multiple base mutants. Both endogenous and overexpressed Nst1 could localize to processing bodies. Nst1 overexpression inhibited global protein translation that in turn suppressed aggregation and proteasome assembly defects in base assembly mutants.

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Csink, A. K., R. Linsk, and J. A. Birchler. "Mosaic suppressor, a gene in Drosophila that modifies retrotransposon expression and interacts with zeste." Genetics 136, no. 2 (1994): 573–83. http://dx.doi.org/10.1093/genetics/136.2.573.

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Abstract A newly identified locus in Drosophila melanogaster, Mosaic suppressor (Msu), is described. This gene modifies the expression of white-apricot (wa), which is a copia retrotransposon-induced allele of the white gene. In addition to suppressing wa in a mosaic fashion, this mutation suppresses or enhances the expression of several other retrotransposon induced white alleles. Mutations in Msu alter copia transcript abundance and may regulate the expression of several other retrotransposons. While each of the two Msu isolates is homozygous lethal, heteroallelic escapers occur at a low freq

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Nahar, Rahul, Parham Ramezani-Rad, Sinisa Dovat, Maike Buchner, Thomas G. Graeber, and Markus Muschen. "Mechanisms of Ikaros-Mediated Tumor Suppression." Blood 118, no. 21 (2011): 408. http://dx.doi.org/10.1182/blood.v118.21.408.408.

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Abstract Abstract 408 Background: The Ikaros (IKZF1) tumor suppressor is deleted in >80% of the cases of Ph+ ALL. While Ikaros cooperates with pre-B cell receptor signaling to induce cell cycle exit in Ph+ ALL (Trageser et al., J Exp Med, 2009), the mechanism of Ikaros-mediated tumor suppression is poorly understood. Here we report on a series of genetic experiments that show that Ikaros (i) interferes with key survival pathways downstream of the BCR-ABL1 kinase, (ii) inhibits leukemia cell proliferation through interaction with the pre-B cell receptor signaling pathway and (iii) activates

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Irie, K., K. Yamaguchi, K. Kawase, and K. Matsumoto. "The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes." Molecular and Cellular Biology 14, no. 5 (1994): 3150–57. http://dx.doi.org/10.1128/mcb.14.5.3150-3157.1994.

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The STE4 gene encodes the beta subunit of a heterotrimeric G protein that is an essential component of the pheromone signal transduction pathway. To identify downstream component(s) of Ste4, we sought pseudo-revertants that restored mating competence to ste4 mutants. The suppressor mot2 was isolated as a recessive mutation that restored conjugational competence to a temperature-sensitive ste4 mutant and simultaneously conferred a temperature-sensitive growth phenotype. The MOT2 gene encodes a putative zinc finger protein, the deletion of which resulted in temperature-sensitive growth, increase

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Irie, K., K. Yamaguchi, K. Kawase, and K. Matsumoto. "The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes." Molecular and Cellular Biology 14, no. 5 (1994): 3150–57. http://dx.doi.org/10.1128/mcb.14.5.3150.

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The STE4 gene encodes the beta subunit of a heterotrimeric G protein that is an essential component of the pheromone signal transduction pathway. To identify downstream component(s) of Ste4, we sought pseudo-revertants that restored mating competence to ste4 mutants. The suppressor mot2 was isolated as a recessive mutation that restored conjugational competence to a temperature-sensitive ste4 mutant and simultaneously conferred a temperature-sensitive growth phenotype. The MOT2 gene encodes a putative zinc finger protein, the deletion of which resulted in temperature-sensitive growth, increase

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Huang, W., and T. Palzkill. "A natural polymorphism in -lactamase is a global suppressor." Proceedings of the National Academy of Sciences 94, no. 16 (1997): 8801–6. http://dx.doi.org/10.1073/pnas.94.16.8801.

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Dissertations / Theses on the topic "Global suppressor"

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Freter, Jan Rasmus Gerhard. "Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation." Kyoto University, 2011. http://hdl.handle.net/2433/135373.

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Mäkiranta, M. (Minna). "EEG and BOLD-contrast fMRI in brain:cerebrovascular reactivity, suppression of neuronal activity, global and local brain injury." Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274296.

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Abstract The purpose of the present study was to gain more insight into the blood oxygen level-dependent (BOLD)-contrast functional MRI (fMRI) in the brain and its connection to EEG, both in global and local scales of their temporal and spatial relations. BOLD signal changes were studied during hyperventilation (HV) induced EEG reactivity of intermittent rhythmic delta activity (IRDA). The BOLD signal in gray matter decreased 30% more in subjects with IRDA (N = 4) than in controls (N = 4), during the first two minutes of HV. This difference disappeared during IRDA in EEG. BOLD signal changes

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Gabriel, André Filipe Gonçalves. "Suppression therapy of ß-thalassemia using Kanamycin and Gentamicin." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/17790.

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Mestrado em Biologia Molecular e Celular<br>As mutações nonsense são mutações pontuais que originam codões de terminação prematura (PTCs). A expressão de genes portadores de PTCs pode levar à síntese de proteínas truncadas. As proteínas truncadas caracterizam-se por serem menores e, na maioria das vezes, não possuem função biológica, apesar de poderem ter funções deletérias para a célula. Em condições normais, transcritos portadores de PTCs são degradados rapidamente através do processo de nonsense mediated mRNA decay (NMD). Quando um PTC atinge o sítio A ribossomal, os fatores de terminação

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Hérodin, Francis. "Contribution a l'etude des effets d'une reaction inflammatoire et d'une irradiation gamma ou neutron-gamma globale chez la souris." Paris 6, 1988. http://www.theses.fr/1988PA066295.

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Un modele de granulome inflammatoire induit chez la souris par injection souscutanee de microbilles de polyacrylamide est utilise pour etudier la physiopathologie de souris soumises, avant ou apres l'induction du processus inflammatoire local, a une exposition globale a des radiations ionisantes. L'effet suppresseur des radiations ionisantes. Une reaction inflammatoire locale induite depuis 24 h s'accompagne d'un effet radioprotecteur important, qui pourrait etre partiellement explique par une stimulation notable de la myelopoiese

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Desai, Megha. "Structural and Functional Characterization of the MBD2-NuRD Co-Repressor Complex." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3617.

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The MBD2-NuRD co-repressor complex is an epigenetic regulator of the developmental silencing of embryonic and fetal β-type globin genes in adult erythroid cells as well as aberrant methylation-dependent silencing of tumor suppressor genes in neoplastic diseases. Biochemical characterization of the MBD2-NuRD complex in chicken erythroid cells identified RbAp46/48, HDAC1/2, MTA1/2/3, p66α/β, Mi2α/β and MBD2 to comprise this multi-protein complex. In the work presented in Chapter 2, we have pursued biophysical and molecular studies to describe a previously uncharacterized domain of human MBD2 (MB

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Bhowmick, Jayantika. "CcdB : Stability, folding and application to design novel antibacterials." Thesis, 2020. https://etd.iisc.ac.in/handle/2005/5134.

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The primary amino acid sequence typically dictates the ultimate conformation of the protein. Mutations in the sequence demonstrate neutral, positive or negative effects on the structure-function relationship of the protein. Destabilising mutations often reduce the soluble levels of the protein in vivo, leading to complete or partial loss of its function. Global suppressors are diverse compensatory mutations that can alleviate the detrimental effects of multiple destabilised, inactive mutants, despite being physically distant from the site of the original inactive mutations. The molecular mecha

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Wu, Chi Sheng, and 吳啟生. "Global Analysis of Methylated Genes in Gastric Cancer by Differential Methylation Hybridization and CpG DNA Microarray and Identification of Glutamate receptor, ionotropic, kainate 2 as a Potential Tumor Suppressor Gene in Gastric Cancer." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/64139597679182429359.

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博士<br>長庚大學<br>生物醫學研究所<br>98<br>Abstract Aberrant DNA methylation is considered as a major mechanism for silencing tumor suppressor genes in gastric cancer. Here, we used CpG microarray and differential methylation hybridization (DMH) strategies to identify potential tumor suppressor genes, and recovered glutamate receptor, ionotropic, kainate 2 (GRIK2) as a novel epigenetic target in gastric cancer. Additional experiments revealed that the promoter region of GRIK2 was hypermethylated in three out of the four tested gastric cancer cell lines, and its expression was restored by treatment of cel

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Lu, Yen-Jung, and 陸燕榮. "Global Screening of Methylated Genes in Gastric Cancer by Differential Methylation Hybridization and CpG DNA Microarray and Identification of Low Density Lipoprotein Receptor-Related Protein 1B as a Potential Tumor Suppressor Gene in Gastric Cancer." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/93497197014267446088.

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博士<br>國立陽明大學<br>微生物及免疫學研究所<br>98<br>Gastric cancer is the second most common cancer worldwide, while in Taiwan it is the fifth leading cause of cancer-related death. Several factors have been implicated in the development of gastric cancer, including chromosomal instability, genetic and epigenetic alterations, Helicobacter pylori infection, and environmental factors such as diet and smoking. Among them, the aberrant methylation of CpG dinucleotides has been reported during tumorigenesis in gastric cancer. In this study, we used CpG island microarray and differential methylation hybridization (

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Zhang, Peng. "An investigation of interocular suppression with a global motion task." Thesis, 2012. http://hdl.handle.net/10012/7128.

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Abstract Purpose: Interocular inhibitory interactions appear to underlie the establishment of ocular dominance. The inhibitory effect leads to suppression of the non dominant eye in certain conditions. While these processes are not fully understood, the relative differences in image contrast appear to be fundamental. By titrating the relative contrast presented to each eye, a balance in the relative inhibitory effects of each eye can be defined. This research looked at whether the interocular contrast ratio at perceptual balance could be used as an index of the ocular dominance in binocular n

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Wang, Chia-Hung, and 王嘉宏. "Global Screening of Antiviral Genes that Suppress Baculovirus Transgene Expression in Mammalian Cells." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/c48yu9.

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博士<br>國立陽明大學<br>生命科學系暨基因體科學研究所<br>105<br>Although baculovirus has been used as a safe and convenient gene delivery vector in non-mammalian host cells, baculovirus-mediated transgene expression is less effective in various mammalian cell lines. Identification of the negative regulators in host cells is necessary to improve baculovirus-based expression systems. Here, we performed high-throughput shRNA library screening, targeting 176 antiviral innate immune genes, and identified 43 host restriction factor genes in a human A549 lung carcinoma cell line. Among them, suppression of receptor interac

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Books on the topic "Global suppressor"

1

Burson, Jeffrey D., and Jonathan Wright, eds. The Jesuit Suppression in Global Context. Cambridge University Press, 2015. http://dx.doi.org/10.1017/cbo9781139344135.

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J, Blakeslee Richard, and United States. National Aeronautics and Space Administration., eds. Comment on "Current budget of the atmospheric electric global circuit" by Heinz W. Kasemir. National Aeronautics and Space Administration, 1996.

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United States. Congress. House. Committee on International Relations. Subcommittee on Asia and the Pacific, ed. The Internet in China: A tool for freedom or suppression? : joint hearing before the Subcommittee on Africa, Global Human Rights, and International Operations and the Subcommittee on Asia and the Pacific of the Committee on International Relations, House of Representatives, One Hundred Ninth Congress, second session, February 15, 2006. U.S. G.P.O., 2006.

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Beyond suppression: Global perspectives on youth violence. Praeger, 2011.

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Jesuit Suppression in Global Context: Causes, Events, and Consequences. University of Cambridge ESOL Examinations, 2015.

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Wright, Jonathan, and Jeffrey D. Burson. Jesuit Suppression in Global Context: Causes, Events, and Consequences. Cambridge University Press, 2015.

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Wright, Jonathan, and Jeffrey D. Burson. Jesuit Suppression in Global Context: Causes, Events, and Consequences. Cambridge University Press, 2015.

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Taylor, Natalie Greene, Karen Kettnich, Ursula Gorham, and Paul T. Jaeger, eds. Libraries and the Global Retreat of Democracy: Confronting Polarization, Misinformation, and Suppression. Emerald Publishing Limited, 2021. http://dx.doi.org/10.1108/s0065-2830202150.

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Jaeger, Paul T., Natalie Greene Taylor, Ursula Gorham, and Karen Kettnich. Libraries and the Global Retreat of Democracy: Confronting Polarization, Misinformation, and Suppression. Emerald Publishing Limited, 2021.

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Jaeger, Paul T., Natalie Greene Taylor, Ursula Gorham, and Karen Kettnich. Libraries and the Global Retreat of Democracy: Confronting Polarization, Misinformation, and Suppression. Emerald Publishing Limited, 2021.

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Book chapters on the topic "Global suppressor"

1

Shardina, Kseniya, Valeriya Timganova, Mariya Bochkova, and Sofya Uzhviyuk. "Generation of Human Myeloid-Derived Suppressor Cells from CD11b+ Cells in Vitro." In Science and Global Challenges of the 21st Century – Innovations and Technologies in Interdisciplinary Applications. Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-28086-3_49.

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Clarke, Colin. "Establishment of the Colonial Empire: Sugar-Slave Plantations, White Exploitation, and Slave Suppression." In Global Diversities. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-55544-2_2.

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Crowell, Claudia S., and Kathleen Malee. "Neurocognition in Viral Suppressed HIV-Infected Children." In Global Virology II - HIV and NeuroAIDS. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7290-6_11.

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Montana, Ismael M. "Slavery in the Middle East and North Africa." In The Palgrave Handbook of Global Slavery throughout History. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-13260-5_26.

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AbstractIn the early 1840s and following the abolition of the trans-Atlantic slave trade by several European nations and the United States, European humanitarians—particularly the British—embarked on an earnest campaign to outlaw the vigorous enslaving activities thriving in the Middle East and North Africa. This chapter examines the extent to which the marked increase of enslavement activities and their suppression through the pressure of European abolitionism fits into the saga of the nineteenth-century transformation processes characterized by the rise of European domination of the region.

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van Ede, Yolanda. "Sounding Contestation, Silent Suppression: Cosmopolitics and Gender in Japanese Flamenco." In Dance Ethnography and Global Perspectives. Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137009449_9.

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Löfroth, Therese, Tone Birkemoe, Ekaterina Shorohova, et al. "Deadwood Biodiversity." In Advances in Global Change Research. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-15988-6_6.

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AbstractDeadwood is a key component for biodiversity and ecosystem services in boreal forests; however, the abundance of this critical element is declining worldwide. In natural forests, deadwood is produced by tree death due to physical disturbances, senescence, or pathogens. Timber harvesting, fire suppression, and salvage logging reduce deadwood abundance and diversity, and climate change is expected to bring further modifications. Although the effects of these changes are not yet fully understood, restoring a continuous supply of deadwood in boreal forest ecosystems is vital to reverse the

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Lenihan, James M., and Dominique Bachelet. "Historical Climate and Suppression Effects on Simulated Fire and Carbon Dynamics in the Conterminous United States." In Global Vegetation Dynamics. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119011705.ch2.

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Wagg, Stephen. "The soul of a nation, long suppressed?" In Cricket: A Political History of the Global Game, 1945–2017. Routledge, 2017. http://dx.doi.org/10.4324/9781315733210-7.

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Mishra, Bharat, Archita Tiwari, and Shrishti Mishra. "Metabolic Changes and Immunity Suppression Parameters as Biomarkers of Environmental Pollutants." In Biomonitoring of Pollutants in the Global South. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1658-6_20.

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De Fabo, E. C., and F. P. Noonan. "Ultraviolet-Induced Immune Suppression and its Relationship to Statospheric Ozone Depletion." In The Role of the Stratosphere in Global Change. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78306-7_27.

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Conference papers on the topic "Global suppressor"

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DiOttavio, James, Joseph Andrews, Russ Altieri, and William Welsh. "Ground and Flight Testing of a Hub Mounted Vibration Suppression System." In Vertical Flight Society 70th Annual Forum & Technology Display. The Vertical Flight Society, 2014. http://dx.doi.org/10.4050/f-0070-2014-9489.

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The performance of a new vibration control system consisting of a prototype dual-frequency Hub Mounted Vibration Suppressor (HMVS) is described. Bench tests were conducted at a LORD Corp. test facility on a CH-3 fuselage and lead to a flight test conducted on a UH-60A BLACK HAWK helicopter at the AATD flight test facility in Ft. Eustis, VA. During bench and flight test, the HMVS was used to actively nullify all fuselage N/rev vibrations due to in-plane vibratory hub loads in absence of all other vibration suppression systems, both passive and active. A direct comparison against the existing pa

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Qin, Qiaomeng, Erfan Dilfanian, Youmin Zhang, Yufei Fu, Hamza Benzerrouk, and Hakim Guiddir. "Unmanned Aerial-Ground Systems for Wildfire Detection, Global Localization and Suppression." In 2025 33rd Mediterranean Conference on Control and Automation (MED). IEEE, 2025. https://doi.org/10.1109/med64031.2025.11073311.

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Chai, Guang, Zhibin Yu, Thomas Wagner, Xiaofeng Wu, and Giuseppe Caire. "Discrete Codebook Synthesis for Self-interference Suppression based on Fractional Programming and Spherical Search." In GLOBECOM 2024 - 2024 IEEE Global Communications Conference. IEEE, 2024. https://doi.org/10.1109/globecom52923.2024.10901539.

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Men, Wei, Jun Du, Jintao Wang, Xiangwang Hou, Yong Ren, and Dusit Niyato. "Design of ISAC Waveform and Multiple-Access Interference Suppression Receiver for Underwater Acoustic Sensor Networks." In GLOBECOM 2024 - 2024 IEEE Global Communications Conference. IEEE, 2024. https://doi.org/10.1109/globecom52923.2024.10901438.

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Zhang, Yufan, Xu Zhu, Jie Cao, and Yufei Jiang. "Far-Field Uplink Oblique Projection for Near-Field External Passive Intermodulation Suppression in Massive MIMO Systems." In GLOBECOM 2024 - 2024 IEEE Global Communications Conference. IEEE, 2024. https://doi.org/10.1109/globecom52923.2024.10901341.

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CHIBA, NATSUKO, and LEIZHEN WEI. "ANALYSIS OF TUMOR SUPPRESSOR GENE USING MOLECULAR IMAGING FOR PERSONALIZED MEDICINE." In Proceedings of the Tohoku University Global Centre of Excellence Programme. PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO., 2009. http://dx.doi.org/10.1142/9781848163539_0037.

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Chondro, Peter, and Shanq-Jang Ruan. "Low order SSIM-based pixel dimming algorithm with weighted high frequency spectrum suppressor for AMOLED displays." In 2017 IEEE 6th Global Conference on Consumer Electronics (GCCE). IEEE, 2017. http://dx.doi.org/10.1109/gcce.2017.8229186.

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Bhardwaj, Anjana, Zhenlin Ju, Harpreet Singh, Matthew Embury, Jing Wang, and Isabelle Bedrosian. "Abstract 773: A global increase in miRNAs and a concomitant decrease in tumor suppressor pathways define preneoplastic transition in TNBC." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-773.

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Bhardwaj, Anjana, Zhenlin Ju, Harpreet Singh, Matthew Embury, Jing Wang, and Isabelle Bedrosian. "Abstract 773: A global increase in miRNAs and a concomitant decrease in tumor suppressor pathways define preneoplastic transition in TNBC." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-773.

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Nikolić, Nenad. "PROBLEM IDENTITETA NACIONALNE KNjIŽEVNOSTI U MEĐUNARODNOM KONTEKSTU." In IDENTITETSKE promene: srpski jezik i književnost u doba tranzicije. University of Kragujevac, Faculty of Edaucatin in Jagodina, 2022. http://dx.doi.org/10.46793/zip21.025n.

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The paper analyses the global tendency of conceptualizing transnational and regional literature in order to suppress national literatures at first, and then to completely replace them. The analysis is based on History of the Literary Cultures of East-Central Europe: Junctures and disjunctures in the 19th and 20th centuries (Eds. M. Cornis-Pope and J. Neubauer, Vol. I 2004, Vol. II 2006, Vol. III 2007, Vol. IV 2010). The tendency to replace national literatures with the transnational one is depicted within the framework of broader cultural, social, and political circumstances. Based on the ideo

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Reports on the topic "Global suppressor"

1

Chejanovsky, Nor, and Suzanne M. Thiem. Isolation of Baculoviruses with Expanded Spectrum of Action against Lepidopteran Pests. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7586457.bard.

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Our long-term goal is to learn to control (expand and restrict) the host range of baculoviruses. In this project our aim was to expand the host range of the prototype baculovirus Autographa cali/arnica nuclear polyhedrosis virus (AcMNPV) towards American and Israeli pests. To achieve this objective we studied AcMNPV infection in the non-permissive hosts L. dispar and s. littoralis (Ld652Y and SL2 cells, respectively) as a model system and the major barriers to viral replication. We isolated recombinant baculoviruses with expanded infectivity towards L. dispar and S. littoralis and tested their

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Powell, Andrew. 2013 Latin American and Caribbean Macroeconomic Report: Rethinking Reforms: How Latin America and the Caribbean Can Escape Suppressed World Growth. Inter-American Development Bank, 2013. http://dx.doi.org/10.18235/0005765.

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Global growth projections have waned since last year and growth may be suppressed below potential for several years to come. Lower global growth will, all things being equal, imply lower growth in Latin America and the Caribbean. At the same time, clear limits to the potential use of monetary and fiscal policy measures pose another constraint. Consequently, countries should consider further structural reform measures to enhance economic prospects and to escape suppressed global growth. If all countries pursue reforms to enable growth to accelerate by 1.5% on average, then the effect on the reg

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Doo, Johnny. Unsettled Issues Concerning eVTOL for Rapid-response, On-demand Firefighting. SAE International, 2021. http://dx.doi.org/10.4271/epr2021017.

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Recent advancements of electric vertical take-off and landing (eVTOL) aircraft have generated significant interest within and beyond the traditional aviation industry, and many novel applications have been identified and are in development. One promising application for these innovative systems is in firefighting, with eVTOL aircraft complementing current firefighting capabilities to help save lives and reduce fire-induced damages. With increased global occurrences and scales of wildfires—not to mention the issues firefighters face during urban and rural firefighting operations daily—eVTOL tec

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Bermingham, Rowena. International affairs and COVID-19: What are experts concerned about? Parliamentary Office of Science and Technology, 2020. http://dx.doi.org/10.58248/hs10.

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Over 1,100 experts have shared with us their concerns about COVID-19 and COVID-impacted areas in the immediate and longer term future. This report outlines concerns about international affairs. Experts are concerned about how the Coronavirus outbreak might affect relations between countries, as suppression strategies drift. This could create international tensions and lead to a rise in populism. There are also concerns about how criticism of the UK response might impact the the country's global position. Experts are also concerned about a lack of international cooperation. They worry that the

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Sionov, Edward, Nancy Keller, and Shiri Barad-Kotler. Mechanisms governing the global regulation of mycotoxin production and pathogenicity by Penicillium expansum in postharvest fruits. United States Department of Agriculture, 2017. http://dx.doi.org/10.32747/2017.7604292.bard.

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The original objectives of the study, as defined in the approved proposal, are: To characterize the relationship of CreA and LaeA in regulation of P T production To understand how PacC modulates P. expansumpathogenicity on apples To examine if other secondary metabolites are involved in virulence or P. expansumfitness To identify the signaling pathways leading to PAT synthesis Penicilliumexpansum, the causal agent of blue mould rot, is a critical health concern because of the production of the mycotoxinpatulin (PAT) in colonized apple fruit tissue. Although PAT is produced by many Penicilliums

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Yilmaz, Ihsan, Ali Mamouri, Nicholas Morieson, and Muhammad Omer. The Transnational Diffusion of Digital Authoritarianism: From Moscow and Beijing to Ankara. European Center for Populism Studies (ECPS), 2025. https://doi.org/10.55271/rp0098.

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This report examines how Turkey has become a paradigmatic case of digital authoritarian convergence through the mechanisms of learning, emulation, and cooperative interdependence. Drawing on Chinese and Russian models—and facilitated by Western and Chinese tech companies—Turkey has adopted sophisticated digital control strategies across legal, surveillance, and information domains. The study identifies how strategic partnerships, infrastructure agreements (e.g., Huawei’s 5G and smart city projects), and shared authoritarian logics have enabled the Erdoğan regime to suppress dissent and reshape

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Reed, Anna, Hannah McKinley, Dante Jester, Brian G. Henning, and Tania Busch Isaksen. Building a Smoke-Resilient Spokane: Guidance from Community Conversations. Institute for Climate, Water, and the Environment (Gonzaga University, Spokane, WA), 2025. https://doi.org/10.33972/ccse.2025.01.

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Wildfire season has grown in length and severity in the western United States due to decades of fire suppression and climate change. This trend is projected to continue, worsening air quality and increasing the risk to public health. In response, the Gonzaga Institute for Climate, Water, and the Environment, in partnership with the University of Washington, hosted the Smoke Ready Spokane Symposium in July 2024 in Spokane, Washington. The event convened community partners across sectors to reflect on past wildfire smoke events and discuss locally-relevant wildfire smoke exposure reduction strat

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Abrigo, Michael, Jhanna Uy, Nel Jason Haw, Valerie Gilbert Ulep, and Kris Francisco-Abrigo. Projected Disease Transmission, Health System Requirements, and Macroeconomic Impacts of the Coronavirus Disease 2019 (COVID-19) in the Philippines. Philippine Institute for Development Studies, 2020. https://doi.org/10.62986/dp2020.15.

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The novel Coronavirus Disease 2019 (COVID-19) is a global pandemic that has infected at least 1.2 million people and caused more than 67,000 deaths worldwide. The Philippines has recorded 3,764 confirmed cases and 177 deaths as of April 7, 2020 and has implemented an enhanced Luzon-wide enhanced community quarantine (ECQ) from March 17 to April 30 in attempts to limit population movement and curb the spread of the epidemic. Based on the disease transmission model, it is projected that aggressive efforts in the post-ECQ period to isolate at least 70 percent of infectious cases through better co

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Manulis-Sasson, Shulamit, Christine D. Smart, Isaac Barash, Laura Chalupowicz, Guido Sessa, and Thomas J. Burr. Clavibacter michiganensis subsp. michiganensis-tomato interactions: expression and function of virulence factors, plant defense responses and pathogen movement. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7594405.bard.

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Clavibactermichiganensissubsp. michiganensis(Cmm), the causal agent of bacterial wilt and canker of tomato, is the most destructive bacterial disease of tomato causing substantial economic losses in Israel, the U.S.A. and worldwide. The goal of the project was to unravel the molecular strategies that allow Cmm, a Gram-positive bacterium, to develop a successful infection in tomato. The genome of Cmm contains numerous genes encoding for extracellular serine proteases and cell wall degrading enzymes. The first objective was to elucidate the role of secreted serine proteases in Cmm virulence. Mut

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Kelly, Luke. Direct and Indirect Impacts of the COVID-19 Pandemic on Women and Girls. Institute of Development Studies (IDS), 2021. http://dx.doi.org/10.19088/k4d.2021.141.

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This rapid literature review finds that women have been disproportionately affected by Covid-19 in several ways. As the Covid-19 pandemic began, it was widely predicted that women would face worse outcomes than men in many spheres. This was based on evidence of pre-existing inequalities (e.g. the high share of women in informal work) and evidence from earlier disease outbreaks such as Ebola. Evidence from the past year and a half supports the idea that women have been disproportionately affected by Covid-19 in many of the issues investigated for this report. A wide-ranging World Bank review of

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