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1

Danladi, Suleiman, Musa Aliyu Muhammad, and Abdullahi Hamza Yaro. "Central nervous system depressant activity of ethanol leaf extract of Globimetula braunii (Engler) (Loranthaceae) growing on Terminalia catappa L. (Combretaceae)." Bayero Journal of Pure and Applied Sciences 12, no. 1 (2020): 321–27. http://dx.doi.org/10.4314/bajopas.v12i1.49s.

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This study was carried out to determine phytochemical constituents, median lethal dose (LD50) and central nervous system depressant activity of ethanol leaf extract of Globimetula braunii using laboratory animal models. The intraperitoneal median lethal dose (LD50) of ethanol leaf extract of Globimetula braunii was determined in mice according to the method described by Lorke, 1983. The CNS depressant activity of Globimetula braunii leaf extract was determined using diazepam induced sleep, hole board test and beam walk assay. The ethanol leaf extract of Globimetula braunii revealed the presenc
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2

Danladi, Suleiman, and Aisha M. Alhassan. "Isolation of quercetin-3-<i>O</i>-rutinoside from the leaves of <i>Globimetula braunii</i> (Loranthaceae) growing on <i>Terminalia catappa</i> (Combretaceae)." Journal of Pharmacy & Bioresources 21, no. 1 (2024): 1–4. http://dx.doi.org/10.4314/jpb.v21i1.1.

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Globimetula braunii is a medicinal plant that grows in tropical countries and is used in the treatment of various diseases. The plant was reported to contain several secondary metabolites that are responsible for its therapeutic activities. This study aimed to isolate more flavonoid compounds present in the n-butanol fraction of the ethanol leaf extract of the plant. The n-butanol fraction of an ethanol leaf extract of Globimetula braunii was subjected to column chromatography over silica gel, and repeated gel filtration with Sephadex LH-20 eluted with methanol led to the isolation of a compou
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3

Raji, Basirat Atinuke, Idayat Adeola Akinwumi, and Mubo Adeola Sonibare. "Evaluation of antioxidant and antacid activities of <i>Globimetula braunii</i> and <i>Parquetina nigrescens</i> extracts." Nigerian Journal of Natural Products and Medicine 27, no. 1 (2024): 44–50. http://dx.doi.org/10.4314/njnpm.v27i1.7.

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Natural products are one of the best sources of therapeutic-based compounds for the treatment of peptic ulcer, which denotes open sores on the lining of the stomach or small intestines. Globimetula braunii (Family Loranthaceae), Microdesmis puberula (Family Pandaceae) and Parquetina nigrescens (Family Apocynaceae) have been documented for various medicinal uses, including the traditional treatment of peptic ulcer in Nigeria. This study aimed to assess the antioxidant and antacid properties of Globimetula braunii, Microdesmis puberula and Parquetina nigrescens. The plant samples were collected,
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4

Okpuzor, J., G. Kareem, and C. Ejikeme. "Lipid Lowering Activity of Globimetula braunii." Research Journal of Medicinal Plant 3, no. 2 (2009): 45–51. http://dx.doi.org/10.3923/rjmp.2009.45.51.

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5

Azangue, Gilles Jiope, Bonaventure Sonke, and Wauffo Fokom David. "Inventory of Loranthaceae parasites of Bayangam fruit trees in West Cameroon." JSFA reports 4, no. 6 (2024): 269–75. http://dx.doi.org/10.1002/jsf2.209.

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AbstractBackgroundLoranthaceae parasitism is a limiting factor for crops as well as many other plant diseases and pests. The present study was conducted to make an inventory of Loranthaceae present on fruit trees species grown in the Bayangam locality. It also aimed to record the damage caused by these pests on the host plants. To achieve this, 40 transects of 100 m length and 50 m width were set up in the locality of Bayangam. Observations were made on the presence or absence of the parasites on the host plants, the number of Loranthaceae clumps carried by each parasitized tree, the taxon of
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Ayoola, Marcus Durojaye, Ayodeji Oluwabunmi Oriola, Kolade Olatubosun Faloye, and Adetunji Joseph Aladesanmi. "Two antihyperglycaemic compounds from Globimetula braunii (Engl.) Van Tiegh (Loranthaceae)." GSC Biological and Pharmaceutical Sciences 11, no. 1 (2020): 046–54. https://doi.org/10.5281/zenodo.4276908.

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Large numbers of medicinal plants are constantly being screened for possible pharmacological values, especially for chronic diseases such as diabetes, with the view of discovering new compounds that may serve as templates for synthesis of more active/less toxic drugs. Therefore, the antihyperglycaemic activity of the leaf of&nbsp;<em>Globimetula braunii</em>&nbsp;with antidiabetic ethnomedical usage in Nigeria was investigated is this study to justify this folkloric claim. The median lethal dose, LD<sub>50</sub>&nbsp;of the ethanol leaf extract of&nbsp;<em>G. braunii&nbsp;</em>was determined u
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7

Alhassan, Aisha Muhammad, Nafisah Bisallah Lawal, and Suleiman Danladi. "Analgesic and anti-inflammatory studies of the methanol extract of Globimetula braunii (Loranthaceae) growing on Terminalia catappa Linn (Combretaceae)." Journal of Pharmacy & Bioresources 20, no. 2 (2023): 74–80. http://dx.doi.org/10.4314/jpb.v20i2.2.

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This study was carried out to investigate the phytochemical constituents, analgesic and anti-inflammatory activity of methanol stem extract of Globimetula braunii. Preliminary phytochemical screening was done using standard protocols, median lethal dose (LD50) was determined by Lorke’s method. Analgesic and anti-inflammatory activities of extract were determined using acetic acid induced writhing and hot-plate model and the carrageenan-induced rat's paw edema model respectively at graded doses of 1000 mg/kg, 500 mg/kg and 250mg/kg. The phytochemical screening revealed the presence of flavonoid
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8

Erukainure, Ochuko L., Joseph A. Abovwe, Adeniyi S. Adefegha, Rabiat U. Egwuche, and Michael A. Fafunso. "Antilipemic and hypocholesteremic activities of Globimetula braunii in rats." Experimental and Toxicologic Pathology 63, no. 7-8 (2011): 657–61. http://dx.doi.org/10.1016/j.etp.2010.05.007.

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9

Danladi, Suleiman, Mohammed Ibrahim Sule, Musa Aliyu Muhammad, and Abdullahi Hamza Yaro. "Central nervous system depressant activity of fractions of Globimetula braunii Engl. (Loranthaceae) growing on Terminalia catappa L. (Combretaceae) and isolation of lupeol." Journal of Pharmacy & Bioresources 18, no. 3 (2021): 196–206. http://dx.doi.org/10.4314/jpb.v18i3.4.

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Globimetula braunii is a parasitic plant belonging to the family Loranthaceae. Traditionally, the plant has been reported to be used in the treatment of insomnia. The study was carried out to investigate the central nervous system (CNS) depressant activity of the fractions of Globimetula braunii growing on Terminalia catappa and to isolate the phytochemical compound(s) present in the most active fraction. The CNS depressant activity of all the fractions was investigated using diazepam induced sleep. The most active fraction was further subjected to the hole board test and beam walk assay. The
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10

Okpanachi, Gideon O., Avosuahi R. Oyi, Hassan Musa, Abdulrahman Abdulsamad, Ifeanyi V. Emenike, and Yahaya Z. Sule. "Assessment of physicochemical properties of Globimetula braunii (Loranthaceae) leaf extracts." Journal of Science and Practice of Pharmacy 7, no. 1 (2020): 344–54. http://dx.doi.org/10.47227/jsppharm.v7i1.1.

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Purpose: This study is aimed at assessing the physicochemical properties of the leaves, ethanolic leaf extract (GBE), petroleum ether fraction (PEF) and n-butanol fraction (NBF) of Globimetula braunii leaves. Methods: Physicochemical tests such as moisture content, pH, total ash, acid insoluble ash, water/alcohol soluble extractives and heavy metal limit tests were conducted on the leaf powder. GBE was partitioned with petroleum ether, ethyl acetate and n-butanol to get PEF, EAF and NBF fractions respectively. GBE, PEF and NBF were assessed for solubility, maximum wave length of absorption, mo
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11

Ja'afar, Muhammad Kamal, Shajarahtunnur Jamil, Norazah Basar, et al. "Lactones and Flavonoids isolated from the Leaves of Globimetula braunii." Natural Product Communications 12, no. 9 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200918.

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The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAc-soluble and MeOH-soluble extracts successfully yielded two lactones namely ( R)-6-[( S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]–5,6-dihydropyran-2-one (dodoneine) 1 and (1 R,5 S,7 S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of com
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12

Ayoola Marcus Durojaye, Oriola Ayodeji Oluwabunmi, Faloye Kolade Olatubosun, and Aladesanmi Adetunji Joseph. "Two antihyperglycaemic compounds from Globimetula braunii (Engl.) Van Tiegh (Loranthaceae)." GSC Biological and Pharmaceutical Sciences 11, no. 1 (2020): 046–54. http://dx.doi.org/10.30574/gscbps.2020.11.1.0066.

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13

Oriola, Ayodeji Oluwabunmi, Adetunji Joseph Aladesanmi, Thomas Oyebode Idowu, et al. "Ursane-Type Triterpenes, Phenolics and Phenolic Derivatives from Globimetula braunii Leaf." Molecules 26, no. 21 (2021): 6528. http://dx.doi.org/10.3390/molecules26216528.

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Globimetula braunii is a hemi-parasitic plant used in African ethnomedicine for the management of microbial infections, rheumatic pain and tumors amongst others. We report the isolation and characterization of eight compounds with their antioxidant and antimicrobial activities. The air-dried powdered leaf was macerated in EtOH/H20 (4:1). The extract was solvent-partitioned into n-hexane, EtOAc, n-BuOH and aqueous fractions. The fractions were screened for their antioxidant properties, using DPPH, FRAP, TAC and FIC assays. Antimicrobial analysis was performed using the micro-broth dilution meth
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14

Okpanachi, Gideon, Avosuahi Oyi, Hassan Musa, A. Abdulsamad, Muhammad Sani, and Jamilu Ya’u. "Phytochemical Screening and Hypoglycemic Property of Globimetula braunii (Loranthaceae) Leaf Extracts." Journal of Pharmaceutical Research International 22, no. 1 (2018): 1–11. http://dx.doi.org/10.9734/jpri/2018/39870.

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15

Mana, Djibrilla, Souare Konsala, and Ibrahima Adamou. "Diversité et importance socio-économique des Loranthaceae parasites des plantes ligneuses des Monts Mandara dans la Région de l’Extrême-Nord, Cameroun." International Journal of Biological and Chemical Sciences 15, no. 2 (2021): 578–93. http://dx.doi.org/10.4314/ijbcs.v15i2.16.

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Les Loranthaceae constituent des ressources précieuses pour les populations locales africaines. Cependant, peu d’ethnies connaissent l’importance socio-économique des Loranthaceae de par le manque d’études ethnobotaniques sur ces espèces. Afin de contribuer à la valorisation et à la gestion durable des Loranthaceae parasites des plantes ligneuses, une approche associant deux méthodes a été adoptée. L’une, basée sur des relevés de surface et l’autre sur une enquête ethnobotanique relative aux connaissances locales des Loranthaceae dans 9 Arrondissements de la Région de l’Extrême-Nord du Camerou
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16

Weston, Kerry A., Hazel M. Chapman, Dave Kelly, and Elena V. Moltchanova. "Dependence on sunbird pollination for fruit set in three West African montane mistletoe species." Journal of Tropical Ecology 28, no. 2 (2012): 205–13. http://dx.doi.org/10.1017/s026646741100068x.

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Abstract:Theory predicts that not all plant species will be equally affected by disruption to their pollinator mutualisms because traits such as breeding system and mutualism strength can affect their response. We investigated these traits in three species of Afromontane mistletoe Globimetula braunii, Agelanthus brunneus and A. djurensis in Ngel Nyaki Forest Reserve, Nigeria, to test whether the traits were reliable indicators of relative reproductive success and could be used to predict relative vulnerability to pollinator loss. For each mistletoe species, insect and bird visitors were identi
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17

Okpuzor, J., H. Ogbunugafo, and G. K. Kareem. "Antioxidative Properties of Ethyl Acetate Fraction of Globimetula braunii in Normal Albino Rats." Journal of Biological Sciences 9, no. 5 (2009): 470–75. http://dx.doi.org/10.3923/jbs.2009.470.475.

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18

Muhammad, Kamal Ja’afar, Shajarahtunnur Jamil, Norazah Basar, Satyajit D. Sarker, and Magaji Garba Mohammed. "Globrauneine A–F: six new triterpenoid esters from the leaves of Globimetula braunii." Natural Product Research 34, no. 19 (2019): 2746–53. http://dx.doi.org/10.1080/14786419.2019.1586693.

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19

Olanlokun, John Oludele, Mercy Toluwase Ekundayo, Neil Anthony Koorbanally, and Olufunso Olabode Olorunsogo. "Hexane fraction of Globimetula braunii induces mitochondria-mediated apoptosis in Plasmodium berghei-infected mice." Toxicology Reports 9 (2022): 769–77. http://dx.doi.org/10.1016/j.toxrep.2022.04.002.

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20

Mana, Djibrilla, Haiwa Gilbert, Kengne Olivier Clovis, Souare Konsala, and Ibrahima Adamou. "ASSESSMENT OF INFESTATION AND DISTRIBUTION OF LORANTHACEAE ON WOODY PLANTS OF THE MANDARA MOUNTAINS OF THE FAR NORTH REGION, CAMEROON." International Journal of Advanced Research 12, no. 04 (2024): 1128–41. http://dx.doi.org/10.21474/ijar01/18653.

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Loranthaceae are a permanent danger to many woody plant species. The present study was carried out with the aim of evaluating the degree of parasitism of Loranthaceae on woody species of the Mandara Mountains in the Far North Region of Cameroon. A methodological approach based on surface surveys was adopted. On the hills, the species of Loranthaceae encountered and the host plants have been identified. The botanical inventory revealed a floristic composition of 73 species of phorophytes distributed in 43 genera and 24 families. These phorophytes are parasitized by 7 species of Loranthaceae (Ag
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21

Miaffo, David, Kilenma Kolefer, Elizé Dadaya, Barthelemy Maidadi, Abba Talba Mahamad, and Albert Kamanyi. "Globimetula braunii prevents hyperglycemia, oxidative damage, and hepatorenal dysfunction in dexamethasone-induced insulin-resistant rats." Journal of Herbmed Pharmacology 14, no. 1 (2024): 43–52. https://doi.org/10.34172/jhp.2025.52546.

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Introduction: Globimetula braunii is a parasitic plant used in Cameroon in traditional medicine to treat diabetes mellitus. The present work aimed to evaluate the protective effects of aqueous leaf extract of G. braunii (EGB) on rats rendered insulin-resistant by dexamethasone. Methods: To induce insulin resistance, male rats received a subcutaneous dexamethasone injection (1 mg/kg) daily for 10 days. One hour before the administration of dexamethasone, the animals received vehicle, metformin (40 mg/kg), or EGB (120, 240, and 480 mg/kg). Body weight, glycemia, insulinemia, homeostatic model as
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Aliyu, Musa Mumammad, Abdullahi Isma'il Musa, Muhammad Ja'afar Kamal, and Magaji Garba Mohammed. "Phytochemical screening and anticonvulsant studies of ethyl acetate fraction of Globimetula braunii on laboratory animals." Asian Pacific Journal of Tropical Biomedicine 4, no. 4 (2014): 285–89. http://dx.doi.org/10.12980/apjtb.4.2014c925.

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23

Amon Anoh Denis-Esdras, Ahoulou Assoum Stanislas, Achah Jacques Auguste Alfred Bognan, et al. "Ethnobotanical knowledge of medicinal values of Loranthaceae used to treat human diseases by local ethnic Agni Sanwi from Aboisso and Maferé in Côte d'Ivoire." World Journal of Biology Pharmacy and Health Sciences 4, no. 1 (2020): 039–50. http://dx.doi.org/10.30574/wjbphs.2020.4.1.0083.

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Loranthaceae are hemiparasitic vascular plants that develop on other woody species. They are used in traditional medicine to treat various pathologies. The present study is a contribution to the knowledge of the medicinal potential of Loranthaceae used in care by Agni Sanwi of Aboisso and Maferé, in the South-East of Côte d'Ivoire. Ethnobotanical surveys were conducted with 50 herbalists and 17 traditional healers using semi-structured interviews. Three (3) species (Globimetula braunii, Phragmanthera capitata and Tapinanthus bangwensis) divided into 3 genera used to treat 35 diseases were iden
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Olanlokun, John Oludele, Mercy Toluwase Ekundayo, Oluwakemi Ebenezer, Neil Anthony Koorbanally, and Olufunso Olabode Olorunsogo. "Antimalarial and Erythrocyte Membrane Stability Properties of Globimetula braunii (Engle Van Tiegh) Growing on Cocoa in Plasmodium berghei-Infected Mice." Infection and Drug Resistance Volume 14 (September 2021): 3795–808. http://dx.doi.org/10.2147/idr.s317732.

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25

Amon, Anoh Denis-Esdras, Assoum Stanislas Ahoulou, Jacques Auguste Alfred Bognan Achah, et al. "Ethnobotanical knowledge of medicinal values of Loranthaceae used to treat human diseases by local ethnic Agni Sanwi from Aboisso and Maferé in Côte d'Ivoire." World Journal of Biology Pharmacy and Health Sciences 4, no. 1 (2020): 039–50. https://doi.org/10.5281/zenodo.4430583.

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Loranthaceae are hemiparasitic vascular plants that develop on other woody species. They are used in traditional medicine to treat various pathologies. The present study is a contribution to the knowledge of the medicinal potential of Loranthaceae used in care by Agni Sanwi of Aboisso and Mafer&eacute;, in the South-East of C&ocirc;te d&#39;Ivoire. Ethnobotanical surveys were conducted with 50 herbalists and 17 traditional healers using semi-structured interviews. Three (3) species (<em>Globimetula braunii</em>,&nbsp;<em>Phragmanthera capitata&nbsp;</em>and&nbsp;<em>Tapinanthus bangwensis</em>
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26

Ja’afar, Muhammad Kamal, Shajarahtunnur Jamil, and Norazah Basar. "ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF GLOBIMETULA BRAUNII (ENGLER) VAN TIEGH PARASITIZING ON PILIOSTIGMA THONNINGII AND PARKIA BIGLOBOSA." Jurnal Teknologi 79, no. 5 (2017). http://dx.doi.org/10.11113/jt.v79.10574.

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The dried leaves of Globimetula braunii parasitizing on Piliostigma thonningii and Parkia biglobosa were successively extracted using n-hexane, dichloromethane, ethyl acetate and methanol by cold extraction method. All the extracts were evaluated for antioxidant activities using FRAP, ABTS and DPPH assays. The MeOH extract of G. braunii parasitizing on P. thonningii displayed the highest DPPH scavenging activity with SC50 value 2.82 µg/mL while the EtOAc extract of G. braunii parasitizing on P. biglobosa showed highest antioxidant scavenging capacity in the ABTS assay with SC50 value of 138.9
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27

Evariste Leonce, Azabadji Ashu, Priyanka Devi, Tagne Simo Richard, et al. "Anti-melanoma and antioxidant properties of the methanol extract from the leaves of Phragmenthera capitata (Spreng.) Balle and Globimetula braunii (Engl.) Van Tiegh." Journal of Complementary and Integrative Medicine, November 3, 2023. http://dx.doi.org/10.1515/jcim-2023-0225.

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Abstract Objectives Phragmenthera capitata (Spreng.) Balle and Globimetula braunii (Engler.) Van Tiegh are African mistletoe traditionally used in cancers treatment. Thus, the aim of the study was to assess the anti-melanoma potential of the methanol extract of Phragmenthera capitata (Spreng.) Balle (PCMe-OH) and Globimetula braunii (Engler.) (GBMe-OH) Van Tiegh. Methods Antioxidant potential was evaluated using DPPH, FRAP and hydroxyl assays. Total flavonoid and phenolic contents was also determined. MTT assay was used to estimate the effects on cell viability using SK-MLE28 and B16-F10 cell
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28

"Phytochemical Constituents and Pharmacological Activities of Globimetula braunii (Loranthaceae): A Review." Tropical Journal of Natural Product Research 6, no. 9 (2022): 1372–77. http://dx.doi.org/10.26538/tjnpr/v6i9.4.

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29

Oriola, Ayodeji O., Pallab Kar, and Adebola O. Oyedeji. "Sourcing antimicrobial agents from Globimetula braunii: An in silico molecular docking and dynamic approach." Journal of Phytology, September 9, 2024, 163–68. http://dx.doi.org/10.25081/jp.2024.v16.8850.

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The continued emergence of multi-drug resistance pathogens has been a major setback to lifting the burden of infectious diseases, especially bacterial illnesses. Natural- and/or nature-inspired compounds have so far become a therapeutic backbone on which many novel antibacterial agents are optimized. It is against this backdrop that we used an in silico molecular interaction-based approach to screen five previously identified compounds from Globimetula braunii, for lead inhibitors against bacterial illnesses. The compounds were chromatographed from the leaf ethyl acetate fraction and were char
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30

Oriola, A. O., A. J. Aladesanmi, E. O. Akinkunmi, and I. J. Olawuni. "Antioxidant and Antimicrobial Studies of Some Hemi-parasitic West African Plants." European Journal of Medicinal Plants, February 27, 2020, 17–26. http://dx.doi.org/10.9734/ejmp/2020/v31i330219.

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The study investigated the antioxidant and antimicrobial activities of some West African hemi-parasitic plants, which comprised Tapinanthus bangwensis (TB), Tapinanthus globiferus (TG) and Globimetula braunii (GB), used in Nigerian ethnomedicine for the management of skin and other microbial infections. This was with a view to determining the most active plant extract and fraction. The leaf and stem of each plant was separately air-dried, powdered and macerated in ethanol-H20 (8:2). The extracts were subjected to in vitro antioxidant tests such as 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric r
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31

Ja’afar Muhammad, Kamal, Shajarahtunnur Jamil, Norazah Basar, and Mohammed Garba Magaji. "ANTICONVULSANT EFFECT OF ISOLATED COMPOUNDS FROM THE LEAVES OF GLOBIMETULA BRAUNII ENGLER VAN TIEGH (LORANTHACEAE) IN MICE AND CHICKS." Jurnal Teknologi (Sciences & Engineering) 87, no. 1 (2024). http://dx.doi.org/10.11113/jurnalteknologi.v87.21562.

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The anticonvulsant evaluation of globrauneine A (1), globrauneine C (2) globrauneine D (3), globrauneine F (4), lupeol (5), β-sitosterol (6), (1R,5S,7S)-7-[2-(4-hydroxyphenyl) ethyl]-2,6-dioxabi-cyclo [3. 3.1]-nonan-3-one (7), dodoneine (8), quercetin (9) and rutin (10) from Globimetula braunii leaves were analyzed with the aid of pentylenetetrazole-induced seizure test in mice (PTZ) and maximal electroshock seizure test in chicks (MEST), while the neurotoxicity was evaluated using the beam walking assay in mice. 50% of the tested mice were protected by Globrauneine A (1) and dodoneine (8) aga
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