Relevant bibliographies by topics / GLRA2

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  2. Dissertations / Theses
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  4. Book chapters
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Academic literature on the topic 'GLRA2'

Author: Grafiati
Published: 25 May 2024
Last updated: 19 July 2025

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Journal articles on the topic "GLRA2"

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Kumar, Priyadarsini, and Stanley Meizel. "Identification and spatial distribution of glycine receptor subunits in human sperm." REPRODUCTION 136, no. 4 (2008): 387–90. http://dx.doi.org/10.1530/rep-08-0223.

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The human sperm surface glycine receptor (GLR) plays a role in an important fertilization event, the sperm acrosome reaction. Here, by western blot analysis, we report the presence of GLRA1, GLRA2, GLRA3, and GLRB subunits in human sperm. Immunolocalization studies showed that the GLRA1 and GLRA2 subunits are present in the equatorial region, the GLRA3 subunit in the flagellar principal piece, and the GLRB subunit in the acrosomal region of sperm. This first demonstration of isoforms of the sperm GLRA subunit and of a differential spatial distribution of the α and β subunits on the surface of
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Tuệ, Nguyễn Trọng, та Ngô Thị Huyền Linh. "Vai trò của GLRA2 trong mối liên quan đến hội chứng rối loạn phổ tự kỷ trên mô hình ruồi giấm". Tạp chí Nghiên cứu Y học 189, № 4 (2025): 100–109. https://doi.org/10.52852/tcncyh.v189i4.3350.

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Hội chứng rối loạn phổ tự kỷ (ASD - Autism Spectrum Disoder) là một tình trạng rối loạn hành vi nghiêm trọng. Bệnh đặc trưng bởi các rối loạn thần kinh bao gồm việc khó khăn trong giao tiếp, tương tác xã hội, phát triển ngôn ngữ, hành vi lặp đi lặp lại. Một số bằng chứng gần đây cho thấy gen GLRA2 có mối liên quan tới hội chứng ASD. Trong nghiên cứu này, chúng tôi sử dụng hệ thống GAL4/UAS làm giảm biểu hiện gen GLRA2 trên mô não và đánh giá mức độ ảnh hưởng của protein này lên khả năng tương tác xã hội, vận động và nhịp thức ngủ của ruồi giấm. Kết quả cho thấy khả năng vận động của ruồi giảm
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Nachman, Michael W. "Patterns of DNA Variability at X-Linked Loci in Mus domesticus." Genetics 147, no. 3 (1997): 1303–16. http://dx.doi.org/10.1093/genetics/147.3.1303.

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Introns of four X-linked genes (Hprt, Plp, Glra2, and Amg) were sequenced to provide an estimate of nucleotide diversity at nuclear genes within the house mouse and to test the neutral prediction that the ratio of intraspecific polymorphism to interspecific divergence is the same for different loci. Hprt and Plp lie in a region of the X chromosome that experiences relatively low recombination rates, while Glra2 and Amg lie near the telomere of the X chromosome, a region that experiences higher recombination rates. A total of 6022 bases were sequenced in each of 10 Mus domesticus and one M. car
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Young-Pearse, T. L., L. Ivic, A. R. Kriegstein, and C. L. Cepko. "Characterization of Mice with Targeted Deletion of Glycine Receptor Alpha 2." Molecular and Cellular Biology 26, no. 15 (2006): 5728–34. http://dx.doi.org/10.1128/mcb.00237-06.

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ABSTRACT Glycine receptors are ligand-gated chloride channels that mediate inhibitory neurotransmission in the adult nervous system. During development, glycine receptor alpha 2 (GlyRα2) is expressed in the retina, in the spinal cord, and throughout the brain. Within the cortex, GlyRα2 is expressed in immature cells and these receptors have been shown to be active and excitatory. In the developing retina, inhibition of glycine receptor activity prevents proper rod photoreceptor development. These data suggest that GlyRα2, the developmentally expressed glycine receptor, may play an important ro
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MAJUMDAR, SRIPARNA, LIANE HEINZE, SILKE HAVERKAMP, ELENA IVANOVA, and HEINZ WÄSSLE. "Glycine receptors of A-type ganglion cells of the mouse retina." Visual Neuroscience 24, no. 4 (2007): 471–87. http://dx.doi.org/10.1017/s0952523807070174.

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A-type ganglion cells of the mouse retina represent the visual channel that transfers temporal changes of the outside world very fast and with high fidelity. In this study we combined anatomical and physiological methods in order to study the glycinergic, inhibitory input of A-type ganglion cells. Immunocytochemical studies were performed in a transgenic mouse line whose ganglion cells express green fluorescent protein (GFP). The cells were double labeled for GFP and the four α subunits of the glycine receptor (GlyR). It was found that most of the glycinergic input of A-type cells is through f
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Schaefermeier, Philipp, and Sarah Heinze. "Hippocampal Characteristics and Invariant Sequence Elements Distribution of GLRA2 and GLRA3 C-to-U Editing." Molecular Syndromology 8, no. 2 (2016): 85–92. http://dx.doi.org/10.1159/000453300.

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Li, Xiaoxia, Siyu Wang, Yuhan Wang, et al. "Clinical and Molecular Landscape of GLRA2 in X-Linked Early-Onset High Myopia." Investigative Ophthalmology & Visual Science 66, no. 4 (2025): 30. https://doi.org/10.1167/iovs.66.4.30.

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McCracken, Lindsay M., Daniel C. Lowes, Michael C. Salling та ін. "Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain". Proceedings of the National Academy of Sciences 114, № 34 (2017): E7179—E7186. http://dx.doi.org/10.1073/pnas.1703839114.

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Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic inhibition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of α1 and β subunits. Inhibitory GlyRs are also found throughout the brain, where GlyR α2 and α3 subunit expression exceeds that of α1, particularly in forebrain structures, and coassembly of these α subunits with the β subunit appears to occur to a lesser extent than in spinal cord. Here, we analyzed GlyR currents in several regions of the adolescent
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Alitalo, Tiina, Fiona Francis, Juha Kere, Hans Lehrach, David Schlessinger, and Huntington F. Willard. "A 6-Mb YAC contig in Xp22.1–p22.2 spanning the DXS69E, XE59, GLRA2, PIGA, GRPR, CALB3, and PHKA2 genes." Genomics 25, no. 3 (1995): 691–700. http://dx.doi.org/10.1016/0888-7543(95)80012-b.

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Feng, Jinong, Nick Craddock, Ian R. Jones та ін. "Systematic screening for mutations in the glycine receptor α2 subunit gene (GLRA2) in patients with schizophrenia and other psychiatric diseases". Psychiatric Genetics 11, № 1 (2001): 45–48. http://dx.doi.org/10.1097/00041444-200103000-00009.

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Dissertations / Theses on the topic "GLRA2"

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Upton, Laura. "Altered prefrontal circuit assembly and function in mice lacking the glycine receptor α2 subunit, a model of autism and intellectual disability". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS714.

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Des variants pathogènes du gène GLRA2 codant pour la sous-unité α2 du récepteur glycinergique ont été récemment impliqués dans le trouble du spectre autistique (TSA) et la déficience intellectuelle. Notre groupe a précédemment montré que les souris mâles déficientes en Glra2 (Glra2–/Y) présentent un déficit de mémoire lors du test de reconnaissance d’objets (TRO) et une altération de la plasticité synaptique du cortex préfrontal (CPF), une région fortement impliquée dans le TSA. Par ailleurs, des études développementales des souris Glra2–/Y ont décrit un défaut de migration des interneurones e
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Martins, Ana Caroline Vasconcelos. "GluA2 - Glutamatergic Receptor Study: A Molecular Approach." reponame:Repositório Institucional da UFC, 2017. http://www.repositorio.ufc.br/handle/riufc/28258.

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Submitted by José Orlando Soares de Oliveira (orlando.soares@bol.com.br) on 2017-11-30T12:23:47Z No. of bitstreams: 1 2017_tese_acvmartins.pdf: 10270409 bytes, checksum: f2b0eb40db54875e0e40a6d040ce7336 (MD5)<br>Rejected by Weslayne Nunes de Sales (weslaynesales@ufc.br), reason: A aluna optou por publicar apenas os elementos pré-textuais. on 2017-12-01T12:36:51Z (GMT)<br>Submitted by José Orlando Soares de Oliveira (orlando.soares@bol.com.br) on 2017-12-01T13:50:35Z No. of bitstreams: 1 Tese corrigida - elementos pretextuais.pdf: 159585 bytes, checksum: 9531b29bc8c5a46f5ed5753442df383f (M
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Jones, Taylor J. "Documentation of grapevine leafroll-associated viruses in wine grape varieties and native grape species in Virginia, and examination of the movement of grapevine leafroll disease to develop management strategies." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/49567.

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Grapevine leafroll-associated virus-2 (GLRaV-2), GLRaV-3, and grapevine fleck virus (GFkV) are widespread in grapes around the world. These viruses can cause significant crop loss and affect wine quality by reducing sugar accumulation and compromising skin color. Mealybugs are vectors of grapevine leafroll-associated viruses (GLRaVs). A statewide survey of commercial and wild grapevines in Virginia was conducted during 2009 through 2011. Also, vector management options were tested in two field studies. GLRaV-2, GLRaV-3, and GFkV were detected in 8%, 25%, and 1%, respectively, of over 1,200 vin
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Fazeli, Claudia Fariba. "Molecular detection of grapevine leafroll associated closteroviruses (GLRaVs) and the genome organisation of GLRaV-1." 1998, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phf2868.pdf.

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Little, Alan. "Complete sequence, improved detection and functional analysis of Grapevine Leafroll-associated Virus 1(GLRaV-1) /." Title page, table of contents and summary only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phl7781.pdf.

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Dubes, Sandra. "Rôle du microARN miR-124 dans la plasticité homéostatique via le contrôle de l’expression de la synaptopodine et des récepteurs AMPA dans les neurones de l'hippocampe." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0104.

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Le synaptic scaling est une forme de plasticité homéostatique par lequel les synapses ajustent leur efficacité pour compenser des variations normales ou pathologiques de l'activité neuronale notamment lors des maladies neurodégeneratives ou suite à la perte d’afférences sensorielles après une lésion. Dans un modèle expérimental classique, le traitement chronique des neurones primaires avec la tétrodotoxine (TTX) pour bloquer la propagation des potentiels d'action présynaptiques induit une augmentation significative de l'amplitude des courants miniatures excitateurs transmis par les récepteurs
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Alliaume, Antoine. "Biologie de la vection de l'ampélovirus GLRaV-1 et du vitivirus GVA par la cochenille Phenacoccus aceris." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAJ004.

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L’enroulement de la vigne cause des pertes de rendement et de la qualité des vins au niveau mondial. Il est causé par quatre espèces de Grapevine leafroll-associated virus(GLRaVs) ; GLRaV-1, -2, -3, -4-like. Si le GLRaV-2 (genre Closterovirus) ne possède pas de vecteur connu, les trois autres espèces (genre Ampelovirus) sont transmises par cochenilles(Coccoidea) qui contribuent à leur dispersion dans et entre les vignobles. Les vignobles de la France septentrionale (Alsace, Bourgogne, Champagne) sont les plus impactés par l’enroulement viral. Ce travail a porté sur le rôle vecteur de Phenacocc
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Chen, Ting-Jiun [Verfasser], and Maria [Akademischer Betreuer] Kukley. "In vivo regulation of oligodendrocyte precursor cell proliferation and differentiation by AMPA-receptor subunit GluA2 / Ting-Jiun Chen ; Betreuer: Maria Kukley." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1208690213/34.

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Carreno, Velazquez Thalia Lizbeth. "Structure-based drug discovery approaches to identify modulators of the Nrf2 pathway and glutamate receptors AMPA GluA2 and Kainate GluK1 and GluK2." Thesis, University of Sussex, 2018. http://sro.sussex.ac.uk/id/eprint/75046/.

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Nrf2 project: The protein nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that provides protection against oxidative stress and the dysfunction of this pathway has been suggested to be implicated in many neurodegenerative diseases. The aim of this thesis was to identify novel Nrf2 activators that disrupt the protein-protein interaction between Nrf2 and Keap1 and thereby induce increased expression of antioxidant enzymes and protective genes. The crystal structure of the Keap1-Nrf2 interface was used to perform a virtual screen and compounds from the screen were ass
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Le, Maguet Jean. "Epidémiologie de l'enroulement viral de la vigne dans les vignobles français septentrionaux et transmission par cochenilles vectrices." Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00768382.

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Les virus de l'enroulement de la vigne (Grapevine leafroll-associated virus, GLRaV) sont répandus mondialement et transmis à la vigne uniquement par cochenilles (Coccoidea). En France, l'enroulement viral affecte particulièrement les vignobles des régions septentrionales.L'approche biologique de la vection a montré la capacité de Phenacoccus aceris à transmettre à la vigne les GLRaV-1, -3, -4, -5, -6, -9 et ceux du bois strié Grapevine virus A et B. Cette étude est la première démonstration de la transmission du GLRaV-6 et confirme l'absence de spécificité des cochenilles dans la transmission
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Books on the topic "GLRA2"

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Ren, Ke, and Ronald Dubner. The first crystal structure of an ionotropic glutamate receptor ligand-binding core. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0032.

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The known functional ionotropic glutamate receptors (iGluRs) are composed of three major subtypes: AMPA, NMDA, and kainate. In 1998, in the landmark paper discussed in this chapter, Armstrong et al. provided the first crystal structure of an iGluR-subunit ligand-binding core, the S1S2 region of the rat GluA2 ‘flop’ isoform. They solved its structure with X-ray crystallography from selenomethonine crystals. They also identified residues involved in kainate binding, analysed allosteric sites that regulate affinity and specificity of the agonist, and mapped potential subunit–subunit interaction s
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Book chapters on the topic "GLRA2"

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Jia, Zhengping, and Graham Collingridge. "Regulation of Hippocampal mGluR-Dependent Long-Term Depression by GluA2-Dependent Cofilin-Mediated Actin Remodeling." In mGLU Receptors. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56170-7_12.

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Zhan, L., Z. Nie, J. Ye, et al. "Multiple Stages Classification of Alzheimer’s Disease Based on Structural Brain Networks Using Generalized Low Rank Approximations (GLRAM)." In Computational Diffusion MRI. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-11182-7_4.

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Conference papers on the topic "GLRA2"

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Marković, Zvjezdana, Iva Šikuten, Anita Bošnjak Mihovilović та ін. "THE INFLUENCE OF SANITARY STATUS AND THE POSITION OF EXPLANTS ON THE GROWTH AND DEVELOPMENT OF IN VITRO OF ꞌPLAVAC MALIꞌ AND ꞌPOŠIPꞌ". У 2nd International Symposium on Biotechnology. Faculty of Agronomy in Čačak, University of Kragujevac, 2024. http://dx.doi.org/10.46793/sbt29.21zm.

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This study determines the in vitro influence of viruses (GLRaV-1, GLRaV-3, GFLV, GVA) and the position of meristems on initial shoots on the growth and development of ‘Plavac Mali’ and ‘Pošip’ grapevine cultivars. Infected clones were inoculated on MS medium with 0.5 mg l1-1 benzylaminopurine (BAP) and 0.05 mg l-1 indole-3-acetic-acid (IAA). The positions of meristems were: a – 1st; b – 2nd and 3rd; and c – 4th and 5th. The height and number of nodes, as well as the size of callus, were measured four and eight weeks after inoculation. Clone, position of explants, and sanitary status show no si
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Zhu, Jinle, and Qiang Li. "GLRAM Algorithm Based Hybrid Precoding for mmWave Multiuser MIMO Systems." In 2018 IEEE 10th Sensor Array and Multichannel Signal Processing Workshop (SAM). IEEE, 2018. http://dx.doi.org/10.1109/sam.2018.8448511.

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Sheehan, Bernard N., and Yousef Saad. "Higher Order Orthogonal Iteration of Tensors (HOOI) and its Relation to PCA and GLRAM." In Proceedings of the 2007 SIAM International Conference on Data Mining. Society for Industrial and Applied Mathematics, 2007. http://dx.doi.org/10.1137/1.9781611972771.32.

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Lee, Leeko. "Detection of unique electromagnetic signatures from GLRaV-3 infected grapevine leaves at different stages of virus development." In 4ᵗʰ International Conference on AI ML, Data Science and Robotics. United Research Forum, 2024. https://doi.org/10.51219/urforum.2024.leeko-lee.

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Reports on the topic "GLRA2"

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Mawassi, Munir, and Valerian Dolja. Role of RNA Silencing Suppression in the Pathogenicity and Host Specificity of the Grapevine Virus A. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592114.bard.

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RNA silencing is a defense mechanism that functions against virus infection and involves sequence-specific degradation of viral RNA. Diverse RNA and DNA viruses of plants encode RNA silencing suppressors (RSSs), which, in addition to their role in viral counterdefense, were implicated in the efficient accumulation of viral RNAs, virus transport, pathogenesis, and determination of the virus host range. Despite rapidly growing understanding of the mechanisms of RNA silencing suppression, systematic analysis of the roles played by diverse RSSs in virus biology and pathology is yet to be completed
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Mawassi, Munir, and Valerian V. Dolja. Role of the viral AlkB homologs in RNA repair. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594396.bard.

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AlkB proteins that repair DNA via reversing methylation damage are conserved in a broad range of prokaryotes and eukaryotes including plants. Surprisingly, AlkB-domains were discovered in the genomes of numerous plant positive-strand RNA viruses, majority of which belong to the family Flexiviridae. The major goal of this research was to reveal the AlkB functions in the viral infection cycle using a range of complementary genetic and biochemical approaches. Our hypotheses was that AlkB is required for efficient replication and genetic stability of viral RNA genomes The major objectives of the r
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