Academic literature on the topic 'GlucoCEST'

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Journal articles on the topic "GlucoCEST"

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Jin, Tao, Hunter Mehrens, Kristy S. Hendrich, and Seong-Gi Kim. "Mapping Brain Glucose Uptake with Chemical Exchange-Sensitive Spin-Lock Magnetic Resonance Imaging." Journal of Cerebral Blood Flow & Metabolism 34, no. 8 (2014): 1402–10. http://dx.doi.org/10.1038/jcbfm.2014.97.

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Uptake of administered D-glucose (Glc) or 2-deoxy-D-glucose (2DG) has been indirectly mapped through the chemical exchange (CE) between glucose hydroxyl and water protons using CE-dependent saturation transfer (glucoCEST) magnetic resonance imaging (MRI). We propose an alternative technique—on-resonance CE-sensitive spin-lock (CESL) MRI—to enhance responses to glucose changes. Phantom data and simulations suggest higher sensitivity for this ‘glucoCESL’ technique (versus glucoCEST) in the intermediate CE regime relevant to glucose. Simulations of CESL signals also show insensitivity to B0-fluct
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Bender, Benjamin, Kai Herz, Anagha Deshmane, et al. "GLINT: GlucoCEST in neoplastic tumors at 3 T—clinical results of GlucoCEST in gliomas." Magnetic Resonance Materials in Physics, Biology and Medicine 35, no. 1 (2021): 77–85. http://dx.doi.org/10.1007/s10334-021-00982-5.

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Abstract Objective Clinical relevance of dynamic glucose enhanced (DGE) chemical exchange saturation transfer (CEST) imaging has mostly been demonstrated at ultra-high field (UHF) due to low effect size. Results of a cohort study at clinical field strength are shown herein. Materials and methods Motion and field inhomogeneity corrected T1ρ‐based DGE (DGE⍴) images were acquired before, during and after a d-glucose injection with 6.3 s temporal resolution to detect accumulation in the brain. Six glioma patients with clear blood–brain barrier (BBB) leakage, two glioma patients with suspected BBB
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Kim, Mina, Afroditi Eleftheriou, Luca Ravotto, et al. "What do we know about dynamic glucose-enhanced (DGE) MRI and how close is it to the clinics? Horizon 2020 GLINT consortium report." Magnetic Resonance Materials in Physics, Biology and Medicine 35, no. 1 (2022): 87–104. http://dx.doi.org/10.1007/s10334-021-00994-1.

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AbstractCancer is one of the most devastating diseases that the world is currently facing, accounting for 10 million deaths in 2020 (WHO). In the last two decades, advanced medical imaging has played an ever more important role in the early detection of the disease, as it increases the chances of survival and the potential for full recovery. To date, dynamic glucose-enhanced (DGE) MRI using glucose-based chemical exchange saturation transfer (glucoCEST) has demonstrated the sensitivity to detect both d-glucose and glucose analogs, such as 3-oxy-methyl-d-glucose (3OMG) uptake in tumors. As one
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Kim, Mina, Francisco Torrealdea, Sola Adeleke, et al. "Challenges in glucoCEST MR body imaging at 3 Tesla." Quantitative Imaging in Medicine and Surgery 9, no. 10 (2019): 1628–40. http://dx.doi.org/10.21037/qims.2019.10.05.

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Nasrallah, Fatima A., Guilhem Pagès, Philip W. Kuchel, Xavier Golay, and Kai-Hsiang Chuang. "Imaging Brain Deoxyglucose Uptake and Metabolism by Glucocest MRI." Journal of Cerebral Blood Flow & Metabolism 33, no. 8 (2013): 1270–78. http://dx.doi.org/10.1038/jcbfm.2013.79.

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2-Deoxy-D-glucose (2DG) is a known surrogate molecule that is useful for inferring glucose uptake and metabolism. Although 13C-labeled 2DG can be detected by nuclear magnetic resonance (NMR), its low sensitivity for detection prohibits imaging to be performed. Using chemical exchange saturation transfer (CEST) as a signal-amplification mechanism, 2DG and the phosphorylated 2DG-6-phosphate (2DG6P) can be indirectly detected in 1H magnetic resonance imaging (MRI). We showed that the CEST signal changed with 2DG concentration, and was reduced by suppressing cerebral metabolism with increased gene
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Kentrup, Dominik, Annika Busch, Helga Pawelski, Eberhard Schlatter, Verena Hoerr, and Stefan Reuter. "SP772NON-INVASIVE DETECTION OF ACUTE RENAL ALLOGRAFT REJECTION THROUGH GLUCOCEST MRI." Nephrology Dialysis Transplantation 30, suppl_3 (2015): iii632. http://dx.doi.org/10.1093/ndt/gfv201.05.

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Colgan, Niall, Matthew Donoghue, Zdzislaw Zuchora, Brendan Tuohy, and Wil van der Putten. "Investigation of GlucoCEST as novel clinical MR biomarker of glucose metabolism." Physica Medica 32, no. 7 (2016): 959. http://dx.doi.org/10.1016/j.ejmp.2016.05.048.

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Xu, Xiang, Jiadi Xu, Kannie W. Y. Chan, et al. "GlucoCEST imaging with on-resonance variable delay multiple pulse (onVDMP) MRI." Magnetic Resonance in Medicine 81, no. 1 (2018): 47–56. http://dx.doi.org/10.1002/mrm.27364.

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Kentrup, Dominik, Philipp Bovenkamp, Annika Busch, et al. "GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection." Kidney International 92, no. 3 (2017): 757–64. http://dx.doi.org/10.1016/j.kint.2017.04.015.

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Xu, Xiang, Jiadi Xu, Linda Knutsson, et al. "The effect of the mTOR inhibitor rapamycin on glucoCEST signal in a preclinical model of glioblastoma." Magnetic Resonance in Medicine 81, no. 6 (2019): 3798–807. http://dx.doi.org/10.1002/mrm.27683.

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Dissertations / Theses on the topic "GlucoCEST"

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Delebarre, Thaddée. "Development of fast and robust metabolic imaging in humans at high magnetic field." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPAST001.

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L'imagerie par résonance magnétique du transfert de saturation par échange chimique (IRM CEST) représente un outil puissant pour l'étude du métabolisme, offrant une résolution temporelle et spatiale supérieure ainsi qu'une sensibilité accrue par rapport à la spectroscopie par résonance magnétique. L'IRM CEST permet la détection indirecte de certains métabolites grâce à l'interaction entre leurs protons et ceux de l'eau. Le CEST peut cartographier le glucose, le glutamate et la créatine, qui sont des métabolites importants impliqués dans les cancers et les maladies neurodégénératives et musculo
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Books on the topic "GlucoCEST"

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Hogg and European Society Of Pneumology. Glucocort Inflam Bronch Hyper: (Current Clinical Practice). Elsevier Science & Technology, 1985.

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Book chapters on the topic "GlucoCEST"

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Torrealdea, Francisco, Marilena Rega, and Xavier Golay. "Chapter 17 GlucoCEST: Imaging Glucose in Tumors." In Chemical Exchange Saturation Transfer Imaging. Pan Stanford Publishing, 2017. http://dx.doi.org/10.1201/9781315364421-18.

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