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1

Brenda, Kamila L. Tavares, de Souza P. Brito Yasmin, Cristina Rezende Carla, and Alves Braga Flaviany. "EFEITOS DA PLASMAPORAÇÃO NA REGIÃO VULVAR." Revistaft 28, no. 135 (2024): 35. https://doi.org/10.5281/zenodo.11533235.

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O jato de plasma &eacute; utilizado em processos de&nbsp; rejuvenescimento da pele, onde por meio de descargas de energia&nbsp; el&eacute;trica, promove uma pequena les&atilde;o no tecido e dessa forma induz a produ&ccedil;&atilde;o de col&aacute;geno.&nbsp;<strong>OBJETIVOS</strong>: Avaliar os efeitos do jato de&nbsp; plasma associado &agrave; vitamina C e &agrave; gluconolactona no aspecto da&nbsp; genit&aacute;lia feminina; observar a textura da &aacute;rea aplicada antes e depois&nbsp; dos dois grupos, bem como os efeitos e a pigmenta&ccedil;&atilde;o da &aacute;rea&nbsp; aplicada.&nbsp;<
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2

van Dijken, Johannes P., Arjen van Tuijl, Marijke A. H. Luttik, Wouter J. Middelhoven та Jack T. Pronk. "Novel Pathway for Alcoholic Fermentation of δ-Gluconolactone in the Yeast Saccharomyces bulderi". Journal of Bacteriology 184, № 3 (2002): 672–78. http://dx.doi.org/10.1128/jb.184.3.672-678.2002.

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ABSTRACT Under anaerobic conditions, the yeast Saccharomyces bulderi rapidly ferments δ-gluconolactone to ethanol and carbon dioxide. We propose that a novel pathway for δ-gluconolactone fermentation operates in this yeast. In this pathway, δ-gluconolactone is first reduced to glucose via an NADPH-dependent glucose dehydrogenase (EC 1.1.1.47). After phosphorylation, half of the glucose is metabolized via the pentose phosphate pathway, yielding the NADPH required for the glucose-dehydrogenase reaction. The remaining half of the glucose is dissimilated via glycolysis. Involvement of this novel p
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3

Batsios, Georgios, Pavithra Viswanath, Celine Taglang та ін. "TBMT-01. HYPERPOLARIZED δ-[1-13C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO". Neuro-Oncology Advances 3, Supplement_1 (2021): i20. http://dx.doi.org/10.1093/noajnl/vdab024.083.

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Abstract Telomerase reverse transcriptase (TERT) expression is essential for tumor proliferation and is an attractive therapeutic target for gliomas. TERT expression has previously been shown to enhance glucose flux via the pentose phosphate pathway (PPP) in low grade gliomas expressing TERT. Hyperpolarized δ-[1-13C]gluconolactone has been used to detect flux via the PPP by monitoring its conversion to 6-phospho-[1-13C]gluconate (6PG) in isolated perfused liver. The goal of our study was to evaluate whether hyperpolarized δ-[1-13C]gluconolactone can be used to monitor elevated PPP flux induced
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4

Batsios, Georgios, Pavithra Viswanath, Peng Cao та ін. "CBMT-08. IN VIVO EVALUATION OF PENTOSE PHOSPHATE PATHWAY ACTIVITY IN ORTHOTOPIC GLIOMA USING HYPERPOLARIZED δ-[1-13C]GLUCONOLACTONE". Neuro-Oncology 21, Supplement_6 (2019): vi34. http://dx.doi.org/10.1093/neuonc/noz175.130.

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Abstract The pentose phosphate pathway (PPP) generates NADPH and ribose 5-phosphate, which are involved in the scavenging of reactive oxygen species and the synthesis of nucleotides. As such, the PPP is typically upregulated in cancer cells to address the metabolic needs of rapid cell proliferation. Imaging PPP upregulation could therefore be useful in tumor assessment. One intermediate of the pathway is 6-phospho-δ-gluconolactone (6P-δ-GL), which is produced by phosphorylation of δ-gluconolactone. 6P-δ-GL is further metabolized to 6-phospho-gluconate (6PG). The goal of our study was to evalua
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5

Arevalo, Maria J., Martin Avalos, Reyes Babiano та ін. "ChemInform Abstract: Optically Active Sugar Thioamides from δ-Gluconolactone." ChemInform 31, № 40 (2000): no. http://dx.doi.org/10.1002/chin.200040192.

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6

Todea, Anamaria, Emese Biro, Valentin Badea та ін. "Optimization of enzymatic ring-opening copolymerizations involving δ-gluconolactone as monomer by experimental design". Pure and Applied Chemistry 86, № 11 (2014): 1781–92. http://dx.doi.org/10.1515/pac-2014-0717.

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Abstract Enzymatic incorporation of carbohydrate-derived monomer units into hydrophobic polyester backbones represents a promising alternative to obtain new biodegradable oligomers and polymers. Immobilized lipases are efficient biocatalysts for copolymerization of β-butyrolactone and δ-gluconolactone, but only a systematic optimization study was able to highlight the influence of the main reaction parameters on the polymerization degree and on the relative copolymer content of the product. Therefore, experimental design was employed for determination of the optimal ring-opening copolymerizati
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7

Minami, Noriaki, Donghyun Hong, Celine Taglang та ін. "TMET-12. HYPERPOLARIZED Δ- [1-13C] GLUCONOLACTONE IMAGING VISUALIZES TERT-ASSOCIATED CHANGES IN DYNAMIC PENTOSE PHOSPHATE PATHWAY METABOLISM IN GLIOBLASTOMA". Neuro-Oncology 24, Supplement_7 (2022): vii264. http://dx.doi.org/10.1093/neuonc/noac209.1017.

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Abstract BACKGROUND TERT promoter mutations are a hallmark of glioblastoma (GBM). We recently reported that the expression of TERT and its upstream transcriptional factor, GABPB1, are strongly correlated with redox in GBM with TERT promoter mutations. However, further imaging biomarkers which visualize redox-associated metabolism and TERT expression are needed. Here we demonstrate that 13C magnetic resonance spectroscopy (MRS) of hyperpolarized δ-[1-13C] gluconolactone metabolism is a useful imaging tool to visualize changes in dynamic pentose phosphate pathway (PPP) metabolism that reflect TE
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8

Ohtake, Hiro, and Shiro Ikegami. "ChemInform Abstract: Facile Ring Transformation from Gluconolactone to Cyclitol Derivative via Spiro Sugar Orthoester." ChemInform 31, no. 21 (2010): no. http://dx.doi.org/10.1002/chin.200021210.

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9

Zhao, Ruitong, Xin Wang, Peng Wang, et al. "Experimentally monitoring of the rapid biomolecular hydrolysis reaction with optical weak measurement." Laser Physics 32, no. 12 (2022): 125201. http://dx.doi.org/10.1088/1555-6611/aca028.

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Abstract The real-time measurement of optical activity is of great significance for studying the chemical reactions of chiral molecules. In this study, we have built a set of linear common path optical weak measurement chiral sensor system in frequency domain, and the optical sensitivity of the system feasibly reaches 1524 for activity. Using this system, we have realized the state measurement of the ultrafast alkaline hydrolysis reaction of gluconolactone under different concentrations of catalyst. This study shows that the optical weak measurement chiral sensor can well monitor and compare t
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10

Mashige, F., N. Hisae, S. Toyota, S. Yoshinoya, and A. Ohkubo. "Sensitive, simple staining method for use in electrophoretic determination of amylase isoenzymes in serum." Clinical Chemistry 35, no. 12 (1989): 2322–25. http://dx.doi.org/10.1093/clinchem/35.12.2322.

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Abstract We have developed a sensitive and simple staining method for use in electrophoretic analysis of serum alpha-amylase (EC 3.2.1.1) isoenzymes. The principle of this method is as follows. alpha-Amylase hydrolyzes 4-nitrophenylmaltoheptaoside to generate oligosaccharide, which is then converted to gluconolactone in the presence of oligosaccharide dehydrogenase (no EC no. assigned), with concomitant reduction of 1-methoxy-5-methylphenazinium methylsulfate (1-m-PMS) to 1-m-PMSH. The hydrogen in 1-m-PMSH is then transferred to 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide to y
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11

Puri, R. N., F. X. Zhou, R. F. Colman, and R. W. Colman. "Plasmin-induced platelet aggregation is accompanied by cleavage of aggregin and indirectly mediated by calpain." American Journal of Physiology-Cell Physiology 259, no. 6 (1990): C862—C868. http://dx.doi.org/10.1152/ajpcell.1990.259.6.c862.

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We recently reported that thrombin-induced platelet aggregation 1) is accompanied by cleavage of aggregin, a 100-kDa membrane protein and a putative ADP receptor, 2) is indirectly mediated by intracellularly activated calpain, and 3) requires the occupancy of high-affinity thrombin receptors. Because of the similarities between responses after platelet activation induced by thrombin and plasmin (greater than or equal to 1.0 casein unit/ml), we investigated whether or not plasmin-induced platelet aggregation proceeds by the same mechanism that underlies thrombin-induced platelet aggregation. We
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12

Salusjärvi, Tuomas, Nisse Kalkkinen, and Andrei N. Miasnikov. "Cloning and Characterization of Gluconolactone Oxidase of Penicillium cyaneo-fulvum ATCC 10431 and Evaluation of Its Use for Production of d-Erythorbic Acid in Recombinant Pichia pastoris." Applied and Environmental Microbiology 70, no. 9 (2004): 5503–10. http://dx.doi.org/10.1128/aem.70.9.5503-5510.2004.

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ABSTRACT A d-erythorbic acid-forming soluble flavoprotein, gluconolactone oxidase (GLO), was purified from Penicillium cyaneo-fulvum strain ATCC 10431 and partially sequenced. Peptide sequences were used to isolate a cDNA clone encoding the enzyme. The cloned gene (accession no. AY576053 ) exhibits high levels of similarity with the genes encoding other known eukaryotic lactone oxidases and also with the genes encoding some putative prokaryotic lactone oxidases. Analysis of the coding sequence of the GLO gene indicated the presence of a typical secretion signal sequence at the N terminus of GL
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13

Batsios, Georgios, Celine Taglang, Anne Marie Gillespie та Pavithra Viswanath. "Imaging TERT expression in oligodendrogliomas using hyperpolarized δ-[1- 13C]-gluconolactone". Neuro-Oncology Advances, 21 липня 2023. http://dx.doi.org/10.1093/noajnl/vdad092.

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Abstract Background Telomere maintenance by telomerase reverse transcriptase (TERT) is essential for immortality in most cancers, including oligodendrogliomas. Agents that disrupt telomere maintenance such as the telomere uncapping agent 6-thio-2’-deoxyguanosine (6-thio-dG) are in clinical trials. We previously showed that TERT expression in oligodendrogliomas is associated with upregulation of glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the pentose phosphate pathway. We also showed that hyperpolarized δ-[1- 13C]-gluconolactone metabolism to 6-phosphogluconate (6-PG)
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14

Shing, Tony K. M., та Hau M. Cheng. "ChemInform Abstract: Short Syntheses of Gabosine I and Gabosine G from δ-D-Gluconolactone." ChemInform 39, № 1 (2008). http://dx.doi.org/10.1002/chin.200801191.

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15

Çelen Yücetürk, Selma, та Ayşe Dilek Azaz. "Production, purification, and determination of the biochemical properties of β-glucosidase in Trichoderma koningii via solid substrate fermentation". Zeitschrift für Naturforschung C, 23 квітня 2024. http://dx.doi.org/10.1515/znc-2024-0026.

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Abstract The β-glucosidase enzyme was obtained from Trichoderma koningii Oudem. NRRL 54330 under optimal conditions by solid substrate fermentation (SSF) using corn cobs as substrate. The enzyme was purified by two-step procedures, ammonium sulphate precipitation and cefarose-4B-l-tyrosine-1-naphthylamine hydrophobic interaction chromatography, followed by biochemical and kinetic characterisation. The β-glucosidase was obtained from T. koningii using ground corn cob as substrate and Na2HPO4, pH 9, as humidification medium. The optimum conditions for enzyme production by SSF were 30 °C and 6 da
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16

Koukouviti, Eleni, Alexios K. Plessas, Varvara Pagkali, Anastasios Economou, Giannis S. Papaefstathiou, and Christos Kokkinos. "3D-printed electrochemical glucose device with integrated Fe(II)-MOF nanozyme." Microchimica Acta 190, no. 7 (2023). http://dx.doi.org/10.1007/s00604-023-05860-6.

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AbstractEstimation of glucose (GLU) levels in the human organism is very important in the diagnosis and monitoring of diabetes. Scientific advances in nanomaterials have led to the construction of new generations of enzymatic-free GLU sensors. In this work, an innovative 3D-printed device modified with a water-stable and non-toxic metal–organic framework of iron (Fe(II)-MOF), which serves as a nanozyme, has been developed for the voltammetric determination of GLU in artificial sweat. In contrast to existing MOF-based GLU sensors which exhibit electrocatalytic activity for the oxidation of GLU
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17

Duan, Zhihang, Changlian Gan, Jianjun Yue, et al. "Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia." Journal of Analytical Science and Technology 16, no. 1 (2025). https://doi.org/10.1186/s40543-025-00486-0.

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Abstract Amomum villosum Lour. is an essential plant for both consumption and healing purposes. Among all the regions in China where A. villosum is grown, Yangchun City is widely regarded as the most ideal habitat for this plant. However, there were rare studies that explored the differential metabolites between Yangchun and other regions of A. villosum fruits. The current study analyzed the metabolic profiles of A. villosum fruit samples cultivated in four representative producing areas. As a result, 260 differentially accumulated metabolites were identified in the GDYC-F versus LW-F. A total
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Ming, Yue, Guoqiang Li, Zhuangzhuang Shi та ін. "Co-utilization of glucose and xylose for the production of poly-β-hydroxybutyrate (PHB) by Sphingomonas sanxanigenens NX02". Microbial Cell Factories 22, № 1 (2023). http://dx.doi.org/10.1186/s12934-023-02159-2.

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Abstract Background Poly-β-hydroxybutyrate (PHB), produced by a variety of microbial organisms, is a good substitute for petrochemically derived plastics due to its excellent properties such as biocompatibility and biodegradability. The high cost of PHB production is a huge barrier for application and popularization of such bioplastics. Thus, the reduction of the cost is of great interest. Using low-cost substrates for PHB production is an efficient and feasible means to reduce manufacturing costs, and the construction of microbial cell factories is also a potential way to reduce the cost. Res
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