Academic literature on the topic 'Glucosamine'

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Journal articles on the topic "Glucosamine"

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Gening, Marina L., Yury E. Tsvetkov, Denis V. Titov, Alexey G. Gerbst, Olga N. Yudina, Alexey A. Grachev, Alexander S. Shashkov, et al. "Linear and cyclic oligo-β-(1→6)-D-glucosamines: Synthesis, conformations, and applications for design of a vaccine and oligodentate glycoconjugates." Pure and Applied Chemistry 85, no. 9 (September 1, 2013): 1879–91. http://dx.doi.org/10.1351/pac-con-12-09-06.

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Poly-β-(1→6)-N-acetyl-D-glucosamine is an exopolysaccharide secreted by numerous pathogenic bacteria, includingStaphylococcus aureus,Escherichia coli,Yersinia pestis,Bordetella pertussis,Acinetobacter baumannii,Burkholderiaspp., and others. A convergent approach was developed for the synthesis of oligosaccharide fragments consisting of 5, 7, 9, and 11 glucosamine orN-acetylglucosamine units and for the preparation of five nona-β-(1→6)-D-glucosamines with variousN-acetylation patterns. Penta- and nona-β‑(1→6)-D-glucosamines conjugated to protein carriers through a specially developed sulfhydryl linker proved to be highly immunogenic in mice and rabbits and elicited antibodies that mediated opsonic killing of multiple strains ofS. aureus(including methicillin-resistantS. aureus, MRSA) andE. coli, and protected againstS. aureusskin abscesses and lethalE. coliandB. cenocepaciaperitonitis. These findings provide a basis for the construction of a unique semisynthetic vaccine against multiple bacterial targets. Conformational studies by means of special NMR experiments and computer modeling revealed that the oligo-β-(1→6)-D-glucosamine chain exists mostly in a helix-like conformation, where the terminal monosaccharides are arranged close to each other. Owing to this feature, oligoglucosamines consisting of 2 to 7 residues easily form products of cycloglycosylation. Cyclooligo-β-(1→6)-D-glucosamines represent a new family of functionalized cyclic oligosaccharides. Owing to their molecular architectonics, these compounds are convenient scaffolds for the design of conjugates with defined valency, symmetry, flexibility, and function.
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TAKIGUCHI, Yasuyuki, Ayako SHINA, and Tatsuaki YAMAGUCHI. "Bioconversion of D-glucosamine to D-glucosaminic acid." Journal of the agricultural chemical society of Japan 77, no. 6 (2003): 576–78. http://dx.doi.org/10.1271/nogeikagaku1924.77.576.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1167 (September 2007): 15. http://dx.doi.org/10.2165/00128415-200711670-00045.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1361 (July 2011): 23–24. http://dx.doi.org/10.2165/00128415-201113610-00081.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1205 (June 2008): 13. http://dx.doi.org/10.2165/00128415-200812050-00037.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1110 (July 2006): 10. http://dx.doi.org/10.2165/00128415-200611100-00030.

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Matheson, Anna J., and Caroline M. Perry. "Glucosamine." Drugs & Aging 20, no. 14 (2003): 1041–60. http://dx.doi.org/10.2165/00002512-200320140-00004.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1262 (July 2009): 14. http://dx.doi.org/10.2165/00128415-200912620-00043.

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&NA;. "Glucosamine." Reactions Weekly &NA;, no. 1033 (January 2005): 8. http://dx.doi.org/10.2165/00128415-200510330-00018.

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Barclay, Teresa Susanne, Candy Tsourounis, and Gary M. McCart. "Glucosamine." Annals of Pharmacotherapy 32, no. 5 (May 1998): 574–79. http://dx.doi.org/10.1345/aph.17235.

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OBJECTIVE: To review the pharmacology and pharmacokinetics of glucosamine and critically evaluate currently available literature regarding its safety and efficacy. DATA SOURCE: A MEDLINE search was conducted between January 1965 and May 1997. Key words used in the search were osteoarthritis, osteoarthrosis, gonarthrosis, and glucosamine. In addition, references cited in articles obtained from the MEDLINE search were reviewed for additional literature. STUDY SELECTION AND DATA EXTRACTION: All articles were considered for inclusion in the review. Articles were excluded from critical evaluation for lack of randomization, lack of a control group, 30 or fewer study participants, inconsistent treatment regimen, incomplete dosing information, or incomplete reporting of results. DATA SYNTHESIS: Osteoarthritis affects approximately 12% of the US population; the incidence increases with increasing age. Currently used pharmacologic treatments, including acetaminophen and nonsteroidal antiinflammatory drugs, do not slow or reverse the degenerative process in osteoarthritis. Glucosamine has recently received a great deal of attention from the public as a potential treatment of osteoarthritis, prompting healthcare professionals to investigate its clinical usefulness and potential for adverse effects. The drug has been proposed to stop and possibly reverse the degenerative process in osteoarthritis. Following absorption of an oral dose, glucosamine is incorporated into plasma proteins during first-pass metabolism, resulting in 26% bioavailability. Unbound glucosamine is concentrated in the articular cartilage. Each of the three critically evaluated studies reported a decrease in the symptoms of osteoarthritis (e.g., decreased Lequesne index, decreased pain severity, increased range of motion) for the glucosamine group, which was greater than that obtained in the control group. Flaws in study design, however, prevent the use of these results in modifying current clinical practice. Reported short-term adverse effects include mild gastrointestinal problems, drowsiness, skin reactions, and headache. CONCLUSIONS: Improvement in the symptoms of osteoarthritis associated with the use of glucosamine has been observed in clinical trials; however, those trials have flaws in design and data analysis. Further research needs to be conducted before glucosamine can be recommended as a treatment for osteoarthritis.
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Dissertations / Theses on the topic "Glucosamine"

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Zhang, Xinfeng. "Nonenzymatic formation of advanced glycation endproducts by glucosamine autocondensation and glucosamine with proteins /." View online ; access limited to URI, 2003. http://0-wwwlib.umi.com.helin.uri.edu/dissertations/dlnow/3112135.

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Fox, Beth Anne, Evan D. Schmitz, and Rick L. Wallace. "Glucosamine and Chondroitin for Osteoarthritis." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/8684.

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Bazito, Reinaldo Camino. "Novos tensoativos derivados da 2-D-glucosamina." Universidade de São Paulo, 2001. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-12092006-143935/.

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Foram sintetizadas duas novas séries de tensoativos de açúcar derivados da 2-D-glucosamina: os metil 2-acilamido-2-deóxi-6-O-sulfonato-D-glucopiranosídeos de sódio (aniônicos) e os cloretos de metil 2-acilamido-2,6-dideóxi-6-trimetilamônio-D-glucopiranosídeos (catiônicos). Os tensoativos aniônicos foram obtidos pela acilação da 2-D-glucosamina com cloretos de acila (com 8, 12 e 16 carbonos), seguida pela metilação desses derivados com metanol em meio ácido, e posterior sulfatação dos metil glucosídeos com complexo trióxido de enxofre-piridina. Os tensoativos catiônicos foram obtidos pela tosilação dos metil glucosídeos, seguida pela quaternização com trimetilamina e troca do contra-íon tosilato por cloreto com resina de troca-iônica. Esses tensoativos apresentaram c.m.c. similares a de outros tensoativos iônicos de cadeia hidrofóbica de igual comprimento, mas energias livres de transferência do grupo polar para a micela muito mais favoráveis. Esse fato foi atribuído à formação de ligações de hidrogênio entre os grupos polares do tensoativo na micela, e à hidrofobicidade do açúcar. As micelas formadas apresentaram números de agregação maiores que os obtidos para outros tensoativos, provavelmente devido às interações atrativas entre os grupos polares.
Two new sugar-based surfactant series were synthesized from 2-D-glucosamine: sodium methyl 2-acylamido-2-deoxi-6-O-sulfonate-D-glucopyranosides (anionic) and methyl 2-acylamido-2,6-dideoxi-6-trimethylamonium-D-glucopyranoside chlorides (cationic). The anionic surfactants were obtained by the acylation of 2-D-glucosamine with acyl chlorides (with 8, 12 and 16 carbons), followed by the methylation of these derivatives with methanol in acidic media, and the sulfation of the methyl glucosides with sulfur trioxide-pyridine complex. The cationic surfactants were obtained by the tosylation of methyl glucosides followed by the quaternization with trimethylamine and exchange of the tosylate contra-ion with chloride ions on an ion exchange resin. These surfactants showed c.m.c. similar to other ionic surfactants with equal hydrophobic chain lengths, but more favorable free energies of transfer of the polar head to the micelle. This fact is attributed to hydrogen bonding between the head groups of the surfactant in the micelle, and the hydrophobicity of the sugar moiety. The micelles of these surfactants showed aggregation numbers larger than those obtained for other surfactants, problably because of head-group attractive interactions.
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Gentil, Emmanuel. "Utilisation de dérivés 2-alkoxycarbonyles du d-glucose et de la d-glucosamine en synthèse glycosidique." Lyon 1, 1990. http://www.theses.fr/1990LYO10229.

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Ce travail a permis d'estimer l'influence de la nature d'un groupe participant alkoxycarbonyle en synthese glycosidique a partir du d-glucose et de la d-glucosamine. Dans une premiere partie, les donnees de la litterature concernant le role et l'importance des orthoesters dans les reactions de glycosylations de type koenigs-knorr ainsi que l'utilisation de derives 2-o-alkoxycarbonyles du d-glucose en synthese glucosidique ont ete analysees. La synthese stereoselective, l'analyse structurale et les rearrangements acido-catalyses d'1,2-orthocarbonates ont ensuite ete exposes. Cette etude a permis une interpretation mecanistique des reactions de glycosylation des derives 2-o-alkoxycarbonyles du d-glucose qui differe de celle avancee pour les analogues esterifies. Le mecanisme reactionnel suppose un intermediaire de type alkoxydioxocarbenium dont la participation, suivie de l'attaque de l'alcool, conduit aux -d-glucosides et aux orthocarbonates par deux chemins reactionnels independants. Dans une deuxieme partie, apres commentaires des donnees bibliographiques concernant les methodes de glycosylations appliquees a la synthese de (1-4) glycosides derives de la d-glucosamine, des accepteurs de glycosyle n-allyloxycarbonyles derives de la d-glucosamine, ont ete synthetises par diverses voies. Lors des reactions de glycosylations avec les donneurs 2-n-allyloxycarbonyles derives de la d-glucosamine, ces accepteurs se sont montres tres peu reactifs. Cette faible reactivite inattendue pourrait etre la consequence d'un effet particulier du groupement protecteur 2-allyloxycarbonylamine des accepteurs
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Brown, Martin F. "Glucosamine synthetase inhibitors : synthesis, kinetics and antibacterial properties." Thesis, Queen's University Belfast, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317549.

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Munoz, Nicole. "Glucosamine reduces glycogen storage in L6 skeletal muscle cells." Online access for everyone, 2007. http://www.dissertations.wsu.edu/Thesis/Fall2007/n_munoz_112507.pdf.

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Marie, Corinne. "Roles of two Rhizobium leguminosarum glucosamine synthases in symbiosis." Thesis, University of East Anglia, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334333.

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Blackwell, Amy Marie. "GLUCOSAMINE AND INSULIN RESISTANCE: A SYNTHESIS OF CURRENT RESEARCH." Thesis, The University of Arizona, 2003. http://hdl.handle.net/10150/609992.

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In the early 1980's, Glucosamine Sulfate was introduced as a non -FDA approved, herbal supplement for the treatment of oteoarthritis (Adams, 1999).Preliminary evidence shows that long -term use of Glucosamine can slow joint space narrowing caused by osteoarthritis (Adams). Animal studies were conducted to assess the effectiveness and mechanisms of action of glucosamine. Glucosamine's insulin resistant property was discovered during the animal studies. The purpose of this project was to conduct a review of the literature to determine if there was enough human anecdotal and /or rat empirical data to warrant further study in humans on the impact of glucosamine on insulin resistance. Data gathered in this project provided evidence that glucosamine leads to insulin resistance in animals. Awareness of the insulin resistant properties of glucosamine noted in animal studies, coupled with the lack of well -controlled studies of effect and impact on humans, demonstrates the need to continue study in humans to determine the effect of glucosamine on insulin resistance in humans.
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Renaud, Anne-Laure. "Réactions stéréosélectives basées sur des dérivés de la glucosamine." Université Louis Pasteur (Strasbourg) (1971-2008), 2001. http://www.theses.fr/2001STR13199.

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Ce travail s'inscrit dans le cadre de la recherche de nouveaux auxiliaires chiraux basés sur des sucres, dont les modes d'action seraient basés sur des interactions non covalentes. Des dérivés de la glucosamine portant à la fois une insaturation (double liaison allylique ou énolate) et un groupe aromatique ont été préparés. Une interaction de type p ou une liaison hydrogène entre ces deux éléments liés au sucre devait permettre de bloquer une des faces diastéréotopiques de l'insaturation et n'autoriser l'accès du réactif que sur une seule face. Dans la première approche, des allylglucosamines portant différents groupes N-protecteurs ont été préparées et soumises à des réactions d'époxydation avec différents oxydants. La stéréosélectivité de ces réactions variait de 4 à 72% d'excès diastéréomérique. Les méthodes mises au point ont été appliquées à la synthèse d'un inhibiteur potentiel de glycosidases. Dans une deuxième approche, des N-acylglycosamines portant un groupe aromatique en position anomérique ont été synthétisées puis aldolisées en milieu basique. La sélectivité de ces réactions a parfois atteint 40%, mais l'origine de cette sélectivité n'a pas pu être totalement rationalisée. L'ensemble de ces résultats a permis de mettre au point différentes méthodes de synthèse applicables à la chimie très particulière de la glucosamine
This work concerns the search for new chiral auxiliaries based on carbohydrates, using non-covalent interactions. Glucosamine derivatives bearing an insaturation (allylic double bond or enolate) and an aromatic group have been prepared. A p-interaction or a hydrogen bond between these two pendant groups had to be able to block one diastereotopic face of the insaturation. In a first approach, allylglucosamines bearing various N-protecting groups were prepared and epoxidized. The stereoselectivity of these reaction varied from 4 to 72% diastereomeric excess. The methods developped have been applied to the synthesis of a potential glycosidase inhibitor. In a second approach, N-acylglucosamines bearing an aromatic group at the anomeric position were synthesized and submitted to aldol reactions. The selectivity of these reactions reached 40% in some cases, but the origin of this selectivity could not be fully explained
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Dutta, Udayan. "Advanced glycation endproducts analysis of glucosamine with reducing sugars, DNA nucleosides and serum proteins /." View online ; access limited to URI, 2005. http://0-wwwlib.umi.com.helin.uri.edu/dissertations/dlnow/3188840.

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Books on the topic "Glucosamine"

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Sedgbeer, Sandra. Glucosamine & chondroitin: The arthritis solution. Loughton: Health Issues, 1998.

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Marie, Corinne. "Roles of two Rhizobium leguminosarum glucosamine synthases in symbiosis". Norwich: University of East Anglia, 1992.

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Parker, Philip M., and James N. Parker. Glucosamine: A medical dictionary, bibliography, and annotated research guide to Internet references. San Diego, CA: ICON Health Publications, 2004.

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Brenda, Adderly, and Fox Barry, eds. The arthritis cure: The medical miracle that can halt, reverse, and may even cure osteoarthritis. New York: St. Martin's Griffin, 1998.

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Brenda, Adderly, and Fox Barry, eds. Maximizing the arthritis cure: A step-by-step program to faster, stronger healing during any stage of the cure. New York: St. Martin's Press, 1998.

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Theodosakis, Jason. Maximizing the arthritis cure: A step-by-step program to faster, stronger healing during any stage of the cure. London: Century, 1998.

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Kinzy, Willy. Die Trichloracetimidatmethode zur Synthese von Glycokonjugaten mit Glucosamin als Komponente. Konstanz: Hartung-Gorre, 1986.

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Brenda, Adderly, and Fox Barry, eds. The arthritis cure: The medical miracle that can halt, reverse, and may even cure osteoarthritis. New York: St. Martin's Press, 1997.

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Brenda, Adderly, and Fox Barry, eds. The arthritis cure: The medical breakthrough that can halt, reverse, and even cure osteoarthritis. London: Century, 1997.

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Brenda, Adderly, and Fox Barry, eds. Guan jie yen liao fa: The Arthritis cure. Taibei Shi: Di teng chu ban tu shu yu xian gong si, 1998.

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Book chapters on the topic "Glucosamine"

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Bährle-Rapp, Marina. "Glucosamine." In Springer Lexikon Kosmetik und Körperpflege, 225. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4287.

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Bährle-Rapp, Marina. "Acetyl Glucosamine." In Springer Lexikon Kosmetik und Körperpflege, 5. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_83.

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Bährle-Rapp, Marina. "Glucosamine HCL." In Springer Lexikon Kosmetik und Körperpflege, 225. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4288.

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Schomburg, Dietmar, and Dörte Stephan. "Glucosamine kinase." In Enzyme Handbook 13, 601–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-59176-1_120.

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Schomburg, Dietmar, and Dörte Stephan. "Glucosamine N-acetyltransferase." In Enzyme Handbook 11, 603–5. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_135.

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Li, Jie Jack. "Amadori glucosamine rearrangement." In Name Reactions, 7. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_5.

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Schomburg, Dietmar, and Dörte Stephan. "Glucosamine-phosphate N-acetyltransferase." In Enzyme Handbook 11, 607–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_136.

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Schomburg, Dietmar, and Dörte Stephan. "Heparin-glucosamine 3-O-sulfotransferase." In Enzyme Handbook, 1017–19. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-59025-2_190.

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Jain, Tanvi, Hridyesh Kumar, and Pradip Kumar Dutta. "D-Glucosamine and N-Acetyl D-Glucosamine: Their Potential Use as Regenerative Medicine." In Springer Series on Polymer and Composite Materials, 279–95. New Delhi: Springer India, 2015. http://dx.doi.org/10.1007/978-81-322-2511-9_11.

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Dennis, James W. "Glucosamine-6 Phosphate N-Acetyltransferase (GNPNAT1/GNA1)." In Handbook of Glycosyltransferases and Related Genes, 1481–88. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54240-7_148.

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Conference papers on the topic "Glucosamine"

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Peña, Isabel, José Alonso, Alcides Simao, Matías Berdakin, Celina Bermúdez, Carlos Cabezas, and Lucie Kolesniková. "THE CONFORMATIONAL BEHAVIOUR OF GLUCOSAMINE." In 69th International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2014. http://dx.doi.org/10.15278/isms.2014.td09.

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Wen, Zhao. "Application and research progress of glucosamine." In INTERNATIONAL SYMPOSIUM ON THE FRONTIERS OF BIOTECHNOLOGY AND BIOENGINEERING (FBB 2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5110844.

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Camargo, Lilian Tatiane F. de M., and Ademir J. Camargo. "Estudo Teórico do Mecanismo de Complexação do Íon Cobalto II com a Glucosamina Usando Dinâmica Molecular de Car-Parrinello." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol202091.

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Cobalt II is essential for the body and is one of the components of vitamin B12. However, in excess, it is toxic. It is present in various industrial and nuclear reactor waste; removing it is necessary. Among the various processes for removing heavy metals from wastewater, adsorption stands out, economical, easy to apply, and efficient. Modified chitosan has shown promise in the adsorption of cobalt II from contaminated waters. Although experimental studies show cobalt II adsorption by chitosan, the adsorption mechanism by chitosan is still unclear. This work aimed to study cobalt coordination with glucosamine (chitosan monomer) in the gas phase and aqueous solvation using the Car-Parrinello Molecular Dynamics. The results show that cobalt can coordinate strongly with the amino group of glucosamine in both the gaseous and aqueous environments. The QTAIM analysis was performed to characterize the interactions. In the gas phase, a partially covalent interaction was observed, while in the aqueous medium, the interaction of Co with glucosamine can be classified as covalent. Understanding the coordination mechanism of cobalt II with glucosamine can help remove cobalt from wastewater.
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Eshwaran, R., M. Kolibabka, K. Kohl, HP Hammes, T. Wieland, and Y. Feng. "Glucosamine is neuroprotective in the diabetic retina." In Diabetes Kongress 2019 – 54. Jahrestagung der DDG. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1688259.

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Leguijt, Robin, Hartmut Redlich, and Par Winkelmann. "NOVEL COMPOUNDS AND REACTIONS OF GLUCOSAMINE TRIMETHYLENEDITHIOACETALS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.608.

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Mantovani, LG, A. Belisari, C. Cristoforetti, G. Giacovelli, and LC Rovati. "SAT0088 Cost-benefit analysis of glucosamine sulfate use." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.463.

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Petitou, M., J. C. Lormeau, and J. Choay. "AT III BINDING SITE OF HEPARIN. DETERMINATION OF THE ROLE OF SULFATE GROUPS AT THE REDUCING-END DISACCHARIDE THROUGH NEW SYNTHETIC PENTASACCHARIDES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642826.

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A unique sequence is required in heparin for binding to antithrombin III (AT III) and eliciting anti-factor Xa activity. We have previously synthesized a pentasaccharide containing all the structural features of this sequence. It binds to AT III with the same affinity as high affinity heparin. The complex thus formed has a high anti-factor Xa activity. We have now synthesized a new series of α-methylated pentasaccharides which better mimic the naturally occurring configuration at C1 of the reducing-end glucosamine unit. The synthesis of the inactive pentasaccharide II allowed us to confirm in this series the essential role of the 3-sulfate group borne by glucosamine unit F. Wehave also particularly addressed the still unanswered question regarding the role of the 2-sulfate group borne by iduronic acid G and of the 6-sulfate group borne by glucosamine unit H. Pentasaccharides III and IV elicit the same anti-factor Xa activity which is substantially decreased as compared to I. A similar decrease has been recently reported for pentasaccharide V (T. Beetz & C.A.A. van Boeckel, Tetrahedron Lett., 1986, 27, 5889). We therefore conclude that the presence of both these sin fate groups is required for full expression of the antifactor Xa activity.
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Shuqin Zhang, Fei Huang, Yaojie Li, Yanli Zhao, and Yan Xu. "Synthesis and characterization of D-glucosamine Complexes with Lead(II)." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5965328.

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Sulman, Esther. "NI IMPREGNATED INTO HYPERCROSSLINKED POLYSTYRENE IN N-METHYL-D-GLUCOSAMINE SYNTHESIS." In 18th International Multidisciplinary Scientific GeoConference SGEM2018. Stef92 Technology, 2018. http://dx.doi.org/10.5593/sgem2018/4.1/s17.066.

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Shi, Changcheng, Dongshan Wei, Chunlei Du, Hongliang Cui, and Yuting Ma. "Characterization of Glucosamine and Collagen crystallization by terahertz time-domain spectroscopy." In 2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO). IEEE, 2016. http://dx.doi.org/10.1109/3m-nano.2016.7824982.

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Reports on the topic "Glucosamine"

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Sivordova, L. E., J. V. Polyakova, Y. R. Akhverdyan, and B. V. Zavodovsky. EFFECTIVENESS OF TRANSDERMAL GLUCOSAMINE COMPLEX IN COMBINED THERAPY OF GONARTHROSIS. Планета, 2018. http://dx.doi.org/10.18411/978-5-907109-24-7-2018-xxxv-257-260.

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Shibata, Yoshimi. Oral Administration of N-Acetyl-D Glucosamine Polymer Particles Down-Regulates Airway Allergic Responses. Fort Belvoir, VA: Defense Technical Information Center, March 2005. http://dx.doi.org/10.21236/ada442684.

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Shibata, Yoshimi. Oral Administration of N-acetyl-D Glucosamine Polymer Particles Down-Regulates Airway Allergic Responses. Fort Belvoir, VA: Defense Technical Information Center, May 2008. http://dx.doi.org/10.21236/ada484241.

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Shibata, Yoshimi. Oral Administration of N-Acetyl-D Glucosamine Polymer Particles Down-Regulates Airway Allergic Responses. Fort Belvoir, VA: Defense Technical Information Center, March 2006. http://dx.doi.org/10.21236/ada454070.

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Shibata, Yoshimi. Oral Administration of N-Acetyl-D-Glucosamine Polymer Particles Down-Regulates Airway Allergic Responses. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ada469207.

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Shibata, Yoshimi. Oral Administration of a N-Acetyl-D-Glucosamine Polymer Particles Down-Regulates Airway Allergic Responses. Fort Belvoir, VA: Defense Technical Information Center, March 2004. http://dx.doi.org/10.21236/ada424227.

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Olszewski, Neil, and David Weiss. Role of Serine/Threonine O-GlcNAc Modifications in Signaling Networks. United States Department of Agriculture, September 2010. http://dx.doi.org/10.32747/2010.7696544.bard.

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Abstract:
Significant evidence suggests that serine/threonine-O-linked N-acetyl glucosamine0-(GlcNAc) modifications play a central role in the regulation of plant signaling networks. Forexample, mutations in SPINDLY,) SPY (an O-GlcNAc transferase,) OGT (promote gibberellin GA) (signal transduction and inhibit cytokinin responses. In addition, mutating both Arabidopsis OGTsSEC (and SPY) causes embryo lethality. The long-term goal of this research is to elucidate the mechanism by which Arabidopsis OGTs regulate signaling networks. This project investigated the mechanisms of O-GlcNAc regulation of cytokinin and gibberellin signaling, identified additional processes regulated by this modification and investigated the regulation of SEC activity. Although SPY is a nucleocytoplasmic protein, its site of action and targets were unknown. Severalstudies suggested that SPY acted in the nucleus where it modified nuclear components such as the DELLA proteins. Using chimeric GFP-SPY fused to a nuclear-export signal or to a nuclear-import signal, we showed that cytosolic, but not nuclear SPY, regulated cytokinin and GA signaling. We also obtained evidence suggesting that GA and SPY affect cytokinin signaling via a DELLA-independent pathway. Although SEC and SPY were believed to have overlapping functions, the role of SEC in cytokinin and GA signaling was unclear. The role of SEC in cytokinin and GA responses was investigated by partially suppressing SPY expression in secplants using a synthetic Spymicro RNA miR(SPY). The possible contribution of SEC to the regulation of GA and cytokinin signaling wastest by determining the resistance of the miR spy secplants to the GA biosynthesis inhibitor paclobutrazol and to cytokinin. We found that the transgenic plants were resistant to paclobutrazol and to cytokinin, butonlyata level similar to spy. Moreover, expressing SEC under the 35S promoter in spy mutant did not complement the spy mutation. Therefore, we believe that SEC does not act with SPY to regulate GA or cytokinin responses. The cellular targets of Spy are largely unknown. We identified the transcription factor TCP15 in a two-hybrid screen for SPY-interacting proteins and showed that both TCP15 and its closely homolog TCP14 were O-GlcNAc modified by bacterially-produced SEC. The significance of the interaction between SPY and these TCPs was examined by over-expressing the minwild-type and spy-4plants. Overexpression of TCP14 or TCP15 in wild-type background produced phenotypes typical of plants with increased cytokinin and reduced GA signaling. TCP14 overexpression phenotypes were strongly suppressed in the spy background, suggesting that TCP14 and TCP15 affect cytokinin and GA signaling and that SPY activates them. In agreement with this hypothesis, we created a tcp14tcp15 double mutant and found that it has defects similar to spyplants. In animals, O-GlcNAc modification is proposed to regulate the activity of the nuclear pore. Therefore, after discovering that SEC modified a nucleoporinNUP) (that also interacts with SPY, we performed genetic experiments exploring the relationship between NUPs and SPY nupspy double mutants exhibited phenotypes consistent with SPY and NUPs functioning in common processes and nupseeds were resistant to GA biosynthesis inhibitors. All eukaryotic OGTs have a TPR domain. Deletion studies with bacterially-expressed SEC demonstrated SEC'sTPR domain inhibits SEC enzymatic activity. Since the TPR domain interacts with other proteins, we propose that regulatory proteins regulate OGT activity by binding and modulating the inhibitory activity of the TPR domain.
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