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Dissertations / Theses on the topic 'Glucose'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Teutenberg, Kevin. "Glucose, glucose transporters and neurogenesis." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/28026.

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Since the pioneering work of Altman in the late 60's, much has been learned about the generation of neurons in the adult brains of several species, including mice, rats, and humans. An underlying assumption is that these newborn neurons acquire their energy, in the form of glucose, in a similar manner to mature neurons: via glucose transporters. Using BRDU and double immunohistochemistry, we investigated the relationship between hippocampal neurogenesis and glucose transporters, as well as monocarboxylate transporters. Unexpectedly, the results suggest that newborn neurons do not acquire their

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2

Sauer, Gudrun Anna. "Untersuchungen zum Glucose-Auswärtstransport des Na+/Glucose-Cotransporter [Na+/Glucose-Cotransporters] SGLT1." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965190358.

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3

Pasta, M. "GLUCOSE ELECTROOXIDATION." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150142.

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The electrooxidation of glucose has attracted a lot of interest due to its applications in blood glucose sensors and biological fuel cells. Glucose sensors optimization is highly necessary to improve the treatment of Diabetes Mellitus, a chronic disease affecting millions of people around the world, while biological fuel cells have been studied in order to explore new, renewable energy sources alternative to fossil fuels. There are three main ways to perform glucose electrooxidation, depending on the active oxidant agent or mediator employed: enzymatic electrooxidation utilizes enzymes such a

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4

Rapoport, Benjamin Isaac. "Glucose-powered neuroelectronics." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/66460.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 157-164).<br>A holy grail of bioelectronics is to engineer biologically implantable systems that can be embedded without disturbing their local environments, while harvesting from their surroundings all of the power they require. As implantable electronic devices become increasingly prevalent in scientific research and in the diagnosis, management, and treatment of human disease, there is correspo

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5

Pennant, Mary Elizabeth. "Measuring glucose metabolism." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611215.

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6

Pawar, H. S. "Microbial glucose isomerase." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1988. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3305.

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7

Chen, Xuesong. "Impact of Continuous Glucose Monitoring System on Model Based Glucose Control." Thesis, University of Canterbury. Electrical and Computer Engineering, 2007. http://hdl.handle.net/10092/1228.

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Critically ill patients are known to experience stress-induced hyperglycemia. Inhibiting the physiological response to increased glycaemic levels in these patients are factors such as increased insulin resistance, increased dextrose input, absolute or relative insulin deficiency, and drug therapy. Although hyperglycemia can be a marker for severity of illness, it can also worsen outcomes, leading to an increased risk of further complications. Recent studies have shown that tight control can reduce mortality up to 43%. Metabolic modelling has been used to study physiological behaviour and/or

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8

D'Costa, E. J. "The application of quinoprotein glucose dehydrogenase in a biosensor for glucose." Thesis, Cranfield University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373985.

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9

Ng, Natasha Hui Jin. "The role of glucose-6-phosphatase catalytic domain in glucose homeostasis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:1e5fc469-d474-45e8-9a6b-6b56d1cd3b77.

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Over the past decade, there has been unprecedented increase in the number of genetic loci associating with type 2 diabetes (T2D) risk and related glycemic traits, thanks to advances in sequencing technologies and access to large sample sizes. Identification of associated genetic variants across the frequency spectrum can provide valuable insight into disease pathophysiology. However, the translation into biological insights has been slow often due to uncertainties over the underlying effector transcripts. G6PC2/ABCB11 is one locus characterised by common non-coding variants that are strongly a

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10

Jackson-Cenales, Oteka. "Best Practices for Glucose Management Using a Computer-Based Glucose Management." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4523.

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The prevalence of diabetes mellitus (DM) continues to be a global concern among health care practitioners. Without collaboration and interventions, this chronic disease, which poses a significant financial burden for health care institutions, will continue to be problematic. Promoting the use of glycemic control measures among diabetic patients is an intervention, which has the potential to reduce diabetic complications and improve outcomes. The purpose of this doctoral project was to explore available evidence through a systematic review of the best practices for glucose management. The chron

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11

Mersal, Gaber Ahmed Mahmoud. "Enzymatic and electrophoretic methods for carbohydrate determination using microsystems." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972095381.

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12

Choi, Kevin. "Glucose Kinetics of Hyperglycemic Rainbow Trout: Effects of Exogenous Glucose and Exercise." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32856.

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This thesis investigates the ability of rainbow trout to modulate hepatic glucose production (Ra) and disposal (Rd). My goals were to determine: (1) if resting trout can modulate fluxes to cope with exogenous glucose; (2) how fluxes change during graded swimming; (3) how exogenous glucose affects swimming kinetics; and (4) if exogenous glucose affects cost of transport or performance. Results show that resting trout suppress Ra completely and stimulate Rd from 10.6 to 27.6 μmol kg-1 min-1. During swimming, fluxes increase from 15.6 to 21.9 μmol kg-1 min-1, but only at speeds >2.4 BL s-1. When

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13

Lee, Brenda Minfei. "Effects of glucose, fructose and sucrose on postprandial glucose and insulin responses." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq28791.pdf.

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14

Talebi, Fard Sahba. "Glucose monitoring measuring blood glucose using vertical cavity surface emitting lasers (VCSELs)." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1509.

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Diabetes Mellitus is a common chronic disease that is an ever-increasing public health issue. Continuous glucose monitoring has been shown to help diabetes mellitus patients stabilize their glucose levels, leading to improved patient health. Hence, a glucose sensor, capable of continuous real-time monitoring, has been a topic of research for three decades. Current methods of glucose monitoring, however, require taking blood samples several times a day, hence patient compliance is an issue. Optical methods are one of the painless and promising methods that can be used for blood glucose predicti

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15

Chen, Ting. "The development and application of glucose electrodes based on "wired" glucose oxidase." Access restricted to users with UT Austin EID UMI Company copy, 2001. http://www.lib.utexas.edu/etd/r/d/2001/c4207.

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16

Hebert, Daniel N. "Glucose Transporter Oligomeric Structure Determines the Mechanism of Glucose Transport: A Dissertation." eScholarship@UMMS, 1991. https://escholarship.umassmed.edu/gsbs_diss/217.

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The relationship between human erythrocyte glucose transporter (GLUT1) oligomeric structure and function was studied. GLUT1 was purified from human erythrocytes in the absence (GLUT1-DTT) or the presence (GLUT1+DTT) of dithiothreitol. Chemical cross-linking studies of lipid bilayer-resident purified GLUT1 and hydrodynamic studies of cholate-solubilized GLUT1 support the view that GLUT1-DTT is a homotetramer and GLUT1+DTT is a homodimer. Parallel studies on human erythrocyte, and studies employing conformation-specific antibodies (anti-GLUT1-DTT antibodies, ∂-IgGs), indicate that erythrocyte-re

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17

Rahaghi, Farbod N. "Human blood glucose dynamics." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3259621.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed June 21, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 269-276).

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18

Roberts, Justin D. "Post exercise glucose metabolism." Thesis, Brunel University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249789.

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19

Mills, R. J. "Glucose modelling and clamping." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530854.

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20

Michala, Anna-Lito. "Capillary glucose detection system." Thesis, University of Strathclyde, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502356.

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Glucose absorbs electromagnetic energy in the near infrared (NIR) spectrum at characteristic wavelengths. An NIR beam is transmitted and as it passes through a solution this absorbance causes detectable spectral changes. The amount of spectral absorbance can be correlated to the concentration of glucose in the solution. In this study we used NIR Spectroscopy and micro sensors and detectors in order to detect glucose in small volume samples with economic instrumentation. The goal was to accurately measure the concentration of glucose in a solution held in a glass capillary vessel.

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21

Hussain, Faeiza. "Fluorescence-based glucose sensing." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417288.

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22

Lee, Mei-Ching. "Glucose-sensitive holographic sensors." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612883.

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23

Steinberg, Matthew David. "An implantable glucose biosensor." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625092.

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24

Pan, Xiaohan. "A holographic glucose sensor." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611684.

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25

Nybacka, Louise. "FTIR spectroscopy of glucose." Thesis, Uppsala universitet, Fasta tillståndets elektronik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-306952.

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Approximately 450 000 people have diabetes in Sweden today, and the number of diabetics only rises. Monitoring blood sugar several times a day is a fundamental part of managing the disease, and reducing the risks of complications. Today’s glucose monitoring devices are invasive and require small needle sticks for a measurement. Providing a painless method of monitoring the blood sugar level would relieve the lives of diabetics world-wide. The objective of this project was to investigate the absorption spectra of aqueous glucose concentrations (100 to 5000 mg/dl) in the mid infrared region wi

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26

Lloyd, Kenneth P. "Understanding Human Erythrocyte Glucose Transporter (GLUT1) Mediated Glucose Transport Phenomena Through Structural Analysis." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/962.

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GLUT1-mediated, facilitated sugar transport is proposed to be an example of transport by a carrier that alternately presents exofacial (e2) and endofacial (e1) substrate binding sites, commonly referred to as the alternating access carrier model. This hypothesis is incompatible with observations of co-existent exo- and endofacial ligand binding sites, transport allostery, and e1 ligand (e.g. cytochalasin B) induced GLUT1 sugar occlusion. The fixed-site carrier model proposes co-existent, interacting e2 and e1 ligand binding sites but involves sugar translocation by geminate exchange through in

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27

Khayat, Zayna A. "Multiple mechanisms of regulating glucose transporters and glucose transport in skeletal muscle cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ63589.pdf.

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28

Ling, Zong-Chao. "Islet glucose metabolism and insulin release in two animal models of glucose intolerance /." Stockholm, 1999. http://diss.kib.ki.se/1999/19990517ling/.

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29

Shipley, Timothy I. "The Role of VMN Glucose-Sensitive Neurones in the Control of Glucose Homeostasis." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511846.

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30

Osundiji, Mayowa Azeez. "Hypothalamic glucose sensing plays a critical role in the control of glucose homeostasis." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612423.

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31

Olver, Amy Virginia. "A characterization of glucose-induced downregulation of the glucose dependent insulinotropic polypeptide receptor (GIPR)." Thesis, University of British Columbia, 2006. http://hdl.handle.net/2429/32232.

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The primary role of the incretin hormone, glucose-dependent insulinotropic polypeptide (GIP) is to potentiate the secretion of insulin in a glucose-dependent manner. In humans and rat models with type 2 diabetes, however, this action is impaired as a result of attenuated GIP receptor (GIPR) expression in the pancreatic β-cell. It has been previously reported that glucose strongly downregulates GIPR mRNA expression in rat insulinoma FNS-1 (832/13) cells and rat islets in a concentration-dependent manner. Since chronic hyperglycemia was proposed to be a primary cause for GIP resistance one

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32

Whetstone, Heather Catherine. "Role of quinoprotein glucose dehydrogenase in metabolism of glucose and gluconate in Agrobacterium tumefaciens." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0011/MQ31475.pdf.

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33

McGarry, Robert Gerard. "Modelling insulin/glucose dynamics and application to the analysis of oral glucose tolerance tests." Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335562.

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34

Coudert, Edouard. "Mécanismes régulant l'utilisation périphérique du glucose chez l'oiseau : focus sur le transport de glucose." Thesis, Tours, 2016. http://www.theses.fr/2016TOUR4004/document.

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Le métabolisme glucidique de l’oiseau est important pour maitriser la croissance de l’animal et la qualité de la viande. Nous avons étudié l’utilisation périphérique du glucose chez le poulet au niveau musculaire en identifiant et en caractérisant les principaux acteurs impliqués. Nous avons identifié et caractérisé un nouveau transporteur de glucose chez les oiseaux, GLUT12. Il est exprimé dans les muscles, son expression est régulée in vivo par l’insuline et il peut être enrichi dans les membranes plasmiques des cellules suite à une stimulation insulinique. In vitro, une augmentation du tran

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35

Pears, John Stuart. "Glucose-6-phosphatase : its structure, function and regulation in relation to blood glucose homeostasis." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20100.

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Hepatic glucose-6-phosphatase (G6Pase) catalyses the final step in blood glucose production by the liver. It is a multicomponent system: the catalytic subunit is on the luminal surface of the endoplasmic reticulum membrane; there are transport proteins for glucose-6-phosphate, inorganic phosphate and glucose across the ER membrane; and there is a calcium-binding stabilising protein associated to the catalytic subunit. In fasted and diabetic humans (and rat models) kinetic analysis has shown that the capacity of the glucose-6-phosphate transport protein is the rate-limiting step in G6Pase activ

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36

Recchi, Carlo. "Selective photo-oxidation of glucose." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7650/.

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Biomass transformation into high-value chemicals has attracted attention according to the “green chemistry” principles. Low price and high availability make biomass one of the most interesting renewable resources as it provides the means to create sustainable alternatives to the oil-derived building blocks of the chemical industry In recent year, the need for alternative environmentally friendly routes to drive chemical reactions has in photocatalytic processes an interesting way to obtain valuable chemicals from various sources using the solar light as energy source. The purpose of this work

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37

Xuan, Wenxiang. "Glucose Levulinates as Bio-plasticizers." Thesis, KTH, Skolan för kemivetenskap (CHE), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-218153.

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Glucose, as the most plentiful sugar in nature, is a renewable resource and possesses excellent record in health safety. Levulinic acid is a platform chemical which plays an important role in biomass transformation and reactive intermediates. Both glucose and levulinic acid can be produced by biomass conversion with green processing techno logies. Due to the rising needs for bio-based, eco-friendly and non-toxic plasticizers, glucose levulinates as bio plasticizers were synthesized from glucose and levulinic acid, by utilizing microwave radiation or conventional condensation reaction (direc

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38

Dobson, Lee. "Glucose tolerance in cystic fibrosis." Thesis, University of Exeter, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403679.

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39

Foster, Leonard James. "Insulin-responsive glucose transporter traffic." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ63586.pdf.

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40

Thiên. "Glucose metabolism in falciparum Malaria." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/74040.

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41

Williams, Benedick John Lassetter. "ENDOR spectroscopy of glucose oxidase." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404900.

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42

Fragkou, Vasiliki. "Improvements in electrochemical glucose biosensors." Thesis, Cranfield University, 2010. http://dspace.lib.cranfield.ac.uk/handle/1826/6532.

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Diabetes is one of the leading causes of death and disability in the world. Even though insulin was discovered in 1920, an intense research on diabetes has been conducted during the last five decades and this is because of the market size. The huge demand is creating the need for the development of new approaches. This project involved the research aimed at better understanding and improvements in performance of glucose biosensors. In general, high surface area electrodes are desired as the high surface area provides more active sites for electrochemical reactions, and hence higher kinetic rat

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43

Eagles, O. D. "Non-invasive blood glucose monitoring." Thesis, Swansea University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636758.

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This Thesis covers the investigation into the feasibility of monitoring blood glucose non-invasively. The work carried out involved the development of an <I>in-vitro</I> instrument through a series of four stages, each stage of development being an improvement on the previous one. Using these instruments it was shown that by using an appropriate wavelength, glucose could be detected down to 156 mg/dL repeatedly in distilled water, saline and a non-opaque blood analogue. It was also demonstrated that this wavelength could be used to detect the difference between blood samples with different glu

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44

Troupe, Claire Elizabeth. "Glucose sensors utilising CVD diamond." Thesis, Heriot-Watt University, 1998. http://hdl.handle.net/10399/559.

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45

Morrow, David John. "Non-enzymatic electrochemical glucose detection." Thesis, Queen's University Belfast, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317087.

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46

Kumari, N. "Blood glucose levels and wellbeing." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374804.

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47

Morgan, Emma Louise. "Intestinal glucose and calcium absorption." Thesis, University of York, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424573.

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48

Williams, Andrew C. "Glucose metabolism in human spermatozoa." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302101.

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49

Parekh, Bhavin. "Volatile biomarkers of blood glucose." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609459.

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50

Kikuchi, Yoko. "Miniaturised glucose-oxygen biofuel cells." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/5868.

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Miniaturized glucose-oxygen biofuel cells are useful to power implantable medical devices such as biosensors. They are small, more biocompatible and run continuously on glucose and oxygen, providing cleaner energy at neutral environment. A typical glucose-oxygen biofuel cell consists of an anode with glucose oxidase (GOx) and a cathode with various oxygen reducing catalysts. This thesis describes experimental investigations of the major issues of such systems, viz.: complex electrode fabrication, enzyme instability and inefficient oxygen reduction. Electrodes were built using the simple and sc

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