Academic literature on the topic 'Glutamic acid polymers'

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Journal articles on the topic "Glutamic acid polymers"

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Thompson, Marisa, and Carmen Scholz. "Highly Branched Polymers Based on Poly(amino acid)s for Biomedical Application." Nanomaterials 11, no. 5 (2021): 1119. http://dx.doi.org/10.3390/nano11051119.

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Polymers consisting of amino acid building blocks continue to receive consideration for biomedical applications. Since poly(amino acid)s are built from natural amino acids, the same building blocks proteins are made of, they are biocompatible, biodegradable and their degradation products are metabolizable. Some amino acids display a unique asymmetrical AB2 structure, which facilitates their ability to form branched structures. This review compares the three forms of highly branched polymeric structures: structurally highly organized dendrimers, dendrigrafts and the less organized, but readily
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Sanda, Fumio, Taizo Fujiyama, and Takeshi Endo. "Chemical synthesis of poly-?-glutamic acid by polycondensation of ?-glutamic acid dimer: Synthesis and reaction of poly-?-glutamic acid methyl ester." Journal of Polymer Science Part A: Polymer Chemistry 39, no. 5 (2001): 732–41. http://dx.doi.org/10.1002/1099-0518(20010301)39:5<732::aid-pola1045>3.0.co;2-p.

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Baumgartner, Ryan, Diane Kuai, and Jianjun Cheng. "Synthesis of controlled, high-molecular weight poly(l-glutamic acid) brush polymers." Biomaterials Science 5, no. 9 (2017): 1836–44. http://dx.doi.org/10.1039/c7bm00339k.

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Gao, Baojiao, Liqin Zhang, and Dandan Zhang. "Effects of structures of bidentate Schiff base type bonded-ligands derived from benzaldehyde on the photoluminescence performance of polymer–rare earth complexes." Physical Chemistry Chemical Physics 20, no. 6 (2018): 4373–85. http://dx.doi.org/10.1039/c7cp07590a.

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Two kinds of bidentate Schiff base ligands derived from benzaldehyde, benzaldehyde/m-aminophenol (BAMA) type and benzaldehyde/glutamic acid (BAGL) type ligands, were synchronously synthesized and bonded on the backbone of polysulfone (PSF) through molecular design and by polymer reactions, and two functional polymers, PSF-BAMA and PSF-BAGL, were obtained.
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Tolmachev, Dmitry, George Mamistvalov, Natalia Lukasheva, Sergey Larin, and Mikko Karttunen. "Effects of Amino Acid Side-Chain Length and Chemical Structure on Anionic Polyglutamic and Polyaspartic Acid Cellulose-Based Polyelectrolyte Brushes." Polymers 13, no. 11 (2021): 1789. http://dx.doi.org/10.3390/polym13111789.

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We used atomistic molecular dynamics (MD) simulations to study polyelectrolyte brushes based on anionic α,L-glutamic acid and α,L-aspartic acid grafted on cellulose in the presence of divalent CaCl2 salt at different concentrations. The motivation is to search for ways to control properties such as sorption capacity and the structural response of the brush to multivalent salts. For this detailed understanding of the role of side-chain length, the chemical structure and their interplay are required. It was found that in the case of glutamic acid oligomers, the longer side chains facilitate attr
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Kino, Kuniki, Toshinobu Arai та Yasuhiro Arimura. "Poly-α-Glutamic Acid Synthesis Using a Novel Catalytic Activity of RimK fromEscherichia coliK-12". Applied and Environmental Microbiology 77, № 6 (2011): 2019–25. http://dx.doi.org/10.1128/aem.02043-10.

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ABSTRACTPoly-l-α-amino acids have various applications because of their biodegradable properties and biocompatibility. Microorganisms contain several enzymes that catalyze the polymerization ofl-amino acids in an ATP-dependent manner, but the products from these reactions contain amide linkages at the side residues of amino acids: e.g., poly-γ-glutamic acid, poly-ε-lysine, and cyanophycin. In this study, we found a novel catalytic activity of RimK, a ribosomal protein S6-modifying enzyme derived fromEscherichia coliK-12. This enzyme catalyzed poly-α-glutamic acid synthesis from unprotectedl-gl
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Cedrati, Valeria, Aurora Pacini, Andrea Nitti та ін. "“Clickable” bacterial poly(γ-glutamic acid)". Polymer Chemistry 11, № 35 (2020): 5582–89. http://dx.doi.org/10.1039/d0py00843e.

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Bonduelle, Colin, Fatma Makni, Laura Severac, et al. "Smart metallopoly(l-glutamic acid) polymers: reversible helix-to-coil transition at neutral pH." RSC Advances 6, no. 88 (2016): 84694–97. http://dx.doi.org/10.1039/c6ra19753a.

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Yuan, Weize, Remi Casier, and Jean Duhamel. "Unfolding of Helical Poly(L-Glutamic Acid) in N,N-Dimethylformamide Probed by Pyrene Excimer Fluorescence (PEF)." Polymers 13, no. 11 (2021): 1690. http://dx.doi.org/10.3390/polym13111690.

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The denaturation undergone by α–helical poly(L-glutamic acid) (PLGA) in N,N-dimethylformamide upon addition of guanidine hydrochloride (GdHCl) was characterized by comparing the fluorescence of a series of PLGA constructs randomly labeled with the dye pyrene (Py-PLGA) to that of a series of Py-PDLGA samples prepared from a racemic mixture of D,L-glutamic acid. The process of pyrene excimer formation (PEF) was taken advantage of to probe changes in the conformation of α–helical Py-PLGA. Fluorescence Blob Model (FBM) analysis of the fluorescence decays of the Py-PLGA and Py-PDLGA constructs yiel
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Nakahama, Masashi, Julien Reboul, Kenji Yoshida, Shuhei Furukawa, and Susumu Kitagawa. "l-Glutamic acid release from a series of aluminum-based isoreticular porous coordination polymers." Journal of Materials Chemistry B 3, no. 20 (2015): 4205–12. http://dx.doi.org/10.1039/c5tb00346f.

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Dissertations / Theses on the topic "Glutamic acid polymers"

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Adebayo, Olajumoke O. "Evaluation of bacterial polymers as protective agents for sensitive probiotic bacteria." Thesis, University of Wolverhampton, 2018. http://hdl.handle.net/2436/621096.

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Probiotics are live microorganisms which when administered in adequate amounts confer one or more health benefits on the host. Different processing conditions, the acidic condition of the stomach and exposure to hydrolytic enzymes affect the viability and efficacy of probiotic organisms. This study investigated the protective effects of two biopolymers poly-gamma-glutamic acid (γ-PGA) and bacterial cellulose (BC) on probiotics during freeze drying and during exposure to simulated intestinal juices and bile salts. The antibacterial property of Bifidobacterium strains was also investigated again
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Souza, Viviane Costa de. "Polímeros de ß-ciclodextrina : síntese, caracterização e utilização na obtenção/estabilização de nanopartículas de prata." Pós-Graduação em Química, 2017. https://ri.ufs.br/handle/riufs/6831.

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Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq<br>The development of polymers with the ability to transport and release drugs and bioactives has been growing rapidly because of their unique properties in protecting and enhancing solubilization of drugs in physiological media. In this work, polyesters derived from β-cyclodextrin were developed in two different systems: The former consisted of cyclodextrin cross-linked with citric acid and subsequently functionalized with glutamic acid. The latter was obtained from β-cyclodextrin esterified with gluthamic acid. T
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Prodhomme, Emmanuel Jean-Paul Fernand. "Poly #gamma#-D-glutamic acid as a template for functionalised water-soluble biomaterials." Thesis, University of Southampton, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396135.

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Bhat, Aditya. "Bacterial production of poly-γ-glutamic acid and evaluation of its effect on the viability of probiotic microorganisms". Thesis, University of Wolverhampton, 2012. http://hdl.handle.net/2436/241854.

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Poly-γ-glutamic acid (γ-PGA) is a naturally occurring biopolymer made up of repeating units of glutamic acid and can be potentially used for multiple applications. This study compared the production of γ-PGA by eight bacteria (B. subtilis 23856, B. subtilis 23857, B. subtilis 23858 B. subtilis 23859, B. subtilis natto, B. licheniformis 1525, B. licheniformis 6816 and B. licheniformis 9945a) in GS and E media. B. subtilis natto and B. licheniformis 9945a have been investigated extensively for γ-PGA production, however, the remaining six have not previously been used. Using the eight bacteria, y
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Čangelová, Katarína. "Studium možných aplikací polymeru kyseliny glutamové." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401873.

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The subject of the thesis is study of possible applications of isoform of glutamic acid polymer (-PGA). The theoretical part is focused on the properties of this biopolymer and potential applications in various areas. Producers and mechanisms of biosynthesis are also mentioned. In the experimental part, the polymer was firstly characterised by following methods: FT-IR spectroscopy, TGA, DSC and SEC-MALS. Its isoelectric point, antimicrobial activity and solubility in various solvents were also determined. The biopolymer was also precipitated by divalent cations and its interaction with opposi
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Alves, Maria José Ferreira. "Glutaminólise em astrocitomas." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-02122014-083743/.

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O metabolismo da glutamina (Gln) é alvo de atenções recentes para a compreensão da reprogramação metabólica para o suprimento energético das células tumorais em proliferação e para o desenvolvimento de novas estratégias terapêuticas em câncer. Tanto a absorção de glutamina quanto a taxa de glutaminólise, o catabolismo da Gln para gerar adenosina trifosfato (ATP) e lactato na mitocôndria estão aumentados em diferentes tumores. A Gln e glicose participam do processo da proliferação de células tumorais tanto na produção de (ATP) como no fornecimento de produtos intermediários utilizados na síntes
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Parkhe, Ajay Dattatraya. "Nanoscale scaffolding by folding of monodisperse and sequentially precise poly((alanine-glycine)(3)glutamic acid-glycine(glycine-alanine)(3)glutamic acid-glycine): Biosynthesis and characterization by X-ray diffraction, FTIR and NMR." 1994. https://scholarworks.umass.edu/dissertations/AAI9510516.

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We have designed repetitive polypeptides which would self assemble into a unique three dimensional structure. The de novo design of these polypeptides is based on existing information on protein chain folding. As a first step to designing more complicated scaffolds, we are interested in designing repetitive polypeptides which would self assemble into lamellae of uniform, predetermined thickness. The design of the polypeptide repeating unit has been based in part on work on the structure of silk (and its analogues) and in part on the literature on reverse turns in globular proteins. The polypep
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Zhang, Guanghui. "Poly(alpha,L-glutamic acid): Synthesis of its monodisperse derivatives and interaction of its alkylated derivatives with phospholipid bilayer membranes." 1994. https://scholarworks.umass.edu/dissertations/AAI9510553.

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A general strategy has been developed to synthesize biologically monodisperse polypeptides with the major repeat unit 1. These polymers are derivatives of poly($\alpha$,L-glutamic acid) (PLGA).$$- \rm Glu\sb{17}Asp-\qquad{\bf 1}$$ Such polymers should adopt an $\alpha$-helical structure when the side chain carboxylate groups are protonated, since Glu has the highest helix forming propensity (P$\sb\alpha$ = 1.59) of all twenty natural amino acids. Polymer 2 was synthesized as a fusion protein with glutathione S-transferase (GST) in a bacterial host, and was liberated from the GST fragment by CN
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Mohr, Benjamin Georg Robert. "Macromolecular assemblies: Human γ-crystallin protein, glutamic acid bottle brushes, and hyaluronic acid gels". 2013. https://scholarworks.umass.edu/dissertations/AAI3603124.

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Macromolecular assemblies constitute the world in which we live. The work contained within this thesis has studied three different types of macromolecular assemblies: human gamma-crystallin protein aggregation, the synthesis of glutamic acid bottle brushes, and cross-linked hyaluronic acid hydrogels. The in vitro study of human lens gamma-crystallin protein aggregation is the main component of this thesis. Separate projects that aid the body of this work include a description for the synthesis of glutamic acid bottle brush macromolecules and novel cross-linked networks of hyaluronic acid hydro
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王晢旭. "pH-responsive polymer vesicles assembled from lipid-contaning poly(γ-glutamic acid ) and their applications in drug delivery". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/88569342183263034880.

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碩士<br>國立清華大學<br>生醫工程與環境科學系<br>99<br>In this study, we used the biodegradable amphiphilic copolymers of lipid-modified poly(γ-glutamic acid) (Poly(γ-glutamic acid-co-distearin glutamate), γ-PGA-DSGA) prepared by modifying 1,2-distearoyl-rac-glycerol (distearin) as hydrophobic segments, onto poly(γ-glutamic acid) as the hydrophilic segments. The γ-PGA-based nanoparticles are prepared by self-assembly of amphiphilic copolymers in aqueous phase solution (pH 7.4 buffer). Combining the results of dynamic light scattering (DLS)、static light scattering (SLS) and transmission electron microscope (TEM),
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Book chapters on the topic "Glutamic acid polymers"

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Giannos, Steven A., Devang Shah, Richard A. Gross, David L. Kaplan, and Jean M. Mayer. "Poly(Glutamic Acid) Produced by Bacterial Fermentation." In Novel Biodegradable Microbial Polymers. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-2129-0_46.

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Giannos, Steven A., Devang Shah, Richard A. Gross, David Kaplan, and Jean M. Mayer. "The Biosynthesis of Unusual Polyamides Containing Glutamic Acid." In Biotechnology and Polymers. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3844-8_7.

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Xu, Zhinan, Huili Zhang, Hao Chen, et al. "Microbial Production of Poly-γ-Glutamic Acid." In Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118642047.ch23.

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Wohlfarth, Ch. "Second virial coefficient of poly(N-isopropylacrylamide-b-l-glutamic acid)." In Polymer Solutions. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-02890-8_580.

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Marsischky, G. T., M. Ikejima, H. Suzuki, et al. "Directed Mutagenesis of Glutamic Acid 988 of Poly(ADP-ribose) Polymerase." In ADP-Ribosylation Reactions. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4419-8718-1_6.

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Singer, Jack W., Brian Baker, Peter de Vries, et al. "Poly-(L)-Glutamic Acid-Paclitaxel (CT-2103) [XYOTAX™], a Biodegradable Polymeric Drug Conjugate." In Advances in Experimental Medicine and Biology. Springer US, 2004. http://dx.doi.org/10.1007/0-306-47932-x_6.

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Kunioka, Masao. "Biosynthesis of Poly(γ-glutamic acid) in Bacillus subtilis IFO3335 and Crosslinking Reaction by γ-Irradiation of Poly(γ-glutamic acid)." In Studies in Polymer Science. Elsevier, 1994. http://dx.doi.org/10.1016/b978-0-444-81708-2.50046-4.

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Conference papers on the topic "Glutamic acid polymers"

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Yang, Ge, Li-Qun Ma та Xue-Yan Su. "Improvement on Polymer Blending with Nano-Technology: selfassembled Poly(γ-glutamic acid)/chitosan (γ-PGA/CH)/blends". У 2016 International Conference on Advanced Materials, Technology and Application (AMTA2016). WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789813200470_0034.

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Henschen, A., та E. Müller. "ON THE FACTOR XIIIa-INDUCED CROSSLINKING OF HUMAN FIBRIN α-CHAINS". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644649.

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Factor XIIIa catalysis the formation of isopeptide bonds Between γ-carbamoyl groups of peptide-bound glutamines and ε-amino groups of lysines or lysine analogues. During fibrin crosslinking two such bonds are rapidly formed between the C-termini of two γ-chains in adjacent molecules and then several bonds are more slowly formed between several α-chains. The crosslinking sites in the γ-chain were identified already 15 years ago, those in the α-chain are still only tentatively or partially identified,, However, by determining the incorporation of lysine analogues in the α-chain it could be shown
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