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Relevant bibliographies by topics / Glycan derivatives

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Dissertations / Theses

Academic literature on the topic 'Glycan derivatives'

Author: Grafiati

Published: 14 March 2023

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Dissertations / Theses on the topic "Glycan derivatives"

1

Williams, Matthew. "The development of S-glycosylcysteine derivatives for use in glycan-binding assays." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/25655.

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This dissertation concerns the development of a synthetic route towards novel cysteine-based glycan-binding probes, for incorporation into glycoarrays and or similar applications used in assays of glycan-recognition phenomena. The need to systematically characterize the glycome and decipher the range of glycosylation patterns found in living cells, has prompted the development of molecular tools such as glycoarrays and related systems for immobilizing defined carbohydrate structures. The preparation of these probes requires access to building blocks where the core structure has defined glycans

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2

Garg, Monika [Verfasser]. "Conformational Analysis and Application in Diagnostic of Glycosylphosphatidylinositol Glycan Derivatives / Monika Garg." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1155761057/34.

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3

Puliti, Elisa. "Role of sphingosine 1-phosphate metabolism and signalling in skeletal muscle atrophy and fibrosis." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1195603.

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In the last 30 years, multiple roles of S1P have been demonstrated in the regulation of skeletal muscle biology. The presented study is focused on the role of S1P metabolism in myogenic differentiation, where SPL was found playing a crucial role in regulating S1P cellular levels and responsible for onset of myogenic program. The role of S1P axis was also confirmed in skeletal muscle atrophy induced by TNF-alpha. S1P signalling pathwayplays a crucial role in the development and maintenance of the fibrotic process. New S1P3 antagonists were tested to antagonise the receptor involved in fibrosis,

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4

Gruškienė, Rūta. "Cationized and poly(ethylene glycol) modified chitosan derivatives and nanoparticles." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2010. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100702_105158-57314.

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The main aim of this work was to synthesize water-soluble chitosan – methoxy poly(ethylene glycol) (MPEG) graft copolymers and cationized chitosan derivatives of various structure and desirable graft density, and to study their properties. Novel chitosan-MPEG derivatives with different degree of substitution of chitosan were prepared for the first time by “click” chemistry. Several new schemes of the synthesis of chitosan-MPEG and additionally cationized chitosan derivatives were suggested based on protection of amino functionality by using chitosan-dodecyl sulphate complexes. Additional catio

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5

Peters, Scott O. "Induced pi-facial discrimination in the alkylation of chiral derivatives of glycine." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0014/MQ52745.pdf.

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6

Idziak, Irene. "Synthesis of amide-backbone DNA analogues and their poly(ethylene glycol) derivatives." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40145.

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Thymidine dimers 16 and 18, connected by amide or N-methylamide linkages, have been prepared. The dimers were incorporated into normal strands of DNA by solid phase synthesis. Thermal denaturation studies, using complementary single-stranded RNA, indicated that these modifications caused no destabilization of the DNA-RNA duplex.<br>The block synthesis of amide-linked homotetramer 30 is described. The synthesis of the corresponding octamer could not be verified because of lack of solubility. One by one homologation was found to be a suitable method for the preparation of N-methylamide analogues

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7

Carter, James. "A New Synthetic Pathway Towards Legionaminic Acid." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/381511.

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This thesis describes the results of a PhD project aimed at researching a new synthetic pathway towards legionaminic acid analogues. Legionaminic acid is a bacterial family of nonulosonic acids expressed in a terminal position on the flagellar glycans and are considered to be a virulence factor in the pathogenic bacteria that possess them. At the outset of this project several examples of Leg synthesis had been published. Whilst three syntheses of Leg derivatives have been published while the research described in this thesis was being carried out, the potential of all the published syntheses

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8

Bright, Andrew G. "Mechanistic Insights into the Stabilisation of Biopharmaceuticals using Glycine Derivatives. The Effect of Glycine Derivatives on the Crystallisation, Physical Properties and Behaviour of Commonly used Excipients to Stabilise Antigens, Adjuvants and Proteins in the Solid State." Thesis, University of Bradford, 2015. http://hdl.handle.net/10454/15943.

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This dissertation has focused on studying the effect of four glycine derivatives on the solid state properties of mannitol, glycine, and sucrose when freeze dried into blended mixtures. The primary goal was to assess their value for use in the stabilisation of vaccines in the solid state, by examining key physical and chemical characteristics, which have been documented to be beneficial to the stabilisation of biopharmaceutical formulations. The novel excipients; dimethyl glycine, and trimethyl glycine, were shown to retard the crystallisation and increase the overall glass transition temperat

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9

Huo, Hongguang. "Tailored cell attachment and cytotoxicity in PEG-based polysaccharide-derivatized hydrogels." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 117 p, 2007. http://proquest.umi.com/pqdlink?did=1253510481&Fmt=7&clientId=79356&RQT=309&VName=PQD.

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10

Bagga, Kishore Kumar. "Synthesis of hexamethylmelamine, polyethylene glycol and glucose derivatives for use in anti-cancer and sugar transport studies." Thesis, Aberystwyth University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301609.

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