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1

Dreval', A. V., B. P. Kovachev, I. V. Misnikova, Yu A. Kovaleva, and O. A. Dreval'. "Study of new capacities in the evaluation of glycemic control in patients with type 2 diabetes." Problems of Endocrinology 55, no. 2 (2009): 35–40. http://dx.doi.org/10.14341/probl200955235-40.

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The purpose of the study was to comprehensively analyze glycemic control in type 2 diabetes (T2D) patients who were first given glucose-reducing therapy. Glidiab MB and Diabeton MB caused a comparable reduction in glycemic control parameters: the level of HbA1c, fasting glycemia, and mean glycemic levels as shown by the results of its continuous glucose monitoring system (CGMS) study. The lower glycemic level was not accompanied by weight gain and it improved lipid spectrum parameters. The readings of monthly self-control of glycemia were transformed to its deviation from the goal range (ADRR)
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2

Samoylova, Yu G., M. V. Matveeva, N. G. Zhukova, and M. A. Rokank. "Variability of glycemia and cognitive impairment in patients with diabetes mellitus type 1." Clinical Medicine (Russian Journal) 96, no. 8 (2018): 741–45. http://dx.doi.org/10.18821/0023-2149-2018-96-8-741-745.

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Diabetes mellitus type 1 is associated with impaired cognitive function. Based on the results of systematic reviews and meta-analyzes, the most likely modifiable risk factor is the degree of metabolic control, in particular the variability of glycemia. Aims: to determine the influence of the variability of glycemia on cognitive functions in patients with type 1 diabetes mellitus. Material and methods. Design-observational, one-stage, cross-sectional research. We examined 30 patients with type 1 diabetes mellitus who were divided into 2 groups: 1 group (main) with cognitive impairment, and 2 (c
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3

POZDNYAK, A. O., O. S. ELSUKOVA, and E. A. NIKITINA. "Glycemic control parameters in patients with type 2 diabetes mellitus under the fixed combination of insulin glargine and lixisenatide." Practical medicine 22, no. 6 (2024): 114–17. https://doi.org/10.32000/2072-1757-2024-6-114-117.

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The purpose was to investigate the dynamics of glycemic control parameters in patients with type 2 diabetes mellitus (T2DM) under the fixed combination (FC) of insulin glargine and lixisenatide over 24 months of observation. Material and methods. The study included 35 patients with T2DM who had not achieved target glycemic control parameters during previous hypoglycemic therapy. Anthropometric data, glycated hemoglobin (HbA1c), fasting glycemia, postprandial glycemia were assessed upon admission and 24 months after using the FC of insulin glargine and lixisenatide. Additionally, the frequency
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4

Liu, Chengfang, Yuqiao Zhang, Xiaohui Li, et al. "A Glycemia-Based Nomogram for Predicting Outcome in Stroke Patients after Endovascular Treatment." Brain Sciences 12, no. 11 (2022): 1576. http://dx.doi.org/10.3390/brainsci12111576.

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Objective: Higher fasting glucose is thought to be associated with adverse outcome in patients receiving endovascular treatment (EVT), while the effect of glycosylated hemoglobin (HbA1c) on outcome is controversial. We combined fasting blood glucose (FBG) with HbA1c and evaluated their relationship with the three-month functional outcome in patients who underwent EVT. Methods: Data from 739 consecutive ischemic stroke patients who underwent EVT from April 2015 to August 2021 were retrospectively reviewed. HbA1c was used to estimate the chronic glucose level according to the following formula:
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5

Chernikova, N. A., L. L. Kamynina та A. S. Ametov. "The сardiometabolic assessment of the glycemic variability in patients with diabetes mellitus: the role of the glucocardiomonitoring". Kardiologiia 60, № 5 (2020): 100–106. http://dx.doi.org/10.18087/cardio.2020.5.n902.

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Aim To study quantitatively the two-way relationship between parameters of glycemic variability and development of cardiovascular events in patients with type 2 diabetes mellitus (DM) on chronic sulfonylurea (SM) therapy by synchronous, professional glucose and cardiac monitoring.Material and methods The study included 421 patients with type 2 DM on SM therapy. A 5-day synchronous glucose and cardiac monitoring was performed for these patients in a retrospective mode using an iPro2 (Medtronic, USA) continuous glycemia monitoring (CGM) system and Holter monitoring. Glycemic endpoints (CGM-param
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Romantsova, Tatiana Ivanovna, and Irina Vladimirovna Glinkina. "Control of type 2 diabetes mellitus: problems and prospects for their solution." Diabetes mellitus 12, no. 4 (2009): 42–46. http://dx.doi.org/10.14341/2072-0351-5703.

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Important medico-social and economic implications of type 2 diabetes mellitus (DM2) are determined by its continuously growing prevalence, frequencyand severity of complications related to inadequate glycemic control. Large-scale studies (UKPDS, VADT, ACCORD, ADVANCE) havedemonstrated controversial effect of intensive glycemic control (estimated from HbA1c dynamics) on diabetic macrovascular complication. At thesame time, epidemiological, experimental, and observational studies yielded conclusive evidence of postprandial glycemia (PPG) contribution tooverall glycemic control and its role in th
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Alimova, I. L., and A. N. Demyanenko. "FUNCTIONAL CONDITION OF THE CARDIOVASCULAR SYSTEM IN CHILDREN WITH TYPE 1 DIABETES DEPENDING ON THE LEVEL OF GLYCEMIA." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 63, no. 5 (2018): 69–74. http://dx.doi.org/10.21508/1027-4065-2018-63-5-69-74.

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Purpose of the study: to determine main parameters of the heart rhythm in children with type 1 diabetes, depending on the night level of glycemia. We performed bifunctional monitoring of glycemia and ECG in 50 patients with type 1 diabetes from 10 to 17 years. Depending on the glycemic parameters summarized in all patients we divided 3 groups: Group 1 (n=11) – sites of hypoglycemia (≤3.9 mmol/l), Group 2 (n=35) – optimal level of glycemia (4.0-9.0 mmol/l) and Group 3 (n=45) – sites of hyperglycemia (> 9 mmol/l). According to the results of glycemic monitoring, 96% of children do not have gl
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8

Halushko, O. A., and M. V. Boliuk. "Characteristics of carbohydrate metabolism indicators in diabetic patients with acute coronary syndrome." Diabetes Obesity Metabolic Syndrome, no. 3 (June 28, 2024): 27–33. http://dx.doi.org/10.57105/2415-7252-2024-3-01.

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Studies show that all patients with uncontrolled glucose levels are at increased risk of complications during hospitalization. It has been proven that there is a relationship between the level of hyperglycemia and in-hospital mortality in patients admitted with myocardial infarction (MI). Aim. To study the features of carbohydrate metabolism indicators in diabetic patients with acute coronary syndrome. Materials and methods. The study included 48 patients (38 men and 10 women) aged 45-83 years, urgently hospitalized for acute coronary syndrome (ACS). Blood samples were collected from all patie
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Zykov, V. A., I. B. Krylova, T. P. Tuchina, and M. M. Galagudza. "Comparative study of the hypoglycemic and cardioprotective effects of glucagon-like peptide-1 receptors agonist exenatide, insulin and their combined use in myocardial ischemia/reperfusion injury in rats with experimental type 2 diabetes." Regional blood circulation and microcirculation 22, no. 2 (2023): 51–57. http://dx.doi.org/10.24884/1682-6655-2023-22-2-51-57.

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Introduction. Insulin therapy used during acute myocardial infarction (AMI) is associated with a high risk of hypoglycemia and high glycemic variability. Therefore, the search for optimal therapeutic approaches which affect both cardioprotection and glycemic correction is relevant. It is known that agonists of glucagon-like peptide-1 (aGLP1) exhibit a protective effect on the myocardium and are involved in the normalization of carbohydrate metabolism. The combined use of аGLP1 exenatide and insulin can be more effective and safe but not insufficiently studied.The aim of this study was the comp
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Lasisi, Ismaila A., Kamoru A. Adedokun, Musiliu A. Oyenike, Musa A. Muhibi, Ramat T. Kamorudeen, and Waheed A. Oluogun. "Glycemic control and its impact on oxidative stress biomarkers in type 2 diabetic patients treated with metformin: a cross-sectional analysis." Scientia Medica 29, no. 2 (2019): 33630. http://dx.doi.org/10.15448/1980-6108.2019.2.33630.

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AIMS: Evidence shows that diabetic patients may be predisposed to oxidative stress owing to increased glyco-oxidation and lipid peroxidation processes in consequence of chronic hyperglycemia. However, there is dearth of information whether glycemic control positively affects the antioxidant defense system in type 2 diabetes mellitus (T2DM). We investigated the potential association between glycemic control and oxidative stress biomarkers in controlled and uncontrolled diabetic states. METHODS: After obtaining ethical clearance, we included patients receiving metformin with glycated hemoglobin
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Kuznetsova, E. G., O. M. Kuryleva, L. A. Salomatina, G. N. Skaletskaya, N. N. Skaletskiy, and V. I. Sevastianov. "Specific efficiency of microemulsion matrix transdermal delivery system of insulin (experimental model of diabetes mellitus typeI)." Russian Journal of Transplantology and Artificial Organs 19, no. 3 (2017): 40–45. http://dx.doi.org/10.15825/1995-1191-2017-3-40-45.

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Aim. To study the specific activity of the microemulsion form of the matrix insulin transdermal delivery system in vivo on the experimental streptozotocin model of type I diabetes.Materials and methods.Male rats (n = 25) were randomized to the experimental and control groups. TDS insulin with a microemulsion composition was applicated to the animals of the experimental group (n = 15) for 4 days with daily replacement of TDS and control of the glycemia level. The glycemia level of the control group rats (n = 10) was determined throughout the experiment. The blood glucose concentration was measu
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12

Pertseva, N. O., and K. I. Moshenets. "Definition of the dependence of QTc interval prolongation on glycemic control in patients with type 2 diabetes mellitus." Medicni perspektivi 27, no. 1 (2022): 58–64. http://dx.doi.org/10.26641/2307-0404.2022.1.254326.

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The aim of the study: to assess the impact of glycemic variability on the duration of QTc interval in patients with diabetes mellitus type 2. 68 patients with type 2 diabetes mellitus (DM) and glycosylated hemoglobin (HbA1c) level ≤10% were examined. Of them – 37 (54.4%) men and 31 (45.6%) women. The average age – 46.0 (43.0; 54.0) years, the duration of DM type 2 – 7.0 (5.0; 9.0) years. Patients were divided into 2 groups according to HbA1c level: group 1 (n=31) with HbA1c <7% and group 2 (n=37) with HbA1c ≥7%. The control group consisted of 10 practically healthy people, compared by gende
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13

Basov, Igor, and Donatas Švitra. "Glycemia monitoring." Nonlinear Analysis: Modelling and Control 2 (December 21, 1998): 23–30. http://dx.doi.org/10.15388/na.1998.2.0.15282.

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Here a system of two non-linear difference-differential equations, which is mathematical model of self-regulation of the sugar level in blood, is investigated. The analysis carried out by qualitative and numerical methods allows us to conclude that the mathematical model explains the functioning of the physiological system "insulin-blood sugar" in both normal and pathological cases, i.e. diabetes mellitus and hyperinsulinism.
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Sopjani, Idriz, and Shpend Elezi. "Prevalence of hypertension and diabetes in the population of Kosovo." Frontiers of Nursing 8, no. 3 (2021): 261–67. http://dx.doi.org/10.2478/fon-2021-0027.

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Abstract Objectives To observe the prevalence of arterial pressure and glycemia in Kosovo and to provide free screening service through health promotion. Methods This prospective study was conducted over a 3-year period, during 2017–2019. All data were collected by AAB College staff in 11 Kosovo cities prior to a random sample with 7254 observations. Data included demographic information as well as blood pressure and glycemic level measurements. Results The overall prevalence of arterial pressure was registered at 27.6% and diabetes mellitus at 9.2%. Arterial pressure in females had a tendency
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15

Pertseva, N.O., and K.I. Moshenets. "Definition of the dependence of QTc interval prolongation on glycemic control in patients with type 2 diabetes mellitus." Medicni perspektivi 27, no. 1 (2022): 58–64. https://doi.org/10.26641/2307-0404.2022.1.254326.

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The aim of the study: to assess the impact of glycemic variability on the duration of QTc interval in patients with diabetes mellitus type 2. 68 patients with type 2 diabetes mellitus (DM) and glycosylated hemoglobin (HbA1c) level ≤10% were examined. Of them – 37 (54.4%) men and 31 (45.6%) women. The average age – 46.0 (43.0; 54.0) years, the duration of DM type 2 – 7.0 (5.0; 9.0) years. Patients were divided into 2 groups according to HbA1c level: group 1 (n=31) with HbA1c <7% and group 2 (n=37) with HbA1c ≥7%. The control group consisted of 10 practically heal
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16

Sharafetdinov, Kh Kh, V. A. Mescheryakova, O. A. Plotnikova, and О. I. Chernyak. "Effects of different sources of protein on the level of postalimentary glycemia in patients with type II diabetes mellitus." Problems of Endocrinology 41, no. 2 (1995): 14–17. http://dx.doi.org/10.14341/probl11363.

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Effects of different sources of protein on the level of postalimentary glycemia in type II diabetes mellitus were studied in 92 patients aged 35 to 56 (mean age 44.2 ± 5.0) with disease duration of 3 to 10 years (mean duration 5.2 ± 0.4 years). Six mixed breakfasts including various sources of plant and animal fat were tested. Each of these breakfasts contained 50 g of easily available carbohydrates; protein content varied from 8 to 40 g. The sources of plant protein were glutene concentrate and soybean protein isolate, milk (casecite) and fish (squid chops) were sources of animal protein. Add
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17

Kononenko, I. V., and O. M. Smirnova. "The importance of combined glycemic control in patients with type 2 diabetes mellitus." Problems of Endocrinology 56, no. 5 (2010): 43–51. http://dx.doi.org/10.14341/probl201056543-51.

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The contribution of intensive control of glycemia to the reduction of the risk of microvascular complications of type 2 diabetes mellitus is known perfectly well whereas its influence on the development of macrovascular complications remains to be clarified and remains a subject of debates. Bearing in mind that hyperglycemia is a key pathogenetic factor triggering formation of diabetic complications, it is necessary to identify characteristics of carbohydrate metabolism to be taken into account when choosing therapeutic strategies and to determine their target values. Control of the HbA1c leve
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18

Turchyna, S. I., L. D. Nikitina, S. O. Chumak, et al. "Features of glycemical control in modern adolescents with diabetes type 1 and influence of the war in ukraine on their condition." Ukrainian Journal of Pediatric Endocrinology, no. 2-3 (September 27, 2024): 11–18. http://dx.doi.org/10.30978/ujpe2024-2-3-11.

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Objective — to determine the state of glycemic control in adolescents with type 1 diabetes (T1D) in modern conditions and the impact of the war in Ukraine on its indicators. Materials and methods. A comprehensive examination of adolescents with type 1 diabetes aged 11—18 years, who were examined and treated in the endocrinological department of the SI «Institute for Children and Adolescents Health Care of the National Academy of Medical Sciences of Ukraine» during 2020—2024, was conducted. Clinical and anamnestic and laboratory­instrumental examination of patients was carried out in accordance
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19

Peterkova, Valentina A., Andrey O. Emelyanov, Dmitry N. Laptev, et al. "The efficacy of outpatient monitoring of children and adolescents with type 1 diabetes with regular use of professional continuous glucose monitoring." Problems of Endocrinology 66, no. 1 (2020): 14–22. http://dx.doi.org/10.14341/probl12200.

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BACKGROUND: According to research, only 38% of patients reach glycated hemoglobin targets. It is possible to improve the effectiveness of medical care for children with T1D using modern technologies, including continuous glucose monitoring (CGM).
 AIMS: To evaluate the effectiveness of outpatient monitoring of children and adolescents with T1D with regular use of professional continuous glucose monitoring.
 METHODS: The inclusion criteria: age 812 years; T1D at least 1 year; insulin therapy by multiple injections of insulin; inadequate glycemic control of T1D: НbА1с level of 7.5% and
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Samoilova, Yu G., M. V. Matveeva, O. S. Tonkikh, and N. Yu Fimushkina. "Brain perfusion in type 1 diabetes and cognitive dysfunction." Medical Visualization 25, no. 3 (2021): 66–72. http://dx.doi.org/10.24835/1607-0763-940.

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The purpose. To evaluate brain microcirculation using contrast and non-contrast magnetic resonance perfusion in patients with type 1 diabetes and cognitive dysfunction.Material and methods. The study complies with generally accepted ethical rules. The study included 45 patients with type 1 diabetes and cognitive dysfunction and 20 patients without. Every patient included in the study was continuously monitoring glycemia with evaluation of variability coefficients. MRI was performed using a magnetic resonance imaging scanner Signa Creator “E”, GE Healthcare, 1.5 Tl, China: methods – dynamic con
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Zhang, Xin-Miao, and Quan-Quan Shen. "Application and management of continuous glucose monitoring in diabetic kidney disease." World Journal of Diabetes 15, no. 4 (2024): 591–97. http://dx.doi.org/10.4239/wjd.v15.i4.591.

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Diabetic kidney disease (DKD) is a common complication of diabetes mellitus that contributes to the risk of end-stage kidney disease (ESKD). Wide glycemic var-iations, such as hypoglycemia and hyperglycemia, are broadly found in diabetic patients with DKD and especially ESKD, as a result of impaired renal metabolism. It is essential to monitor glycemia for effective management of DKD. Hemoglobin A1c (HbA1c) has long been considered as the gold standard for monitoring glycemia for > 3 months. However, assessment of HbA1c has some bias as it is susceptible to factors such as anemia and liver
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22

Saeed, Ammarah ,., Zunera Jahanzeb, Uzma Batool, Samia Kauser, Mushtaq Muhammad, and Nasir Mahmood. "Relationship of Glycemic Control with Level of Blood Pressure amongst Type 2 Diabetic Patients." Pakistan Journal of Medical and Health Sciences 16, no. 7 (2022): 982–84. http://dx.doi.org/10.53350/pjmhs22167982.

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Introduction: Inadequate control of glycemia in type-II diabetic patients is an important community health issue and a risk factor for the progression of problems among diabetic patients. Hypertension is a common disease accompanying diabetes. Among patients with diabetes mellitus; high blood pressure is an important factor involved in poor glycemic control which has not been adequately assessed in Pakistan. Aim: The main goal was to evaluate the glycemic control status in type II diabetic patient depending on the basis of blood pressure levels. Place and Duration: In Medicine Department of Is
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23

Brunello, A., R. Kapoor, and M. Extermann. "Influence of hyperglycemia on toxicity in older patients receiving chemotherapy." Journal of Clinical Oncology 25, no. 18_suppl (2007): 19579. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.19579.

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19579 Background: Few data are available concerning how glycemic control can affect outcomes in cancer patients (pts) treated with chemotherapy (CHT), particularly with those regimens that are more likely to cause increases in glycemia. Methods: Charts of non-Hodgkin lymphoma (NHL) and prostate cancer (PC) pts treated at Moffitt Cancer Center from January 1999 to September 2006 were reviewed, and pts who received Cyclophosphamide, Doxorubicin, Vincristine, Prednisone and Rituximab or Docetaxel-based CHT plus steroids were eligible. Demographics, vitals, comorbidity, biochemicals including base
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Bjerager, Jakob, Sami Dabbah, Mohamed Belmouhand, et al. "Long-term development of lens fluorescence in a twin cohort: Heritability and effects of age and lifestyle." PLOS ONE 17, no. 5 (2022): e0268458. http://dx.doi.org/10.1371/journal.pone.0268458.

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The blue-green autofluorescence of the ocular lens increases with age, glycemia and smoking, as the irreplaceable structural proteins of the lens slowly accumulate damage from the encounter with reactive molecular species. We have conducted a prospective study of lens autofluorescence over two decades in a twin cohort. The study included 131 phakic, non-diabetic adult twins (median age at follow-up 58 years, range 41–66 years) who were examined twice at an interval of 21 years. Change in anterior lens peak autofluorescence was analyzed in relation to age, current and baseline glycemia, cumulat
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Misnikova, Inna, Yulia Kovaleva, Svetlana Shokur, Tyler W. LeBaron, Oxana Povarova, and Oleg Medvedev. "Hydrogen and Methane Detection in Breath in Response to Two Different Types of Dietary Fiber and Its Relationship to Postprandial Glucose Concentration in Obese Patients with Type 2 Diabetes and Normoglycemic Subjects." Nutrients 17, no. 5 (2025): 917. https://doi.org/10.3390/nu17050917.

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Background: The aim of this study was to investigate the relationship between postprandial glycemic levels based on flashmonitoring and the production of intestinal hydrogen (H2) and methane (CH4) gases based on the measurement of the amount of these gases in exhaled air. Materials and Methods: We studied 14 subjects with type 2 diabetes mellitus (T2DM) and 14 individuals without diabetes (control) with two food load tests, including two types of dietary fiber (inulin and guar gum), with the simultaneous determination of gases in exhaled air and the assessment of glucose levels. Results: All s
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Budylina, S. M., and A. L. Davydov. "Gustatory perception of children with diabetes mellitus." Problems of Endocrinology 40, no. 6 (1994): 15–17. http://dx.doi.org/10.14341/probl12183.

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Gustatory perception was studied in 10 children aged 8 to 15 suffering from medium-severe diabetes mellitus by the functional mobility method. Glycemia values and the level of mobilization of gustatory lingual papillae were high when the patients were admitted; the characteristic reverse proportinal relationship between these values, observed in healthy children, was absent. A course of therapy resulted in reduction of glycemia level, but the level of mobilization of gustatory papillae on an empty stomach was unchanged, the gastrolingual reflex did not recover. The detected dissociation betwee
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27

Mayorova, E. V., M. B. Lyasnikova, and G. Y. Vaal. "A clinical case of bilateral traction retinal detachment in a patient with type 2 diabetes mellitus." Reflection, no. 1 (September 20, 2023): 123–26. http://dx.doi.org/10.25276/2686-6986-2023-1-123-126.

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Aim. To analyze a clinical case of traction retinal detachment in both eyes in a patient with normal blood glucose levels. To determine additional diagnostic methods for verifying the diagnosis of diabetes mellitus in patients with normal levels of glucose and glycated hemoglobin with diabetic microvascular disorders. Methods. A patient with bilateral retinal traction detachment and without previous diagnosis of diabetes mellitus was observed. The patient had his blood glucose and glycated hemoglobin level within normal laboratory values. Results. A clinical case of a patient with retinal comp
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NERY-NETO, Jose A., Andrew O. SANTOS, Larissa C. SILVA, et al. "Glycemic control in diabetes mellitus in patients assisted by a university hospital in the state of Piauí (Brazil)." Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde 11, no. 4 (2020): 505. http://dx.doi.org/10.30968/rbfhss.2020.114.0505.

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Objectives: To investigate glycemic control in outpatient clinics at a university hospital, as well as to correlate HbA1c with fasting glucose and post-prandial glycemia, in order to assess which variable best correlates with an HbA1c. Methods: This is a descriptive cross-sectional study, with data that were collected from electronic medical records, from the random consultation of the medical of the blood glucose measurement. To check glycemic control, the parameters defined by the Brazilian Diabetes Society (2017-2018) were used: fasting glucose <100 mg / dL, HbA1c <7% and postprandial
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29

Langer, Oded, and Deborah L. Conway. "Level of glycemia and perinatal outcome in pregestational diabetes." Journal of Maternal-Fetal and Neonatal Medicine 9, no. 1 (2000): 35–41. http://dx.doi.org/10.3109/14767050009020510.

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Malvezzi, Maria Aparecida Pereira Nunes, Heloisa Aparecida Barbosa Silva Pereira, Aline Dionizio, et al. "Low-level fluoride exposure reduces glycemia in NOD mice." Ecotoxicology and Environmental Safety 168 (January 2019): 198–204. http://dx.doi.org/10.1016/j.ecoenv.2018.10.055.

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Langer, Oded, and Deborah L. Conway. "Level of glycemia and perinatal outcome in pregestational diabetes." Journal of Maternal-Fetal Medicine 9, no. 1 (2000): 35–41. http://dx.doi.org/10.1002/(sici)1520-6661(200001/02)9:1<35::aid-mfm8>3.0.co;2-6.

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32

Bessonov, I. S., V. A. Kuznetsov, I. P. Ziryanov, S. S. Sapozhnikov, and Yu V. Potolinskaya. "Impact of Diabetes Mellitus and blood glucose levels on the results of treatment of patients with ST-elevation myocardial infarction undergoing percutaneous coronary interventions." Kardiologiia 59, no. 3S (2019): 16–22. http://dx.doi.org/10.18087/cardio.2520.

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The aim of this study was to evaluate the impact of diabetes mellitus (DM) and glucose levels on the results of treatment of patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary interventions (PCIs). Materials and methods. Data were collected from all patients (n=1280) with STEMI who were admitted to the coronary care unit and underwent PCIs from 2006 to 2015. 212 (16.6%) patients with DM were compared with 1068 (83.4%) patients without DM (non-DM group). To investigate the influence of the blood glucose levels, all patients were divided into two groups abo
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Koshelskaya, O. A., N. V. Naryzhnaya, I. V. Kologrivova, et al. "The level of reactive oxygen species production by adipocytes of epicardial adipose tissue is associated with an increase in postprandial glycemia in patients with severe coronary atherosclerosis." Siberian Journal of Clinical and Experimental Medicine 36, no. 3 (2021): 59–67. http://dx.doi.org/10.29001/2073-8552-2021-36-3-59-67.

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The mechanisms of oxidative stress in adipocytes of local fat depots in patients with cardiometabolic diseases have been studied insufficiently.Purpose. To study the levels of reactive oxygen species (ROS) production in adipocytes of epicardial (EAT) and subcutaneous adipose tissue (SAT) in patients with stable coronary artery disease (CAD) and severe coronary atherosclerosis who underwent coronary artery bypass grafting; to investigate the potential relationships between the levels of ROS production by EAT and SAT adipocytes and obesity parameters, EAT accumulation, basal and postprandial gly
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34

Deynega (Masel), A. S., A. S. Liskina, S. A. Valieva, and I. L. Nikitina. "Assessment of the physical development and metabolic status of children born to women with gestational diabetes." Diabetes mellitus 24, no. 4 (2021): 325–33. http://dx.doi.org/10.14341/dm12463.

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Backgraund: Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders found during pregnancy. Currently, it is relevant not only to search optimal target levels of glycemia during pregnancy, but also to study the ­effect of different glycemia levels on fetal development and further changes in glucose and lipid metabolism in children.Aims: To describe perinatal period, physical development and metabolic status of children born to women with GDM and different glucose levels during pregnancy.Materials and methods: The perinatal period features and anthropometric parameters
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Myśliwiec, Artur, Maria Skalska, Arkadiusz Michalak, et al. "Responses to Low- and High-Intensity Exercise in Adolescents with Type 1 Diabetes in Relation to Their Level of VO2 Max." International Journal of Environmental Research and Public Health 18, no. 2 (2021): 692. http://dx.doi.org/10.3390/ijerph18020692.

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The purpose of this study was to investigate the influence of maximal oxygen uptake (VO2 max) on the glycemic changes during low and high intensity exercises in young type 1 diabetic patients. Twenty boys (age: 14.3 ± 1.6 years; height: 171.0 ± 11.3 cm; weight; 59.5 ± 12.8 kg) were divided into low-fit group (LFG, n = 10) and high-fit group (HFG, n = 10). According to the experimental design, participants performed three physical efforts (VO2 max test, mixed aerobic–anaerobic effort and aerobic effort) on the cycloergometer, during which real-time glycemia was measured. Mixed aerobic–anaerobic
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Lin, Cheng-Chieh, Chia-Ing Li, Chiu-Shong Liu, et al. "Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/841497.

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Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population.Methods. We did a cross-sectional survey in a representative sample of 2,350 Taiwanese adults aged 40 years and over living in a metropolitan city in Taiwan from 2004 to 2005. Glycemic status was classified as normal glycemia, hyperglycemia, and type 2 diabetes (T2D). Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease
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Bulgakova, S. V., O. V. Kosareva, Yu A. Dolgikh, L. A. Sharonova, and A. G. Mamedova. "The role of glycemic control in the development of late complications of diabetes mellitus." Meditsinskiy sovet = Medical Council, no. 23 (January 20, 2024): 228–33. http://dx.doi.org/10.21518/ms2023-461.

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The incidence of type 2 diabetes mellitus is constantly increasing throughout the world. It is known that type 2 diabetes is associated with the development of atherosclerotic cardiovascular diseases, chronic heart failure, and chronic kidney disease. Modern therapy for type 2 diabetes mellitus requires complex treatment and should be aimed not only at reducing glycemia, but also at managing the risks of cardiovascular and renal complications. The results of large scientific studies ADVANCE, ACCORD and VADT have clearly proven the role of glycemic control in the prevention of microvascular com
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Laptev, D. N., G. V. Riabykina, A. V. Sobolev, K. K. Kirillov, and A. A. Seid-Guseĭnov. "The relationship between the level of glycemia, the length of the QT-interval, and locomotor activity in children and adolescents presenting with type 1 diabetes mellitus." Problems of Endocrinology 56, no. 6 (2010): 24–31. http://dx.doi.org/10.14341/probl201056624-31.

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In this study, we investigated the relationship between the blood glucose level and the length of the QT-interval as well as the influence of locomotor activity on these characteristics in children and adolescents presenting with type 1 diabetes mellitus during the long-term monitoring of ECG, the level of glycemia, and locomotor activity. The daily dynamics of these parameters was elucidated along with the measurements of the lengths of QT and RR intervals. Specifically, the correlation between the length of the QTc interval and the blood glucose level appears from the fact that the maximum Q
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Christensen, Mikkel B., Asger Lund, Salvatore Calanna, et al. "Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia." Journal of Clinical Endocrinology & Metabolism 103, no. 1 (2017): 288–94. http://dx.doi.org/10.1210/jc.2017-01949.

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Abstract Context The gut hormone glucose-dependent insulinotropic polypeptide (GIP) causes postprandial insulin release and inhibits bone resorption assessed by carboxy-terminal collagen crosslinks (CTX). Objective To study if GIP affects bone homeostasis biomarkers independently of insulin release and glycemic level. Design Randomized, double-blinded, crossover study with 5 study days. Patients Ten male C-peptide-negative patients with type 1 diabetes. Interventions On 3 matched days with “low glycemia” (plasma glucose in the interval 3 to 7 mmol/L for 120 minutes), we administered intravenou
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Shabunin, A. V., A. S. Ametov, M. M. Tavobilov, et al. "Glycemia control after total pancreatoduodenectomy." Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery 29, no. 2 (2024): 90–98. http://dx.doi.org/10.16931/1995-5464.2024-2-90-98.

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Aim. To study the features of correction of carbohydrate metabolism disorders and nutritional deficiency in patients after total pancreatoduodenectomy; to develop a unified protocol for managing patients after total pancreatoduodenectomy. Materials and methods. From 2007 to 2022, 62 patients underwent total pancreatoduodenectomy in the Hepatopancreatic Surgery Unit of the Botkin Hospital. The patients were divided into two groups, comparable in terms of basic parameters. The first group included patients (n = 32) who underwent “classical” total pancreatoduodenectomy with gastric resection and
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Corrao, Salvatore, Alessandro Nobili, Giuseppe Natoli, et al. "Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry." Acta Diabetologica 58, no. 9 (2021): 1225–36. http://dx.doi.org/10.1007/s00592-021-01716-8.

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Abstract Aims The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. Methods Data were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). Patients were recruited during four index weeks of a year. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumula
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Samoilova, Iu G., M. V. Koshmeleva, O. A. Oleynik, E. I. Trifonova, D. A. Kachanov, and V. E. Mutalimi. "Self-monitoring with a home glucometer as a reliable method for controlling for diabetes mellitus type 1: pilot study." Meditsinskiy sovet = Medical Council, no. 1 (March 12, 2023): 82–88. http://dx.doi.org/10.21518/ms2023-038.

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Introduction. According to current clinical guidelines for the effective treatment of type 1 diabetes mellitus (DM1) in children and adolescents, regular self-monitoring of blood glucose using a glucose meter is an integral part of all training and long-term follow-up programs.Aim. To evaluate the clinical and metabolic efficiency of the method of self-monitoring of glycemia with a home glucometer in patients with diabetes DM1.Materials and methods. The study included 107 patients with DM1 using the method of self-monitoring of glycemia using a home glucometer. Based on the received reports wa
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Dreval, A. V., B. P. Kovachev, E. G. Starostina, I. V. Misnikova, and O. A. Dreval. "Analysis of a continuous 24-hour glycemic curve by the symmetrization method." Problems of Endocrinology 55, no. 1 (2009): 3–7. http://dx.doi.org/10.14341/probl20095513-7.

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The study included 18 patients (10 females and 8 males) with a not less than 2 year-history of type 1 diabetes (T1D), who had received insulin therapy since its diagnosis was established. The patients ’ mean age was 32.9± 13.0 years; the mean duration of TID was 15.1+11.5 years; the mean daily dose of insulin was 40.1+16.0 units; the mean level of glycosylated hemoglobin (HbAJ was 9.4±2.1% (the normal value 4.4-4.9%).&#x0D; The glycemic curve symmetrization method proposed for statistical analysis of glycemic self-control is also quite suitable for the statistical monitoring of a continuous da
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Mkrtumyan, Ashot Musaelovich. "The level of glycemia as a risk factor of cardiovascular diseases." Diabetes mellitus 13, no. 3 (2010): 80–82. http://dx.doi.org/10.14341/2072-0351-5493.

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The paper deals with the main aspects of pathogenesis of cardiovascular diseases in patients with disturbed carbohydrate metabolism. Results of theADVANCE study are presented that confirm the importance of intensive control of glycemia for the reduction of the overall risk of diabetic complicationsand death from cardiovascular pathology.
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Lobanova, K. G., A. S. Severina, S. A. Martinov, M. Sh Shamkhalova, and M. V. Shestakova. "Glycemic control in patients with diabetes mellitus on hemodialysis." Terapevticheskii arkhiv 91, no. 10 (2019): 124–34. http://dx.doi.org/10.26442/00403660.2019.10.000352.

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Achievement of stabilization of carbohydrate metabolism in patients with diabetes mellitus, receiving renal replacement therapy with hemodialysis, is a significant problem in endocrinology. It has to do with multiple factors of this cohort of patients, which affect the level of glycemia, pharmacokinetic of drugs, the efficiency of glycemic control. At the moment, the most efficiency method of glycemic control in patients with type 2 diabetes mellitus on hemodialysis is insulin therapy in the basis - bolus regime by analogues of human insulin. The use of oral hypoglycemic agents is significantl
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Ramírez Stieben, Luis Agustín, Raquel Dobry, Lilian Anca, et al. "Hypovitaminosis D in patients with type 2 diabetes." Revista de la Facultad de Ciencias Médicas de Córdoba 79, no. 3 (2022): 235–40. http://dx.doi.org/10.31053/1853.0605.v79.n3.35158.

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Introduction. Several studies reported than vitamin D deficiency increases the risk of macrovascular and microvascular disease in patients with type 2 diabetes (T2DM). We investigated the plasma levels of 25OHD in adult patients T2DM, risk factors for 25OHD deficiency and the relationship between 25OHD, glycemic control and chronic complications of T2DM. Methods. A cross-sectional study was carried out, in which 25OHD levels were evaluated in adult patients (over 18 years) with T2DM. Correlation analyses were performed to evaluate the interdependence of the 25OHD with other continuous variable
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Starostina, Ye G., G. R. Galstyan, and I. I. Dedov. "Current methods and means of metabolism automonitoring in diabetes mellitus." Problems of Endocrinology 40, no. 1 (1994): 36–39. http://dx.doi.org/10.14341/probl11295.

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Self-control (SC) in the broad sense of the word is the registration of trained patients with diabetes mellitus, subjective sensations, glycemia, glucosuria and other indicators, as well as diet and physical activity in order to make independent therapeutic decisions. It is more correct to use the term “self-control” in the narrow sense, only to indicate SC metabolism, that is, to independently determine the patient’s blood sugar or urine content, which will be the subject of this lecture. Using modern methods of rapid analysis, patients can independently evaluate the most important parameters
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Stantić-Romić, Dijana, Hajnalka Požar, and Sanja Šumonja. "Effect of Health educational intervention in the form of counseling on changes in anthropometric and biochemical parameters of type 2 diabetes mellitus." Sestrinska rec 26, no. 86 (2023): 17–23. http://dx.doi.org/10.5937/sestrec2386017s.

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Introduction: Diabetes is a significant public health problem. In Serbia, 12% of the population suffers dominantly from type 2 diabetes, the development of which is associated with an inadequate diet and lack of physical activity. The treatment of patients involves the application of diet therapy in combination with medical treatment. The aim of this paper is to evaluate the differences in anthropometric and biochemical parameters in patients with type 2 diabetes after the counseling work. Respondents and methods: The research was conducted as a retrospective evaluation study through the analy
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Kalinin, A. L., N. A. Strebkova, O. G. Zheludkova, M. A. Kareva, N. A. Mazerkina, and O. B. Bezlepkina. "Carbohydrate metabolism in children after complex treatment of medulloblastoma." Diabetes mellitus 24, no. 6 (2022): 529–35. http://dx.doi.org/10.14341/dm12805.

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BACKGROUND: Disorders of carbohydrate metabolism are frequent complications after complex treatment of cancer. Early detection of these disorders allows to modify lifestyle, if necessary, apply drug therapy and correct the identified changes in time, which will subsequently lead to a decrease in cardiovascular risks, an improvement in the quality and an increase in the life expectancy of this group of patients.AIM: To identify the frequency of occurrence and determine the optimal methods for early diagnosis of carbohydrate metabolism disorders in children after complex treatment of medulloblas
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Chernikova, N. A., L. L. Kamynina, A. S. Ametov, D. A. Sychev, E. A. Grishina, and K. A. Ryzhikova. "The pharmacogenetics of hypoglycemia and the glycemic variability at the patients ith type 2 diabetes mellitus." Terapevticheskii arkhiv 92, no. 10 (2020): 54–62. http://dx.doi.org/10.26442/00403660.2020.10.000530.

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Aim.To investigate the link between the hypoglycemia (registrated accurately by the professional Continuous Glucose Monitoring CGM; severe hypoglycemia at home) and the hetero-/homozygote carriage of single nucleotide polymorphisms (SNP) of cytochrome systems geneCYP2C9(rs1799853CYP2C9*2 иrs1057910CYP2C9*3) at the patients with Type 2 Diabetes Mellitus (T2DM) used sulphonylurea (SU).&#x0D; Materials and methods.In Study Case-Control 120 T2DM-SU-patients genotyped by SNPs of geneCYP2C9(using PCR-RT) had been done the professional CGM (System iPro2, Medtronic) recorded Time in Range of Hypoglyce
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