Academic literature on the topic 'Glycosides – therapeutic use'

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Journal articles on the topic "Glycosides – therapeutic use"

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Groult, Hugo, Isabel García-Álvarez, Lorenzo Romero-Ramírez, et al. "Micellar Iron Oxide Nanoparticles Coated with Anti-Tumor Glycosides." Nanomaterials 8, no. 8 (2018): 567. http://dx.doi.org/10.3390/nano8080567.

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The synthesis procedure of nanoparticles based on thermal degradation produces organic solvent dispersible iron oxide nanoparticles (OA-IONP) with oleic acid coating and unique physicochemical properties of the core. Some glycosides with hydrophilic sugar moieties bound to oleyl hydrophobic chains have antimitotic activity on cancer cells but reduced in vivo applications because of the intrinsic low solubility in physiological media, and are prone to enzymatic hydrolysis. In this manuscript, we have synthetized and characterized OA-IONP-based micelles encapsulated within amphiphilic bioactive
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Kochetov, Aleksey Aleksandrovich, and Nadezhda Georgiyevna Sinyavina. "STEVIA (STEVIA REBAUDIANA BERTONI): BIOCHEMICAL COMPOSITION, THERAPEUTIC PROPERTIES AND USE IN THE FOOD INDUSTRY (REVIEW)." chemistry of plant raw material, no. 2 (June 10, 2021): 5–27. http://dx.doi.org/10.14258/jcprm.2021027931.

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The review presents the current state of the science for stevia (Stevia rebaudiana Bertony), its biochemical composition, therapeutic properties and using in the food industry. Interest in this plant, a source of natural low-calorie sweeteners, is associated with increased consumption of dietary sweeteners, caused by an increase in the number of patients with diabetes, metabolic syndrome, and with many negative effects from the use of synthetic sweeteners. Diterpene glycosides from stevia have a high sweetness (50-350 times sweeter than sucrose), low calorie content, safe for human health. In
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Innocent Izuchukwu Ujah, Chukwunonso Anthony Nsude, Onuabuchi Nnenna Ani, Uchenna Blessing Alozieuwa, Innocent Oluwaseun Okpako, and Amos Ejiofor Okwor. "Phytochemicals of neem plant (Azadirachta indica) explains its use in traditional medicine and pest control." GSC Biological and Pharmaceutical Sciences 14, no. 2 (2021): 165–71. http://dx.doi.org/10.30574/gscbps.2021.14.2.0394.

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Neem Azadirachta indica is a useful traditional medicinal plant growing in Nigeria, India, and America. The phytochemicals and the biopesticidal components present were ascertained. The results showed that saponins, steroids and terpenes were mostly present, while tannins and glycosides were moderately present, and alkaloids, flavonoids, phenols and oxalic acid were least present. The presence of these phytochemical could account for the therapeutic uses of neem.
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Luwańska, Aleksandra, Aleksandra Perz, Grażyna Mańkowska, and Karolina Wielgus. "Application of in vitro stevia (Stevia rebaudiana Bertoni) cultures in obtaining steviol glycoside rich material." Herba Polonica 61, no. 1 (2015): 50–63. http://dx.doi.org/10.1515/hepo-2015-0010.

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Summary Stevia is a plant attracting attention due to its capability to synthesize a group of chemical compounds with sweet taste, i.e. steviol glycosides. Steviol glycosides are successfully applied as a natural sweetener, and some of them have also therapeutic properties. This paper presents available information on the use of stevia plant tissue cultures with the focus on their potential application in food industry. Detailed analysis was done concerning the research employing in vitro culture techniques and the use of them in biosynthesis of secondary metabolites of high importance for the
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Dauda Muhammed, Yetunde H. Adebiyi, Bernard O. Odey, et al. "Dennettia tripetala (Pepper Fruit), a review of its ethno-medicinal use, phyto-constituents, and biological properties." GSC Advanced Research and Reviews 6, no. 3 (2021): 035–43. http://dx.doi.org/10.30574/gscarr.2021.6.3.0024.

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There has been tremendous growth in field of herbal medicine as therapeutic agents. Dennettia tripetala, is known to possess ethnomedicinal properties and has been used for centuries in the Ayurvedic system of medicine for the treatments of various diseases. The present review provides detailed description on the distribution, ethno-medicinal use, phyto-constituents, and biological properties of the plant that justifies its use as a potential therapeutic agent in management of different diseases. The phyto chemical composition of Dennettia tripetala include alkaloids, tannins, saponins, flavon
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Baek, Su Cheol, Sang Ah Yi, Bum Soo Lee, et al. "Anti-Adipogenic Polyacetylene Glycosides from the Florets of Safflower (Carthamus tinctorius)." Biomedicines 9, no. 1 (2021): 91. http://dx.doi.org/10.3390/biomedicines9010091.

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Safflower (Carthamus tinctorius) is an annual herb belonging to the Compositae family; it has a history of use as a food colorant, dye, and medicine in oriental countries. LC-MS-UV-based chemical analysis of extract of the florets of C. tinctorius led to the isolation of two new C10-polyacetylene glycosides, (8Z)-decaene-4,6-diyne-1,10-diol-1-O-β-d-glucopyranoside (1) and (8S)-deca-4,6-diyne-1,8-diol-1-O-β-d-glucopyranoside (2), together with five known analogs (3–7). The structures of the new compounds were determined by using 1D and 2D NMR spectroscopic data and HR-MS data, as well as chemic
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Cole, Patricia L., and Thomas W. Smith. "Use of Digoxin-Specific Fab Fragments in the Treatment of Digitalis Intoxication." Drug Intelligence & Clinical Pharmacy 20, no. 4 (1986): 267–70. http://dx.doi.org/10.1177/106002808602000403.

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The narrow margin between therapeutic and toxic effects of digitalis glycosides renders patients taking these drugs particularly susceptible to serious consequences of accidental or deliberate overdosage, including life-threatening arrhythmias. Until recently, the treatment of digitalis intoxication has been largely supportive. In the past decade, however, digoxin-specific antibodies have been developed and have proven to be effective in rapidly reversing the electrophysiologic and metabolic manifestations of digitalis intoxication, both in vitro and in vivo. Enzymatic cleavage of the intact a
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Vemuri, R., S. Longoni, and K. D. Philipson. "Ouabain treatment of cardiac cells induces enhanced Na+-Ca2+ exchange activity." American Journal of Physiology-Cell Physiology 256, no. 6 (1989): C1273—C1276. http://dx.doi.org/10.1152/ajpcell.1989.256.6.c1273.

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Inhibition of the cardiac Na+-K+-ATPase with cardiac glycosides causes a rise in internal Na+ and a subsequent increase in cellular Ca2+ due to the sarcolemmal Na+-Ca2+ exchange mechanism. We investigated the adaptation of cultured cardiac cells to prolonged elevation of internal Ca2+ after exposure to ouabain. Cultured neonatal rat heart cells were treated with 100 microM ouabain for 4-48 h. This ouabain concentration inhibited Na+-K+-ATPase activity by approximately 45% and caused modest cellular Ca2+ loading. We found that cells adapted to ouabain treatment by increasing the amount of sarco
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Shi, Ze-Yu, Jin-Zhang Zeng, and Alice Sze Tsai Wong. "Chemical Structures and Pharmacological Profiles of Ginseng Saponins." Molecules 24, no. 13 (2019): 2443. http://dx.doi.org/10.3390/molecules24132443.

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Ginseng is a group of cosmopolitan plants with more than a dozen species belonging to the genus Panax in the family Araliaceae that has a long history of use in traditional Chinese medicine (TCM). Among the bioactive constituents extracted from ginseng, ginseng saponins are a group of natural steroid glycosides and triterpene saponins found exclusively throughout the plant. Studies have shown that these ginseng saponins play a significant role in exerting multiple therapeutic effects. This review covers their chemical structure and classification, as well as their pharmacological activities, i
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N, Mishra D., Gomare K. S, and Sheelwant S. V. "GC-MS Analysis and Phytochemical Screening of Indigofera tinctoria (Linn.) Leaf Extract Characterizing its Medicinal Use." International Journal of Ayurvedic Medicine 11, no. 2 (2020): 289–99. http://dx.doi.org/10.47552/ijam.v11i2.1540.

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Indigofera tinctoria (Linn.), a perennial shrub belongs to the family Fabaceae (Leguminosae) is well known in Indian system of medicines for its traditional uses. The present study was carried to find out the possible bioactive components in the leaves of this plant in ethanol extract by Gas Chromatography-Mass Spectrometry (GC-MS) analysis and the therapeutic uses of each compound as per PASS and other database. The mass spectra of the extract found compounds that were matched with the National Institute of Standards and Technology (NIST version 5.7.1) library database. The GC-MS study observ
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Dissertations / Theses on the topic "Glycosides – therapeutic use"

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Meloncelli, Peter J. "The synthesis of several azasugars, glycosylated azasugars and disaccharides of biological interest." University of Western Australia. School of Biomedical, Biomolecular and Chemical Sciences, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0052.

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[Truncated abstract] The development of several carbohydrate-based pharmaceuticals has stimulated an increased interest in the field of carbohydrate chemistry. The discovery of Acarbose and invention of Miglitol, treatments for type II diabetes, as well as the influenza treatments, Relenza and Tamiflu, have been largely responsible for this increased interest. These treatments operate by the inhibition of glycoside hydrolases, a group of enzymes important in a variety of biological processes. This thesis involves the study of a group of glycoside hydrolase inhibitors known as azasugars, which
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"Antidepressant-like effects of total glycosides of peony and its possible mechanisms." Thesis, 2010. http://library.cuhk.edu.hk/record=b6074989.

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Finally, the neuroprotective effects of TGP against corticosterone-induced neurotoxicity in rat pheochromocytoma (PC12) cells, an in vitro experimental model of depression were studied. The results showed TGP treatment dose-dependently protected the cells against corticosterone-induced toxicity. The cytoprotection afforded by TGP treatment was shown to be associated with an enhanced antioxidant activity, and increased expressions of neurotrophins including brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3.<br>Secondly, the antidepressant-like effect of TGP was evaluated
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"Antioxidative and vascular effects of kudingcha (Ligustrum purpurascens)." 2000. http://library.cuhk.edu.hk/record=b5890462.

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Wong Yuen Fan.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.<br>Includes bibliographical references (leaves 134-150).<br>Abstracts in English and Chinese.<br>ACKNOWLEDGMENTS --- p.i<br>ABSTRACT --- p.ii<br>LIST OF ABBREAIATIONS --- p.vii<br>TABLE OF CONTENTS --- p.ix<br>Chapter Chapter 1 --- General introduction<br>Chapter 1.1 --- History of Kudingcha --- p.1<br>Chapter 1.2 --- Classification of Kudingcha --- p.1<br>Chapter 1.3 --- Composition of Kudingcha --- p.3<br>Chapter 1.4 --- Introduction to phenylethanoid glycosides --- p.4<br>Chapter 1.4.1 --- Isolation and purif
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Books on the topic "Glycosides – therapeutic use"

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Linda, Comac, ed. The skin cancer answer. Avery Pub. Group, 1999.

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Recent Advances in Ginseng and Glycosides Research. Nova Science Pub Inc, 2013.

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Iminosugars: From synthesis to therapeutic applications. John Wiley and Sons, 2007.

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(Editor), Philippe Compain, and Olivier R. Martin (Editor), eds. Iminosugars: From Synthesis to Therapeutic Applications. Wiley, 2007.

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Wilhelm, Kirch, ed. Digitalis glycosides: Vascular sites of action. W. Zuchschwerdt Verlag, 2002.

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Lane, William I., and Linda Comac. The Skin Cancer Answer: The Natural Treatment for Basal and Sqamous Cell Carcinomas and Keratoses. Avery, 1998.

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1939-, Dumitriu Severian, ed. Polysaccharides in medicinal applications. M. Dekker, 1996.

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Lapostolle, Frédéric, and Stephen W. Borron. Management of digoxin poisoning. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0323.

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Despite a gradual decline in the clinical use of digitalis glycosides, digitalis toxicity continues to be responsible for substantial morbidity and mortality, particularly among the elderly. Digitalis poisoning may occur acutely, after intentional overdose, but is more often seen as the result of chronic intoxication among patients receiving digitalis therapy. Clinical findings in chronic digitalis poisoning are often subtle. The astute clinician will enquire about digitalis use in older patients with vague complaints and will not be dissuaded from considering digitalis toxicity in the face of
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Book chapters on the topic "Glycosides – therapeutic use"

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Jung, L. M. "Therapeutic use of digitalis until the time of William Withering." In Cardiac Glycosides 1785–1985. Steinkopff, 1986. http://dx.doi.org/10.1007/978-3-662-11292-2_3.

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