Relevant bibliographies by topics / Glycosylation / Dissertations / Theses
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Dissertations / Theses on the topic 'Glycosylation'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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1

Seward, Christopher M. P. "Stereoselective glycosylation chemistry." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270281.

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2

Rising, Thomas W. D. F. "Glycosylation using endohexosaminidases." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436989.

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3

Yassine, Hanane. "Caractérisation d’endocan murin : dualité fonctionnelle pro- ou anti-tumorale de l’endocan selon son statut de glycosylation. Etude des mécanismes d’action anti-tumorale." Thesis, Lille 2, 2014. http://www.theses.fr/2014LIL2S029/document.

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Une tumeur nécessite un approvisionnement en oxygène et en nutriments pour sa croissance mais aussi pour la dissémination à distance vers d’autres organes. L’angiogenèse tumorale est le phénomène exploité par la tumeur pour accomplir ses besoins. Les «Tip cells » situées à l’extrémité des capillaires en bourgeonnement initient et guident la croissance des néovaisseaux. Ces cellules sont considérées actuellement comme une cible thérapeutique pertinente pour les médicaments anti-angiogéniques. De nombreuses études ont permis d’identifier un cluster de marqueurs moléculaires exprimés de manière p
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4

Rivinoja, A. (Antti). "Golgi pH and glycosylation." Doctoral thesis, University of Oulu, 2009. http://urn.fi/urn:isbn:9789514292699.

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Abstract Glycans, as a part of glycoproteins, glycolipids and other glycoconjugates, are involved in many vital intra- and inter-cellular tasks, such as protein folding and sorting, protein quality control, vesicular trafficking, cell signalling, immunological defence, cell motility and adhesion. Therefore, their correct construction is crucial for the normal functioning of eukaryotic cells and organisms they form. Most cellular glycans are constructed in the Golgi, and abnormalities in their structure may derive, for instance, from alkalinization of the Golgi lumen. In this work we show th
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5

Anttonen, Katri Pauliina. "Protein glycosylation in actinomycetes." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=92515.

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The aims of this project were to study the glycoproteome in two mycobacteria; <i>M. marinum</i> and <i>M. smegmatis</i>, and to assess the role of protein glycosylation by knocking out the Pmt homologues.  Due to technical difficulties in the construction of knock out strains in mycobacteria, the aims were changed to further elucidate the protein <i>O</i>-glycosylation pathway identified in <i>S. coelicolor.  </i>Reverse transcriptase PCR was used to show that <i>pmt, ppm1 </i>and the putative <i>ppm2 </i>(SCO1014) are expressed throughout the complex life cycle of <i>S. coelicolor.  </i>The p
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6

Green, L. "Studies in glycosylation methodology." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599657.

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This thesis is divided into two sections. The first section covers techniques, strategies and mechanisms of oligosaccharide formation, illustrated with both literature and the author's results, highlighting the many subtleties involved in performing a glycosylation. These include attempts at <I>trans</I>-glycoside formation on a polymer support without the use of an acetyl directing group and the curious failure of an acetyl group to direct a glycosylation in the synthesis of a lactosamine derivative. The second section describes studies towards the development of stereocontrolled glycosylatio
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7

Karg, Saskia Ruth. "N-glycosylation engineering in tobacco /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17989.

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8

Kameh, Homa. "Aberrant glycosylation in HEMPAS patients." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ28786.pdf.

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9

Harthill, Jean Elizabeth. "N-glycosylation of horseradish peroxidase." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292612.

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10

Kaloo, Sara. "Glycosylation of Carbohydrates by Glycosyltranferases." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508556.

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11

Allen, Alice. "IgA glycosylation in IgA nephropathy." Thesis, University of Leicester, 1995. http://hdl.handle.net/2381/35028.

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IgA nephropathy (IgAN) is a common glomerulonephritis characterised by deposition of IgA1 in the glomerular mesangium The underlying abnormality lies within the IgA system rather than the kidney, and modest irregularities of IgA biology have been described, but the mechanisms involved in IgA1 deposition and glomerular injury remain elusive. A few reports have suggested an abnormality of the carbohydrate component of IgA1 in IgAN. These studies sought to confirm and further characterise the putative glycosylation defect and to identify its biochemical basis. Lectin binding assays were developed
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12

Keenan, Tessa. "Protein O-glycosylation in Streptomyces." Thesis, University of York, 2016. http://etheses.whiterose.ac.uk/16889/.

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Previously, a protein O-mannosyl transferase (Pmt, SCO3154) and a polyprenol phosphate mannose synthase (Ppm1, SCO1423) were found to be required for the glycosylation of PstS, a phosphate binding protein, in the bacterium Streptomyces coelicolor. Bacteria in this genus are prolific producers of antibiotics and are often phenotypically resistant to multiple antibiotics. S. coelicolor pmt and ppm1 deficient mutants were hypersusceptible to cell-wall active antibiotics, suggesting that the protein modification could be required for cell wall and membrane homeostasis. The aim of this project was
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13

Cox, Daniel. "New approaches to stereocontrolled glycosylation." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:b3eb90c9-3149-4761-930f-391607ee134c.

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The conceptually simple process of linking carbohydrate units by glycosylation has proven to be one of the most difficult synthetic processes to control from a stereochemical perspective. In particular it is the stereocontrolled synthesis of 1,2-cis glycosyl linkages (e.g. α-glucosides, β-mannosides) which poses the most difficult challenge. The research presented in this thesis describes new ways in which stereocontrol in glycosylation reactions can be achieved. New methods of neighbouring group participation have been explored, utilising novel protecting groups at the 2-postion of a series o
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14

Singh, Govind Pratap. "New approaches to stereocontrolled glycosylation." Thesis, University of Canterbury. Chemistry, 2015. http://hdl.handle.net/10092/11126.

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The conceptually simple process of linking carbohydrate units by glycosylation has proven to be one of the most difficult synthetic processes to control from a stereochemical perspective. In particular it is the stereocontrolled synthesis of 1,2-cis glycosyl linkages (e.g. α-glucosides, β-mannosides) which poses the most difficult challenge. The research presented in this thesis describes new ways in which stereocontrol in glycosylation reactions can be achieved. New methods of neighbouring group participation have been explored, utilising novel protecting groups at the 2-postion of a series
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15

Lige, Bao. "Role of glycosylation in peanut peroxidase." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0006/NQ42539.pdf.

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16

Leaney, Sarah J. "GIT : glycosylation 'via' inter/intramolecular transfer." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409812.

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17

Warren, C. E. "N-glycosylation in mice and rats." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315795.

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18

McAulay, Kathrine. "Glycosylation of Staphylococcus aureus surface proteins." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555122.

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Staphylococcus aureus is a major human pathogen, causing a wide spectrum of superficial and systemic infections. With the advent of methicillin resistant Staphylococcus aureus (M RSA) and the increasing spread of antibiotic resistance it has become clear that novel approaches must be taken to control S. aureus. Glycosylation, the modification of proteins with carbohydrate moieties, was long considered a process confined to eukaryotes; however, the last 3 decades have seen increasing awareness and characterisation of glycosylation systems in bacteria, including many pathogens In this study S. a
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19

Day-Williams, Michaela Joanne. "Polar flagellum glycosylation in aeromonas caviae." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515262.

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20

Hong, Sung You. "Surface glycosylation and filling of nanotubes." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509960.

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21

Kong, Leopold. "HIV-1 gp120 : flexibility and glycosylation." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533859.

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22

Hills, Anna E. "Control of monoclonal antibody N-glycosylation." Thesis, University of Kent, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.344101.

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23

Huffman, Jennifer Elizabeth. "Genetic analysis of protein N-glycosylation." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10038.

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The majority of human proteins are post-translationally modified by covalent addition of one or more complex oligosaccharides (glycans). Alterations in glycosylation processing are associated with numerous diseases and glycans are attracting increasing attention both as disease biomarkers and as targets for novel therapeutic approaches. Using a recently developed high performance liquid chromatography (HPLC) method for high-throughput glycan analysis, genome-wide association studies (GWAS) of 33 directly measured and 13 derived N-glycan features were performed in 3533 individuals from four Eur
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24

Gorbea, Carlos M. "Expression and glycosylation of meprin isoforms." Diss., This resource online, 1992. http://scholar.lib.vt.edu/theses/available/etd-07282008-134351/.

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25

Taylor, Thomas Alex. "Investigations into novel enzymatic glycosylation methods." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:3bfd1078-79d8-4c68-83a0-0bb5343583eb.

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Glycosylation is one of the most prevalent post-translational modifications found on human proteins. There is a great interest in developing new methodologies for the synthesis of glycoproteins, both to elucidate the functions of glycans on proteins and to exploit the beneficial properties they can confer on biotherapeutics. Here, research was carried out investigating enzymatic techniques to achieve the formation of homogenous glycoproteins. EndoS was the first enzyme investigated. EndoS natural activity is for the hydrolysis of glycans specifically from IgG, yet there has been research into
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26

Mas, Eric. "Glycosylation de la lipase sels biliaires dépendante du pancréas : Glycosylation de la lipase sels biliaires dépendante du pancréas." Aix-Marseille 2, 1995. http://www.theses.fr/1995AIX22028.

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La lipase sels biliaires-dependante (bsdl) est une enzyme lypolitique de la secretion pancreatique. Dans un premier temps, nous avons montre que la n-glycosylation de la bsdl, issue d'un sujet sain, est de type biantennaire complexe et elle presente 12 a 14 structures o-glycosylees de type (gal betal-3 galnac)-ser/thr plus ou moins sialylees et/ou fucosylees. La n-glycosylation est aussi essentielle a l'expression d'une bsdl totalement active et a sa secretion. Cependant, les inhibiteurs de la maturation de la n-glycosylation n'influent ni sur l'activite ni sur la secretion de l'enzyme. La str
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27

Zerbib, Marie. "Etude de la glycosylation de flavanols dans le raisin et incidence dans les vins." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTG051/document.

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Les flavan-3-ols appartiennent à la famille des polyphénols retrouvés dans diverses plantes et majoritairement dans le raisin. Ils jouent un rôle primordial dans les mécanismes de défense des plantes, influent sur les propriétés organoleptiques du vin et sont potentiellement bénéfiques au niveau de la santé humaine. La voie de biosynthèse des flavanols monomères est décrite dans la littérature. Cependant, les mécanismes de formation des proanthocyanidines (polymères) sont inconnus à ce jour. Des études ont montré que les flavanols glycosylés sont des intermédiaires potentiels dans la biosynthè
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28

Luz, Johanna Da. "Aspects of N-glycosylation in human IgE /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-130-6.

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29

Ho, Ming-Kai 1978. "Characterization of glycosylation of prolactin in galliformes." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98724.

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Prolactin (PRL) is a highly versatile hormone in terms of its biological functions. In Galliformes, high levels of PRL are associated with incubation behaviour and hatching. It has been shown that these high levels of PRL were associated with an increased ratio of glycosylated PRL (G-PRL) versus non-glycosylated PRL (NG-PRL) in turkey (Bedecarrats et al., 1999a). This suggests that glycosylation of PRL is related to its proper function during those stages of life. However, the mechanism(s) controlling post-translational modification of PRL are unknown. In order to investigate genes associated
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30

Critchley, Alison. "Congenital disorders of glycosylation and disease pathogenesis." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424758.

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31

Al-Ghouleh, Abeer. "The role of glycosylation in allergen recognition." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/12103/.

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This project is an attempt to have a better understanding of the role of carbohydrates in recognition and uptake of allergens by the innate immune system. Glycosylation analysis of different allergens like Der p 1, Fel d 1, Ara h 1, Ber e 1, Der p 2, Bla g 2, Can f 1, Bromelain and Papain was made using labelled lectins that can detect specific carbohydrate moieties on proteins to reveal their pattern of glycosylation. These experiments showed that all major allergens are glycosylated and this represented a major first step towards demonstrating a link between glycosylation and allergen recogn
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32

McKenzie, Samuel Noel. "Asymmetric Control of the Diastereoselectivity of Glycosylation." Thesis, University of Canterbury. Chemistry, 2011. http://hdl.handle.net/10092/5931.

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Diastereoselective control of glycosylation still remains a difficult task. Therefore, new glycosylation methods using asymmetric catalysis were developed to control the diastereoselectivity. Two systems were developed and each focused on a separate type of glycosyl donor. In the first system, glycosyl halides were subjected to reaction conditions inspired by Hamilton et al., who effectively had controlled the substitution of a racemic chloroamine by an alcohol. Asymmetric control of glycosylation was achieved through this adapted catalytic system. Both enantiomers of the catalyst ((R) and (S)
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33

Mann, Alexander Charles. "Serum protein glycosylation in alcoholic liver disease." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323479.

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34

Chen, Qiushi. "Mass spectrometric investigation of biomedically important glycosylation." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/56202.

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Glycobiology is the comprehensive study of the structure, biosynthesis, function and evolution of saccharides which are also named sugars or glycans. Glycosylation is a type of modification in which sugars are added to another molecule, such as a protein molecule or a ceramide. Abnormal glycosylation is frequently associated with diseases such as cancer and immune responses. Defining glycan structures is therefore important for understanding glycan function in health and disease. In addition, identification of glycan populations can provide essential information for further research on glycopr
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35

Yuk, Inn Huam Yvonne. "Protein expression and glycosylation in CHO cells." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/8201.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2001.<br>Includes bibliographical references (p. 193-207).<br>A successful mammalian cell culture process depends on sufficient expression and correct glycosylation of the recombinant product. Low product titer and inconsistent protein glycosylation constitute two major problems frequently encountered in biopharmaceutical production. Using Chinese Hamster Ovary (CHO) cells expressing recombinant human interferon-gamma (IFN-y) as the model system, this thesis investigated strategies that can potentially enhan
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36

Mérit, Xavier. "Protéines G et glycosylation chez Aspergillus niger." Lyon 1, 1991. http://www.theses.fr/1991LYO10086.

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Nous avons mis en evidence chez aspergillus niger, une activite gtpase qui est souvent une des fonctions des proteines g, connues pour fixer et hydrolyser le gtp. L'utilisation d'analogues non hydrolysables du gtp et du gdp a permis d'etudier les modalites de leur fixation et la localisation des proteines impliquees. Un fractionnement cellulaire met en evidence des localisations distinctes pour ces proteines particulieres. En effet, apres electrotransfert sur nitrocellulose, les anticorps anti-site de fixation du gtp revelent l'existence de 6 proteines g dans le cytosol. Une separation des fra
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37

Fernandes, Elisabete Cristina Nunes. "Humoral responses against esophageal cancer-associated glycosylation." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/11301.

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Mestrado em Bioquímica Clínica<br>O cancro de esófago (CE) tem um mau prognóstico e uma baixa taxa de sobrevivência. É diagnosticado tardiamente, por endoscopia, um método invasivo que carece de especificidade e sensibilidade. Atualmente, não existem biomarcadores para melhorar a precisão do diagnóstico. A transformação maligna é acompanhada por alterações no padrão de glicosilação das células, que são utilizadas no diagnóstico não-invasivo, monitorização da doença, bem como terapêutica. Além disso, as proteínas exibindo glicosilação alterada são capazes de induzir respostas humorais. Os auto
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38

Borentain, Patrick. "Voies de la glycosylation et carcinome hépatocellulaire." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM5047.

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La glycosylation est un processus enzymatique permettant l'ajout de sucres à des composés (sucres, lipides ou protides), modifiant ainsi leurs propriétés. La glycosylation est impliquée dans la détoxification des xénobiotiques et des variations d'activité des enzymes responsables ont été identifiées comme facteur de risque de cancer en particulier dans les organes exposés aux xénobiotiques. Dans la première partie de notre travail nous étudions l'impact des polymorphismes génétiques de certaines enzymes responsables de la détoxification (UGT1A7, GST et XRCC1) sur le risque de carcinome hépatoc
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39

Wood, Alison. "N-linked protein glycosylation in Helicobacter species." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/nlinked-protein-glycosylation-in-helicobacter-species(ef97ffdd-aca4-40ff-b52b-7b8ca030bc82).html.

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N-linked protein glycosylation involves the transfer of a glycan onto an Asparagine residue (N) of a polypeptide chain. It is common in Eukaryotes and has recently been observed in Prokaryotes, most notably in Campylobacter jejuni. The C. jejuni N-linked glycosylation system is encoded on a single pgl gene locus that also functions when expressed in Escherichia coli. The key enzyme involved in N-linked protein glycosylation is encoded by the pglB gene and transfers lipid-linked glycan onto N residues of glycoproteins in the periplasm. It is clear from accumulating genome sequence data that pgl
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40

Lowry, Rebecca. "Glycosylation of the Aeromonas caviae polar flagellum." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/9503/.

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The bacterial flagellum is an important appendage at the bacterial cell surface, not only for motility, but for adherence to host cells, and therefore has an extensive role in bacterial colonisation and virulence. A number of pathogenic bacteria modify their flagellins with nonulosonic acids, such as Aeromonas, Campylobacter and Helicobacter species, via an O-linked glycosylation process. This modification is essential for their ability to form flagella, thus having implications in pathogen virulence. However, the role of flagellin glycosylation is currently undetermined. The mesophilic aeromo
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41

Delannoy, Philippe. "Etude des modifications de la glycosylation de la fibronectine des cellules transformées : Conséquence sur l'affinité de la fibronectine pour le collagène." Lille 1, 1989. http://www.theses.fr/1989LIL10069.

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L'analyse comparée des glycanes de fibronectine de fibroblastes de rein de hamster normaux ou transformés par le virus h5v a montré que les glycanes majeurs de la fibronectine de fibroblaste de 1er type diffèrent du second type. Étude des activités sialyltransférases de ces cellules
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42

Lin, Chaoqi. "Synthesis and study of photoswitchable glycomacrocycles." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLN039.

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Grace à leur excellente propriété photochromique, les dérivés d’azobenzène trouvent de plus en plus d’applications pour le photocontrôle spatio-temporel de conformations moléculaires, de réactivités chimiques, des activités biologiques et pharmaceutiques. Dans ce contexte, introduire un motif photochromique dans les macrocycles contenant de glucides représente une approche excitante afin de moduler par la lumière les propriétés physicochimiques, chimiques et biologiques de cette unique classe de molécules qui attirent d’attention croissante en chimie médicinale et en science des matériaux.Deux
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43

Marchal, Ingrid. "Modification des capacités de glycosylation des cellules d'insectes." Phd thesis, Université des Sciences et Technologie de Lille - Lille I, 2001. http://tel.archives-ouvertes.fr/tel-00258437.

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L'utilisation thérapeutique de glycoprotéines recombinantes produites dans le système baculovirus-cellules d'insectes reste limitée par le potentiel de glycosylation de ces cellules, qui produisent essentiellement des structures O- et N-glycanniques courtes. Notre travail s'inscrit donc dans un effort global d'"humanisation" de la glycosylation des protéines produites dans les cellules de Lépidoptères.<br />Nous nous sommes d'abord attachés à comprendre la voie de maturation des N-glycannes dans des cellules Sf9. L'utilisation d'inhibiteurs de la maturation ou du trafic intracellulaire nous a
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44

Alonzi, Dominic S. "Cellular Mechanism of Glycosylation Inhibition by Imino Sugars." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487138.

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Glycosylation is the most common posttranslational modification of proteins. It is a complex process involving many functional proteins and resulting'in a great diversity of structures. The retention of glucose residues on N-linked oligosaccharides following ER a-glucosidase inhibition by imino sugars such as N-butyl deoxynojirimycin, increases the protein misfolding and the amount of glycoprotein destined for degradation via the endoplasmic reticulum associated degradation (ERAD) pathway. Intracellular peptide N-glycosidases (PNGases) act generating free oligosaccharides (FOS) and the protein
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45

Rosenlöcher, Julia [Verfasser]. "Optimizing the glycosylation of recombinant proteins / Julia Rosenlöcher." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1112133437/34.

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46

Tey, Lai-Hock. "Studies of site-selective glycosylation of dihydrofolate reductase." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/55798/.

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Glycosylation is important for many molecular processes, although how glycosylation contributes to glycoprotein structure and function is not entirely clear. Other than that, the study of many of these events is complicated by the fact that natural glycoproteins normally occur as mixtures of glycoforms, therefore the isolation or synthesis of homogenous glycoproteins is an important task. Previous studies on deglycosylated proteins have shown that glycosylation reduces their catalytic activity and increase thermal stability. Therefore, we hypothesize that similar effects may be observed in the
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47

Hamid, Umi Marshida Abd. "Glycosylation-based approaches for potential breast cancer biomarkers." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540155.

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48

Anderson, Ross C. "Immunoassays for glycosylation of alpha-1-acid glycoprotein." Thesis, University of Sunderland, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337295.

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49

Fontinopoulou, Angeliki. "Investigating the glycosylation of recombinant glycoproteins with lectins." Thesis, University of Newcastle Upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432779.

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50

Jowett, Adrian K. "Glycosylation patterns during development of mouse molar teeth." Thesis, University of Manchester, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304035.

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